CN105663429A

CN105663429A - Medicine for treating vesicular beriberi

Info

Publication number: CN105663429A
Application number: CN201610088087.1A
Authority: CN
Inventors: 蒋玉群
Original assignee: Individual
Current assignee: Individual
Priority date: 2016-02-17
Filing date: 2016-02-17
Publication date: 2016-06-15

Abstract

The invention discloses a medicine for treating vesicular beriberi. The medicine is prepared from, by weight, 7-18 parts of sweet wormwood herb, 7-18 parts of licorice roots, 7-18 parts of panax notoginseng, 7-18 parts of herba artemisiae scopariae, 7-18 parts of radix scutellariae, 7-18 parts of hawthorn fruits, 7-18 parts of indigo naturalis, 7-18 parts of Indian trum etflower seeds, 16-36 parts of cranchet ground cherry calyx and fruits, 16-36 parts of herba rabdosiae rubescentis, 16-36 parts of common andrographis herb, 16-36 parts of delavay pararuellia herb, 16-36 parts of buckwheat, 16-36 parts of sargentg loryvine stems, 16-36 parts of roots or bark or leaves of clematis fasciculiflora Franch. and 16-36 parts of fimbriatestipulate begonia herb. The Chinese herb medicine can quickly kill pathogenic bacteria, fungi and viruses of vesicular beriberi, can quickly diminish blisters caused by beriberi remove blister liquid, prevent infection and thoroughly cure vesicular beriberi, and does not cause skin irritation when used for a long time.

Description

A kind of medicine treating blister type beriberi

Technical field

The present invention relates to a kind of medicine, be specifically related to a kind of medicine treating blister type beriberi.

Background technology

Beriberi is the popular name of tinea pedis, also referred to as " tinea pedis ", is a kind of extremely common fungal infection dermatoses. In adult, the people of 70-80% suffers from beriberi, and simply weight is different. Beriberi is everlasting and is increased the weight of summer, and winter alleviates, and also has people not heal all the year round. Medically generally beriberi is divided three types: erosive type, vesicle, squama keratinization type beriberi. Beriberi is caused by dermatophytosis such as fungus, candidiasis, mycete etc., and dermatophytosis infects usually through the publilc baths polluted, the floor of edge of pool, bath towel, public slippers, foot basin. Foot hyperhidrosis, humidity or footgear stuffiness etc. all can bring out primary disease. And beriberi and foot hyperhidrosis, foot odor are usually accompanied. When hyperhidrosis, antibacterial amount reproduction on foot also decomposes keratoprotein, adds the carbamide in perspiration, lactic acid, produces foot odor.

Blister type beriberi is often acute period of expansion beriberi, and onset is relatively anxious, and Xia Chongdong is light. Primary lesion is based on phlysis, and in groups or distribute, wall thickness, bleb liquid is clear, is frequently located between toe, the foot heart and foot lateral margin. Vesicle is positioned under horny layer of epidermis, and owing to foot sole of the foot portion horny layer is thicker, vesicle wall is not easily the worse for wear, and surrounding skin is without blush. If not secondary bacterial infection, after a couple of days, bleb liquid can absorbed themselves. Forming ring-type desquamation after ruptured blister, skin lesion continues to expand to surrounding. Skin lesion constantly extends to surrounding when spreading, and part phlysis can be fused into big vesicle. If secondary bacterial infection, then there is blush in bleb week, and bleb liquefaction pus becomes cloudy. After bleb wall diabrosis, there is rotten to the corn or swelling in local. Now, if inappropriate medication inflammation can not get timely control, then easily caused by some complication such as lymphangitises.

At present, market there is no the Chinese herbal medicine being specifically designed for blister type beriberi, the unguentum of existing the medicine such as daktarin, zinci undecylenatis compositum of the treatment beriberi that market exists, the refreshing powder of foot etc, liniment, spray product, specific aim is not strong, the effect for the treatment of beriberi is poor, easily recurs after drug withdrawal.

Summary of the invention

For above deficiency, the present invention provides a kind of medicine treating blister type beriberi, and it overcomes the weak point of traditional treatment beriberi, and blister type beriberi is had significant curative effect, and it has short treating period, instant effect, the advantage that do not recur.

