CN105561135A - Coronary heart disease treating codonopsis pilosula-ophiopogon japonicus-panax notoginseng traditional Chinese medicine medicinal instant granules - Google Patents

Abstract

The present invention discloses coronary heart disease treating codonopsis pilosula-ophiopogon japonicus-panax notoginseng traditional Chinese medicine medicinal instant granules, wherein the traditional Chinese medicine components comprise 14-16% of codonopsis pilosula, 14-16% of salvia miltiorrhiza, 14-16% of poria cum radix pini added with cinnabar, 14-16% of radix curcumae, 14-16% of ophiopogon japonicus, 3-5% of cassia twig, 8-10% of schisandra chinensis, 8-10% of licorice root processed with honey, 5-7% of amomum villosum, and 1-2% of panax notoginseng, and leaching, concentration drying, soft material preparation, granulating, drying, palletizing and sterilization packaging are performed to prepare the coronary heart disease treating codonopsis pilosula-ophiopogon japonicus-panax notoginseng traditional Chinese medicine medicinal instant granules. According to the present invention, the coronary heart disease treating codonopsis pilosula-ophiopogon japonicus-panax notoginseng traditional Chinese medicine medicinal instant granules can effectively alleviate and eliminate coronary heart diseases and various symptoms caused by coronary artery diseases, have effects of qi benefiting, yang dredging, heart nourishing, blood circulation activation, stasis removing and pulse invigorating, and further has characteristics of significant treatment effect, rapid effect, short treatment course, and no side effect.

Description

A kind of Chinese medicinal granule electuary of Radix Codonopsis Radix Notoginseng Radix Ophiopogonis treatment coronary heart disease

Technical field

The present invention relates to the technical field of Chinese medicine, espespecially a kind of Chinese medicinal granule electuary of Radix Codonopsis Radix Notoginseng Radix Ophiopogonis treatment coronary heart disease.

Background technology

Coronary heart disease is the common a kind of cardiovascular disease of middle-aged and elderly people.The definition of World Health Organization (WHO) to coronary heart disease in 1979 is: the uneven and cardiac damage that causes between the coronary blood flow caused due to the functional change of coronary artery or organic disease and myocardial demand.The basic lesion of primary disease be supply myocardial nutrition material blood vessel---coronary artery there occurs atherosis, therefore its full name is coronary atherosclerotic heart disease, referred to as coronary heart disease.But the scope of coronary heart disease may be more extensive, also comprises inflammation, thromboembolism etc. and cause luminal stenosis or obturation.Coronary heart disease is divided into 5 large classes by World Health Organization (WHO): silent ischemia (latent coronary heart disease), angina pectoris, myocardial infarction, ischemic heart failure (ischemic heart desease) and sudden death 5 kinds of Clinical types.

Coronary heart disease is a kind of 40 years old later comparatively common heart disease.Middle-aged and elderly people is due to the decline gradually of physiological function, if not enough to calcareous picked-up, can cause calcareously disengaging in a large number from osseous tissue, this can cause osteoporosis on the one hand, the materials such as the cholesterol in osseous tissue can be made to disengage in a large number and precipitate or be attached in blood vessel wall on the other hand, increase the weight of blood vessel to help to change, thus affect blood circulation of human body.Narrower more serious coronary artery is the blood vessel of supply heart blood, if there is fatty infiltration code to make luminal stenosis under the inner membrance of this blood vessel, pile up, as which limit the flow of vessel inner blood.Blood carries oxygen, increase as heart is aerobic or Oligemia to a certain extent, will make cardiac muscle lack oxygen, cisco unity malfunction.Primary disease is equivalent to the category such as Chinese medicine " thoracic obstruction ", " chest pain ", " angina pectoris ", " precordial pain with cold limbs ".Should according to the principle of " symptomatic treatment in acute condition, radical treatment in chronic case " in treatment, blood circulation promoting and blood stasis dispelling, regulated the flow of vital energy and activated yang to lead to the pain phase.To adjust internal organs QI and blood after pain relief, training correction gas is main.

Summary of the invention

The Chinese medicinal granule electuary of a kind of Radix Codonopsis of the present invention Radix Notoginseng Radix Ophiopogonis treatment coronary heart disease, the deficiency of above-mentioned technology can be solved, Radix Codonopsis and Radix Salviae Miltiorrhizae is adopted to be aided with Poria, Radix Curcumae, Radix Ophiopogonis, Ramulus Cinnamomi, Fructus Schisandrae Chinensis, Radix Glycyrrhizae Preparata, Fructus Amomi, Typhonium flagelliforme (Lodd.) Blume 10 taste Chinese medicine, step through lixiviate, concentrate drying, soft material processed, granulation, drying, granulate, sterilization packaging prepares dissolved granule, realizes the object of Chinese medicinal granule electuary fast treating coronary heart disease.

