CN105561203A - Drug for treating comprehensive beriberi - Google Patents
Drug for treating comprehensive beriberi Download PDFInfo
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- CN105561203A CN105561203A CN201610088096.0A CN201610088096A CN105561203A CN 105561203 A CN105561203 A CN 105561203A CN 201610088096 A CN201610088096 A CN 201610088096A CN 105561203 A CN105561203 A CN 105561203A
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- A61K36/88—Liliopsida (monocotyledons)
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Abstract
The invention discloses a drug for treating comprehensive beriberi. The drug is prepared from, by weight, 7-28 parts of cortex pseudolaricis, 7-28 parts of cortex phellodendri, 7-28 parts of tobacco leaf, 7-28 parts of radix curcumae longae, 7-28 parts of garden balsam, 7-28 parts of fruit of cubeb litsea tree, 7-28 parts of wrinkled gianthyssop herb, 7-28 parts of sweet wormwood herb, 18-35 parts of radix lithospermi, 18-35 parts of herba houttuyniae, 18-35 parts of herba artemisiae scopariae, 18-35 parts of folium artemisiae argyi, 18-35 parts of rhizoma atractylodis, 18-35 parts of common carpesium fruit, 18-35 parts of fruit of rangoon creeper, 18-35 parts of cortex dictamni, 18-35 parts of tribulus terrestris, 18-35 parts of periostracum cicada, 18-35 parts of cortex acanthopanacis and 18-35 parts of lesser duckweed. The Chinese herbal medicine has the advantages of being short in treatment course, capable of becoming effective quickly and high in microbicidal efficacy when used for treating comprehensive beriberi, and can shrink pores on the feet, prevent excessive loss of water in the feet, help repair the cuticle on the feet, and promote healing of chapped skin.
Description
Technical field
The present invention relates to a kind of medicine, be specifically related to a kind of medicine for the treatment of comprehensive beriberi.
Background technology
Beriberi is the popular name of tinea pedis, and also claiming " tinea pedis ", is a kind of extremely common fungal infection dermatoses.In adult, the people of 70-80% suffers from beriberi, and just weight is different.Beriberi is everlasting and is increased the weight of summer, and winter alleviates, and also has people not heal all the year round.Medically usually, divide three types by beriberi: erosive type, vesicle, squama keratinization type beriberi.
Erosive beriberi is caused by dermatophytosis (fungus or title mycete).In all beriberi types, erosive beriberi is one the most common, is apt to occur between the 3rd and the four, four and five toe.From the beginning of moist between toe, dipping turns white, and after dry desquamation, peels off rotten to the corn face that scurf is moistening, flushing or with breach, oddly itches, easy secondary infection.
Blister type beriberi is often acute period of expansion beriberi, and onset is comparatively anxious, and Xia Chongdong is light.Primary lesion is based on phlysis, and in groups or distribute, wall thickness, bleb liquid is clear, is often positioned between toe, the sufficient heart and sufficient lateral margin.Under vesicle is positioned at horny layer of epidermis, because sufficient sole of the foot portion horny layer is thicker, vesicle wall is not easily the worse for wear, and surrounding skin is without blush.If not secondary bacterial infection, after a couple of days, bleb liquid can absorbed themselves.Form ring-type desquamation after ruptured blister, skin lesion continues to expand to surrounding.When skin lesion constantly spreads to surrounding expansion, part phlysis can be fused into large vesicle.If secondary bacterial infection, then there is blush in bleb week, and bleb liquefaction pus becomes muddy.After the diabrosis of bleb wall there is rotten to the corn or swelling in local.
Squama keratinization type beriberi is apt to occur in heel, sufficient edge.Show as hyperkeratosis, dry, coarse, desquamation, substrate is light red.Many monopodias occur, and also can all involve by biped.Conscious pruritus is comparatively light, pain of often chapping winter.Because fungal infection causes xerosis cutis, cutin slightly thick, desquamation, easily chap.Squama keratinization type beriberi is without vesicle and suppuration, and the course of disease is slow, and how not healing, Most patients is transformed by erosive type, vesicle throughout the year.
Mutually can transform under certain condition between various types of beriberi, foot also may occur three kinds of dissimilar beriberi simultaneously.At present, market there is no medicine erosive beriberi, blister type beriberi, squama keratinization type beriberi being had to significant curative effect.The existing medicine of the treatment beriberi that market exists, can only the growth of anti-bacteria as the product such as daktarin, zinci undecylenatis compositum, can reach antipruritic effect in a short time, but drug effect is not long, once drug withdrawal, and will recurrent exerbation.
Summary of the invention
For above deficiency, the invention provides a kind of medicine for the treatment of comprehensive beriberi, it all has significant curative effect to erosive beriberi, blister type beriberi, squama keratinization type beriberi, can quick sterilization, antipruritic, recover foot horny layer microcirculation, repairing impaired pedal skin, there is not anaphylaxis in life-time service, does not produce drug resistance.
