CN105534829A - Anti-aging plant extract composition and application thereof to cosmetics - Google Patents
Anti-aging plant extract composition and application thereof to cosmetics Download PDFInfo
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- CN105534829A CN105534829A CN201610117661.1A CN201610117661A CN105534829A CN 105534829 A CN105534829 A CN 105534829A CN 201610117661 A CN201610117661 A CN 201610117661A CN 105534829 A CN105534829 A CN 105534829A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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Abstract
The invention discloses anti-aging plant extract composition. The composition comprises extracts of raw materials in parts by weight as follows: 40-50 parts of mahonia, 30-40 parts of lespedeza, 15-25 parts of shiny bramble and 10-20 parts of belvedere fruits. Compared with the prior art, the plant extract composition with an anti-aging effect takes natural and non-irritating antioxidant extracts as main materials, some anti-aging auxiliary plant active ingredients such as microelements, an immunopotentiator and the like are added properly, and the composition is natural, non-toxic and balanced in nutrition, can be absorbed by skin easily, can increase skin gloss, remove winkles, moisten skin and the like and solves the problem that pure plant skin-care products in the prior art only focus on addition of anti-aging ingredients and neglect balance among the active ingredients.
Description
Technical field
The present invention relates to plant extract compositions cosmetic field, particularly relate to a kind of plant extract compositions can resisting skin aging.
Background technology
Skin is the tissue that body surface wraps in outside muscle, is the maximum organ of human body, carries protection health, perspire, feels cold and hot and the function such as pressure.With advancing age, skin declines gradually to environment change adaptability, and then occurs the old and feeble features such as wrinkle, lax, jaundice, mottle.Old and feeble reason has a lot to cause skin to occur, since British scholar Harman proposed " free-radical theory " in 1956 first in United States Atomic Energy Commission, " free-radical theory " becomes old and feeble core theory gradually.Free radical is the intermediate product of body homergy, and respond is very strong, once excess accumulation will produce irreversible damage to materials such as nucleic acid, sugar, protein, finally causes a series of senile symptom.Developing the harmful free radicals that effective antioxidant carrys out purged body inner accumulated is to antidotal powerful measure.One of mechanism of action of antioxidant is that some transition metal ionss of chelating are as Fe
2+, Cu
2+, make these metal ions remain on certain low-oxidation-state, prevent it by Fenton (Fe
2++ H
2o
2→ Fe
3++ OH
-+ OH) or Haber-Weiss (O
2.
-+ H
2o
2→ OH+OH
-+ O
2)) react and produce OH.Free radical and transition metal ions play important function in the metabolic activity of the mankind, and supplementing in time antioxidant can too much free radical and regulate the balance of transition metal ions, slow down aging in purged body.
Advocating the society of green, nutrition, safety and Health, natural non-stimulated pure vegetalization cosmetic has become consumer and has improved skin, the necessary of " with protecting the youth ".And Extraction and isolation antioxidant is one of current effective way from natural plants.But the pure plant skin care item sold in the market only focus on the various interpolation with direct or indirect antioxidation active component mostly, and ignore the balance between each active component.The antioxidant of exploitation Nantural non-toxic equilibrium is social need growing at present, significant.
Summary of the invention
The object of the present invention is to provide a kind of Nantural non-toxic, the pure plant extract compositions with senile-resistant efficacy balanced in nutrition, wherein based on natural non-stimulated antioxidant extract, suitable interpolation some can the auxiliary active components of plants of antidotal such as trace element, immunostimulant etc., only focus on the interpolation of aging ingredient and the equilibrium problem ignored between each active component to solving pure plant skin care item in prior art.
For addressing the aforementioned drawbacks technical scheme of the present invention for providing a kind of defying age plant extract compositions, its component is the extract of following weight part ratio raw material: Mahonia fortunei (Lindl.) Fedde 40-50 part, Caulis Seu Folium Lespedezae Bicoloris 30-40 part, Radix Zanthoxyli 15-25 part, Fructus Kochiae 10-20 part.
