CN102178870B - Chinese medicinal preparation for promoting qi circulation, promoting blood circulation, softening hard mass and eliminating stagnation for people with qi-depression and phlegm-damp physique, preparation method thereof and application thereof - Google Patents
Chinese medicinal preparation for promoting qi circulation, promoting blood circulation, softening hard mass and eliminating stagnation for people with qi-depression and phlegm-damp physique, preparation method thereof and application thereof Download PDFInfo
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Abstract
The invention discloses a Chinese medicinal preparation for promoting qi circulation, promoting blood circulation, softening hard mass and eliminating stagnation for people who have qi-depression and blood-stagnation physique, a preparation method thereof and application thereof. The Chinese medicinal preparation comprises the following raw material medicaments in part by mass: 20 to 60 parts of peach seed, 30 to 50 parts of semen sinapis albae, 40 to 70 parts of kelp, 20 to 70 parts of oyster shell, 30 to 80 parts of mongolian dandelion herb, 40 to 60 parts of malt, 30 to 70 parts of liquoric root, 30 to 70 parts of chicken's gizzard-membrane, 10 to 40 parts of seville orange flower, 10 to 40 parts of reddish orange, 20 to 60 parts of tangerine pith, 30 to 80 parts of tangerine seed, 40 to 80 parts of folium citri reticulatae, 30 to 70 parts of medlar, 50 to 80 parts of asparagus, 20 to 70 parts of lucid ganoderma, 40 to 70 parts of agkistrodon halys and 50 to 80 parts of citrus chirocarpus. The Chinese medicinal preparation for promoting qi circulation, promoting blood circulation, softening hard mass and eliminating stagnation for the people with the qi-depression and blood-stagnation physique is subjected to compatibility by plants which are homologous in medicines and food, does not have side effect, and can relieve or eliminate bad symptoms such as proliferation of mammary glands, swollen breasts, breast distention before menstruation and the like of the people with the qi-depression and blood-stagnation physique.
Description
Technical field
The present invention relates to the field of Chinese medicines, be specifically related to be used for that stagnation of QI body constitution, phlegm-dampness constitution people circulation of qi promoting are invigorated blood circulation, the Chinese medicine preparation of hard masses softening and resolving.
Background technology
According to " tcm constitution " Epidemiological study that lasts 30 years; People's body constitution can be divided into nine kinds, is respectively: gentle body constitution, deficiency of vital energy body constitution, stagnation of QI body constitution, deficiency of YIN body constitution, damp and hot body constitution, yang deficiency body constitution, phlegm-dampness constitution, blood stasis body constitution, allergic constitution.
The gas of human body is the basic and power of people's life movement.Keeping of vital movement must rely on gas.The gas of human body, except that relevant with natural endowment, acquired environment and dietetic nutrition, and closely related with the physiological function of kidney, spleen, stomach, lung.So the various physiological activities of body in fact all are the imbodies that gas moves in human body.When gas can not outside reach and tie and gather when interior, just form " stagnation of QI ", stagnation of QI body constitution.
Phlegm-dampness constitution is present more common a kind of constitutional type, and when viscera, imbalance of YIN and YANG, the imbalance of qi-blood-body fluid fortuneization when being prone to form phlegm-damp, can think that just this constitution status is a phlegm-dampness constitution, is more common in the obese people, or the people of plain thin modern fertilizer.The normal performance of the people of this body constitution has the bodily form fat, and the abdominal part grossness is soft, and the skin of face oils and fats is more, hyperhidrosis and sticking; Uncomfortable in chest, abundant expectoration, complexion is yellowish and dark, and the eye born of the same parents are little floating; Sleepy easily, corpulent tongue is big usually, white and greasy fur or sweet, and heavy sensation of the body is not well; Preference for fat and sweet food is sweet sticking, and it is normal or unreal to defecate, few or little the mixing of urinating.Personality is gentle, steady partially, is good at restraining oneself more.This kind constitutional type has the trouble of being prone to hypertension, diabetes, obesity, hyperlipemia, asthma, gout, coronary heart disease, metabolism syndrome, the tendency of diseases such as cerebrovascular disease.
The people of stagnation of QI body constitution and phlegm-dampness constitution has following symptom:
Emaciated physique or fat partially, grey dark or sallow, the being irritable and irascible usually of complexion is easy to excitement, or melancholy joyless; Uncomfortable in chestly do not relax, light red tongue, tongue is white, in case stringy pulse, sick then sternal rib pain or scurry bitterly, breast and lower abdominal distention pain sometimes, menoxenia; Block in dysmenorrhea, the pharynx, if any foreign body or neck goiter, gastral cavilty distending pain, general acid regurgitation water; Singultus gas, stomachache borborygmus, stool lets out the QI rising in reverse order row that profit is not well, body is interior, and it is dizzy to have a headache.
