CN102366469A - Drug for treating leucoderma - Google Patents

Drug for treating leucoderma Download PDF

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Publication number
CN102366469A
CN102366469A CN2011102586625A CN201110258662A CN102366469A CN 102366469 A CN102366469 A CN 102366469A CN 2011102586625 A CN2011102586625 A CN 2011102586625A CN 201110258662 A CN201110258662 A CN 201110258662A CN 102366469 A CN102366469 A CN 102366469A
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parts
radix
medicine
blood
herba
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CN2011102586625A
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谢培德
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Chengdu LVDI Technology Co Ltd
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Chengdu LVDI Technology Co Ltd
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Abstract

The invention provides a drug for treating leucoderma. The drug comprises the following components in parts by weight: 25-35 parts of dried rehmannia root, 12-18 parts of red peony, 12-18 parts of radix salviae miltiorrhizae, 9-15 parts of angelica, 9-15 parts of hemlock parsley, 8-12 parts of peach kernel, 8-12 parts of skullcap, 7-11 parts of burnet, 7-11 parts of nepeta, 7-11 parts of ledebouriella seseloides, 7-11 parts of herba siegesbeckiae, 9-15 parts of cortex dictamni, 9-15 parts of kochia scoparia, 7-11 parts of black snake and 2-4 parts of raw licorice. Compared with the prior art, the drug provided by the invention can treat the internal disease evil of leucoderma according to the syndrome difference, has the advantages of rapid acting, low cost, no toxic or side effect and obvious effect, and can treat both the principal and secondary aspects of the disease.

Description

The leukodermic medicine of a kind of treatment
Technical field
The present invention relates to a kind of Chinese medicine, more particularly, relate to the leukodermic medicine of a kind of treatment.
Background technology
Vitiligo is a kind of pigmented dermatosis of common pilosity.It is characteristic that this disease forms white macula with local or general property depigmentation, is a kind of acquired limitation or general property depigmentation of skin, is the common skin diseases of an influence beauty treatment, is prone to diagnosis, and treatment is difficult.Vitiligo is that posteriority is lost the limitation white patch that takes place because of skin pigment takes off, and makes local skin be white macula appearance.Medically usually this pathological changes depigmentation.The traditional Chinese medical science claims that vitiligo is " leucoderma ", " vitiligo " etc.The traditional Chinese medical science thinks that leukodermic pathogeny is that ailment said due to cold or exposure is flourishing in the body, and that sends out gives birth in table.Its cause of disease many with chemical contamination, interior wound, psychic trauma, pernicious anemia, hyperthyroidism, diabetes, too much take tranquilizer and the endocrine disturbance that causes, immunologic hypofunction, qi depression to blood stasis etc. are relevant.
The therapy for vitiligo means have hormonal medicaments treatment, ultraviolet irradiation treatment, skin grafting treatment and immunization therapy etc. at present.But above therapeutic scheme can only be treated to surperficial disease, can not thoroughly effect a radical cure to be prone to recurrence, brings great pressure and misery to the patient.
Summary of the invention
The purpose of this invention is to provide the leukodermic Chinese medicine of a kind of treatment, it is to the inherent pathogenic factor of vitiligo, distinguishes that disease executing control, and curative effect is fast, and cost is low, and has no side effect, and can reach the effect of treating both the principal and secondary aspects of a disease.
The present invention adopts following technical scheme: the leukodermic medicine of a kind of treatment; In weight portion; Comprise following component: Radix Rehmanniae 25-35; Radix Paeoniae Rubra 12-18, Radix Salviae Miltiorrhizae 12-18, Radix Angelicae Sinensis 9-15, Rhizoma Chuanxiong 9-15, Semen Persicae 8-12, Radix Scutellariae 8-12, Radix Sanguisorbae 7-11, Herba Schizonepetae 7-11, windproof 7-11 、 Herba Siegesbeckiae 7-11, Cortex Dictamni 9-15, Fructus Kochiae 9-15, Zaocys 7-11, Radix Glycyrrhizae 2-4.