Mahonia fortunei (Lindl.) Fedde [Mahoniafortunei (Lindl.) Fedde], calls yellow nandina, is Berberidaceae Mahonia fortunei (Lindl.) Fedde platymiscium.Be rich in the chemical compositions such as alkaloid, volatile oil, total flavones.Its extract has very strong antioxidation, to DPPH (1,1-diphenyl-2-trinitrophenyl-hydrazine) and ABTS
+[2,2-azino-two (3-ethyl-benzothiazole-6-sulfonic acid) di-ammonium salts] has good scavenging action, to transition metal ions Fe
2+, Cu
2+there is good chelation, indirectly can suppress the generation of OH free radical.The all right anti-lipid peroxidation of its active component, suppresses keratinocyte hyperplasia, suppresses the autoxidation speed of pyrogallol in addition, and removing the OH of Fenton reaction generation, is excellent antioxidant.
Caulis Seu Folium Lespedezae Bicoloris (LespedezabicolorTurcz.), having another name called branch recklessly, is pulse family Lespedeza plant.Be rich in the antioxidant contents such as flavone, vitamin, organic acid, plant polyphenol.Wherein flavone compound can scavenging free radicals, oil-control oxidative rancidity, suppress Linoleic Acid Oxidation, suppress dopachrome interconvertible enzyme active, remarkable minimizing malonaldehyde (MDA, the index substance of Lipid peroxidation metabolism) generate, improve the activity of superoxide dismutase, the peroxidation that the evil of the light loss suffered by phosphatidylcholine liposome causes can be prevented simultaneously, protection Skin Cell, not by the impact of oxygen-derived free radicals over oxidation, strengthens its antidotal ability; The enhancing antioxidative ability that vitamin C, vitamin E, beta-carotene not only can be worked in coordination with also is prooxidant simultaneously; Folic acid can accelerate basal layer cell division, promotes that horny layer comes off; Tannin can absorb ultraviolet, restraint of tyrosinase and peroxidase, and can be used as hydrogen donor elimination free radical.
Radix Zanthoxyli Zanthoxylumnitidum (Roxb.) DC., has another name called Radix Zanthoxyli, is Rutaceae xanthoxylum.Be rich in alkaloid, trace element, its extract has immunoregulation effect on the one hand, on the other hand energy Scavenger of ROS, as removed the O that alkaline 1,2,3,-thrihydroxy-benzene system produces
-2, suppress by Fe
-2the liver homogenate lipid peroxidation that-cysteine brings out, significantly improves Liver Superoxide Dismutase Activity SOD active.Trace element is the active center of multiple crucial antioxidase in addition, as Cu, Zn is the active center of superoxide dismutase (CuZn-SOD), Se is cysteine, the component of glutathione peroxidase (GSH-Px), supplement appropriate trace element in time and effectively can catch free electron, degrading activity oxygen, prevent the physiological function of peroxidation insult cell and body, Zn can improve the activity of archaeal dna polymerase and RNA polymerase simultaneously, strengthen replication capacity and the repair function of DNA, the stability of Cell protection film makes its attack exempting from free radical and infringement.
The Fructus Kochiae [Kochiascoparia (L.) Schrad.], another name oregano, for Chenopodiaceae Kochia plant, the chemical composition such as volatile oil, saponins is rich in extract, the wherein immunologic function of volatile oil energy enhancing body, thus prevention and postponement normal immunological deterioration, conditioning ageing process.And saponin can improve superoxide dismutase in body (SOD), catalase (CAT), glutathione peroxidase (GSH-Px) activity; reduce over lipid oxide (LPO), malonaldehyde (MDA) content; promote neurotransmitter Ach release, stop neuron to produce excess nitrate; accelerate the synthesis of nucleic acid in vivo and protein simultaneously; make dermal fibroblasts vitality restoration; the collagen fiber of protection ageing skin and elastic fibers, slow down aging.
Preferably, the extract of described weight part ratio raw material is: Mahonia fortunei (Lindl.) Fedde 45 parts, Caulis Seu Folium Lespedezae Bicoloris 35 parts, Radix Zanthoxyli 20 parts, the Fructus Kochiae 15 parts.
