CN101579509B - Traditional Chinese medicine preparation for treating premature beat of cardiac rhythm - Google Patents
Traditional Chinese medicine preparation for treating premature beat of cardiac rhythm Download PDFInfo
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- CN101579509B CN101579509B CN2009100745475A CN200910074547A CN101579509B CN 101579509 B CN101579509 B CN 101579509B CN 2009100745475 A CN2009100745475 A CN 2009100745475A CN 200910074547 A CN200910074547 A CN 200910074547A CN 101579509 B CN101579509 B CN 101579509B
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating premature beat of cardiac rhythm. For the preparation, the proportioning by weight of the effective components thereof is as follows: 30 to 60 portions of ostericum citriodorum, 20 to 40 portions of radix codonopsitis, 15 to 30 portions of old arable soil, 10 to 30 portions of salvia miltiorrhiza, 10 to 30 portions of fructus trichosanthis, 15 to 30 portions of radix puerariae, 15 to 30 portions of hiraute shiny bugleweek herb, 10 to 20 portions of radix curcumae, 10 to 20 portions of kuh-seng, 10 to 30 portions of herba artemisiae, 5 to 10 portions of peach kernel and 10 to 20 portions of safflower. Compatibility and progression of medicines are reasonable, and all medicines jointly perform favorable efficacies. After the traditional Chinese medicine preparation of the invention is taken, the effective rate of preventing and treating premature beat of cardiac rhythm in 30 days is 100%, and the effective rate for treating sudden occurring disease is 97%; effective rate in 60 days is 100%, and cure rate is 95%.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, especially a kind of Chinese medicine preparation for the treatment of premature beat of cardiac rhythm.
Background technology
Premature beat of cardiac rhythm claims premature beat again, abbreviates " premature beat " as, is meant that ectopic pacemaker sends out the caused heartbeat of too early impulsion that hits.Premature beat is general and the most common ectopic cardiac rhythm.According to the dystopy starting point position difference of fighting, premature beat can be divided into three kinds of room, atrioventricular junction and chamber property.
Wherein common with chamber property, premature beat can be accidental or distribute, and also can be frequent appearance.
The reason of premature beat is numerous, is difficult for sometimes clinically deciding, and at first some healthy images can take place, and excessive consumption of alcohol, smoking, drinks strong tea, fatigue, anxious state of mind etc. and often can bring out premature beat.Organic heart disease is more common in premature beat, as coronary heart disease, myocarditis, cardiomyopathy, valvulopathy etc.Secondly premature beat sees the toxic and side effects of some drugs, as epinephrine, and Buddhist nun's fourth, Folium Digitalis Purpureae etc., electrolyte disturbance in addition, open chest surgery and cardiac catheterization also can cause premature beat.
Summary of the invention
The technical problem to be solved in the present invention provides the Chinese medicine preparation of a kind of effective prevention and treatment premature beat of cardiac rhythm and high effect nontoxic side effect.
For solving the problems of the technologies described above, the Chinese medicine preparation of treatment premature beat of cardiac rhythm, the weight proportion for preparing its raw materials of effective components is: Radix osterici citriodori (Radix Angelicae Citriodorae) 30-60 part, Radix Codonopsis 20-40 part, Radix Rehmanniae Preparata 15-30 part, Radix Salviae Miltiorrhizae 10-30 part, Fructus Trichosanthis 10-30 part, Radix Puerariae 15-30 part, Herba Lycopi 15-30 part, Radix Curcumae 10-20 part, Radix Sophorae Flavescentis 10-20 part, Herba Artemisiae Anomalae 10-30 part, Semen Persicae 5-10 part, Flos Carthami 10-20 part.
The technical scheme of the further technical solution of the present invention is: the weight proportion for preparing its raw materials of effective components is: 30 parts of Radix osterici citriodori (Radix Angelicae Citriodorae)s, 20 parts of Radix Codonopsis, 20 parts in Radix Rehmanniae Preparata, 25 parts of Radix Salviae Miltiorrhizaes, 25 parts of Fructus Trichosanthis, 20 parts of Radix Puerariaes, 15 parts of Herba Lycopi, 15 parts of Radix Curcumaes, 20 parts of Radix Sophorae Flavescentiss, 10 parts of Herba Artemisiae Anomalaes, 6 parts in Semen Persicae, 10 parts on Flos Carthami.
The side of the Chinese medicine preparation of the present invention's treatment " premature beat of cardiac rhythm " separates as follows:
Radix osterici citriodori (Radix Angelicae Citriodorae): nature and flavor, pains are flat, and function cures mainly: the heat clearing away of stream wind, promoting the circulation of QI to relieve pain, promoting blood circulation to remove blood stasis, motive pain, activating QI pain relieving.
