CN105535353A

CN105535353A - Externally used medicine for treating pathogen-infective abnormal leukorrhea

Info

Publication number: CN105535353A
Application number: CN201610088036.9A
Authority: CN
Inventors: 吴淑芬
Original assignee: Individual
Current assignee: Individual
Priority date: 2016-02-17
Filing date: 2016-02-17
Publication date: 2016-05-04

Abstract

The invention discloses an externally used medicine for treating pathogen-infective abnormal leucorrhea. The externally used medicine is prepared from, by weight, 18-30 parts of a sweet wormwood herb, 18-30 parts of licorice roots, 18-30 parts of pseudo-ginsengs, 18-30 parts of a capillary wormwood herb, 18-30 parts of radix scutellariae, 18-30 parts of hawthorn fruits, 18-30 parts of fructus rosae laevigatae, 18-30 parts of radix geutianae, 6-20 parts of gordon euryale seeds, 6-20 parts of gingkoes, 6-20 parts of plantain seeds, 6-20 parts of paeonia lactiflora, 6-20 parts of cyperus rotundus, 6-20 parts of Chinese torreya seeds, 6-20 parts of gemma agrimoninae, 6-20 parts of giant knotweeds, 6-20 parts of radix sanguisorbae, 6-20 parts of cotton rose leaves and 6-20 parts of herba aristolochiae. The Chinese herbal medicines can quickly kill common pathogens of pathogen-infective abnormal leucorrhea, meanwhile does not destroy existing endovaginal beneficial bacteria and has the remarkable curative effect on the pathogen-infective abnormal leucorrhea.

Description

A kind of external used medicine for the treatment of pathogenic infection leucorrhea exception

Technical field

The present invention relates to a kind of medicine, be specifically related to a kind of external used medicine for the treatment of pathogenic infection leucorrhea exception.

Background technology

Leucorrhea is the secretions that intravaginal is discharged, and it is not only the natural cover for defense of women, keeps the moistening of vagina, the material of the invasion of anti-pain relieving substance, but also is healthy one side " mirror ", can reflect the health status of health.Amount seldom under normal circumstances, and color is white, band stickiness, odorless, the epidermis cell of the mucus inside having cervix uteri to secrete, the exudate of vaginal mucosa, uterus and vaginal prolapse, and a small amount of leukocyte and non-pathogenic bacterium vaginae etc.

Leucorrhea abnormal is a kind of general gynecological inflammation seen, long-standing problem numerous women, the change of common leucorrhea abnormal mainly on leucorrhea amount, color, matter, taste.Leucorrhea abnormal mainly contains two types: 1, physiological leucorrhea abnormal.Healthy women leucorrhoea grow in quantity increases to body inner estrogen level and is directly proportional.As the onset of ovulation or trimester of pregnancy leucorrhoea grow in quantity, when in uterus film grows long, or application estrogenic after all can there is leucorrhoea grow in quantity.2, pathologic leucorrhea abnormal.The leucorrhea abnormal that colpitis, chronic cervicitis, senile vaginitis, endometritis, fluid in uterine or foreign body in vagina, hysteromyoma, genital herpes, gonorrhea, condyloma acuminatum, uterine prolapse, chronic pelvic inflammatory disease etc. cause, and the leucorrhea abnormal caused by pathogenic infection.Wherein, the leucorrhea abnormal caused by pathogenic infection is one of modal leucorrhea abnormal reason.Use pollute hygienic article, make pathogen per vaginam mouth enter reproductive tract, infect; Women goes to toilet, if the direction of wiping toilet paper is not right, also the antibacterial of anus may be taken to reproductive tract and cause infection.At present, abnormal for pathogenic infection leucorrhea, carry out sterilizing mainly through Western medicine and reach therapeutic effect, but while killing leucorrhea abnormal disease-producing pathogens, also killed intravaginal probiotics, especially lactobacillus, destroyed the self-purification function of vagina., Western medicine easily causes stimulation to vagina simultaneously.Market also exists some treatment pathogenic infection leucorrheas abnormal, mainly Chinese herbal medicine for oral administration, although obtain certain therapeutic effect, but Chinese herbal medicine for oral administration can produce certain side effect to human body.

Summary of the invention

For above deficiency, the invention provides a kind of external used medicine for the treatment of pathogenic infection leucorrhea exception, it overcomes the deficiency of Western medicine and the drawback of Chinese herbal medicine for oral administration, leucorrhea abnormal common causative can be killed fast, and intravaginal lactobacillus can not be killed, do not destroy the original environment of vagina, have no side effect.

