CN111298037A - Traditional Chinese medicine composition for conditioning and treating yin deficiency constitution and preparation and application thereof - Google Patents

Traditional Chinese medicine composition for conditioning and treating yin deficiency constitution and preparation and application thereof Download PDF

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CN111298037A
CN111298037A CN202010229894.7A CN202010229894A CN111298037A CN 111298037 A CN111298037 A CN 111298037A CN 202010229894 A CN202010229894 A CN 202010229894A CN 111298037 A CN111298037 A CN 111298037A
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chinese medicine
traditional chinese
medicine composition
conditioning
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程亚伟
屈凯
陈磊
程亚博
丁一
王忆勤
周灏
袁冬梅
黄家彦
王珊
颜芬
林夏
徐经世
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    • A61K36/185Magnoliopsida (dicotyledons)
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Abstract

The invention provides a traditional Chinese medicine composition for conditioning and treating yin deficiency constitution, and a preparation and application thereof, wherein the active components of the traditional Chinese medicine composition comprise the following raw material medicines in parts by weight: 50-150 parts of radix rehmanniae, 80-130 parts of yam, 80-120 parts of dogwood, 50-150 parts of rhizoma alismatis, 80-120 parts of poria cocos, 50-150 parts of salvia miltiorrhiza, 80-120 parts of polygonatum, 80-120 parts of lily, 70-130 parts of tremella, 80-120 parts of citron, 80-120 parts of mulberry, 250 parts of fructus aurantii 160, 80-120 parts of platycodon grandiflorum and 60-130 parts of black sesame, 80-130 parts of medlar, 50-150 parts of dendrobium, 80-120 parts of prepared rhizome of rehmannia, 80-120 parts of angelica, 50-150 parts of white peony root, 40-70 parts of ligusticum wallichii, 70-130 parts of chrysanthemum, 80-120 parts of mulberry leaf, 80-120 parts of rice sprout, 80-120 parts of lotus seed, 80-120 parts of glossy privet fruit, 80-120 parts of eclipta alba, 80-120 parts of flos mume and 80-120 parts of poria with hostwood. The medicines have the effect of nourishing yin and tonifying deficiency, and have obvious regulation and treatment effects on yin deficiency constitution.

Description

Traditional Chinese medicine composition for conditioning and treating yin deficiency constitution and preparation and application thereof
Technical Field
The invention relates to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for conditioning and treating yin deficiency constitution, and a preparation and application thereof.
Background
The traditional Chinese medicine Constitution (conformation of T CM) refers to the comprehensive and relatively stable inherent characteristics of morphological structure, physiological function and psychological state formed on the basis of innate endowments and acquired aftermath in the life process of human body. The research shows that the 9 constitution types and the formed conceptual system thereof reflect the individual characteristics of different people groups, the peaceful quality is normal constitution, and the qi deficiency quality, the yang deficiency quality, the yin deficiency quality, the phlegm dampness quality, the damp-heat quality, the blood stasis quality, the qi depression quality and the specific quality are 8 biased constitutions. The traditional Chinese medicine constitution research shows that the occurrence of certain diseases, even a class of diseases, is closely related to the constitution of human beings. The constitution of the human body is relatively stable and changeable, and the unbalanced state of the constitution of the human body can be improved and adjusted through intervention, so that the health is recovered, and even the treatment viewpoint is fundamentally changed.
Constitution with yin deficiency, (1) general characteristics: deficient heat, manifested as dry mouth and throat, feverish palms and soles, is mainly characterized by yin fluid deficiency. (2) The shape is characterized in that: the body shape is thin. (3) Common manifestations are: feverish palms and soles, dry mouth and throat, slightly dry nose, preference for cold drink, dry stool, red tongue with little saliva and thready and rapid pulse. (4) Psychological characteristics: the feeling of urgency, moving outward and lively. (5) The incidence tendency is as follows: susceptible to diseases such as consumptive disease, loss of essence, insomnia, etc.; the pathogenic factors are apt to transform into heat. (6) Adaptability to external environment: winter tolerance is not tolerant: intolerance to the pathogenic heat and dryness. But only by self-conditioning, the effect is not obvious, and the daily work efficiency and the life quality of the patient are affected for a long time. In order to radically improve the health of yin deficiency constitutions, the inventor develops a traditional Chinese medicine composition formula for effectively regulating and treating yin deficiency constitutions.
Disclosure of Invention
In view of the above, the invention provides a traditional Chinese medicine composition for conditioning and treating yin deficiency constitution, and a preparation and an application thereof.
The technical scheme of the invention is realized as follows: the active components of the traditional Chinese medicine composition for regulating and treating yin deficiency constitution comprise the following raw material medicines in parts by weight: 50-150 parts of radix rehmanniae, 80-130 parts of yam, 80-120 parts of dogwood, 50-150 parts of rhizoma alismatis, 80-120 parts of poria cocos, 50-150 parts of salvia miltiorrhiza, 80-120 parts of polygonatum, 80-120 parts of lily, 70-130 parts of tremella, 80-120 parts of citron, 80-120 parts of mulberry, 250 parts of fructus aurantii 160, 80-120 parts of platycodon grandiflorum and 60-130 parts of black sesame, 80-130 parts of medlar, 50-150 parts of dendrobium, 80-120 parts of prepared rhizome of rehmannia, 80-120 parts of angelica, 50-150 parts of white peony root, 40-70 parts of ligusticum wallichii, 70-130 parts of chrysanthemum, 80-120 parts of mulberry leaf, 80-120 parts of rice sprout, 80-120 parts of lotus seed, 80-120 parts of glossy privet fruit, 80-120 parts of eclipta alba, 80-120 parts of flos mume and 80-120 parts of poria with hostwood.