The Analysis on Mechanism of Chinese medicine of the present invention:
The Radix Rehmanniae: sweetness and bitterness, cold.Go into the heart, liver, kidney channel.Clearing away heat and cooling blood, yin nourishing is promoted the production of body fluid.Control fever due to yin deficiency, quench one's thirst, spit blood, epistaxis, metrorrhagia, menoxenia, frequent fetal movement, the moon is hindered constipation.
Radix Paeoniae Rubra: bitter in the mouth, cold nature.Return Liver Channel.Function with clearing away heat and cooling blood, eliminating stasis to stop pain.Giving birth to Radix Paeoniae Rubra wins with clearing away heat and cooling blood power.The fever of the body that is used for the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases hemorrhage more, conjunctival congestion and swelling pain, carbuncle sore tumefacting virus.The purgation of spleen excess fire, sending down the abnormal ascending QI, promoting the circulation of blood, removing blood stasis with potent drugs, the clot that looses ends stomachache, moves back heat in blood, attacks the carbuncle skin ulcer, controls mange (" the southern regions of the Yunnan Province book on Chinese herbal medicine ").
Radix Salviae Miltiorrhizae: bitter in the mouth; Cold nature.GUIXIN; Pericardium; Liver Channel.Blood circulation promoting and blood stasis dispelling; Menstruction regulating and pain relieving; Nourishing blood to tranquillize the mind; The removing heat from blood eliminating carbuncle.Can be used for heat and go into nutrient blood, dysphoria, vexed insomnia, carbuncle pyogenic infections from tumour or sore." herbal classic ": main trusted subordinate's pathogen, borborygmus are faint as leaking water, and cold and heat gather; Broken disease is removed abdominal mass, ends stuffy sensation with restlessness, QI invigorating.
Radix Angelicae Sinensis: warm in nature, hide sweet, hot.Return liver, the heart, spleen channel.Enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Materia Medica of Decoction: " Radix Angelicae Sinensis, few the moon of starting with, with its heart master blood also; It is lunar to go into foot, wraps up in blood also with its spleen; Go into the sufficient the moon of fainting, also with its blood stored in the liver.”
Rhizoma Chuanxiong: acrid in the mouth, warm in nature.Return liver, gallbladder, pericardium channel.Blood circulation promoting and blood stasis dispelling; Activating QI to alleviate the depression; Wind-expelling pain-stopping." herbal classic ": main apoplexy is gone into the brain headache, arthralgia due to cold, and the clonic spasm of the muscle emergency, the gold wound, married woman's blood closes loss of fecundity.
Semen Persicae: bitter, sweet, flat.GUIXIN, liver, large intestine channel.Blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, relieving cough and asthma.Be used for amenorrhea, dysmenorrhea , WEIJIA mass in the abdomen, injury from falling down, dryness of the intestine constipation." medication heart method ": Semen Persicae, bitter to let out stagnant blood, sweet with tissue regeneration promoting blood, so blood coagulation must be used.Heat in dehematizing again.
Radix Scutellariae: hardship, cold.Return lung, gallbladder, spleen, large intestine, small intestine meridian.Heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive, blood pressure lowering." detailed outline ": control the damp and hot headache of wind heat, renal mass burning pain, cough caused by pathogenic fire, consumptive lung disease larynx, all losing blood.
Radix Sanguisorbae: picric acid; Cold; Nontoxic.Return liver; Lung; Kidney; Large intestine channel.Cooling blood for hemostasis, heat-clearing and toxic substances removing, skin ulcer is held back in detumescence." not Lu ": end pus and blood, all flaccidity, malignant boil, the wine that disappears removes and quenches one's thirst, and mends exhausted the wound, and plug can be made incised wound cream in puerperal.Main internal hemorrhage due to trauma is more than, insufficiency of blood.
Herba Schizonepetae: suffering, tepor.Return lung, Liver Channel.The diffusing wind that induces sweat, rash, the skin ulcer that disappears, hemostasis.Be used for flu, it is not smooth that measles pass through to be sent out, and has blood in stool, metrorrhagia, epistaxis." the southern regions of the Yunnan Province book on Chinese herbal medicine ": control traumatic injury, and deposited skin infection.Control haematemesis.Herba Schizonepetae, all wind of last refresh oneself ends headache, makes eye bright, and separates lung, liver, throat burning pain, and detumescence removes all poison, disperses carbuncle sore.Treating hematochezia ends woman's sudden onset of metrorrhagia, pathogenic wind expelling heat, and logical lung qi nose key plug closes.