Radix Codonopsis: nature and flavor, sweet flat, function cures mainly: invigorating the spleen and replenishing QI, the qi of chong channel ascending adversely weakness, food back distending pain, blood deficiency and yellow complexion, dizziness, lassitude of the limbs and weakness, QI invigorating is enriched blood.
Radix Rehmanniae Preparata: nature and flavor, sweet tepor, function cures mainly: the hepatic and renal YIN deficiency, the blood deficiency deficiency, order is secretly dizzy, cardiopalmus, kidney tonifying promotes the production of body fluid.
Radix Salviae Miltiorrhizae: nature and flavor, hardship is slightly cold, and function cures mainly: blood circulation promoting and blood stasis dispelling, the removing heat from blood relieving restlessness, the heat in blood stasis of blood stagnates, tranquilizing the mind, abdominal mass.
Fructus Trichosanthis: nature and flavor, sweet cold, function cures mainly: removing heat-phlegm, the septum pectorale unhappiness, the thoracic obstruction, pained, scorchingly hot pent-up.
Radix Puerariae: nature and flavor, do willingly flat, function cures mainly: expelling pathogenic factors from muscles for reducing heat, promoting the production of body fluid to quench thirst, the empty sense in Tianjin wind, fever and headache, the strongly fragrant table of wind heat.
The Herba Lycopi: nature and flavor, the pains tepor, function cures mainly: promoting the circulation of blood blood stasis dispelling, the detumescence of stimulating the menstrual flow, blood stasis water meter, dysmenorrhea, stomachache.
Radix Curcumae: nature and flavor, arduous cold, function cures mainly: cooling blood and removing stasis, promoting QI circulation for relieving depression, qi depression to blood stasis, costalgia uncomfortable in chest.
Radix Sophorae Flavescentis: the nature and flavor bitter cold, function cures mainly: heat clearing and damp drying, the fire of dispelling that detoxifies, retention of damp-heat in the interior, jaundice, infantile malnutrition, edema, dysuria.
Herba Artemisiae Anomalae: nature and flavor, bitter temperature; Function cures mainly: removing blood stasis stimulates the menstrual flow, softening the hard mass removing food stagnancy, blood stasis amenorrhea, postpartum stagnation, pain due to blood stasis.
Semen Persicae: nature and flavor, bitter sweet flat, function cures mainly: blood stasis removing and clots absorbing, the intestine moistening blood stasis congelation, dysmenorrhea, swelling, stomachache, costalgia, enterodynia, blood is dry not to be moistened.
Flos Carthami: nature and flavor, Xin Wen, function cures mainly: promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing, blood stasis congelation, stomachache, bruise, Guan Jie Paralysis pain.
The present invention is with pure Chinese medicine system side, premature beat of cardiac rhythm, and deepened the negative and positive of human body are regulated the enhance immunity ability, adjust the rhythm of the heart, qi and blood tonifying, benefiting QI and nourishing blood, unimpeded stasis of blood resistance, promoting blood circulation to remove obstruction in the collateral is a monarch drug with the Radix osterici citriodori (Radix Angelicae Citriodorae), wind and heat dispersing, blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain are joined Radix Codonopsis, reinforcing the heart temperature sun, Radix Rehmanniae Preparata, removing heat from blood relieving restlessness, liver and kidney tonifying, Radix Salviae Miltiorrhizae, blood circulation promoting and blood stasis dispelling stagnates, the expansion peripheral vessels.Fructus Trichosanthis, expelling pathogenic factors from muscles for reducing heat, detoxicating and resolving stagnation of pathogens, Radix Puerariae, promoting the production of body fluid to quench thirst, Herba Lycopi, promoting the circulation of blood blood stasis dispelling, the water that disappears of ventilating, the stagnation of the blood, cooling blood and removing stasis, promoting QI circulation for relieving depression, Radix Sophorae Flavescentis, heat clearing and damp drying, detoxifcation removing food stagnancy.Herba Artemisiae Anomalae, removing blood stasis stimulates the menstrual flow, reducing swelling and alleviating pain, Semen Persicae, the clots absorbing eliminating stagnation is eliminated lump, pain relieving, Flos Carthami, promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing.
All medicine compatibilities are reasonable, gather good effect altogether, in prevention and treatment premature beat of cardiac rhythm disease, take this invention medicine after, effective percentage 100% on 30th, the disease that breaks out effective percentage is that effective percentage on the 97%, 60 is 100%, cure rate 95%.
