JP6263346B2 - Skin preparations and cosmetics - Google Patents

Description

  The present invention relates to an external preparation for skin and a cosmetic containing astaxanthins and glycogen, and more preferably a hydrated oil such as rosin acid ester.

  A fringe line (legal line) is two wrinkles that extend from both sides of the human nose to both ends of the lips, and often starts to appear after middle age mainly due to aging. Causes include ultraviolet rays, smoking, and vitamin C deficiency. The tangled line is a slack caused by drooping of the skin tissue and subcutaneous fat due to the decrease in elasticity of the dermis due to gravity, and the fineness of the dermis caused by dryness and aging of the epidermis, and the elasticity of the dermis is reduced. It is usually differentiated from dermal wrinkles such as wrinkles in the corners of the eyes, vertical wrinkles between the eyebrows, horizontal wrinkles in the forehead, wrinkles around the mouth, and the like caused by facial wrinkles.

  A lot of beauty tools such as pack sheets, masks, massage devices, etc. have been proposed for the improvement of funnel lines, but plants such as rhododendron genus lingonberry as a fungus improver for oral intake. And a collagen production promoter (Patent Document 1) is a skin external preparation containing 5-aminolevulinic acid and an iron compound (Patent Document 2) and algillin acting on facial muscles And a skin cosmetic liquid comprising an aqueous solution containing at least a hyaluronic acid having a weight average molecular weight of 500,000 to 4,000,000 or a salt thereof (Patent Document 3), and a matrix containing a Matricaine substance that promotes repair of collagen and elastin Patent Document 4) and a thiol group-containing polymer for producing a tissue augmentation implant whose base polymer is a polysaccharide (Patent Document 5) , A cosmetic composition in the form of an oil-in-water emulsion containing a fractal particle-based gel and a polymer such as polyglycol (Patent Document 6), or a composition having a skin irritation reducing action containing trans-tert-butylcyclohexanol Products (patent document 7), polymer gel preparations containing chlorin e4 and vitamin C (patent document 8), polysaccharide base materials such as chitosan, carboxymethylcellulose, carboxymethylchitosan, synthetic hydrophilic polymers such as polyethylene glycol, And a hydrogel composition comprising a crosslinking agent (Patent Document 9), at least one crosslinked polymer and at least one branched polymer, both of which are castor oil, ricinoleic acid and / or hydroxystearic acid Biologically allowed including as a base one or more selected from Gel (Patent Document 10) are known respectively to be.

  On the other hand, astaxanthin is a carotenoid (a kind of natural pigment) having a high antioxidant action as shown by the following chemical formula. As a wrinkle improving agent containing astaxanthin, a photoaging inhibitor containing astaxanthin (Patent Document 11) Astaxanthin-containing water-soluble composition containing astaxanthin, dextrin and casein (patent document 12), cosmetic composition containing astaxanthin, collagen and collagen peptide (patent document 13), astaxanthin and dermal matrix component A wrinkle improving composition containing a compound having a stabilizing action (Patent Document 14) and an external preparation for skin containing Adonirubin, Adonixanthin and Astaxanthin (Patent Document 15) are known.

  Glycogen is a homopolysaccharide composed of D-glucose, and is averaged from a sugar chain of α-1,4 bonds of glucose to a ratio of about one every about three units of glucose with α-1,6 bonds. Branches having a polymerization degree of 12 to 18 are formed, and further, a branched network structure is formed. As a wrinkle improving agent containing glycogen, an external preparation for skin containing phytoglycogen as an active ingredient (Patent Document 16), an external preparation for skin containing hyaluronic acid or a salt thereof and phytoglycogen (Patent Document 17), pearls, A skin external preparation (Patent Document 18) containing at least one selected from conchiolin, succinic conioline, collagen, elastin, acidic mucopolysaccharide, shellfish acidic polysaccharide and glycogen, or one or more of glycogen and anti-inflammatory agent An external preparation for skin (Patent Document 19) and a composition (Patent Document 20) for promoting the production of at least one component selected from the group consisting of hyaluronic acid and elastin in epidermal cells, including glycogen, are known. It has been.

