CN102178840B - Chinese medicinal preparation for relieving body fluid deficiency for people with yin-deficiency physique, preparation method thereof and application thereof - Google Patents

Chinese medicinal preparation for relieving body fluid deficiency for people with yin-deficiency physique, preparation method thereof and application thereof Download PDF

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CN102178840B
CN102178840B CN2011100999229A CN201110099922A CN102178840B CN 102178840 B CN102178840 B CN 102178840B CN 2011100999229 A CN2011100999229 A CN 2011100999229A CN 201110099922 A CN201110099922 A CN 201110099922A CN 102178840 B CN102178840 B CN 102178840B
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deficiency
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semen
chinese medicine
yin
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CN102178840A (en
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陈刚
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BEIJING BODY AND MIND HEALTH INTERNATIONAL CHINESE MEDICINE RESEARCH INSTITUTE
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BEIJING BODY AND MIND HEALTH INTERNATIONAL CHINESE MEDICINE RESEARCH INSTITUTE
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Abstract

The invention discloses a Chinese medicinal preparation for relieving body fluid deficiency for people with yin-deficiency physique, a preparation method thereof and application thereof. The Chinese medicinal preparation comprises the following raw material medicaments in part by mass: 40 to 70 parts of fragrant solomonseal rhizome, 80 to 110 parts of prunus japonica thumb, 60 to 150 parts of lily, 60 to 190 parts of liquoric root, 20 to 60 parts of manyflower solomonseal rhizome, 90 to 160 parts of cinnamomvine, 80 to 170 parts of medlar, 20 to 60 parts of cassia seed, 30 to 70 parts of mulberry, 40 to 60 parts of mulberry leaf, 30 to 60 parts of chrysanthemum, 50 to 80 parts of peach seed, 40 to 70 parts of black sesame, 30 to 70 parts of citrus chirocarpus and 40 to 80 parts of platycodon root. The Chinese medicinal preparation for relieving the body fluid deficiency of the people with the yin-deficiency physique is subjected to compatibility by using plants which are homologous in medicines and food, does not have side effect, and can relieve or eliminate bad symptoms such as fever in bodies and faces, intolerance in summer-heat, skin drying, fever in palms and arches of feet, flushing or reddish check, aningeresting in eyes, dryness in mouths and throats, insomnia, constipation and the like of the people with the yin-deficiency physique effectively.

Description

Be used for deficiency of YIN body constitution people and alleviate the Chinese medicine preparation of deficiency of body fluid symptom
Technical field
The present invention relates to the field of Chinese medicines, be specifically related to be used for the Chinese medicine preparation that deficiency of YIN body constitution people is alleviated the deficiency of body fluid symptom.
Background technology
" tcm constitution " Epidemiological study that lasts 30 years, people's body constitution has nine kinds to be respectively: gentle body constitution, deficiency of YIN body constitution, damp and hot body constitution, deficiency of YIN body constitution, stagnation of QI body constitution, yang deficiency body constitution, phlegm-dampness constitution, blood stasis body constitution, allergic constitution.Wherein deficiency of YIN body constitution accounts for 8.9% of total crowd's number.
The deficiency of YIN refers to the material of internal organs storages, bodily fuctions that malnutrition causes is inharmonious, even shows the excited a series of diseases of function.The traditional Chinese medical science is often said hyperactivity of fire caused by deficiency of YIN, the empty people who is not mended, gets angry easily, can liken into chaffy dish, pot Kai Detaiwang; Be not Huo Taiwang, but the water in the pot very little, add water; When the human body deficiency of YIN; Promethean fire did not have prosperous, but the shortage of material, nutrition, so be not to reduce internal heat but want the tonifying liver YIN nourishing.The liver deficiency of YIN has the greatest impact to health.
Deficiency of YIN body constitution group characteristic:
Often sensation health, heating on the face, anti-summer-heat that can't stand summer, xerosis cutis often feels that the trick heart generates heat, buccal flushing or red partially often feels that eyes are dry and astringent, frequent dry mouth and throat, insomnia easily, often constipation with dry stool; Irascible temperament, export-oriented active, active; Build is tall and thin, be prone to suffer from cough, diabetes, amenorrhea, heating etc., is unaccommodated to the hot weather in summer at ordinary times, dry, tolerance winter, does not tolerate summer.
Various medicines in the market or health food are also not obvious to the effect of improving deficiency of YIN body constitution people ill symptoms.