The present invention for the taked technical scheme that solves the problem is:

Treat an external used medicine for pathogenic infection leucorrhea exception, be made up of the raw material of following weight portion: Herba Artemisiae Annuae 18 ~ 30 parts, 18 ~ 30 parts, Radix Glycyrrhizae, Radix Notoginseng 18 ~ 30 parts, Herba Artemisiae Scopariae 18 ~ 30 parts, Radix Scutellariae 18 ~ 30 parts, Fructus Crataegi 18 ~ 30 parts, Fructus Rosae Laevigatae 18 ~ 30 parts, Radix Gentianae 18 ~ 30 parts, Semen Euryales 6 ~ 20 parts, Semen Ginkgo 6 ~ 20 parts, Semen Plantaginis 6 ~ 20 parts, Radix Paeoniae 6 ~ 20 parts, Rhizoma Cyperi 6 ~ 20 parts, Semen Torreyae 6 ~ 20 parts, Bud of hairyvein agrimony 6 ~ 20 parts, Rhizoma Polygoni Cuspidati 6 ~ 20 parts, Radix Sanguisorbae 6 ~ 20 parts, Folium Hibisci Mutabilis 6 ~ 20 parts, Herba Aristolochiae 6 ~ 20 parts.

Preferably, the external used medicine of described treatment pathogenic infection leucorrhea exception is made up of the raw material of following weight portion: Herba Artemisiae Annuae 22 ~ 28 parts, 22 ~ 28 parts, Radix Glycyrrhizae, Radix Notoginseng 22 ~ 28 parts, Herba Artemisiae Scopariae 22 ~ 28 parts, Radix Scutellariae 22 ~ 28 parts, Fructus Crataegi 22 ~ 28 parts, Fructus Rosae Laevigatae 22 ~ 28 parts, Radix Gentianae 22 ~ 28 parts, Semen Euryales 8 ~ 15 parts, Semen Ginkgo 8 ~ 15 parts, Semen Plantaginis 8 ~ 15 parts, Radix Paeoniae 8 ~ 15 parts, Rhizoma Cyperi 8 ~ 15 parts, Semen Torreyae 8 ~ 15 parts, Bud of hairyvein agrimony 8 ~ 15 parts, Rhizoma Polygoni Cuspidati 8 ~ 15 parts, Radix Sanguisorbae 8 ~ 15 parts, Folium Hibisci Mutabilis 8 ~ 15 parts, Herba Aristolochiae 8 ~ 15 parts.

More preferably, the external used medicine of described treatment pathogenic infection leucorrhea exception, is made up of the raw material of following weight portion: Herba Artemisiae Annuae 25 parts, 25 parts, Radix Glycyrrhizae, Radix Notoginseng 25 parts, Herba Artemisiae Scopariae 25 parts, Radix Scutellariae 25 parts, Fructus Crataegi 25 parts, Fructus Rosae Laevigatae 25 parts, Radix Gentianae 25 parts, Semen Euryales 10 parts, Semen Ginkgo 10 parts, Semen Plantaginis 10 parts, Radix Paeoniae 10 parts, Rhizoma Cyperi 10 parts, Semen Torreyae 10 parts, Bud of hairyvein agrimony 10 parts, Rhizoma Polygoni Cuspidati 10 parts, Radix Sanguisorbae 10 parts, Folium Hibisci Mutabilis 10 parts, Herba Aristolochiae 10 parts.

The dosage form of Chinese herbal medicine of the present invention can be the medically acceptable dosage form such as lotion, suppository, spray, and their preparation method, supplementary product consumption are undertaken by existing common process.

The drug effect principle of each component of the present invention is as follows:

Herba Artemisiae Annuae is the dry aerial parts of feverfew Herba Artemisiae Annuae ArtemisiaannuaL..Bud stage is gathered, and extracts aerial parts, and chopping, dries.Ancient name " Qin " (q ì n).Clearing away summer-heat, except steaming, preventing the attack (or recurrence) of malaria.For pathogenic summer-heat heating, fever due to yin deficiency, night fever abating at dawn, hectic fever due to YIN-deficiency consumptive fever, malaria cold and heat, jaundice due to damp-heat.It is a kind of antimalarial drug of cheapness.