To achieve these goals, technical solution of the present invention is: a kind of Chinese medicinal components of Chinese medicinal granule electuary of Radix Codonopsis Radix Notoginseng Radix Ophiopogonis treatment coronary heart disease: Radix Codonopsis 14% ~ 16%, Radix Salviae Miltiorrhizae 14% ~ 16%, Poria 14% ~ 16%, Radix Curcumae 14% ~ 16%, Radix Ophiopogonis 14% ~ 16%, Ramulus Cinnamomi 3% ~ 5%, Fructus Schisandrae Chinensis 8% ~ 10%, Radix Glycyrrhizae Preparata 8% ~ 10%, Fructus Amomi 5% ~ 7%, Typhonium flagelliforme (Lodd.) Blume 1% ~ 2%.

Preparation process is as follows:

(1) lixiviate: by Chinese medicinal components remove impurity, pulverizing, inserts in interlayer pot for solvent extraction, and temperature 70 C ~ 80 DEG C add 10 times of water gagings, and lixiviate 5h gets lixiviating solution and deposits; Add 8 times of water gagings again, temperature 70 C ~ 80 DEG C lixiviate 3h, merges twice decoction liquor, uses 100 mesh screen;

(2) concentrate drying: filtrate is inserted in vacuum concentration pot, setting vacuum 97kPa, temperature 55 DEG C ~ 70 DEG C, be condensed into concentrated solution, concentrated solution is 25% of Chinese medicinal components, then by concentrated solution through spraying dry, obtains lixiviate powder;

(3) soft material processed: lixiviate powder 30% adds in kneader, then add cane sugar powder 10%, dextrin 10%, dried starch 50%, be modulated to soft material medicine with the ethanol of content 50% and stick together;

(4) granulate: adopt granulation machine to produce wet shape granule;

(5) dry: dehydrate in the pneumatic drier of wet shape granule being inserted 60 DEG C;

(6) granulate: by dried granule after 1 10 mesh sieve granulate, obtain dissolved granule;

(7) sterilization packaging: after irradiating 2 ~ 3min under dissolved granule being inserted ultraviolet, every bag of 10g packs.

Chinese medicinal components of the present invention is reasonably combined, can complement each other, promote drug effect, have QI invigorating activate yang, nourish heart invigorate blood circulation, effect that blood stasis dispelling is promoted blood circulation, effectively treat all kinds of symptoms that various coronary heart disease and coronary heart disease cause, wherein:

Radix Codonopsis: there is invigorating the spleen and replenishing QI, effect of spleen invigorating lung benefiting and Radix Codonopsis has enhancing immunity, blood vessel dilating, blood pressure lowering, improves microcirculation, strengthens the effects such as hemopoietic function; Castering action is had to the leukopenia that chemotherapy radiotherapy causes;

Radix Salviae Miltiorrhizae: the effect with stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, the relieving restlessness that clears away heart-fire; Swell and ache for menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection, dysphoria and insomnia, hepatosplenomegaly, the symptom such as angina pectoris effect;

Poria: there is the functions such as eliminating dampness by diuresis, spleen invigorating, mind calming; For phlegm retention, edema, dysuria, have loose bowels, cardiopalmus, dizzy tranquilizing by nourishing the heart, diuretic tonify deficiency effect;

Radix Curcumae: the use with regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice, promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, the removing heat from blood that clears away heart-fire; And control breast abdomen side of body rib all pains, lose that the heart is demented, calentura coma, haematemesis, epistaxis, hematuria, stranguria with blood symptom effect;

Radix Ophiopogonis: there is YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire; Cough for dryness of the lung dry cough, deficiency of YIN consumptive disease, sore throat pharyngalgia, Tianjin wound be thirsty, interior-heat is quenched one's thirst, vexed insomnia, the symptom such as dryness of the intestine constipation effect;

Ramulus Cinnamomi: the effect with complement sun, promoting blood circulation, warming the spleen and stomach, normal and invigorating the liver and kidney medicine, fill blood medicine compatibility, treatment insufficiency of kidney-YANG, decline of the fire from the gate of life, cold extremities faint pulse, treat coldness and pain in the epigastrium, arthralgia due to cold lumbago with other drugs for dispelling internal cold compatibility, has the effect of significantly analgesia and anti-cancer and cancer-preventing;

Fructus Schisandrae Chinensis: have and astringe the lung, nourishing kidney, promote the production of body fluid, receive antiperspirant, arresting seminal emission; Control that the deficiency of the lung is breathed with cough, xerostomia makes thirsty, spontaneous perspiration, night sweat, impairment caused by overstrain weakness and emaciation, emission, chronic diarrhea chronic dysentery symptom;