Preferably, the active components of the traditional Chinese medicine composition comprise the following raw material medicines in parts by weight: 95-105 parts of radix rehmanniae, 95-105 parts of Chinese yam, 95-105 parts of dogwood, 95-105 parts of rhizoma alismatis, 95-105 parts of poria cocos, 95-105 parts of salvia miltiorrhiza, 95-105 parts of polygonatum, 95-105 parts of lily, 95-105 parts of tremella, 95-105 parts of citron, 95-105 parts of mulberry, 190 parts of fructus aurantii, 95-105 parts of platycodon grandiflorum and 95-105 parts of black sesame, 95-105 parts of medlar, 95-105 parts of dendrobium, 95-105 parts of prepared rehmannia root, 95-105 parts of angelica, 95-105 parts of white peony root, 58-62 parts of ligusticum wallichii, 95-105 parts of chrysanthemum, 95-105 parts of mulberry leaf, 95-105 parts of rice sprout, 95-105 parts of lotus seed, 95-105 parts of glossy privet fruit, 95-105 parts of eclipta alba, 95-105 parts of flos mume and 95-105 parts of poria with hostwood.
Preferably, the active components of the traditional Chinese medicine composition comprise the following raw material medicines in parts by weight: 100 parts of radix rehmanniae, 100 parts of Chinese yam, 100 parts of dogwood, 100 parts of rhizoma alismatis, 100 parts of poria cocos, 100 parts of salvia miltiorrhiza, 100 parts of polygonatum, 100 parts of lily, 100 parts of tremella, 100 parts of citron, 100 parts of mulberry, 200 parts of fructus aurantii, 100 parts of platycodon grandiflorum, 100 parts of black sesame, 100 parts of wolfberry, 100 parts of dendrobe, 100 parts of prepared rehmannia root, 100 parts of angelica, 100 parts of white paeony root, 60 parts of ligusticum wallichii, 100 parts of chrysanthemum, 100 parts of mulberry leaf, 100 parts of rice sprout, 100 parts of lotus seed, 100 parts of glossy privet fruit, 100 parts of eclipta alba, 100 parts of cupula and.
Preferably, the dogwood is wine dogwood, and the Chinese yam is common yam rhizome.
A traditional Chinese medicine composition preparation for conditioning yin-deficiency constitution comprises the traditional Chinese medicine composition for conditioning yin-deficiency constitution, wherein the traditional Chinese medicine composition preparation is one of a paste formula, a tea drink, a pill, a pellet, a decoction, a granule, a capsule and an oral liquid.
The traditional Chinese medicine composition paste formula for conditioning yin-deficiency constitution comprises any one of the traditional Chinese medicine compositions for conditioning yin-deficiency constitution, and further comprises the following raw materials in parts by weight: 50-150 parts of American ginseng, 70-230 parts of turtle shell glue, 70-230 parts of tortoise-plastron glue and 450 parts of maltose.
The invention relates to application of a traditional Chinese medicine composition for conditioning yin-deficiency constitution in preparation of a medicine for conditioning yin-deficiency constitution.
Compared with the prior art, the invention has the beneficial effects that: in the formula of the invention, dendrobium, lily, tremella and polygonatum odoratum are used as monarch drugs for nourishing yin and promoting the production of body fluid, and rehmannia root, glossy privet fruit and eclipta alba are used for nourishing yin and cooling blood; radix rehmanniae Preparata, rhizoma Dioscoreae, Corni fructus, Mori fructus, semen Sesami Niger, fructus Lycii for invigorating kidney and replenishing essence, radix Angelicae sinensis, radix Paeoniae alba, rhizoma Ligustici Chuanxiong, Saviae Miltiorrhizae radix for nourishing blood and yin, fructus Citri, fructus Aurantii, radix Platycodi, and flos Pruni mume for regulating qi activity, and are used as ministerial drugs; poria and semen Nelumbinis have effects of calming heart and tranquilizing mind, flos Chrysanthemi and folium Mori have effects of clearing heat and calming liver, Poria and Alismatis rhizoma have effects of clearing heat and promoting diuresis and preventing dampness, and fructus oryzae has effects of regulating stomach function and promoting transportation and transformation, and are used as adjuvant drugs together. The medicines have the effects of nourishing yin and tonifying deficiency, have obvious regulation and treatment effects on yin deficiency constitution, and can recover and keep relatively healthy and mild for a long time. In addition, the American ginseng, the turtle shell glue, the tortoise-plastron glue and the maltose are matched to prepare the paste formula, wherein the American ginseng is the monarch drug, the turtle shell glue, the tortoise-plastron glue and the maltose are used for nourishing blood, nourishing yin and collecting paste, and are used as adjuvant drugs together to prepare the paste formula, so that the paste formula is convenient for patients to carry, is palatable, effectively improves the enthusiasm of taking, and enables the curative effect to be better and fully exerted.
Detailed Description
In order to better understand the technical content of the invention, specific examples are provided below to further illustrate the invention.
The experimental methods used in the examples of the present invention are all conventional methods unless otherwise specified.
