CN105535552A - Traditional Chinese medicine oral liquid for improving immunity of human bodies and preparation method of traditional Chinese medicine oral liquid - Google Patents

Traditional Chinese medicine oral liquid for improving immunity of human bodies and preparation method of traditional Chinese medicine oral liquid Download PDF

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Publication number
CN105535552A
CN105535552A CN201610121841.7A CN201610121841A CN105535552A CN 105535552 A CN105535552 A CN 105535552A CN 201610121841 A CN201610121841 A CN 201610121841A CN 105535552 A CN105535552 A CN 105535552A
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China
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parts
chinese medicine
oral liquid
medicine oral
radix
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Inventor
胡镜宙
单泽松
任国欣
鞠侯雨
田卓炜
张志愿
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Ninth Peoples Hospital Shanghai Jiaotong University School of Medicine
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Ninth Peoples Hospital Shanghai Jiaotong University School of Medicine
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/062—Ascomycota
    • A61K36/066—Clavicipitaceae
    • A61K36/068—Cordyceps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/074—Ganoderma
    • A—HUMAN NECESSITIES
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/80—Scrophulariaceae (Figwort family)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8965—Asparagus, e.g. garden asparagus or asparagus fern
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    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969—Polygonatum (Solomon's seal)
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/898—Orchidaceae (Orchid family)
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Abstract

The invention discloses a traditional Chinese medicine oral liquid for improving immunity of human bodies and a preparation method of the traditional Chinese medicine oral liquid. The traditional Chinese medicine oral liquid is prepared from raw materials in parts by weight as follows: 18-26 parts of membranous milkvetch roots, 10-20 parts of Chinese red dates, 8-16 parts of Echinacea purpurea, 12-18 parts of agaric, 15-25 parts of dendrobium candidum, 10-20 parts of herba dendrobii loddigesii, 14-22 parts of anoectochilus roxburghii, 9-18 parts of raspberries, 5-15 parts of polygonatum, 20-30 parts of cochinchnese asparagus roots, 10-20 parts of Jinshen flowers, 11-17 parts of rehmannia roots, 15-25 parts of fructus lycii, 10-20 parts of herba Longshen, 25-35 parts of ginseng, 16-24 parts of lucid ganoderma, 15-25 parts of fragrant solomonseal rhizomes, 12-18 parts of emblic leafflower fruits, 18-26 parts of burdock roots and 20-30 parts of cordyceps flowers. According to the traditional Chinese medicine oral liquid for improving immunity of human bodies, the membranous milkvetch roots, the Chinese red dates, the Echinacea purpurea, the agaric, the dendrobium candidum, the herba dendrobii loddigesii and the various medicines are scientifically and reasonably matched, the medicine efficacy is improved due to the mutual synergistic or resistant function, the immunity is remarkably improved, and the health condition of the human bodies is improved. The traditional Chinese medicine oral liquid is convenient to use, safe and reliable, does not have any side effects or cause any poor reaction, and meets requirements of people.

