WO2018176642A1

WO2018176642A1 - Chinese medicine for treating skin inflammation

Info

Publication number: WO2018176642A1
Application number: PCT/CN2017/088900
Authority: WO
Inventors: 朱子毅
Original assignee: 朱子毅; 朱凤玲
Priority date: 2017-03-27
Filing date: 2017-06-17
Publication date: 2018-10-04
Also published as: CN108653594A

Abstract

A Chinese medicine for treating skin inflammation, prepared with the following ingredients: 30-60 g of a bamboo fruit, 8-24 g of Semen Hydnocarpi, 20-40 g of Radix Astragali, 1-10 g of Radix Achyranthis Bidentatae, 10-30 g of Rhizoma Gastrodiae, 10-40g of beggar-ticks, 10-30 g of lamb's quarters, 15-25 g of Cortex Moutan, 9-18 g of Herba Galii Teneri, 5-20g of Rhizoma Pinelliae, 15-30 g of Fructus Corni, and 9-18 g of Radix Puerariae. The Chinese medicine is suitable to be administered to treat a high-blood pressure patient.

Description

Traditional Chinese medicine for treating dermatitis

[0001] The present invention relates to a therapeutic drug, and belongs to the technical field of medicine, and in particular to a traditional Chinese medicine for treating dermatitis.

[0002] Global climatic conditions are deteriorating, and the incidence of damp-heat disease is increasing year by year. Athlete's foot (also called hand, foot and ankle) as a common damp-heat disease poses a threat to people's health, sweating on the feet, and poor air circulation. Local moist and warm, is conducive to the growth of filamentous fungi, athlete's foot mainly occurs in the toe and toe, most commonly between the three to four toes, the soles of the feet may also develop due to the disease or scratch, can appear erosion, exudation, Even bacterial infection, pustules and so on. In the prior art, the method for treating athlete's foot is mostly used for external use, but it often occurs repeatedly, and the symptoms are not cured; there are also Chinese medicines taken by internal medicine, but some of the raw materials used have toxic side effects on the kidney, some contain aminophylline, and some have β. - Receptor agonists, some use blood-rich Chinese medicines such as ginseng, etc., these raw materials can cause high blood pressure, these prescriptions are not suitable for middle-aged and elderly people with high blood pressure. In short, Chinese medicine has achieved certain results in the treatment of athlete's foot, but at present there are still the following problems: Some latent virus treatment is not thorough, easy to relapse; single effect, can only solve a single disease; not suitable for middle-aged and elderly people with high blood pressure Take it.

technical problem

[0003] The technical problem to be solved by the present invention is: Inventing a traditional Chinese medicine for treating dermatitis, which is thorough in treatment, prevents recurrence, and has comprehensive curative effect, and is suitable for treating and treating patients with hypertension.

Problem solution

Technical solution

[0004]

The invention is made of the following raw materials: bamboo solid 30-60g, big maple seed 8-24g, astragalus 20-40g, achyranthes 1-lOg, gastrodia 10-30g, Bidens 10-40g, white peony 10-30g , Danpi 15-25g, Eight Immortals 9-18g, Dry Pinellia 5-20g, Hawthorn 15-30g, Pueraria 9-18g.

[0005] The preferred schemes are: bamboo solid 40-50g, big maple, 10-15g, astragalus 25-35g, achyranthes 3-8g, gastrodia 15-25g, Bidens 15-30g, white peony 15-25g, danpi 18- 23g, 8-15g of octagonal grass, 10-15g of dry Pinellia, 18-27g of hawthorn, 12-16g of pueraria.

[0006] More preferred schemes are: bamboo real 42.8, big maple 12.5g, astragalus 29.6g, achyranthes 4.8g, gastrodia 20.5g, Bidens 23.6g, white peony 19.8g, paeonol 19.4g, octagonal grass 12.6 g, dry Pinellia 12.4g, hawthorn 20g, Puerariae 13.8g.

[0007] A preparation method for preparing the traditional Chinese medicine for treating dermatitis according to any one of the above, characterized in that the following steps are taken: selecting the medicinal material according to the formula, sterilizing, drying and pulverizing into a fine powder by using a high pressure steam sterilizer; , mixing, pelleting, drying, pilling, and packaging are the finished products.