Summary of the invention
Technical problem to be solved by this invention is various medicines or effect and the unconspicuous problem of health food to improving deficiency of YIN body constitution people ill symptoms that solves in the market.
In order to solve the problems of the technologies described above; The technical scheme that the present invention adopted provides and a kind ofly is used for deficiency of YIN body constitution people and alleviates Chinese medicine preparation of deficiency of body fluid symptom and preparation method thereof, and the people who provides this Chinese medicine preparation to be used for deficiency of YIN body constitution improves the application of its symptom aspect.
Provided by the inventionly be used for the Chinese medicine preparation that deficiency of YIN body constitution people is alleviated the deficiency of body fluid symptom, its active ingredient comprises the crude drug of following mass fraction: Rhizoma Polygonati Odorati 40-70, Semen Pruni 80-110, Bulbus Lilii 60-150, Radix Glycyrrhizae 60-190, Rhizoma Polygonati 20-60, Rhizoma Dioscoreae 90-160, Fructus Lycii 80-170, Semen Cassiae 20-60, Fructus Mori 30-70, Folium Mori 40-60, Flos Chrysanthemi 30-60, Semen Persicae 50-80, Semen Sesami Nigrum 40-70, Fructus Citri Sarcodactylis 30-70, Radix Platycodonis 40-80.
Further; Be used for deficiency of YIN body constitution people and alleviate the Chinese medicine preparation of deficiency of body fluid symptom, its active ingredient comprises the crude drug of following mass fraction: Rhizoma Polygonati Odorati 50-60, Semen Pruni 90-100, Bulbus Lilii 80-120, Radix Glycyrrhizae 70-110, Rhizoma Polygonati 40-50, Rhizoma Dioscoreae 100-150, Fructus Lycii 90-150, Semen Cassiae 30-50, Fructus Mori 40-60, Folium Mori 45-55, Flos Chrysanthemi 40-50, Semen Persicae 60-70, Semen Sesami Nigrum 50-60, Fructus Citri Sarcodactylis 40-60, Radix Platycodonis 50-70.
Further; Be used for deficiency of YIN body constitution people and alleviate the Chinese medicine preparation of deficiency of body fluid symptom, its active ingredient comprises the crude drug of following mass fraction: Rhizoma Polygonati Odorati 55, Semen Pruni 95, Bulbus Lilii 100, Radix Glycyrrhizae 110, Rhizoma Polygonati 45, Rhizoma Dioscoreae 130, Fructus Lycii 120, Semen Cassiae 40, Fructus Mori 50, Folium Mori 50, Flos Chrysanthemi 45, Semen Persicae 65, Semen Sesami Nigrum 55, Fructus Citri Sarcodactylis 50, Radix Platycodonis 60.
Saidly be used for deficiency of YIN body constitution people to alleviate the Chinese medicine preparation of deficiency of body fluid symptom be granule, tablet, capsule, pill or syrup.
Provided by the inventionly be used for the Chinese medicine preparation method for preparing that deficiency of YIN body constitution people is alleviated the deficiency of body fluid symptom, may further comprise the steps:
A10, get ten five tastes crude drug by following mass fraction; Rhizoma Polygonati Odorati 40-70, Semen Pruni 80-110, Bulbus Lilii 60-150, Radix Glycyrrhizae 60-190, Rhizoma Polygonati 20-60, Rhizoma Dioscoreae 90-160, Fructus Lycii 80-170, Semen Cassiae 20-60, Fructus Mori 30-70, Folium Mori 40-60, Flos Chrysanthemi 30-60, Semen Persicae 50-80, Semen Sesami Nigrum 40-70, Fructus Citri Sarcodactylis 30-70, Radix Platycodonis 40-80, the drinking water that adds 8 times of amounts of crude drug gross mass soaked 0.5-1.0 hour;
A20, decoction 1-1.5 hour are filtered and are obtained extracting solution for the first time;
The drinking water that A30, the raw material medicinal residues after will filtering add 8 times of amounts once more decocted 1-1.5 hour, filtered to obtain extracting solution for the second time;
A40, with said first time of extracting solution and after the said second time, extracting solution mixed, it is 1.25-1.3/70 ℃ clear paste that heating is concentrated into proportion;
A50, said clear paste vacuum drying is become dried cream;
A60, with broken mistake 80 mesh sieves of said dried cream powder, add corresponding auxiliary material and process corresponding Chinese medicine preparation.
In said method, said adjuvant is one or more in binding agent, filler, correctives, wetting agent, antiseptic, the antioxidant.