Radix Glycyrrhizae, (formal name used at school: GlycyrrhizauralensisFisch) is called: state is old, Herba Hedyotis cantonensis, Glycyrrhiza uralensis Fisch., sweet root.Pulse family, Glycyrrhiza perennial herb, root and root stock sturdy, be a kind of tonification Chinese herbal medicine.To the good a kind of medicine of human body, medicinal part is root and rhizome.Radix Glycyrrhizae contains number of chemical composition, and main component has glycyrrhizic acid, liquiritin etc.The chemical composition of Radix Glycyrrhizae is very complicated, and from Radix Glycyrrhizae, isolated compound has the tens of kinds of compounds such as glycyrrhizin, enoxolone, liquiritin, isoliquiritin, neoliquriitin, neoisoliquiritin, glycyrrhizin, isoliquiritigenin and licoricidin (+)-Licoricidin., glycyrol, isoglycyrol, 7-methylcoumarin essence, umbelliferone so far.Effect: 1, for insufficiency of heart-QI, severe palpitation, irregularly intermittent and regularly intermittent pulse, and deficiency of spleen-QI and stomach-QI, fatigue and weakness etc.The former, normal and Ramulus Cinnamomi compatibility, as Ramuli Cinnamomi and Glycyrrhizae Decoction, zhigancao decoction.The latter, is often equal to use with Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, as ball in decoction of four noble drugs, reason etc.2, for ulcer sores, laryngopharynx swelling and pain etc.Can be alone, for oral administration or external application, or compatibility application.Ulcer sores, is often equal to use with Flos Lonicerae, Fructus Forsythiae, plays the merit of heat-clearing and toxic substances removing altogether, as Xian fang Huoming Yin.Laryngopharynx swelling and pain, the normal and same use of Radix Platycodonis, as Radix Platycodonis decoction.If pesticide, alimentary toxicosis, often join Semen phaseoli radiati or be decocted in water for oral dose with Radix Saposhnikoviae.3, for asthma and cough.Can be alone, also can the application of compatibility other drug.As controlled the ERCHEN TANG of cough due to damp-phlegm; Control the Linggan Wuwei Jiangxin Tang of cold-phlegm cough with asthma; Control the sangxing decoction of dry stool phlegm cough; Control pyretic toxicity and cause lung abscess cough and spit and to smell as of rotten fish the Radix Platycodonis decoction of purulent sputum; Control the Gancao Ganjiang soup etc. of cough and spit saliva foam.The also Chang Peiwu application of another cough due to pathogenic wind-heat, cough due to wind and cold, phlegm heat cough.

Radix Notoginseng, Chinese medicine name.For the dry root welding technology of panax araliaceae plant Panaxnotoginseng (Burk.) F.H.Chen.Cure mainly: for spitting of blood, spit blood, epistaxis, has blood in stool, metrorrhagia, traumatic hemorrhage, breast ventral spine pain, tumbling and swelling.

Herba Artemisiae Scopariae, another name Adeps Bovis seu Bubali, Tian Naili, because of dirt, Ma Xian, capillary wormwood, floss Artemisia, Herba Artemisiae Sieversianae, spire Herba Artemisiae Annuae, An Lvcao, Latin literary fame ArtemisiacapillarisThunb. tubular flower order, Compositae, origanum Artemisia are dead through the winter, old of Chun Zeyin and giving birth to, therefore named because of old or Herba Artemisiae Scopariae.Then Artemisia is become to its Seedling of summer, therefore also known as Herba Artemisiae Scopariae.Herba Artemisiae Scopariae clearing away heat-damp and promoting diuresis; Jaundice eliminating.Cure mainly: jaundice, dysuria, eczema pruritus, infectious jaundice type hepatitis.Pharmaceutical research has function of gallbladder promoting, liver function protecting, antipyretic, antiinflammatory, blood fat reducing, blood pressure lowering, the effects such as coronary dilating.

Radix Scutellariae (Classification system: ScutellariabaicalensisGeorgi), another name Radix Scutellariae, tsuchikane tea root are Labiatae Scutellaria herbaceos perennials.The root of Radix Scutellariae is used as medicine, bitter in the mouth, cold in nature, has heat clearing and damp drying, eliminating fire and detoxication, hemostasis, the effect such as antiabortive.Pharmacological action: 1, antibacterial action: Radix Scutellariae decoct 100% concentration, flat band method is tested, inhibitory action is had to dysentery bacterium, Bacillus typhi, Salmonella paratyphi, vibrio cholera, escherichia coli, Bacillus proteus, bacillus pyocyaneus, staphylococcus, hemolytic vessel used to hold grain at the imperial sacrifice coccus (a, B), Diplococcus pneumoniae, diphtheria corynebacterium etc.Radix Scutellariae decoct test tube method test 1:1280 concentration can suppress Bacillus typhi, Hemolytic streptococcus a, 1:640 control of the concentration Hemolytic streptococcus B, Diplococcus pneumoniae and shigella flexneri, bacillus tuberculosis typus humanus H37,1:320 concentration can suppress vibrio cholera, dysentery bacterium; During 1:80 concentration, sonne bacillus has inhibitory action.Radix Scutellariae alcohol immersion 0.5g/ml or 0.05g/ml, cultivate with agar slant, medicinal liquid mixes with culture medium 1:1, has inhibitory action to bacillus pyocyaneus.Radix Scutellariae alcohol immersion 2g/ml concentration, Plating test has inhibitory action to escherichia coli, Fructus Citri tangerinae grass bacillus, staphylococcus aureus.Radix Scutellariae decoct, alcohol extraction agent 1g/ml concentration, all have to meningococcus the effect of pressing down when testing by flat band method.2, antifungic action: Radix Scutellariae decocting liquid, test tube slant method tests 4% control of the concentration Canis familiaris L. denticle born of the same parents bacterium and trichophyton, 8% control of the concentration oidium schoenleinii, the mutation of 10% control of the concentration oidium schoenleinii Mongolia, 15% control of the concentration homocentricity trichophyton and rust trichophyton.Radix Scutellariae water logging agent 1:3 concentration is in vitro to trichophyton, Trichophyton concentricunm, and oidium schoenleinii, Microsporon audouini, Pilus Caprae seu Ovis sample microspore tinea bacterium, epidermophyton rubrum, K, W, family name epidermophyton, star nocardia etc. have bacteriostasis in various degree.3, antivirus action: Radix Scutellariae decoct 25-100% concentration, in vitro tests has copied inhibitory action to hepatitis B virus DNA.[5]