Radix Glycyrrhizae Preparata: there is antiinflammatory and anti-allergy action, scalable body's immunity, antitumor and analgesic effect; The primary efficacy of Radix Glycyrrhizae Preparata is and middle emergency, lung moistening, removing toxic substances, coordinating the actions of various ingredients in a prescription; Be usually used in weakness of the spleen and stomach, fatigue and weakness, severe palpitation, irregularly intermittent and regularly intermittent pulse, Radix Aconiti Lateralis Preparata toxication shape can be separated;

Fructus Amomi: there is warming the spleen and kidney, therapeutic method to keep the adverse QI flowing downwards pain relieving, the chest stuffiness relieving diaphragm, dredge the stagnation of QI, except vomiting, increase effect that appetite, only cold diarrhea, appetizing, change are stagnant, help digestion, effectively can treat that stomachache distension, increased borborygmus and diarrhea, indigestion, vomiting clear water, thick fur are greasy, anemia of pregnant woman's pregnancy reactions reaction and anemia of pregnant woman's accidental cause fall and flutter, so that frequent fetal movement and the diseases such as stomachache;

Typhonium flagelliforme (Lodd.) Blume: there is hemostasis, dissipating blood stasis, detumescence, analgesic therapy; Control haematemesis, hemoptysis, epistaxis, have blood in stool, dysentery, metrorrhagia, lump in the abdomen, puerperal blood faints, retention of lochia, fall the effect of flutterring the symptoms such as blood stasis, traumatic hemorrhage, carbuncle pain;

Method of administration of the present invention: when the coronary disease condition of illness outbreak of patient, namely takes after mixing it with hot water, can effectively alleviate and eliminate all kinds of symptoms that coronary heart disease and coronary heart disease cause, have QI invigorating activate yang, nourish heart invigorate blood circulation, effect that blood stasis dispelling is promoted blood circulation; And evident in efficacy, instant effect, short treating period, has no side effect.

Detailed description of the invention

Embodiment 1

Chinese medicinal components: Radix Codonopsis 14%, Radix Salviae Miltiorrhizae 14%, Poria 14%, Radix Curcumae 14%, Radix Ophiopogonis 14%, Ramulus Cinnamomi 3%, Fructus Schisandrae Chinensis 8%, Radix Glycyrrhizae Preparata 10%, Fructus Amomi 7%, Typhonium flagelliforme (Lodd.) Blume 2%.

(2) preparation process is as follows:

1. lixiviate: by Chinese medicinal components remove impurity, pulverizing, inserts in interlayer pot for solvent extraction, and temperature 70 C ~ 80 DEG C add 10 times of water gagings, and lixiviate 5h gets lixiviating solution and deposits; Add 8 times of water gagings again, temperature 70 C ~ 80 DEG C lixiviate 3h, merges twice decoction liquor, uses 100 mesh screen;

2. concentrate drying: filtrate is inserted in vacuum concentration pot, setting vacuum 97kPa, temperature 55 DEG C ~ 70 DEG C, be condensed into concentrated solution, concentrated solution is 25% of Chinese medicinal components, then by concentrated solution through spraying dry, obtains lixiviate powder;

3. soft material processed: lixiviate powder 20% adds in kneader, then adds cane sugar powder, dextrin, is modulated to soft material medicine with the ethanol of content 50% and sticks together;

4. granulate: adopt granulation machine to produce wet shape granule;

5. dry: wet shape granule is inserted dehydrate in 60 DEG C of pneumatic driers;

6. granulate: by dried granule after 1 10 mesh sieve granulate, obtain dissolved granule;

7. sterilization packaging: after irradiating 2 ~ 3min under dissolved granule being inserted ultraviolet, every bag of 10g packs.

Embodiment 2

Chinese medicinal components: Radix Codonopsis 15%, Radix Salviae Miltiorrhizae 15%, Poria 15%, Radix Curcumae 15%, Radix Ophiopogonis 15%, Ramulus Cinnamomi 3%, Fructus Schisandrae Chinensis 8%, Radix Glycyrrhizae Preparata 8%, Fructus Amomi 5%, Typhonium flagelliforme (Lodd.) Blume 1%.

(2) preparation process is as follows:

1. lixiviate: by Chinese medicinal components remove impurity, pulverizing, inserts in interlayer pot for solvent extraction, and temperature 70 C ~ 80 DEG C add 10 times of water gagings, and lixiviate 5h gets lixiviating solution and deposits; Add 8 times of water gagings again, temperature 70 C ~ 80 DEG C lixiviate 3h, merges twice decoction liquor, uses 100 mesh screen;

2. concentrate drying: filtrate is inserted in vacuum concentration pot, setting vacuum 97kPa, temperature 55 DEG C ~ 70 DEG C, be condensed into concentrated solution, concentrated solution is 25% of Chinese medicinal components, then by concentrated solution through spraying dry, obtains lixiviate powder;

3. soft material processed: lixiviate powder 20% adds in kneader, then adds cane sugar powder, dextrin, is modulated to soft material medicine with the ethanol of content 50% and sticks together;

4. granulate: adopt granulation machine to produce wet shape granule;

5. dry: wet shape granule is inserted dehydrate in 60 DEG C of pneumatic driers;

6. granulate: by dried granule after 1 10 mesh sieve granulate, obtain dissolved granule;

7. sterilization packaging: after irradiating 2 ~ 3min under dissolved granule being inserted ultraviolet, every bag of 10g packs.