Still the people who does not have at present medicine to the ill to be used for stagnation of QI body constitution, phlegm-dampness constitution improves its symptom.
Summary of the invention
Technical problem to be solved by this invention is that the people who solves stagnation of QI body constitution, phlegm-dampness constitution does not have the problem that symptomatic drugs is improved its symptom.
In order to solve the problems of the technologies described above; The technical scheme that the present invention adopted provide a kind ofly be used for that stagnation of QI body constitution, phlegm-dampness constitution people circulation of qi promoting are invigorated blood circulation, the Chinese medicine preparation of hard masses softening and resolving and preparation method thereof, and provide this Chinese medicine preparation to alleviate or eliminated the application on stagnation of QI body constitution, phlegm-dampness constitution crowd's the ill symptoms.
Provided by the inventionly be used for that stagnation of QI body constitution, phlegm-dampness constitution people circulation of qi promoting are invigorated blood circulation, the Chinese medicine preparation of hard masses softening and resolving, its active ingredient is processed by the crude drug of following mass fraction: Semen Persicae 20-60, Semen Sinapis 30-50, Thallus Laminariae (Thallus Eckloniae) 40-70, Concha Ostreae 20-70, Herba Taraxaci 30-80, Fructus Hordei Germinatus 40-60, Radix Glycyrrhizae 30-70, Endothelium Corneum Gigeriae Galli 30-70, CitrusaurantiumL.Var.amara Engl. 10-40, tangerine 10-40, Vascular aurantii 20-60, Semen Citri Reticulatae 30-80, Folium Citri tangerinae 40-80, Fructus Lycii 30-70, Germinatus Phragmitis 50-80, Ganoderma 20-70, Agkistrodon halys 40-70, Fructus Citri Sarcodactylis 50-80.
Further; Be used for that stagnation of QI body constitution, phlegm-dampness constitution people circulation of qi promoting are invigorated blood circulation, the Chinese medicine preparation of hard masses softening and resolving, its active ingredient is processed by the crude drug of following mass fraction: Semen Persicae 30-50, Semen Sinapis 35-45, Thallus Laminariae (Thallus Eckloniae) 50-60, Concha Ostreae 40-60, Herba Taraxaci 40-70, Fructus Hordei Germinatus 45-55, Radix Glycyrrhizae 40-60, Endothelium Corneum Gigeriae Galli 40-60, CitrusaurantiumL.Var.amara Engl. 20-30, tangerine 20-30, Vascular aurantii 30-50, Semen Citri Reticulatae 40-70, Folium Citri tangerinae 50-70, Fructus Lycii 40-60, Germinatus Phragmitis 60-70, Ganoderma 30-60, Agkistrodon halys 50-60, Fructus Citri Sarcodactylis 60-70.
Further; Be used for that stagnation of QI body constitution, phlegm-dampness constitution people circulation of qi promoting are invigorated blood circulation, the Chinese medicine preparation of hard masses softening and resolving, its active ingredient is processed by the crude drug of following mass fraction: Semen Persicae 40, Semen Sinapis 40, Thallus Laminariae (Thallus Eckloniae) 55, Concha Ostreae 50, Herba Taraxaci 50, Fructus Hordei Germinatus 50, Radix Glycyrrhizae 50, Endothelium Corneum Gigeriae Galli 50, CitrusaurantiumL.Var.amara Engl. 25, tangerine 25, Vascular aurantii 40, Semen Citri Reticulatae 50, Folium Citri tangerinae 60, Fructus Lycii 50, Germinatus Phragmitis 65, Ganoderma 50, Agkistrodon halys 55, Fructus Citri Sarcodactylis 65.
Saidly be used for that stagnation of QI body constitution, phlegm-dampness constitution people circulation of qi promoting are invigorated blood circulation, the Chinese medicine preparation of hard masses softening and resolving is granule, tablet, capsule, pill or syrup.