For solving the problems referred to above, the present invention is achieved through the following technical solutions:

A kind of medicine treating blister type beriberi, is made up of the raw material of following weight portion: Herba Artemisiae Annuae 7～18 parts, 7～18 parts of Radix Glycyrrhizae, Radix Notoginseng 7～18 parts, Herba Artemisiae Scopariae 7～18 parts, Radix Scutellariae 7～18 parts, Fructus Crataegi 7～18 parts, Indigo Naturalis 7～18 parts, Semen Oroxyli 7～18 parts, Calyx Seu Fructus Physalis 16～36 parts, Rabdosia rubescens 16～36 parts, Herba Andrographis 16～36 parts, Herb Pararuelliae delavayanae 16～36 parts, 16～36 parts of Semen Fagopyri Esculenti, Caulis Sargentodoxae 16～36 parts, little viscous medicine 16～36 parts, Rhizoma Begoniae Fimbristipulatae 16～36 parts.

Preferably, the medicine of described treatment blister type beriberi is made up of the raw material of following weight portion: Herba Artemisiae Annuae 9～15 parts, 9～15 parts of Radix Glycyrrhizae, Radix Notoginseng 9～15 parts, Herba Artemisiae Scopariae 9～15 parts, Radix Scutellariae 9～15 parts, Fructus Crataegi 9～15 parts, Indigo Naturalis 9～15 parts, Semen Oroxyli 9～15 parts, Calyx Seu Fructus Physalis 20～35 parts, Rabdosia rubescens 20～35 parts, Herba Andrographis 20～35 parts, Herb Pararuelliae delavayanae 20～35 parts, 20～35 parts of Semen Fagopyri Esculenti, Caulis Sargentodoxae 20～35 parts, little viscous medicine 20～35 parts, Rhizoma Begoniae Fimbristipulatae 20～35 parts.

It is highly preferred that the medicine for the treatment of blister type beriberi is made up of the raw material of following weight portion: Herba Artemisiae Annuae 12 parts, 12 parts of Radix Glycyrrhizae, Radix Notoginseng 12 parts, Herba Artemisiae Scopariae 12 parts, Radix Scutellariae 12 parts, Fructus Crataegi 12 parts, Indigo Naturalis 12 parts, Semen Oroxyli 12 parts, Calyx Seu Fructus Physalis 30 parts, Rabdosia rubescens 30 parts, Herba Andrographis 30 parts, Herb Pararuelliae delavayanae 30 parts, 30 parts of Semen Fagopyri Esculenti, Caulis Sargentodoxae 30 parts, little viscous medicine 30 parts, Rhizoma Begoniae Fimbristipulatae 30 parts.

The dosage form of Chinese herbal medicine of the present invention can be the medically acceptable dosage forms such as solution, lotion, tincture, cream, ointment, plaster, and their preparation method, supplementary product consumption are undertaken by existing common process.

The drug effect principle of each component of the present invention is as follows:

Herba Artemisiae Annuae, for the dry aerial parts of feverfew Herba Artemisiae Annuae ArtemisiaannuaL.. Bud stage is gathered, and extracts aerial parts, chopping, dries. Ancient name " " (q ì n). Clearing away summer-heat, except steaming, preventing the attack (or recurrence) of malaria. Generate heat for pathogenic summer-heat, fever due to yin deficiency, night fever abating at dawn, hectic fever due to YIN-deficiency consumptive fever, malaria cold and heat, jaundice due to damp-heat. It it is a kind of cheap antimalarial drug.