Description

A kind of Chinese medicine oral liquid strengthening body immunity and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine oral liquid strengthening body immunity and preparation method thereof, belong to technical field of Chinese medicines.
Background technology
Immunity is the defense mechanism of human body self, is human bioequivalence and any foreign body (virus, antibacterial etc.) eliminating external intrusion.Process is old and feeble, damage, the ability of mutant cell and virus infected cell in the own cells of dead, degeneration and identification and handling body; be human bioequivalence and eliminate a pipe protection wall of external intrusion foreign body, it is whether sick that the height of immunity is directly linked to human body.Along with the continuous quickening of rhythm of life and continuing to increase of operating pressure, the immunity of people is more and more lower, and child personated old man is sick, young people always catches a cold, old man's physical weakness.Take a fancy to this phychology of people just, in recent years, market seized one after another by the various health product and the Chinese medicine that are turned on the advertising words such as " raising immunity ", " enhancing immunity ", " immunologic function adjustment " on the market, but great majority also exist the shortcoming of weak effect, even without any effect, cannot satisfy the demands of consumers.
Summary of the invention
The object of the invention is to for the deficiencies in the prior art, a kind of Chinese medicine oral liquid strengthening body immunity and preparation method thereof is provided.Chinese medicine oral liquid good drug efficacy of the present invention, enhancing immunity effect is obvious, can effectively improve people's body health level, meet the demand of people.
For achieving the above object, the present invention adopts following technical scheme:
Strengthen a Chinese medicine oral liquid for body immunity, be made up of the raw material of following weight portion: Radix Astragali 18-26, Fructus Jujubae 10-20, SONGGUOJU 8-16, Polyporus 12-18, Herba Dendrobii 15-25, dendrobium loddigesii Rolfe 10-20, Herba Anoectochili roxburghii 14-22, Fructus Rubi 9-18, Rhizoma Polygonati 5-15, Radix Asparagi 20-30, golden shen flower 10-20, Radix Rehmanniae 11-17, Fructus Lycii 15-25, dragon ginseng careless 10-20, Radix Ginseng 25-35, Ganoderma 16-24, Rhizoma Polygonati Odorati 15-25, Fructus Phyllanthi 12-18, Radix Arctii 18-26, Cordyceps 20-30.
Preferably, strengthen a Chinese medicine oral liquid for body immunity, be made up of the raw material of following weight portion: the Radix Astragali 22, Fructus Jujubae 15, SONGGUOJU 12, Polyporus 16, Herba Dendrobii 20, dendrobium loddigesii Rolfe 15, Herba Anoectochili roxburghii 18, Fructus Rubi 12, Rhizoma Polygonati 10, Radix Asparagi 25, golden shen spend 15, Radix Rehmanniae 14, Fructus Lycii 20, dragon ginseng grass 15, Radix Ginseng 30, Ganoderma 19, Rhizoma Polygonati Odorati 20, Fructus Phyllanthi 16, Radix Arctii 22, Cordyceps 25.
Strengthen a preparation method for the Chinese medicine oral liquid of body immunity, comprise the following steps:
(1) each raw material is taken by formulation ratio, pulverized 50-100 mesh sieve respectively, then mix homogeneously, add the water being equivalent to medicated powder 8-12 times amount, be heated to 60-70 DEG C, 4500-5500r/min high-speed stirred 15-25min, leave standstill 1-2h again, then boiling is heated to, insulation 2-3h, filter, filtering residue adds the water of 7-9 times amount again, be heated to 75-85 DEG C, lixiviate 1.5-2.5h, filter, merge lixiviating solution, being concentrated into relative density is 1.12-1.15, then adding 70% ethanol makes concentrated solution alcohol content be 45-55%, the centrifugal 20-30min of 3000-4000r/min, supernatant is got after leaving standstill 24-36h, isopyknic pure water is added in solution after decompression recycling ethanol, the centrifugal 30-40min of 2000-3000r/min, then cold preservation 12-24h at 4-6 DEG C of temperature, get supernatant, stand-by, ,
(2) add appropriate syrup by medicinal liquid obtained for step (1), stir, filter, fill, sterilizing, gets product.
Beneficial effect of the present invention:
The multi-medicaments such as the Radix Astragali, Fructus Jujubae, SONGGUOJU, Polyporus, Herba Dendrobii, dendrobium loddigesii Rolfe pass through to coordinate scientifically and rationally by the present invention, utilize the collaborative or resistant function that it is mutual, improve drug effect, make enhancing immunity effect obvious, thus improve the health level of people's health.And Chinese medicine oral liquid of the present invention is easy to use, safe and reliable, without any side effects, without any untoward reaction, meet the demand of people.
Detailed description of the invention
Embodiment 1
Strengthen a Chinese medicine oral liquid for body immunity, be made up of the raw material of following weight (g): the Radix Astragali 18, Fructus Jujubae 10, SONGGUOJU 8, Polyporus 12, Herba Dendrobii 15, dendrobium loddigesii Rolfe 10, Herba Anoectochili roxburghii 14, Fructus Rubi 9, Rhizoma Polygonati 5, Radix Asparagi 20, golden shen spend 10, Radix Rehmanniae 11, Fructus Lycii 15, dragon ginseng grass 10, Radix Ginseng 25, Ganoderma 16, Rhizoma Polygonati Odorati 15, Fructus Phyllanthi 12, Radix Arctii 18, Cordyceps 20.
Strengthen a preparation method for the Chinese medicine oral liquid of body immunity, comprise the following steps:
