CN111388625A - Traditional Chinese medicine composition for regulating and treating blood stasis constitution and preparation and application thereof - Google Patents

Traditional Chinese medicine composition for regulating and treating blood stasis constitution and preparation and application thereof Download PDF

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CN111388625A
CN111388625A CN202010229897.0A CN202010229897A CN111388625A CN 111388625 A CN111388625 A CN 111388625A CN 202010229897 A CN202010229897 A CN 202010229897A CN 111388625 A CN111388625 A CN 111388625A
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blood stasis
chinese medicine
traditional chinese
medicine composition
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程亚伟
李景君
程亚博
陈磊
丁一
王忆勤
周灏
黄家彦
袁冬梅
王珊
颜芬
王婷
徐经世
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    • A61K36/185Magnoliopsida (dicotyledons)
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Abstract

The invention provides a traditional Chinese medicine composition for regulating and treating blood stasis constitution, and a preparation and application thereof, wherein the active components of the traditional Chinese medicine composition comprise the following raw material medicines in parts by weight: 50-150 parts of radix rehmanniae, 50-150 parts of peach kernel, 80-130 parts of hawthorn, 80-120 parts of phaseolus calcaratus, 70-120 parts of rose, 80-130 parts of Chinese rose, 70-120 parts of dried orange peel, 80-120 parts of poria cocos, 80-120 parts of medlar, 300 parts of astragalus membranaceus, 50-70 parts of cassia twig, 80-120 parts of ligusticum wallichii, 80-130 parts of moutan bark, 70-230 parts of angelica, 180 parts of fructus aurantii 130, 80-120 parts of platycodon grandiflorum, 80-120 parts of radix curcumae, 50-150 parts of radix paeoniae alba, 80-130 parts of red paeony root, 80-120 parts of allium macrostemon, 80-120 parts of citron, 70-120 parts of fingered citron, 80-120 parts of lotus seed, 70-230 parts of salvia miltiorrhiza, 250 parts of heterophylly 150, 80-120 parts of codonopsis pilosula, 80-130 parts of sea, 190 parts of pseudo-ginseng 130 and 80-120 parts of poria with hostwood. The medicines are combined to play the role of promoting blood circulation to remove blood stasis, have obvious regulation and treatment effects on the constitution with blood stasis, and recover and keep relatively healthy peaceful and mild for a long time.

Description

Traditional Chinese medicine composition for regulating and treating blood stasis constitution and preparation and application thereof
Technical Field
The invention relates to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for conditioning and treating blood stasis constitution, and a preparation and application thereof.
Background
The traditional Chinese medicine Constitution (conformation of T CM) refers to the comprehensive and relatively stable inherent characteristics of morphological structure, physiological function and psychological state formed on the basis of innate endowments and acquired aftermath in the life process of human body. The research shows that the 9 constitution types and the formed conceptual system thereof reflect the individual characteristics of different people groups, the peaceful quality is normal constitution, and the qi deficiency quality, the yang deficiency quality, the yin deficiency quality, the phlegm dampness quality, the damp-heat quality, the blood stasis quality, the qi depression quality and the specific quality are 8 biased constitutions. The traditional Chinese medicine constitution research shows that the occurrence of certain diseases, even a class of diseases, is closely related to the constitution of human beings. The constitution of the human body is relatively stable and changeable, and the unbalanced state of the constitution of the human body can be improved and adjusted through intervention, so that the health is recovered, and even the treatment viewpoint is fundamentally changed.
Blood stasis (type G), (1) general characteristics: unsmooth blood circulation is mainly characterized by blood stasis such as dark and dull complexion and purple tongue. (2) The shape is characterized in that: it is commonly seen in both obesity and emaciation. (3) Common manifestations are: dark complexion, pigmentation, easy appearance of ecchymosis, dark lip, dark tongue or petechia, dark or thickened sublingual collaterals, and unsmooth pulse. (4) Psychological characteristics: easy restlessness and amnesia. (5) The incidence tendency is as follows: it is prone to mass, pain and blood syndromes. (6) Adaptability to external environment: it is not tolerant to cold. The identification and adjustment method comprises the following steps: the skin is rough, the red hairs in the eyes are much, and the gum is easy to bleed. But only by self-conditioning, the effect is often not obvious, and the daily work efficiency and the life quality of the patient are influenced for a long time. In order to remarkably improve the health of the blood stasis constitution group, the inventor develops a traditional Chinese medicine composition formula for effectively regulating and treating the blood stasis constitution.
Disclosure of Invention
In view of the above, the invention provides a traditional Chinese medicine composition for conditioning and treating blood stasis constitutions, and a preparation and an application thereof.
The technical scheme of the invention is realized as follows: the active components of the traditional Chinese medicine composition for regulating and treating the blood stasis constitution comprise the following raw material medicines in parts by weight: 50-150 parts of radix rehmanniae, 50-150 parts of peach kernel, 80-130 parts of hawthorn, 80-120 parts of phaseolus calcaratus, 70-120 parts of rose, 80-130 parts of Chinese rose, 70-120 parts of dried orange peel, 80-120 parts of poria cocos, 80-120 parts of medlar, 300 parts of astragalus membranaceus, 50-70 parts of cassia twig, 80-120 parts of ligusticum wallichii, 80-130 parts of moutan bark, 70-230 parts of angelica, 180 parts of fructus aurantii 130, 80-120 parts of platycodon grandiflorum, 80-120 parts of radix curcumae, 50-150 parts of radix paeoniae alba, 80-130 parts of red paeony root, 80-120 parts of allium macrostemon, 80-120 parts of citron, 70-120 parts of fingered citron, 80-120 parts of lotus seed, 70-230 parts of salvia miltiorrhiza, 250 parts of heterophylly 150, 80-120 parts of codonopsis pilosula, 80-130 parts of sea, 190 parts of pseudo-ginseng 130 and 80-120 parts of poria with hostwood.