Chinese medicine preparation of the present invention is the prevention ventricular tachycardia to the main purpose of Treatment of Ventricular Extrasystole, ventricular fibrillation and sudden death as ventricular premature contraction during without organic heart disease, and non-ly occur in pairs or continuously, after the premature beat, compensatory pause is completely often arranged, the most non-evident sympton of occasional premature beat, but also had palpitation, or feel to have certain heart beating, suddenly increase the weight of or have heart beating to suspend to feel, frequent premature beat causes weak dizziness when cardiac output is reduced, and is uncomfortable in chest etc.
Toxicity test: the medicine of the present invention being treated premature beat of cardiac rhythm is given 150 mice lavage administration 20g medicinal liquid/kg, 40 times of quite clinical human body consumption, the viewing duration animal diet followed is normal, do not see that the animal generation is dead, animal activity reduces to some extent after irritating stomach, but animal survival is in good condition, recovers normal behind the 8h, illustrates that it is safe that said preparation is taken.
Preparation method: each raw material is carried out the strictness screening, purify, oven dry takes by weighing, and the pharmaceutical technology flow process produces all types of pharmaceutical preparatioies routinely then, as makes oral Chinese medicine liquid, concentrated granular electuary, tablet or capsule.
Instructions of taking: make the Chinese medicine preparation for the treatment of premature beat of cardiac rhythm by the Chinese medicine of material combination of the present invention, divided in one day and take for two to three times, 30 is a course of treatment, takes capsule of the present invention one to three time, and each two, 30 days is a course of treatment.
The inventor is to 200 routine case clinical observations, male 120 people wherein, and women 80 people, 35 years old-75 years old age, by taking medicine of the present invention, general medication 30 days, effective percentage is 100%, cure rate reaches 94%.
Model case 1: Lu, the woman, 38 years old, QI and blood deficiency, cardiopalmus, dizziness and blurred vision is suffered from the ventricular premature contraction tachycardia, and the electrocardiogram demonstration occurs ahead of time, the QRS-T wave group of roomy deformity, and do not have P ripple in advance, through taking 4 all disease eliminations course of treatment of capsule of the present invention.
Model case 2: Zhang, the man, 65 years old, the cadre suffered from coronary heart disease, the frequent sensation of oppression over the chest with shortness of breath of ventricular premature contraction, chest pain, palpitation and insomnia, body of the tongue is livid purple, recovers normal 3 courses of treatment through taking capsule of the present invention.
Model case 3: gold certain, the woman, 56 years old, the workman suffered from the ventricular premature contraction tachycardia, ventricular fibrillation, stagnation of heart-blood is felt oppressed and is not relaxed, insomnia forgetfulness is through taking 3 recoveries from illness courses of treatment of capsule of the present invention.
Model case 4: Yao, the man, 55 years old, suffer from the ventricular premature contraction 2 years of taking place frequently, nervous breathing hard, dizziness and blurred vision, insomnia forgetfulness, stagnation of heart-blood, thready pulse knot generation, medicament 15 pairs in taking the present invention, symptom reduces by half, and obeys 3 courses of treatment of capsule of the present invention again, recovers.
Model case 5: the Wang, the man 60 years old, suffered from rheumatic heart disease, ventricular premature contraction 3 years, the QRS-T wave group of roomy deformity appears in electrocardiogram, and does not have P ripple in advance, and individual ripple direction is opposite with QRS group's main ripple direction, often suppresses awake midnight, lip and nail are purple dark, through taking 4 courses of treatment of capsule of the present invention, transference cure.
Model case 6: poplar, the man 58 years old, suffers from a heart complaint, angina pectoris, ventricular premature contraction, qi depression to blood stasis, cardiopalmus disease is swollen, insomnia forgetfulness, and lusterless complexion, in thready pulse, puckery, knot generation, body of the tongue, are livid purple, medicament 10 pairs in taking the present invention, sx is obeyed 3.5 courses of treatment of capsule of the present invention again, recovery from illness.
The specific embodiment
Embodiment 1: the Chinese medicine preparation of this treatment premature beat of cardiac rhythm, adopt following components by weight percent preparation, Radix osterici citriodori (Radix Angelicae Citriodorae) 30g, Radix Codonopsis 20g, Radix Rehmanniae Preparata 20g, Radix Salviae Miltiorrhizae 25g, Fructus Trichosanthis 25g, Radix Puerariae 20g, Herba Lycopi 15g, Radix Curcumae 15g, Radix Sophorae Flavescentis 20g, Herba Artemisiae Anomalae 10g, Semen Persicae 6g, Flos Carthami 10g.