(1) each raw material is taken by formulation ratio, pulverized 50 mesh sieves respectively, then mix homogeneously, add the water being equivalent to medicated powder 8 times amount, be heated to 60 DEG C, 4500r/min high-speed stirred 25min, leave standstill 1h again, then boiling is heated to, insulation 2h, filter, filtering residue adds the water of 7 times amount again, be heated to 75 DEG C, lixiviate 1.5h, filter, merge lixiviating solution, being concentrated into relative density is 1.12, then adding 70% ethanol makes concentrated solution alcohol content be 45%, the centrifugal 30min of 3000r/min, supernatant is got after leaving standstill 24h, isopyknic pure water is added in solution after decompression recycling ethanol, the centrifugal 40min of 2000r/min, then cold preservation 12h at 4 DEG C of temperature, get supernatant, stand-by,
(2) add appropriate syrup by medicinal liquid obtained for step (1), stir, filter, fill, sterilizing, gets product.
Embodiment 2
Strengthen a Chinese medicine oral liquid for body immunity, be made up of the raw material of following weight (g): the Radix Astragali 22, Fructus Jujubae 15, SONGGUOJU 12, Polyporus 16, Herba Dendrobii 20, dendrobium loddigesii Rolfe 15, Herba Anoectochili roxburghii 18, Fructus Rubi 12, Rhizoma Polygonati 10, Radix Asparagi 25, golden shen spend 15, Radix Rehmanniae 14, Fructus Lycii 20, dragon ginseng grass 15, Radix Ginseng 30, Ganoderma 19, Rhizoma Polygonati Odorati 20, Fructus Phyllanthi 16, Radix Arctii 22, Cordyceps 25.
Strengthen a preparation method for the Chinese medicine oral liquid of body immunity, comprise the following steps:
(1) each raw material is taken by formulation ratio, pulverized 80 mesh sieves respectively, then mix homogeneously, add the water being equivalent to medicated powder 10 times amount, be heated to 65 DEG C, 5000r/min high-speed stirred 20min, leave standstill 1.5h again, then boiling is heated to, insulation 2.5h, filter, filtering residue adds the water of 8 times amount again, be heated to 80 DEG C, lixiviate 2h, filter, merge lixiviating solution, being concentrated into relative density is 1.13, then adding 70% ethanol makes concentrated solution alcohol content be 50%, the centrifugal 25min of 3500r/min, supernatant is got after leaving standstill 32h, isopyknic pure water is added in solution after decompression recycling ethanol, the centrifugal 35min of 2500r/min, then cold preservation 20h at 5 DEG C of temperature, get supernatant, stand-by,
(2) add appropriate syrup by medicinal liquid obtained for step (1), stir, filter, fill, sterilizing, gets product.
Embodiment 3
Strengthen a Chinese medicine oral liquid for body immunity, be made up of the raw material of following weight (g): the Radix Astragali 26, Fructus Jujubae 20, SONGGUOJU 16, Polyporus 18, Herba Dendrobii 25, dendrobium loddigesii Rolfe 20, Herba Anoectochili roxburghii 22, Fructus Rubi 18, Rhizoma Polygonati 15, Radix Asparagi 30, golden shen spend 20, Radix Rehmanniae 17, Fructus Lycii 25, dragon ginseng grass 20, Radix Ginseng 35, Ganoderma 24, Rhizoma Polygonati Odorati 25, Fructus Phyllanthi 18, Radix Arctii 26, Cordyceps 30.
Strengthen a preparation method for the Chinese medicine oral liquid of body immunity, comprise the following steps:
(1) each raw material is taken by formulation ratio, pulverized 100 mesh sieves respectively, then mix homogeneously, add the water being equivalent to medicated powder 12 times amount, be heated to 70 DEG C, 5500r/min high-speed stirred 15min, leave standstill 2h again, then boiling is heated to, insulation 3h, filter, filtering residue adds the water of 9 times amount again, be heated to 85 DEG C, lixiviate 1.5h, filter, merge lixiviating solution, being concentrated into relative density is 1.15, then adding 70% ethanol makes concentrated solution alcohol content be 55%, the centrifugal 20min of 4000r/min, supernatant is got after leaving standstill 36h, isopyknic pure water is added in solution after decompression recycling ethanol, the centrifugal 30min of 3000r/min, then cold preservation 24h at 6 DEG C of temperature, get supernatant, stand-by,
(2) add appropriate syrup by medicinal liquid obtained for step (1), stir, filter, fill, sterilizing, gets product.
Model case:
Case 1: Zhao, man, 38 years old.Within nearly 1 month, because dizzy brain weight has appearred in work fatigue, fear of cold is afraid of cold, loose stool, knee joint soreness, and particularly winter, symptom increased the weight of especially.Take Chinese medicine oral liquid of the present invention after 2 weeks, dizzy brain heavily alleviates, and knee joint soreness alleviates, and stool is normal; Following the service is after 2 weeks, and all diseases disappear entirely, recovers normal.
Case 2: Wang, female, 29 years old.In delicate health from childhood, always easy to catch cold at ordinary times.Feel malaise in daily life, discomfort tired out, or see and breathe hard, hyperhidrosis, aggravation after motion.After taking oral liquid of the present invention January, times of common cold significantly reduces, energetic in daily life, loses and breathes hard, hyperhidrosis.
Case 3: Zhang, man, 17 years old, there is dry cough without phlegm, feverish sensation in the palms and soles because of college entrance examination pressure of entering a higher school in nearly half a year, particularly night dysphoria with smothery sensation, dry mouth and parching tongue, is hard and dry, soreness of waist night sweat.Take oral liquid of the present invention after 10 days, cough reduces, and following the service is after 15 days, and cough disappears, and other malaise symptoms also disappears thereupon.