Fructus Crataegi (CrataeguspinnatifidaBunge), have another name called fruit, Fructus Pyri Pashiae in mountain, Rosaceae Crataegus, stone fruit, caryoplasm is hard, and sarcocarp is thin, and taste is micro-sour and astringent.Fruit is raw-eaten or make preserved fruit fruitcake, can be used as medicine after drying, Chinese distinctive medicine fruit dual-purpose seeds, there is the effects such as blood fat reducing, blood pressure, heart tonifying, arrhythmia, also be simultaneously the good medicine of spleen benefiting and stimulating the appetite, relieving dyspepsia, phlegm reduction of blood circulation promoting, the disease such as, hernia, blood stasis full to chest and diaphragm spleen, amenorrhea has good curative effect.Flavone compound vitexin in Fructus Crataegi is the medicine that a kind of antitumaous effect is stronger, and its extract all has certain effect to growth of cancer cells, propagation and infiltration metastasis in suppression body.

Fructus Rosae Laevigatae, Chinese medicine name.For the dry mature fruit of rosaceous plant Fructus Rosae Laevigatae RosalaevigataMichx..There is controlling nocturnal emission with astringent drugs reducing urination, stopping metrorrhagia and leukorrhagia, effect of relieving diarrhea with astringents.Be usually used in emission and spermatorrhea, enuresis frequent micturition, bleeding not during menses, chronic diarrhea chronic dysentery.

Radix Gentianae, original name: Radix Gentianae, another name: Radix Gentianae, careless Radix Gentianae, Eumeces Chinensis gallbladder, Latin literary fame: GentianascabraBunge. Gentianaceae, Gentiana perennial herb.Effect: antibacterial action tries 14 kinds of agueweeds, wherein 7 pairs of root nodule bacterias, escherichia coli, bacillus subtilis, Agrobacterium tumefaciens etc. have effect.Radix Gentianae water logging agent has inhibitory action in various degree to dermatophytess such as trichophyton gypseum star nocardias in vitro.Test tube method proves that Radix Gentianae decoct is to bacillus pyocyaneus, and Bacillus proteus, Bacillus typhi, dysentery bacterium, staphylococcus aureus etc. have inhibitory action in various degree.Cure mainly: heat clearing and damp drying; Eliminating pathogen in the liver is calmed the frightened.Jaundice due to damp-heat; Urine leaching pain; Swelling of the vulva pudendal pruritus; Damp-heat vaginal discharge; The feeling of fullness in the head headache of liver and gall excess-fire; Conjunctival congestion and swelling pain; Deaf ear swells; Hypochondriac pain bitter taste; Calentura convulsion with spasms.

Semen Euryales, annual large-scale aquatic and herbaceous.Effect: supplementing the kidney to control the nocturnal, spleen reinforcing antidiarrheal, eliminating dampness and arresting leucorrhea.Cure mainly: for emission and spermatorrhea, enuresis frequent micturition, insufficiency of the spleen chronic diarrhea, nebulousurine, leukorrhagia.

Semen Ginkgo (formal name used at school: Ginkgobiloba), has another name called duck bottom sediment, mental eye, Ginkgo biloba Linn.cv.Fozhi Citrus chachiensis Hort., Semen Ginkgo, Gong Sunshuzi, is the kernel of Semen Ginkgo.Semen Ginkgo kernel is except containing except starch, protein, fat, saccharide, also containing trace element and ginkgoic acid, bilobol, five carbon polysaccharide such as vitamin C, riboflavin, carotene, calcium, phosphorus, ferrum, potassium, magnesium, the compositions such as fat sterin, nutritious, and for lung benefiting gas, control cough with asthma, leukorrhagia stopping worm, urine reducing, flat chapped wrinkle, protect blood vessel, increase the diseases such as blood flow, leukorrhagia, nebulousurine there is good medical effect and dietary function.