Preparation method: each raw material is carried out the strictness screening, purify, oven dry takes by weighing, and the pharmaceutical technology flow process produces all types of pharmaceutical preparatioies routinely then, as makes oral Chinese medicine liquid, concentrated granular electuary, tablet or capsule.
Embodiment 2-5: adopt the feedstock production of following weight, preparation method and taking with embodiment 1.
| Embodiment 2 | Embodiment 3 | Embodiment 4 | Embodiment 5 | |
| Radix osterici citriodori (Radix Angelicae Citriodorae) (g) | 30 | 60 | 40 | 50 |
| Radix Codonopsis (g) | 40 | 20 | 35 | 28 |
| Radix Rehmanniae Preparata (g) | 15 | 30 | 20 | 25 |
| Radix Salviae Miltiorrhizae (g) | 30 | 10 | 15 | 20 |
| Fructus Trichosanthis (g) | 10 | 30 | 20 | 12 |
| Radix Puerariae (g) | 30 | 15 | 20 | 24 |
| Herba Lycopi (g) | 15 | 30 | 25 | 12 |
| Radix Curcumae (g) | 20 | 10 | 12 | 18 |
| Radix Sophorae Flavescentis (g) | 10 | 20 | 15 | 12 |
| Herba Artemisiae Anomalae (g) | 30 | 10 | 25 | 15 |
| Semen Persicae (g) | 5 | 10 | 7 | 6 |
| Flos Carthami (g) | 20 | 10 | 18 | 13 |
Claims (4)
1. treat the Chinese medicine preparation of premature beat of cardiac rhythm, it is characterized in that the weight proportion for preparing its raw materials of effective components is:
Radix osterici citriodori (Radix Angelicae Citriodorae) 30-60 part, Radix Codonopsis 20-40 part, Radix Rehmanniae Preparata 15-30 part, Radix Salviae Miltiorrhizae 10-30 part, Fructus Trichosanthis 10-30 part, Radix Puerariae 15-30 part, Herba Lycopi 15-30 part, Radix Curcumae 10-20 part, Radix Sophorae Flavescentis 10-20 part, Herba Artemisiae Anomalae 10-30 part, Semen Persicae 5-10 part, Flos Carthami 10-20 part.
2. the Chinese medicine preparation of treatment premature beat of cardiac rhythm according to claim 1 is characterized in that the weight proportion for preparing its raw materials of effective components is:
30 parts of Radix osterici citriodori (Radix Angelicae Citriodorae)s, 20 parts of Radix Codonopsis, 20 parts in Radix Rehmanniae Preparata, 25 parts of Radix Salviae Miltiorrhizaes, 25 parts of Fructus Trichosanthis, 20 parts of Radix Puerariaes, 15 parts of Herba Lycopi, 15 parts of Radix Curcumaes, 20 parts of Radix Sophorae Flavescentiss, 10 parts of Herba Artemisiae Anomalaes, 6 parts in Semen Persicae, 10 parts on Flos Carthami.
3. according to the Chinese medicine preparation of any one described treatment premature beat of cardiac rhythm among the claim 1-2, it is characterized in that described Chinese medicine preparation is the oral formulations form.
4. the Chinese medicine preparation of treatment premature beat of cardiac rhythm according to claim 3 is characterized in that described Chinese medicine preparation is capsule, tablet, electuary, powder, oral liquid formulations form.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009100745475A CN101579509B (en) | 2009-06-29 | 2009-06-29 | Traditional Chinese medicine preparation for treating premature beat of cardiac rhythm |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009100745475A CN101579509B (en) | 2009-06-29 | 2009-06-29 | Traditional Chinese medicine preparation for treating premature beat of cardiac rhythm |
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| Publication Number | Publication Date |
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| CN101579509A CN101579509A (en) | 2009-11-18 |
| CN101579509B true CN101579509B (en) | 2011-09-21 |
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| CN2009100745475A Expired - Fee Related CN101579509B (en) | 2009-06-29 | 2009-06-29 | Traditional Chinese medicine preparation for treating premature beat of cardiac rhythm |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102526220A (en) * | 2012-01-10 | 2012-07-04 | 上海市中医医院 | Chinese medicinal patch for treating premature systole and preparation method and application of Chinese medicinal patch |
| CN105250517A (en) * | 2015-10-07 | 2016-01-20 | 郑文忠 | Traditional Chinese medicine used for treating premature beat |
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Granted publication date: 20110921 Termination date: 20130629 |