The specific embodiment
Make detailed explanation below in conjunction with specific embodiment the present invention.
Primary raw material of the present invention is Herba Pogostemonis, the Radix Angelicae Dahuricae, Radix Puerariae, fresh Rhizoma Imperatae, Poria, Fructus Crataegi, Herba Portulacae, Pericarpium Citri tangerinae, Fructus Mume and Fructus Chaenomelis, wherein:
Herba Pogostemonis: acrid in the mouth, slightly warm in nature is returned lung, spleen, stomach.Function: dispelling summer-heat from superficies of the body, removing dampness to restore normal function of the stomach.Be used for the summertime flu, the cold and heat headache, breast gastral cavity painful abdominal mass is vexed, and vomiting is had loose bowels. nasal sinusitis, tinea manus and pedis.
The Radix Angelicae Dahuricae: acrid in the mouth, warm in nature, return lung, spleen, stomach, function: expelling wind and removing dampness, understand things pain-stopping, detumescence and apocenosis is used for headache due to common cold, and superciliary ridge is painful, toothache, nasal obstruction, nasal sinusitis, wet chronic diarrhea, women leucorrhea, the ulcer sores contained.
Radix Puerariae: sweet in the mouth is hot, and property is flat, returns taste, function: expelling pathogenic factors from muscles for reducing heat, deliver rash, and be used for fever caused by exogenous pathogens, rigidity pain on the head and nape, measles goes out not smooth from the beginning of, rash, and epidemic febrile disease is thirsty, and diabetes is had loose bowels, dysentery, hypertension, coronary heart disease, damp eliminating.
Fresh Rhizoma Imperatae: sweet in the mouth, cold in nature, return lung stomach, the heart, bladder, function: cooling blood and relieving pain, clearing away heat and promoting production of body fluid, inducing diuresis for treating stranguria syndrome, it is hemorrhage to be used for heat in blood, calentura excessive thirst, gastric heat vomiting, dyspnea and cough due to lung-heat, the puckery pain of dribbling urination, edema, jaundice.
Poria: slightly sweet flavor, property is flat, GUIXIN spleen kidney lung, function: promoting diuresis to eliminate damp pathogen, invigorating the spleen and regulating the stomach, mind tranquilizing and the heart calming is used for dysuria, the edema distension, phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite is had loose bowels, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine.
Fructus Crataegi: sour in the mouth is sweet, and slightly warm in nature is returned the taste liver, function: it is long-pending to help digestion, and blood stasis dispelling stagnates, and is used for eating accumulation, abdominal distention, dysentery, dysmenorrhea due to blood stasis, hernia or painful and swollen testis, hyperlipemia.
Herba Portulacae: acrid in the mouth, hardship, cold in nature, return large intestine, liver, spleen three warps.Function: heat-clearing and toxic substances removing, the blood detumescence of loosing.Be used for the hematodiarrhoea pus and blood, pyretic stranguria, stranguria with blood, leukorrhagia, carbuncle malignant boil, erysipelas, trace scrofula.Also be used to have blood in stool, metrorrhagia, anastalsis is arranged.
Pericarpium Citri tangerinae: acrid in the mouth, hardship, warm in nature, return spleen, lung meridian.Function: regulate the flow of vital energy in the accent, drying dampness to eliminate phlegm is used to treat stagnation of QI in spleen and stomach, distension and fullness in the abdomen, vomiting, or uncomfortable in chest due to the turbid damp obstructing in middle-JIAO, indigestion and loss of appetite, loose stool.
Fructus Mume: sour in the mouth, puckery, property is flat, returns liver, spleen, lung, large intestine channel.Function: astringe the lung, astringing intestine to stop diarrhea promotes the production of body fluid, relieving colic caused by ascaris.Be used for chronic cough of deficiency lung, the chronic dysentery laxation, deficiency-heat is quenched one's thirst, ascariasis of biliary tract vomiting stomachache, ascariasis of biliary tract.
Fructus Chaenomelis: sweet in the mouth, property is put down, is slightly cold, and returns liver, spleen channel.Function: can also relieve summer heat after aid digestion quench one's thirst, nourishing the lung to arrest cough.Its distinctive Fructus Chaenomelis ferment can clearing away heart-fire and moistening the lung can also facilitating digestion, control gastropathy, its exclusive Fructus Chaenomelis alkali has antitumor efficacy, and the lymphoid leukemia cell is had strong active anticancer.