Embodiment 3

Chinese medicinal components: Radix Codonopsis 16%, Radix Salviae Miltiorrhizae 16%, Poria 14%, Radix Curcumae 14%, Radix Ophiopogonis 14%, Ramulus Cinnamomi 3%, Fructus Schisandrae Chinensis 8%, Radix Glycyrrhizae Preparata 8%, Fructus Amomi 6%, Typhonium flagelliforme (Lodd.) Blume 1%.

(2) preparation process is as follows:

1. lixiviate: by Chinese medicinal components remove impurity, pulverizing, inserts in interlayer pot for solvent extraction, and temperature 70 C ~ 80 DEG C add 10 times of water gagings, and lixiviate 5h gets lixiviating solution and deposits; Add 8 times of water gagings again, temperature 70 C ~ 80 DEG C lixiviate 3h, merges twice decoction liquor, uses 100 mesh screen;

2. concentrate drying: filtrate is inserted in vacuum concentration pot, setting vacuum 97kPa, temperature 55 DEG C ~ 70 DEG C, be condensed into concentrated solution, concentrated solution is 25% of Chinese medicinal components, then by concentrated solution through spraying dry, obtains lixiviate powder;

3. soft material processed: lixiviate powder 20% adds in kneader, then adds cane sugar powder, dextrin, is modulated to soft material medicine with the ethanol of content 50% and sticks together;

4. granulate: adopt granulation machine to produce wet shape granule;

5. dry: wet shape granule is inserted dehydrate in 60 DEG C of pneumatic driers;

6. granulate: by dried granule after 1 10 mesh sieve granulate, obtain dissolved granule;

7. sterilization packaging: after irradiating 2 ~ 3min under dissolved granule being inserted ultraviolet, every bag of 10g packs.

The above; embodiment is only be described the preferred embodiment of the present invention; not scope of the present invention is limited; under the prerequisite of spirit not departing from the technology of the present invention; the various distortion that this area engineers and technicians make technical scheme of the present invention and improvement, all should fall in protection domain that claims of the present invention determine.

Claims (2)

1. a Chinese medicinal granule electuary for Radix Codonopsis Radix Notoginseng Radix Ophiopogonis treatment coronary heart disease, is characterized in that: Chinese medicinal components is Radix Codonopsis 14% ~ 16%, Radix Salviae Miltiorrhizae 14% ~ 16%, Poria 14% ~ 16%, Radix Curcumae 14% ~ 16%, Radix Ophiopogonis 14% ~ 16%, Ramulus Cinnamomi 3% ~ 5%, Fructus Schisandrae Chinensis 8% ~ 10%, Radix Glycyrrhizae Preparata 8% ~ 10%, Fructus Amomi 5% ~ 7%, Typhonium flagelliforme (Lodd.) Blume 1% ~ 2%.

2. the Chinese medicinal granule electuary of a kind of Radix Codonopsis Radix Notoginseng Radix Ophiopogonis treatment coronary heart disease according to claim 1, is characterized in that: preparation process is as follows:

(1) lixiviate: by Chinese medicinal components remove impurity, pulverizing, inserts in interlayer pot for solvent extraction, and temperature 70 C ~ 80 DEG C add 10 times of water gagings, and lixiviate 5h gets lixiviating solution and deposits; Add 8 times of water gagings again, temperature 70 C ~ 80 DEG C lixiviate 3h, merges twice decoction liquor, uses 100 mesh screen;

(2) concentrate drying: filtrate is inserted in vacuum concentration pot, setting vacuum 97kPa, temperature 55 DEG C ~ 70 DEG C, be condensed into concentrated solution, concentrated solution is 25% of Chinese medicinal components, then by concentrated solution through spraying dry, obtains lixiviate powder;

(3) soft material processed: lixiviate powder 30% adds in kneader, then add cane sugar powder 10%, dextrin 10%, dried starch 50%, be modulated to soft material medicine with the ethanol of content 50% and stick together;

(4) granulate: adopt granulation machine to produce wet shape granule;

(5) dry: dehydrate in the pneumatic drier of wet shape granule being inserted 60 DEG C;

(6) granulate: by dried granule after 1 10 mesh sieve granulate, obtain dissolved granule;

(7) sterilization packaging: after irradiating 2 ~ 3min under dissolved granule being inserted ultraviolet, every bag of 10g packs.