Radix Glycyrrhizae, (formal name used at school: GlycyrrhizauralensisFisch) calls: state is old, Herba Hedyotis cantonensis, Glycyrrhiza uralensis Fisch., sweet root. Pulse family, Glycyrrhiza perennial herb, root is sturdy with root stock, is a kind of tonification Chinese herbal medicine. To human body well a kind of medicine, medicinal part is root and rhizome. Radix Glycyrrhizae contains multiple chemical composition, and main component has glycyrrhizic acid, liquiritin etc. The chemical composition of Radix Glycyrrhizae is extremely complex, and from Radix Glycyrrhizae, isolated compound has the tens of kinds of compounds such as glycyrrhizin, enoxolone, liquiritin, isoliquiritin, neoliquriitin, neoisoliquiritin, glycyrrhizin, isoliquiritigenin and licoricidin (+)-Licoricidin., glycyrol, isoglycyrol, 7-methylcoumarin essence, umbelliferone so far. Effect: 1, for insufficiency of heart-QI, severe palpitation, irregularly intermittent and regularly intermittent pulse, and deficiency of spleen-QI and stomach-QI, fatigue and weakness etc. The former, normal and Ramulus Cinnamomi compatibility, such as Ramuli Cinnamomi and Glycyrrhizae Decoction, zhigancao decoction. The latter, is often equal to use with Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, ball etc. in decoction of four noble drugs, reason. 2, for ulcer sores, laryngopharynx swelling and pain etc. Can be alone, for oral administration or external application, or compatibility application. Ulcer sores, is often equal to use with Flos Lonicerae, Fructus Forsythiae, plays the merit of heat-clearing and toxic substances removing altogether, such as Xian fang Huoming Yin. Laryngopharynx swelling and pain, the normal and same use of Radix Platycodonis, such as Radix Platycodonis decoction. If pesticide, alimentary toxicosis, often join Semen phaseoli radiati or be decocted in water for oral dose with Radix Saposhnikoviae. 3, for asthma and cough.Can be alone, also can the application of compatibility other drug. As controlled the ERCHEN TANG of cough due to damp-phlegm; Control the Linggan Wuwei Jiangxin Tang of cold-phlegm cough with asthma; Control the sangxing decoction of dry stool phlegm cough; Control pyretic toxicity and cause the Radix Platycodonis decoction of the stench purulent sputum of lung abscess cough and spit; Control the Gancao Ganjiang soup etc. of cough and spit saliva foam. Another cough due to pathogenic wind-heat, cough due to wind and cold, phlegm heat cough also Chang Peiwu applies.

Radix Notoginseng, Chinese medicine name. Dry root and rhizome for panax araliaceae plant Panaxnotoginseng (Burk.) F.H.Chen. Cure mainly: be used for spitting blood, spit blood, epistaxis, have blood in stool, metrorrhagia, traumatic hemorrhage, chest and abdomen twinge, tumbling and swelling.

Herba Artemisiae Scopariae, another name Adeps Bovis seu Bubali, Tian Naili, because of dirt, Ma Xian, capillary wormwood, floss Artemisia, Herba Artemisiae Sieversianae, spire Herba Artemisiae Annuae, An Lvcao, Latin literary fame ArtemisiacapillarisThunb. tubular flower order, Compositae, origanum Artemisia are dead through the winter, old of Chun Zeyin and give birth to, therefore named because of old or Herba Artemisiae Scopariae. Artemisia is then become to its Seedling of summer, therefore also known as Herba Artemisiae Scopariae. Herba Artemisiae Scopariae clearing away heat-damp and promoting diuresis; Jaundice eliminating. Cure mainly: jaundice, dysuria, eczema pruritus, infectious jaundice type hepatitis. Pharmaceutical research has function of gallbladder promoting, liver function protecting, and antipyretic, antiinflammatory, blood fat reducing, blood pressure lowering, coronary dilating etc. acts on.

