CN103721020A - Blood circulation promoting and meridian unlocking granule for treating cerebral thrombosis and preparation method of granule - Google Patents

Blood circulation promoting and meridian unlocking granule for treating cerebral thrombosis and preparation method of granule Download PDF

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Publication number
CN103721020A
CN103721020A CN201310707631.2A CN201310707631A CN103721020A CN 103721020 A CN103721020 A CN 103721020A CN 201310707631 A CN201310707631 A CN 201310707631A CN 103721020 A CN103721020 A CN 103721020A
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China
Prior art keywords
parts
radix
granule
cerebral thrombosis
herba
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Pending
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CN201310707631.2A
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Chinese (zh)
Inventor
王东祥
强泽明
陈永恒
罗燕
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Anhui Jintaiyang Biochemical Medicine Co Ltd
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Anhui Jintaiyang Biochemical Medicine Co Ltd
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Priority to CN201310707631.2A priority Critical patent/CN103721020A/en
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Abstract

The invention discloses blood circulation promoting and meridian unlocking granule for treating cerebral thrombosis and a preparation method of the granule. The granule is prepared from the following raw materials in parts by weight: 30-50 parts of root of red-rooted salvia, 25-35 parts of pseudo-ginseng, 15-20 parts of rhizome of chuanxiong, 20-30 parts of peach kernel, 10-15 parts of herba pyrolae, 30-40 parts of gardeniae, 15-25 parts of loranthus parasiticu, 20-30 parts of rheum officinale, 10-15 parts of concha haliotidis, 16-22 parts of astragalus membranaceus, 40-50 parts of herba epimedii, 18-24 parts of wild jujube leaf, 30-40 parts of tuber fleeceflower stem, 15-25 parts of rhizoma acori graminei, 18-24 parts of ginseng flower, 20-30 parts of radix asparagi, 24-32 parts of folium cortex eucommiae, 20-25 parts of uncaria, 10-20 parts of oenothera biennis, 15-25 parts of immature bitter orange and 20-30 parts of scutellaria baicalensis. The granule disclosed by the invention has functions of benefiting qi and blood, nourishing heart and dispelling wind, relaxing sinews and unlocking the meridians, and activating blood to unlock the meridians, and the granule is effective in treatment, rapid to take effect, short in treatment course, high in cure rate, free from side effect and recurrence after healing; the granule solves the problems of an existing medicine for treating cerebral thrombosis which is long in treatment course, slow to become effective, difficult to cure and serious in toxic and side effect.