Preferably, the active components of the traditional Chinese medicine composition comprise the following raw material medicines in parts by weight: 95-105 parts of radix rehmanniae, 95-105 parts of peach kernel, 95-105 parts of raw hawthorn, 95-105 parts of phaseolus calcaratus, 95-105 parts of rose, 95-105 parts of Chinese rose, 95-105 parts of dried orange peel, 95-105 parts of poria cocos, 95-105 parts of wolfberry fruit, 190-containing crude astragalus root, 55-65 parts of cassia twig, 95-105 parts of ligusticum wallichii, 95-105 parts of moutan bark, 160 parts of angelica 140-containing materials, 160 parts of fructus aurantii 140-containing materials, 95-105 parts of platycodon grandiflorum, 95-105 parts of radix curcumae, 95-105 parts of white paeony root, 95-105 parts of red paeony root, 95-105 parts of allium macrostemon, 95-105 parts of citron, 95-105 parts of fingered citron, 95-105 parts of lotus seed, 160 parts of salvia miltiorrhiza 140-containing materials, 210 parts of radix pseudostellariae, 95-105 parts of codonopsis pilosula, 95, 140 portions of notoginseng and 160 portions of poria with hostwood 95-105 portions.
Preferably, the active components of the traditional Chinese medicine composition comprise the following raw material medicines in parts by weight: 100 parts of dried rehmannia root, 100 parts of peach kernel, 100 parts of hawthorn, 100 parts of red bean, 100 parts of rose, 100 parts of Chinese rose flower, 100 parts of dried orange peel, 100 parts of tuckahoe, 100 parts of medlar, 200 parts of astragalus root, 60 parts of cassia twig, 100 parts of szechuan lovage rhizome, 100 parts of tree peony bark, 150 parts of angelica, 150 parts of bitter orange, 100 parts of platycodon root, 100 parts of turmeric root-tuber, 100 parts of white paeony root, 100 parts of red paeony root, 100 parts of allium macrostemon, 100 parts of citron, 100 parts of fingered citron, 100 parts of lotus seed, 200 parts of astragalus root, 150 parts of salvia miltiorrhiza, 200 parts of radix pseudostellariae, 100 parts of codonopsis pilosula, 100 parts of.
Preferably, the hawthorn is raw hawthorn, and the astragalus is raw astragalus.
A traditional Chinese medicine composition preparation for regulating and treating blood stasis constitution comprises the traditional Chinese medicine composition for regulating and treating blood stasis constitution, wherein the traditional Chinese medicine composition preparation is one of a paste formula, a tea drink, a pill, a pellet, a decoction, a granule, a capsule and an oral liquid.
The traditional Chinese medicine composition paste for regulating and treating the blood stasis constitution comprises any one of the traditional Chinese medicine compositions for regulating and treating the blood stasis constitution, and further comprises the following raw materials in parts by weight: 50-150 parts of donkey-hide gelatin, 300 parts of yellow gelatin and 450 parts of maltose.
The invention discloses application of a traditional Chinese medicine composition for regulating and treating blood stasis constitutions in preparation of a medicine for regulating and treating blood stasis constitutions.
Compared with the prior art, the invention has the beneficial effects that: in the formula of the invention, peach kernel has the effects of breaking blood and removing blood stasis, ligusticum wallichii and radix curcumae have the effects of promoting qi and activating blood, moutan bark, red paeony root and salvia miltiorrhiza have the effects of cooling and activating blood, motherwort has the effects of promoting diuresis and activating blood, pseudo-ginseng and Chinese angelica have the effects of enriching and activating blood, and phaseolus calcaratus has the effects of removing blood stasis and expelling pus, and are mona; flos Rosae Rugosae, flos Rosae chinensis, fructus Citri and fructus Citri Sarcodactylis for dispersing stagnated liver qi and promoting qi circulation to assist blood circulation, radix Pseudostellariae, radix Codonopsis, radix astragali, Poria, qi invigorating and spleen invigorating, pericarpium Citri Tangerinae, fructus Aurantii, radix Platycodi and Bulbus Allii Macrostemi for regulating qi-flowing and promoting qi circulation, and are used as ministerial drugs; lotus seed, poria with hostwood, tranquilizing and allaying excitement, medlar, white peony root and dried rehmannia root, nourishing yin and blood, cassia twig, hawthorn and sea buckthorn, as well as spleen strengthening, digestion promoting and blood stasis removing, are used as adjuvants. The medicines have the effects of promoting blood circulation and removing blood stasis, and have obvious curative effect on conditioning and treating the constitution with blood stasis, and the health is recovered and kept peaceful and mild for a long time. In addition, donkey-hide gelatin, oxhide gelatin and maltose are matched to nourish yin and nourish blood to obtain the paste, and are used as adjuvants to prepare the paste formula, so that the paste formula is convenient for patients to carry, is palatable, effectively improves the enthusiasm of taking, and enables the curative effect to be better and fully exerted.
Detailed Description
In order to better understand the technical content of the invention, specific examples are provided below to further illustrate the invention.
The experimental methods used in the examples of the present invention are all conventional methods unless otherwise specified.
The materials, reagents and the like used in the examples of the present invention can be obtained commercially without specific description.
The basic conditions of the main raw material drugs are described in the Chinese pharmacopoeia, the Chinese dictionary and the Chinese herbal medicine.
Radix rehmanniae: [ PROPERTIES AND FLAVOUR ] sweet and cold. [ GUIJING ] GUIJING is responsible for the heart, liver and kidney meridians. [ FUNCTIONS ] SHENGQING: clear heat and cool blood, nourish yin, promote the production of body fluid. Can be used for treating fever with deep-red tongue, polydipsia, yin deficiency, internal heat, bone steaming, internal heat, diabetes, hematemesis, epistaxis, macula, and eruption.