Therefore, above-mentioned compatibility is formed and is met differential diagnosis in tcm thought, adopts the medicinal and edible plant compatibility, has no side effect.
Several kinds of specific embodiments that are used for the Chinese medicine preparation of damp and hot body constitution people's damp eliminating removing dampness provided by the invention of below giving an example:
Embodiment 1:
The Chinese medicine preparation that is used for damp and hot body constitution people's damp eliminating removing dampness, its active ingredient comprise the crude drug (among each embodiment all the unit's of omission kilogram) of following mass fraction: Herba Pogostemonis 40, the Radix Angelicae Dahuricae 110, Radix Puerariae 60, fresh Rhizoma Imperatae 40, Poria 40, Fructus Crataegi 130, Herba Portulacae 40, Pericarpium Citri tangerinae 45, Fructus Mume 60, Fructus Chaenomelis 50.
Embodiment 2:
Be used for the Chinese medicine preparation of damp and hot body constitution people's damp eliminating removing dampness, its active ingredient comprises the crude drug of following mass fraction: Herba Pogostemonis 40, the Radix Angelicae Dahuricae: 120, Radix Puerariae: 85, fresh Rhizoma Imperatae: 70, Poria: 30, Fructus Crataegi: 70, Herba Portulacae 80, Pericarpium Citri tangerinae 30, Fructus Mume 40, Fructus Chaenomelis 55.
Embodiment 3:
Be used for the Chinese medicine preparation of damp and hot body constitution people's damp eliminating removing dampness, its active ingredient comprises the crude drug of following mass fraction: Herba Pogostemonis: 45, the Radix Angelicae Dahuricae: 80, Radix Puerariae: 110, fresh Rhizoma Imperatae: 60, Poria: 60, Fructus Crataegi: 85, Herba Portulacae 50, Pericarpium Citri tangerinae 20, Fructus Mume 50, Fructus Chaenomelis 60.
Embodiment 4:
Be used for the Chinese medicine preparation of damp and hot body constitution people's damp eliminating removing dampness, its active ingredient comprises the crude drug of following mass fraction: Herba Pogostemonis: 50, the Radix Angelicae Dahuricae: 90, Radix Puerariae: 80, fresh Rhizoma Imperatae: 50, Poria: 60, Fructus Crataegi: 95, Herba Portulacae 60, Pericarpium Citri tangerinae 40, Fructus Mume 50, Fructus Chaenomelis 45.
Embodiment 5:
Be used for the Chinese medicine preparation of damp and hot body constitution people's damp eliminating removing dampness, its active ingredient comprises the crude drug of following mass fraction: Herba Pogostemonis: 55, the Radix Angelicae Dahuricae: 65, Radix Puerariae: 100, fresh Rhizoma Imperatae: 30, Poria: 70, Fructus Crataegi: 110, Herba Portulacae 70, Pericarpium Citri tangerinae 50, Fructus Mume 30, Fructus Chaenomelis 40.
Embodiment 6:
Be used for the Chinese medicine preparation of damp and hot body constitution people's damp eliminating removing dampness, its active ingredient comprises the crude drug of following mass fraction: Herba Pogostemonis: 60, the Radix Angelicae Dahuricae: 60, Radix Puerariae: 65, fresh Rhizoma Imperatae: 80, Poria: 80, Fructus Crataegi: 60, Herba Portulacae 55, Pericarpium Citri tangerinae 60, Fructus Mume 70, Fructus Chaenomelis 30.
Above-mentioned six kinds of embodiment are merely several kinds of preferable specific embodiments of Chinese medicine preparation that are used for damp and hot body constitution people's damp eliminating removing dampness provided by the invention, wherein, and embodiment 2 and embodiment 4 best results.But the present invention is not limited to above-mentioned six kinds of concrete embodiment, as long as the quality proportioning of crude drug satisfies following requirement, all can reach effect of the present invention.Be the Chinese medicine preparation that is used for damp and hot body constitution people's damp eliminating removing dampness provided by the invention, its active ingredient comprises the crude drug of following mass fraction: Herba Pogostemonis 40-60, Radix Angelicae Dahuricae 60-120, Radix Puerariae 60-110, fresh Rhizoma Imperatae 30-80, Poria 30-80, Fructus Crataegi 60-130, Herba Portulacae 40-80, Pericarpium Citri tangerinae 20-60, Fructus Mume 30-70, Fructus Chaenomelis 30-60.