Semen Plantaginis is the another name of Big Semen Plantaginis, Herba Plantaginis, Plantago depressa Willd, beach Herba Plantaginis, buckhorn plantain; Medicinal Semen Plantaginis is the dry mature seed of Plantaginaceae plant Herba Plantaginis or Plantago depressa Willd.Effect: enter kidney, urinary bladder channel.1. " book on Chinese herbal medicine covers bamboo fish trap ": " enter bladder." 2. " Thunder God concocts property of medicine solution ": " enter liver, bladder, small intestinal three warp." 3. " Bencao Jingshu ": " enter kidney, liver, bladder three warp." curing mainly: diuretic, heat clearing away, improving eyesight, eliminates the phlegm.Control urinary obstruction, stranguria with turbid discharge, leukorrhagia, hematuria, heat-damp in summer dysentery, cough ant phlegm, arthralgia chiefly caused by damp pathogen, conjunctival congestion is hidden from view.

Radix Paeoniae (formal name used at school: PaeonialactifloraPall.), another name will from, from grass, belong to Dilleniales, Ranunculaceae [1] Paeonia perennial herb flowers.The fresh and crisp succulence of root of Radix Paeoniae, can hyoscine.According to analysis, Peony Root contains paeoniflorin and benzoic acid, and purposes is different because of kind.The traditional Chinese medical science is thought: the Radix Paeoniae Alba in Chinese medicine mainly refers to the root of Radix Paeoniae, and it has spasmolytic, eases pain, the effect of stimulating the menstrual flow.To diseases such as the stomachache of women, stomach spasm, dizzy, gout, diuresis effectively [13].

Rhizoma Cyperi, Chinese medicine name.For the dry rhizome of sedge dried tuber.Effect: dispersing the stagnated live-QI to relieve the stagnation of QI, regulating the flow of QI to ease the stomach, menstruction regulating and pain relieving.Cure mainly: for stagnation of QI due to depression of the liver, distending pain in the chest and hypochondrium, hernia pain, distending pain of the breast, stagnation of QI in spleen and stomach, gastral cavity abdomen painful abdominal mass is vexed, distension pain, menoxenia, amenorrhea dysmenorrhea.

Semen Torreyae, also known as Chinese torreya, red fruit, Yushan fruit, beautiful Chinese torreya, open country extremely son etc., be the seed of a kind of taxaceae plant, cure mainly: 1. treat ancylostomiasis. eat every day fry Semen Torreyae 3 ~ 5 liang, until confirmation stool in worm's ovum disappear till.Once controlled 5 examples (wherein 3 examples have whipworm concurrently), all fully recovered through about January.Control no side effects in journey.This product is as coordinated Fructus Quisqualis meat, garlic clove decoction, then curative effect is better.2. filaricide is treated. get Semen Torreyae meat 5 liang, crinis carbonisatus (Crinis Carbonisatus ash) 1 liang, grinds mixing into powder and adjusts honey to be twisted into 150 balls.Day takes 3 times, each 2 balls, is a course for the treatment of with 4 days.Clinical observation 20 example, after first course for the treatment of microfilariae of ohchocerciasis turn out cloudy 4 example, turn out cloudy after second course for the treatment of 9 example, all the other most of patients also have improvement in various degree.Control in journey except having slight dizziness after 1 example is taken medicine, other all have no adverse reaction.Tentatively think that this product has certain effect to killing microfilariae of ohchocerciasis.

Bud of hairyvein agrimony, dicotyledon Rosaceae.Herbaceos perennial, Herb tool white becomes mildewed.Composition: containing agrimophol, agrimonol, 4',5,7-trihydroxyflavone, catechol, tannin etc.Agrimophol is phloroglucinol analog derivative, now can synthetic, is the effective ingredient of cestode of going out." the southern regions of the Yunnan Province book on Chinese herbal medicine ": " medical treatment married woman's menstruation or before or after, redly collapse leucorrhea [1], the cold back of the body in face is cold, lumbago, heating flatulence, dysentery.”

Rhizoma Polygoni Cuspidati, Chinese medicine name.For dry rhizome and the root of polygonaceae plant Rhizoma Polygoni Cuspidati PolygonumcuspidatumSieb.etZucc..Spring, Qiu Erji excavate, and removing fibrous root, cleans, take advantage of short section of fresh-cut or sheet, dry.Be distributed in the ground such as northwest, East China, Central China, south China and southwest.There is dampness removing jaundice eliminating, heat-clearing and toxic substances removing, eliminating stasis to stop pain, effect of relieving cough and resolving phlegm.For jaundice due to damp-heat, stranguria with turbid discharge, leukorrhagia, rheumatic arthralgia, carbuncle sore tumefacting virus, burn due to hot liquid or fire, amenorrhea, lump in the abdomen, instep plays damage, cough due to lung-heat.

Radix Sanguisorbae (Classification system: SanguisorbaofficinalisL.) is Rosaceae burnet herbaceos perennial, and spindle is sturdy follows, short handle lobule, and aubergine petal, fruit contains in calyx tube.Another name " yellow pawl is fragrant ", " beautiful letter ", " beautiful fermented soya beans, salted or other wise " or " acid is reddish brown " etc.Radix Sanguisorbae is also Chinese herbal medicine.Cold in nature, bitter in the mouth acid, nontoxic; Return liver, lung, kidney and large intestine channel.There is cooling blood for hemostasis, heat-clearing and toxic substances removing, train clear yin nourishing, the effects such as detumescence sore.