Treat a medicine for comprehensive beriberi, be made up of the component of following weight portion:
Cortex Pseudolaricis 7 ~ 28 parts, Cortex Phellodendri 7 ~ 28 parts, 7 ~ 28 parts, Nicotiana tabacum L., 7 ~ 28 parts, Rhizoma Curcumae Longae, Flos Impatientis 7 ~ 28 parts, Fructus Litseae 7 ~ 28 parts, Herba Pogostemonis 7 ~ 28 parts, Herba Artemisiae Annuae 7 ~ 28 parts, Radix Arnebiae (Radix Lithospermi) 18 ~ 35 parts, Herba Houttuyniae 18 ~ 35 parts, Herba Artemisiae Scopariae 18 ~ 35 parts, Folium Artemisiae Argyi 18 ~ 35 parts, Rhizoma Atractylodis 18 ~ 35 parts, Fructus Carpesii 18 ~ 35 parts, Fructus Quisqualis 18 ~ 35 parts, Cortex Dictamni 18 ~ 35 parts, Fructus Atriplicis Sibiricae 18 ~ 35 parts, Periostracum Cicadae 18 ~ 35 parts, Cortex Acanthopancis 18 ~ 35 parts, 18 ~ 35 parts, Herba Spirodelae.
Preferably, treat the medicine of comprehensive beriberi, be made up of the component of following weight portion: Cortex Pseudolaricis 12 ~ 20 parts, Cortex Phellodendri 12 ~ 20 parts, 12 ~ 20 parts, Nicotiana tabacum L., 12 ~ 20 parts, Rhizoma Curcumae Longae, Flos Impatientis 12 ~ 20 parts, Fructus Litseae 12 ~ 20 parts, Herba Pogostemonis 12 ~ 20 parts, Herba Artemisiae Annuae 12 ~ 20 parts, Radix Arnebiae (Radix Lithospermi) 22 ~ 32 parts, Herba Houttuyniae 22 ~ 32 parts, Herba Artemisiae Scopariae 22 ~ 32 parts, Folium Artemisiae Argyi 22 ~ 32 parts, Rhizoma Atractylodis 22 ~ 32 parts, Fructus Carpesii 22 ~ 32 parts, Fructus Quisqualis 22 ~ 32 parts, Cortex Dictamni 22 ~ 32 parts, Fructus Atriplicis Sibiricae 22 ~ 32 parts, Periostracum Cicadae 22 ~ 32 parts, Cortex Acanthopancis 22 ~ 32 parts, 22 ~ 32 parts, Herba Spirodelae.
More preferably, treat the medicine of comprehensive beriberi, be made up of the component of following weight portion: Cortex Pseudolaricis 18 parts, Cortex Phellodendri 18 parts, 18 parts, Nicotiana tabacum L., 18 parts, Rhizoma Curcumae Longae, Flos Impatientis 18 parts, Fructus Litseae 18 parts, Herba Pogostemonis 18 parts, Herba Artemisiae Annuae 18 parts, Radix Arnebiae (Radix Lithospermi) 30 parts, Herba Houttuyniae 30 parts, Herba Artemisiae Scopariae 30 parts, Folium Artemisiae Argyi 30 parts, Rhizoma Atractylodis 30 parts, Fructus Carpesii 30 parts, Fructus Quisqualis 30 parts, Cortex Dictamni 30 parts, Fructus Atriplicis Sibiricae 30 parts, Periostracum Cicadae 30 parts, Cortex Acanthopancis 30 parts, 30 parts, Herba Spirodelae.
The dosage form of Chinese herbal medicine of the present invention can be the medically acceptable dosage form such as lotion, tincture, cream, ointment, plaster, and their preparation method, supplementary product consumption are undertaken by existing common process.
The pharmacology of each component that the present invention adopts is as follows:
Cortex Pseudolaricis, is again Cortex Pseudolaricis, pseudolaricis,cortex, is conventional Chinese medicine.Cortex Pseudolaricis tincture is containing Cortex Pseudolaricis acid about 0.8%.Another name: Cortex Pseudolaricis, Jing Pishu.Derive from root bark and the near root bark of pinaceae plant golden larch pseudolarixamabilis (Nelson) Regd. [p.kaempferiGord].Cure mainly: Anti-Puritic and insecticidal.For trick tinea, neurodermatitis, eczema, leprosy dysentery head.Put on the skin outside external root bark or near root bark steeping in wine (Cortex Pseudolaricis tincture); Or porphyrize powder dresses affected part with vinegar.Medicinal part, the bark of golden larch or root bark.Meridian distribution of property and flavor, pungent, temperature.Poisonous.Return lung meridian.Effect is classified, anthelmintic.Effect, Anti-Puritic and insecticidal.Cure mainly trick tinea, local neurodermatitis, eczema, leprosy dysentery head.Usage and dosage, infusing drugs in wine is embrocated or is ground into powder and dresses.
Cortex Phellodendri (hu á ngb ò), Chinese medicine name.For the dry bark of rutaceae wampee PhellodendronchinenseSchneid..Function: have heat clearing and damp drying, pathogenic fire purging removes steams, effect of detoxification sore treatment.Cure mainly: for damp-heat dysentery, jaundice dark coloured urine, leukorrhagia pudendal pruritus, the puckery pain of pyretic stranguria, beriberi flaccidity is knitted, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema eczema.Stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire.For hyperactivity of fire caused by deficiency of YIN, night sweat hectic fever due to YIN-deficiency.