Another technical scheme of the present invention, for providing the preparation method of above-mentioned a kind of defying age plant extract compositions, comprises the following steps:
(1) take raw material by weight, being crushed to granular size is that after 80-100 order, mixing loads the extraction column being placed in 135-150 DEG C of calorstat;
(2) under the constant-pressure conditions of 5.5-7MPa, pump into ultra-pure water by infusion pump by the ratio of solvent of 0.1-0.2mL/mg in extraction column, flow velocity is 0.8-1.0mL/min, collects extracting solution with stop valve simultaneously;
(3) after 25-35min, the extracting solution of collection is placed in 60 DEG C of baking ovens and dries, obtain defying age plant extract compositions of the present invention.
Another technical scheme of the present invention is to provide the application of above-mentioned a kind of defying age plant extract compositions in cosmetics.
The present invention also has a technical scheme to be to provide anti-aging cosmetics, and described anti-aging cosmetics comprises above-mentioned defying age plant extract compositions, and described defying age plant extract compositions accounts for the 4.00%-30.00% of cosmetics gross weight.
Preferably, described defying age plant extract compositions accounts for the 6.00%-20.00% of cosmetics gross weight.
The invention provides containing above-mentioned one containing defying age plant extract compositions facial film, described facial film comprises the component of following percentage by weight:
Hydroxyethyl-cellulose: 0.04-0.08wt%,
Hyaluronate sodium: 0.04-0.06wt%,
Carbomer: 0.04-0.06wt%,
Glycerol: 5.00-9.00wt%,
Defying age plant extract compositions: 4.00-30.00wt%,
Butanediol: 2.50-5.80wt%,
Betanin: 1.80-4.30wt%,
Jojoba butter (water): 0.04-0.05wt%,
Methyl hydroxybenzoate: 0.09-0.12wt%,
Triethanolamine: 0.04-0.06wt%,
The mixture of Fructus Hordei Germinatus oligose glucoside and hydrogenated starch hydrolysate 1:1: 1.43-1.75wt%,
Glycerol polymethacrylates, the mixture of propylene glycol and Gantrez AN-119 1:1:1: 2.00-4.00wt%,
The mixture of diazolidinyl urea and iodine propilolic alcohol butyl mephenesin Carbamate 1:1: 0.14-0.31wt%,
The mixture of Euglena gracilis polysaccharide and hydrolytic collagen 1:1: 0.04-0.06wt%,
Deionized water: 44.35-82.81wt%.
Compared with prior art, a kind of Nantural non-toxic provided by the invention, the pure plant extract compositions with senile-resistant efficacy balanced in nutrition, based on natural non-stimulated antioxidant extract, suitable interpolation some can the auxiliary active components of plants of antidotal such as trace element, immunostimulant etc., to highlight skin gloss, the form such as microgroove, moistening skin of eliminating shows, and solves pure plant skin care item in prior art and only focuses on the interpolation of aging ingredient and the equilibrium problem ignored between each active component.
Detailed description of the invention
Below in conjunction with embodiment in detail the present invention is described in detail.
The experimental technique used in following embodiment if no special instructions, is conventional method.
Instrument used in following embodiment, reagent, material etc., if no special instructions, all can obtain from commercial channels.
Embodiment 1
(1) raw material is taken by following proportioning: Mahonia fortunei (Lindl.) Fedde 40g, Caulis Seu Folium Lespedezae Bicoloris 30g, Radix Zanthoxyli 15g, Fructus Kochiae 10g, being crushed to granular size is that after 80 orders, mixing loads the extraction column (abstraction instrument is purchased from Jinan A Erwa Instrument Ltd.) being placed in 135 DEG C of calorstats;
(2) under the constant-pressure conditions of 5.5MPa, pump into ultra-pure water by infusion pump by the ratio of solvent of 0.1mL/mg in extraction column, flow velocity is 0.8mL/min, collects extracting solution with stop valve simultaneously;
(3), after 25min, the extracting solution of collection is placed in 60 DEG C of baking ovens (Dongguan City Jian Qiao testing equipment company limited) and dries, obtain defying age plant extract compositions of the present invention.