Description

A kind of blood circulation and channel invigorating electuary for the treatment of cerebral thrombosis and preparation method thereof
Technical field
The present invention relates to a kind of blood circulation and channel invigorating electuary for the treatment of cerebral thrombosis and preparation method thereof, belong to the field of Chinese medicines.
Background technology
Cerebral thrombosis is to supply outward on the basis of arterial blood tube wall generation pathologic change of brain at intracranial, in the situations such as slow blood flow, blood constituent change or blood viscosity increase, forms thrombosis.It is numb that patient's premorbid has limbs, the sign such as ineffective, the slurred speech of moving, dizzy, blurred vision.Often in sleep in or morbidity morning, suffering limb activity is unable or stiff, speak ambiguous or aphasia, drink water send out choke.Most patients realize elimination or slight obstacle.Nervus facialis and hypoglossal paralysis, nystagmus, muscular tension and abdomen hyporeflexia or enhancing, the pathologic reflex positive, stomach wall and cremasteric reflex weaken or disappear.The slight person of cerebral thrombosis shows as that a side limb activity is dumb, insensitive, error, and severe patient can occur that stupor, gatism are even dead.Western medicine adopts dilatation and vasodilations such as adopting torental, Senc, flunarizine more at present, and expanding blood volume reduces blood viscosity, improves the blood circulation of brain, prevents red blood cell condensation.But this class drug side effect is large, there will be headache, feel sick, the untoward reaction such as vomiting or disturbance of consciousness.Although Chinese medicine preparation side effect is little, also exist uncertain therapeutic efficacy and cut, the course for the treatment of is long, cures the problems such as slow.
Summary of the invention
The object of the invention is to for the deficiencies in the prior art, a kind of blood circulation and channel invigorating electuary for the treatment of cerebral thrombosis and preparation method thereof is provided, this curative effect of medication is remarkable, instant effect, and short treating period, cure rate is high, is difficult for recurrence, has no side effect, and has no adverse reaction.
For achieving the above object, the present invention adopts following technical scheme:
Treat a Radix Notoginseng TONGMAI CHONGJI for cerebral thrombosis, by the raw material of following weight portion, made: Radix Salviae Miltiorrhizae 30-50, Radix Notoginseng 25-35, Rhizoma Chuanxiong 15-20, Semen Persicae 20-30, Herba Pyrolae 10-15, Fructus Gardeniae 30-40, Herba Taxilli 15-25, Radix Et Rhizoma Rhei 20-30, Concha Haliotidis 10-15, Radix Astragali 16-22, Herba Epimedii 40-50, Folium Ziziphi Spinosae 18-24, Caulis Polygoni Multiflori 30-40, Rhizoma Acori Graminei 15-25, Flos Ginseng 18-24, Radix Asparagi 20-30, Folium Eucommiae 24-32, Ramulus Uncariae Cum Uncis 20-25, Radix Oenotherae erythrosepalae 10-20, Fructus Aurantii Immaturus 15-25, Radix Scutellariae 20-30.
Preferably, treat a Radix Notoginseng TONGMAI CHONGJI for cerebral thrombosis, by the raw material of following weight portion, made: Radix Salviae Miltiorrhizae 40, Radix Notoginseng 30, Rhizoma Chuanxiong 20, Semen Persicae 25, Herba Pyrolae 15, Fructus Gardeniae 35, Herba Taxilli 20, Radix Et Rhizoma Rhei 25, Concha Haliotidis 15, the Radix Astragali 18, Herba Epimedii 40, Folium Ziziphi Spinosae 22, Caulis Polygoni Multiflori 35, Rhizoma Acori Graminei 20, Flos Ginseng 22, Radix Asparagi 25, Folium Eucommiae 28, Ramulus Uncariae Cum Uncis 20, Radix Oenotherae erythrosepalae 15, Fructus Aurantii Immaturus 20, Radix Scutellariae 25.
A preparation method for the treatment of the blood circulation and channel invigorating electuary of cerebral thrombosis, comprises the following steps:
(1) get above-mentioned Chinese medicine and add the 5-8 times of micro-decoction 40-50min that boils of water gaging, filter, retain filtrate; Medicinal residues add 4-6 times of micro-the boiling of water gaging again and decoct 30-40min, and merging filtrate after filtering, is condensed into the 1/3-1/2 of original volume, then adds 95% ethanol, makes it contain alcohol amount and reaches 60-70%, and standing 24-36h, gets supernatant, and heating is concentrated into extractum shape;
(2) the above-mentioned extractum making adds the sucrose of 2-3% and the dextrin of 3-5%, and mix homogeneously adds appropriate 95% ethanol moistening, granulates, and 50-60 ℃ of dry 10-15min, crosses 15-20 mesh sieve, subpackage, and every bag 10g, is finished product.
Beneficial effect of the present invention:
