CN105496938A - Alpha-bisabolol skin lotion - Google Patents
Alpha-bisabolol skin lotion Download PDFInfo
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- CN105496938A CN105496938A CN201511007896.7A CN201511007896A CN105496938A CN 105496938 A CN105496938 A CN 105496938A CN 201511007896 A CN201511007896 A CN 201511007896A CN 105496938 A CN105496938 A CN 105496938A
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- bisabolol
- skin
- extract
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
- A61K8/553—Phospholipids, e.g. lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
Abstract
The invention discloses an alpha-bisabolol skin lotion. The alpha-bisabolol skin lotion is technically characterized by comprising the following components in parts by weight according to a formula: 10 to 14 parts of alpha-bisabolol, 8 to 10 parts of hydrogenated lecithin, 7 to 11 parts of saccharomyces ferment extract filtrate, 0.5 to 1 parts of daisy flower extract, 2 to 4 parts of lactobacillus/soybean ferment extract, 1 to 2 parts of grease-enrich agent, 3 to 4 parts of lotion, 1.5 to 3 parts of collagen, and 150 to 160 parts of glycerinum. The alpha-bisabolol skin lotion has the advantages that the alpha-bisabolol, the hydrogenated lecithin, the saccharomyces ferment extract filtrate, the daisy flower extract, and the lactobacillus/soybean ferment extract are cooperated to use, so that the good moisturizing, nourishing, anti-aging and firming effects are realized; by adding the hydrogenated lecithin, a nano-liposome can be prepared, and can coat hydrophilic components, so that the oil phase is more affined.
Description
Technical field
The present invention relates to a kind of skin care item, more particularly, it relates to a kind of α-bisabolol skin care liquid.
Background technology
Although skin aging is the natural physiological phenomenon of human body, environmental factors can aggravate this phenomenon, and female skin is especially true.If add the anti-ageing material that some have no side effect in cosmetics, skin care item, can the aging of delaying skin.In addition, skin allergy is common dermatosis, and especially cosmetic allergic contact dermatitis is the problem that many women and special occupation person encounter, and comprising: lipstick causes reddened and swollen lips, pain, scalp erythema, vesicle that hair dye causes, the pruritus that sunscreen cream, anti-freckle agent cause, pain and pigmentation.Allergic human population's skin sensitivity, smears and seems simple cosmetics and also there will be untoward reaction.Common are lipstick, hair dye etc., namely occur after using that skin is red, swollen, hot, itch, bitterly, the anaphylaxis problem such as to get blister, not only can not find beautiful sensation, embarrassment but occurs often.Suppressing and opposing skin allergy, is all very important problem from skin physiology and medical science and angle of improving looks.The method treatment of control traditional at present, as hormones, antihistaminic, although anti-inflammatory drugs treatment can make the problem of skin allergy and symptom be eased and treat within the regular hour, if but improper use, probably increase the weight of the state of an illness of skin, even can cause the irremediable pathological changes of skin.Therefore for how to suppress skin allergy problem to be very worth research safely and effectively.
, there is effective defying age, antianaphylactic material in research display, cosmetics, skin care item or the medicine that it can be utilized to make have defying age or anti-allergic effects in many natural plant extracts.Natural plants or its extract comprise: Radix Hamamelidis Mollis, Proflavanol, blueberry extract, Semen Ginkgo extrac, camomile extract, Fructus Crataegi extract, Radix Glycyrrhizae extract liquid and glycyrrhizic acid, Aloe gel, azulene, Bisabolol, neutral red bisabolol, Radix Astragali extract, honeysuckle extract, Flos Chrysanthemi Indici extract, Radix Isatidis elite, Cordyceps, Fructus actinidiae chinensis essence, Fructus Rosae Normalis extract, Calendula arvensis L. extract, yellow spring flower extract, Garden lavender essence, Sargassum essence, Radix Ophiopogonis, Semen Coicis, jasmine grass, favus skin, Ganoderma elite, green tea extract, Poria, Radix Scutellariae etc.But single active ingredient is often difficult to reach desirable effect.