Comparative example 1
(1) take raw material Mahonia fortunei (Lindl.) Fedde 40g, being crushed to granular size is that after 80 orders, mixing loads the extraction column (abstraction instrument is purchased from Jinan A Erwa Instrument Ltd.) being placed in 135 DEG C of calorstats;
(2) under the constant-pressure conditions of 5.5MPa, pump into ultra-pure water by infusion pump by the ratio of solvent of 0.1mL/mg in extraction column, flow velocity is 0.8mL/min, collects extracting solution with stop valve simultaneously;
(3), after 25min, the extracting solution of collection is placed in 60 DEG C of baking ovens (Dongguan City Jian Qiao testing equipment company limited) and dries, obtain defying age plant extract compositions of the present invention.
Embodiment 2
(1) raw material is taken by following proportioning: Mahonia fortunei (Lindl.) Fedde 45g, Caulis Seu Folium Lespedezae Bicoloris 35g, Radix Zanthoxyli 20g, Fructus Kochiae 15g, being crushed to granular size is that after 90 orders, mixing loads the extraction column (abstraction instrument is purchased from Jinan A Erwa Instrument Ltd.) being placed in 142.5 DEG C of calorstats;
(2) under the constant-pressure conditions of 6.25MPa, pump into ultra-pure water by infusion pump by the ratio of solvent of 0.15mL/mg in extraction column, flow velocity is 0.9mL/min, collects extracting solution with stop valve simultaneously;
(3), after 30min, the extracting solution of collection is placed in 60 DEG C of baking ovens (Dongguan City Jian Qiao testing equipment company limited) and dries, obtain defying age plant extract compositions of the present invention.
Comparative example 2
(1) take raw material by following proportioning: Mahonia fortunei (Lindl.) Fedde 45g, Caulis Seu Folium Lespedezae Bicoloris 35g, being crushed to granular size is that after 90 orders, mixing loads the extraction column (abstraction instrument is purchased from Jinan A Erwa Instrument Ltd.) being placed in 142.5 DEG C of calorstats;
(2) under the constant-pressure conditions of 6.25MPa, pump into ultra-pure water by infusion pump by the ratio of solvent of 0.15mL/mg in extraction column, flow velocity is 0.9mL/min, collects extracting solution with stop valve simultaneously;
(3), after 30min, the extracting solution of collection is placed in 60 DEG C of baking ovens (Dongguan City Jian Qiao testing equipment company limited) and dries, obtain defying age plant extract compositions of the present invention.
Embodiment 3
(1) raw material is taken by following proportioning: Mahonia fortunei (Lindl.) Fedde 50g, Caulis Seu Folium Lespedezae Bicoloris 40g, Radix Zanthoxyli 25g, Fructus Kochiae 20g, being crushed to granular size is that after 100 orders, mixing loads the extraction column (abstraction instrument is purchased from Jinan A Erwa Instrument Ltd.) being placed in 150 DEG C of calorstats;
(2) under the constant-pressure conditions of 7.0MPa, pump into ultra-pure water by infusion pump by the ratio of solvent of 0.2mL/mg in extraction column, flow velocity is 1.0mL/min, collects extracting solution with stop valve simultaneously;
(3), after 35min, the extracting solution of collection is placed in 60 DEG C of baking ovens (Dongguan City Jian Qiao testing equipment company limited) and dries, obtain defying age plant extract compositions of the present invention.
Comparative example 3
(1) raw material is taken by following proportioning: Mahonia fortunei (Lindl.) Fedde 50g, Caulis Seu Folium Lespedezae Bicoloris 40g, Radix Zanthoxyli 25g, being crushed to granular size is that after 100 orders, mixing loads the extraction column (abstraction instrument is purchased from Jinan A Erwa Instrument Ltd.) being placed in 150 DEG C of calorstats;
(2) under the constant-pressure conditions of 7.0MPa, pump into ultra-pure water by infusion pump by the ratio of solvent of 0.2mL/mg in extraction column, flow velocity is 1.0mL/min, collects extracting solution with stop valve simultaneously;
(3), after 35min, the extracting solution of collection is placed in 60 DEG C of baking ovens (Dongguan City Jian Qiao testing equipment company limited) and dries, obtain defying age plant extract compositions of the present invention.