Provided by the inventionly be used for the Chinese medicine preparation that deficiency of YIN body constitution people is alleviated the deficiency of body fluid symptom, adopt the medicinal and edible plant compatibility, have no side effect; Can effectively alleviate or eliminate deficiency of YIN body constitution people and feel health, heating on the face, anti-summer-heat, xerosis cutis that can't stand summer often felt the heating of the trick heart, buccal flushing or red partially; Often feel that eyes are dry and astringent; Often dry mouth and throat is had a sleepless night easily, ill symptomses such as frequent constipation with dry stool.
The specific embodiment
Make detailed explanation below in conjunction with specific embodiment the present invention.
Provided by the inventionly be used for the Chinese medicine preparation that deficiency of YIN body constitution people is alleviated the deficiency of body fluid symptom; Its active ingredient mainly comprises Rhizoma Polygonati Odorati, Semen Pruni, Bulbus Lilii, Radix Glycyrrhizae, Rhizoma Polygonati, Rhizoma Dioscoreae, Fructus Lycii, Semen Cassiae, Fructus Mori, Folium Mori, Flos Chrysanthemi, Semen Persicae, Semen Sesami Nigrum, Fructus Citri Sarcodactylis, Radix Platycodonis, and compatibility is formed and met differential diagnosis in tcm thought.Wherein:
Rhizoma Polygonati Odorati: sweet in the mouth, property is flat, attaches to the lung and stomach meridians function: dry throat and mouth, the interior-heat of nourishing YIN and moistening the lung, nourishing the stomach to promote the production of body fluid, cough caused by dryness, chronic cough, the cloudy liquid consumption of calentura wounds quenched one's thirst, deficiency of YIN diseases caused by exogenous pathogenic factor, dizzy, the muscle arteries and veins spasm and pain of giddy.
Semen Pruni: acrid in the mouth, hardship, sweet, property is flat, returns spleen, large intestine, small intestine meridian, and function cures mainly: moisturize laxation, the therapeutic method to keep the adverse QI flowing downwards, diuretic.Be used for intestine-dryness due to consumption of fluid, stagnation of QI due to dyspepsia, abdominal distention constipation, edema, beriberi, dysuria.
Bulbus Lilii: sweet in the mouth, little hardship, cold nature, GUIXIN, lung meridian.Function cures mainly: nourishing YIN and moistening the lung, clearing away heart-fire for tranquillization.Be used for deficiency of YIN chronic cough, sputum mixed with blood, fidgets due to deficiency palpitation with fear, insomnia and dreamful sleep, absentminded.
Rhizoma Polygonati, sweet in the mouth, property is flat, returns spleen, lung, kidney channel, function: invigorating the spleen and replenishing QI, nourishing kidney replenishing essence.Be rich in steroidal saponin and polygonatum polysaccharide, can obviously improve the activity of superoxide dismutase in the liver (SOD), significantly reduce in the cardiac muscle lipofuscin content and can significantly improve hypoxia-bearing capability, prolong swimming time.
Radix Glycyrrhizae: sweet in the mouth, property is flat, GUIXIN, lung, spleen, stomach warp, function: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Be used for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Rhizoma Dioscoreae, sweet in the mouth, property is flat, returns spleen, lung, kidney channel, function: spleen reinforcing nourishing the stomach, the benefit of reinforcing the kidney essence.Mainly contain dioscin, vitamin, polysaccharide, have significant resisting oxygen lack, and can improve the immunity of body, simultaneously, also can prevent and treat spleen deficiency.
Fructus Lycii, sweet in the mouth, property is flat, returns liver, kidney, lung meridian, function: nourishing the liver; Nourishing kidney, lung moistening contains vitamin B1, vitamin B2, vitamin C, calcium, phosphorus, ferrum and 14 seed amino acids, improves deficiency of both the liver and kidney, has a dizzy spell; Visual unclear, soreness of the waist and knees, impotence and seminal emission, cough due to consumptive disease disappears and coughs taking fluids profusely.
Semen Cassiae, salty in the mouth is bitter, and liver, gallbladder, kidney are returned in the property Pingliang, clearing away heat to improve acuity of vision, loosening bowel to relieve constipation.Be used for the puckery pain of conjunctival congestion, the many tears of photophobia, it is dizzy to have a headache, poor vision, constipation.