Application number be 200880006159.7 PCT patent discloses the present invention relates to and a kind ofly comprise the compositions of α-bisabolol as the improvement skin of active component.α-bisabolol carrys out the synthesis of check melanin by the activity of tryrosinase in T suppression cell, and compared to the arbutin being used as existing skin whitener, it has larger skin lightening effects as active component.In addition, α-bisabolol also demonstrates on a molecular scale to the inhibitory action of collagenase activity and the facilitation to collagenous biological synthesis, has fabulous effect to improving wrinkle of skin.Meanwhile, α-bisabolol shows and promotes or alopecia prevention the improvement effect of UV-induced skin injury and skin growth.Therefore, α-bisabolol has fabulous improvement effect to skin.In addition, α-bisabolol has fabulous obesity and antioxidant effect.Compositions of the present invention does not have cytotoxicity and side effect, cosmetics, medicine and food compositions can be applied to safely, but said composition is only using α-bisabolol as active component, do not add the nutrient substance required for other skins, there is no follow-up nutrient for by the patched skin of α-bisabolol, be unfavorable for the reparative regeneration damaging rear skin.
The above-mentioned skin-protection product function containing α-bisabolol is all comparatively single, only can play antioxidation, repairs the effect of skin injury, cannot play further nourishing effect to skin.
Summary of the invention
For the deficiency that prior art exists, the object of the present invention is to provide a kind of α-bisabolol skin care liquid containing multiple nutrients material.
For achieving the above object, the invention provides following technical scheme: a kind of α-bisabolol skin care liquid, in this formula, each component is designated as by weight
α-bisabolol 10 ~ 14 parts
Hydrolecithin 8 ~ 10 parts
Yeast fermentation Product filtrate 7 ~ 11 parts
Daisy extract 0.5 ~ 1 part
Lactobacillus/fermented soybean product extract 2 ~ 4 parts
Compose fat agent 1 ~ 2 part
Wetting agent 3 ~ 4 parts
Glycerol 150 ~ 160 parts.
Wherein, using α-bisabolol as most basic skin protection material, α-bisabolol has extremely strong skin repair and antiallergic performance, easy damaged type skin is had and well repairs and maintenance effect, yeast will the wherein extracting such as protein, nucleic acid, vitamin after breaking cellular wall, then through the pale yellow powder being rich in the active skull cap components such as micromolecular aminoacid, peptide, nucleotide, vitamin of biological enzymolysis.Wherein amino acid content more than 30%, total protein more than 50%, nucleotide more than 10%, in cosmetics, there is moisturizing, compose effects such as living, aminoacid is the main component of natural Moisture factor (NMF) in keratodermatitis, easily be absorbed by the skin, aging epidermis is made to recover elasticity, delay skin aging, Daisy extract, there is antiallergic, irritation, the effect of skin care, lactobacillus/fermented soybean product extract is also containing abundant aminoacid, coordinate yeast fermentation Product filtrate and Daisy extract can nourishes rough skin well, simultaneously lactobacillus/fermented soybean product extract can also at the stable overlay film of skin surface generating structure, be conducive to the fixing of nutrient substance, thus the lasting nourishing achieved skin, nucleic acid and nucleotide are the central genetic materials of human body, have and enhance metabolism, improve the effects such as protein synthesis speed, strengthen immune function, enhance SOD activity, improve skin antiradical activities.In addition, the nutrients such as vitamin a small amount of in product and mineral can also provide sufficient nutrition for skin, and the existence of composing fat agent and wetting agent is then to improve humidity of skin, and skin is more added water profit; Adding hydrolecithin is then for the preparation of nanometer liposome, and nanometer liposome can wrap hydrophilic composition and make it more affine oil phase.