Windproof: acrid in the mouth, sweet, slightly warm in nature.Return bladder, liver, spleen channel.Expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion is jerked surely." herbal classic ": main big dizziness due to wind pain, aversion to wind, ailment said due to cold or exposure, blindness does not have finding, is in fashion the whole body, arthralgia numbness, stuffy sensation with restlessness.
Herba Siegesbeckiae: bitter in the mouth, cool in nature.Wind-damp dispelling, sharp joint, detoxifcation.Be used for that rheumatic arthralgia, muscles and bones are unable, soreness of the waist and knees, quadriplegia, hemiplegia, rubella eczema." detailed outline ": " treating the liver the kidney-wind syndrome gas, quadriplegia, a little less than the osteodynia knee joint, all skin ulcers of rheumatism.”
Cortex Dictamni: bitter in the mouth, cold.Go into lunar, the Yangming Channel of foot, double staff too yin, yang is bright.Dispel the wind dampness, heat clearing away, detoxifcation.Control the wind heat sore, scabies, itchy skin eruption, rheumatic arthralgia, jaundice.Control all pyretic toxicity wind, aversion to wind, wind skin ulcer, scabies are red mashed, and the eyebrow loss of hairs is crisp, and musculus cutaneus is anxious, the high fever aversion to cold; Principal solution heat is yellow, wine is yellow, (" property of medicine opinions ") such as acute jaundices, paddy Huang, labor Huang.
The Fructus Kochiae: cold in nature, acrid in the mouth, hardship.Go into kidney, urinary bladder channel.Long-pending heat in the peeling skin is removed skin exogenous damp itch (" book on Chinese herbal medicine is original ").Other has the anti-dermatophyte effect, and its water logging agent is all had inhibitory action in various degree to permitting dermatophytess such as blue achorion, Du's big belly microspore tinea bacterium difficult to understand, rust microspore's tinea bacterium, ulotrichy microspore's tinea bacterium, star-shaped nocardia.
Zaocys: sweet, flat.Return Liver Channel.Dispel the wind collateral dredging, relieving convulsion.Be used for rheumatoid arthritis stubborn, numbness contracture, apoplexy facial hemiparalysis, hemiplegia, tic spasm, tetanus, leprosy scabies, scrofula malignant boil.
Radix Glycyrrhizae: property is flat, and sweet in the mouth is returned 12 warps.Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.
The person of choosing in the side, heat clearing and blood cooling, expelling pathogenic wind from the body surface, with the Radix Rehmanniae, Radix Paeoniae Rubra, Radix Scutellariae, Radix Sanguisorbae clearing away heat and cooling blood, eliminating fire and detoxication is to be principal agent; Enrich blood with Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, Rhizoma Chuanxiong and to invigorate blood circulation, the blood stasis dispelling dissipating depression of QI, mutual reinforcement between is a usefulness, is be ministerial drug; Assistant is loose with Herba Schizonepetae, Fang Feng 、 Herba Siegesbeckiae, the Fructus Kochiae, Zaocys and is shown to dispel the wind, detoxify, Radix Glycyrrhizae and middle emergency coordinating the actions of various ingredients in a prescription, and with all medicine compatibilities, dispelling wind and removing obstruction in the collateral, inducting the medicines into affected channel is with the persistent ailment of dispelling.Full side plays heat clearing and blood cooling altogether, the merit of expelling pathogenic wind from the body surface, and to the vitiligo determined curative effect, effect is remarkable, double taking stopgap measures originally.
Form of Chinese drug of the present invention can adopt tablet, granule, pill, capsule, solution, oral liquid, buccal tablet, granule, electuary, powder, suspensoid, powder.Preferably, can adopt solution, granule, pill and capsule.
