CN105456053A - Permanent hair dye prepared from dye and enzyme sourced from natural plants - Google Patents
Permanent hair dye prepared from dye and enzyme sourced from natural plants Download PDFInfo
- Publication number
- CN105456053A CN105456053A CN201510182835.8A CN201510182835A CN105456053A CN 105456053 A CN105456053 A CN 105456053A CN 201510182835 A CN201510182835 A CN 201510182835A CN 105456053 A CN105456053 A CN 105456053A
- Authority
- CN
- China
- Prior art keywords
- dose
- enzyme
- hair
- deionized water
- glucosidase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000975 dye Substances 0.000 title claims abstract description 42
- 102000004190 Enzymes Human genes 0.000 title claims abstract description 41
- 108090000790 Enzymes Proteins 0.000 title claims abstract description 41
- 239000001024 permanent hair color Substances 0.000 title abstract description 7
- 210000004209 hair Anatomy 0.000 claims abstract description 75
- 230000000694 effects Effects 0.000 claims abstract description 25
- 238000004043 dyeing Methods 0.000 claims abstract description 24
- 238000000034 method Methods 0.000 claims abstract description 22
- 238000001694 spray drying Methods 0.000 claims abstract description 13
- 239000000843 powder Substances 0.000 claims abstract description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 64
- 239000008367 deionised water Substances 0.000 claims description 50
- 229910021641 deionized water Inorganic materials 0.000 claims description 50
- 102000006995 beta-Glucosidase Human genes 0.000 claims description 38
- 108010047754 beta-Glucosidase Proteins 0.000 claims description 38
- RJWJHRPNHPHBRN-FKVJWERZSA-N aucubin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@H]1[C@@H]2C(CO)=C[C@@H](O)[C@@H]2C=CO1 RJWJHRPNHPHBRN-FKVJWERZSA-N 0.000 claims description 35
- UTDFQMAXCUGNJR-UHFFFAOYSA-N aucubin Natural products OCC1OC(Oc2ccoc2C3C(O)CCC3O)C(O)C(O)C1O UTDFQMAXCUGNJR-UHFFFAOYSA-N 0.000 claims description 35
- 239000007788 liquid Substances 0.000 claims description 34
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 30
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 claims description 30
- 239000000118 hair dye Substances 0.000 claims description 29
- JIGUQPWFLRLWPJ-UHFFFAOYSA-N Ethyl acrylate Chemical compound CCOC(=O)C=C JIGUQPWFLRLWPJ-UHFFFAOYSA-N 0.000 claims description 25
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 claims description 25
- 229920001577 copolymer Polymers 0.000 claims description 25
- PNJWIWWMYCMZRO-UHFFFAOYSA-N pent‐4‐en‐2‐one Natural products CC(=O)CC=C PNJWIWWMYCMZRO-UHFFFAOYSA-N 0.000 claims description 25
- 230000001804 emulsifying effect Effects 0.000 claims description 24
- GEHJYWRUCIMESM-UHFFFAOYSA-L sodium sulfite Chemical compound [Na+].[Na+].[O-]S([O-])=O GEHJYWRUCIMESM-UHFFFAOYSA-L 0.000 claims description 20
- 229940008099 dimethicone Drugs 0.000 claims description 18
- 239000004205 dimethyl polysiloxane Substances 0.000 claims description 18
- 235000013870 dimethyl polysiloxane Nutrition 0.000 claims description 18
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims description 18
- 229920000642 polymer Polymers 0.000 claims description 17
- 238000002360 preparation method Methods 0.000 claims description 17
- 239000004902 Softening Agent Substances 0.000 claims description 16
- 238000009413 insulation Methods 0.000 claims description 16
- 239000007787 solid Substances 0.000 claims description 16
- 239000006185 dispersion Substances 0.000 claims description 15
- 239000000203 mixture Substances 0.000 claims description 11
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 claims description 10
- 239000004354 Hydroxyethyl cellulose Substances 0.000 claims description 10
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 claims description 10
- DOOTYTYQINUNNV-UHFFFAOYSA-N Triethyl citrate Chemical compound CCOC(=O)CC(O)(C(=O)OCC)CC(=O)OCC DOOTYTYQINUNNV-UHFFFAOYSA-N 0.000 claims description 10
- 229940071826 hydroxyethyl cellulose Drugs 0.000 claims description 10
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 claims description 10
- 238000002156 mixing Methods 0.000 claims description 10