Provided by the inventionly be used for that stagnation of QI body constitution, phlegm-dampness constitution people circulation of qi promoting are invigorated blood circulation, the Chinese medicine preparation method for preparing of hard masses softening and resolving, may further comprise the steps:
A10, by said mass fraction get 18 the flavor crude drug, Semen Persicae 20-60, Semen Sinapis 30-50, Thallus Laminariae (Thallus Eckloniae) 40-70, Concha Ostreae 20-70, Herba Taraxaci 30-80, Fructus Hordei Germinatus 40-60, Radix Glycyrrhizae 30-70, Endothelium Corneum Gigeriae Galli 30-70, CitrusaurantiumL.Var.amara Engl. 10-40, tangerine 10-40, Vascular aurantii 20-60, Semen Citri Reticulatae 30-80, Folium Citri tangerinae 40-80, Fructus Lycii 30-70, Germinatus Phragmitis 50-80, Ganoderma 20-70, Agkistrodon halys 40-70, Fructus Citri Sarcodactylis 50-80;
A20, the pallas pit viper powder of half quality is broken into the Agkistrodon halys powder and crosses 40 mesh sieves, use radiation sterilizing, obtain aseptic Agkistrodon halys powder, remaining crude drug was with drinking water immersion 0.5-1.0 hour;
A30, soaked above-mentioned raw materials medicine is decocted three times, add 6 times of amounts of water, 5 times of amounts, 5 times of amounts at every turn respectively, decocted 1-1.5 hour at every turn, filter the medicinal liquid of collecting each decoction acquisition respectively;
It is 1.2-1.3/50 ℃ clear paste that A40, the said medicinal liquid that will collect are concentrated into proportion;
A50, with said clear paste and said aseptic Agkistrodon halys powder uniform mixing, vacuum drying becomes dried cream;
A60, with broken mistake 80 mesh sieves of said dried cream powder, add corresponding auxiliary material and process corresponding Chinese medicine preparation.
In said method, said adjuvant is one or more in binding agent, filler, correctives, wetting agent, antiseptic, the antioxidant.
Provided by the inventionly be used for that stagnation of QI body constitution, phlegm-dampness constitution people circulation of qi promoting are invigorated blood circulation, the Chinese medicine preparation of hard masses softening and resolving; Adopt the medicinal and edible plant compatibility; Has no side effect; Can effectively alleviate or eliminate ill symptomses such as stagnation of QI body constitution, phlegm-dampness constitution crowd cyclomastopathy, distending pain of the breast, distention and pain of breast before menstruation, and have no side effect.
The specific embodiment
Make detailed explanation below in conjunction with specific embodiment the present invention.
Primary raw material of the present invention is Semen Persicae, Semen Sinapis, Thallus Laminariae (Thallus Eckloniae), Concha Ostreae, Herba Taraxaci, Fructus Hordei Germinatus, Radix Glycyrrhizae, Endothelium Corneum Gigeriae Galli, CitrusaurantiumL.Var.amara Engl., dried tangerine peel, Vascular aurantii, Semen Citri Reticulatae, Folium Citri tangerinae, Fructus Lycii, Germinatus Phragmitis, Ganoderma, Agkistrodon halys, Fructus Citri Sarcodactylis.
Semen Persicae: bitter but sweet flavor and property are flat, GUIXIN, liver, large intestine channel, and the blood circulation promoting and blood stasis dispelling effect is very wide, availablely controls the various worn-out diseases of stagnation of blood stasis.
Semen Sinapis: warm in nature, acrid in the mouth has the effect of lung moistening eliminating phlegm, reducing swelling and alleviating pain.
Thallus Laminariae (Thallus Eckloniae): salty in the mouth, cold in nature, return liver, stomach, kidney channel, cure mainly hard masses softening and resolving, expectorant, diuretic.Be used for goiter, scrofula, painful and swollen testis, phlegm retention edema.
Concha Ostreae: salty in the mouth, cold nature is returned liver, gallbladder, kidney channel.Belong to suppressing the hyperactive liver to relieve the wind syndrome, yin-nourishing drug.
Herba Taraxaci: sweet in the mouth, little hardship, cold in nature.Cure mainly heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.
Fructus Hordei Germinatus: sweet in the mouth, property is flat, returns spleen, stomach warp.Cure mainly promote qi circulation digestion promoting, spleen benefiting and stimulating the appetite moves back newborn relieving distension.Be used for food stagnation and do not disappear, abdominal distention, insufficiency of the spleen lack of appetite, newborn antiperspirant smoulders, distending pain of the breast, women's ablactation, Fructus Hordei Germinatus invigorating the spleen and regulating the stomach lactogenesis.
Radix Glycyrrhizae: sweet in the mouth, return 12 warps.Cure mainly invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain.Be used for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Endothelium Corneum Gigeriae Galli: sweet in the mouth, cold in nature, return spleen, stomach, small intestinal, urinary bladder channel.Cure mainly promoting digestion and invigorating the stomach, arresting seminal emission.