Peach kernel: [ PROPERTIES AND FLAVOUR ] bitter, sweet and neutral. [ GUIJING ] GUIJING is responsible for the heart, liver and large intestine meridians. [ FUNCTIONS ] can promote blood circulation, dispel blood stasis, moisten intestines and relieve constipation. Can be used for treating amenorrhea, dysmenorrhea, abdominal mass, traumatic injury, intestinal dryness and constipation.
Hawthorn fruit: [ PROPERTIES AND FLAVOUR ] is sweet and sour, and slightly warm. [ GUIJING ] can enter spleen, stomach and liver meridians. [ FUNCTIONS ] can promote digestion, invigorate stomach, promote the circulation of qi, and remove blood stasis. Can be used for treating meat food stagnation, gastric cavity distention, dysentery abdominal pain, blood stasis amenorrhea, puerperal blood stasis, heart and abdomen stabbing pain, and hernia pain; hyperlipidemia.
Small red beans: [ PROPERTIES AND FLAVOUR ] sweet, sour and neutral. [ GUIJING ] GUIJING has effects of nourishing heart and small intestine. [ FUNCTIONS ] can induce diuresis to alleviate edema, remove toxicity and expel pus. Can be used for treating edema, swelling, tinea pedis, edema of limbs, jaundice, dark urine, rheumatism, pyretic arthralgia, carbuncle, suppurative sore, intestinal carbuncle, and abdominal pain.
And (3) rose: [ PROPERTIES AND WESTERN PROPERTIES ] is sweet, slightly bitter and warm. [ GUIJING ] enters liver and spleen meridians. [ FUNCTIONS ] can promote the circulation of qi, relieve depression, regulate blood circulation, and relieve pain. Can be used for treating liver and stomach qi pain, anorexia, emesis, menoxenia, traumatic injury, and pain.
China rose flower: [ PROPERTIES AND FLAVOUR ] sweet and warm. [ GUIJING ] enters liver meridian. [ FUNCTIONS ] can promote blood circulation to restore menstrual flow, and relieve swelling and remove toxic substance. It is indicated for irregular menstruation, abdominal pain due to menstruation, traumatic injury, swelling and pain due to blood stasis, abscess, deep-rooted carbuncle and toxic swelling.
Dried orange peel: [ PROPERTIES AND WESTERN ] is bitter, pungent and warm. [ GUIJING ] enters lung and spleen meridians. [ FUNCTIONS ] can regulate qi, invigorate spleen, eliminate dampness and resolve phlegm. Can be used for treating fullness in chest and abdomen, anorexia, vomiting, diarrhea, cough, and excessive phlegm.
Tuckahoe, poria cocos: [ PROPERTIES AND FLAVOUR ] sweet, bland and mild. [ GUIJING ] can enter heart, lung, spleen and kidney meridians. [ FUNCTIONS ] can induce diuresis, remove dampness, invigorate spleen, and tranquilize mind. Can be used for treating edema, oliguria, phlegm and fluid retention, dizziness, palpitation, spleen deficiency, anorexia, loose stool, diarrhea, uneasiness, palpitation, and insomnia.
Wolfberry fruit: [ PROPERTIES AND FLAVOUR ] sweet and neutral. [ GUIJING ] enters liver and kidney meridians. [ FUNCTIONS ] can nourish liver and kidney, replenish vital essence and improve eyesight. Can be used for treating asthenia, soreness of waist and knees, vertigo, tinnitus, internal heat, diabetes, blood deficiency, sallow complexion, and blurred vision.
Astragalus root: [ PROPERTIES AND FLAVOUR ] sweet and warm. [ GUIJING ] enters lung and spleen meridians. [ FUNCTIONS ] can tonify qi, strengthen superficies, induce diuresis, remove toxicity, expel pus, heal wound and promote granulation. Can be used for treating deficiency of vital energy, asthenia, anorexia, loose stool, collapse of middle-warmer energy, chronic diarrhea, rectocele, hematochezia, metrorrhagia, superficial deficiency, spontaneous perspiration, qi deficiency, edema, carbuncle, cellulitis, intractable ulcer, blood deficiency, debility with yellowish complexion, internal heat, and diabetes; proteinuria due to chronic nephritis and diabetes.
Cassia twig: [ PROPERTIES AND FLAVOUR ] pungent, sweet and warm. [ GUIJING ] GUIJING is responsible for the heart, lung and bladder meridians. [ FUNCTIONS ] can induce sweat, dispel muscles, warm and dredge meridians, strengthen yang, regulate qi, and calm the adverse flow of qi. Can be used for treating wind-cold type common cold, abdominal psychroalgia, blood cold amenorrhea, arthralgia, phlegm retention, edema, palpitation, and galloping.
Ligusticum wallichii: [ PROPERTIES AND FLAVOURS ]: pungent and warm. [ GUIJING ] enters liver, gallbladder and pericardium. [ Functional indications ]: promote blood circulation and move qi, dispel wind and alleviate pain. Can be used for treating menoxenia, amenorrhea, dysmenorrhea, abdominal pain, pricking pain in chest and hypochondrium, traumatic injury, swelling and pain, headache, and rheumatalgia.
Moutan bark: it is called as Dan Pi, bitter, pungent and slightly cold in property and flavor. [ GUIJING ] GUIJING is responsible for the heart, liver and kidney meridians. [ FUNCTIONS ] can clear heat and cool blood, promote blood circulation and remove blood stasis. Can be used for treating toxic heat, speckle, hematemesis, epistaxis, nocturnal fever, morning cool, anhidrosis, amenorrhea, dysmenorrhea, carbuncle, swelling, sore, traumatic injury, and pain.
