CN104667203B - A kind of medicine for treating coronary heart disease - Google Patents
A kind of medicine for treating coronary heart disease Download PDFInfo
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Abstract
The invention discloses a kind of medicine for treating coronary heart disease, belong to technical field of traditional Chinese medicines.The medicine is made up of the bulk drug of following parts by weight：10 20 parts of Radix Angelicae Sinensis, 5 15 parts of Ligusticum wallichii, 6 10 parts of perilla seed, 20 30 parts of the radix paeoniae rubrathe, 10 20 parts of safflower, 15 25 parts of corydalis tuber, 10 20 parts of santal, 48 parts of root tuber of aromatic turmeric, 26 parts of dragon's blood, 10 20 parts of kaempferia galamga, 6 12 parts of asarum, 8 16 parts of peach kernel, 10 20 parts of cattail pollen, 15 25 parts of radix cyathulae, 10 16 parts of curcuma zedoary, 20 30 parts of fig, 48 parts of semen brassicae, 8 12 parts of radix scrophulariae, 38 parts of Asian puccoon, 10 15 parts of rattletop, 15 25 parts of Semen Cuscutae, 10 20 parts of radix polygonati officinalis, 20 30 parts of saline cistanche.Medicine of the present invention is formulated by pure Chinese medicine, and scientific formulation is reasonable, has curative effect height, quick, the recurrence after healing can be avoided, cost is low, the characteristics of having no side effect safely.
Description
Technical field
The present invention relates to a kind of medicine for treating coronary heart disease, belong to technical field of traditional Chinese medicines.
Background technology
Coronary heart disease is one kind by organic (the atherosclerosis or dynamic property vasopasm) stenosis or occlusion of coronary artery
Caused myocardial ischemia-anoxemia (angina pectoris) or the heart disease of myocardial necrosis (miocardial infarction), also known as ischemic heart disease.With
The improvement of people's living standards, the change of habits and customs, and the progress faster of aging society, the incidence of disease of coronary heart disease is increasingly
Increase, the hazards for influence coronary heart disease generation, developing are increasing, seriously jeopardize the health of the mankind.Statistics are shown, are preced with
The illness rate of worry is usually that male is higher than women, and China in 2011 dies from coronary heart disease number and reaches 3,000,000, and patients with coronary heart disease is total
Number reaches 2.7 hundred million, wherein the patient of 70 years old accounts for more than 60%, coronary heart disease is up to 80% to the lethality of the elderly.Recently as
The trend of rejuvenation is gradually presented in people life style and the change of work rhythm, the incidence of disease of coronary heart disease, in 30-35 year crowd
The incidence of disease of middle patients with coronary heart disease accounts for the 5% of whole incidence of coronary heart disease numbers.Particularly urgent thus is seemed to the Therapy study of coronary heart disease
Cut.
Two methods of the doctor trained in Western medicine for the treatment of key agents treatment in to(for) coronary heart disease and operative treatment at present, but Western medicine side effect
Greatly, and cure the symptoms, not the disease；Costly and operative treatment risk is big, the pain that patient bears is big.Coronary heart disease is in traditional Chinese medical science category " chest
Numbness ", the category of " pained ", it can not only improve the symptom of patient using Coronary Heart Diseases Treated with TCM and can largely improve
The pathology damage of patient, show its unique advantage in coronary heart disease treatment.Miscellaneous treatment on market today be present
The Chinese medicine of coronary heart disease, but their therapeutic effect is not universal high, and the course for the treatment of is longer, the defects of easily recurrence after healing.
The content of the invention
For problems of the prior art, the invention provides a kind of medicine for treating coronary heart disease.The medicine is by pure
Traditional Chinese medicine forms, and scientific formulation is reasonable, has curative effect height, quick, the recurrence after healing can be avoided, cost is low, has no side effect safely
Feature.
The present invention uses following technical scheme：
A kind of medicine for treating coronary heart disease, it is characterised in that it is made up of the bulk drug of following parts by weight：Radix Angelicae Sinensis 10-
20 parts, Ligusticum wallichii 5-15 parts, perilla seed 6-10 parts, radix paeoniae rubrathe 20-30 parts, safflower 10-20 parts, corydalis tuber 15-25 parts, santal 10-20
Part, root tuber of aromatic turmeric 4-8 parts, dragon's blood 2-6 parts, kaempferia galamga 10-20 parts, asarum 6-12 parts, peach kernel 8-16 parts, cattail pollen 10-20 parts, radix cyathulae
15-25 parts, curcuma zedoary 10-16 parts, fig 20-30 parts, semen brassicae 4-8 parts, radix scrophulariae 8-12 parts, Asian puccoon 3-8 parts, rattletop 10-15
Part, Semen Cuscutae 15-25 parts, radix polygonati officinalis 10-20 parts, saline cistanche 20-30 parts.