Preferably, the agent of described tax fat is one or more in the macrogol ester of isopropyl myristate and glyceryl Oleum Cocois.
Isopropyl myristate is non-fat emollient, is very easily absorbed by the skin.Be one of component of semisolid matrix, also can be used as the solvent of many materials in local administration preparation.It is applied to various topical formulations and cosmetics, comprises bath oil, cosmetics, hair care armor product, facial cream, lotion, lip-stick, shaving cream, emollient, deodorizer, ear's suspensoid, vaginal cream.Such as, isopropyl myristate is a kind of self emulsifying composition in a certain cold cream prescription, and this cold cream prescription can be used as the substrate of many medicines and dermatologic thing; In cosmetics, it also has application in the stable mixed liquor of water and glycerol.Isopropyl myristate can be used as the penetration enhancers in transdermal absorption formulation, can combine use with treatment ultrasound wave and iontophoresis.Isopropyl myristate can be used as the main component of oil phase in water-oleogel slow release breast (water-oilgelprolonged-releaseemulsion); therefore can as a kind of tax fat agent of function admirable; coconut oil glyceride polarity is very weak; in skin ductility and absorbability good; fully can extend at skin surface; form the protecting film of skin, one deck oil phase thin film can be formed at skin surface well as the agent of tax fat, thus good protected effect is played to skin.
Preferably, described wetting agent is the compositions of one or more and protein-Si polymeric protein in glycerol and sorbitol.
Glycerol and sorbitol are all conventional and wetting agent of good performance, protein-Si polymeric protein is nature moisturizing factor, nature moisturizing factor can be combined with water in horny layer, and by regulating, storing moisture content to reach the effect keeping water content between horn cell, make skin naturally present water profit state.If nature moisturizing factor shortage or unsound, the colour of skin just can be caused dim heavy, produce microgroove and also become dry, responsive.Within 24 hours, continue intensive activating skin nature moisturizing factor (N.M.F.), the restorative water suction of skin, lock water mechanism can be helped, there is provided skin long-acting moistening effect continuously, by conventional wetting agent and nature moisturizing factor with the use of can be that skin keeps long-acting lasting moistening effect.
Compared with prior art the present invention has following advantage: wherein, using α-bisabolol as most basic skin protection material, α-bisabolol has extremely strong skin repair and antiallergic performance, easy damaged type skin is had and well repairs and maintenance effect, yeast will the wherein extracting such as protein, nucleic acid, vitamin after breaking cellular wall, then through the pale yellow powder being rich in the active skull cap components such as micromolecular aminoacid, peptide, nucleotide, vitamin of biological enzymolysis.Wherein amino acid content more than 30%, total protein more than 50%, nucleotide more than 10%, in cosmetics, there is moisturizing, compose effects such as living, aminoacid is the main component of natural Moisture factor (NMF) in keratodermatitis, easily be absorbed by the skin, aging epidermis is made to recover elasticity, delay skin aging, Daisy extract, there is antiallergic, irritation, the effect of skin care, lactobacillus/fermented soybean product extract is also containing abundant aminoacid, coordinate yeast fermentation Product filtrate and Daisy extract can nourishes rough skin well, simultaneously lactobacillus/fermented soybean product extract can also at the stable overlay film of skin surface generating structure, be conducive to the fixing of nutrient substance, thus the lasting nourishing achieved skin, nucleic acid and nucleotide are the central genetic materials of human body, have and enhance metabolism, improve the effects such as protein synthesis speed, strengthen immune function, enhance SOD activity, improve skin antiradical activities.In addition, the nutrients such as vitamin a small amount of in product and mineral can also provide sufficient nutrition for skin, and the existence of composing fat agent and wetting agent is then to improve humidity of skin, and skin is more added water profit; Adding hydrolecithin is then for the preparation of nanometer liposome, and nanometer liposome can wrap hydrophilic composition and make it more affine oil phase.