Fructus Mori: sweet in the mouth, acid, cold in nature.GUIXIN, liver, kidney channel.The YIN nourishing of enriching blood is promoted the production of body fluid and is moisturized.Be used for vertigo and tinnitus, palpitation and insomnia, early whitening of beard and hair, Tianjin wound is thirsty, and interior-heat is quenched one's thirst, blood deficiency and constipation.Tonifying liver, kidney tonifying relieves dizziness, high fever, infantile convulsions, epilepsy, etc., and grows liquid.
Folium Mori: sweet in the mouth, hardship; Cold in nature.Return lung, Liver Channel.Effect: dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, suppressing liver-YANG, liver heat removing and eyesight improving, cooling blood for hemostasis.
Flos Chrysanthemi: acrid in the mouth, sweet, hardship; Cold nature.Return lung, Liver Channel.Function cures mainly: the wind heat clearing away of loosing, suppressing the hyperactive liver makes eye bright.Be used for anemopyretic cold, it is dizzy to have a headache, conjunctival congestion and swelling pain, and eyes is dim-sighted.
Semen Persicae: bitter in the mouth, sweet, property is flat.GUIXIN, liver, large intestine channel.Blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, relieving cough and asthma.Be used for amenorrhea, dysmenorrhea , WEIJIA mass in the abdomen, injury from falling down, dryness of the intestine constipation.
Semen Sesami Nigrum, sweet in the mouth, property is flat, returns liver spleen kidney; Function: the tonification liver, the benefit that nourishes blood is smart, and loosening bowel to relieve constipation contains great amount of fat and protein; Also have nutritional labelings such as saccharide, vitamin A, vitamin E, lecithin, calcium, ferrum, chromium can improve dizziness and tinnitus, the soft flaccidity of foot is soft, early whitening of beard and hair, scaly dry skin; The dryness of the intestine constipation, married woman's breast is few, carbuncle skin ulcer eczema, hemorrhoid.
Fructus Citri Sarcodactylis: acrid in the mouth, hardship, warm in nature.Return liver, spleen, lung meridian, function: liver-smoothing, qi-regulating, and stomach and alleviating pain.Cure mainly: stagnation of liver-QI and stomach-QI, distending pain in the chest and hypochondrium, gastral cavilty feeling of fullness, lack of appetite vomiting.
Radix Platycodonis: bitter in the mouth, suffering, property is flat.Effect: dispersing lung-QI and dissipating phlegm, evacuation of pus.Cure mainly and affection of exogenous wind-cold cough, abundant expectoration, pharyngalgia hoarseness, and lung abscess, retropharyngeal abscess disease such as swell and ache.
Above-mentioned compatibility is formed, and adopts the medicinal and edible plant compatibility, meets differential diagnosis in tcm thought.
Several kinds of specific embodiments that deficiency of YIN body constitution people is alleviated the Chinese medicine preparation of deficiency of body fluid symptom that are used for provided by the invention of below giving an example:
Embodiment 1:
Be used for deficiency of YIN body constitution people and alleviate the Chinese medicine preparation of deficiency of body fluid symptom, its active ingredient comprises the crude drug of following mass fraction: Rhizoma Polygonati Odorati 45, Semen Pruni 100, Bulbus Lilii 150, Radix Glycyrrhizae 60, Rhizoma Polygonati 50, Rhizoma Dioscoreae 160, Fructus Lycii 150, Semen Cassiae 20, Fructus Mori 30, Folium Mori 55, Flos Chrysanthemi 30, Semen Persicae 60, Semen Sesami Nigrum 65, Fructus Citri Sarcodactylis 55, Radix Platycodonis 40.
Embodiment 2:
Be used for deficiency of YIN body constitution people and alleviate the Chinese medicine preparation of deficiency of body fluid symptom, its active ingredient comprises the crude drug of following mass fraction: Rhizoma Polygonati Odorati 50, Semen Pruni 110, Bulbus Lilii 80, Radix Glycyrrhizae 130, Rhizoma Polygonati 60, Rhizoma Dioscoreae 150, Fructus Lycii 80, Semen Cassiae 30, Fructus Mori 40, Folium Mori 50, Flos Chrysanthemi 40, Semen Persicae 50, Semen Sesami Nigrum 50, Fructus Citri Sarcodactylis 70, Radix Platycodonis 80.