The materials, reagents and the like used in the examples of the present invention can be obtained commercially without specific description.
The basic conditions of the main raw material drugs are described in the Chinese pharmacopoeia, the Chinese dictionary and the Chinese herbal medicine.
Radix rehmanniae: [ PROPERTIES AND FLAVOUR ] sweet and cold. [ GUIJING ] GUIJING is responsible for the heart, liver and kidney meridians. [ FUNCTIONS ] SHENGQING: clear heat and cool blood, nourish yin, promote the production of body fluid. Can be used for treating fever with deep-red tongue, polydipsia, yin deficiency, internal heat, bone steaming, internal heat, diabetes, hematemesis, epistaxis, macula, and eruption.
Chinese yam: [ PROPERTIES AND FLAVOUR ] sweet and neutral. [ GUIJING ] can enter spleen, lung and kidney meridians. [ FUNCTIONS ] can tonify spleen and stomach, promote the production of body fluid and nourish lung, tonify kidney and arrest seminal emission. Can be used for treating spleen deficiency, anorexia, chronic diarrhea, lung deficiency, cough, asthma, spermatorrhea, leukorrhagia, frequent micturition, and diabetes due to deficiency heat.
Dogwood fruit: [ PROPERTIES AND WESTERN PROPERTIES ] is sour, astringent and slightly warm. [ GUIJING ] enters liver and kidney meridians. [ FUNCTIONS ] can tonify liver and kidney, astringe essence and relieve depletion. Can be used for treating vertigo, tinnitus, soreness of waist and knees, sexual impotence, spermatorrhea, enuresis, frequent micturition, metrorrhagia, leukorrhagia, sweating, asthenia, internal heat, and diabetes.
Rhizoma alismatis: [ PROPERTIES AND FLAVOUR ] sweet and cold. [ GUIJING ] enters kidney and bladder meridians. [ FUNCTIONS ] can promote urination and clear away damp-heat. Can be used for treating dysuria, edema, abdominal distention, diarrhea, oliguria, phlegm retention, vertigo, and pain due to stranguria and heat; hyperlipidemia.
Tuckahoe, poria cocos: [ PROPERTIES AND FLAVOUR ] sweet, bland and mild. [ GUIJING ] can enter heart, lung, spleen and kidney meridians. [ FUNCTIONS ] can induce diuresis, remove dampness, invigorate spleen, and tranquilize mind. Can be used for treating edema, oliguria, phlegm and fluid retention, dizziness, palpitation, spleen deficiency, anorexia, loose stool, diarrhea, uneasiness, palpitation, and insomnia.
Red sage root: [ PROPERTIES AND FLAVOUR ] bitter and slightly cold. [ GUIJING ] returning to the heart and liver meridians. [ FUNCTIONS ] can dispel blood stasis, relieve pain, promote blood circulation, dredge channels, clear away heart-fire and relieve restlessness. Can be used for treating menoxenia, amenorrhea, dysmenorrhea, abdominal mass, thoracico-abdominal pain, arthralgia due to heat, pyocutaneous disease, swelling and pain, vexation, and insomnia; hepatosplenomegaly, angina pectoris.
Fragrant solomonseal rhizome: [ PROPERTIES AND FLAVOUR ] sweet and slightly cold. [ GUIJING ] enters lung and stomach meridians. [ FUNCTIONS ] can nourish yin, moisten dryness, promote the production of body fluid and quench thirst. Can be used for treating yin injury of lung and stomach, cough due to dryness-heat, dry throat, thirst, and diabetes due to internal heat.
Lily: [ PROPERTIES AND FLAVOUR ] sweet and cold. [ GUIJING ] GUIJING is responsible for heart and lung meridians. [ FUNCTIONS ] can nourish yin, moisten lung, clear heart fire and induce tranquilization. Can be used for treating chronic cough due to yin deficiency, blood-stained sputum, vexation, palpitation, insomnia, dreaminess, and absentmindedness.
White fungus: [ PROPERTIES AND FLAVOUR ] sweet and neutral. [ GUIJING ] entering meridians and lung; the stomach; the kidney channel. [ FUNCTIONS ] can tonify lung, replenish qi, nourish yin, and moisten dryness. Can be used for treating asthenia after illness, lung deficiency, chronic cough, blood-stained sputum, metrorrhagia, constipation, hypertension, and angiosclerosis.
Citron: [ PROPERTIES AND WESTERN ] is pungent, bitter, sour and warm in flavor. [ GUIJING ] enters liver, spleen and lung meridians. [ FUNCTIONS ] can soothe the liver, regulate qi, relieve epigastric distention, and resolve phlegm. Can be used for treating qi stagnation of liver and stomach, distending pain in chest and hypochondrium, fullness and distention in stomach and abdomen, emesis, belching, excessive phlegm and cough.
Mulberry: [ PROPERTIES AND FLAVOURS ]: sweet, sour and cold. [ meridian tropism ]: it enters heart, liver and kidney meridians. [ Functional indications ]: tonify blood, nourish yin, promote the production of body fluid and moisten dryness. Can be used for treating vertigo, tinnitus, palpitation, insomnia, premature gray hair, thirst due to body fluid consumption, internal heat, diabetes, and constipation due to blood deficiency.