Preferably, the medicine of above-mentioned treatment coronary heart disease is made up of the bulk drug of following parts by weight：15 parts of Radix Angelicae Sinensis, Ligusticum wallichii 10
Part, 8 parts of perilla seed, 25 parts of the radix paeoniae rubrathe, 15 parts of safflower, 20 parts of corydalis tuber, 15 parts of santal, 6 parts of root tuber of aromatic turmeric, 5 parts of dragon's blood, 15 parts of kaempferia galamga,
8 parts of asarum, 12 parts of peach kernel, 15 parts of cattail pollen, 20 parts of radix cyathulae, 14 parts of curcuma zedoary, 25 parts of fig, 6 parts of semen brassicae, 10 parts of radix scrophulariae,
6 parts of Asian puccoon, 12 parts of rattletop, 20 parts of Semen Cuscutae, 15 parts of radix polygonati officinalis, 25 parts of saline cistanche.
Medicine of the present invention can use the conventional method of Chinese medicine preparation, prepare piece agent, pill, capsule, particle
Any of agent, oral liquid or decoction.
The preferred dosage form of the present invention is capsule.Above medicinal material is matched somebody with somebody by measuring, and it is powder mistake afterwards to crush the medicine
100 mesh sieves, mix sterilization and load capsule, each capsule is got product by 0.4 gram of dress.
The usage and dosage of the present invention：Orally, three times a day, 3 tablets each time, take within 1 hour after meal, be within 10 days 1 course for the treatment of, one
As 1 course for the treatment of can take effect, the 3-4 course for the treatment of can cure, and patient with severe symptoms needs the 5-6 course for the treatment of.
Medicine pharmacological action of the present invention is as follows：
Radix Angelicae Sinensis：It is sweet, pungent, warm；Return liver, the heart, the spleen channel；With benefiting blood and regulating blood circulation, menstruction regulating and pain relieving is moisturize laxation, anticancer, anti-ageing anti-
Always, the effect of being immunized.Ligusticum wallichii：It is pungent, temperature；Enter liver, gallbladder channel；With promote breath and open depression, method wind-dryness is wet, the effect of promoting blood circulation and stopping pain.Purple perilla
Son：It is pungent, temperature；Return lung passes through；It is relieving cough and asthma with sending down abnormally ascending dissolving phlegm, the effect of ease constipation.The radix paeoniae rubrathe：Hardship, it is slightly cold；Return liver warp；There is heat-clearing cool
Blood, the effect of promoting blood circulation.Safflower：It is pungent, temperature；The thoughts of returning home, Liver Channel；With invigorate blood circulation, the effect of blood stasis removing analgesic.Corydalis tuber：Pungent,
Hardship, temperature；Return liver, the spleen channel；With promoting blood circulation, promoting the circulation of qi, the effect of analgesic.Santal：It is pungent, temperature；Returns spleen, stomach, the heart, lung channel；With promoting the circulation of qi
Middle benefit gas, the effect of relieving pain of whetting the appetite.Root tuber of aromatic turmeric：It is pungent, bitter, tremble with fear；Return liver, the heart, lung channel；With promoting blood circulation and stopping pain, promoting qi circulation and removing obstruction in the collateral, clear away heart-fire cool
Blood, the effect of normalizing gallbladder to cure jaundice.Dragon's blood：It is sweet, salty, put down；The thoughts of returning home, Liver Channel；With promoting blood circulation analgesic therapy, removing blood stasis and hemostasis, the work(of expelling pus and promoting granulation
Effect.Kaempferia galamga：It is pungent, temperature；Returns spleen, stomach；With warming middle-JIAO for eliminating dampness, the effect of promoting qi circulation and relieving pain.Asarum：It is pungent, temperature；The thoughts of returning home, lung, kidney channel；
With relieving exterior syndrome and dispelling cold, wind-expelling pain-stopping is sensible, the effect of Wenfei of drink.Peach kernel：Bitter, sweet, flat；The thoughts of returning home, liver, large intestine channel；With work
