CN101554471B - Traditional Chinese medicine preparation for treating myocardial infarction - Google Patents

Traditional Chinese medicine preparation for treating myocardial infarction Download PDF

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Publication number
CN101554471B
CN101554471B CN2009100744097A CN200910074409A CN101554471B CN 101554471 B CN101554471 B CN 101554471B CN 2009100744097 A CN2009100744097 A CN 2009100744097A CN 200910074409 A CN200910074409 A CN 200910074409A CN 101554471 B CN101554471 B CN 101554471B
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portions
blood
parts
radix
stasis
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CN2009100744097A
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CN101554471A (en
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靳恒利
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Hebei Weixiangfu Traditional Medicine Technology Development Co., Ltd.
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HEBEI WEIXIANGFU TRADITIONAL MEDICINE TECHNOLOGY DEVELOPMENT Co Ltd
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Abstract

The invention discloses a traditional Chinese medicine preparation for treating myocardial infarction. The preparation is prepared by the following raw materials according to proportion by weight: 30-60 portions of herb of dversifolious hemiphragma, 25-50 portions of salvia miltiorrhiza, 15-30 portions of radix curcumae, 15-30 portions of fructus trichosanthis, 10-20 portions of peach kernel, 15-30 portions of safflower, 10-20 portions of hemlock parsley, 20-40 portions of angelica, 15-30 portions of radix paeoniae rubrathe, 10-20 portions of dogwood fruit, 10-20 portions of cattail pollen and6-15 portions of honey-fried licorice root. The formula is reasonable in compatibility of all the medicines, takes the herb of diversifolious hemiphragma as the monarch drug to promote flow of qi andrelieve upset, invigorate blood circulation and remove blood stasis to dredging heart and blood vessels, and uses the salvia miltiorrhiza to enrich and invigorate blood, the radix curcumae to invigorate blood circulation and remove blood stasis, the fructus trichosanthis to well clear the thoracic and gastric dysphoria with smothery sensation and the peach kernel to also invigorate blood circulation and remove blood stasis as well as the stasis of heart and blood vessels. Besides, the safflower can invigorate blood circulation and remove blood stasis too; the hemlock parsley can enrich the blood and nourish yin; the angelica can supplement the loss of yin and blood; the radix paeoniae rubrathe can nourish blood and promote blood circulation; the dogwood fruit can tonify the liver and kidney, astringe vigor, keep up spirits and boost kidney and control nocturnal emission; the cattail pollen can remove stasis and resolve lump; and finally the honey-fried licorice root can access twelvemeridian musculatures and coordinate all the drugs.