Result of use
The curative effect judgment criteria:
1. cure: white macula disappears fully, and it is normal that pigment recovers, upward nothing recurrence in 1 month.
2. produce effects: white macula disappears basically, and pigment recovers normally to still have the white macula scabies of very small amount basically.
3. effective: white macula begins to disappear, and it is normal that pigment begins to recover, and the 20%-50% white macula disappears.
4. invalid: white macula is not seen and is disappeared.
50 patients with vitiligo (age 27-47) are used the leukodermic Chinese medicine of treatment of the present invention, and 1 course of treatment of continued treatment (2 months), wherein 14 examples are cured fully, transference cure; 12 routine symptoms are obviously alleviated, and white macula disappears, and pigment recovers normally to be produce effects basically; 20 routine symptoms are alleviated to some extent, and the rash piece reduces; Invalid 4 examples, overall effective percentage reaches 92%.Treatment has no side effect, routine test, hepatic and renal function inspection no abnormality seen.
Instance:
The patient 1: appoint certain, and the women, 27 years old, the existing button size of back cervical region white macula, the treatment of applying ointment is not felt any better, and the expansion trend of stretching is arranged, and after 1 month, white macula also appears in lower jaw portion, and hospital is diagnosed as vitiligo.The western medicine effect is not good enough, after bring into use Chinese medicine of the present invention upon somebody's introduction, after 1 course of treatment; The trend of white macula diffusion has been brought under control, and continues to use 1 course of treatment, and back cervical region white macula begins to disappear; Melanin increases, and the white macula on lower jaw the back of the hand reduces, after the 3rd course of treatment; Pigment recovers normal level, and white macula disappears, and does not have recurrence so far.
The patient 2: the Wang, and the male, 26 years old, the existing large stretch of white macula in shirtfront had diffusion tendency, and it is early stage that hospital confirms as vitiligo.Take Chinese medicine of the present invention, after 1 course of treatment, white macula begins to disappear, and pigment progressively recovers.Continue to take medicine 1 course of treatment, symptom disappears basically, and the colour of skin is normal, does not have recurrence.
The patient 3: do certain, and the male, 33 years old, white point all appearred in both hands the back of the hand portion, and white point begins to enlarge after 1 month, and it is whiter to become simultaneously, removes examination in hospital, is diagnosed as general property vitiligo.Western medicine, effect is not good enough.Use 1 course of treatment of Chinese medicine of the present invention, white macula stretch and diffusion is able to control, continue to take 1 course of treatment, pigment generates, white macula begins to disappear, white macula diminishes.After 3 courses of treatment, the pigment at white macula place has recovered normal level, and white macula disappears, and does not have recurrence so far.
The patient 4: Huang, and the male, 41 years old, 3 white maculas of forehead grain of rice shape, beginning is not treated, and white macula enlarges, merges the white macula that forms a button size after 1 month, is diagnosed as vitiligo through hospital.The patient seeks medical advice everywhere, and is very worried, but effect is bad, the state of an illness commentaries on classics of not getting better.Used Chinese medicine of the present invention afterwards, after 1 course of treatment, the diffusion of white macula is controlled, and the white macula color deepens gradually, and pigment begins to recover.Continue to take medicine 1 course of treatment, white macula obviously dwindles, and pigment also becomes and come almost consistently with on every side, continues to take medicine half the course of treatment, and pigment recovers normally basically, and the white macula naked eyes are respectively difficult, is almost recovered, and 2 fully recover after all, do not see recurrence so far half a year.
The specific embodiment
In order to understand the present invention better, through embodiment the present invention is described below.
Embodiment 1
The leukodermic medicine of a kind of treatment; In weight portion; Comprise following component: the Radix Rehmanniae 25, Radix Paeoniae Rubra 12, Radix Salviae Miltiorrhizae 12, Radix Angelicae Sinensis 9, Rhizoma Chuanxiong 9, Semen Persicae 8, Radix Scutellariae 8, Radix Sanguisorbae 7, Herba Schizonepetae 7, windproof 7 、 Herba Siegesbeckiaes 7, Cortex Dictamni 9, the Fructus Kochiae 9, Zaocys 7, Radix Glycyrrhizae 2.