The present invention also provides the above-mentioned method for preparing that is used for the Chinese medicine preparation of damp and hot body constitution people's damp eliminating removing dampness, may further comprise the steps:
A10, according to following mass fraction get ten the flavor crude drug: Herba Pogostemonis 40-60, Radix Angelicae Dahuricae 60-120, Radix Puerariae 60-110, fresh Rhizoma Imperatae 30-80, Poria 30-80, Fructus Crataegi 60-130, Herba Portulacae 40-80, Pericarpium Citri tangerinae 20-60, Fructus Mume 30-70, Fructus Chaenomelis 30-60;
A20, Poria is divided into two parts by quality, a copy of it is ground into Indian Bread and crosses 40 mesh sieves, uses radiation sterilizing, obtains aseptic Indian Bread; Remaining crude drug (comprising another part Poria) soaked 0.5-1.0 hour with the drinking water of 10 times of amounts;
A30, soaked above-mentioned raw materials medicine is decocted three times, collect and decoct the medicinal liquid that obtains.Specifically, at first add the drinking water of 6 times of amounts, decocted 1 hour, filter and obtain medicinal liquid for the first time; The drinking water that crude drug after the filtration adds 5 times of amounts again decocted 1 hour, filtered once more to obtain medicinal liquid for the second time; The drinking water that crude drug after filtering once more adds 5 times of amounts again decocted 1 hour, filtered and obtained medicinal liquid for the third time; Collect the volatile oil that produces in each decoction process.
A40, the first time, the second time and the post-heating of medicinal liquid mixing for the third time that decoct to obtain for three times are concentrated into proportion is 1.2-1.3/50 ℃ clear paste;
A50, with behind clear paste and the aseptic Indian Bread uniform mixing, vacuum drying becomes dried cream;
A60, with broken mistake 80 mesh sieves of dried cream powder, add the Chinese medicine preparation that the volatile oil collect and corresponding auxiliary material are processed corresponding granule, tablet, capsule, pill or syrup dosage form.
Existing preparation process is adopted in the preparation of various dosage forms.As:
(1), the method for preparing of capsule is following:
Dried cream after pulverizing is added gross weight 3.5% silicon dioxide and the volatile oil of collecting, and mix homogeneously is packed into capsule.
(2), the method for preparing of tablet is following:
Dried cream after pulverizing is added an amount of adjuvant, and like granulations such as binding agent, correctives, antiseptic, antioxidant, dry, tabletting, film coating is processed tablet then.
(3), the method for preparing of the watered pill is following:
The crushed dry paste adding an appropriate amount of excipients, such as binders, flavoring agents, preservatives, antioxidants, other co Outflow Rate Nearby Inclined, sterilization, pill, polishing the form of tablets, wherein the lighting requirements for 2 hours.
(4), the method for preparing of granule is following:
Dried cream after pulverizing is added an amount of adjuvant, process granule like granulation, dryings such as binding agent, correctives, antiseptic, antioxidants, wherein dry back moisture must not surpass 5%.
Damp and hot body constitution crowd's negative characteristics can effectively alleviated or eliminate to the capsule that is used for the damp eliminating removing dampness provided by the invention, provides the treatment experimental data of several kinds of classical symptoms to explain below:
(1), to being prone to fecula thorn, furuncle symptom.
1, experimental technique:
1.1 experimental group is taken capsule provided by the invention, 2 times on the one, one time 3, routing motion therapy and dietetic therapy; Matched group is taken dehumidifying medicine routing motion therapy and dietetic therapy.Two groups equal 30 days be 1 course of treatment, finish back evaluation curative effect the course of treatment.
1.2 comparability inspection before the treatment.
1.2.1 as shown in table 1, sex difference does not have significance before experimental group and the treatment of control group.
Sex ratio before the table 1 liang group treatment.
More than each the group through X
2Check (chi-square test), difference that there are no significant.
1.2.2 as shown in table 2, the age distributional difference does not have significance before experimental group and the treatment of control group.
Age distribution before the table 2 liang group treatment
More than each the group through X
2Check, difference that there are no significant.
1.2.3 the sick there was no significant difference of planting before experimental group and the treatment of control group.
2, criterion of therapeutical effect and assessment method:
Mark according to items such as symptom, sign, meridians detection inspections.Produce effects: fundamental symptoms disappears, and meridians detect the inspection lung meridian, the tri-jiao channel index is shown in green, are tending towards normal; Effectively: fundamental symptoms obviously improves, and meridians detect the inspection lung meridian, the tri-jiao channel index is shown as indigo plant, yellow; Invalid: fundamental symptoms does not change, and meridians detect the inspection lung meridian, the tri-jiao channel index is shown in red.