Embodiment 3:
Be used for deficiency of YIN body constitution people and alleviate the Chinese medicine preparation of deficiency of body fluid symptom, its active ingredient comprises the crude drug of following mass fraction: Rhizoma Polygonati Odorati 55, Semen Pruni 95, Bulbus Lilii 100, Radix Glycyrrhizae 110, Rhizoma Polygonati 45, Rhizoma Dioscoreae 130, Fructus Lycii 120, Semen Cassiae 40, Fructus Mori 50, Folium Mori 50, Flos Chrysanthemi 45, Semen Persicae 65, Semen Sesami Nigrum 55, Fructus Citri Sarcodactylis 50, Radix Platycodonis 60.
Embodiment 4:
Be used for deficiency of YIN body constitution people and alleviate the Chinese medicine preparation of deficiency of body fluid symptom, its active ingredient comprises the crude drug of following mass fraction: Rhizoma Polygonati Odorati 40, Semen Pruni 80, Bulbus Lilii 120, Radix Glycyrrhizae 70, Rhizoma Polygonati 40, Rhizoma Dioscoreae 140, Fructus Lycii 140, Semen Cassiae 50, Fructus Mori 60, Folium Mori 40, Flos Chrysanthemi 50, Semen Persicae 70, Semen Sesami Nigrum 40, Fructus Citri Sarcodactylis 60, Radix Platycodonis 70.
Embodiment 5:
Be used for deficiency of YIN body constitution people and alleviate the Chinese medicine preparation of deficiency of body fluid symptom, its active ingredient comprises the crude drug of following mass fraction: Rhizoma Polygonati Odorati 60, Semen Pruni 90, Bulbus Lilii 90, Radix Glycyrrhizae 150, Rhizoma Polygonati 25, Rhizoma Dioscoreae 100, Fructus Lycii 90, Semen Cassiae 60, Fructus Mori 70, Folium Mori 45, Flos Chrysanthemi 60, Semen Persicae 80, Semen Sesami Nigrum 60, Fructus Citri Sarcodactylis 40, Radix Platycodonis 50.
Embodiment 6:
Be used for deficiency of YIN body constitution people and alleviate the Chinese medicine preparation of deficiency of body fluid symptom, its active ingredient comprises the crude drug of following mass fraction: Rhizoma Polygonati Odorati 70, Semen Pruni 85, Bulbus Lilii 60, Radix Glycyrrhizae 190, Rhizoma Polygonati 20, Rhizoma Dioscoreae 90, Fructus Lycii 170, Semen Cassiae 30, Fructus Mori 40, Folium Mori 60, Flos Chrysanthemi 40, Semen Persicae 70, Semen Sesami Nigrum 70, Fructus Citri Sarcodactylis 30, Radix Platycodonis 45.
Above-mentioned six kinds of embodiment are merely several kinds of preferable specific embodiments of Chinese medicine preparation that deficiency of YIN body constitution people is alleviated the deficiency of body fluid symptom that are used for provided by the invention, wherein, and embodiment 3 best results.But the present invention is not limited to above-mentioned six kinds of concrete embodiment, as long as the quality proportioning of crude drug satisfies following requirement, all can reach effect of the present invention.Be the Chinese medicine preparation that deficiency of YIN body constitution people is alleviated the deficiency of body fluid symptom that is used for provided by the invention, its active ingredient comprises the crude drug of following mass fraction: Rhizoma Polygonati Odorati 40-70, Semen Pruni 80-110, Bulbus Lilii 60-150, Radix Glycyrrhizae 60-190, Rhizoma Polygonati 20-60, Rhizoma Dioscoreae 90-160, Fructus Lycii 80-170, Semen Cassiae 20-60, Fructus Mori 30-70, Folium Mori 40-60, Flos Chrysanthemi 30-60, Semen Persicae 50-80, Semen Sesami Nigrum 40-70, Fructus Citri Sarcodactylis 30-70, Radix Platycodonis 40-80.