[0008] Among the above raw materials, bamboo solid, alias bamboo rice ("Materia Medica"), is the fruit of the grassy plants of the grass family, the taste of the classics, Gan, Ping, into the spleen, stomach. Indications: Yiqi;

[0009] Dafengzi: It is a mature seed of the big maple tree. Sexual taste and return: Xin, hot, poisonous. Into the lungs, liver, hurricane dampness, attacking and killing insects. Indications for leprosy, external treatment of plum sore, sputum, hand back cleft palate.

[0010] Astragalus, also known as Azolla, enhances immune function, liver protection, diuresis, anti-aging, anti-stress, blood pressure and a wide range of antibacterial effects. However, the facts of the evil spirits, qi stagnation and dampness, food stagnation, sputum at the beginning or after the collapse of the hot poison and Sheng Sheng and other evidence, as well as yin deficiency and impotence, must be banned.

[0011] Achyranthes, sexual taste: bitter, sweet, sour, flat. Treatment of virtual fire toothache, athlete's foot edema; cooked, liver and kidney, strong waist and knee; cure waist and knee pain, liver and kidney deficiency, bruises. Return to the classics: return to the liver, kidney. Efficacy: Zhuyu Tongjing, liver and kidney, strong bones and muscles, diuretic Tonglin, blood draw down.

[0012] Gastrodia, taste: sweet, flat, non-toxic. Gas level, bitter taste. Into the spleen, kidney, liver, gallbladder, heart. Efficacy: Interest, wind and shock. Treatment of dizziness, black eyes, head wind headache, limb numbness, hemiplegia, language paralysis, children with epileptic seizures, bloating, under the full, sputum, blood. It has a steady-pressure anti-pressure effect, which is good for the waist and knees and strong for strength.

[0013] Bidens, warm, bitter, non-toxic, whole grass can be used as medicine, with heat, detoxification, dilated, swelling and other effects, in recent years, the drug has a good biphasic regulation of blood pressure, Hypertensive patients can lower blood pressure, and those with lower blood pressure can raise blood pressure to normal. Sexual taste: sweet, light, bitter, slightly cold. Return: liver, lung, large intestine.

[0014] White peony, whole grass can be used as medicine, cool, sweet, flat, with small poison, with dampness and detoxification effect, treating sore , swollen poison, phlegm, phlegm and other symptoms, there are blood pressure, voltage regulation, for the elderly calcium deficiency also have a certain health care function.

[0015] Danpi: bitter, spicy, slightly cold. Heart, liver, kidney. It has the effect of clearing heat and cooling blood, promoting blood circulation and removing blood stasis, and is used for warming poisonous hair spots. It is vomiting blood and blood stasis, night heat and early cold, no sweat bone steaming, menstrual dysmenorrhea, swollen sore poison, falling and hurting.

[0016] Eight Immortals: also known as sawn grass, Lara vine, flying vine, miso grass Kolara genus swine fever or thick leaves Lara vines whole grass. Medicinal properties: The whole grass is slender, easily broken, the surface is grayish green or greenish brown, the gas is slight, the taste is bitter, the taste is bitter, and the sex is slightly cold. Ingredients: Containing alkaloids, fruit containing barley maltamine, gallic acid, etc.; Phyllostachys pubescens. The aerial part contains caroside, vitamin C. According to modern pharmacological research, the drug has antibacterial and anticancer properties.

, clearing heat and detoxification, diuretic Tonglin, swelling and pain relief, for swollen poison, appendicitis, cold fever, hematuria and so on.

[0017] Dry Pinellia, alias old blind, water jade, geography, three-step jump, Ma Yu fruit, etc., tuber into the medicine, can dampness and phlegm, reduce vomiting, use sputum swelling; attending cough, Nausea and vomiting; topical treatment of acute mastitis, acute and chronic suppurative otitis media.

[0018] Hawthorn, a strong astringent medicine, has the effect of nourishing liver and kidney.

[0019] Pueraria, returning to the spleen; stomach. Sexual taste: Gan; Xin; Cool. Efficacy: Decompression of muscles; publication of thorough diagnosis; Shengjinzhike; Shengyang diarrhea, reconciliation medicinal. Indications for exogenous fever, strong head pain, early onset of measles, poor rash, warm thirst, thirst, diarrhea, dysentery, high blood pressure, coronary heart disease.