Medicine of the present invention is according to the theoretical thought of the determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs of venting QI-blood, live meridians, reinforcing unit, health body and clinical experience is formulated for many years, there is benefiting QI and nourishing blood, nourish heart dispel the wind, the effect of meridians dredging, blood circulation and channel invigorating, evident in efficacy, instant effect, short treating period, cure rate is high, have no side effect, have no adverse reaction, do not recur after more, the medicine that has solved existing treatment cerebral thrombosis exist the course for the treatment of long, take effect slow, can not cure, problem that toxic and side effects is large.
The specific embodiment
treat a Radix Notoginseng TONGMAI CHONGJI for cerebral thrombosis, by the raw material of following weight (g), made: Radix Salviae Miltiorrhizae 40, Radix Notoginseng 30, Rhizoma Chuanxiong 20, Semen Persicae 25, Herba Pyrolae 15, Fructus Gardeniae 35, Herba Taxilli 20, Radix Et Rhizoma Rhei 25, Concha Haliotidis 15, the Radix Astragali 18, Herba Epimedii 40, Folium Ziziphi Spinosae 22, Caulis Polygoni Multiflori 35, Rhizoma Acori Graminei 20, Flos Ginseng 22, Radix Asparagi 25, Folium Eucommiae 28, Ramulus Uncariae Cum Uncis 20, Radix Oenotherae erythrosepalae 15, Fructus Aurantii Immaturus 20, Radix Scutellariae 25.
A preparation method for the treatment of the blood circulation and channel invigorating electuary of cerebral thrombosis, comprises the following steps:
(1) get above-mentioned Chinese medicine and add 6 times of micro-decoction 45min that boil of water gaging, filter, retain filtrate; Medicinal residues add 4 times of micro-boiling of water gaging again and decoct 30min, and merging filtrate after filtering, is condensed into 1/2 of original volume, then adds 95% ethanol, makes it contain alcohol amount and reaches 70%, and standing 36h, gets supernatant, and heating is concentrated into extractum shape;
(2) the above-mentioned extractum making adds 2% sucrose and 4% dextrin, and mix homogeneously, adds appropriate 95% ethanol moistening, granulates, and 50 ℃ of dry 15min, cross 20 mesh sieves, subpackage, and every bag 10g, is finished product.
Model case:
Case 1: poplar, female, 74 years old.First visit on October 18 in 2011.Main suit: recurrent dizziness, forgetful.A few days ago, without obviously inducement appearance dizziness, nauseating, vomiting, companion's left limb is unable.Health check-up: blood pressure 130/85, isocoria is sensitive to luminous reflectance.Auxiliary examination: triglyceride is higher.Tentative diagnosis is: brain atrophy, cerebral thrombosis.Taken electuary of the present invention, every day 3 times, each 10g, warm water is taken after mixing it with water, and takes after 7 days, and malaise symptoms is clearly better, and continues to take after 10 days, and malaise symptoms disappears, and it is strong that body is felt, blood pressure, triglyceride indices recover normal on inspection.Follow up a case by regular visits to not recurrence so far.
Case 2: Hao, man, 58 years old.First visit on August 22 in 2011.Main suit: headache throughout the year.3 days there is discontinuity moving obstacle in front right upper and lower extremities.Readme is waken up morning, and right side disorder of limb ' s activity without other discomforts, but recovers very soon.Do not pay attention to.There is again this situation afternoon.Through examination in hospital, be cerebral thrombosis, take Nifedipine Tablets, poor effect.So taken electuary of the present invention, every day 3 times, each 10g, warm water is taken after mixing it with water, and takes after 15 days, and malaise symptoms disappears, and all recover normal.Follow up a case by regular visits to not recurrence so far.
Case 3: Song, 62 years old.First visit on April 16 in 2011.Bimester before happen suddenly and spit out white foams, left side upper and lower extremities loses movable function companion facial hemiparalysis, delivers to immediately hospital, through examination in hospital, is burst cerebral thrombosis, after hospitalization 10 days is invalid, leaves hospital and goes home, the here of leaving hospital over the 3rd day is medical.Check: blood pressure 140/70, left side upper and lower extremities afunction, facial hemiparalysis.Taken electuary of the present invention, every day 3 times, each 10g, warm water is taken after mixing it with water, and takes after 10 days, and left side upper and lower extremities function is clearly better, and a mouthful eye recovers normal, continues to take after 10 days, and left side upper and lower extremities functional rehabilitation is normal, recovery from illness.Follow up a case by regular visits to not recurrence so far.