Nicotiana tabacum L., annual or limited perennial herb, Solanaceae.Effect: 1. " the SHENGCAO property of medicine is standby to be wanted ": disappear general edema with yellowish skin, beats medicated porridge food.2. " south of the Five Ridges gather medicinal herbs record ": dispelling the wind and dampness pathogens foot pain, washing is decocted.3. " Luchuan book on Chinese herbal medicine ": reducing swelling and alleviating pain, control treating swelling and pain by traumatic injury, infusing drugs in wine takes or mashes wine and fries deposited.4. " Nanning City's medicine will ": parasite killing, detumescence, hemostasis.Take orally and control metrorrhagia, preventing phlegm from forming and stopping coughing, toothache (pot water contains).Rotten skin ulcer is washed in external; Mash and add urine and boil, external application, controls the swelling of scrotum testis.
Cure mainly: harness the Yellow River swollen, gout, metrorrhagia, treating swelling and pain by traumatic injury, toothache, scrofula, carbuncle skin ulcer, eczema, dermatitis.
Rhizoma Curcumae Longae (Classification system: CurcumalongaL.) has another name called: Radix Curcumae, tripod perfume, milli life, Dioscorea zingiberensis etc.Rhizoma Curcumae Longae Musales, Zingiberaceae, Curcuma herbaceos perennial, Rhizoma Curcumae Longae energy circulation of qi promoting removing blood stasis with potent drugs, inducing menstruation to relieve menalgia.Cure mainly chest and abdomen swelling and pain, shoulder arm arthralgia pain, unbearably pained, puerperal blood pain, skin ulcer tinea onset, menoxenia, amenorrhea, traumatic injury.Yellow food colour can be extracted again; Contained curcumin can perform an analysis chemical reagent.
Flos Impatientis, another name: Flos Impatientis, Semen Impatientis, Caulis Impatientis, Latin literary fame: ImpatiensbalsaminaL. Sapindales, Balsaminaceae, impatiens annual herb flowers, [1] Herb divides root, stem, leaf, flower, fruit and seed six parts.Because its fresh idea, wing, tail, foot all stick up so as phoenix shape, therefore have another name called buttercup.Stem and seed are used as medicine.Stem has wind-damp dispelling, invigorates blood circulation, the effect of pain relieving, for treating rheumatic arthralgia, joint stuffiness; Seed claims " Semen Impatientis ", has the effect of softening the hard mass, removing food stagnancy, for controlling dysphagic, fishbone caught in throat, abdominal mass, amenorrhea.
Fructus Litseae, has another name called cubeb litsen tree, Tetranthera citrata, Alpinia japonica (Thunb.) Miq., Litsea chenii, Fructus Litseae pungentis, Lauraceae, Litsea machaka or dungarunga.Fructus Litseae has effect of warming spleen and stomach for dispelling cold, regulating QI to relieve pain, can be used for the disease such as singultus vomiting, epigastric pain caused by cold syndrome of the stomach, also can be used for the turbid urine that colic of cold type stomachache, sympotoms caused by cold factors dysuria and children's's stagnancy of cold-damp cause, also can treat the diseases such as anemofrigid cold, cough and asthma, dyspepsia.Mash external application with Fructus Litseae leaf, cellulitis furuncle and phyma pain can be treated; Litsea cubeba root decoct hydro-thermal apply or hot dipping can treat rheumatic ostalgia, numb limbs and tense tendons, waist-leg disease and traumatic injury.Litsea cubeba oil also can be used as the raw material of synthesising complex E, K, A etc., to play it in effect pharmaceutically.Due to the unique effect of litsea cubeba oil in disease therapy, be also a focus in clinical research.In addition, Fructus Litseae also have relieving asthma, antiallergic, the anti-rhythm of the heart are normal, antithrombotic, antibacterial, antiviral, anti-trichomonas vaginitis effect.
Herba Pogostemonis, formal name used at school: Agastacherugosa (Fisch.etMey.) O.Ktze.; Have another name called: blending, grey announcement, mountain Fructus Foeniculi etc., belong to tubular flower order, Labiatae herbaceos perennial.Function: eliminating turbid pathogen with aromatics, and middle preventing or arresting vomiting, deliver expelling summer-heat.For turbid damp obstructing in middle-JIAO, gastral cavity painful abdominal mass is vomitted, heat-damp in summer exterior syndrome, hygropyrexia from the beginning of, heating asthenia, uncomfortable in chestly do not relax, cold-damp closes summer-heat, and stomachache is vomited and diarrhoea, nasosinusitis headache.Herba Pogostemonis has sterilizing function, and sucking a leaf can antihalitosis, keeps off infection, and can be used as antiseptic.Summer cooks congee with Herba Pogostemonis or drink-service of making tea, and to heat-damp in summer serious symptom, taste dampness, distension and fullness in the abdomen, limbs are heavily tired, and nausea and vomiting is effective.