- 239000002304 perfume Substances 0.000 claims description 10
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 claims description 10
- 229920000053 polysorbate 80 Polymers 0.000 claims description 10
- 235000010265 sodium sulphite Nutrition 0.000 claims description 10
- 239000000725 suspension Substances 0.000 claims description 10
- 239000001069 triethyl citrate Substances 0.000 claims description 10
- VMYFZRTXGLUXMZ-UHFFFAOYSA-N triethyl citrate Natural products CCOC(=O)C(O)(C(=O)OCC)C(=O)OCC VMYFZRTXGLUXMZ-UHFFFAOYSA-N 0.000 claims description 10
- 235000013769 triethyl citrate Nutrition 0.000 claims description 10
- 230000002421 anti-septic effect Effects 0.000 claims description 8
- 238000007599 discharging Methods 0.000 claims description 8
- 239000000839 emulsion Substances 0.000 claims description 8
- 239000006260 foam Substances 0.000 claims description 8
- 239000000463 material Substances 0.000 claims description 8
- 108700019599 monomethylolglycine Proteins 0.000 claims description 8
- 229940101011 sodium hydroxymethylglycinate Drugs 0.000 claims description 8
- CITBNDNUEPMTFC-UHFFFAOYSA-M sodium;2-(hydroxymethylamino)acetate Chemical compound [Na+].OCNCC([O-])=O CITBNDNUEPMTFC-UHFFFAOYSA-M 0.000 claims description 8
- 238000003756 stirring Methods 0.000 claims description 8
- 230000008961 swelling Effects 0.000 claims description 8
- 238000005406 washing Methods 0.000 claims description 8
- 206010049865 Achromotrichia acquired Diseases 0.000 claims description 6
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 6
- 238000004519 manufacturing process Methods 0.000 claims description 5
- 101710099628 Beta-glucosidase 1 Proteins 0.000 claims description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 4
- 239000000284 extract Substances 0.000 claims description 4
- 239000002674 ointment Substances 0.000 claims description 3
- 229940100555 2-methyl-4-isothiazolin-3-one Drugs 0.000 claims description 2
- BEGLCMHJXHIJLR-UHFFFAOYSA-N methylisothiazolinone Chemical compound CN1SC=CC1=O BEGLCMHJXHIJLR-UHFFFAOYSA-N 0.000 claims description 2
- 238000005516 engineering process Methods 0.000 abstract description 7
- 239000003795 chemical substances by application Substances 0.000 abstract description 5
- 239000000835 fiber Substances 0.000 abstract description 5
- 239000000126 substance Substances 0.000 abstract description 5
- 230000007613 environmental effect Effects 0.000 abstract description 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract description 2
- 239000002932 luster Substances 0.000 abstract description 2
- 239000001301 oxygen Substances 0.000 abstract description 2
- 229910052760 oxygen Inorganic materials 0.000 abstract description 2
- 231100000614 poison Toxicity 0.000 abstract description 2
- PAYRUJLWNCNPSJ-UHFFFAOYSA-N Aniline Chemical compound NC1=CC=CC=C1 PAYRUJLWNCNPSJ-UHFFFAOYSA-N 0.000 abstract 2
- 239000000412 dendrimer Substances 0.000 abstract 1
- 229920000736 dendritic polymer Polymers 0.000 abstract 1
- 230000007794 irritation Effects 0.000 abstract 1
- 238000000710 polymer precipitation Methods 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 239000003440 toxic substance Substances 0.000 abstract 1
- 230000002255 enzymatic effect Effects 0.000 description 7
- 239000003094 microcapsule Substances 0.000 description 6
- 239000002537 cosmetic Substances 0.000 description 5
- 238000001556 precipitation Methods 0.000 description 5
- 239000000047 product Substances 0.000 description 5
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 4
- 239000003814 drug Substances 0.000 description 4
- 210000003491 skin Anatomy 0.000 description 4
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 3
- 230000001590 oxidative effect Effects 0.000 description 3
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
- WZUVPPKBWHMQCE-UHFFFAOYSA-N Haematoxylin Chemical compound C12=CC(O)=C(O)C=C2CC2(O)C1C1=CC=C(O)C(O)=C1OC2 WZUVPPKBWHMQCE-UHFFFAOYSA-N 0.000 description 2
- 244000208060 Lawsonia inermis Species 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 150000001448 anilines Chemical class 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 230000015556 catabolic process Effects 0.000 description 2