Containing and not containing the preparation of defying age plant extract compositions facial film, wherein embodiment 4-8,9, the plant extract compositions of 10 tool senile-resistant efficacies is respectively embodiment 2,1,3 gained; In comparative example 11-13, the plant extract compositions of tool senile-resistant efficacy is respectively comparative example 1,2,3 gained.
The formula of table 1 embodiment 4-10 defying age plant extract compositions facial film
Table 2 comparative example 4-11 contains and does not contain the formula of defying age plant extract compositions facial film
As shown in table 1 and 2, the preparation process of formula facial film is:
(1) be added to by A in emulsifying pot and be heated to 85 DEG C of insulation 30min and stir, make each material dissolution complete, the carbomer wherein in A phase is sprinkled under the condition of low speed homogenizing;
(2) less than 45 DEG C are cooled to after adding B phase stirring and dissolving;
(3) add C phase to stir;
(4) add the D phase of having dissolved in advance and E phase, stir and obtain the present invention containing defying age plant extract compositions facial film.
Above embodiment and the defying age plant extract compositions described in comparative example are all through stability test, to expect body respectively-22 DEG C, 6 DEG C, room temperature, continuous circulation 5 times under 45 DEG C of conditions, place 13 weeks under illumination condition, respectively expect that the color of body, abnormal smells from the patient and form all keep stable.
Facial film prepared in above embodiment and comparative example all through cutaneous safety test, confirms skin non-stimulated, can not cause irritated grade for untoward reaction, can feel at ease to use.
The anti-aging effects of assay 4-10 embodiment and the facial film prepared by 4-11 comparative example, wherein said anti-aging effects, for improving skin shine, eliminates microgroove, moistening skin.Crowd on probation is divided into 15 groups, often organizes 20 people, tested crowd's random packet, and product composition is not understood, get rid of the impact that psychological factor is evaluated Total Product.The same area scope that 15 groups of experimenters are often later than cheek pastes anti-ageing face mask in embodiment 4-10 and comparative example 4-11 respectively, try out continuously and after 50 days, facial film effect is evaluated, anti-aging effects is evaluated as Three Estate, be respectively: DeGrain (0 ~ 3 point), effect general (4 ~ 6 points), Be very effective (7 ~ 10 points), defying age resultant effect evaluation result is in table 3 and table 4.
Table 3 each embodiment facial film anti-aging effects Score Lists
Table 4 each comparative example facial film anti-aging effects Score Lists
The DE of tested crowd's cheek skin of 4 kinds of defying age plant extract compositions facial films of the present invention is added with from embodiment and the known use of comparative example 4-8, glossiness, wettability is obviously better than using the cheek not adding the tested crowd of defying age plant extract compositions facial film, and the anti-ageing effect score of embodiment 5-7 is all higher than embodiment 4, the anti-ageing effect score of 8, the better percentage-proportion interval that 4 kinds of defying age plant extract compositionss of the present invention account for facial film gross weight is as can be seen here 6.00%-20.00%, along with the anti-ageing effect of increase of defying age plant extract compositions percentage ratio also strengthens gradually within the scope of this.The anti-ageing effect of embodiment 6 with embodiment 9,10 is contrasted simultaneously, find that the score of anti-ageing the proportion by subtraction embodiment 9,10 of embodiment 6 is high, show under 4 kinds of defying age plant extract compositionss of the present invention add the same condition of percentage ratio in facial film, the anti-ageing best results of the defying age plant extract compositions using embodiment 2 obtained.The anti-ageing effect of comparative example 7 and comparative example 9-11 in addition, find to be added to by a kind of, two or three plant extract in plant of the present invention separately anti-ageing effect in facial film all lower than 6 points, all lower than the anti-ageing effect of Four Plants extract being added in facial film (whole more than 7 points, the remarkable anti-ageing effect of tool), and the anti-ageing effect of increase along with plant extract species within the scope of 4 kind of plant of the present invention also strengthens gradually, there is synergism between each defying age plant extract provided by the invention as can be seen here.