Advantageous effects of the invention

Beneficial effect

[0020] The implementation of the present invention has the following beneficial effects:

[0021] The toxic and side effects of the invention are small, and the formula is unique and suitable for the athlete's foot syndrome. According to the theory of traditional Chinese medicine, a plurality of drugs are appropriately formulated, and the synergy or resistance between the drugs is used to improve the curative effect and shorten the healing time. To reduce adverse reactions, the Chinese medicine can improve the body's immunity and regulate the mental state in the treatment of the same symptoms. The main causes of athlete's foot include the following: 1. The weather is hot and humid, and the perspiration is not smooth, which causes moisture to accumulate. If it is neglected, it will easily lead to damp fever. 2, wet and rainy, if the physical quality is not good enough, the external wet and turbid gas will take advantage of it. If the spleen is coming back to join in the fun, the wet and turbid gas will accumulate in the body, especially in the organs and meridians. 3, the external pathogenic bacteria take advantage of the virtual into the fungus Infection. The main pathogenesis of athlete's foot is the virtual standard, the virtual and real miscellaneous, the specific manifestation of spleen deficiency and blood stasis. The invention has the bamboo, the big maple, the achyranthes, the dry pinellia and the yellow scorpion, and aims to strengthen the spleen and replenish the qi, and the stomach, nourish the heart and soothe the nerves; the mountain stagnation of the kidney, the acidity of the stagnation, can prevent the jaundice from rising ; Danpi, Baxiancao Huoxue Tongluo detoxification and pain relief; Tianma, Bidens, Baili, Pueraria have both solid, antibacterial, and anti-hypertensive effects. The invention plays the role of strengthening the spleen, promoting blood circulation, collaterals, detoxification and stabilizing, and puts the righting in the first place to boost the righteousness. Otherwise, it is detoxification and detoxification, which is most likely to damage the yang and cause abdominal pain, vomiting, and sorrow. , limb weakness and other discomfort. In the spleen, collaterals, detoxification, the same can also play a role in regulating blood pressure, but also kidney, strong gluten, suitable for the elderly with high blood pressure to choose this drug treatment. The invention not only solves the disease lesions, but also maintains the mental state of the patient, has simple drug composition, rich source and low price; the treatment method is simple, and the burden on the patient is reduced. In addition, the present invention is effective not only for patients with athlete's foot, but also for other diseases such as eczema, dermatitis, dermatitis, heat acne, such as malignant tumor or diabetes, hypertension, coronary heart disease, and the present invention can also be effective. treatment.

Brief description of the drawing

DRAWINGS

[0022] The description paragraph is entered here by typing in the accompanying drawings.

BEST MODE FOR CARRYING OUT THE INVENTION

[0023] The paragraphs describing the best mode of the invention are entered here.

Embodiments of the invention

DETAILED DESCRIPTION

[0025] For a better understanding and implementation, the invention will be described in detail below with reference to specific embodiments.

Embodiment 1

[0027] A traditional Chinese medicine for treating dermatitis is made of the following raw materials: bamboo solid 30g, big maple seed 8g, astragalus 20g, achyranthes lg, gastrodia elata 10g, Bidens pilosula 10g, white peony root 10g, paeonol 15g, octagonal Grass 9g, dry Pinellia 5g, Hawthorn 15g, Pueraria 9g.

Embodiment 2 [0029] A traditional Chinese medicine for treating dermatitis, which is made of the following raw materials: bamboo 60g, big maple 24g, astragalus 40g, achyranthes 10g, gastrodia 30g, Bidens 40g, white peony 30g, paeonol 25g, october Grass 18g, dry Pinellia 20g, hawthorn 30g, Pueraria 18g.

[0030] Example 3

[0031] A traditional Chinese medicine for treating dermatitis, which is made of the following raw materials: bamboo solid 40g, big maple seed 10g, astragalus 25g, achyranthes 3g, gastrodia 15g, Bidens pinching 15g, white peony 15g, paeonol 18g, octagonal Grass 10g, dry Pinellia 10g, Hawthorn 18g, Pueraria 12g.

Embodiment 4

[0033] A traditional Chinese medicine for treating dermatitis, which is made of the following raw materials: bamboo solid 50g, big maple syrup 15g, astragalus 35g, achyranthes 8g, gastrodia 25g, Bidens pilosa 30g, white peony 25g, paeonol 23g, octagonal Grass 15g, dry Pinellia 15g, hawthorn 27g, Pueraria 16g.

Example 5

[0035] A traditional Chinese medicine for treating dermatitis, which is made of the following raw materials: bamboo solid 35g, big maple seed 9g, astragalus 23g, achyranthes 2g, gastrodia 13g, Bidens pilosula 13g, white peony 13g, paeonol 17g, octagonal Grass 10g, dry Pinellia 8g, hawthorn 22g, Pueraria l lg.