Radix Scutellariae (Classification system: ScutellariabaicalensisGeorgi), calls Radix Scutellariae, tsuchikane tea root, is Labiatae Scutellaria herbaceos perennial. The root of Radix Scutellariae is used as medicine, bitter in the mouth, cold in nature, has heat clearing and damp drying, eliminating fire and detoxication, hemostasis, the effect such as antiabortive. Pharmacological action: 1, antibacterial action: Radix Scutellariae decoct 100% concentration, flat band method is tested, dysentery bacterium, Bacillus typhi, Salmonella paratyphi, vibrio cholera, escherichia coli, Bacillus proteus, bacillus pyocyaneus, staphylococcus, hemolytic vessel used to hold grain at the imperial sacrifice coccus (a, B), Diplococcus pneumoniae, diphtheria corynebacterium etc. there is inhibitory action. Radix Scutellariae decoct test tube method test 1:1280 concentration can suppress Bacillus typhi, Hemolytic streptococcus a, 1:640 control of the concentration Hemolytic streptococcus B, Diplococcus pneumoniae and shigella flexneri, bacillus tuberculosis typus humanus's H37,1:320 concentration can suppress vibrio cholera, dysentery bacterium; During 1:80 concentration, sonne bacillus has inhibitory action. Radix Scutellariae alcohol immersion 0.5g/ml or 0.05g/ml, cultivates with agar slant, and medicinal liquid mixes with culture medium 1:1, and bacillus pyocyaneus is had inhibitory action. Radix Scutellariae alcohol immersion 2g/ml concentration, escherichia coli, Fructus Citri tangerinae grass bacillus, staphylococcus aureus are had inhibitory action by Plating test. Radix Scutellariae decoct, alcohol extraction agent 1g/ml concentration, all have the effect of pressing down by flat band method to meningococcus when testing. 2, antifungic action: Radix Scutellariae decocting liquid, test tube slant method tests 4% control of the concentration Canis familiaris L. denticle born of the same parents bacterium and trichophyton, 8% control of the concentration oidium schoenleinii, the mutation of 10% control of the concentration oidium schoenleinii Mongolia, 15% control of the concentration homocentricity trichophyton and rust trichophyton. Radix Scutellariae water logging agent 1:3 concentration is in vitro to trichophyton, Trichophyton concentricunm, and oidium schoenleinii, Microsporon audouini, Pilus Caprae seu Ovis sample microspore tinea bacterium, epidermophyton rubrum, K, W, family name epidermophyton, star nocardia etc. have bacteriostasis in various degree. 3, antivirus action: Radix Scutellariae decoct 25-100% concentration, hepatitis B virus DNA is replicated with inhibitory action by vitro tests. [5]

Fructus Crataegi (CrataeguspinnatifidaBunge), has another name called fruit, Fructus Pyri Pashiae in mountain, Rosaceae Crataegus, stone fruit, and caryoplasm is hard, and sarcocarp is thin, and taste is micro-sour and astringent.Fruit is raw-eaten or makes preserved fruit fruitcake, can be used as medicine after drying, it is Chinese distinctive medicine fruit dual-purpose seeds, there is the effects such as blood fat reducing, blood pressure, heart tonifying, arrhythmia, also being simultaneously the good medicine of spleen benefiting and stimulating the appetite, relieving dyspepsia, phlegm reduction of blood circulation promoting, the disease such as chest and diaphragm spleen is full, hernia, blood stasis, amenorrhea has good curative effect. Flavone compound vitexin in Fructus Crataegi, is the medicine that a kind of antitumaous effect is stronger, and the internal growth of cancer cells of suppression, propagation and infiltration metastasis are all had certain effect by its extract.

Indigo Naturalis, Chinese medicine name. For rank of nobility dinner party section plant Acanthaceous indigo, polygonaceae plant polygonum tinctorium ait., the leaf of cruciferae isatis or the processed prepared dried powder of stem and leaf, agglomerate or granule. Tool heat-clearing and toxic substances removing, blood cooling and ecchymoses removing, pathogenic fire purging arresting convulsion etc. acts on, and is also commonly used for printing and dyeing cloth, thrush etc. in ancient times. Main product in Fujian, Yunnan, the ground such as Jiangsu. Nature and flavor are salty-cold, have the effects such as heat-clearing and toxic substances removing, blood cooling and ecchymoses removing, pathogenic fire purging arresting convulsion. It is mainly used in epidemic febrile disease intenseness of heat, macule, spits blood, spits blood, pharyngalgia aphtha, and pediatric epilepsy scared, skin ulcer swells, erysipelas, snake bite and insect sting etc.

Semen Oroxyli (Oroxylumindicum), belongs to Bignoniaceae. Seed, peel of stem, containing baicaligenin, have antiinflammatory, antiallergic action, diuresis, function of gallbladder promoting, the effect of cholesterol reducing.