CitrusaurantiumL.Var.amara Engl.: bitter in the mouth, acid, cold nature.Cure mainly promoting the circulation of QI to alleviate the stagnation in middle-JIAO, help digestion, reduce phlegm.Be used for the vexed distending pain of breast abdomen, accumulation of food in the stomach and intes tine due to indigestion, phlegm retention, proctoptosis.
Tangerine: acrid in the mouth, hardship, warm in nature, return lung, spleen channel.Cure mainly cold expelling, dampness, promoting the circulation of QI, expectorant.Be used for the cough due to wind and cold, the itching of the throat abundant expectoration, food stagnation is got sick from drinking too much wine, and the vomiting and nausea painful abdominal mass is vexed.
Vascular aurantii: sweet in the mouth, hardship, property is flat, returns liver,kidney,spleen, stomach warp.Cure mainly anticancer, the activating QI to eliminate phlegm that relieves internal heat.
Semen Citri Reticulatae: bitter in the mouth, property is flat, returns liver, kidney channel.Cure mainly and regulate the flow of vital energy, pain relieving.Be used to control hernia, painful and swollen testis, acute mastitis, lumbago, colicky pain of bladder.
Folium Citri tangerinae: bitter in the mouth, property is flat.Cure mainly soothing the liverly, circulation of qi promoting is reduced phlegm, the detumescence poison.Be used for hypochondriac pain, acute mastitis, lung abscess, cough, chest and diaphragm feeling of fullness, hernia.
Fructus Lycii: sweet in the mouth, property is flat, returns liver, kidney, warp.Cure mainly nourishing the liver, nourishing kidney, lung moistening.Be used for caused by liver and kidney deficiency, have a dizzy spell, visual one clear, soreness of the waist and knees, impotence and seminal emission, cough due to consumptive disease, the taking fluids profusely of quenching one's thirst.
Germinatus Phragmitis: sweet in the mouth, hardship, tepor cold in nature attaches to the lung and stomach meridians.Cure mainly heat-clearing and toxic substances removing, diuretic promotes the production of body fluid.
Ganoderma: sweet in the mouth, property is flat, GUIXIN, lung, liver, kidney channel.Cure mainly asthenia, cough, asthma, insomnia, dyspepsia, malignant tumor etc.
Agkistrodon halys: return spleen, Liver Channel.Cure mainly dispel the wind, collateral dredging, pain relieving, detoxifcation, rheumatic arthralgia, leprosy, scrofula, furuncle, scabies, haemorrhoids, tumor.
Fructus Citri Sarcodactylis: acrid in the mouth, hardship, sweet, warm in nature, return liver, spleen, stomach warp, activating QI to eliminate phlegm, preventing or arresting vomiting relieving distension, the liver soothing and the spleen invigorating, the more kinds of medicinal functions of stomach function regulating are arranged.
Below give an example and provided by the inventionly be used for that stagnation of QI body constitution, phlegm-dampness constitution people circulation of qi promoting are invigorated blood circulation, several kinds of specific embodiments of the Chinese medicine preparation of hard masses softening and resolving:
Embodiment 1:
Be used for that stagnation of QI body constitution, phlegm-dampness constitution people circulation of qi promoting are invigorated blood circulation, the Chinese medicine preparation of hard masses softening and resolving, its active ingredient comprises the crude drug of following mass fraction: Semen Persicae 60, Semen Sinapis 40, Thallus Laminariae (Thallus Eckloniae) 70, Concha Ostreae 40, Herba Taraxaci 40, Fructus Hordei Germinatus 60, Radix Glycyrrhizae 30, Endothelium Corneum Gigeriae Galli 50, CitrusaurantiumL.Var.amara Engl. 10, tangerine 20, Vascular aurantii 60, Semen Citri Reticulatae 70, Folium Citri tangerinae 40, Fructus Lycii 45, Germinatus Phragmitis 75, Ganoderma 70, Agkistrodon halys 40, Fructus Citri Sarcodactylis 50.
Embodiment 2:
Be used for that stagnation of QI body constitution, phlegm-dampness constitution people circulation of qi promoting are invigorated blood circulation, the Chinese medicine preparation of hard masses softening and resolving, its active ingredient comprises the crude drug of following mass fraction: Semen Persicae 30, Semen Sinapis 45, Thallus Laminariae (Thallus Eckloniae) 40, Concha Ostreae 60, Herba Taraxaci 60, Fructus Hordei Germinatus 45, Radix Glycyrrhizae 55, Endothelium Corneum Gigeriae Galli 70, CitrusaurantiumL.Var.amara Engl. 20, tangerine 10, Vascular aurantii 50, Semen Citri Reticulatae 60, Folium Citri tangerinae 50, Fructus Lycii 70, Germinatus Phragmitis 65, Ganoderma 30, Agkistrodon halys 50, Fructus Citri Sarcodactylis 60.