Embodiment 6

[0037] A traditional Chinese medicine for treating dermatitis is made of the following raw materials: bamboo solid 45g, big maple spring 12g, astragalus 30g, achyranthes 5g, gastrodia 20g, Bidens 23g, white peony 20g, danpi 20g, eight sen Grass 13g, dry Pinellia 17g, hawthorn 24g, Pueraria 14g.

Example 7

[0039] A traditional Chinese medicine for treating dermatitis, which is made of the following raw materials: bamboo solid 55g, big maple spring 20g, astragalus 37g, achyranthes 9g, gastrodia elata 27g, Bidens pinching 35g, white peony root 28g, paeonol 24g, eight cents Grass 16g, dry Pinellia 20g, Hawthorn 26g, Pueraria 17g.

Embodiment 8

[0041] A traditional Chinese medicine for treating dermatitis, which is made of the following raw materials: Zhushi 42.8, Dafengzi 12.5g, Astragalus 29.6g

, Achyranthes 4.8g, Gastrodia elata 20.5g, Bidens pilosa 23.6g, White peony 19.8g, Danpi 19.4g, Eight Immortals 12.6g, Dry Pinellia 12.4g, Hawthorn 20g, Pueraria 13.8g.

[0042] Preparation method: Each example is prepared by the following steps: [0043] The medicinal materials are selected according to the formula, and are sterilized, dried, pulverized into fine powder, mixed, pelletized, dried, selected, and packaged in a high-pressure steam sterilization cabinet to obtain a finished product.

[0044] Clinical treatment effect:

[0045] Significant and cure criteria: Specifically divided into the following three levels: cure a disease symptoms completely disappeared; good symptoms of a disease disappeared or significantly reduced; invalid one disease has symptoms, no improvement or reduction.

[0046] Clinical Experiment 1 :

[0047] A 35-60 year old dermatitis patient with a history of hypertension was divided into 8 groups (10 persons each), and each of the groups of Examples 1-8 was used to prepare a pill treatment, one dose per day, and water decoction Two warm clothes, taken 7 to 20 days to cure, and blood pressure is stable after taking the drug. All of the above 8 examples have a therapeutic effect on beriberi conditions.

[0048] Clinical Experiment 2:

[0049] In order to verify the clinical and practicality of the present invention, 150 patient experiments were conducted, 35-60 year old dermatitis patients with a history of hypertension, including men and women, and the pill of Example 8 was used. -12 days. All 150 patients had normal blood pressure, 131 cases were cured by dermatitis, 15 cases were improved, and 4 cases were ineffective. The cure rate is as high as 87.33%, and the cure and improvement rate is as high as 97.33%.

[0050] Clinical Trial 3:

[0051] In order to verify the clinical and practicality of the present invention, 120 patient-experienced patients with dermatitis of 35-60 years old with hypertension, including men and women, were selected for the pills of Example 8 and 7 -12 days. 118 cases of blood pressure were normal, 2 cases improved, the cure rate of hypertension was over 98%; 108 cases of dermatitis were cured, 10 cases were improved, 2 cases were ineffective, the cure rate was as high as 90%, and the cure and improvement rate was as high as 98%.

[0052] Clinical Experiment 4:

[0053] 100 cases of dermatitis patients with hypotension were performed, including men and women, and the pills of Example 8 were used for 7-10 days. 78 cases of normal blood pressure, 2 cases improved, 20 cases were ineffective, the cure rate of hypotension was 78%; dermatitis was cured in 88 cases, improved in 10 cases, ineffective in 2 cases, the cure rate was as high as 88%, and the cure and improvement rate was as high as 98%.

[0054] Treatment results:

[0055] A total of 45 patients with refractory dermatitis were treated with the technical solution of Example 8, including 30 males and 15 females. The patient's annual minimum was 30 years old and the maximum was 67 years old, of which 31 cases were 35-55 years old, accounting for 68%. The shortest period of illness is 5 weeks, and the longest is 7 years. Of the 45 patients, 29 had a disease between 10 and 4 years. Press The technical solution of the embodiment 8 is one dose per day, 7 days is a course of treatment, and the treatment is stopped after 2-3 courses of treatment.

[0056] 8 cases were cured in 4 days, 16 cases were cured in 7 days, 12 cases were cured in 8-14 days, and 9 cases were improved after two courses of medication. The cure rate was 53% in one course of treatment, 80% in two courses, and the effective rate was 100%.