Detailed description of the invention
Embodiment 1
α-bisabolol 10 parts
Hydrolecithin 8 parts
Yeast fermentation Product filtrate 7 parts
Daisy extract 0.5 part
Lactobacillus/fermented soybean product extract 2 parts
The Polyethylene Glycol of glyceryl Oleum Cocois 1 part
Glycerol 2 parts
Protein-Si polymeric protein 1 part
1 part, NTx albumen
V collagen type 0.5 part
Glycerol 150 parts
Embodiment 2
α-bisabolol 14 parts
Hydrolecithin 10 parts
Yeast fermentation Product filtrate 11 parts
Daisy extract 1 part
Lactobacillus/fermented soybean product extract 4 parts
Isopropyl myristate 2 parts
Sorbitol 2 parts
Protein-Si polymeric protein 2 parts
2 parts, NTx albumen
V collagen type 1 part
Glycerol 160 parts
Embodiment 3
α-bisabolol 12.2 parts
Hydrolecithin 9 parts
Yeast fermentation Product filtrate 9 parts
Daisy extract 0.7 part
Lactobacillus/fermented soybean product extract 3 parts
Isopropyl myristate 1.2 parts
The macrogol ester of glyceryl Oleum Cocois 0.5 part
Glycerol 1.2 parts
Sorbitol 1.5 parts
Protein-Si polymeric protein 1 part
1.6 parts, NTx albumen
V collagen type 1.1 parts
Glycerol 156 parts
Comparative example
α-bisabolol 12.2 parts
Yeast fermentation Product filtrate 8 parts
Daisy extract 0.7 part
Lactobacillus/fermented soybean product extract 3 parts
Isopropyl myristate 1.2 parts
The macrogol ester of glyceryl Oleum Cocois 0.5 part
Glycerol 1.2 parts
Sorbitol 1.5 parts
Protein-Si polymeric protein 1 part
1.6 parts, NTx albumen
V collagen type 1.1 parts
Glycerol 156 parts
The above is only the preferred embodiment of the present invention, protection scope of the present invention be not only confined to above-described embodiment, and all technical schemes belonged under thinking of the present invention all belong to protection scope of the present invention.It should be pointed out that for those skilled in the art, some improvements and modifications without departing from the principles of the present invention, these improvements and modifications also should be considered as protection scope of the present invention.
Properties of product are tested
Use the hairless mouse of ultraviolet to identical physique and health status to carry out ultraviolet solar simulated to burn process, then respectively the wound surface of mice is smeared with the product obtained according to three groups of embodiments respectively, observe the healing time of mice, observe and find, healing time sorts as embodiment 1> embodiment 3> embodiment 2> comparative example with this from long to short, as can be seen here, the addition of α-bisabolol is directly proportional to the wound healing effect of this formulation product, simultaneously hydrolecithin is added to this formula as the raw material of nanometer liposome and effectively can improves the absorbability of skin to α-bisabolol.
Claims (3)
1. α-bisabolol skin care liquid, is characterized in that: in this formula, each component is designated as by weight
α-bisabolol 10 ~ 14 parts
Hydrolecithin 8 ~ 10 parts
Yeast fermentation Product filtrate 7 ~ 11 parts
Daisy extract 0.5 ~ 1 part
Lactobacillus/fermented soybean product extract 2 ~ 4 parts
Compose fat agent 1 ~ 2 part
Wetting agent 3 ~ 4 parts
Glycerol 150 ~ 160 parts.
2. α according to claim 1-bisabolol skin care liquid, is characterized in that: the agent of described tax fat is one or more in the macrogol ester of isopropyl myristate and glyceryl Oleum Cocois.