JP 2013-14561 A WO2006 / 117785 JP 2007-50126 A JP 2008-37774 A Special table 2010-512859 gazette Special table 2010-513544 gazette Special table 2012-523381 gazette Special table 2013-508390 gazette Special table 2013-510175 gazette Special table 2013-518095 gazette JP 2002-128651 A WO2009 / 048120 JP 2009-13129 A JP 2011-63563 A Japanese Patent Application Laid-Open No. 2012-1558569 JP 11-255657 A JP 2000-95660 A JP 2003-300821 A JP 2003-335651 A JP 2012-62273 A

  An object of the present invention is to provide an external preparation for skin and cosmetics for improving constriction lines, that is, an external preparation for skin and cosmetics that make constrictions inconspicuous by pulling up the constriction lines. There is.

  Astaxanthin and glycogen are both known to have a wrinkle-improving effect, but their individual use and other wrinkle-improving agents have not been sufficient to improve the sagittal line (sag). The present inventors have developed an external preparation for skin and a cosmetic that improve a constriction line (sag) by combining astaxanthins and glycogen. Furthermore, by combining specific oils, we have developed a topical skin preparation and cosmetics that can improve the remarkable constriction (sagging) after immediate and long-term continuous use.

That is, the present invention is as follows.
(1) A skin external preparation or an external skin cosmetic for improving a constriction line, comprising astaxanthins and glycogen.
(2) The external preparation for skin or external cosmetic for skin according to the above (1), wherein the content ratio of astaxanthins and glycogen is 1: 0.5 to 20.
(3) The external preparation for skin or cosmetic for external use according to the above (1) or (2), which further contains a water-holding oil.
( 4 ) The skin external preparation or the skin external cosmetic according to any one of (1) to (3), wherein the glycogen is a plant-derived glycogen.
( 5 ) The skin external preparation or skin external preparation according to ( 4 ), wherein the plant-derived glycogen is corn-derived glycogen.
( 6 ) The external preparation for skin or external cosmetic for skin according to any one of the above ( 3 ) to ( 5 ), wherein the oil-holding oil has a viscosity at 30 ° C. of 10,000 mPa · s or more.
( 7 ) The skin external preparation or the skin external cosmetic described in ( 6 ) above, wherein the water-holding oil is one or more selected from the group consisting of a rosin acid ester and a dimer acid ester.
( 8 ) The external preparation for skin or the external preparation for skin according to ( 7 ) above, wherein the rosin acid ester is hexa (12-hydroxystearic acid / stearic acid / rosin acid) dipentaerythrityl.
( 9 ) The external preparation for skin or cosmetic for external use according to any one of the above (1) to ( 8 ), which is an oil-in-water emulsified beauty liquid.

  According to the external preparation for skin and cosmetics of the present invention, the constriction line (sag) can be improved by pulling up the constriction line to make the constriction line inconspicuous or inconspicuous.

It is the photograph before and behind use of Example 2. FIG.

  The skin external preparation and cosmetics of the present invention are not particularly limited as long as they are skin external preparations and cosmetics for improving the spine line containing astaxanthins and glycogen. This refers to raising the constriction line (slack) to make the confinement line less noticeable or less noticeable. The skin-line improving skin external preparation and cosmetics of the present invention preferably contain a water-holding oil in addition to astaxanthins and glycogen.

  Examples of the astaxanthins include ester derivatives thereof as well as astaxanthin (free form). Examples thereof include amino acid esters such as glycine and alanine, carboxylic acid esters such as acetate and citrate and salts thereof, phosphorus Inorganic acid esters such as acid esters and sulfates and their salts, glycosides such as glucosides, highly unsaturated fatty acids such as eicosapentaenoic acid and docosahexaenoic acid, unsaturated fatty acids such as oleic acid and linoleic acid, palmitic acid, Examples thereof include monoesters selected from fatty acid esters selected from saturated fatty acids such as stearic acid, and the same or different diesters. These astaxanthins may be those produced by extraction / purification from natural products such as krill, salmon, trout, cypress, red yeast, Haematococcus algae, or may be produced by organic chemical synthesis. Specific examples of haematococcus algae extracts include Haematococcus pluvialis, Haematococcus lacustris, Haematococcus capensis, and Haematococcus draebagen. And Haematococcus zimbabwiensis. The extraction solvent for obtaining astaxanthins from natural products may be an aqueous solvent or an organic solvent. As the organic solvent, methanol, ethanol, isopropanol, acetone, 1,3-butylene glycol, ethylene glycol, propylene glycol, glycerin, ethyl acetate, ether, hexane, or the like can be used. Also, carbon dioxide in a supercritical state can be used. These solvents may be used alone or in combination of two or more. In addition, as commercially available products, for example, ASTOTS-S, -5O, -10O, etc. manufactured by Takeda Shiki Co., Ltd., Asteril Oil 50F, 5F, etc. manufactured by Fuji Chemical Industry Co., Ltd. Astaxanthin-5C, 20C, and ASTABIO (registered trademark) AR1, AR5 manufactured by Biogenic Co., Ltd.