The present invention also provides the above-mentioned method for preparing that deficiency of YIN body constitution people is alleviated the Chinese medicine preparation of deficiency of body fluid symptom that is used for, and may further comprise the steps:
A10, get ten five tastes crude drug by following mass fraction; Rhizoma Polygonati Odorati 40-70, Semen Pruni 80-110, Bulbus Lilii 60-150, Radix Glycyrrhizae 60-190, Rhizoma Polygonati 20-60, Rhizoma Dioscoreae 90-160, Fructus Lycii 80-170, Semen Cassiae 20-60, Fructus Mori 30-70, Folium Mori 40-60, Flos Chrysanthemi 30-60, Semen Persicae 50-80, Semen Sesami Nigrum 40-70, Fructus Citri Sarcodactylis 30-70, Radix Platycodonis 40-80, the drinking water that adds 8 times of amounts of crude drug gross mass soaked 0.5-1.0 hour;
A20, decoction 1-1.5 hour are filtered and are obtained extracting solution for the first time;
The drinking water that A30, the raw material medicinal residues after will filtering add 8 times of amounts once more decocted 1-1.5 hour, filtered to obtain extracting solution for the second time;
A40, with said first time of extracting solution and after the said second time, extracting solution mixed, it is 1.25-1.3/70 ℃ clear paste that heating is concentrated into proportion;
A50, said clear paste vacuum drying is become dried cream;
A60, with broken mistake 80 mesh sieves of said dried cream powder, add the Chinese medicine preparation that corresponding auxiliary material is processed corresponding granule, tablet, capsule, pill or syrup dosage form.
Existing preparation process is adopted in the preparation of various dosage forms.As:
(1), the method for preparing of capsule is following:
Dried cream after pulverizing is added gross weight 3.5% silicon dioxide, and mix homogeneously is packed into capsule.
(2), the method for preparing of tablet is following:
Dried cream after pulverizing is added an amount of adjuvant, and like granulations such as binding agent, correctives, antiseptic, antioxidant, dry, tabletting, film coating is processed tablet then.
(3), the method for preparing of the watered pill is following:
Dried cream after pulverizing is added an amount of adjuvant, close like binding agent, correctives, antiseptic, antioxidant etc. stick together, sterilization, pill, polishing process tablet, wherein, polishing requires 2 hours.
(4), the method for preparing of granule is following:
Dried cream after pulverizing is added an amount of adjuvant, process granule like granulation, dryings such as binding agent, correctives, antiseptic, antioxidants, wherein dry back moisture must not surpass 5%.
Provided by the inventionly be used for deficiency of YIN body constitution people and alleviate people's deficiency of body fluid symptom that deficiency of YIN body constitution can effectively alleviated or eliminate to the Chinese medicine preparation of deficiency of body fluid symptom, mainly be presented as sensation health, heating on the face, anti-summer-heat, xerosis cutis that can't stand summer; Often feel the heating of the trick heart, buccal flushing or red partially; Often feel that eyes are dry and astringent, often dry mouth and throat, insomnia easily; Ill symptomses such as frequent constipation with dry stool provide the treatment experimental data of several kinds of classical symptoms to explain below:
(1), feels health, heating on the face, anti-summer-heat that can't stand summer.
1, experimental technique:
1.1 experimental group is taken capsule provided by the invention, 2 times on the one, one time 3, routing motion therapy and dietetic therapy; Matched group is taken treatment deficiency of YIN medicine routing motion therapy and dietetic therapy.Two groups equal 30 days be 1 course of treatment, finish back evaluation curative effect the course of treatment.
1.2 comparability inspection before the treatment.
1.2.1 as shown in table 1, sex difference does not have significance before experimental group and the treatment of control group.
Sex ratio before the table 1 liang group treatment.
Figure BSA00000478033700091
Figure BSA00000478033700101
More than each the group through X 2Check (chi-square test), difference that there are no significant.
1.2.2 as shown in table 2, the age distributional difference does not have significance before experimental group and the treatment of control group.
Age distribution before the table 2 liang group treatment
Figure BSA00000478033700102
More than each the group through X 2Check, difference that there are no significant.
1.2.3 the sick there was no significant difference of planting before experimental group and the treatment of control group.
2, criterion of therapeutical effect and assessment method:
Mark according to items such as symptom, sign, meridians detection inspections.Produce effects: fundamental symptoms disappears, and meridians detect the inspection kidney channel, the Liver Channel index is shown in green, are tending towards normal; Effectively: fundamental symptoms obviously improves, and meridians detect the inspection kidney channel, the Liver Channel index is shown as indigo plant, yellow; Invalid: fundamental symptoms does not change, and meridians detect the inspection kidney channel, the Liver Channel index is shown in red.
3, therapeutic outcome.
3.1 total effects is relatively seen table 4 between group, the Ridit assay shows that total effects has significant difference between matched group and treatment group, and the experimental group total effective rate is 79.2%, obviously is superior to matched group 44.0%, and prompting experimental group curative effect is better.
Total effects relatively between table 4 group
Figure BSA00000478033700103
(2), xerosis cutis, often feel trick heart heating.