Fructus aurantii: [ PROPERTIES AND WESTERN ] is bitter, pungent, sour and warm in taste. [ GUIJING ] can enter spleen and stomach meridians. [ FUNCTIONS ] can regulate qi, relieve epigastric distention, remove food stagnation and relieve distension. Can be used for treating qi stagnation in chest and hypochondrium, fullness and pain, dyspepsia, and retention of phlegm and fluid; gastroptosis, rectocele, uterine prolapse.
Balloon flower: [ PROPERTIES AND WESTERN ] is bitter, pungent and mild. [ GUIJING ] enters lung meridian. [ FUNCTIONS ] can ventilate lung, relieve sore throat, dispel phlegm, and expel pus. Can be used for treating cough with excessive phlegm, chest distress, pharyngalgia, hoarseness, lung carbuncle, suppuration, and pyocutaneous disease with pus formation.
Black sesame seed: [ PROPERTIES AND FLAVOUR ] sweet and neutral. [ GUIJING ] enters liver, kidney and large intestine meridians. [ FUNCTIONS ] can tonify liver and kidney, nourish essence and blood, moisten intestine and dry. Can be used for treating dizziness, dim eyesight, tinnitus, deafness, premature gray hair, alopecia after illness, and constipation due to intestinal dryness.
Wolfberry fruit: [ PROPERTIES AND FLAVOUR ] sweet and neutral. [ GUIJING ] enters liver and kidney meridians. [ FUNCTIONS ] can nourish liver and kidney, replenish vital essence and improve eyesight. Can be used for treating asthenia, soreness of waist and knees, vertigo, tinnitus, internal heat, diabetes, blood deficiency, sallow complexion, and blurred vision.
Dendrobe: [ PROPERTIES AND WESTERN PROPERTIES ] is sweet, bland, slightly salty and cold. [ GUIJING ] enters stomach, lung and kidney meridians. [ FUNCTIONS ] can promote the production of body fluid, nourish stomach, clear heat and nourish yin. It is indicated for dry mouth with polydipsia due to fluid damage by febrile disease, and deficiency heat after illness, yin damaging dark eyes.
Prepared rhizome of rehmannia: [ PROPERTIES AND FLAVOUR ] sweet and slightly warm. [ GUIJING ] enters liver and kidney meridians. [ FUNCTIONS ] can nourish yin, tonify blood, replenish vital essence and replenish marrow. Can be used for treating deficiency of liver-yin and kidney-yin, soreness of waist and knees, hectic fever, night sweat, nocturnal emission, internal heat, diabetes, blood deficiency, sallow complexion, cardiopalmus, severe palpitation, menoxenia, metrorrhagia, metrostaxis, hemorrhage, giddiness, tinnitus, and early white beard and hair.
Chinese angelica: [ PROPERTIES AND FLAVOUR ] sweet, pungent and warm. [ GUIJING ] enters liver, heart and spleen meridians. [ FUNCTIONS ] can tonify blood, promote blood circulation, regulate menstruation, relieve pain, moisten intestines and relieve constipation. Can be used for treating blood deficiency, sallow complexion, giddiness, palpitation, menoxenia, amenorrhea, dysmenorrhea, asthenia cold, abdominal pain, constipation due to intestinal dryness, rheumatic arthralgia, traumatic injury, superficial infection, pyocutaneous disease. The wine angelica sinensis can activate blood and promote menstruation. Can be used for treating amenorrhea, dysmenorrhea, rheumatalgia, and traumatic injury.
White peony root: [ PROPERTIES AND WESTERN PROPERTIES ] is bitter, sour and slightly cold. [ GUIJING ] enters liver and spleen meridians. [ FUNCTIONS ] can calm the liver, alleviate pain, nourish blood, regulate menstruation, astringe yin and stop sweating. Can be used for treating headache, vertigo, hypochondriac pain, abdominal pain, limb spasm and pain, blood deficiency, sallow complexion, menoxenia, spontaneous perspiration, and night sweat.
Ligusticum wallichii: [ PROPERTIES AND FLAVOUR ] pungent and warm. [ GUIJING ] enters liver, gallbladder and pericardium. [ FUNCTIONS ] can promote blood circulation, promote the circulation of qi, dispel wind, and relieve pain. Can be used for treating menoxenia, amenorrhea, dysmenorrhea, abdominal pain, pricking pain in chest and hypochondrium, traumatic injury, swelling and pain, headache, and rheumatalgia.
Chrysanthemum: [ PROPERTIES AND WESTERN PROPERTIES ] is sweet, bitter and slightly cold. [ GUIJING ] enters lung and liver meridians. [ FUNCTIONS ] can dispel pathogenic wind, clear away heat, calm the liver, and improve eyesight. Can be used for treating wind-heat type common cold, headache, giddiness, conjunctival congestion, swelling and pain, and blurred vision.
Mulberry leaf: [ PROPERTIES AND FLAVOURS ] sweet, bitter and cold. [ GUIJING ] enters lung and liver meridians. [ FUNCTIONS ] can dispel wind-heat, clear lung-heat, moisten dryness, clear liver-heat and improve eyesight. Can be used for treating wind-heat type common cold, lung heat type cough, dizziness, headache, conjunctival congestion, and dim eyesight.
Rice sprout: [ PROPERTIES AND FLAVOUR ] sweet and warm. [ GUIJING ] can enter spleen and stomach meridians. [ FUNCTIONS ] can promote digestion, regulate the middle warmer, invigorate the spleen and promote appetite. Can be used for treating dyspepsia, abdominal distention, halitosis, weakness of spleen and stomach, and anorexia. Is good at promoting digestion and not hungry and poor appetite.