Embodiment 3:
Be used for that stagnation of QI body constitution, phlegm-dampness constitution people circulation of qi promoting are invigorated blood circulation, the Chinese medicine preparation of hard masses softening and resolving, its active ingredient comprises the crude drug of following mass fraction: Semen Persicae 20, Semen Sinapis 50, Thallus Laminariae (Thallus Eckloniae) 50, Concha Ostreae 30, Herba Taraxaci 70, Fructus Hordei Germinatus 55, Radix Glycyrrhizae 60, Endothelium Corneum Gigeriae Galli 60, CitrusaurantiumL.Var.amara Engl. 30, tangerine 30, Vascular aurantii 30, Semen Citri Reticulatae 30, Folium Citri tangerinae 80, Fructus Lycii 60, Germinatus Phragmitis 80, Ganoderma 20, Agkistrodon halys 60, Fructus Citri Sarcodactylis 55.
Embodiment 4:
Be used for that stagnation of QI body constitution, phlegm-dampness constitution people circulation of qi promoting are invigorated blood circulation, the Chinese medicine preparation of hard masses softening and resolving, its active ingredient comprises the crude drug of following mass fraction: Semen Persicae 40, Semen Sinapis 40, Thallus Laminariae (Thallus Eckloniae) 55, Concha Ostreae 50, Herba Taraxaci 50, Fructus Hordei Germinatus 50, Radix Glycyrrhizae 50, Endothelium Corneum Gigeriae Galli 50, CitrusaurantiumL.Var.amara Engl. 25, tangerine 25, Vascular aurantii 40, Semen Citri Reticulatae 50, Folium Citri tangerinae 60, Fructus Lycii 50, Germinatus Phragmitis 65, Ganoderma 50, Agkistrodon halys 55, Fructus Citri Sarcodactylis 65.
Embodiment 5:
Be used for that stagnation of QI body constitution, phlegm-dampness constitution people circulation of qi promoting are invigorated blood circulation, the Chinese medicine preparation of hard masses softening and resolving, its active ingredient comprises the crude drug of following mass fraction: Semen Persicae 50, Semen Sinapis 35, Thallus Laminariae (Thallus Eckloniae) 60, Concha Ostreae 20, Herba Taraxaci 80, Fructus Hordei Germinatus 40, Radix Glycyrrhizae 40, Endothelium Corneum Gigeriae Galli 30, CitrusaurantiumL.Var.amara Engl. 40, tangerine 20, Vascular aurantii 55, Semen Citri Reticulatae 40, Folium Citri tangerinae 70, Fructus Lycii 30, Germinatus Phragmitis 60, Ganoderma 60, Agkistrodon halys 70, Fructus Citri Sarcodactylis 70.
Embodiment 6:
Be used for that stagnation of QI body constitution, phlegm-dampness constitution people circulation of qi promoting are invigorated blood circulation, the Chinese medicine preparation of hard masses softening and resolving, its active ingredient comprises the crude drug of following mass fraction: Semen Persicae 40, Semen Sinapis 30, Thallus Laminariae (Thallus Eckloniae) 45, Concha Ostreae 70, Herba Taraxaci 30, Fructus Hordei Germinatus 45, Radix Glycyrrhizae 70, Endothelium Corneum Gigeriae Galli 40, CitrusaurantiumL.Var.amara Engl. 50, tangerine 40, Vascular aurantii 20, Semen Citri Reticulatae 80, Folium Citri tangerinae 55, Fructus Lycii 40, Germinatus Phragmitis 50, Ganoderma 40, Agkistrodon halys 45, Fructus Citri Sarcodactylis 80.