3, therapeutic outcome.
3.1 total effects is relatively seen table 4 between group, the Ridit assay shows that total effects has significant difference between matched group and treatment group, and the experimental group total effective rate is 81.3%, obviously is superior to matched group 52.0%, and prompting experimental group curative effect is better.
Total effects relatively between table 4 group
(2), to viscid not well, the urine of stool heating sense symptom being arranged.
1, experimental technique:
1.1 experimental group is taken capsule provided by the invention, 2 times on the one, one time 3, routing motion therapy and dietetic therapy; Matched group is normally taken the damp eliminating damp-resolving medicinal, like aromatic damp resolving drug.Two groups equal 15 days be 1 course of treatment, finish back evaluation curative effect the course of treatment.
1.2 comparability inspection before the treatment.
1.2.1 as shown in table 5, sex difference does not have significance before experimental group and the treatment of control group.
Sex ratio before the table 5 liang group treatment.
More than each the group through X
2Check, difference that there are no significant.
1.2.2 as shown in table 6, the age distributional difference does not have significance before experimental group and the treatment of control group.
Age distribution before the table 6 liang group treatment
More than each the group through X
2Check, difference that there are no significant.
1.2.3 the sick there was no significant difference of planting before experimental group and the treatment of control group.
More than each the group through X
2Check, difference that there are no significant.
2, criterion of therapeutical effect and assessment method.
Mark according to items such as symptom, sign, blood pressure tests.Produce effects: cardinal symptom is most of to disappear, and it is normal that the lung meridian index is recovered basically; Effectively: cardinal symptom is most of to disappear, and the three warmers index makes moderate progress; Invalid: as not meet above standard person.
3, therapeutic outcome.
3.1 total effects is relatively seen table 8 between group, the Ridit assay shows that total effects has significant difference between matched group and treatment group, and treatment group total effective rate is 89.3%, matched group 53.0%, and prompting experimental group curative effect is better.
Total effects relatively between table 8 group
(3), other symptoms.
1. clinical manifestation.
Face and nose are always glossy shinny, often feel bitter taste, halitosis or abnormal flavour is arranged in the mouth, the jaundice of urine color, the normal leucorrhea with yellow discharge of women, the always moist hyperhidrosis of males scrotum.
2. experimental technique.
2.1 experimental group is taken capsule provided by the invention, 2 times on the one, one time 2, routing motion therapy and dietetic therapy; Matched group is not taken any medicine, is not carried out any motion.Two groups equal 7 days be 1 course of treatment, finish back evaluation curative effect the course of treatment.
2.2 comparability inspection before the treatment.
2.2.1 as shown in table 9, sex difference does not have significance before experimental group and the treatment of control group.
Sex ratio before the table 9 liang group treatment
More than each the group through X
2Check, difference that there are no significant.
2.2.2 as shown in table 10, the age distributional difference does not have significance before experimental group and the treatment of control group.
Age distribution before the table 10 liang group treatment
More than each the group through X
2Check, difference that there are no significant.
2.2.3 as shown in table 11, the sick there was no significant difference of planting before experimental group and the treatment of control group.
The sick kind relatively before the table 11 liang group treatment
More than each the group through X
2Check, difference that there are no significant.
3, criterion of therapeutical effect and assessment method.
Mark according to items such as symptom, signs.Produce effects: take 3 courses of treatment of capsule, and through observing 10 days, symptom is improved obviously or eliminated; Effectively: take 3 courses of treatment of capsule, and improvement is arranged through observing 10 days symptoms; Invalid: as not meet above standard person.
4, therapeutic outcome.
4.1 total effects is relatively seen table 12 between group, the Ridit assay shows that total effects has significant difference between matched group and treatment group, and treatment group total effective rate is 85.7%, obviously is superior to matched group 53.2%, and prompting experimental group curative effect is better.
Total effects relatively between table 12 group
The analysis of comparable result shows between this group data set, physical data between each group, and no significant differences such as sex, age, the course of disease and the distribution of sick kind, comparability is better between the prompting group, and two groups have harmony.
Treatment group therapeutic efficiency is higher, and prompting treatment group curative effect is better.In addition, do not see that obvious adverse reaction takes place, explain that these article are without any side effects, safe and reliable.
The present invention is not limited to above-mentioned preferred forms, and anyone should learn the structural change of under enlightenment of the present invention, making, and every have identical or close technical scheme with the present invention, all falls within protection scope of the present invention.