Its preparation method is:
In weight portion, get the Radix Rehmanniae 25, Radix Paeoniae Rubra 12, Radix Salviae Miltiorrhizae 12, Radix Angelicae Sinensis 9, Rhizoma Chuanxiong 9, Semen Persicae 8, Radix Scutellariae 8, Radix Sanguisorbae 7, Herba Schizonepetae 7, windproof 7 、 Herba Siegesbeckiaes 7, Cortex Dictamni 9, the Fructus Kochiae 9, Zaocys 7, Radix Glycyrrhizae 2; Above-mentioned Chinese medicine is cleaned, and decontamination is put into container and is added water and do not have medical material to soak, and after 30 minutes, big fire decocts to boiling, and slow fire was endured 1 hour slowly then; Medicine juice is leached, bag distribution packaging, one bag of 200ml sooner or later respectively obey one bag, but the dual-purpose medicinal liquid is smeared affected part.
Embodiment 2
The leukodermic medicine of a kind of treatment; In weight portion; Comprise following component: the Radix Rehmanniae 35, Radix Paeoniae Rubra 18, Radix Salviae Miltiorrhizae 18, Radix Angelicae Sinensis 15, Rhizoma Chuanxiong 15, Semen Persicae 12, Radix Scutellariae 12, Radix Sanguisorbae 11, Herba Schizonepetae 11, windproof 11 、 Herba Siegesbeckiaes 11, Cortex Dictamni 15, the Fructus Kochiae 15, Zaocys 11, Radix Glycyrrhizae 4.
Its preparation method is:
In weight portion, get the Radix Rehmanniae 35, Radix Paeoniae Rubra 18, Radix Salviae Miltiorrhizae 18, Radix Angelicae Sinensis 15, Rhizoma Chuanxiong 15, Semen Persicae 12, Radix Scutellariae 12, Radix Sanguisorbae 11, Herba Schizonepetae 11, windproof 11 、 Herba Siegesbeckiaes 11, Cortex Dictamni 15, the Fructus Kochiae 15, Zaocys 11, Radix Glycyrrhizae 4; Cleaning, drying mix above-mentioned medical material, and per kilogram adds about 10L water, and 0.5-1 at a simmer hour, big fire was fried in shallow oil 1-2 hour; Get decocting liquid and cross 150 mesh sieves, the back is concentrated into the clear paste of relative density 1.10-1.20 with concentrator, gets 2/3 clear paste 120 ℃ of following spray dryinges, the clear paste powder, powder is mixed granulation with residue 1/3 clear paste; The packing of granule racking machine promptly gets granule.
Embodiment 3
The leukodermic medicine of a kind of treatment; In weight portion; Comprise following component: the Radix Rehmanniae 30, Radix Paeoniae Rubra 15, Radix Salviae Miltiorrhizae 15, Radix Angelicae Sinensis 12, Rhizoma Chuanxiong 12, Semen Persicae 10, Radix Scutellariae 10, Radix Sanguisorbae 9, Herba Schizonepetae 9, windproof 9 、 Herba Siegesbeckiaes 9, Cortex Dictamni 12, the Fructus Kochiae 12, Zaocys 9, Radix Glycyrrhizae 3.
Its preparation method is:
In weight portion, get the Radix Rehmanniae 30, Radix Paeoniae Rubra 15, Radix Salviae Miltiorrhizae 15, Radix Angelicae Sinensis 12, Rhizoma Chuanxiong 12, Semen Persicae 10, Radix Scutellariae 10, Radix Sanguisorbae 9, Herba Schizonepetae 9, windproof 9 、 Herba Siegesbeckiaes 9, Cortex Dictamni 12, the Fructus Kochiae 12, Zaocys 9, Radix Glycyrrhizae 3; Cleaning, drying mix above-mentioned medical material, use pulverizer to pulverize and are 150-180 order fine powder, and add suitable Mel and mix, the pellet processing machine pill, cold drying, packing promptly gets pill.