- 238000006731 degradation reaction Methods 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 238000005538 encapsulation Methods 0.000 description 2
- 230000003648 hair appearance Effects 0.000 description 2
- 230000008595 infiltration Effects 0.000 description 2
- 238000001764 infiltration Methods 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 231100000252 nontoxic Toxicity 0.000 description 2
- 230000003000 nontoxic effect Effects 0.000 description 2
- 230000001473 noxious effect Effects 0.000 description 2
- 239000002244 precipitate Substances 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 210000000582 semen Anatomy 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- BACWCXKATFIVFS-JQCXWYLXSA-N (1r,4ar,5s,7as)-7-(hydroxymethyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-1,5-diol Chemical compound C1=CO[C@@H](O)[C@@H]2C(CO)=C[C@@H](O)[C@@H]21 BACWCXKATFIVFS-JQCXWYLXSA-N 0.000 description 1
- 206010009866 Cold sweat Diseases 0.000 description 1
- 208000008454 Hyperhidrosis Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000007059 acute toxicity Effects 0.000 description 1
- 231100000403 acute toxicity Toxicity 0.000 description 1
- 235000001014 amino acid Nutrition 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 238000004040 coloring Methods 0.000 description 1
- 238000006482 condensation reaction Methods 0.000 description 1
- 238000002425 crystallisation Methods 0.000 description 1
- 230000008025 crystallization Effects 0.000 description 1
- 208000013219 diaphoresis Diseases 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 210000000981 epithelium Anatomy 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 230000037308 hair color Effects 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 238000010406 interfacial reaction Methods 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 229910021645 metal ion Inorganic materials 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 239000007800 oxidant agent Substances 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 239000003208 petroleum Substances 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 230000007096 poisonous effect Effects 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 239000013558 reference substance Substances 0.000 description 1
- 238000004007 reversed phase HPLC Methods 0.000 description 1
- 210000004761 scalp Anatomy 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 239000002453 shampoo Substances 0.000 description 1
- 150000003384 small molecules Chemical class 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
Landscapes
- Cosmetics (AREA)
Abstract
The invention relates to permanent hair dye prepared from dye and enzyme sourced from natural plants. The permanent hair dye is composed of a paste agent I with pH ranging from 6 to 10 and a powder agent II. The agent I and the agent II provide the dye and the enzyme respectively, dendritic polymer precipitation with the color from brown to black is generated after the agent I and the agent II are mixed, and hairs can be dyed to brown or black. The permanent hair dye is strong in adhesiveness with hair fibers, natural in color and luster and free of irritation to skin. A spray drying method microencapsulation technology is adopted by the agent II, the problems that due to the fact that the enzyme is prone to be affected by environmental factors such as light, heat, oxygen, humidity and pH value due to the active property of the enzyme, the stability is poorer, and the shelf life is short are effectively solved, and the prepared enzyme powder is good in functional property, stable to store and convenient to use. The permanent hair dye is free of aniline toxic substances and harmless to human bodies, substances which are toxic to the human bodies are not generated in the hair dyeing process, and the permanent hair dye is very safe and good in dyeing effect.
Description
Technical field
The invention belongs to hair dyeing cosmetic technical field, particularly a kind of Permanent Hair Dyeing Agent prepared by dyestuff and the enzyme of natural botanical source.