Above-mentioned six kinds of embodiment are merely provided by the invention and are used for that stagnation of QI body constitution, phlegm-dampness constitution people circulation of qi promoting are invigorated blood circulation, several kinds of preferable specific embodiments of Chinese medicine preparation of hard masses softening and resolving, wherein, and embodiment 4 best results.But the present invention is not limited to above-mentioned six kinds of concrete embodiment, as long as the quality proportioning of crude drug satisfies following requirement, all can reach effect of the present invention.Be provided by the inventionly to be used for that stagnation of QI body constitution, phlegm-dampness constitution people circulation of qi promoting are invigorated blood circulation, the Chinese medicine preparation of hard masses softening and resolving, its active ingredient comprises the crude drug of following mass fraction: Semen Persicae 20-60, Semen Sinapis 30-50, Thallus Laminariae (Thallus Eckloniae) 40-70, Concha Ostreae 20-70, Herba Taraxaci 30-80, Fructus Hordei Germinatus 40-60, Radix Glycyrrhizae 30-70, Endothelium Corneum Gigeriae Galli 30-70, CitrusaurantiumL.Var.amara Engl. 10-40, tangerine 10-40, Vascular aurantii 20-60, Semen Citri Reticulatae 30-80, Folium Citri tangerinae 40-80, Fructus Lycii 30-70, Germinatus Phragmitis 50-80, Ganoderma 20-70, Agkistrodon halys 40-70, Fructus Citri Sarcodactylis 50-80.
The present invention also provides above-mentioned and has been used for that stagnation of QI body constitution, phlegm-dampness constitution people circulation of qi promoting are invigorated blood circulation, the method for preparing of the Chinese medicine preparation of hard masses softening and resolving, may further comprise the steps:
A10, according to following mass fraction get 18 the flavor crude drug: Semen Persicae 20-60, Semen Sinapis 30-50, Thallus Laminariae (Thallus Eckloniae) 40-70, Concha Ostreae 20-70, Herba Taraxaci 30-80, Fructus Hordei Germinatus 40-60, Radix Glycyrrhizae 30-70, Endothelium Corneum Gigeriae Galli 30-70, CitrusaurantiumL.Var.amara Engl. 10-40, tangerine 10-40, Vascular aurantii 20-60, Semen Citri Reticulatae 30-80, Folium Citri tangerinae 40-80, Fructus Lycii 30-70, Germinatus Phragmitis 50-80, Ganoderma 20-70, Agkistrodon halys 40-70, Fructus Citri Sarcodactylis 50-80;
A20, the pallas pit viper powder of half quality is broken into the Agkistrodon halys powder and crosses 40 mesh sieves, use radiation sterilizing, obtain aseptic Agkistrodon halys powder, remaining crude drug (comprising remaining Agkistrodon halys) was with drinking water immersion 0.5-1.0 hour;
A30, soaked above-mentioned raw materials medicine is decocted three times, collect and decoct the medicinal liquid that obtains.Specifically, at first add the drinking water of 6 times of amounts, decocted 1-1.5 hour, filter and obtain medicinal liquid for the first time; The drinking water that crude drug after the filtration adds 5 times of amounts again decocted 1-1.5 hour, filtered once more to obtain medicinal liquid for the second time; The drinking water that crude drug after filtering once more adds 5 times of amounts again decocted 1-1.5 hour, filtered and obtained medicinal liquid for the third time; Collect first, second, third time medicinal liquid;
A40, be 1.2-1.3/50 ℃ clear paste with being concentrated into proportion after the first time, second time and the medicinal liquid mixing for the third time that decoct to obtain for three times;
A50, with said clear paste and said aseptic Agkistrodon halys powder uniform mixing, vacuum drying becomes dried cream;
A60, with broken mistake 80 mesh sieves of said dried cream powder, add the Chinese medicine preparation that corresponding auxiliary material is processed corresponding granule, tablet, capsule, pill or syrup dosage form.
Existing preparation process is adopted in the preparation of various dosage forms.As:
(1), the method for preparing of capsule is following:
Dried cream after pulverizing is added gross weight 3.5% silicon dioxide, and mix homogeneously is packed into capsule.
(2), the method for preparing of tablet is following:
Dried cream after pulverizing is added an amount of adjuvant, and like granulations such as binding agent, correctives, antiseptic, antioxidant, dry, tabletting, film coating is processed tablet then.
(3), the method for preparing of the watered pill is following:
The crushed dry paste adding an appropriate amount of excipients, such as binders, flavoring agents, preservatives, antioxidants, other co Outflow Rate Nearby Inclined, sterilization, pill, polishing the form of tablets, wherein the lighting requirements for 2 hours.
(4), the method for preparing of granule is following:
Dried cream after pulverizing is added an amount of adjuvant, process granule like granulation, dryings such as binding agent, correctives, antiseptic, antioxidants, wherein dry back moisture must not surpass 5%.
Provided by the inventionly be used for that stagnation of QI body constitution, phlegm-dampness constitution people circulation of qi promoting are invigorated blood circulation, stagnation of QI body constitution, phlegm-dampness constitution people's negative characteristics can effectively alleviated or eliminate to the Chinese medicine preparation of hard masses softening and resolving, provide the treatment experimental data of several kinds of classical symptoms to explain below:
(1), cyclomastopathy, distending pain of the breast.