Lotus seed: [ PROPERTIES AND FLAVOUR ] sweet, astringent and neutral. [ GUIJING ] can enter spleen, kidney and heart meridians. [ FUNCTIONS ] can tonify spleen, check diarrhea, tonify kidney, astringe essence, nourish heart, and induce tranquilization. Can be used for treating spleen deficiency, chronic diarrhea, spermatorrhea, leukorrhagia, palpitation, and insomnia.
Glossy privet fruit: [ PROPERTIES AND FLAVOUR ] sweet, bitter and neutral. [ GUIJING ] enters liver and kidney meridians. [ FUNCTIONS ] can nourish liver and kidney, improve eyesight and blacken hair. Can be used for treating vertigo, tinnitus, soreness of waist and knees, premature gray hair, and dim eyesight.
Eclipta alba: [ PROPERTIES AND FLAVOURS ] sweet, sour and cold. [ GUIJING ] enters kidney and liver meridians. [ FUNCTIONS ] can nourish liver and kidney, cool blood and stop bleeding. Can be used for treating odontoseisis, premature gray hair, vertigo, tinnitus, soreness of waist and knees, yin deficiency, blood heat, hematemesis, epistaxis, hematuria, dysentery with bloody stool, metrorrhagia, hemorrhage due to trauma, etc.
And (3) green calyx plum: [ PROPERTIES AND FLAVOUR ] bitter, slightly sweet and mild. [ FUNCTIONS ] can soothe the liver, relieve depression, stimulate the appetite and promote the secretion of saliva. Can be used for treating chest distress, anorexia, and globus hystericus.
Poria with hostwood: [ PROPERTIES AND FLAVOUR ] sweet and mild. [ FUNCTIONS ] can calm heart and induce tranquilization. It is suitable for palpitation, insomnia and amnesia.
American ginseng: [ PROPERTIES AND FLAVOUR ] sweet, slightly bitter and cool. [ GUIJING ] can enter heart, lung and kidney meridians. [ FUNCTIONS ] can invigorate qi, nourish yin, clear away heat, and promote the production of body fluid. Can be used for treating deficiency of qi and yin, internal heat, cough, asthma, phlegm blood, asthenia, fever, vexation, fatigue, diabetes, xerostomia, and dry throat.
Turtle shell glue: [ PROPERTIES AND FLAVOUR ] salty in taste; slightly cold in nature. [ GUIJING ] FEN (Lung-meridian tropism) lung; liver; the kidney channel. [ FUNCTIONAL INDICATIONS ] A medicine for nourishing yin and relieving fever; soften hardness and dissipate nodulation. Tidal fever due to yin deficiency; consumptive disease hemoptysis; chronic malaria; anzhi; swelling and pain of hemorrhoids; amenorrhea due to blood deficiency.
Tortoise-plastron glue: [ PROPERTIES AND FLAVOUR ] sweet, salty and neutral. [ GUIJING ] enters lung, liver and kidney meridians. [ FUNCTIONS ] can nourish yin, tonify blood, and stop bleeding. It is indicated for yin deficiency and blood deficiency, fatigue heat, steaming bone, hematemesis, epistaxis, dysphoria, palpitation, lumbago due to kidney deficiency, atrophy and weakness of feet and knees, metrorrhagia and metrostaxis, leukorrhagia.
The active components of the traditional Chinese medicine composition for regulating and treating yin deficiency constitution comprise the following raw material medicines in parts by weight: 50-150 parts of radix rehmanniae, 80-130 parts of yam, 80-120 parts of dogwood, 50-150 parts of rhizoma alismatis, 80-120 parts of poria cocos, 50-150 parts of salvia miltiorrhiza, 80-120 parts of polygonatum, 80-120 parts of lily, 70-130 parts of tremella, 80-120 parts of citron, 80-120 parts of mulberry, 250 parts of fructus aurantii 160, 80-120 parts of platycodon grandiflorum and 60-130 parts of black sesame, 80-130 parts of medlar, 50-150 parts of dendrobium, 80-120 parts of prepared rhizome of rehmannia, 80-120 parts of angelica, 50-150 parts of white peony root, 40-70 parts of ligusticum wallichii, 70-130 parts of chrysanthemum, 80-120 parts of mulberry leaf, 80-120 parts of rice sprout, 80-120 parts of lotus seed, 80-120 parts of glossy privet fruit, 80-120 parts of eclipta alba, 80-120 parts of flos mume and 80-120 parts of poria with hostwood.
Furthermore, Corni fructus is preferably Corni fructus processed with wine, and rhizoma Dioscoreae is preferably rhizoma Dioscoreae.
Furthermore, the raw materials are matched with 80-120 parts of American ginseng, 170 parts of turtle shell glue 130-.