Background technology
Hair dyeing cosmetic refers to the chemical everyday articles that can change hair color.Hair dyeing is actually hair dye from the interfacial reactions such as the outermost contact moistening of hair epidermis, absorption, then arrived by the complex of cell membrane that hair epithelium and hair marrow make it produce to soak into, diffusing phenomenon, " polymerization " reaction is there is with situation difference, make hair generation effect hair change color, see Fig. 1.Different by the position of dyeing from hair dyeing mechanism, hair dye can be classified by shown in Fig. 2.Temporary, semipermanent and permanent three classes can be divided into by the firmness of dyeing; By the form of product, aqueous, emulsus, paste, powdery, shampoo type etc. can be divided into again several.General be all after having hair dyed color and luster be trapped in the persistency of time on hair and carry out classifying and determine its purposes.
Permanent Hair Dyeing Agent occupies 70 ~ 80% in whole hair dyeing cosmetic product, its effective ingredient can penetrate in the inner medula of hair and form stable larger dye molecule, be closed in hair fiber, thus play lasting hair dyeing effect, generally can keep 1 ~ 3 month.Mechanism can be sketched and be: small molecule dyes developer → infiltration hair quality is inner → through oxidizing → carry out condensation reaction with couplant to generate macromole dyestuff → be locked at hair quality inside → formation persistency to have hair dyed.
Permanent hair dye mostly is oxidized form hair dyeing cosmetic, generally is double-formulation, the hair dyeing I dose being main formation with developer and couplant and the II dose of composition formed with oxidant.During production preparation, two doses will separately be carried out, and during use, by two doses of mixing, repaste cloth infiltration hair and dye.Research confirms that oxidative hair dyes has certain infringement to scalp, and toxicity is large, and easily cause skin to produce the senses of discomfort such as redness, twinge, life-time service is cause cancer even.
How to develop safety, zest is low, hair dye that is that have no side effect causes people day by day attention, the hair dyed agent of exploitation natural botanical source active component is significant.China cosmetics expert also extensively studies black active component of dye such as Chinese medicine Galla Chinensis, Radix Polygoni Multiflori, hematoxylin, Semen Sesami Nigrum and Semen sojae atricolors, for exploitation botanical hair dye new product is laid a good foundation, the hair dye that current application is the most successfully mignonettetree, Henna powder is made, is specifically designed to the dyeing of brown hair.
The dyestuff of introduction of the present invention is the aucubin of natural botanical source, is one of effective ingredient of the Chinese crude drugs such as the Cortex Eucommiae, Herba Plantaginis, Radix Rehmanniae, is mainly the industries such as medicine, daily-use chemical industry and feedstuff and applies.Aucubin is white powder or crystallization, and molecular formula is C
15h
22o
9, molecular weight is 346.33.Fusing point is 181 DEG C, is dissolved in ethanol, is insoluble to ether, chloroform, benzene and petroleum ether, and acute toxicity pharmacological evaluation shows that it is almost nontoxic.
The glycosidic bond being extensively present in the aucubin in Chinese herbal medicine easily ruptures, can be decomposed by diluted acid and enzyme, generate aucubin aglycon, sugar and other catabolites, thus react with aminoacid and generate color products, if fresh Cortex Eucommiae endepidermis was white originally, after processing " diaphoresis ", namely become black, when Radix Scrophulariae is excavated, root bark is yellow-white, after dry in the sun, Intradermal is clamminess and becomes corvinus, and these phenomenons are all relevant with the degraded of aucubin.ChunInKoo etc. adopt reversed-phase HPLC to have studied pH value, ionic strength, metal ion to the impact of aucubin, find that aucubin can generate brown precipitate by fast degradation in strong acid.Research show aucubin itself can not with protein bound, but beta-glucosidase exist can with albumen covalent bond.Different according to its consumption, can generate the brown black dendritic that arrives and precipitate, this precipitation is strong with a fiber tack, and natural in color is non-stimulated to skin, belongs to permanent hair dyestuff.
The enzyme of introduction of the present invention is the beta-glucosidase of natural botanical source.Li Yang etc. find that the enzyme of separate sources is different to the Degradation of aucubin, and the activity of the beta-glucosidase in some seed class Chinese crude drug is high more than the activity of the beta-glucosidase reference substance obtained from fermentable.And beta-glucosidase enzymatic property is active, less stable, be vulnerable to the impact of the environmental factorss such as light, heat, oxygen, humidity and pH value.