  Moreover, as content of astaxanthin in the skin external preparation and cosmetics of this invention, it is 0.00001-0.5 mass%, Preferably it is 0.0001-0.05 mass%, More preferably, it is 0.005-0. 0.01% by mass, more preferably 0.001 to 0.005% by mass can be suitably exemplified.

  The glycogen preferably has an average molecular weight of 200,000 to 2,000,000, more preferably 500 to 1,000,000. Examples include shellfish such as scallops, abalone, oysters, mussels and pearl oysters, animal glycogen derived from cattle, pig liver, etc., and plant glycogen derived from corn, barley, rice, potato, tapioca, etc. Although it is possible, plant glycogen is preferred. As these glycogens, glycogens contained in natural products prepared by conventional methods can be used as they are, and glycogens separated and purified after enzymatic treatment can be used if necessary. Can be used. Among the above-mentioned plant glycogens, glycogen obtained by extraction from corn kernels and purification is particularly preferred. For example, Phytoglycogen (registered trademark) (average molecular weight 700,000) manufactured by Kewpie Corporation can be used. Other commercially available products of glycogen include mussel-derived biosaccharide LS, biosaccharide GY (manufactured by LABORATORIES SEROBIOLOGIQUES), and the like. Moreover, as content of glycogen in the skin external preparation and cosmetics of this invention, 0.001-5 mass%, Preferably it is 0.002-1 mass%, More preferably, it is 0.005-0.05 mass%, More preferably, 0.008-0.015 mass% can be illustrated suitably.

  Moreover, the content ratio of the said astaxanthins and glycogen in the skin external preparation and cosmetics of this invention is 1: 0.5-20, Preferably it is 1: 1-8, More preferably, it is 1: 3-5.

  In addition, it is preferable that the present invention contains a water-holding oil because the improvement of the constriction line and the sagging becomes remarkable. The “water-holding property” used in the present invention means that the water-holding power (%) measured by the following water-holding power test is 100% or more. The water holding power test method is to weigh 10 g of a sample (oil component) heated to 50 ° C. into a 200 mL beaker and stir the water at 50 ° C. while stirring at 3000 rpm with a disper mixer. The maximum amount (mass) at which water is not discharged is measured until it comes, and this value is divided by 10 g of the sample, and multiplied by 100 to evaluate as water holding power (%). Examples of such water hydrating oils include amino acid ester oils such as dioctyldodecyl lauroyl glutamate, dilauroyl glutamate (cholesteryl or phytosterol behenyl octyldodecyl), dilauroyl glutamate (cholesteryl or phytosterol octyldodecyl), castor Polyhydric alcohol fatty acid esters such as oil and shea fat, polyglycerin fatty acid esters such as hexaglycerin fatty acid ester and decaglycerin fatty acid ester, and (adipic acid, 2-ethylhexanoic acid, stearic acid) glyceryl oligoester, dipenta Erythritol hydroxystearate, hexa (hydroxystearic acid / stearic acid / rosinic acid) dipentaerythrityl, cholesterol, cholestanol, dehydro Dimers such as cholesterol derivatives such as lesterol, lanolin fatty acid cholesteryl, cholesteryl isostearate, cholesteryl hydroxystearate, cholesteryl ricinoleate, macadamia nut oil fatty acid cholesteryl, dimer linoleic acid (phytosteryl / isostearyl / cetyl / stearyl / behenyl), etc. Examples include acid esters, lanolin, adsorption-purified lanolin, liquid lanolin, reduced lanolin, acetic acid liquid lanolin, lanolin derivatives such as lanolin alcohol, hydrogenated lanolin alcohol, and lanolin fatty acid, and those modified with polyoxyalkylene.

  Among the water-holding oils, those having a viscosity at 30 ° C. of 10,000 mPa · s or more are preferable, and those having a semi-solid form are more preferable. By using these, the adhesion to the skin is improved, the skin lift-up effect is excellent, and the effect of improving the sagging line (sag) after immediate and long-term continuous use becomes remarkable.

  Furthermore, among the water-holding oils, rosin acid esters and dimer acid esters are preferable, and rosin acid esters are preferable because of their high affinity for skin.