Example 1
The active components of the traditional Chinese medicine composition for regulating and treating yin deficiency constitution comprise the following raw material medicines in parts by weight: 50 parts of radix rehmanniae, 80 parts of common yam rhizome, 80 parts of dogwood fruit wine, 50 parts of rhizoma alismatis, 80 parts of poria cocos, 50 parts of salvia miltiorrhiza, 80 parts of polygonatum, 120 parts of lily, 70 parts of tremella, 120 parts of citron, 80 parts of mulberry, 160 parts of fructus aurantii, 80 parts of platycodon grandiflorum, 60 parts of black sesame, 80 parts of wolfberry, 50 parts of dendrobium, 80 parts of prepared rehmannia root, 80 parts of angelica, 50 parts of white paeony root, 40 parts of ligusticum wallichii, 70 parts of chrysanthemum, 80 parts of mulberry leaf, 120 parts of rice sprout, 80 parts of lotus seed, 120 parts of glossy privet fruit, 80 parts of eclipta alba, 80 parts of cupula rolfs. 80 parts of American ginseng, 170 parts of turtle shell glue, 130 parts of tortoise-plastron glue and 250 parts of maltose are matched to prepare the paste formula according to a conventional method.
Example 2
The active components of the traditional Chinese medicine composition for regulating and treating yin deficiency constitution comprise the following raw material medicines in parts by weight: 150 parts of radix rehmanniae, 130 parts of common yam rhizome, 120 parts of dogwood fruit wine, 150 parts of rhizoma alismatis, 120 parts of poria cocos, 150 parts of salvia miltiorrhiza, 120 parts of polygonatum odoratum, 80 parts of lily, 130 parts of tremella, 80 parts of citron, 120 parts of mulberry, 250 parts of fructus aurantii, 120 parts of platycodon grandiflorum, 130 parts of black sesame, 130 parts of wolfberry fruit, 150 parts of dendrobium, 120 parts of prepared rehmannia root, 120 parts of angelica, 150 parts of white paeony root, 70 parts of ligusticum wallichii, 130 parts of chrysanthemum, 120 parts of mulberry leaf, 80 parts of rice sprout, 120 parts of lotus seed, 80 parts of glossy privet fruit, 120 parts of eclipta alba, 120 parts of cup. Mixing with 120 parts of American ginseng, 130 parts of turtle shell glue, 170 parts of tortoise-plastron glue and 350 parts of maltose, and preparing into a paste formula according to a conventional method.
Example 3
The active components of the traditional Chinese medicine composition for regulating and treating yin deficiency constitution comprise the following raw material medicines in parts by weight: 100 parts of radix rehmanniae, 100 parts of common yam rhizome, 100 parts of dogwood fruit wine, 100 parts of rhizoma alismatis, 100 parts of poria cocos, 100 parts of salvia miltiorrhiza, 100 parts of polygonatum, 100 parts of lily, 100 parts of tremella, 100 parts of citron, 100 parts of mulberry, 200 parts of fructus aurantii, 100 parts of platycodon grandiflorum, 100 parts of black sesame, 100 parts of wolfberry, 100 parts of dendrobium, 100 parts of prepared rehmannia root, 100 parts of angelica, 100 parts of white paeony root, 60 parts of ligusticum wallichii, 100 parts of chrysanthemum, 100 parts of mulberry leaf, 100 parts of rice sprout, 100 parts of lotus seed, 100 parts of glossy privet fruit, 100 parts of eclipta alba, 100 parts of cupula and 100. Matching 100 parts of American ginseng, 150 parts of turtle shell glue, 150 parts of tortoise-plastron glue and 300 parts of maltose, and preparing the paste formula according to a conventional method.
Example 4
The active components of the traditional Chinese medicine composition for regulating and treating yin deficiency constitution comprise the following raw material medicines in parts by weight: 100 parts of radix rehmanniae, 100 parts of common yam rhizome, 100 parts of dogwood fruit wine, 100 parts of rhizoma alismatis, 100 parts of poria cocos, 100 parts of salvia miltiorrhiza, 100 parts of polygonatum, 100 parts of lily, 100 parts of tremella, 100 parts of citron, 100 parts of mulberry, 200 parts of fructus aurantii, 100 parts of platycodon grandiflorum, 100 parts of black sesame, 100 parts of wolfberry fruit, 100 parts of dendrobium, 100 parts of prepared rehmannia root, 100 parts of angelica, 100 parts of white paeony root, 60 parts of ligusticum wallichii, 100 parts of chrysanthemum, 100 parts of mulberry leaf, 100 parts of rice sprout, 100 parts of lotus seed, 100 parts of glossy privet fruit, 100 parts of eclipta alba, 100 parts of cupula praeruptorum and 100 parts of poria with hos.
The Chinese medicinal composition of the invention is applied to clinic, and the treatment effect is as follows:
1. general data
210 patients with yin deficiency constitution are collected, and diagnosis and recording are carried out according to the Chinese medicine society Standard "classification and judgment of traditional Chinese medicine constitution" ZYXH/T157-one 2009. The observation groups were randomly divided into 1 group, 2 groups and 3 groups, and each group contained 70 cases.
Observing 1 group of 34 men and 36 women, with the mean age (52.3 ± 21.7) years;
observing 36 men and 34 women in 2 groups, with the mean age (52.8 ± 20.3) years;
the 3 groups were observed for 35 males and 35 females, with the mean age (52.1 ± 20.6) years.
2. The treatment method and the treatment course are as follows: observing that 1-3 groups of the Chinese medicinal composition formula in the embodiment 1-3 are respectively taken correspondingly, the Chinese medicinal composition formula is taken twice a day, one spoon (about 15g) of boiled water is taken each time, the Chinese medicinal composition formula is taken in the morning and evening, 3 months are taken as 1 treatment course, and the Chinese medicinal composition formula is taken for 2-4 treatment courses.