Claims (3)

1. one kind strengthens the Chinese medicine oral liquid of body immunity, it is characterized in that, be made up of the raw material of following weight portion: Radix Astragali 18-26, Fructus Jujubae 10-20, SONGGUOJU 8-16, Polyporus 12-18, Herba Dendrobii 15-25, dendrobium loddigesii Rolfe 10-20, Herba Anoectochili roxburghii 14-22, Fructus Rubi 9-18, Rhizoma Polygonati 5-15, Radix Asparagi 20-30, golden shen flower 10-20, Radix Rehmanniae 11-17, Fructus Lycii 15-25, dragon ginseng careless 10-20, Radix Ginseng 25-35, Ganoderma 16-24, Rhizoma Polygonati Odorati 15-25, Fructus Phyllanthi 12-18, Radix Arctii 18-26, Cordyceps 20-30.
2. a kind of Chinese medicine oral liquid strengthening body immunity according to claim 1, it is characterized in that, be made up of the raw material of following weight portion: the Radix Astragali 22, Fructus Jujubae 15, SONGGUOJU 12, Polyporus 16, Herba Dendrobii 20, dendrobium loddigesii Rolfe 15, Herba Anoectochili roxburghii 18, Fructus Rubi 12, Rhizoma Polygonati 10, Radix Asparagi 25, golden shen spend 15, Radix Rehmanniae 14, Fructus Lycii 20, dragon ginseng grass 15, Radix Ginseng 30, Ganoderma 19, Rhizoma Polygonati Odorati 20, Fructus Phyllanthi 16, Radix Arctii 22, Cordyceps 25.
3. the preparation method strengthening the Chinese medicine oral liquid of body immunity as claimed in claim 1 or 2, is characterized in that, comprise the following steps:
Each raw material is taken by formulation ratio, pulverized 50-100 mesh sieve respectively, then mix homogeneously, add the water being equivalent to medicated powder 8-12 times amount, be heated to 60-70 DEG C, 4500-5500r/min high-speed stirred 15-25min, leave standstill 1-2h again, then boiling is heated to, insulation 2-3h, filter, filtering residue adds the water of 7-9 times amount again, be heated to 75-85 DEG C, lixiviate 1.5-2.5h, filter, merge lixiviating solution, being concentrated into relative density is 1.12-1.15, then adding 70% ethanol makes concentrated solution alcohol content be 45-55%, the centrifugal 20-30min of 3000-4000r/min, supernatant is got after leaving standstill 24-36h, isopyknic pure water is added in solution after decompression recycling ethanol, the centrifugal 30-40min of 2000-3000r/min, then cold preservation 12-24h at 4-6 DEG C of temperature, get supernatant, stand-by,
(2) add appropriate syrup by medicinal liquid obtained for step (1), stir, filter, fill, sterilizing, gets product.
CN201610121841.7A 2016-03-04 2016-03-04 Traditional Chinese medicine oral liquid for improving immunity of human bodies and preparation method of traditional Chinese medicine oral liquid Pending CN105535552A (en)

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