[0057] 29 patients with disease between 10 weeks and 4 years, after treatment for 24 courses, 24 cases were cured, the cure rate was 80%; 5 cases with more than 4 years after onset, after two courses Treatment,

Three cases were cured and the cure rate was 60%. Among the 29 patients who recovered, 1 year was followed, 3 of them relapsed, and the recurrence rate was 10%. From this analysis, the therapeutic effect of the medicament of the present invention is better than that of the shorter course of the disease; the curative effect on the intractable disease is good; the recurrence rate after the cure is low.

[0058] Case 1 :

[0059] Patient Zhang, female, 47 years old, visited on July 24, 2016, the hospital was diagnosed with hypertension, occult coronary heart disease, the body dragged the limbs, and the mental state was poor; the treatment with the technical solution of Example 8 Dermatitis, cured after three courses of treatment, normal hypertension returned to normal, palpitations and shortness of breath disappeared, coronary heart disease symptoms were basically eliminated, and mental state was good.

[0060] Case Case 2:

[0061] Patient Cheng, male, 52 years old, hospital examined with hypertension, occult coronary heart disease, visited on August 4, 2016, waist and knees, joint pain; using the technical solution of Example 8 to treat dermatitis After treatment for three courses of treatment, the high blood pressure returned to normal, the symptoms of coronary heart disease were basically eliminated, and joint pain was relieved.

[0062] Case Case 3:

[0063] Patient Guan, male, 48 years old, with eczema, visited on August 23, 2016, treated with the technical solution of Example 8, cured after treatment for one course of treatment, and the symptoms were basically eliminated.

[0064] Case 4:

[0065] Patient Li, female, 48 years old, with cutaneous fistula, itching, contact pain on the elbow, treated on September 23, 2016, treated with the technical solution of Example 8, cured after two courses of treatment, symptoms Basic elimination.

[0066] Case Case 5:

[0067] Patient Zhang, male, 45 years old, with acne and itching pain in his hand, he was treated on October 4, 2016, and was treated with the technical solution of Example 8. After three courses of treatment, the symptoms were basically eliminated.

Case case 6:

[0069] Patient Zhang, female, 49 years old, hospital diagnosed with breast cancer, was treated with the technical solution of Example 8 on March 4, 2016. After six courses of treatment, the condition was basically controlled without signs of proliferation.

[0070] Case 7:

[0071] Patient Liu, male, 59 years old, with diabetes, began to use the technical solution of Example 8 to treat beriberi on June 14, 2016, and cured beriberi after 3 courses of treatment; Diabetes index fasting blood glucose At 6.9 mmol/L, the symptoms of diabetes were basically eliminated.

Industrial applicability

[0072] Enter the paragraph of industrial applicability description here.

Sequence table free content

[0073] Type a sequence table free content description paragraph here.

Claims

Claim

[Claim 1] A traditional Chinese medicine for treating dermatitis, which is prepared from the following raw materials: Bamboo 30-60g

, Big Maple 8-24g, Astragalus 20-40g, Achyranthes l-10g, Gastrodia 10-30g, Bidens 10-40 g, White Pelican 10-30g, Dan Pei 15-25g, Eight Immortals 9-18g, Dry Pinellia 5-20g, Hawthorn 15 -30g, Pueraria 9-18g.

A traditional Chinese medicine for treating dermatitis according to claim 1, which is prepared from the following raw materials: 40-50 g of bamboo, 10-15 g of big maple, 25-35 g of astragalus, 3-8 g of achyranthes, gastrodia elata 15-25g, Bidensius 15-30g, White Pelican 15-25g, Danpi 18-23g, Eight Immortals 10-15g, Dry Pinellia 10-15g, Hawthorn 18-27g, Pueraria 12-16g.

A traditional Chinese medicine for treating dermatitis according to claim 1 or 2, which is prepared from the following raw materials: bamboo solid 42.8, big maple, 12.5 g, astragalus 29.6 g, achyranthes 4.8 g, gastrodia 20 .5 g , Biscalyx 23.6g, white peony 19.8g, paeonol 19.4g, octagonal grass 12.6g, dry Pinellia 12.4 g, hawthorn 20g, Puerariae 13.8g.

A preparation method for preparing the traditional Chinese medicine for treating dermatitis according to any of the preceding claims, characterized in that the following steps are taken: the medicine is selected according to the formula, sterilized, dried and pulverized into fine powder by a high pressure steam sterilization cabinet, Mixing, pilling, drying, pilling, and packaging are the finished products.