3. The clinical manifestations are as follows: is suitable for treating irritability, feverish palms and soles, dry throat and mouth, dry stool, dry eyes, red and slightly dry lips, dry skin, easy generation of wrinkles, vertigo, tinnitus, poor sleep, etc.
4. Criteria for judging therapeutic effects
4.1 method for determining body constitution type
All questions in the Chinese medicinal constitution Classification and judgment Table (see appendix of Chinese medicinal constitution Classification and judgment) were answered, each question was scored according to 5 grades, the original score and the conversion score were calculated, and the type of constitution was judged according to the standard.
Adding original score to each item score
Conversion fraction ═ [ (original number of fractions) (number of fractions × 4) ] × 100
4.2 peace and quality criteria
The mild and mild constitutions are normal constitutions, and the other 8 constitutions are abnormal constitutions. Criteria are given in the following table
Figure BDA0002428965920000091
4.3 therapeutic grading
And curing, namely basically eliminating the clinical symptoms of yin deficiency, judging that the result is yes according to the peaceful quality score, and recovering normal life.
Has the advantages that the clinical symptoms of yin deficiency are partially disappeared, all physical signs are gradually improved, and the judgment result of the grading of the peaceful quality is 'basic yes'.
No effect, no obvious improvement of symptom signs.
5. Therapeutic results
Figure BDA0002428965920000092
The clinical conditions show that the traditional Chinese medicine composition has an obvious effect on treating yin deficiency, the cure rate is more than 81.4%, and the total effective rate is more than 97.1%.
6. Typical cases
Medical record 1
For example, the female, age 42, is in the first diagnosis. Patient complaints are: insomnia is more than 5 years. The patient often needs to stay up to night for working reasons, the sleep is poor in the last 5 years, even the sleep is aggravated, and the patient takes the 'hypnotic medicine' for a long time to help sleep, so that the patient is in clinic at present. The symptoms are as follows: difficulty in falling asleep, dreaminess, easy awakening, emaciation, dry mouth, polydipsia, feverish sensation in chest, palms and soles, night sweat, yellowish urine, dry stools, scanty menstruation, red tongue with little coating, and thready and rapid pulse. And (3) Western diagnosis: insomnia. Traditional Chinese medicine constitution identification (Chinese medical society standard): constitutions with yin deficiency; traditional Chinese medicine disease diagnosis, insomnia; syndrome type refers to yin deficiency syndrome. The traditional Chinese medicine composition in the ointment formula of the embodiment 3 of the invention is taken twice a day for 4 months, and each time, one spoon (about 15g) of the traditional Chinese medicine composition is taken with boiled water, and the traditional Chinese medicine composition is taken in the morning and the evening.
In the second diagnosis, patients have better sleep after complaints of the ointment formula, and are easy to fall asleep earlier, and the patients do not need to take 'hypnotics' to help sleep, so that the patients have less dreams, are difficult to wake up, have better mouth dryness, have less sweating at night, relieve dysphoria with smothery sensation in the chest and normal stool. The tongue is pale red, the coating is thin and white, and the pulse is thready. The Chinese medicinal composition paste in the embodiment 3 of the invention is continuously taken for 3 months, and the administration method is the same as that of the traditional Chinese medicinal composition paste.
For the three diagnoses, patients have good sleep, no discomfort and enough menstruation, the weight is increased compared with the previous one, and the physique of the traditional Chinese medicine is identified as mild and mild. After 1 year, the test still shows that the body is healthy and mild.
Case 2
Guan somebody, male, 62 years old, first diagnosis. Patient complaints are: dry cough lasts for more than 10 years. The patient has the history of chronic bronchitis, cough easily appears in autumn and winter, and the chronic bronchitis treatment is ineffective for a long time. At present, the outpatient service of our hospital is seen. The symptoms are as follows: paroxysmal dry cough without phlegm easily occurs in autumn and winter, the cough is aggravated after eating spicy and pungent food, the smoke is dry and the mouth is drunk too much, the face is red and hot, the vexation and the insomnia are caused, the night sweat is caused, and the amnesia, the tinnitus, the yellow urine and the dry stool are caused sometimes. Red tongue with little coating and thready and rapid pulse. And (3) Western diagnosis: chronic bronchitis. Traditional Chinese medicine constitution identification (Chinese medical society standard): constitutions with yin deficiency; cough; syndrome type of yin deficiency of lung and kidney. The traditional Chinese medicine composition tea in the embodiment 4 of the invention is taken twice a day for 3 months, 15g of the tea is taken each time, and the tea is taken with boiled water in the morning and at night.
In the second diagnosis, patients complain of tea for drinking, the throat and mouth are dry, the restlessness and the insomnia are relieved, night sweat is improved, and obvious amnesia, tinnitus, yellow urine and constipation do not exist. The tongue is pale red, the coating is thin and white, and the pulse is thready. The traditional Chinese medicine composition tea drink of the embodiment 4 of the invention is continuously taken for 4 months, and the taking method is the same as before.
For the three diagnoses, patients who complain of tea drinking all the symptoms are removed, no discomfort is seen, and no cough appears after autumn comes, and the traditional Chinese medicine constitution is identified as mild. The patient is instructed to eat less spicy and pungent food. After 1 year, the test still shows that the body is healthy and mild.