Above embodiment is only several embodiments of the present invention, but the present invention is not limited thereto.Based on the embodiment in the present invention, other embodiments all that those of ordinary skill in the art obtain under the prerequisite not making any creative work, all belong to the scope that the present invention protects.
Claims (7)
1. an antidotal plant extract compositions, is characterized in that, said composition comprises the extract of following weight part ratio raw material: Mahonia fortunei (Lindl.) Fedde 40-50 part, Caulis Seu Folium Lespedezae Bicoloris 30-40 part, Radix Zanthoxyli 15-25 part, Fructus Kochiae 10-20 part.
2. the antidotal plant extract compositions of one according to claim 1, is characterized in that, said composition comprises the extract of following weight part ratio raw material: Mahonia fortunei (Lindl.) Fedde 45 parts, Caulis Seu Folium Lespedezae Bicoloris 35 parts, Radix Zanthoxyli 20 parts, the Fructus Kochiae 15 parts.
3. the preparation method of a kind of defying age plant extract compositions according to claim 1 and 2, is characterized in that, the preparation method of described defying age plant extract compositions comprises the following steps:
(1) take raw material by weight, being crushed to granular size is that after 80-100 order, mixing loads the extraction column being placed in 135-150 DEG C of calorstat;
(2) under the constant-pressure conditions of 5.5-7MPa, pump into ultra-pure water by infusion pump by the ratio of solvent of 0.1-0.2mL/mg in extraction column, flow velocity is 0.8-1.0mL/min, collects extracting solution with stop valve simultaneously;
(3) after 25-35min, the extracting solution of collection is placed in 60 DEG C of baking ovens and dries, obtain defying age plant extract compositions of the present invention.
4. the application of a kind of defying age plant extract compositions in cosmetics according to any one of claim 1-3.
5. application according to claim 4, is characterized in that, described defying age plant extract compositions accounts for the 4.00%-30.00% of described cosmetics gross weight.
6. application according to claim 5, is characterized in that, described defying age plant extract compositions accounts for the 6.00%-20.00% of described cosmetics gross weight.
7. a defying age plant extract compositions facial film, is characterized in that, described defying age plant extract compositions facial film comprises the component of following percentage by weight:
Hydroxyethyl-cellulose: 0.04-0.08wt%,
Hyaluronate sodium: 0.04-0.06wt%,
Carbomer: 0.04-0.06wt%,
Glycerol: 5.00-9.00wt%,
Defying age plant extract compositions: 4.00-30.00wt% described in any one of claim 1-3,
Butanediol: 2.50-5.80wt%,
Betanin: 1.80-4.30wt%,
Jojoba butter (water): 0.04-0.05wt%,
Methyl hydroxybenzoate: 0.09-0.12wt%,
Triethanolamine: 0.04-0.06wt%,
The mixture of Fructus Hordei Germinatus oligose glucoside and hydrogenated starch hydrolysate 1:1: 1.43-1.75wt%,
Glycerol polymethacrylates, the mixture of propylene glycol and Gantrez AN-119 1:1:1: 2.00-4.00wt%,
The mixture of diazolidinyl urea and iodine propilolic alcohol butyl mephenesin Carbamate 1:1: 0.14-0.31wt%,
The mixture of Euglena gracilis polysaccharide and hydrolytic collagen 1:1: 0.04-0.06wt%,
Deionized water: 44.35-82.81wt%.
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| CN106821792A (en) * | 2017-03-27 | 2017-06-13 | 佛山市汇汾化妆品科技有限公司 | A kind of cleawhite pack |
| CN107569412A (en) * | 2017-08-16 | 2018-01-12 | 佛山实瑞先导材料研究院（普通合伙） | A kind of antioxidant and its application |
| CN108309882A (en) * | 2018-04-03 | 2018-07-24 | 翟艳威 | A kind of anti-aging plant extract composition and its application in cosmetics |
| CN108272712A (en) * | 2018-04-27 | 2018-07-13 | 孙瑞悒 | A kind of anti-aging plant extract composition and its application in cosmetics |
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