3. α according to claim 1-bisabolol skin care liquid, is characterized in that: described wetting agent is the compositions of one or more and protein-Si polymeric protein in glycerol and sorbitol.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201511007896.7A CN105496938B (en) | 2015-12-29 | 2015-12-29 | α-bisabolol shin moisturizer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201511007896.7A CN105496938B (en) | 2015-12-29 | 2015-12-29 | α-bisabolol shin moisturizer |
Publications (2)
| Publication Number | Publication Date |
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| CN105496938A true CN105496938A (en) | 2016-04-20 |
| CN105496938B CN105496938B (en) | 2019-01-01 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201511007896.7A Active CN105496938B (en) | 2015-12-29 | 2015-12-29 | α-bisabolol shin moisturizer |
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| CN (1) | CN105496938B (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107519089A (en) * | 2017-09-07 | 2017-12-29 | 蝶柔化妆品(浙江)有限公司 | A kind of honeycomb hyaluronic acid stoste |
| CN107789303A (en) * | 2016-08-30 | 2018-03-13 | 陈磊 | A kind of aerolite facial mask and its manufacture craft |
| CN107789237A (en) * | 2016-08-30 | 2018-03-13 | 陈磊 | A kind of aerolite face cream and its manufacture craft |
| CN109793753A (en) * | 2017-11-17 | 2019-05-24 | 成都澳立生态科技发展有限公司 | A kind of Derma-Guard of antibiotic skin-care |
| CN110522655A (en) * | 2019-08-14 | 2019-12-03 | 天津科技大学 | A kind of active peptides milk matrix lipid body essence lotion and preparation method thereof with blue-opalescent and Tyndall effect |
| CN114504513A (en) * | 2022-01-07 | 2022-05-17 | 北京理工大学重庆创新中心 | Composite probiotic matrine coconut oil liposome and preparation method and application thereof |
| CN115554222A (en) * | 2021-07-01 | 2023-01-03 | 北京道康国际生物科技有限公司 | Skin care product with whitening and spot-fading functions as well as preparation method and application thereof |
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| CN104042559A (en) * | 2014-06-30 | 2014-09-17 | 广州赋雅化妆品有限公司 | Natural composition and natural cosmetic both having whitening and spot-lightening effects |
| CN104546589A (en) * | 2014-12-12 | 2015-04-29 | 无限极（中国）有限公司 | Skin moisturizer with components from natural food and application of skin moisturizer |
| CN105055296A (en) * | 2015-08-21 | 2015-11-18 | 广州透真生物科技有限公司 | Skin care product composition containing saccharomycetes fermentation product filter liquor |
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2015
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107789303A (en) * | 2016-08-30 | 2018-03-13 | 陈磊 | A kind of aerolite facial mask and its manufacture craft |
| CN107789237A (en) * | 2016-08-30 | 2018-03-13 | 陈磊 | A kind of aerolite face cream and its manufacture craft |
| CN107519089A (en) * | 2017-09-07 | 2017-12-29 | 蝶柔化妆品(浙江)有限公司 | A kind of honeycomb hyaluronic acid stoste |
| CN109793753A (en) * | 2017-11-17 | 2019-05-24 | 成都澳立生态科技发展有限公司 | A kind of Derma-Guard of antibiotic skin-care |
| CN110522655A (en) * | 2019-08-14 | 2019-12-03 | 天津科技大学 | A kind of active peptides milk matrix lipid body essence lotion and preparation method thereof with blue-opalescent and Tyndall effect |
| CN110522655B (en) * | 2019-08-14 | 2022-04-12 | 天津科技大学 | Active polypeptide milk matrix liposome essence water with blue opalescence and Tyndall effect and preparation method thereof |
| CN115554222A (en) * | 2021-07-01 | 2023-01-03 | 北京道康国际生物科技有限公司 | Skin care product with whitening and spot-fading functions as well as preparation method and application thereof |
| CN114504513A (en) * | 2022-01-07 | 2022-05-17 | 北京理工大学重庆创新中心 | Composite probiotic matrine coconut oil liposome and preparation method and application thereof |
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| CN105496938B (en) | 2019-01-01 |
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