Chinese angelica: [ PROPERTIES AND FLAVOUR ] sweet, pungent and warm. [ GUIJING ] enters liver, heart and spleen meridians. [ FUNCTIONS ] can tonify blood, promote blood circulation, regulate menstruation, relieve pain, moisten intestines and relieve constipation. Can be used for treating blood deficiency, sallow complexion, giddiness, palpitation, menoxenia, amenorrhea, dysmenorrhea, asthenia cold, abdominal pain, constipation due to intestinal dryness, rheumatic arthralgia, traumatic injury, superficial infection, pyocutaneous disease.
Fructus aurantii: [ PROPERTIES AND WESTERN ] is bitter, pungent, sour and warm in taste. [ GUIJING ] can enter spleen and stomach meridians. [ FUNCTIONS ] can regulate qi, relieve epigastric distention, remove food stagnation and relieve distension. Can be used for treating qi stagnation in chest and hypochondrium, fullness and pain, dyspepsia, and retention of phlegm and fluid; gastroptosis, rectocele, uterine prolapse.
Balloon flower: [ PROPERTIES AND WESTERN ] is bitter, pungent and mild. [ GUIJING ] enters lung meridian. [ FUNCTIONS ] can ventilate lung, relieve sore throat, dispel phlegm, and expel pus. Can be used for treating cough with excessive phlegm, chest distress, pharyngalgia, hoarseness, lung carbuncle, suppuration, and pyocutaneous disease with pus formation.
Turmeric root-tuber: [ PROPERTIES AND WESTERPHIES ] is pungent, bitter and cold in nature. [ GUIJING ] GUIJING enters liver, heart and lung meridians. [ FUNCTIONS ] can promote the circulation of qi, dispel blood stasis, clear away the heart-fire, relieve depression, promote the function of gallbladder, and relieve jaundice. Can be used for treating amenorrhea, dysmenorrhea, chest and abdomen distention and pain, pricking pain, fever unconsciousness, epilepsy, jaundice, and dark urine.
White peony root: [ PROPERTIES AND WESTERN PROPERTIES ] is bitter, sour and slightly cold. [ GUIJING ] enters liver and spleen meridians. [ FUNCTIONS ] can calm the liver, alleviate pain, nourish blood, regulate menstruation, astringe yin and stop sweating. Can be used for treating headache, vertigo, hypochondriac pain, abdominal pain, limb spasm and pain, blood deficiency, sallow complexion, menoxenia, spontaneous perspiration, and night sweat.
Red peony root: [ PROPERTIES AND FLAVOUR ] bitter and slightly cold. [ GUIJING ] enters liver meridian. [ FUNCTIONS ] can clear heat and cool blood, remove blood stasis and relieve pain. Can be used for treating macula due to toxic heat, hematemesis, epistaxis, conjunctival congestion, swelling and pain, liver depression, hypochondriac pain, amenorrhea, dysmenorrhea, abdominal pain, traumatic injury, carbuncle, swelling, and pyocutaneous disease.
And (3) allium macrostemon: [ PROPERTIES AND WESTERN ] is sweet, pungent, bitter and warm. [ GUIJING ] enters lung, stomach and large intestine meridians. [ FUNCTIONS ] can activate yang, dissipate stagnation, move qi and remove food stagnation. Can be used for treating thoracic obstruction and pain, cough and asthma due to phlegm-fluid retention, and diarrhea and tenesmus.
Citron: [ PROPERTIES AND WESTERN ] is pungent, bitter, sour and warm in flavor. [ GUIJING ] enters liver, spleen and lung meridians. [ FUNCTIONS ] can soothe the liver, regulate qi, relieve epigastric distention, and resolve phlegm. Can be used for treating qi stagnation of liver and stomach, distending pain in chest and hypochondrium, fullness and distention in stomach and abdomen, emesis, belching, excessive phlegm and cough.
Fingered citron: [ PROPERTIES AND FLAVOUR ] pungent, bitter, sour and warm. [ GUIJING ] enters liver, spleen and lung meridians. [ FUNCTIONS ] can soothe the liver, regulate qi, harmonize stomach, and alleviate pain. Can be used for treating qi stagnation of liver and stomach, distending pain in chest and hypochondrium, fullness and distention in stomach, anorexia, and emesis.
Lotus seed: [ PROPERTIES AND FLAVOUR ] sweet, astringent and neutral. [ GUIJING ] can enter spleen, kidney and heart meridians. [ FUNCTIONS ] can tonify spleen, check diarrhea, tonify kidney, astringe essence, nourish heart, and induce tranquilization. Can be used for treating spleen deficiency, chronic diarrhea, spermatorrhea, leukorrhagia, palpitation, and insomnia.
Astragalus root: [ PROPERTIES AND FLAVOUR ] sweet and warm. [ GUIJING ] enters lung and spleen meridians. [ FUNCTIONS ] can tonify qi, strengthen superficies, induce diuresis, remove toxicity, expel pus, heal wound and promote granulation. Can be used for treating deficiency of vital energy, asthenia, anorexia, loose stool, collapse of middle-warmer energy, chronic diarrhea, rectocele, hematochezia, metrorrhagia, superficial deficiency, spontaneous perspiration, qi deficiency, edema, carbuncle, cellulitis, intractable ulcer, blood deficiency, debility with yellowish complexion, internal heat, and diabetes; proteinuria due to chronic nephritis and diabetes.
Red sage root: [ PROPERTIES AND FLAVOUR ] bitter and slightly cold. [ GUIJING ] returning to the heart and liver meridians. [ FUNCTIONS ] can dispel blood stasis, relieve pain, promote blood circulation, dredge channels, clear away heart-fire and relieve restlessness. Can be used for treating menoxenia, amenorrhea, dysmenorrhea, abdominal mass, thoracico-abdominal pain, arthralgia due to heat, pyocutaneous disease, swelling and pain, vexation, and insomnia; hepatosplenomegaly, angina pectoris.