Calyx Seu Fructus Physalis, has another name called: mountain Miss; Calyx Seu Fructus Physalis, is main product ground in Hebei Bashang Region. Calyx Seu Fructus Physalis is Solanaceae perennial herb, medicinal peel, has the function of heat-clearing and toxic substances removing, antitussive diuresis.

Rabdosia rubescens has another name called Rabdosia rubescens, belongs to perennial herb or undershrub, undershrub for Labiatae scented tea, is that Labiatae Rabdosia plant is cracked rice fork mutation, gains the name because its plant condenses butterfly-shaped ice slush sheet as thin as cicada's wings, that come in every shape. The full silvery white Borneolum Syntheticum of Herb knot. There is anti-inflammatory analgetic, effect that stomach invigorating is invigorated blood circulation. Recording according to " modern Chinese medicine voluminous dictionary ", the nature and flavor of Rabdosia rubescens and function be: bitter, sweet, be slightly cold, and heat clearing away, removing toxic substances, promoting blood circulation and stopping pain, for laryngopharynx swelling and pain, tonsillitis, snake bite and insect sting, rheumatic ostalgia etc. Main Function has: the effects such as antitumor, antibacterial action reconciliation heat drop is dry. Research find Rabdosia rubescens also have antipyretic, drop dry wet one's whistle, blood fat reducing, the effect such as blood pressure lowering. Cold, fever, aphtha of the mouth and tongue, burnt heat being got angry etc. has good preventive and therapeutic action. As middle-aged and elderly people and some special populations, such as daily health caring beverages such as teacher, performer, announcers, and can there is effect of slow down aging.

Herba Andrographis (formal name used at school: Andrographispaniculata (Burm.f.) Nees), has another name called Chun Lianqiuliu, Herba Andrographitis, Lan Helian, Radix Gentianae, gold Rhizoma et radix valerianae, Tremella aurantialba Bandoni et Zang hook, India's grass, Herba vallisneriae Spiralis etc. Having an antiinflammatory action, adopt dimethylbenzene, acetic acid induced mice skin or abdominal cavity capillary permeability to increase, gavage deoxyandrographolide or dehydrorographolide all can reduce oozing out of capillary wall, and compare P < 0.05 or P < 0.01. Hemorrhagic necrotic caused by rat Oleum Tiglii is oozed out, and deoxyandrographolide has obvious inhibitory action. Leukoplania in rat CMC capsule is had obvious inhibitory action in 7.5 hours under the heavy dose of 100mg/ capsule by deoxyandrographolide, andrographolide and neoandrographolide. Experiment it was additionally observed that Adrenal Cortex function is had excitation in various degree by these four andrographolide, with dehydrorographolide for the strongest. Andrographolide and neoandrographolide have the colibacillary effect of suppression.

Herb Pararuelliae delavayanae, perennial herb, effect: 1. " Yunnan Chinese herbal medicine ": " heat-clearing and toxic substances removing, reducing swelling and alleviating pain.Control fracture, tuberculous lymphadenitis, parotitis, traumatic hemorrhage. " 2. " choosing of Yunnan Chinese herbal medicine ": " antiinflammatory is drawn out pus by applying a plaster to the affected part, granulation promoting, dissipating blood stasis tissue regeneration promoting, parasite killing. Control acute suppurative tonsillitis, pneumonia, sore abscess, the raw maggot of wound infection. " 3. " catalogue planted by Guizhou medicine ": " controls impairment caused by overstrain, delivers ". Cure mainly: heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling. Control pneumonia, tonsillitis, parotitis, scrofula, abscess sore, fracture, traumatic infection.

Semen Fagopyri Esculenti (formal name used at school: FagopyrumesculentumMoench.), another name: sweet buckwheat, Wu Mai, triangle wheat etc.; Annual herb. Semen Fagopyri Esculenti sugariness is cool, has the wide intestinal of appetizing, therapeutic method to keep the adverse QI flowing downwards removing food stagnancy. Controlling dry cholera, the intestines and stomach stagnates, effect of chronic diarrhea.