7. Observation of adverse reactions
In the treatment and observation cases, patients with adverse reactions are not found, which shows that the traditional Chinese medicine composition is safe and reliable.
The traditional Chinese medicine composition can be prepared into pills, pellets, decoction, granules, capsules and oral liquid by a conventional method, and is applied to the regulation and treatment of yin deficiency constitution, namely the traditional Chinese medicine composition can be applied to the preparation of the medicine for regulating and treating the yin deficiency constitution.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like made within the spirit and principle of the present invention should be included in the scope of the present invention.

Claims (7)

1. The traditional Chinese medicine composition for conditioning and treating yin deficiency constitution is characterized in that active components of the composition comprise the following raw material medicines in parts by weight: 50-150 parts of radix rehmanniae, 80-130 parts of yam, 80-120 parts of dogwood, 50-150 parts of rhizoma alismatis, 80-120 parts of poria cocos, 50-150 parts of salvia miltiorrhiza, 80-120 parts of polygonatum, 80-120 parts of lily, 70-130 parts of tremella, 80-120 parts of citron, 80-120 parts of mulberry, 250 parts of fructus aurantii 160, 80-120 parts of platycodon grandiflorum and 60-130 parts of black sesame, 80-130 parts of medlar, 50-150 parts of dendrobium, 80-120 parts of prepared rhizome of rehmannia, 80-120 parts of angelica, 50-150 parts of white peony root, 40-70 parts of ligusticum wallichii, 70-130 parts of chrysanthemum, 80-120 parts of mulberry leaf, 80-120 parts of rice sprout, 80-120 parts of lotus seed, 80-120 parts of glossy privet fruit, 80-120 parts of eclipta alba, 80-120 parts of flos mume and 80-120 parts of poria with hostwood.
2. The traditional Chinese medicine composition for conditioning and treating constitution with yin deficiency as claimed in claim 1, wherein the active components comprise the following raw material medicines in parts by weight: 95-105 parts of radix rehmanniae, 95-105 parts of Chinese yam, 95-105 parts of dogwood, 95-105 parts of rhizoma alismatis, 95-105 parts of poria cocos, 95-105 parts of salvia miltiorrhiza, 95-105 parts of polygonatum, 95-105 parts of lily, 95-105 parts of tremella, 95-105 parts of citron, 95-105 parts of mulberry, 190 parts of fructus aurantii, 95-105 parts of platycodon grandiflorum and 95-105 parts of black sesame, 95-105 parts of medlar, 95-105 parts of dendrobium, 95-105 parts of prepared rehmannia root, 95-105 parts of angelica, 95-105 parts of white peony root, 58-62 parts of ligusticum wallichii, 95-105 parts of chrysanthemum, 95-105 parts of mulberry leaf, 95-105 parts of rice sprout, 95-105 parts of lotus seed, 95-105 parts of glossy privet fruit, 95-105 parts of eclipta alba, 95-105 parts of flos mume and 95-105 parts of poria with hostwood.
3. The traditional Chinese medicine composition for conditioning and treating constitution with yin deficiency as claimed in claim 2, wherein the active components comprise the following raw material medicines in parts by weight: 100 parts of radix rehmanniae, 100 parts of Chinese yam, 100 parts of dogwood, 100 parts of rhizoma alismatis, 100 parts of poria cocos, 100 parts of salvia miltiorrhiza, 100 parts of polygonatum, 100 parts of lily, 100 parts of tremella, 100 parts of citron, 100 parts of mulberry, 200 parts of fructus aurantii, 100 parts of platycodon grandiflorum, 100 parts of black sesame, 100 parts of wolfberry, 100 parts of dendrobe, 100 parts of prepared rehmannia root, 100 parts of angelica, 100 parts of white paeony root, 60 parts of ligusticum wallichii, 100 parts of chrysanthemum, 100 parts of mulberry leaf, 100 parts of rice sprout, 100 parts of lotus seed, 100 parts of glossy privet fruit, 100 parts of eclipta alba, 100 parts of cupula and.
4. The traditional Chinese medicine composition for conditioning constitution with yin deficiency as claimed in claim 1, wherein the Corni fructus is Corni fructus processed with wine, and the rhizoma Dioscoreae is rhizoma Dioscoreae.
5. A traditional Chinese medicine composition preparation for conditioning constitution with yin deficiency, which is characterized by comprising the traditional Chinese medicine composition for conditioning constitution with yin deficiency as claimed in any one of claims 1-4, wherein the traditional Chinese medicine composition preparation is one of a paste formulation, a tea drink, a pill, a pellet, a decoction, a granule, a capsule and an oral liquid.
6. The traditional Chinese medicine composition paste for conditioning yin-deficiency constitution is characterized by comprising the traditional Chinese medicine composition for conditioning yin-deficiency constitution according to any one of claims 1-4, wherein the traditional Chinese medicine composition further comprises the following raw materials in parts by weight: 50-150 parts of American ginseng, 70-230 parts of turtle shell glue, 70-230 parts of tortoise-plastron glue and 450 parts of maltose.
7. The use of the traditional Chinese medicine composition for conditioning yin-deficiency constitution according to any one of claims 1 to 6 in the preparation of a medicament for conditioning yin-deficiency constitution.
CN202010229894.7A 2020-03-27 2020-03-27 Traditional Chinese medicine composition for conditioning and treating yin deficiency constitution and preparation and application thereof Pending CN111298037A (en)

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