Radix pseudostellariae: [ PROPERTIES AND FLAVOUR ] sweet, slightly bitter and neutral. [ GUIJING ] can enter spleen and lung meridians. [ FUNCTIONS ] can replenish qi, invigorate the spleen, promote the production of body fluid and moisten the lung. Can be used for treating spleen deficiency, asthenia, deficiency of both qi and yin, spontaneous perspiration, thirst, and dry cough due to lung dryness.
Codonopsis pilosula: [ PROPERTIES AND FLAVOUR ] sweet and neutral. [ GUIJING ] can enter spleen and lung meridians. [ FUNCTIONS ] can tonify middle-jiao and qi, invigorate spleen and nourish lung. Can be used for treating spleen and lung deficiency, short breath, palpitation, anorexia, loose stool, asthma, cough, internal heat, and diabetes.
Sea-buckthorn: [ PROPERTIES AND WESTERN PROPERTIES ] is sweet, sour, astringent and warm. [ FUNCTIONS ] can relieve cough, dispel phlegm, promote digestion, remove food stagnation, promote blood circulation, and remove blood stasis. Can be used for treating cough with excessive phlegm, dyspepsia, abdominal pain due to dyspepsia, amenorrhea due to blood stasis, and traumatic injury with blood stasis and swelling.
Motherwort: cool in nature, pungent and bitter in flavor, entering heart and liver meridians; promoting blood circulation to regulate menstruation, inducing diuresis to alleviate edema. Can be used for treating menoxenia, dysmenorrhea, amenorrhea, lochiorrhea, edema, and oliguria; edema due to acute nephritis.
Pseudo-ginseng: [ PROPERTIES AND WESTERN PROPERTIES ] is sweet, slightly bitter and warm. [ GUIJING ] enters liver and stomach meridians. [ FUNCTIONS ] can dispel blood stasis, stop bleeding, relieve swelling, and relieve pain. Can be used for treating hemoptysis, hematemesis, epistaxis, hematochezia, metrorrhagia, traumatic hemorrhage, thoracico-abdominal pain, and traumatic swelling and pain.
Poria with hostwood: [ PROPERTIES AND FLAVOUR ] sweet and mild. [ FUNCTIONS ] can calm heart and induce tranquilization. It is suitable for palpitation, insomnia and amnesia.
E, donkey-hide gelatin: [ PROPERTIES AND FLAVOUR ] sweet and neutral. [ GUIJING ] enters lung, liver and kidney meridians. [ FUNCTIONS ] can tonify blood, nourish yin, moisten dryness and stop bleeding. Can be used for treating blood deficiency, sallow complexion, giddiness, cardiopalmus, muscle weakness, vexation, insomnia, deficient wind stirring, cough due to dryness of lung, overstrain cough, hemoptysis, hematemesis, hematuria, hematochezia, metrorrhagia, and gestational fetal leakage.
Gelatin: [ PROPERTIES AND FLAVOUR ] sweet in taste; the nature is mild. [ GUIJING ] enters lung and large intestine meridians. [ FUNCTIONS ] can nourish yin and moisten dryness; nourishing blood and stopping bleeding; promoting blood circulation and relieving swelling; and (5) detoxifying. Treating consumptive disease and consumptive lung disease; cough with hemoptysis; hematemesis and epistaxis; (ii) metrorrhagia and metrostaxis; diarrhea and hematochezia; traumatic injury; carbuncle, deep-rooted carbuncle and sore; burn and scald.
The active components of the traditional Chinese medicine composition for regulating and treating the blood stasis constitution comprise the following raw material medicines in parts by weight: 50-150 parts of radix rehmanniae, 50-150 parts of peach kernel, 80-130 parts of hawthorn, 80-120 parts of phaseolus calcaratus, 70-120 parts of rose, 80-130 parts of Chinese rose, 70-120 parts of dried orange peel, 80-120 parts of poria cocos, 80-120 parts of medlar, 300 parts of astragalus membranaceus, 50-70 parts of cassia twig, 80-120 parts of ligusticum wallichii, 80-130 parts of moutan bark, 70-230 parts of angelica, 180 parts of fructus aurantii 130, 80-120 parts of platycodon grandiflorum, 80-120 parts of radix curcumae, 50-150 parts of radix paeoniae alba, 80-130 parts of red paeony root, 80-120 parts of allium macrostemon, 80-120 parts of citron, 70-120 parts of fingered citron, 80-120 parts of lotus seed, 70-230 parts of salvia miltiorrhiza, 250 parts of heterophylly 150, 80-120 parts of codonopsis pilosula, 80-130 parts of sea, 190 parts of pseudo-ginseng 130 and 80-120 parts of poria with hostwood.
Furthermore, in the raw materials, the hawthorn is preferably raw hawthorn, and the astragalus is preferably raw astragalus.
Further, the raw materials are matched with 50-150 parts of donkey-hide gelatin, 300 parts of oxhide gelatin and 450 parts of maltose to prepare a plaster formula according to a conventional method, and the plaster formula accords with the Chinese medicine health preserving and health care technical operating specification (II) -plaster formula ZYXH \ T172-2010 of the Chinese medical society.