Blood and dissolving stasis, relax bowel, it is relieving cough and asthma the effect of.Cattail pollen：It is sweet, put down；Return liver, pericardium channel；With hemostasis, stagnation resolvation, treating stranguria work(
Effect.Radix cyathulae：Sweet, slight bitter, put down；Return liver and kidney channel；It is easing joint movement with dispelling stasis of blood and stimulating the menstrual flow, the effect of inducing diuresis for treating strangurtia.Curcuma zedoary：Pungent,
Hardship, temperature；Return liver, the spleen channel；With blood-breaking, the effect of Xiao Ji Zhi Tong.Fig：It is flat, it is sweet；Returns spleen passes through；With strengthening the spleen and replenishing qi,
Subdhing swelling and detoxicating, nourish ease constipation the effect of.Semen brassicae：It is odorless, it is pungent, peppery；Enter meridian of Hand-TAI YIN；With warm lung slit phlegm profit gas, dissipating bind is led to
The effect of network relieves pain.Radix scrophulariae：It is sweet, bitter, salty, it is slightly cold；Returns spleen, stomach, kidney channel；Clearing heat and cooling blood, nourishing Yin and falling fire, the work(of detoxicating and resolving a mass
Effect.Asian puccoon：It is sweet, salty, tremble with fear；The thoughts of returning home, Liver Channel；With cooling and activating blood, the effect of promoting eruption of detoxifying.Rattletop：It is pungent, sweet, it is slightly cold；Return lung,
Spleen, large intestine, stomach；Promoting eruption is delivered, it is clearing heat and detoxicating, the effect of yang invigorating.Semen Cuscutae：Xin Gan, put down；Enter liver and kidney channel；Nourish liver
Kidney, astringent sperm contracting urine is antiabortive, the effect of improving eyesight antidiarrheal.Radix polygonati officinalis：It is sweet, put down；Enter lung, stomach；With nourishing yin to moisten dryness, it is promoted the production of body fluid to quench thirst
Effect.Saline cistanche：It is sweet, salty, warm-natured；Return kidney, large intestine channel；With kidney-replenishing, benefiting essence-blood, the effect of ease constipation road.
The beneficial effects of the invention are as follows：Pharmaceutical formulation of the present invention is scientific and reasonable, and its drug effect has synergy, has promoting blood circulation
The effect of stagnation resolvation, promoting qi circulation and relieving pain, tonifying middle-Jiao and Qi, warming kidney and enhancing body, it can effectively adjust cardiac function.Demonstrate,proved through clinical application for many years
Bright, medicine of the invention is evident in efficacy to various coronary heart disease, and the property of medicine is gentle, and effective rapid, cure rate is high, does not recur, safe nothing
Toxic side effect.
Embodiment
With reference to specific embodiment, the present invention is described in further detail.
Embodiment 1
A kind of medicine for treating coronary heart disease, it is made up of the bulk drug of following weight：Radix Angelicae Sinensis 10g, Ligusticum wallichii 5g, perilla seed
6g, radix paeoniae rubrathe 20g, safflower 10g, corydalis tuber 15g, santal 10g, root tuber of aromatic turmeric 4g, dragon's blood 2g, kaempferia galamga 10g, asarum 6g, peach kernel 8g, cattail pollen
10g, radix cyathulae 15g, curcuma zedoary 10g, fig 20g, semen brassicae 4g, radix scrophulariae 8g, Asian puccoon 3g, rattletop 10g, Semen Cuscutae 15g, radix polygonati officinalis
10g, saline cistanche 20g.
Above-mentioned medicinal material is matched somebody with somebody by measuring, the medicine is crushed cross 100 mesh sieves for powder afterwards, sterilization is mixed and loads glue
Capsule, each capsule are got product by 0.4 gram of dress.
Embodiment 2
A kind of medicine for treating coronary heart disease, it is made up of the bulk drug of following weight：Radix Angelicae Sinensis 15g, Ligusticum wallichii 10g, purple perilla
Sub- 8g, radix paeoniae rubrathe 25g, safflower 15g, corydalis tuber 20g, santal 15g, root tuber of aromatic turmeric 6g, dragon's blood 5g, kaempferia galamga 15g, asarum 8g, peach kernel 12g,
Cattail pollen 15g, radix cyathulae 20g, curcuma zedoary 14g, fig 25g, semen brassicae 6g, radix scrophulariae 10g, Asian puccoon 6g, rattletop 12g, Semen Cuscutae
20g, radix polygonati officinalis 15g, saline cistanche 25g.