Caulis Sargentodoxae (Classification system: Sargentodoxacuneata (Oliv.) Rehd.etWils.), practises and claims Caulis Sargentodoxae, have another name called Caulis seu Radix Schisandrae Henryi, Folium Styracis Suberifoliae rattan etc., and Caulis Sargentodoxae is fallen leaves, bejuco; There is heat-clearing and toxic substances removing, promoting blood circulation to remove obstruction in the collateral, the effect expellingged wind and relieving convulsion. Rheumatic arthralgia, bloody dysentery, stranguria with blood, menoxenia, infantile malnutrition, worm pain, injury from falling down.

Little viscous medicine, another name three-jaw gold dragon, SANYE Caulis Kadsurae Longipedunculatae, effect: promoting the circulation of QI to relieve pain medicine; Drug for invigorating blood circulation and eliminating stasis; Medicine for the treatment of rheumatism and arthritis. Cure mainly: stagnation of QI abdominal distention; Rheumatic ostalgia; Traumatic injury; Acute mastitis; Furuncle toxic swelling; Knife injury is hemorrhage.

Rhizoma Begoniae Fimbristipulatae (formal name used at school: Begoniafimbristipula) has another name called Radix Semiaquilegiae, red autumnal leaves, scattered blood, dragon and tiger leaf, night crosses water certain herbaceous plants with big flowers red, red, is a kind of Chinese crude drug. Bulb or Herb for Begoniaceae plant Radix Semiaquilegiae. Function cures mainly clearing away heat and cooling blood, promoting blood circulation and detoxication. Control summer-heat hyperpyrexia, cough due to lung-heat, spitting of blood, osteopatia sprain, blood stasis pain, sore scabies, burn due to hot liquid or fire.

The invention have the benefit that

Chinese herbal medicine of the present invention can quickly kill the malignant bacteria of blister type beriberi, fungus and virus, stops beriberi blister to expand to surrounding, can dispel bleb liquid, it is prevented that infects, and thoroughly cures blister type beriberi, and life-time service output will not stimulate skin phenomena.

Detailed description of the invention

Further illustrate the present invention below in conjunction with specific embodiment, but the present invention is not limited only to following example.

Embodiment 1

A kind of medicine treating blister type beriberi, by weight, each component of composition is: Herba Artemisiae Annuae 7 parts, 18 parts of Radix Glycyrrhizae, Radix Notoginseng 7 parts, Herba Artemisiae Scopariae 18 parts, Radix Scutellariae 7 parts, Fructus Crataegi 18 parts, Indigo Naturalis 7 parts, Semen Oroxyli 18 parts, Calyx Seu Fructus Physalis 16 parts, Rabdosia rubescens 36 parts, Herba Andrographis 16 parts, Herb Pararuelliae delavayanae 36 parts, 16 parts of Semen Fagopyri Esculenti, Caulis Sargentodoxae 36 parts, little viscous medicine 16 parts, Rhizoma Begoniae Fimbristipulatae 36 parts.

Above each raw material is weighed by proportional quantity, boiling 3 times, adds 8 times amount water for the 1st time, decocts 2 hours, add 6 times amount water 2nd time, decoct 1.5 hours, add 4 times amount water for the 3rd time, decoct 0.5 hour, collecting decoction, filtering, filtrate is concentrated into the solution that relative density is 1.85 (surveying when 60 DEG C), obtained solution agent.

Embodiment 2

A kind of medicine treating blister type beriberi, by weight, the each component of composition is: a kind of Chinese herbal medicine treating erosive beriberi, its component is: Herba Artemisiae Annuae 18 parts, 7 parts of Radix Glycyrrhizae, Radix Notoginseng 18 parts, Herba Artemisiae Scopariae 7 parts, Radix Scutellariae 18 parts, Fructus Crataegi 7 parts, Indigo Naturalis 18 parts, Semen Oroxyli 7 parts, Calyx Seu Fructus Physalis 36 parts, Rabdosia rubescens 16 parts, Herba Andrographis 36 parts, Herb Pararuelliae delavayanae 16 parts, 36 parts of Semen Fagopyri Esculenti, Caulis Sargentodoxae 16 parts, little viscous medicine 36 parts, Rhizoma Begoniae Fimbristipulatae 16 parts.