Example 1
The active components of the traditional Chinese medicine composition for regulating and treating the blood stasis constitution comprise the following raw material medicines in parts by weight: 50 parts of dried rehmannia root, 50 parts of peach kernel, 80 parts of raw hawthorn, 80 parts of red bean, 70 parts of rose, 80 parts of Chinese rose, 70 parts of dried orange peel, 80 parts of tuckahoe, 80 parts of medlar, 100 parts of raw astragalus root, 50 parts of cassia twig, 80 parts of hemlock parsley, 80 parts of moutan bark, 70 parts of angelica, 130 parts of bitter orange, 80 parts of platycodon root, 80 parts of turmeric root-tuber, 50 parts of white paeony root, 80 parts of red paeony root, 80 parts of allium macrostemon, 80 parts of citron, 70 parts of fingered citron, 80 parts of lotus seed, 150 parts of astragalus root, 70 parts of salvia miltiorrhiza, 150 parts of heterophylly falsestarwort root, 80 parts of codonopsis pilosula, 80 parts of sea-buckthorn, 130 parts of motherwort, 130 parts of pseudo-ginseng and 80 parts of poria.
Example 2
The active components of the traditional Chinese medicine composition for regulating and treating the blood stasis constitution comprise the following raw material medicines in parts by weight: 150 parts of dried rehmannia root, 150 parts of peach kernel, 130 parts of raw hawthorn, 120 parts of red bean, 120 parts of rose, 130 parts of Chinese rose, 120 parts of dried orange peel, 120 parts of tuckahoe, 120 parts of medlar, 300 parts of raw astragalus root, 70 parts of cassia twig, 120 parts of szechuan lovage rhizome, 130 parts of tree peony bark, 230 parts of angelica, 180 parts of bitter orange, 120 parts of platycodon root, 120 parts of turmeric root-tuber, 150 parts of white paeony root, 130 parts of red paeony root, 120 parts of allium macrostemon, 120 parts of citron, 120 parts of fingered citron, 120 parts of lotus seed, 250 parts of astragalus root, 230 parts of salvia miltiorrhiza, 250 parts of heterophylly falsestarwort root, 120 parts of pilose asiabell root, 130 parts of seabuckthorn fruit, 180 parts of motherwort, 190 parts of pseudo-ginseng, 120.
Example 3
The active components of the traditional Chinese medicine composition for regulating and treating the blood stasis constitution comprise the following raw material medicines in parts by weight: 100 parts of dried rehmannia root, 100 parts of peach kernel, 100 parts of raw hawthorn, 100 parts of red bean, 100 parts of rose, 100 parts of Chinese rose flower, 100 parts of dried orange peel, 100 parts of tuckahoe, 100 parts of medlar, 200 parts of raw astragalus root, 60 parts of cassia twig, 100 parts of szechuan lovage rhizome, 100 parts of tree peony bark, 150 parts of angelica, 150 parts of bitter orange, 100 parts of platycodon root, 100 parts of turmeric root-tuber, 100 parts of white paeony root, 100 parts of red paeony root, 100 parts of allium macrostemon, 100 parts of citron, 100 parts of fingered citron, 100 parts of lotus seed, 200 parts of astragalus root, 150 parts of salvia miltiorrhiza, 200 parts of heterophylly falsestarwort root, 100 parts of pilose asiabell root, 100 parts of sea-buckthorn, 150 parts of motherwort, 150 parts of pseudo-ginseng.
Example 4
The active components of the traditional Chinese medicine composition for regulating and treating the blood stasis constitution comprise the following raw material medicines in parts by weight: 100 parts of dried rehmannia root, 100 parts of peach kernel, 100 parts of raw hawthorn, 100 parts of red bean, 100 parts of rose, 100 parts of Chinese rose flower, 100 parts of dried orange peel, 100 parts of tuckahoe, 100 parts of medlar, 200 parts of raw astragalus root, 60 parts of cassia twig, 100 parts of szechuan lovage rhizome, 100 parts of tree peony bark, 150 parts of angelica, 150 parts of bitter orange, 100 parts of platycodon root, 100 parts of turmeric root-tuber, 100 parts of white paeony root, 100 parts of red paeony root, 100 parts of allium macrostemon, 100 parts of citron, 100 parts of fingered citron, 100 parts of lotus seed, 200 parts of astragalus root, 150 parts of salvia miltiorrhiza, 200 parts of heterophylly falsestarwort root, 100 parts of pilose asiabell root, 100 parts of sea-buckthorn, 150.
The Chinese medicinal composition of the invention is applied to clinic, and the treatment effect is as follows:
1. general data
180 patients with blood stasis constitutions are collected together, and diagnosis and recording are carried out according to the Chinese medicine society Standard "Classification and judgment of traditional Chinese medicine constitutions" ZYXH/T157-2009. The observation groups were randomly divided into 1 group, 2 groups and 3 groups, and 60 cases were observed in each group.
Observing 28 men and 32 women in 1 group, mean age (51.5 ± 24.2) years;
observing 29 men and 31 women in 2 groups, the mean age (50.3 ± 24.1) years;
3 groups of 30 men and 30 women were observed, the mean age (51.2. + -. 24.7) being the age of the year.
2. The treatment method and the treatment course are as follows: observing that 1-3 groups of the Chinese medicinal composition formula in the embodiment 1-3 are respectively taken correspondingly, the Chinese medicinal composition formula is taken twice a day, one spoon (about 15g) of boiled water is taken each time, the Chinese medicinal composition formula is taken in the morning and evening, 3 months are taken as 1 treatment course, and the Chinese medicinal composition formula is taken for 1-3 treatment courses.
3. The clinical manifestations are as follows: is suitable for treating dull complexion, blood stasis, pain, dull or purple lips, dark eye sockets, dry skin, dysmenorrhea, amenorrhea, etc.
4. Criteria for judging therapeutic effects
4.1 method for determining body constitution type
All questions in the Chinese medicinal constitution Classification and judgment Table (see appendix of Chinese medicinal constitution Classification and judgment) were answered, each question was scored according to 5 grades, the original score and the conversion score were calculated, and the type of constitution was judged according to the standard.