Description

The Chinese medicine preparation of treatment myocardial infarction
Technical field
The present invention relates to a kind of Chinese medicine preparation, especially a kind of Chinese medicine preparation for the treatment of myocardial infarction.
Background technology
The main diseases of myocardial infarction is because of being coronary atherosclerosis, and idol is coronary thrombosis, inflammation, congenital malformation etc.Speckle causes luminal stenosis under coronary endometrium, and blood flow passes through slowly, deficiency myocardial blood supply, and side Zhi Xunhuan is not when fully setting up as yet, in case blood supply further sharply reduces or interrupts, make cardiac muscle seriously and enduringly acute ischemia reach more than 1 hour, myocardial infarction promptly takes place.In addition, on the coronary atherosclerosis basis, the arteria coronaria intimal thickening, speckle merges hemorrhage, ulcer calcification etc. makes the coarse injustice of tunica intima, platelet is easy to assemble, absorption, thereby makes in the tube chamber thrombosis or bring out arteria coronaria continuous vessel convulsion twin, finally causes total occlusion of coronary artery and myocardial infarction takes place.At present, medicine, Western medicine and the Chinese patent medicine of treatment myocardial infarction.Western medicine diminishes liver, though Chinese patent medicine is effective in cure, can not thoroughly cure myocardial infarction.
Summary of the invention
The technical problem to be solved in the present invention provides a kind of curative effect height, the Chinese medicine preparation of the treatment myocardial infarction that has no side effect.
For solving the problems of the technologies described above, the Chinese medicine preparation of treatment myocardial infarction of the present invention is made by the following weight proportion raw material: Herba hemipharagmatis heterophylli 30-60 part, Radix Salviae Miltiorrhizae 25-50 part, Radix Curcumae 15-30 part, Fructus Trichosanthis 15-30 part, Semen Persicae 10-20 part, Flos Carthami 15-30 part, Rhizoma Chuanxiong 10-20 part, Radix Angelicae Sinensis 20-40 part, Radix Paeoniae Rubra 15-30 part, Fructus Corni 10-20 part, Pollen Typhae 10-20 part, Radix Glycyrrhizae Preparata 6-15 part.
The further technical scheme of the present invention is: the preferred weight proportioning of described raw material is 30 parts of Herba hemipharagmatis heterophyllis, 25 parts of Radix Salviae Miltiorrhizaes, 15 parts of Radix Curcumaes, 15 parts of Fructus Trichosanthis, 10 parts in Semen Persicae, 15 parts on Flos Carthami, 10 parts of Rhizoma Chuanxiongs, 20 parts of Radix Angelicae Sinensis, 15 parts of Radix Paeoniae Rubra, 10 parts of Fructus Corni, 10 parts of Pollen Typhaes, 6 parts of Radix Glycyrrhizae Preparatas.
The technological progress that the present invention obtains is:
Herba hemipharagmatis heterophylli: nature and flavor, little sweet temperature; Function cures mainly: promoting QI circulation for relieving depression, and promoting the circulation of QI to relieve pain, the spleen reinforcing stomach function regulating, the Guang abdominal distention and pain, dispelling, collateral-activating, antalgic, dredge the meridian passage, blood stasis removing stagnates, and regulates the flow of vital energy, and pain relieving is eliminated the phlegm, expelling wind and removing dampness, lumbago due to pathogenic wind-dampness, neurasthenia, tetanus.
Radix Salviae Miltiorrhizae: nature and flavor, sweet being slightly cold; Function cures mainly: blood circulation promoting and blood stasis dispelling, and removing heat from blood ends tired, and tranquilizing the mind is arranged dense pain relieving, and the heat in blood stasis of blood stagnates, menoxenia, dysmenorrhea, amenorrhea costalgia, abdominal part swelling, limb muscle pain.
Radix Curcumae: nature and flavor are arduous cold, and function cures mainly: blood circulation promoting and blood stasis dispelling, and promoting QI circulation for relieving depression, the qi depression to blood stasis abdominal pain is painful, costalgia uncomfortable in chest, the distension vicarious menstruation, hematemesis and epistaxis, stagnation of QI expectorant covers, damp and hot condensing.
Fructus Trichosanthis: nature and flavor, sweet cold; Function cures mainly: removing heat-phlegm, moisten dryness and relieve cough, and the promoting the circulation of QI relieving stuffiness of the chest by dispersing aggregation of pathogens, dryness of the lung impairment of body fluid, cough expectorant is thick, coughs up and tells not freely, breathe, the fullness in the chest unhappiness, the thoracic obstruction, pained, pyretic toxicity pent-up, acute mastitis.
Semen Persicae: nature and flavor, bitter sweet flat, function cures mainly: blood stasis removing and clots absorbing, the intestine moistening blood stasis congelation, amenorrhea, dysmenorrhea, lump, stomachache, the costalgia acute appendicitis, blood is dry not to moisten constipation.
Flos Carthami: nature and flavor, Xin Wen; Function cures mainly, promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing, blood stasis congelation, amenorrhea bellyache, arthralgia, postnatal blood stasis.
Rhizoma Chuanxiong: nature and flavor, Xin Wen; Function cures mainly, blood-activating and qi-promoting, and the wind pain relieving of loosing, the liver stasis of blood stagnation of QI, the costa sternales pain, migraine, rheumatic Bi syndrome, stagnation of QI and blood, fever with chills, arthralgia, the muscle arteries and veins is arrested curved.
Radix Angelicae Sinensis: nature and flavor, sweet arduous temperature; Function cures mainly, tonifying blood and regulating menstruation, and promoting blood circulation and stopping pain is moisturized laxation, heart-liver blood deficiency, yellowish complexion withers, and is dizzy dizzy, the resistance of blood stasis network, rheumatic arthralgia, damage, pain, carbuncle.
Radix Paeoniae Rubra: nature and flavor, bitter being slightly cold; Function cures mainly, and heat clearing and blood cooling overstocks blood, detumescence, and the blood stasis retardance, abdominal pain during menstruation, the amenorrhea costalgia, the stasis of blood knot heat in blood stasis of blood stagnates, and heat is gone into nutrient blood, macule, carbuncle sore tumefacting virus.
Fructus Corni: nature and flavor, sour and astringent tepor, function cures mainly, nourishing liver and replenishing blood, the kidney invigorating arresting seminal emission, arresting sweating takes off admittedly, Liver and kidney two void, lumbago, sexual impotence, seminal emission, dizzy, tinnitus, deafness, the menstruation polyuria is frequently.
Pollen Typhae: nature and flavor are sweet flat; Function cures mainly, and the blood stasis knot stagnates, the amenorrhea dysmenorrhea, and the postnatal blood stasis abdomen is painful, the heat in blood aspirations and conduct, hematemesis and epistaxis is had blood in stool.
Radix Glycyrrhizae Preparata: nature and flavor, sweet flat, process the back tepor; Function cures mainly, current ten ground warps, and invigorating the spleen and replenishing QI, lung moistening is eliminated the phlegm, heat-clearing and toxic substances removing, profit and all medicines, deficiency of the spleen and lung is had loose bowels, raw meat pain, stomachache, carbuncle, skin infection.