Herba Artemisiae Annuae is the dry aerial parts of feverfew Herba Artemisiae Annuae ArtemisiaannuaL..Bud stage is gathered, and extracts aerial parts, and chopping, dries.Ancient name " Qin " (q ì n).Clearing away summer-heat, except steaming, preventing the attack (or recurrence) of malaria.For pathogenic summer-heat heating, fever due to yin deficiency, night fever abating at dawn, hectic fever due to YIN-deficiency consumptive fever, malaria cold and heat, jaundice due to damp-heat.It is a kind of antimalarial drug of cheapness.
Radix Arnebiae (Radix Lithospermi) (formal name used at school: Lithospermumerythrorhizon), another name mountain Radix Arnebiae (Radix Lithospermi), Zi Dan, purple cottonrose hibiscus, small, blood, crow rank grass, Radix Arnebiae (Radix Lithospermi), be Boraginaceae puccoon, perennial herb.Cure mainly: removing heat from blood, invigorate blood circulation, heat clearing away, removing toxic substances.Control warm macule, jaundice due to damp-heat, purpura, tell, be defeated in battle, hematuria, stranguria with turbid discharge, constipation with heat retention, burn, eczema, erysipelas, carbuncle and ulcer.
Herba Houttuyniae (English name HERBAHOUTTUYNIAE) is the medical herbs that Chinese Pharmacopoeia is included, and medical herbs source is the dry aerial parts of saururaceae plant houttuynia cordata (Classification system: HouttuyniacordataThunb.).Cure mainly: heat-clearing and toxic substances removing, inducing diuresis to remove edema.Control pneumonia, lung abscess, hematodiarrhoea, malaria, edema, gonorrhea, leucorrhea, carbuncle, hemorrhoid, proctoptosis, eczema, tinea alba, scabies.
Herba Artemisiae Scopariae, another name Adeps Bovis seu Bubali, Tian Naili, because of dirt, Ma Xian, capillary wormwood, floss Artemisia, Herba Artemisiae Sieversianae, spire Herba Artemisiae Annuae, An Lvcao, Latin literary fame ArtemisiacapillarisThunb. tubular flower order, Compositae, origanum Artemisia are dead through the winter, old of Chun Zeyin and giving birth to, therefore named because of old or Herba Artemisiae Scopariae.Then Artemisia is become to its Seedling of summer, therefore also known as Herba Artemisiae Scopariae.Herba Artemisiae Scopariae clearing away heat-damp and promoting diuresis; Jaundice eliminating.Cure mainly: jaundice, dysuria, eczema pruritus, infectious jaundice type hepatitis.Pharmaceutical research has function of gallbladder promoting, liver function protecting, antipyretic, antiinflammatory, blood fat reducing, blood pressure lowering, the effects such as coronary dilating.
Folium Artemisiae Argyi (formal name used at school: ArtemisiaargyiH.L é v. & Vaniot), another name: ice platform, hold back grass, Artemisia argyi, Artemisia argyi Levl. et Van. var. argyi cv. Qiai, Ai Xiao, Radix Artemisia ordosicae, wormwood, fluffy ligusticumic, Chinese mugwort ﹑ Folium Artemisiae Argyi, moxibustion grass ﹑ cure the yellow careless ﹑ Folium Artemisiae Argyi of careless ﹑ etc.Perennial herb or slightly become suffruticose, plant has enhanced aroma.Folium Artemisiae Argyi nature and flavor are bitter, pungent, warm, enter spleen, liver, kidney.Compendium of Material Medica is recorded: Ai Yiye is used as medicine, the property of warm in nature, bitter in the mouth, nontoxic, pure sun, logical 12 warps, tool recuperating depleted YANG, blood of regulating the flow of vital energy, by effects such as raw, arresting bleeding and miscarriage preventions.Modern experimental research proves, Folium Artemisiae Argyi has antibacterial and antivirus action; Relieving asthma, antitussive and phlegm-dispelling functions; Hemostasis and blood coagulation resisting function; Calmness and anti-allergic effects; Hepatoprotective choleretic effect etc.
Rhizoma Atractylodis, (formal name used at school: AtractylodesLancea).Perennial herb.Stem list is raw or cluster, and stem branch is dredged by arachnoid hair.Effect: drying damp and strengthening spleen, expelling wind and cold, improving eyesight.For distension and fullness in the abdomen, edema of having loose bowels, beriberi flaccidity of feet with lamenness, rheumatic arthralgia, anemofrigid cold, nyctalopia.Main the spleen and stomach being stranded by dampness; Asthenia drowsiness; Born of the same parents' painful abdominal mass abdominal distention; Inappetence; Tell and have loose bowels; Phlegm retention; Damp-edema; Exterior syndrome folder is wet; Head heavy sensation of the body pain; Arthromyodynia warm nature; Podomere is ached.