1, experimental technique:
1.1 experimental group is taken capsule provided by the invention, 2 times on the one, one time 3, routing motion therapy and dietetic therapy; Matched group is taken the medicine routing motion therapy and the dietetic therapy of promoting flow of QI and blood, hard masses softening and resolving.Two groups equal 30 days be 1 course of treatment, finish back evaluation curative effect the course of treatment.
1.2 comparability inspection before the treatment.
1.2.1 as shown in table 1, the age distributional difference does not have significance before experimental group and the treatment of control group.
Age distribution before the table 1 liang group treatment
More than each the group through X
2Check, difference that there are no significant.
1.2.2 the sick there was no significant difference of planting before experimental group and the treatment of control group.
2, criterion of therapeutical effect and assessment method:
Mark according to items such as symptom, sign, meridians detection inspections.Produce effects: fundamental symptoms disappears, and it is shown in green through, tri-jiao channel index that meridians detect inspection Liver Channel, stomach, is tending towards normal; Effectively: fundamental symptoms obviously improves, and meridians detect checks that Liver Channel, stomach warp, tri-jiao channel index are shown as indigo plant, yellow; Invalid: fundamental symptoms does not change, and it is shown in red through, tri-jiao channel index that meridians detect inspection Liver Channel, stomach.
3, therapeutic outcome.
3.1 total effects is relatively seen table 2 between group, the Ridit assay shows that total effects has significant difference between matched group and treatment group, and the experimental group total effective rate is 81.3%, obviously is superior to matched group 52.0%, and prompting experimental group curative effect is better.
Total effects relatively between table 2 group
(2), distention and pain of breast before menstruation.
1, experimental technique:
1.1 experimental group is taken capsule provided by the invention, 2 times on the one, one time 3, routing motion therapy and dietetic therapy; Matched group is normally taken promoting flow of QI and blood, hard masses softening and resolving medicine.Two groups equal 15 days be 1 course of treatment, finish back evaluation curative effect the course of treatment.
1.2 comparability inspection before the treatment.
1.2.1 as shown in table 3, the age distributional difference does not have significance before experimental group and the treatment of control group.
Age distribution before the table 3 liang group treatment
More than each the group through X
2Check, difference that there are no significant.
1.2.2 the sick there was no significant difference of planting before experimental group and the treatment of control group.
More than each the group through X
2Check, difference that there are no significant.
2, criterion of therapeutical effect and assessment method.
Mark according to items such as symptom, sign, blood pressure tests.Produce effects: fundamental symptoms disappears, and it is shown in green through, tri-jiao channel index that meridians detect inspection Liver Channel, stomach, is tending towards normal; Effectively: fundamental symptoms obviously improves, and meridians detect checks that Liver Channel, stomach warp, tri-jiao channel index are shown as indigo plant, yellow; Invalid: fundamental symptoms does not change, and it is shown in red through, tri-jiao channel index that meridians detect inspection Liver Channel, stomach.
3, therapeutic outcome.
3.1 total effects is relatively seen table 4 between group, the Ridit assay shows that total effects has significant difference between matched group and treatment group, and treatment group total effective rate is 89.3%, matched group 53.0%, and prompting experimental group curative effect is better.
Total effects relatively between table 4 group
The present invention is not limited to above-mentioned preferred forms, and anyone should learn the structural change of under enlightenment of the present invention, making, and every have identical or close technical scheme with the present invention, all falls within protection scope of the present invention.
Claims (6)
1. be used for that stagnation of QI body constitution, phlegm-dampness constitution people circulation of qi promoting are invigorated blood circulation, the Chinese medicine preparation of hard masses softening and resolving; It is characterized in that the active ingredient of this Chinese medicine preparation is processed by the crude drug of following mass fraction: Semen Persicae 20-60, Semen Sinapis 30-50, Thallus Laminariae (Thallus Eckloniae) 40-70, Concha Ostreae 20-70, Herba Taraxaci 30-80, Fructus Hordei Germinatus 40-60, Radix Glycyrrhizae 30-70, Endothelium Corneum Gigeriae Galli 30-70, CitrusaurantiumL.Var.amara Engl. 10-40, tangerine 10-40, Vascular aurantii 20-60, Semen Citri Reticulatae 30-80, Folium Citri tangerinae 40-80, Fructus Lycii 30-70, Germinatus Phragmitis 50-80, Ganoderma 20-70, Agkistrodon halys 40-70, Fructus Citri Sarcodactylis 50-80.