Folium Hibisci Mutabilis, machaka or dungarunga, effect: 1. " Bencao Tujing ": " toxic swelling of applying ointment or plaster." 2. " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " can bind round skin ulcer and lift one's head." 3. " detailed outline ": " Qingfei Liangxue, heat radiation removing toxic substances.Control all size swollen ulcer drug malignant boil, detumescence and apocenosis pain relieving." 4. " beautiful Chinese catalpa medicine solution ": " fresh breeze expels the heat-evil, and removing heat from blood is subsided a swelling." 5. " conventional glossary of Herbs and Drugs among the people ": " external synthetism." cure mainly: removing heat from blood, removing toxic substances, detumescence, pain relieving.Control Yong Ju burning swelling, be burdened with herpes zoster, scalds, conjunctival congestion and swelling pain, traumatic injury.

Herba Aristolochiae, stem is elongated cylindrical, slightly distortion, diameter 1 ~ 3mm; Surface yellow green or khaki, has vertical rib and joint, internode Length discrepancy; Matter is crisp, frangibility, and section has several vascular bundle differed in size.Leaf alternate, many shrinkages, fragmentation, in the narrow avette or triangular shape width egg shape of triangular shape after intact leaf flattens, base portion is heart-shaped, dirty-green or khaki, and basal leaf veinclearing shows, and petiole is elongated, gas delicate fragrance, lightly seasoned.Effect: 1, antiinflammatory action: the impact on mice capillary permeability: the increasing of induced mice capillary of skin permeability of Fructus Aristolochiae 10g/kg to 20ul/ intradermal injection histamine (50ug/ml) has obvious inhibitory action.Rat inflammatory is oozed out and the impact of hypertrophy: Fructus Aristolochiae can not suppress inflammatory exudation caused by Fructus Crotonis and hypertrophy.The impact of hypertrophy that rat granuloma is swollen: Fructus Aristolochiae swells hamartoplasia without obvious inhibitory action to rat granuloma.2, antibacterial action: in vitro tests Fructus Aristolochiae water logging agent (1:4) has certain inhibitory action to common skin fungus.Fresh Aristolochia contorta fruit and leaf have inhibitory action to staphylococcus aureus in vitro, and the effect of fruit is stronger than leaf, and still effective after removing tannin, after heating, antibacterial action lowers or loses, to bacillus pyocyaneus without effect.

Beneficial effect of the present invention is:

Chinese herbal medicine of the present invention can kill the abnormal common pathogen of pathogen leucorrhea fast, and does not destroy the original pH value of intravaginal, and do not kill the original probiotics of intravaginal, can promote that leucorrhea progressively recovers normal, life-time service can not produce toxic and side effects.

Detailed description of the invention

Further illustrate the present invention below in conjunction with specific embodiment, but the present invention is not limited only to following examples.

Embodiment 1

A kind of external used medicine for the treatment of pathogenic infection leucorrhea exception, by weight, each component of composition is: Herba Artemisiae Annuae 18 parts, 30 parts, Radix Glycyrrhizae, Radix Notoginseng 18 parts, Herba Artemisiae Scopariae 30 parts, Radix Scutellariae 18 parts, Fructus Crataegi 30 parts, Fructus Rosae Laevigatae 18 parts, Radix Gentianae 30 parts, Semen Euryales 6 parts, Semen Ginkgo 20 parts, Semen Plantaginis 6 parts, Radix Paeoniae 20 parts, Rhizoma Cyperi 6 parts, Semen Torreyae 20 parts, Bud of hairyvein agrimony 6 parts, Rhizoma Polygoni Cuspidati 20 parts, Radix Sanguisorbae 6 parts, Folium Hibisci Mutabilis 20 parts, Herba Aristolochiae 6 parts.

Take above each raw material by proportional quantity, decoct with water 3 times, add 8 times of water gagings the 1st time, decoct 2 hours, add 6 times of water gagings 2nd time, decoct 1.5 hours, add 4 times of water gagings the 3rd time, decoct 0.5 hour, collecting decoction, filters, and filtrate is concentrated into the solution that relative density is 1.85 (surveying when 60 DEG C), be filled in spray bottle, obtain spray.

Embodiment 2

A kind of external used medicine for the treatment of pathogenic infection leucorrhea exception, by weight, each component of composition is: Herba Artemisiae Annuae 30 parts, 18 parts, Radix Glycyrrhizae, Radix Notoginseng 30 parts, Herba Artemisiae Scopariae 18 parts, Radix Scutellariae 30 parts, Fructus Crataegi 18 parts, Fructus Rosae Laevigatae 30 parts, Radix Gentianae 18 parts, Semen Euryales 20 parts, Semen Ginkgo 6 parts, Semen Plantaginis 20 parts, Radix Paeoniae 6 parts, Rhizoma Cyperi 20 parts, Semen Torreyae 6 parts, Bud of hairyvein agrimony 20 parts, Rhizoma Polygoni Cuspidati 6 parts, Radix Sanguisorbae 20 parts, Folium Hibisci Mutabilis 6 parts, Herba Aristolochiae 20 parts.