The present invention is according to inventor's clinical experience for many years, experiment repeatedly, this medicine has very significant curative effect to prevention and treatment acute and chronic myocardial infarction, myocardial infarction causes the serious and persistent acute ischemia of corresponding cardiac muscle and the local necrosis that causes, be more serious serious symptom type, primary disease belongs to Chinese medicine categories such as " angina pectoriss ".
Tendency, part patient refreshing tired general power occurs in premorbid in a few days to several weeks, pareordia is to the chest discomfort, cardiopalmus when movable, and gas is striven fidgety, the symptom of Chu Xianing is similar to angina pectoris at first, but degree is more violent, is insufferable squeezing more, suffocate, in addition dying, and feeling has dripping sweat, dysphoria, heating, tachycardia, leukocyte raises, and erythrocyte sedimentation rate speeds.
In arrhythmia, the especially onset three days, with stopping up property ectopic cardiac rhythm, mainly show as left ventricular insufficiency, right ventricle failure takes place in right ventricle heart infarction person at the very start.
The present invention prescription, all medicine compatibilities are reasonable, are the monarch drug promoting QI circulation for relieving depression with the Herba hemipharagmatis heterophylli, and blood circulation promoting and blood stasis dispelling mediation cardiovascular is joined Radix Salviae Miltiorrhizae and is enriched blood and invigorate blood circulation, the Radix Curcumae blood circulation promoting and blood stasis dispelling, the dysphoria with smothery sensation of the kind clear breast stomach of Fructus Trichosanthis, the Semen Persicae blood circulation promoting and blood stasis dispelling can go cardiovascular stasis, Flos Carthami, blood circulation promoting and blood stasis dispelling, Rhizoma Chuanxiong, the tonifying YIN of enriching blood, the loss of Radix Angelicae Sinensis energy nourishing YIN blood, Radix Paeoniae Rubra, nourshing blood and promoting blood circulation, Fructus Corni, liver and kidney tonifying, convergence vigour is cheered up the kidney tonifying controlling nocturnal emission with astringent drugs, Pollen Typhae, eliminating stasis and resolving masses, Radix Glycyrrhizae Preparata leads to 12 warps, coordinating the actions of various ingredients in a prescription.
Make a general survey of full side, play altogether, preventing and treating myocardial infarction has definite curative effect.
Toxicity test: the medicine of the present invention being treated myocardial infarction is given 100 mice lavage administration 30g medicinal liquid/kg, 50 times of quite clinical human body consumption, the viewing duration animal diet followed is normal, do not see that the animal generation is dead, animal activity reduces to some extent after irritating stomach, but animal survival is in good condition, recovers normal behind the 8h, illustrates that it is safe that said preparation is taken.
The inventor is to 300 routine case clinical observations, male 200 people wherein, women 100 people, 35 years old-75 years old age, course of disease 3-20, by taking medicine of the present invention, general medication 3-4 course of treatment, 291 people healing, it is effective that cure rate reaches 97%, 300 people, and effective percentage is 100%.
Model case: 1, grandson, woman, 45 years old, the cadre.Excessive thinking, excited, insomnia forgetfulness, chest distress often, shortness of breath and palpitation, myocardial oxygen consumption increases suddenly, and the weak property of cardiovascular is gone down, and through taking capsule of the present invention two courses of treatment on the 60th, symptom subtracts greatly, obeys two courses of treatment again, the symptom recovery from illness.
2, Wang, woman, 37 years old, the workman.Suffer from pareordia to the chest discomfort, activity cardiopalmus, out of breath, dysphoria, sweating is dripping, and flushing yellow fur rolling pulse is through taking three courses of treatment of capsule of the present invention, transference cure.
3, high mountain, man, 61 years old, cadre, suffer from hypertension, arrhythmia, tachycardia, frequent nauseating, vomiting, epigastrium distending pain, dysphoria, front severe pain, is felt suffocated at cardiopalmus, because the state of an illness is anxious, takes herb liquid of the present invention earlier, the state of an illness was basicly stable in 15 days, three courses of treatment of clothes capsule of the present invention are continued in the back, and transference cure is not sent out with anti-1 year disease.
4, Luo, woman, 56 years old, retired cadre.Suffer from coronary heart disease, long-term arrhythmia, deficiency myocardial blood supply, heart arter is atherosis, and is uncomfortable in chest, and night, sleep was often had nightmares, and shortness of breath and palpitation is felt oppressed, and through obeying 2 courses of treatment of capsule of the present invention, disease all disappears.
5, Wang, man 61 years old.Cerebral infarction took place before 1 year, the cold of numbness of hand foot, secondary is given birth to uncomfortable in chest, angina pectoris, insomnia, unhappiness, loss of appetite, dysphoria, excited, through three courses of treatment of clothes capsule of the present invention, symptom disappears substantially.
6, China certain, man 41 years old, the workman.Suffer from hypertension, myocardial infarction, pareordia uncomfortable in chest often is to the back backache, nausea and vomiting, arrhythmia, hypomnesis, tinnitus, deafness, dysphoria with feverish sensation in the chest palms and soles, through 3 courses of treatment of clothes capsule of the present invention, symptom subtracts greatly, but uncomfortable in chest in addition, takes a course of treatment again, transference cure.
The specific embodiment
Embodiment 1, and the Chinese medicine preparation of treatment myocardial infarction of the present invention prepares by following heavy amount component: Herba hemipharagmatis heterophylli 30g, Radix Salviae Miltiorrhizae 25g, Radix Curcumae 15g, Fructus Trichosanthis 15g, Semen Persicae 10g, Flos Carthami 15g, Rhizoma Chuanxiong 10g, Radix Angelicae Sinensis 20g, Radix Paeoniae Rubra 15g, Fructus Corni 10g, Pollen Typhae 10g, Radix Glycyrrhizae Preparata 6g.
Preparation method: each raw material is carried out strictness screen, purify, dry, take by weighing, produce all types of pharmaceutical preparatioies by regular pharmaceutical technology flow process then, as make oral Chinese medicine liquid, concentrated granular electuary, tablet or capsule.
Instructions of taking: after the raw material of above-mentioned weight is made the Chinese medicine preparation of this treatment myocardial infarction, took at twice in one day, 30 is a course of treatment.
Embodiment 2-5: adopt the feedstock production of following weight, preparation method and taking with embodiment 1.
Embodiment 2 Embodiment 3 Embodiment 4 Embodiment 5
Herba hemipharagmatis heterophylli (g) 30 60 40 50
Radix Salviae Miltiorrhizae (g) 40 25 35 28
Radix Curcumae (g) 15 30 20 16
Fructus Trichosanthis (g) 30 15 20 28
Semen Persicae (g) 10 20 15 18
Flos Carthami (g) 30 15 20 14
Rhizoma Chuanxiong (g) 10 20 15 12
Radix Angelicae Sinensis (g) 40 20 30 35
Radix Paeoniae Rubra (g) 15 30 20 25
Fructus Corni (g) 20 10 15 16
Pollen Typhae (g) 10 20 12 17
Radix Glycyrrhizae Preparata (g) 15 6 13 8