Above-mentioned medicinal material is matched somebody with somebody by measuring, the medicine is crushed cross 100 mesh sieves for powder afterwards, sterilization is mixed and loads glue
Capsule, each capsule are got product by 0.4 gram of dress.
Embodiment 3
A kind of medicine for treating coronary heart disease, it is made up of the bulk drug of following weight：Radix Angelicae Sinensis 20g, Ligusticum wallichii 15g, purple perilla
Sub- 10g, radix paeoniae rubrathe 30g, safflower 20g, corydalis tuber 25g, santal 20g, root tuber of aromatic turmeric 8g, dragon's blood 6g, kaempferia galamga 20g, asarum 12g, peach kernel
16g, cattail pollen 20g, radix cyathulae 25g, curcuma zedoary 16g, fig 30g, semen brassicae 8g, radix scrophulariae 12g, Asian puccoon 8g, rattletop 15g, Tu silk
Sub- 25g, radix polygonati officinalis 20g, saline cistanche 30g.
Above-mentioned medicinal material is matched somebody with somebody by measuring, the medicine is crushed cross 100 mesh sieves for powder afterwards, sterilization is mixed and loads glue
Capsule, each capsule are got product by 0.4 gram of dress.
Embodiment 4
A kind of medicine for treating coronary heart disease, it is made up of the bulk drug of following weight：Radix Angelicae Sinensis 14g, Ligusticum wallichii 8g, perilla seed
9g, radix paeoniae rubrathe 28g, safflower 12g, corydalis tuber 22g, santal 16g, root tuber of aromatic turmeric 5g, dragon's blood 5g, kaempferia galamga 15g, asarum 10g, peach kernel 14g, Pu
Yellow 18g, radix cyathulae 18g, curcuma zedoary 14g, fig 28g, semen brassicae 7g, radix scrophulariae 12g, Asian puccoon 6g, rattletop 14g, Semen Cuscutae 18g,
Radix polygonati officinalis 16g, saline cistanche 22g.
Above-mentioned medicinal material is matched somebody with somebody by measuring, the medicine is crushed cross 100 mesh sieves for powder afterwards, sterilization is mixed and loads glue
Capsule, each capsule are got product by 0.4 gram of dress.
Clinical practice example
1. clinical data：Randomly select outpatient service and accept patients with coronary heart disease 660 for medical treatment, be divided into Liang Zuji treatment groups and control
Group, there was no significant difference for clinical data between two groups, and two groups of ages, sex, the course of disease, complication etc. are statistically analyzed, and difference is equal
Without significant（P>0. 05）, there is comparativity.
2. diagnostic criteria：According to angina pectoris, the clinical medical history of miocardial infarction or electrocardiogram, open in-heart operation under pulsating, fortune
Dynamic load electrocardiogram, Nuclear Cardiac Imaging and coronarography can be made a definite diagnosis.
3. treatment method：Treatment group uses medicine made from the embodiment of the present invention 2, orally, three times a day, and 3 tablets each time, meal
Take within 1 hour afterwards, 10 days are 1 course for the treatment of, and general 1 course for the treatment of can take effect, and the 3-4 course for the treatment of can cure, and patient with severe symptoms needs 5-6 treatment
Journey.Control group is treated using conventional western medicine, such as ISDN, beta-blocker, aspirin, Verapamil, pungent cuts down him
The drug therapies such as spit of fland, continuous treatment observe curative effect after 60 days.
4. curative effect determinate standard：
Cure：Normal ECG, clinical symptoms all disappear, and follow-up more than 1 year is without recurrence；
Take a turn for the better：Electrocardiogram is clearly better, and clinical symptoms substantially mitigate or disappeared more than half；
It is invalid：Electrocardiogram is without significant change, and clinical symptoms are without improvement.
5. treatment results：It is shown in Table 1.