Above each raw material is taken by proportional quantity, decoct with water 3 times, add 5 times of water gagings the 1st time, decoct 2 hours, add 4 times of water gagings 2nd time, decoct 1.5 hours, add 2 times of water gagings the 3rd time, decoct 0.5 hour, collecting decoction, filter, filtrate is concentrated into the extractum that relative density is 1.35 (surveying when 35 DEG C), obtains lotion.

Embodiment 3

A kind of external used medicine for the treatment of pathogenic infection leucorrhea exception, by weight, each component of composition is: Herba Artemisiae Annuae 22 parts, 28 parts, Radix Glycyrrhizae, Radix Notoginseng 22 parts, Herba Artemisiae Scopariae 28 parts, Radix Scutellariae 22 parts, Fructus Crataegi 28 parts, Fructus Rosae Laevigatae 22 parts, Radix Gentianae 28 parts, Semen Euryales 8 parts, Semen Ginkgo 15 parts, Semen Plantaginis 8 parts, Radix Paeoniae 15 parts, Rhizoma Cyperi 8 parts, Semen Torreyae 15 parts, Bud of hairyvein agrimony 8 parts, Rhizoma Polygoni Cuspidati 15 parts, Radix Sanguisorbae 8 parts, Folium Hibisci Mutabilis 15 parts, Herba Aristolochiae 8 parts.

Take above each raw material by proportional quantity, decoct with water 3 times, add 7 times of water gagings the 1st time, decoct 2.5 hours, add 4 times of water gagings 2nd time, decoct 1.5 hours, add 3 times of water gagings the 3rd time, decoct 1 hour, collecting decoction, filters, and filtrate is concentrated into the extractum that relative density is 1.55 (surveying when 65 DEG C), add the cocoa butter of conventional amount used, obtained suppository.

Embodiment 4

A kind of external used medicine for the treatment of pathogenic infection leucorrhea exception, by weight, each component of composition is: Herba Artemisiae Annuae 28 parts, 22 parts, Radix Glycyrrhizae, Radix Notoginseng 28 parts, Herba Artemisiae Scopariae 22 parts, Radix Scutellariae 28 parts, Fructus Crataegi 22 parts, Fructus Rosae Laevigatae 28 parts, Radix Gentianae 22 parts, Semen Euryales 15 parts, Semen Ginkgo 8 parts, Semen Plantaginis 15 parts, Radix Paeoniae 8 parts, Rhizoma Cyperi 15 parts, Semen Torreyae 8 parts, Bud of hairyvein agrimony 15 parts, Rhizoma Polygoni Cuspidati 8 parts, Radix Sanguisorbae 15 parts, Folium Hibisci Mutabilis 8 parts, Herba Aristolochiae 15 parts.

Take above each raw material by proportional quantity, decoct with water 3 times, add 10 times of water gagings the 1st time, decoct 2 hours, add 8 times of water gagings 2nd time, decoct 1.5 hours, add 5 times of water gagings the 3rd time, decoct 0.5 hour, collecting decoction, filters, and filtrate is concentrated into the thick paste that relative density is 1.65 (surveying when 60 DEG C), add the propylene glycol stearate of conventional amount used, obtained suppository.

Embodiment 5

A kind of external used medicine for the treatment of pathogenic infection leucorrhea exception, by weight, each component of composition is: Herba Artemisiae Annuae 25 parts, 25 parts, Radix Glycyrrhizae, Radix Notoginseng 25 parts, Herba Artemisiae Scopariae 25 parts, Radix Scutellariae 25 parts, Fructus Crataegi 25 parts, Fructus Rosae Laevigatae 25 parts, Radix Gentianae 25 parts, Semen Euryales 10 parts, Semen Ginkgo 10 parts, Semen Plantaginis 10 parts, Radix Paeoniae 10 parts, Rhizoma Cyperi 10 parts, Semen Torreyae 10 parts, Bud of hairyvein agrimony 10 parts, Rhizoma Polygoni Cuspidati 10 parts, Radix Sanguisorbae 10 parts, Folium Hibisci Mutabilis 10 parts, Herba Aristolochiae 10 parts.

Take above each raw material by proportional quantity, decoct with water 3 times, add 3 times of water gagings the 1st time, decoct 2 hours, add 2 times of water gagings 2nd time, decoct 1.5 hours, add 1 times of water gaging the 3rd time, decoct 0.5 hour, collecting decoction, filter, it is 1.85 solution that filtrate is concentrated into relative density, be filled in spray bottle, obtain spray.