  Two or more kinds of these water-holding oils in the external preparation for skin and cosmetics of the present invention may be contained, and the content depends on the type of external preparation for skin and cosmetics, etc., but is 0.1 to 10% by mass. Preferably, 0.5-5 mass%, More preferably, 2-4 mass%, More preferably, 2.5-3.5 mass% can be illustrated suitably. Moreover, the content ratio of the said water-holding oil agent, astaxanthins, and glycogen in the skin external preparation and cosmetics of this invention is 10-1000 with respect to the total amount of astaxanthins and glycogen, Preferably it is 50-500. More preferably, it is 100-400.

  In the composition of the present invention, as long as the effects of the present invention are not impaired as required, in addition to the above-mentioned components, components used for skin external preparations and cosmetics, that is, water (purified water, hot spring water, Deep water etc.), oil agent, surfactant, metal soap, gelling agent, powder, alcohol, water-soluble polymer, film forming agent, resin, UV protection agent, inclusion compound, antibacterial agent, perfume, deodorant Agent, salt, pH adjuster, refresher, animal / microbe-derived extract, plant extract, blood circulation promoter, astringent, antiseborrheic agent, whitening agent, anti-inflammatory agent, active oxygen scavenger, cell activator, Moisturizers, chelating agents, keratolytic agents, enzymes, hormones, vitamins and the like can be added.

  The cosmetics of the present invention include basic cosmetics such as lotions, creams, milky lotions, and beauty essences, hair cosmetics such as shampoos, rinses, and treatments, makeup cosmetics such as liquid foundations, base milks, and tanning. Cosmetics such as stop cosmetics (including quasi-drugs) can be exemplified, and examples of external skin preparations include external medicines such as liniments, lotions and ointments. In addition, since the skin external preparation and cosmetics of this invention make the constriction line inconspicuous and the effect which improves the sagging of a cheek is remarkable, basic cosmetics and skin external preparations are preferable. Moreover, it is although it does not specifically limit as a dosage form of the skin external preparation of this invention, or cosmetics, An aqueous | water-based, oil-in-water type, a water-in-oil type etc. can be mentioned. Examples of the form of the external preparation for skin and cosmetics of the present invention include cream, gel and liquid.

  The external preparation for skin and cosmetics of the present invention can be suitably used as “for improving the constriction line” for improving the constriction line. When the effect of improving the constriction line is particularly excellent, in addition to the improvement of the constriction line, an improvement in sagging of the cheek can be expected.

  The method for producing the external preparation for skin and cosmetics of the present invention is not particularly limited, and examples thereof include a method of adding an aqueous hydrated oil to astaxanthins as necessary, and further adding and mixing glycogen and other components. be able to.

  EXAMPLES Next, although an Example is given and this invention is demonstrated, this invention is not limited at all by this Example.

[Examples 1 to 4 and Comparative Examples 1 to 5]
The oil-in-water emulsion type cosmetic liquids of Examples 1 to 4 and Comparative Examples 1 to 5 shown in the following “Table 1” were prepared by the following production method. Appropriate amount of serum is applied to 10 subjects with conspicuous lines, twice a day for two weeks in the morning and evening, and the following (a) to (b) The improvement of sagging was evaluated. In these evaluations, the degree of conspicuousness of each subject's constriction line and the degree of sagging of the cheeks were evaluated by visual judgment by three experts familiar with skin measurement. Three experts scored each subject according to the evaluation criteria, the average score of the three scores was calculated as an improvement score, and the improvement effect was judged against the criteria. The results are shown in “Table 1”.

[Evaluation criteria]
3 points: Significant improvement 2 points: Improvement 1 point: Slight improvement 0 point: No change or deterioration [Criteria]
◎: Score is 2.5 or more ○: Score is 1.5 or more and less than 2.5 Δ: Score is 0.5 or more and less than 1.5 ×: Score is less than 0.5

(Note 1) Nonion OT-221R (manufactured by NOF Corporation)
(Note 2) NIKKOL SP-10V (manufactured by Nippon Surfactant Co., Ltd.)
(Note 3) Astaxanthin-5C (manufactured by Oriza Oil Chemical Co., Ltd.)
(Note 4) Cosmol 168ARV (Nisshin Oillio Group)
(Note 5) El Dew PS-304 (Ajinomoto Co., Inc.)
(Note 6) PLANDOOL S (Nippon Seika Co., Ltd.)
(Note 7) KF-96A-100CS (manufactured by Shin-Etsu Chemical Co., Ltd.)
(Note 8) Phytoglycogen (manufactured by Kewpie)

[Production method]
A: Component No. 1-11 are mixed at 70 ° C.
B: Component No. 13 and component no. 14 and 15 are mixed.
C: Component No. 12 and component no. The remainder of 13 is mixed at 70 ° C.
D: A and C were mixed at 70 ° C., cooled to 40 ° C., and B was added and mixed to obtain a cosmetic liquid (oil-in-water emulsion type).