Above each raw material is weighed by proportional quantity, boiling 3 times, adds 6 times amount water for the 1st time, decocts 2 hours, add 4 times amount water 2nd time, decoct 1.5 hours, add 2 times amount water for the 3rd time, decoct 0.5 hour, collecting decoction, filtering, filtrate is concentrated into the extractum that relative density is 1.25 (surveying when 70 DEG C), obtains lotion.

Embodiment 3

A kind of medicine treating blister type beriberi, by weight, each component of composition is: Herba Artemisiae Annuae 9 parts, 15 parts of Radix Glycyrrhizae, Radix Notoginseng 9 parts, Herba Artemisiae Scopariae 15 parts, Radix Scutellariae 9 parts, Fructus Crataegi 15 parts, Indigo Naturalis 9 parts, Semen Oroxyli 15 parts, Calyx Seu Fructus Physalis 20 parts, Rabdosia rubescens 35 parts, Herba Andrographis 20 parts, Herb Pararuelliae delavayanae 35 parts, 20 parts of Semen Fagopyri Esculenti, Caulis Sargentodoxae 35 parts, little viscous medicine 20 parts, Rhizoma Begoniae Fimbristipulatae 35 parts.

Weigh above each raw material, boiling 3 times by proportional quantity, add 7 times amount water for the 1st time, decoct 2.5 hours, add 4 times amount water for the 2nd time, decoct 1.5 hours, add 3 times amount water for the 3rd time, decoct 1 hour, collecting decoction, filter, obtain tincture.

Embodiment 4

A kind of medicine treating blister type beriberi, by weight, each component of composition is: Herba Artemisiae Annuae 15 parts, 9 parts of Radix Glycyrrhizae, Radix Notoginseng 15 parts, Herba Artemisiae Scopariae 9 parts, Radix Scutellariae 15 parts, Fructus Crataegi 9 parts, Indigo Naturalis 15 parts, Semen Oroxyli 9 parts, Calyx Seu Fructus Physalis 35 parts, Rabdosia rubescens 20 parts, Herba Andrographis 35 parts, Herb Pararuelliae delavayanae 20 parts, 35 parts of Semen Fagopyri Esculenti, Caulis Sargentodoxae 20 parts, little viscous medicine 35 parts, Rhizoma Begoniae Fimbristipulatae 20 parts.

Above each raw material is weighed by proportional quantity, boiling 3 times, adds 10 times amount water for the 1st time, decocts 2 hours, add 8 times amount water 2nd time, decoct 1.5 hours, add 5 times amount water for the 3rd time, decoct 0.5 hour, collecting decoction, filtering, filtrate is concentrated into the thick paste that relative density is 1.65 (surveying when 60 DEG C), adds sorbitol fatty acid methyl ester adjuvant and prepares cream.

Embodiment 5

A kind of medicine treating blister type beriberi, by weight, each component of composition is: Herba Artemisiae Annuae 12 parts, 12 parts of Radix Glycyrrhizae, Radix Notoginseng 12 parts, Herba Artemisiae Scopariae 12 parts, Radix Scutellariae 12 parts, Fructus Crataegi 12 parts, Indigo Naturalis 12 parts, Semen Oroxyli 12 parts, Calyx Seu Fructus Physalis 30 parts, Rabdosia rubescens 30 parts, Herba Andrographis 30 parts, Herb Pararuelliae delavayanae 30 parts, 30 parts of Semen Fagopyri Esculenti, Caulis Sargentodoxae 30 parts, little viscous medicine 30 parts, Rhizoma Begoniae Fimbristipulatae 30 parts.

Above each raw material is weighed by proportional quantity, boiling 3 times, adds 3 times amount water for the 1st time, decocts 2 hours, add 2 times amount water 2nd time, decoct 1.5 hours, add 1 times amount water for the 3rd time, decoct 0.5 hour, collecting decoction, filtering, filtrate is concentrated into the thick paste that relative density is 1.85 (surveying when 60 DEG C), adds vaseline and prepares ointment.

Experimental example: the Chinese herbal medicine of the present invention clinical efficacy to blister type beriberi

Experiment material: the medicine that the embodiment of the present invention 4 prepares.

Experiment place: Qinzhou healthcare hospital for women & children.