Experimental example: Chinese herbal medicine of the present invention is to the clinical efficacy of blister type beriberi

Experiment material: external used medicine prepared by the embodiment of the present invention 5.

Experiment place: Qinzhou healthcare hospital for women & children.

1, case and method

2010-2013, connects and controls patient 180 example, wherein abnormal 55 examples of gonococcus leucorrhea, abnormal 60 examples of tulase leucorrhea, mycotic leucorrhea abnormal 65 example.

Usage and dosage: the medicine that the embodiment of the present invention 4 is obtained, every day 3 times, get at every turn and fill in intravaginal in right amount, take out after filling in 30min at every turn, 12d is a course for the treatment of, and this experimental therapy time is 1 course for the treatment of.

2, efficacy determination

Be as the criterion according to clinical symptom disappearance, be divided into recovery from illness, effective, effective, invalid.

Recovery from illness: leucorrhea is white, clear, and amount is normal, and without mutation, free from extraneous odour, without attendant symptoms.

Effective: leucorrhea amount reduces, and abnormal flavour alleviates, and attendant symptoms obviously alleviates.

Invalid: symptom is with treating front no significant difference.

3, curative effect is summed up

	Recovery from illness	Effective	Invalid	Effective percentage
					After the course for the treatment of	85	12	3	97％

This therapeutic process, have no adverse reaction appearance, inner recurrence in a year after drug withdrawal.Be not difficult to find out from this experiment, Chinese herbal medicine of the present invention has significant curative effect to pathogenic infection leucorrhea is abnormal.

Claims

1. treat the external used medicine of pathogenic infection leucorrhea exception for one kind, it is characterized in that, be made up of the raw material of following weight portion: Herba Artemisiae Annuae 18 ~ 30 parts, 18 ~ 30 parts, Radix Glycyrrhizae, Radix Notoginseng 18 ~ 30 parts, Herba Artemisiae Scopariae 18 ~ 30 parts, Radix Scutellariae 18 ~ 30 parts, Fructus Crataegi 18 ~ 30 parts, Fructus Rosae Laevigatae 18 ~ 30 parts, Radix Gentianae 18 ~ 30 parts, Semen Euryales 6 ~ 20 parts, Semen Ginkgo 6 ~ 20 parts, Semen Plantaginis 6 ~ 20 parts, Radix Paeoniae 6 ~ 20 parts, Rhizoma Cyperi 6 ~ 20 parts, Semen Torreyae 6 ~ 20 parts, Bud of hairyvein agrimony 6 ~ 20 parts, Rhizoma Polygoni Cuspidati 6 ~ 20 parts, Radix Sanguisorbae 6 ~ 20 parts, Folium Hibisci Mutabilis 6 ~ 20 parts, Herba Aristolochiae 6 ~ 20 parts.

2. the external used medicine for the treatment of pathogenic infection leucorrhea exception according to claim 1, it is characterized in that, be made up of the raw material of following weight portion: Herba Artemisiae Annuae 22 ~ 28 parts, 22 ~ 28 parts, Radix Glycyrrhizae, Radix Notoginseng 22 ~ 28 parts, Herba Artemisiae Scopariae 22 ~ 28 parts, Radix Scutellariae 22 ~ 28 parts, Fructus Crataegi 22 ~ 28 parts, Fructus Rosae Laevigatae 22 ~ 28 parts, Radix Gentianae 22 ~ 28 parts, Semen Euryales 8 ~ 15 parts, Semen Ginkgo 8 ~ 15 parts, Semen Plantaginis 8 ~ 15 parts, Radix Paeoniae 8 ~ 15 parts, Rhizoma Cyperi 8 ~ 15 parts, Semen Torreyae 8 ~ 15 parts, Bud of hairyvein agrimony 8 ~ 15 parts, Rhizoma Polygoni Cuspidati 8 ~ 15 parts, Radix Sanguisorbae 8 ~ 15 parts, Folium Hibisci Mutabilis 8 ~ 15 parts, Herba Aristolochiae 8 ~ 15 parts.

3. the external used medicine for the treatment of pathogenic infection leucorrhea exception according to claim 1, it is characterized in that, be made up of the raw material of following weight portion: Herba Artemisiae Annuae 25 parts, 25 parts, Radix Glycyrrhizae, Radix Notoginseng 25 parts, Herba Artemisiae Scopariae 25 parts, Radix Scutellariae 25 parts, Fructus Crataegi 25 parts, Fructus Rosae Laevigatae 25 parts, Radix Gentianae 25 parts, Semen Euryales 10 parts, Semen Ginkgo 10 parts, Semen Plantaginis 10 parts, Radix Paeoniae 10 parts, Rhizoma Cyperi 10 parts, Semen Torreyae 10 parts, Bud of hairyvein agrimony 10 parts, Rhizoma Polygoni Cuspidati 10 parts, Radix Sanguisorbae 10 parts, Folium Hibisci Mutabilis 10 parts, Herba Aristolochiae 10 parts.