[Evaluation results]
As is apparent from Table 1, Examples 1 to 4 showed improvement in the constriction line and sagging after 2 weeks of continuous use. Among them, Examples 2 to 4 were remarkable in the effect of improving the constriction line, further excellent in the constriction line improvement immediately after use, and excellent in the feeling of tension. In Example 2, the improvement in sagging was also remarkable. On the other hand, Comparative Example 1 containing no astaxanthin and Comparative Example 2 containing no glycogen were insufficient in improving the enamel line and sagging. Further, Comparative Example 3 containing retinoic acid without astaxanthins and glycogen showed no improvement at all. Further, Comparative Example 4 containing retinoic acid instead of astaxanthin and Comparative Example 5 containing retinoic acid instead of glycogen were insufficient in improving the enamel line and sagging.

[Example 5: Solubilized lotion]
(Ingredient) (mass%)
1. Polyoxyethylene (40 mol) hydrogenated castor oil 0.5
2. Polyoxyethylene (12 mol) dioleate 0.3
3. Astaxanthin 5% solution (Note 3) 0.02
4.1,3-Butylene glycol 2.0
5. Glycerin 2.0
6). Ethanol 15.0
7). Tranexamic acid 2.0
8). Corn glycogen (Note 8) 0.1
9. Sodium lactate 0.2
10. Methyl paraoxybenzoate 0.1
11. Purified water balance (production method)
A. Components 1 to 6 are mixed and dissolved.
B. Components 7 to 11 are mixed and dissolved.
C. A was added to B to obtain a skin lotion.
The solubilized lotion of Example 5 was excellent in improving the constriction line and sagging.

[Example 6: Latex]
(Ingredient) (mass%)
1. Polyoxyethylene (20) sorbitan monooleate 1.0
2. Sorbitan sesquioleate 0.5
3. Glyceryl trioctanoate 0.5
4). Jojoba oil 0.5
5. Astaxanthin 5% solution (Note 3) 0.1
6). Purified water residue 7. Edetate disodium 0.1
8). Methylparaben 0.2
9. Phenoxyethanol 0.5
10. Glycerin 5.0
11. Pentylene glycol 1.0
12 Dipropylene glycol 2.0
13. Sodium lactate 0.5
14 L-ascorbic acid 2-glucoside (Note 9) 1.0
15. Corn glycogen (Note 8) 0.1
16. Xanthan gum 0.05
17. Purified water 10.0
18. Ethanol 3.0
19. Fragrance 0.05
(Note 9): Hayashibara-sha (manufacturing method)
A: Swell component 16 with component 17 heated to 70 ° C.
B: Components 1 to 5 are heated and mixed at 70 ° C.
C: Components 6 to 13 are heated and dissolved at 70 ° C., then added to B and emulsified.
D: After cooling C to room temperature, ingredients 14, 15, 18, 19 and A were added to obtain a cosmetic liquid.
The milky lotion of Example 6 had good improvement in the constriction line and sagging.

[Example 7: Sunscreen]
(Ingredient) (mass%)
1. Stearic acid 1.0
2. Monooleic acid polyoxyethylene (20 mol) sorbitan 0.5
3. Sorbitan sesquioleate 0.5
4). Behenyl alcohol 0.5
5. Glyceryl 2-ethylhexanoate 2.0
6). 2-Ethylhexyl paramethoxycinnamate 10.0
7). Diethylaminohydroxybenzoyl hexyl benzoate 2.0
8). Astaxanthin 5% solution (Note 3) 0.03
9. Tinosorb S (Note 10) 1.0
10. Octyl rearzone 0.5
11. Dipropylene glycol 10.0
12 Triethanolamine 1.0
13. Purified water residue 14. Glycerin 5.0
15.1,3-butylene glycol 5.0
16. Tinosorb M (Note 10) 1.0
17. Acrylic acid / methacrylic acid alkyl ester copolymer (Note 11) 0.2
18. Purified water 5.0
19. Corn glycogen (Note 8) 0.01
20. Citric acid 0.1
21. Disodium succinate 0.1
22. Ethanol 10.0
23. Phenoxyethanol 0.05
24. Perfume 0.02
(Note 10) BASF (Note 11) CARBOPOL 1382 (LUBRIZOL ADVANCED MATERIALS)
(Production method)
A: Components 1 to 10 are uniformly dissolved at 80 ° C.
B: Components 11 to 19 are uniformly dissolved at 80 ° C.
C: A is added to B and emulsified.
D: C was stirred and cooled, and components 20 to 24 were added to obtain sunscreen.
The sunscreen of Example 7 had good improvement in the fringe line and sagging.