Adding original score to each item score
Conversion fraction [ (original fraction number of entries) (entry number 4) ] × 100
4.2 peace and quality criteria
The mild and mild constitutions are normal constitutions, and the other 8 constitutions are abnormal constitutions. Criteria are given in the following table
Figure BDA0002428967790000091
4.3 therapeutic grading
And (4) healing, namely the clinical symptoms of blood stasis basically disappear, and the peaceful and mild grades judge that the result is 'yes', and recovering normal life.
The method has the advantages that the clinical symptoms of blood stasis disappear partially, all physical signs are gradually improved, and the grading judgment result of the harmony and the quality is basically 'yes'.
No effect, no obvious improvement of symptom signs.
5. Therapeutic results
Figure BDA0002428967790000101
The clinical conditions show that the traditional Chinese medicine composition has an obvious effect on treating the blood stasis constitution, the cure rate is more than 85.0%, and the total effective rate is more than 96.7%.
6. Typical cases
Medical record 1
Huang Zhi, female, age 45, first diagnosis. Patient complaints are: the facial color spots are remained for 6 years. The patients begin to have color spots on the faces 6 years ago, the treatment effects are poor after the treatment of skin care, freckle removal and the like in a plurality of beauty parlors, and the outpatient service of the hospital is now required for the system treatment. The symptoms are as follows: the face is scattered in dark red spots, mainly around cheeks and canthus, and the rest face and body skin are dry, accompanied by lower limb desquamation, dark lip color, insomnia and dreamful sleep, good appetite, small stool and dry stool. Dysmenorrhea, profuse blood clots, purple and dark menses, and good menstrual flow and period. Dark tongue with thin and white coating and wiry and unsmooth pulse. And (3) Western diagnosis: chloasma. Traditional Chinese medicine constitution identification (Chinese medical society standard): constitutions of blood stasis; diagnosis of traditional Chinese medicine diseases: liver spots; syndrome type of internal stagnation of blood stasis. 1 course of treatment (3 months) is taken twice a day, one spoon (about 15g) of the traditional Chinese medicine composition paste formula in the embodiment 3 of the invention is taken with boiled water, and the traditional Chinese medicine composition paste formula is taken in the morning and at night.
In the second diagnosis, after the patient takes the ointment formula, the color spots on the face are reduced, the color becomes light, the face skin is glossy earlier, the body skin is dry and better, the lower limbs have no obvious desquamation, the lips are ruddy earlier, and the sleep is better. Pain during menstruation was relieved, blood clots were reduced, and the color of menstruation was dark red. Dark red tongue with thin and white coating and wiry and unsmooth pulse. The Chinese medicinal composition of the invention in the embodiment 3 is continuously taken for 1 course of treatment (3 months), and the administration method is the same as before.
For the third diagnosis, after the patient takes the ointment formula, the facial color spots basically disappear, the body skin does not have dryness and desquamation, the lips are ruddy, and no dysmenorrhea exists. It is identified as mild constitution by the constitution of traditional Chinese medicine. Order to eat less raw and cold food. After 1 year, the test still shows that the body is healthy and mild.
Medical record 2
Xia in summer, male, 38 years old, first diagnosis. Patient complaints are: pain all over the body for more than 3 years. The patient falls from a high place 3 years ago to have a plurality of fractures of the whole body, after the patient is actively treated by an outer hospital, the fracture part is well healed, the activity is as usual, but the patient is always accompanied with the general pain and discomfort, the fracture part is obvious, but the examination has no obvious abnormality. Now, the doctor visits the clinic to seek the systemic treatment. The symptoms are as follows: general pain, fracture as the main part, obvious night, difficult sleep, dark face and lips, dark eye circles, good diet, dry mouth but not drinking water, purple and dark tongue with thin and white coating, wiry and unsmooth pulse. And (3) Western diagnosis: pain is caused. Traditional Chinese medicine constitution identification (Chinese medical society standard): constitutions of blood stasis; diagnosis of traditional Chinese medicine diseases: arthralgia syndrome; syndrome type of internal stagnation of blood stasis. The traditional Chinese medicine composition tea drink of the embodiment 4 of the invention is taken twice a day for 1 treatment course (3 months), 15g of the tea drink is taken with boiled water every time, and the tea drink is taken in the morning and the evening.
In the second diagnosis, after the patient takes the tea, the pain of the whole body is relieved, the sleep is improved, the color of the lips and the eyes of the face is dark, the eye is blackened, the mouth is dry at night, the tongue is dark red, the coating is thin and white, and the pulse is wiry. The traditional Chinese medicine composition tea of the embodiment 4 of the invention is continuously taken for 1 course of treatment (3 months), and the taking method is the same as before.
For the three diagnostic methods, patients have no pain all over the body after drinking the tea, and do not make any more at night, and the rest diseases are removed. It is identified as mild constitution by the constitution of traditional Chinese medicine. After 1 year, the test still shows that the body is healthy and mild.
7. Observation of adverse reactions
In the treatment and observation cases, patients with adverse reactions are not found, which shows that the traditional Chinese medicine composition is safe and reliable.
The traditional Chinese medicine composition can be prepared into pills, pellets, decoction, granules, capsules and oral liquid by a conventional method, and is applied to conditioning the blood stasis constitution, namely the traditional Chinese medicine composition can be applied to preparing the medicine for conditioning the blood stasis constitution.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like made within the spirit and principle of the present invention should be included in the scope of the present invention.