Fructus Carpesii, Chinese medicine name.For the dry mature fruit of feverfew Radix Carpesii CarpesiumabrotanoidesL..Main component: containing valeric acid, n-caproic acid, oleic acid, dextrorotation linolenic acid, 1 alkane, stigmasterol and the lactone compound such as carpesia-lactone, carabrone in fruit.Seed is containing torilin.FRUCTUS LAPPULAE ECHINATAE seed oil content 19.48%.Fruit, containing volatile oil, contains carpesia-lactone and carabrone in oil; Shang Hanzheng is acid, stigmasterol, melissane and hentriacontane etc.Effect: anthelmintic action, is added dropwise in normal saline 2 Fructus Carpesii 5ml with the sub-tincture 5 of 1% Radix Carpesii, heats 37 DEG C and put into Taenia elliptica again, and 1 ~ 2 minute as a result dead.Mus pinworm, in the Fructus Carpesii liquid of 50% and 25% concentration, after 20 hours, only has minority dead. in the low concentration of 10%, 5%, 1% 24 hours without the phenomena of mortality.
Fructus Quisqualis, another name: scoop and ask son, history gentleman, four gentleman, Latin literary fame: QuisqualisindicaL. Combretum Racemosum, Fructus Quisqualis belong to climbs up by holding on to shape shrub.Effect: 1, anti-dermatophyte effect.Fructus Quisqualis water logging agent has inhibitory action in various degree to dermatophytess such as trichophyton, Trichophyton concentricunm, oidium schoenleinii, Du Ang Shi difficult to understand little spore tinea bacterium, rust little spore tinea bacterium, ulotrichy little spore tinea bacterium, epidermophyton inguinale, star nocardias in vitro.2, pinworm effect is driven.Experimental result for the mice of natural infection Mus pinworm shows, Fructus Quisqualis powder, Fructus Quisqualis and Radix Stemonae powder share all to have and certain drive pinworm effect, and for larva, Fructus Quisqualis powder is invalid, but Fructus Quisqualis powder and Radix Stemonae powder share, then slightly effect.
Cortex Dictamni, another name: Cortex Dictamni, stereotyped writing cattle, Cortex Argyreiae Seguinii Radicis, the fresh grass of sheep, Latin literary fame: CORTEXDICTAMNI Chinese medicine name.For the root bark of Rutaceae herbaceos perennial shaggy-fruited dittany and Dictamnus angustifolius.Main product in Liaoning, Hebei, Sichuan, the ground such as Jiangsu.Spring, Qiu Erji excavate root, and removing silt and rough bark, strip root bark, and section is dry.Raw use.There is heat clearing and damp drying, the effect of removing toxic substances of dispeling the wind.Effect: " property of medicine opinion ": " control all pyretic toxicity wind, aversion to wind, wind skin ulcer, scabies are red rotten, and eyebrow loss of hairs is crisp, and musculus cutaneus is anxious, high fever aversion to cold; Principal solution heat is yellow, wine is yellow, acute jaundice, paddy Huang, labor are yellow." modern study, this product volatile oil has antitumaous effect in vitro.
Fructus Atriplicis Sibiricae, effect: suppressing the hyperactive liver resolving depression, dispelling pathogenic wind for improving eyesight.Cure mainly: for dizziness due to hyperactivity of liver-YANG headache, hypochondriac pain due to stagnation of liverQI, headache due to pathogenic wind-heat, conjunctival congestion and swelling pain, the diseases such as skin pruritus.
Periostracum Cicadae, Chinese medicine name.Its holotype is hollow like Cicadae, slightly bending.Cure mainly: for anemopyretic cold, epidemic febrile disease is from the beginning of, pharyngalgia hoarseness, and measles without adequate eruption, rubella pruritus, cataract, anxious chronic infantile convulsion, tetanus is demonstrate,proved, and the nocturnal fretfulness in infants is uneasy.
Cortex Acanthopancis, Chinese medicine name.For the dry root bark of Araliaceae acanthopanax gracilistylus Acanthopanargracilist μ lusW.W.Smith.Effect: Compendium of Material Medica: [attached side] new.Men and women Zhu Feng, puerperal exposure to wind is especially wonderful.Iron wire grass roots five money, Cortex Acanthopancis one or two, Radix Saposhnikoviae two money.For end.With Gallus Domesticus one jin of severe one, drowned in water, unhairing intestinal, cuts and makes dried meat floss, and being used as medicine, it is even to chop, and lower Oleum Sesami is few a bit, and parching to brown color, measures with people and boil into wine.First decoct thick soup with Solanum lyratum Thunb., shower head body, be food chicken of drinking, send sticky sweat and namely heal.If do not taken a shower, must send urticaria, be more.Cure mainly: for Bi condition, muscles and bones flaccidity is soft, children's's walking retardation in children, and body void is weak, edema, beriberi.
Herba Spirodelae (Lemnaminor), also known as: blue or green duckweed, Tian Ping, Herba Spirodelae grass, water Herba Spirodelae, duckweed grass are Lemnaceae water surface floating plants.Chemical composition: containing the water soluble vitamins such as volume vitamin B1, B2, C, luteolin-7-β-glycoside.Flavonoid and the materials such as iodine, bromine such as 8-hydroxyl luteolin-8-β-glycoside.Its polysaccharide is the abundant source of D-apiose.Still resinous, waxiness, steroid class, chlorophyll, sugar, protein, phlegmatic temperament, tannin etc.Pharmacological action: 1, to cardiovascular effect.Aqueous extract causes the frog heart of exhaustion to have cardiotonic to quinine, and calcium can strengthen it, and heavy dose makes heart stop at relaxing period; And can blood pressure be made to increase by vasoconstrictive.2, refrigeration function.Decoct and preserved material 2 gs/kg, per os gives the rabbit generated heat because of injection typhoid fever mixed vaccine, proves faint refrigeration function.3, other effects.Antibacterial, malaria experiment is feminine gender, has killing action at laboratory and scene to Ability of Culex Pipiens Larvae and tumbler.Effect: enter lung meridian.Diaphoresis, dispels the wind, row water, heat clearing away, removing toxic substances.Cure mainly: row hot carbuncle when controlling, macule is not saturating, wind heat pain rash, skin pruritus, edema, amenorrhea, and skin ulcer tinea, erysipelas, scalds.