Claims (3)

1. treat the Radix Notoginseng TONGMAI CHONGJI of cerebral thrombosis for one kind, it is characterized in that, by the raw material of following weight portion, made: Radix Salviae Miltiorrhizae 30-50, Radix Notoginseng 25-35, Rhizoma Chuanxiong 15-20, Semen Persicae 20-30, Herba Pyrolae 10-15, Fructus Gardeniae 30-40, Herba Taxilli 15-25, Radix Et Rhizoma Rhei 20-30, Concha Haliotidis 10-15, Radix Astragali 16-22, Herba Epimedii 40-50, Folium Ziziphi Spinosae 18-24, Caulis Polygoni Multiflori 30-40, Rhizoma Acori Graminei 15-25, Flos Ginseng 18-24, Radix Asparagi 20-30, Folium Eucommiae 24-32, Ramulus Uncariae Cum Uncis 20-25, Radix Oenotherae erythrosepalae 10-20, Fructus Aurantii Immaturus 15-25, Radix Scutellariae 20-30.
2. a kind of Radix Notoginseng TONGMAI CHONGJI for the treatment of cerebral thrombosis according to claim 1, it is characterized in that, by the raw material of following weight portion, made: Radix Salviae Miltiorrhizae 40, Radix Notoginseng 30, Rhizoma Chuanxiong 20, Semen Persicae 25, Herba Pyrolae 15, Fructus Gardeniae 35, Herba Taxilli 20, Radix Et Rhizoma Rhei 25, Concha Haliotidis 15, the Radix Astragali 18, Herba Epimedii 40, Folium Ziziphi Spinosae 22, Caulis Polygoni Multiflori 35, Rhizoma Acori Graminei 20, Flos Ginseng 22, Radix Asparagi 25, Folium Eucommiae 28, Ramulus Uncariae Cum Uncis 20, Radix Oenotherae erythrosepalae 15, Fructus Aurantii Immaturus 20, Radix Scutellariae 25.
3. the preparation method of the blood circulation and channel invigorating electuary for the treatment of cerebral thrombosis according to claim 1, is characterized in that comprising the following steps:
(1) get above-mentioned Chinese medicine and add the 5-8 times of micro-decoction 40-50min that boils of water gaging, filter, retain filtrate; Medicinal residues add 4-6 times of micro-the boiling of water gaging again and decoct 30-40min, and merging filtrate after filtering, is condensed into the 1/3-1/2 of original volume, then adds 95% ethanol, makes it contain alcohol amount and reaches 60-70%, and standing 24-36h, gets supernatant, and heating is concentrated into extractum shape;
(2) the above-mentioned extractum making adds the sucrose of 2-3% and the dextrin of 3-5%, and mix homogeneously adds appropriate 95% ethanol moistening, granulates, and 50-60 ℃ of dry 10-15min, crosses 15-20 mesh sieve, subpackage, and every bag 10g, is finished product.
CN201310707631.2A 2013-12-20 2013-12-20 Blood circulation promoting and meridian unlocking granule for treating cerebral thrombosis and preparation method of granule Pending CN103721020A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105311384A (en) * 2015-10-20 2016-02-10 安徽金太阳生化药业有限公司 Traditional Chinese medicine decoction for treating cerebral thrombosis and preparation method thereof
CN106138532A (en) * 2016-08-04 2016-11-23 马畅 The inducing resuscitation for the treatment of cerebral infarction is removed obstacles Chinese medicine and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1686510A (en) * 2005-04-14 2005-10-26 赵宏伟 Ready prepared Chinese medicine for preventing and treating brain apoplexia

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1686510A (en) * 2005-04-14 2005-10-26 赵宏伟 Ready prepared Chinese medicine for preventing and treating brain apoplexia

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105311384A (en) * 2015-10-20 2016-02-10 安徽金太阳生化药业有限公司 Traditional Chinese medicine decoction for treating cerebral thrombosis and preparation method thereof
CN106138532A (en) * 2016-08-04 2016-11-23 马畅 The inducing resuscitation for the treatment of cerebral infarction is removed obstacles Chinese medicine and preparation method thereof

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Application publication date: 20140416