1, case and method

2010-2013, connects and controls patient 185 example, male 95 example, women 90 example, and the age is in 12-70 year. Symptom: foot edge, foot bottom are the phlysis that wall thickness is full, and there is bulla local, and bleb liquid is transparent, and around without blush, pruritus is hard to bear.

Usage and dosage: the Chinese herbal medicine of the embodiment of the present invention 4 preparation, every day 3 times, takes appropriate cream every time and is applied to affected part, and 7d is a course for the treatment of, and this experimental therapy time is 1 course for the treatment of.

2, efficacy determination

It is as the criterion according to clinical symptom disappearance, is divided into recovery from illness, effective, effective, invalid.

Recovery from illness: Clinical symptom and sign disappears, foot edge, foot bottom blister are wholly absent, and the complete shape of pruritus disappears.

Effective: Clinical symptom and sign substantially or mostly disappears, foot edge, foot bottom blister disappear substantially, and the blister that minority not exclusively disappears sharply diminishes, shrivelled, occurs foot pruritis once in a while.

Invalid: Clinical symptom and sign is without improvement, and foot pruritus is without substantially alleviating situation, and foot edge, foot bottom blister are substantially without significant change, and pruritis is lasting.

3, curative effect is summed up

	Recovery from illness	Effective	Invalid	Effective percentage
					After one course for the treatment of	85	12	3	97%

This therapeutic process, have no adverse reaction appearance, internal recurrence in a year after drug withdrawal. Being not difficult to find out from this experiment, blister type beriberi is had significant curative effect by Chinese herbal medicine of the present invention.

Claims

1. the medicine treating blister type beriberi, it is characterized in that, be made up of the raw material of following weight portion: Herba Artemisiae Annuae 7～18 parts, 7～18 parts of Radix Glycyrrhizae, Radix Notoginseng 7～18 parts, Herba Artemisiae Scopariae 7～18 parts, Radix Scutellariae 7～18 parts, Fructus Crataegi 7～18 parts, Indigo Naturalis 7～18 parts, Semen Oroxyli 7～18 parts, Calyx Seu Fructus Physalis 16～36 parts, Rabdosia rubescens 16～36 parts, Herba Andrographis 16～36 parts, Herb Pararuelliae delavayanae 16～36 parts, 16～36 parts of Semen Fagopyri Esculenti, Caulis Sargentodoxae 16～36 parts, little viscous medicine 16～36 parts, Rhizoma Begoniae Fimbristipulatae 16～36 parts.

2. the medicine for the treatment of blister type beriberi according to claim 1, it is characterized in that, be made up of the raw material of following weight portion: Herba Artemisiae Annuae 9～15 parts, 9～15 parts of Radix Glycyrrhizae, Radix Notoginseng 9～15 parts, Herba Artemisiae Scopariae 9～15 parts, Radix Scutellariae 9～15 parts, Fructus Crataegi 9～15 parts, Indigo Naturalis 9～15 parts, Semen Oroxyli 9～15 parts, Calyx Seu Fructus Physalis 20～35 parts, Rabdosia rubescens 20～35 parts, Herba Andrographis 20～35 parts, Herb Pararuelliae delavayanae 20～35 parts, 20～35 parts of Semen Fagopyri Esculenti, Caulis Sargentodoxae 20～35 parts, little viscous medicine 20～35 parts, Rhizoma Begoniae Fimbristipulatae 20～35 parts.

3. the medicine for the treatment of blister type beriberi according to claim 1, it is characterized in that, be made up of the raw material of following weight portion: Herba Artemisiae Annuae 12 parts, 12 parts of Radix Glycyrrhizae, Radix Notoginseng 12 parts, Herba Artemisiae Scopariae 12 parts, Radix Scutellariae 12 parts, Fructus Crataegi 12 parts, Indigo Naturalis 12 parts, Semen Oroxyli 12 parts, Calyx Seu Fructus Physalis 30 parts, Rabdosia rubescens 30 parts, Herba Andrographis 30 parts, Herb Pararuelliae delavayanae 30 parts, 30 parts of Semen Fagopyri Esculenti, Caulis Sargentodoxae 30 parts, little viscous medicine 30 parts, Rhizoma Begoniae Fimbristipulatae 30 parts.