Chinese herbal medicine of the present invention has the advantage of short treating period, instant effect to comprehensive beriberi, and energy quick sterilization is antipruritic, shrinks foot pore, prevents the excessive loss of foot moisture, helps to repair foot horny layer, promotes the skin healing of chapping.
Detailed description of the invention
Explain explanation the present invention further below in conjunction with specific embodiment, but the present invention is not limited only to following examples.
Embodiment 1
A kind of medicine for the treatment of comprehensive beriberi, by weight, each component of composition is: Cortex Pseudolaricis 7 parts, Cortex Phellodendri 28 parts, 7 parts, Nicotiana tabacum L., 28 parts, Rhizoma Curcumae Longae, Flos Impatientis 7 parts, Fructus Litseae 28 parts, Herba Pogostemonis 7 parts, Herba Artemisiae Annuae 28 parts, Radix Arnebiae (Radix Lithospermi) 18 parts, Herba Houttuyniae 35 parts, Herba Artemisiae Scopariae 185 parts, Folium Artemisiae Argyi 35 parts, Rhizoma Atractylodis 18 parts, Fructus Carpesii 35 parts, Fructus Quisqualis 18 parts, Cortex Dictamni 35 parts, Fructus Atriplicis Sibiricae 18 parts, Periostracum Cicadae 35 parts, Cortex Acanthopancis 18 parts, 35 parts, Herba Spirodelae.
Above each raw material is taken by proportional quantity, decoct with water 3 times, add 12 times of water gagings the 1st time, decoct 4 hours, add 6 times of water gagings 2nd time, decoct 2 hours, add 3 times of water gagings the 3rd time, decoct 1 hour, collecting decoction, filter, filtrate is concentrated into the solution that relative density is 1.15 (surveying when 60 DEG C), obtained lotion.
Embodiment 2
A kind of medicine for the treatment of comprehensive beriberi, by weight, each component of composition is: Cortex Pseudolaricis 28 parts, Cortex Phellodendri 7 parts, 28 parts, Nicotiana tabacum L., 7 parts, Rhizoma Curcumae Longae, Flos Impatientis 28 parts, Fructus Litseae 7 parts, Herba Pogostemonis 28 parts, Herba Artemisiae Annuae 7 parts, Radix Arnebiae (Radix Lithospermi) 35 parts, Herba Houttuyniae 18 parts, Herba Artemisiae Scopariae 35 parts, Folium Artemisiae Argyi 18 parts, Rhizoma Atractylodis 35 parts, Fructus Carpesii 18 parts, Fructus Quisqualis 35 parts, Cortex Dictamni 18 parts, Fructus Atriplicis Sibiricae 35 parts, Periostracum Cicadae 18 parts, Cortex Acanthopancis 35 parts, 18 parts, Herba Spirodelae.
Take above each raw material by proportional quantity, decoct with water 3 times, add 6 times of water gagings the 1st time, decoct 2 hours, add 3 times of water gagings 2nd time, decoct 1.5 hours, add 1.5 times of water gagings the 3rd time, decoct 1 hour, collecting decoction, filters, and filtrate is concentrated into the extractum that relative density is 1.5 (surveying when 70 DEG C), add medical alcohol, obtain tincture.
Embodiment 3
A kind of medicine for the treatment of comprehensive beriberi, by weight, each component of composition is: Cortex Pseudolaricis 12 parts, Cortex Phellodendri 20 parts, 12 parts, Nicotiana tabacum L., 20 parts, Rhizoma Curcumae Longae, Flos Impatientis 12 parts, Fructus Litseae 20 parts, Herba Pogostemonis 12 parts, Herba Artemisiae Annuae 20 parts, Radix Arnebiae (Radix Lithospermi) 22 parts, Herba Houttuyniae 32 parts, Herba Artemisiae Scopariae 22 parts, Folium Artemisiae Argyi 32 parts, Rhizoma Atractylodis 22 parts, Fructus Carpesii 32 parts, Fructus Quisqualis 22 parts, Cortex Dictamni 32 parts, Fructus Atriplicis Sibiricae 22 parts, Periostracum Cicadae 32 parts, Cortex Acanthopancis 22 parts, 32 parts, Herba Spirodelae.
Above each raw material is taken by proportional quantity, decoct with water 3 times, add 6 times of water gagings the 1st time, decoct 2 hours, add 3 times of water gagings 2nd time, decoction hour, adds 2 times of water gagings the 3rd time, decocts 1 hour, collecting decoction, filter, filtrate is concentrated into the extractum that relative density is 1.75 (surveying when 70 DEG C), adds the aluminium-magnesium silicate cream of conventional amount used.