1, experimental technique:
1.1 experimental group is taken capsule provided by the invention, 2 times on the one, one time 3, routing motion therapy and dietetic therapy; Matched group is normally taken treatment hyperactivity of fire caused by deficiency of YIN medicine.Two groups equal 15 days be 1 course of treatment, finish back evaluation curative effect the course of treatment.
1.2 comparability inspection before the treatment.
1.2.1 as shown in table 5, sex difference does not have significance before experimental group and the treatment of control group.
Sex ratio before the table 5 liang group treatment.
Figure BSA00000478033700111
More than each the group through X 2Check, difference that there are no significant.
1.2.2 as shown in table 6, the age distributional difference does not have significance before experimental group and the treatment of control group.
Age distribution before the table 6 liang group treatment
Figure BSA00000478033700112
More than each the group through X 2Check, difference that there are no significant.
1.2.3 the sick there was no significant difference of planting before experimental group and the treatment of control group.
More than each the group through X 2Check, difference that there are no significant.
2, criterion of therapeutical effect and assessment method.
Mark according to items such as symptom, sign, blood pressure tests.Produce effects: cardinal symptom is most of to disappear, and kidney channel, Liver Channel index recover normal basically; Effectively: cardinal symptom is most of to disappear, and kidney channel, Liver Channel index make moderate progress; Invalid: as not meet above standard person.
3, therapeutic outcome.
3.1 total effects is relatively seen table 8 between group, the Ridit assay shows that total effects has significant difference between matched group and treatment group, and treatment group total effective rate is 85.7%, matched group 53.0%, and prompting experimental group curative effect is better.
Total effects relatively between table 8 group
Figure BSA00000478033700121
Treatment group therapeutic efficiency is higher, and prompting treatment group curative effect is better.In addition, do not see that obvious adverse reaction takes place, explain that these article are without any side effects, safe and reliable.
(3), other symptoms.
1. clinical manifestation: buccal flushing or red partially, often feel that eyes are dry and astringent, often dry mouth and throat is had a sleepless night easily, often constipation with dry stool.
2. experimental technique.
2.1 experimental group is taken capsule provided by the invention, 2 times on the one, one time 2, routing motion therapy and dietetic therapy; Matched group is not taken any medicine, is not carried out any motion.Two groups equal 7 days be 1 course of treatment, finish back evaluation curative effect the course of treatment.
2.2 comparability inspection before the treatment.
2.2.1 as shown in table 9, sex difference does not have significance before experimental group and the treatment of control group.
Sex ratio before the table 9 liang group treatment
Figure BSA00000478033700131
More than each the group through X 2Check, difference that there are no significant.
2.2.2 as shown in table 10, the age distributional difference does not have significance before experimental group and the treatment of control group.
Age distribution before the table 10 liang group treatment
Figure BSA00000478033700132
More than each the group through X 2Check, difference that there are no significant.
2.2.3 as shown in table 11, the sick there was no significant difference of planting before experimental group and the treatment of control group.
Symptom gathers before the table 11 liang group treatment
Figure BSA00000478033700133
More than each the group through X 2Check, difference that there are no significant.
3, criterion of therapeutical effect and assessment method.
Mark according to items such as symptom, signs.Produce effects: take 3 courses of treatment of capsule provided by the invention, and through observing 10 days, symptom is improved obviously or eliminated; Effectively: 3 courses of treatment of capsule provided by the invention, and improvement is arranged through observing 10 days symptoms; Invalid: as not meet above standard person.
4, therapeutic outcome.
4.1 total effects is relatively seen table 12 between group, the Ridit assay shows that total effects has significant difference between matched group and treatment group, and treatment group total effective rate is 89.8%, obviously is superior to matched group 53.9%, and prompting experimental group curative effect is better.
Total effects relatively between table 12 group
Figure BSA00000478033700141
The analysis of comparable result shows between this group data set, physical data between each group, and no significant differences such as sex, age, the course of disease and the distribution of sick kind, comparability is better between the prompting group, and two groups have harmony.
Treatment group therapeutic efficiency is higher, and prompting treatment group curative effect is better.In addition, do not see that obvious adverse reaction takes place, explain that these article are without any side effects, safe and reliable.
The present invention is not limited to above-mentioned preferred forms, and anyone should learn the structural change of under enlightenment of the present invention, making, and every have identical or close technical scheme with the present invention, all falls within protection scope of the present invention.