Embodiment 4
The leukodermic medicine of a kind of treatment; In weight portion; Comprise following component: the Radix Rehmanniae 30, Radix Paeoniae Rubra 15, Radix Salviae Miltiorrhizae 15, Radix Angelicae Sinensis 12, Rhizoma Chuanxiong 12, Semen Persicae 10, Radix Scutellariae 10, Radix Sanguisorbae 9, Herba Schizonepetae 9, windproof 9 、 Herba Siegesbeckiaes 9, Cortex Dictamni 12, the Fructus Kochiae 12, Zaocys 9, Radix Glycyrrhizae 3.
Its preparation method is:
In weight portion, get the Radix Rehmanniae 30, Radix Paeoniae Rubra 15, Radix Salviae Miltiorrhizae 15, Radix Angelicae Sinensis 12, Rhizoma Chuanxiong 12, Semen Persicae 10, Radix Scutellariae 10, Radix Sanguisorbae 9, Herba Schizonepetae 9, windproof 9 、 Herba Siegesbeckiaes 9, Cortex Dictamni 12, the Fructus Kochiae 12, Zaocys 9, Radix Glycyrrhizae 3; Cleaning, drying mix above-mentioned medical material, and per kilogram adds about 10L water, and 0.5-1 at a simmer hour, big fire was fried in shallow oil 1-2 hour; Get decocting liquid and cross 150 mesh sieves, the back is concentrated into the clear paste of relative density 1.10-1.20 with concentrator, gets 2/3 clear paste 120 ℃ of following spray dryinges, the clear paste powder, powder is mixed granulation with residue 1/3 clear paste; Granule is processed the 0.4g/ capsules with the capsule filler.

Claims (4)

1. treat leukodermic medicine for one kind; It is characterized in that; In weight portion; Comprise following component: Radix Rehmanniae 25-35, Radix Paeoniae Rubra 12-18, Radix Salviae Miltiorrhizae 12-18, Radix Angelicae Sinensis 9-15, Rhizoma Chuanxiong 9-15, Semen Persicae 8-12, Radix Scutellariae 8-12, Radix Sanguisorbae 7-11, Herba Schizonepetae 7-11, windproof 7-11 、 Herba Siegesbeckiae 7-11, Cortex Dictamni 9-15, Fructus Kochiae 9-15, Zaocys 7-11, Radix Glycyrrhizae 2-4.
2. medicine according to claim 1; It is characterized in that; In weight portion; Preferably comprise following component: the Radix Rehmanniae 30, Radix Paeoniae Rubra 15, Radix Salviae Miltiorrhizae 15, Radix Angelicae Sinensis 12, Rhizoma Chuanxiong 12, Semen Persicae 10, Radix Scutellariae 10, Radix Sanguisorbae 9, Herba Schizonepetae 9, windproof 9 、 Herba Siegesbeckiaes 9, Cortex Dictamni 12, the Fructus Kochiae 12, Zaocys 9, Radix Glycyrrhizae 3.
3. medicine according to claim 1 is characterized in that, said medicine adopts tablet, granule, pill, capsule, solution, oral liquid, buccal tablet, granule, electuary, powder, suspensoid, powder.
4. medicine according to claim 1 is characterized in that said medicine preferably adopts solution, granule, pill and capsule.
CN2011102586625A 2011-09-04 2011-09-04 Drug for treating leucoderma Pending CN102366469A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106822653A (en) * 2017-03-28 2017-06-13 黄清新 A kind of Chinese medicine composition for treating leucoderma
CN108079240A (en) * 2017-12-25 2018-05-29 广西壮要方医院有限公司 A drug for treating vitiligo
CN111419922A (en) * 2020-05-21 2020-07-17 杨得贵 A Chinese medicinal composition for treating vitiligo, and its preparation method

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106822653A (en) * 2017-03-28 2017-06-13 黄清新 A kind of Chinese medicine composition for treating leucoderma
CN108079240A (en) * 2017-12-25 2018-05-29 广西壮要方医院有限公司 A drug for treating vitiligo
CN111419922A (en) * 2020-05-21 2020-07-17 杨得贵 A Chinese medicinal composition for treating vitiligo, and its preparation method

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Application publication date: 20120307