Embodiment 4
A kind of medicine for the treatment of comprehensive beriberi, by weight, each component of composition is: Cortex Pseudolaricis 20 parts, Cortex Phellodendri 12 parts, 20 parts, Nicotiana tabacum L., 12 parts, Rhizoma Curcumae Longae, Flos Impatientis 20 parts, Fructus Litseae 12 parts, Herba Pogostemonis 20 parts, Herba Artemisiae Annuae 12 parts, Radix Arnebiae (Radix Lithospermi) 32 parts, Herba Houttuyniae 22 parts, Herba Artemisiae Scopariae 32 parts, Folium Artemisiae Argyi 22 parts, Rhizoma Atractylodis 32 parts, Fructus Carpesii 22 parts, Fructus Quisqualis 32 parts, Cortex Dictamni 22 parts, Fructus Atriplicis Sibiricae 32 parts, Periostracum Cicadae 2 parts, Cortex Acanthopancis 32 parts, 22 parts, Herba Spirodelae.
Above each raw material is taken by proportional quantity, decoct with water 3 times, add 4 times of water gagings the 1st time, decoct 2 hours, add 3 times of water gagings 2nd time, decoct 1.5 hours, add 2 times of water gagings the 3rd time, decoct 0.5 hour, collecting decoction, filter, filtrate is concentrated into the thick paste that relative density is 1.65 (surveying when 60 DEG C), and the sorbitol fatty acid methyl ester adjuvant adding conventional amount used obtains ointment.
Embodiment 5
A kind of medicine for the treatment of comprehensive beriberi, by weight, each component of composition is: Cortex Pseudolaricis 18 parts, Cortex Phellodendri 18 parts, 18 parts, Nicotiana tabacum L., 18 parts, Rhizoma Curcumae Longae, Flos Impatientis 18 parts, Fructus Litseae 18 parts, Herba Pogostemonis 18 parts, Herba Artemisiae Annuae 18 parts, Radix Arnebiae (Radix Lithospermi) 30 parts, Herba Houttuyniae 30 parts, Herba Artemisiae Scopariae 30 parts, Folium Artemisiae Argyi 30 parts, Rhizoma Atractylodis 30 parts, Fructus Carpesii 30 parts, Fructus Quisqualis 30 parts, Cortex Dictamni 30 parts, Fructus Atriplicis Sibiricae 30 parts, Periostracum Cicadae 30 parts, Cortex Acanthopancis 30 parts, 30 parts, Herba Spirodelae.
Above each raw material is taken by proportional quantity, decoct with water 3 times, add 3 times of water gagings the 1st time, decoct 2 hours, add 2 times of water gagings 2nd time, decoct 1.5 hours, add 1 times of water gaging the 3rd time, decoct 0.5 hour, collecting decoction, filter, filtrate is concentrated into the thick paste that relative density is 1.85 (surveying when 60 DEG C), and the Colophonium adding conventional amount used obtains plaster.
Experimental example: Chinese herbal medicine of the present invention is to the clinical efficacy of comprehensive beriberi
Experiment material: Chinese herbal medicine prepared by the embodiment of the present invention 5.
Experiment place: Qinzhou healthcare hospital for women & children.
1, case and method
2008-2012, connects and controls Patients with 300 Cases, male 165 example, women 135 example, the age 9-60 year.Symptom: moist between toe, dipping turns white, there is phlysis, wall thickness in local, bleb liquid is clear, chaps pain in vola.
Usage and dosage: Chinese herbal medicine prepared by the embodiment of the present invention 5, every day 3 times, get appropriate plaster at every turn and be applied to affected part, 10d is a course for the treatment of, and this experimental therapy time is 1 course for the treatment of.
2, efficacy determination
Be as the criterion according to clinical symptom disappearance, be divided into recovery from illness, effective, effective, invalid.
Recovery from illness: Clinical symptom and sign disappears, between toe, humidity recovers normal, and blister disappears completely, and vola chapped skin recovers normal, and pruritis disappears completely.
Effective: the basic or major part of Clinical symptom and sign disappears, and have moist phenomenon between part toe, blister disappears substantially, and most of vola chapped skin recovers normal, occurs pruritis once in a while.
Invalid: Clinical symptom and sign without improvement, foot pruritus without obviously alleviating situation, foot blister without significant change, moist degree between toe, chap situation in vola, comparatively before treatment without significant change.
3, curative effect is summed up
| Recovery from illness | Effective | Invalid | Effective percentage | |
| After the course for the treatment of | 87 | 10 | 3 | 97％ |
This therapeutic process, have no adverse reaction appearance, inner recurrence in a year after drug withdrawal.Be not difficult to find out from this experiment, Chinese herbal medicine of the present invention has significant curative effect to comprehensive beriberi.