Claims (7)

1. The traditional Chinese medicine composition for regulating and treating the blood stasis constitution is characterized by comprising the following active components in parts by weight: 50-150 parts of radix rehmanniae, 50-150 parts of peach kernel, 80-130 parts of hawthorn, 80-120 parts of phaseolus calcaratus, 70-120 parts of rose, 80-130 parts of Chinese rose, 70-120 parts of dried orange peel, 80-120 parts of poria cocos, 80-120 parts of medlar, 300 parts of astragalus membranaceus, 50-70 parts of cassia twig, 80-120 parts of ligusticum wallichii, 80-130 parts of moutan bark, 70-230 parts of angelica, 180 parts of fructus aurantii 130, 80-120 parts of platycodon grandiflorum, 80-120 parts of radix curcumae, 50-150 parts of radix paeoniae alba, 80-130 parts of red paeony root, 80-120 parts of allium macrostemon, 80-120 parts of citron, 70-120 parts of fingered citron, 80-120 parts of lotus seed, 70-230 parts of salvia miltiorrhiza, 250 parts of heterophylly 150, 80-120 parts of codonopsis pilosula, 80-130 parts of sea, 190 parts of pseudo-ginseng 130 and 80-120 parts of poria with hostwood.
2. The traditional Chinese medicine composition for regulating and treating blood stasis constitutions according to claim 1, wherein active components thereof comprise the following raw material medicines in parts by weight: 95-105 parts of radix rehmanniae, 95-105 parts of peach kernel, 95-105 parts of raw hawthorn, 95-105 parts of phaseolus calcaratus, 95-105 parts of rose, 95-105 parts of Chinese rose, 95-105 parts of dried orange peel, 95-105 parts of poria cocos, 95-105 parts of wolfberry fruit, 190-containing astragalus root, 55-65 parts of cassia twig, 95-105 parts of ligusticum wallichii, 95-105 parts of moutan bark, 160 parts of angelica 140-containing materials, 160 parts of fructus aurantii 140-containing materials, 95-105 parts of platycodon grandiflorum, 95-105 parts of radix curcumae, 95-105 parts of white paeony root, 95-105 parts of red paeony root, 95-105 parts of allium macrostemon, 95-105 parts of citron, 95-105 parts of fingered citron, 95-105 parts of lotus seed, 160 parts of salvia miltiorrhiza 140-containing materials, 210 parts of radix pseudostellariae 190-containing materials, 95-105 parts of codonopsis, 140 portions of notoginseng and 160 portions of poria with hostwood 95-105 portions.
3. The traditional Chinese medicine composition for regulating and treating blood stasis constitutions according to claim 1, wherein active components thereof comprise the following raw material medicines in parts by weight: 100 parts of dried rehmannia root, 100 parts of peach kernel, 100 parts of hawthorn, 100 parts of phaseolus calcaratus, 100 parts of rose, 100 parts of Chinese rose flower, 100 parts of dried orange peel, 100 parts of tuckahoe, 100 parts of medlar, 200 parts of astragalus root, 60 parts of cassia twig, 100 parts of ligusticum wallichii, 100 parts of moutan bark, 150 parts of angelica, 150 parts of bitter orange, 100 parts of platycodon grandiflorum, 100 parts of radix curcumae, 100 parts of white paeony root, 100 parts of red paeony root, 100 parts of allium macrostemon, 100 parts of citron, 100 parts of fingered citron, 100 parts of lotus seed, 150 parts of salvia miltiorrhiza, 200 parts of radix pseudostellariae, 100 parts of codonopsis pilosula, 100 parts of sea.
4. The traditional Chinese medicine composition for regulating and treating blood stasis constitution according to claim 1, wherein the hawthorn is raw hawthorn, and the astragalus is raw astragalus.
5. A traditional Chinese medicine composition preparation for conditioning blood stasis constitution is characterized by comprising the traditional Chinese medicine composition for conditioning blood stasis constitution according to any one of claims 1-4, wherein the traditional Chinese medicine composition preparation is one of a paste formula, a tea drink, a pill, a pellet, a decoction, a granule, a capsule and an oral liquid.
6. The traditional Chinese medicine composition paste for conditioning blood stasis constitution is characterized by comprising the traditional Chinese medicine composition for conditioning blood stasis constitution according to any one of claims 1-4, and further comprising the following raw materials in parts by weight: 50-150 parts of donkey-hide gelatin, 300 parts of yellow gelatin and 450 parts of maltose.
7. The application of the traditional Chinese medicine composition for conditioning blood stasis constitutions, disclosed by any one of claims 1 to 6, in preparation of medicines for conditioning blood stasis constitutions.
CN202010229897.0A 2020-03-27 2020-03-27 Traditional Chinese medicine composition for regulating and treating blood stasis constitution and preparation and application thereof Pending CN111388625A (en)

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CN114432410A (en) * 2021-12-28 2022-05-06 上海中医药大学附属曙光医院 Blood-activating and stasis-removing ointment formula and application thereof

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CN101683503A (en) * 2008-09-27 2010-03-31 天津市中宝制药有限公司 Traditional Chinese medicine composition for nourishing heart and strengthening heart
CN103784820A (en) * 2014-02-23 2014-05-14 曹小松 Traditional Chinese medicine formula for treating cariac blood stasis type coronary heart disease
CN108014243A (en) * 2017-12-26 2018-05-11 慈中华 For nursing one's health the Chinese herbal ointment formula and its processing method of blood stasis constitution

Patent Citations (3)

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CN101683503A (en) * 2008-09-27 2010-03-31 天津市中宝制药有限公司 Traditional Chinese medicine composition for nourishing heart and strengthening heart
CN103784820A (en) * 2014-02-23 2014-05-14 曹小松 Traditional Chinese medicine formula for treating cariac blood stasis type coronary heart disease
CN108014243A (en) * 2017-12-26 2018-05-11 慈中华 For nursing one's health the Chinese herbal ointment formula and its processing method of blood stasis constitution

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114432410A (en) * 2021-12-28 2022-05-06 上海中医药大学附属曙光医院 Blood-activating and stasis-removing ointment formula and application thereof

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