The clinical treatment outcome of table 1
| Group | Case load | Cure n | Improvement n | Invalid n | Total effective rate % |
| Treatment group | 330 | 286 | 42 | 2 | 99.4% |
| Control group | 330 | 195 | 55 | 80 | 75.8% |
As can be seen from the above results, the treatment of medicine of the invention to coronary heart disease has treatment more more preferable than general Western medicine
Effect, it is treated total effective rate and is up to 99.4%, is that one kind treats coronary heart disease good medicine, good fortune is brought to vast middle-old aged coronary heart disease patient
Sound.
Model case
Case 1：Money, man, 60 years old, uncomfortable in chest, profuse sweating, Nausea and vomiting and when and with after breastbone squeezing property pain, once in a while
There is angina pectoris, be diagnosed as coronary heart disease.Substantially mitigated using clinical symptoms after 1 course for the treatment of of medicine of the embodiment of the present invention 2, the heart twists
Pain breaking-out interval time is progressively longer, it is rear continue 2 courses for the treatment of of after treatment after, clinical symptoms all disappear, and follow-up 2 years is not multiple
Hair.
Case 2：What so-and-so, man, 48 years old, repeatedly pectoralgia have a surplus within 3 years, can have difficulty in breathing during exacerbation, palpitaition, companioned with headache is disliked
The heart, tentative diagnosis are coronary heart disease.After 3 courses for the treatment of of medicine using the embodiment of the present invention 3, patient clinical symptom all disappears,
Follow-up is not recurred for 1 year.
Case 3：Cai so-and-so, female, 58 years old, paroxysmal pectoralgia was more than 2 years, breaking-out more than 10 times, and with nausea and vomiting, the heart daily
Flurried symptom uncomfortable in chest, clinical diagnosis is coronary heart disease.After 4 courses for the treatment of of medicine of the embodiment of the present invention 1, clinical symptoms all disappear
Lose, follow-up a year and a half does not recur.
Case 4：Guo so-and-so, man, 72 years old, suffer from coronary heart disease and have a surplus for 6 years, frequent uncomfortable in chest, shortness of breath is dizzy, nausea and with when
And angina pectoris sense, later angina pectoris attacks are frequent, constriction uncomfortable in chest is increasingly severe, carrys out here treatment then, using of the invention real
After 2 courses for the treatment of of medicine for applying example 4, clinical symptom disappearance is more than half, and patient fully recovers after continuing to strengthen 2 courses for the treatment of of treatment, and follow-up 3 years is not
Recurrence.
Claims (1)
1. a kind of medicine for treating coronary heart disease, it is characterised in that it is made up of the bulk drug of following parts by weight：15 parts of Radix Angelicae Sinensis,
10 parts of Ligusticum wallichii, 8 parts of perilla seed, 25 parts of the radix paeoniae rubrathe, 15 parts of safflower, 20 parts of corydalis tuber, 15 parts of santal, 6 parts of root tuber of aromatic turmeric, 5 parts of dragon's blood, kaempferia galamga
15 parts, 8 parts of asarum, 12 parts of peach kernel, 15 parts of cattail pollen, 20 parts of radix cyathulae, 14 parts of curcuma zedoary, 25 parts of fig, 6 parts of semen brassicae, radix scrophulariae
10 parts, 6 parts of Asian puccoon, 12 parts of rattletop, 20 parts of Semen Cuscutae, 15 parts of radix polygonati officinalis, 25 parts of saline cistanche.
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101554471A (en) * | 2009-05-21 | 2009-10-14 | 河北金大地房地产开发有限公司 | Traditional Chinese medicine preparation for treating myocardial infarction |
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| CN101554471A (en) * | 2009-05-21 | 2009-10-14 | 河北金大地房地产开发有限公司 | Traditional Chinese medicine preparation for treating myocardial infarction |
Non-Patent Citations (2)
| Title |
|---|
| HPLC法测定桃红丸中羟基红花黄色素A的含量;孙成宏等;《中国药师》;20121231;第15卷(第12期);第1808-1809页，尤其是第1808页左栏第1段 * |
| 桃红四物汤加减治疗冠心病68例疗效观察;刘杏鑫;《山西中医》;19941231;第10卷(第5期);第13-14页，尤其是第13页左栏最后1段、右栏倒数第3段 * |
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Inventor after: Chen Guiqi Inventor before: Jiang Jinli Inventor before: Liu Junfang Inventor before: Xing Yang Inventor before: Xu Qian Inventor before: Zhuang Xuna Inventor before: Wang Yuan |
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