Claims (3)
1. treat the medicine of comprehensive beriberi for one kind, it is characterized in that, be made up of the component of following weight portion: Cortex Pseudolaricis 7 ~ 28 parts, Cortex Phellodendri 7 ~ 28 parts, 7 ~ 28 parts, Nicotiana tabacum L., 7 ~ 28 parts, Rhizoma Curcumae Longae, Flos Impatientis 7 ~ 28 parts, Fructus Litseae 7 ~ 28 parts, Herba Pogostemonis 7 ~ 28 parts, Herba Artemisiae Annuae 7 ~ 28 parts, Radix Arnebiae (Radix Lithospermi) 18 ~ 35 parts, Herba Houttuyniae 18 ~ 35 parts, Herba Artemisiae Scopariae 18 ~ 35 parts, Folium Artemisiae Argyi 18 ~ 35 parts, Rhizoma Atractylodis 18 ~ 35 parts, Fructus Carpesii 18 ~ 35 parts, Fructus Quisqualis 18 ~ 35 parts, Cortex Dictamni 18 ~ 35 parts, Fructus Atriplicis Sibiricae 18 ~ 35 parts, Periostracum Cicadae 18 ~ 35 parts, Cortex Acanthopancis 18 ~ 35 parts, 18 ~ 35 parts, Herba Spirodelae.
2. the medicine of the comprehensive beriberi for the treatment of according to claim 1, it is characterized in that, be made up of the component of following weight portion: Cortex Pseudolaricis 12 ~ 20 parts, Cortex Phellodendri 12 ~ 20 parts, 12 ~ 20 parts, Nicotiana tabacum L., 12 ~ 20 parts, Rhizoma Curcumae Longae, Flos Impatientis 12 ~ 20 parts, Fructus Litseae 12 ~ 20 parts, Herba Pogostemonis 12 ~ 20 parts, Herba Artemisiae Annuae 12 ~ 20 parts, Radix Arnebiae (Radix Lithospermi) 22 ~ 32 parts, Herba Houttuyniae 22 ~ 32 parts, Herba Artemisiae Scopariae 22 ~ 32 parts, Folium Artemisiae Argyi 22 ~ 32 parts, Rhizoma Atractylodis 22 ~ 32 parts, Fructus Carpesii 22 ~ 32 parts, Fructus Quisqualis 22 ~ 32 parts, Cortex Dictamni 22 ~ 32 parts, Fructus Atriplicis Sibiricae 22 ~ 32 parts, Periostracum Cicadae 22 ~ 32 parts, Cortex Acanthopancis 22 ~ 32 parts, 22 ~ 32 parts, Herba Spirodelae.
3. the medicine of the comprehensive beriberi for the treatment of according to claim 1, it is characterized in that, be made up of the component of following weight portion: Cortex Pseudolaricis 18 parts, Cortex Phellodendri 18 parts, 18 parts, Nicotiana tabacum L., 18 parts, Rhizoma Curcumae Longae, Flos Impatientis 18 parts, Fructus Litseae 18 parts, Herba Pogostemonis 18 parts, Herba Artemisiae Annuae 18 parts, Radix Arnebiae (Radix Lithospermi) 30 parts, Herba Houttuyniae 30 parts, Herba Artemisiae Scopariae 30 parts, Folium Artemisiae Argyi 30 parts, Rhizoma Atractylodis 30 parts, Fructus Carpesii 30 parts, Fructus Quisqualis 30 parts, Cortex Dictamni 30 parts, Fructus Atriplicis Sibiricae 30 parts, Periostracum Cicadae 30 parts, Cortex Acanthopancis 30 parts, 30 parts, Herba Spirodelae.
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| CN110694028A (en) * | 2019-10-16 | 2020-01-17 | 贵州国圣堂生物科技有限公司 | Acupoint-soaking foot-protecting liquid with sweet wormwood as raw material and preparation method thereof |
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| CN103432480A (en) * | 2013-08-17 | 2013-12-11 | 马建国 | Medicinal power for treating erosion-type tinea pedis and preparation method of medicinal power |
| CN103933415A (en) * | 2014-04-03 | 2014-07-23 | 安徽省泗州鞋业有限公司 | Traditional Chinese medicine composition for treating tinea pedis and preparation method thereof |
| CN104208245A (en) * | 2014-09-16 | 2014-12-17 | 景颖 | Traditional Chinese medicine medicated bath for tinea of feet and hands and preparation method thereof |
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| CN103432480A (en) * | 2013-08-17 | 2013-12-11 | 马建国 | Medicinal power for treating erosion-type tinea pedis and preparation method of medicinal power |
| CN103933415A (en) * | 2014-04-03 | 2014-07-23 | 安徽省泗州鞋业有限公司 | Traditional Chinese medicine composition for treating tinea pedis and preparation method thereof |
| CN104208245A (en) * | 2014-09-16 | 2014-12-17 | 景颖 | Traditional Chinese medicine medicated bath for tinea of feet and hands and preparation method thereof |
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| CN106236922A (en) * | 2016-08-30 | 2016-12-21 | 重庆主流生物工程有限公司 | A kind of Chinese medicine composition treating tinea pedis or tinea pedis and preparation method thereof |
| CN110694028A (en) * | 2019-10-16 | 2020-01-17 | 贵州国圣堂生物科技有限公司 | Acupoint-soaking foot-protecting liquid with sweet wormwood as raw material and preparation method thereof |
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