Claims (2)

1. treat the Chinese medicine preparation of myocardial infarction, it is characterized in that, make: Herba hemipharagmatis heterophylli 30-60 part, Radix Salviae Miltiorrhizae 25-50 part, Radix Curcumae 15-30 part, Fructus Trichosanthis 15-30 part, Semen Persicae 10-20 part, Flos Carthami 15-30 part, Rhizoma Chuanxiong 10-20 part, Radix Angelicae Sinensis 20-40 part, Radix Paeoniae Rubra 15-30 part, Fructus Corni 10-20 part, Pollen Typhae 10-20 part, Radix Glycyrrhizae Preparata 6-15 part by the following weight proportion raw material.
2. the Chinese medicine preparation of treatment myocardial infarction according to claim 1, it is characterized in that the preferred weight proportioning of above-mentioned raw materials is: 30 parts of Herba hemipharagmatis heterophyllis, 25 parts of Radix Salviae Miltiorrhizaes, 15 parts of Radix Curcumaes, 15 parts of Fructus Trichosanthis, 10 parts in Semen Persicae, 15 parts on Flos Carthami, 10 parts of Rhizoma Chuanxiongs, 20 parts of Radix Angelicae Sinensis, 15 parts of Radix Paeoniae Rubra, 10 parts of Fructus Corni, 10 parts of Pollen Typhaes, 6 parts of Radix Glycyrrhizae Preparatas.
CN2009100744097A 2009-05-21 2009-05-21 Traditional Chinese medicine preparation for treating myocardial infarction Expired - Fee Related CN101554471B (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109908301A (en) * 2019-04-09 2019-06-21 河北鹿天力科技有限公司 A kind of Chinese materia medica preparation for treating myocardial infarction

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104667203B (en) * 2015-03-30 2018-02-23 陈桂启 A kind of medicine for treating coronary heart disease
CN104997841A (en) * 2015-08-24 2015-10-28 李会明 Chinese herbal medicine powder for treating thrombotic heart disease

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109908301A (en) * 2019-04-09 2019-06-21 河北鹿天力科技有限公司 A kind of Chinese materia medica preparation for treating myocardial infarction

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