[Example 8: Nonwoven fabric impregnated type packing material]
(Ingredient) (mass%)
1. Polyoxyethylene (25) Phytostanol (HLB14.5) 1.0
2. Stearyl alcohol 0.2
3. Cetanol 0.2
4). Hydrogenated soybean phospholipid 0.3
5. Propylene glycol 10.0
6). Diglycerin 8.0
7). Liquid paraffin 1.0
8). Astaxanthin 5% solution (Note 12) 0.1
9. Microcrystalline wax 5.0
10. Purified water 1.0
11. Ethanol 3.0
12 Purified water remaining amount 13. L-ascorbic acid 2-glucoside (Note 9) 2.0
14 Corn glycogen (Note 8) 0.05
15. Mussel glycogen (Note 13) 0.05
16. Hydrolyzed hyaluronic acid (molecular weight 3000) 1.0
17. Sodium hydroxide appropriate amount 18. Fragrance 0.01
(Note 12) ASTOTS-5O (manufactured by Takeda Paper)
(Note 13) Biosaccharide GY (manufactured by LABORATORIES SEROBIOLOGIQUES)
(Production method)
A: Components 1 to 6 are dissolved and mixed at 80 ° C.
B: Components 7 to 9 were heated to 80 ° C and added to A, and then component 10 heated to 75 ° C was added and emulsified.
C: This was cooled and defoamed to prepare an oil-in-water type liquid composition, and a non-woven fabric impregnated type pack material was obtained by impregnating a non-woven fabric with a stock solution in which components 11 to 18 were added and mixed.
The nonwoven fabric-impregnated type pack material of Example 8 was excellent in improving the constriction line and sagging.

[Example 9: Ointment]
(Compounding ingredients) (mass%)
1. Stearyl alcohol 18.0
2. Owl 20.0
3. Polyoxyethylene (20) monooleate 0.3
4). Astaxanthin 5% oil (Note 14) 0.1
5. Vaseline 40.0
6). Purified water residue 7. Glycerin 10.0
8). Adenosine-1-phosphate 0.5
9. Corn glycogen (Note 8) 0.05
10. Gyokuro extract 1.0
(Note 14) Astaxanthin (Bioactives Japan)
(Production method)
A. 1-5 are mixed uniformly at 70 degreeC.
B. Warm 6-9 to 70 ° C.
C. Add B to A and emulsify.
D. C was cooled and 10 was added to obtain an ointment.
The ointment of Example 9 was good in improving the constriction line and sagging.

  The external preparation for skin and cosmetics of the present invention improve the frying lines and sagging and are advantageously used in the field of makeup and beauty.

Claims (9)

A skin external preparation or cosmetic for skin use, which contains an astaxanthin and glycogen, and which improves the constriction line , which is sagging caused by drooping of skin tissue or subcutaneous fat due to gravity due to a decrease in elasticity of the dermis .   The skin external preparation or skin external cosmetic according to claim 1, wherein the content ratio of astaxanthins and glycogen is 1: 0.5 to 20.   Furthermore, the skin external preparation or the skin external cosmetic of Claim 1 or 2 containing a hydrated oil agent.   The skin external preparation or the skin external cosmetic according to any one of claims 1 to 3, wherein the glycogen is a plant-derived glycogen.   The skin external preparation or skin external cosmetic according to claim 4, wherein the plant-derived glycogen is corn-derived glycogen.   The skin external preparation or skin external cosmetic according to any one of claims 3 to 5, wherein the water-containing oil agent has a viscosity at 30 ° C of 10,000 mPa · s or more.   The skin external preparation or the skin external cosmetic according to claim 6, wherein the water-holding oil is one or more selected from the group consisting of rosin acid ester and dimer acid ester.   The rosin acid ester is hexa (12-hydroxystearic acid / stearic acid / rosin acid) dipentaerythrityl, or a skin external preparation or a skin external cosmetic according to claim 7.   The skin external preparation or the skin external cosmetic according to any one of claims 1 to 8, which is an oil-in-water emulsified cosmetic liquid.