2. as claimed in claim 1ly be used for that stagnation of QI body constitution, phlegm-dampness constitution people circulation of qi promoting are invigorated blood circulation, the Chinese medicine preparation of hard masses softening and resolving; It is characterized in that the active ingredient of this Chinese medicine preparation is processed by the crude drug of following mass fraction: Semen Persicae 30-50, Semen Sinapis 35-45, Thallus Laminariae (Thallus Eckloniae) 50-60, Concha Ostreae 40-60, Herba Taraxaci 40-70, Fructus Hordei Germinatus 45-55, Radix Glycyrrhizae 40-60, Endothelium Corneum Gigeriae Galli 40-60, CitrusaurantiumL.Var.amara Engl. 20-30, tangerine 20-30, Vascular aurantii 30-50, Semen Citri Reticulatae 40-70, Folium Citri tangerinae 50-70, Fructus Lycii 40-60, Germinatus Phragmitis 60-70, Ganoderma 30-60, Agkistrodon halys 50-60, Fructus Citri Sarcodactylis 60-70.
3. as claimed in claim 1ly be used for that stagnation of QI body constitution, phlegm-dampness constitution people circulation of qi promoting are invigorated blood circulation, the Chinese medicine preparation of hard masses softening and resolving; It is characterized in that the active ingredient of this Chinese medicine preparation is processed by the crude drug of following mass fraction: Semen Persicae 40, Semen Sinapis 40, Thallus Laminariae (Thallus Eckloniae) 55, Concha Ostreae 50, Herba Taraxaci 50, Fructus Hordei Germinatus 50, Radix Glycyrrhizae 50, Endothelium Corneum Gigeriae Galli 50, CitrusaurantiumL.Var.amara Engl. 25, dried tangerine peel 25, Vascular aurantii 40, Semen Citri Reticulatae 50, Folium Citri tangerinae 60, Fructus Lycii 50, Germinatus Phragmitis 65, Ganoderma 50, Agkistrodon halys 55, Fructus Citri Sarcodactylis 65.
4. be used for as claim 1 to 3 each claim is described that stagnation of QI body constitution, phlegm-dampness constitution people circulation of qi promoting are invigorated blood circulation, the Chinese medicine preparation of hard masses softening and resolving, it is characterized in that this Chinese medicine preparation is granule, tablet, capsule, pill or syrup.
5. the method for preparing of Chinese medicine preparation as claimed in claim 4 is characterized in that may further comprise the steps:
A10, by said mass fraction get 18 the flavor crude drug, Semen Persicae 20-60, Semen Sinapis 30-50, Thallus Laminariae (Thallus Eckloniae) 40-70, Concha Ostreae 20-70, Herba Taraxaci 30-80, Fructus Hordei Germinatus 40-60, Radix Glycyrrhizae 30-70, Endothelium Corneum Gigeriae Galli 30-70, CitrusaurantiumL.Var.amara Engl. 10-40, tangerine 10-40, Vascular aurantii 20-60, Semen Citri Reticulatae 30-80, Folium Citri tangerinae 40-80, Fructus Lycii 30-70, Germinatus Phragmitis 50-80, Ganoderma 20-70, Agkistrodon halys 40-70, Fructus Citri Sarcodactylis 50-80;
A20, the pallas pit viper powder of half quality is broken into the Agkistrodon halys powder and crosses 40 mesh sieves, use radiation sterilizing, obtain aseptic Agkistrodon halys powder, remaining crude drug was with drinking water immersion 0.5-1.0 hour;
A30, soaked above-mentioned raw materials medicine is decocted three times, add 6 times of amounts of water, 5 times of amounts, 5 times of amounts at every turn respectively, decocted 1-1.5 hour at every turn, filter the medicinal liquid of collecting each decoction acquisition respectively;
It is 1.2-1.3/50 ℃ clear paste that A40, the said medicinal liquid that will collect are concentrated into proportion;
A50, with said clear paste and said aseptic Agkistrodon halys powder uniform mixing, vacuum drying becomes dried cream;
A60, with broken mistake 80 mesh sieves of said dried cream powder, add corresponding auxiliary material and process corresponding Chinese medicine preparation.
6. the method for preparing of Chinese medicine preparation as claimed in claim 5 is characterized in that, said adjuvant is one or more in binding agent, filler, correctives, wetting agent, antiseptic, the antioxidant.
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| 党毅，等.中国保健食品的现状及展望.《北京中医药大学学报》.1998,第21卷(第5期),8－9. * |
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