Claims (6)

1. be used for deficiency of YIN body constitution people and alleviate the Chinese medicine preparation of deficiency of body fluid symptom; It is characterized in that the active ingredient of this Chinese medicine preparation is processed by the crude drug of following mass fraction: Rhizoma Polygonati Odorati 40-70, Semen Pruni 80-110, Bulbus Lilii 60-150, Radix Glycyrrhizae 60-190, Rhizoma Polygonati 20-60, Rhizoma Dioscoreae 90-160, Fructus Lycii 80-170, Semen Cassiae 20-60, Fructus Mori 30-70, Folium Mori 40-60, Flos Chrysanthemi 30-60, Semen Persicae 50-80, Semen Sesami Nigrum 40-70, Fructus Citri Sarcodactylis 30-70, Radix Platycodonis 40-80.
2. as claimed in claim 1ly be used for the Chinese medicine preparation that deficiency of YIN body constitution people is alleviated the deficiency of body fluid symptom; It is characterized in that the active ingredient of this Chinese medicine preparation is processed by the crude drug of following mass fraction: Rhizoma Polygonati Odorati 50-60, Semen Pruni 90-100, Bulbus Lilii 80-120, Radix Glycyrrhizae 70-110, Rhizoma Polygonati 40-50, Rhizoma Dioscoreae 100-150, Fructus Lycii 90-150, Semen Cassiae 30-50, Fructus Mori 40-60, Folium Mori 45-55, Flos Chrysanthemi 40-50, Semen Persicae 60-70, Semen Sesami Nigrum 50-60, Fructus Citri Sarcodactylis 40-60, Radix Platycodonis 50-70.
3. as claimed in claim 1ly be used for the Chinese medicine preparation that deficiency of YIN body constitution people is alleviated the deficiency of body fluid symptom; It is characterized in that the active ingredient of this Chinese medicine preparation is processed by the crude drug of following mass fraction: Rhizoma Polygonati Odorati 55, Semen Pruni 95, Bulbus Lilii 100, Radix Glycyrrhizae 110, Rhizoma Polygonati 45, Rhizoma Dioscoreae 130, Fructus Lycii 120, Semen Cassiae 40, Fructus Mori 50, Folium Mori 50, Flos Chrysanthemi 45, Semen Persicae 65, Semen Sesami Nigrum 55, Fructus Citri Sarcodactylis 50, Radix Platycodonis 60.
4. be used for the Chinese medicine preparation that deficiency of YIN body constitution people is alleviated the deficiency of body fluid symptom as claim 1 to 3 each claim is described, it is characterized in that this Chinese medicine preparation is granule, tablet, capsule, pill or syrup.
5. be used for deficiency of YIN body constitution people and alleviate the method for preparing of the Chinese medicine preparation of deficiency of body fluid symptom, it is characterized in that may further comprise the steps:
A10, get ten five tastes crude drug by following mass fraction; Rhizoma Polygonati Odorati 40-70, Semen Pruni 80-110, Bulbus Lilii 60-150, Radix Glycyrrhizae 60-190, Rhizoma Polygonati 20-60, Rhizoma Dioscoreae 90-160, Fructus Lycii 80-170, Semen Cassiae 20-60, Fructus Mori 30-70, Folium Mori 40-60, Flos Chrysanthemi 30-60, Semen Persicae 50-80, Semen Sesami Nigrum 40-70, Fructus Citri Sarcodactylis 30-70, Radix Platycodonis 40-80, the drinking water that adds 8 times of amounts of crude drug gross mass soaked 0.5-1.0 hour;
A20, decoction 1-1.5 hour are filtered and are obtained extracting solution for the first time;
The drinking water that A30, the raw material medicinal residues after will filtering add 8 times of amounts once more decocted 1-1.5 hour, filtered to obtain extracting solution for the second time;
A40, with said first time of extracting solution and after the said second time, extracting solution mixed, it is 1.25-1.3/70 ℃ clear paste that heating is concentrated into proportion;
A50, said clear paste vacuum drying is become dried cream;
A60, with broken mistake 80 mesh sieves of said dried cream powder, add corresponding auxiliary material and process corresponding Chinese medicine preparation.
6. the method for preparing of Chinese medicine preparation as claimed in claim 5 is characterized in that, said adjuvant is one or more in binding agent, filler, correctives, wetting agent, antiseptic, the antioxidant.
CN2011100999229A 2011-04-21 2011-04-21 Chinese medicinal preparation for relieving body fluid deficiency for people with yin-deficiency physique, preparation method thereof and application thereof Expired - Fee Related CN102178840B (en)

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