Adopt spray drying method microcapsule technology, beta-glucosidase is allowed to be embedded in methacrylic acid and ethyl acrylate (1:1) aqueous copolymer dispersion (polymer content 30%), spray-driedly make microcapsule powder, reduce or avoid environmental factors on the impact of the stability of beta-glucosidase, obtained beta-glucosidase has good functional character, stable storage, easy to use, its situation being greater than 5.5 at pH can discharge beta-glucosidase fast, all has great practical significance to the storage of beta-glucosidase and application.The principle of spray drying method microcapsule technology can be understood as wall material and forms a kind of network structure, plays the effect of screening.Micromolecule thing is as water, and because volume is little, the effect through heat can successfully be shifted out, and the heartwood that molecular volume is larger is then stranded in net.In the curing process, although the temperature of hot-air may be very high, due to water rapid evaporation thus ensure that heartwood temperature is lower than 100 DEG C from wall material.Meanwhile, the time that atomizing particle is exposed in hot-air was no more than at most for tens seconds, so this method is also suitable for the micro encapsulation of heat-sensitive material.
Apply Permanent Hair Dyeing Agent prepared by above method and effectively can solve the more ubiquitous shortcomings of botanical hair dye, as hair dye composition is unstable, dye-uptake is not high, and dyeing time is long, and these problems directly affect the Color of natural hair dye.Hair dye of the present invention belongs to permanent brown, black hair dye, not containing phenyl amines noxious substance, harmless, and also can not produce the material poisonous to human body in hair dye, very safe, and Color is good.
Summary of the invention
The object of the present invention is to provide Permanent Hair Dyeing Agent prepared by a kind of dyestuff by natural botanical source and enzyme, the dyestuff of this hair dye is aucubin, enzyme is the beta-glucosidase adopting spray drying method microcapsule technology to prepare, the hair dye colouring nature prepared, hair dyeing effect is desirable, is Permanent Hair Dyeing Agent.
A kind of Permanent Hair Dyeing Agent prepared by dyestuff and the enzyme of natural botanical source of the present invention, is characterized in that it is made up of following I dose (unguentum, pH6 ~ 10), II dose (powder) two components:
(1) I dose comprises following component by weight percentage: aucubin 16 ~ 30%, hydroxyethyl-cellulose 3 ~ 6%, glycerol 2 ~ 4%, dimethicone 1 ~ 2%, soluble perfume 0.1 ~ 0.4%, antiseptic 0 ~ 0.3%, balance deionized water is supplied, and the potassium hydroxide with 10% adjusts pH to 6 ~ 10;
(2) II doses by beta-glucosidase 1 ~ 10%, sodium sulfite 0 ~ 0.1%, methacrylic acid and ethyl acrylate (1:1) aqueous copolymer dispersion (polymer content 30%) 50 ~ 60%, triethyl citrate 1 ~ 2%, mono stearate glyceryl ester 0.5 ~ 1%, tween 80 0.5 ~ 1.5%, balance deionized water is supplied, and the suspension made is spray-dried obtained.
The invention provides the manufacture method of above-mentioned hair dye:
The preparation method of (1) I dose is: with the hydroxyethyl-cellulose of deionized water swelling 3 ~ 6%, add 2 ~ 4% glycerol, 1 ~ 2% dimethicone, aucubin 16 ~ 30%, 0.1 ~ 0.4% soluble perfume, 0 ~ 0.3% antiseptic, balance deionized water is supplied, potassium hydroxide with 10% adjusts pH to 6 ~ 8, stirs 15 ~ 20min, discharging;
(2) II doses of preparation methoies are: the deionized water accounting for total amount of deionized water 45% is heated to 70 ~ 80 DEG C, add triethyl citrate 1 ~ 2%, mono stearate glyceryl ester 0.5 ~ 1%, tween 80 0.5 ~ 1.5%, emulsify at a high speed is sheared, the now solid content of emulsifying liquid about 15%, as foam too much can add dimethicone froth breaking in right amount, again the deionized water accounting for total amount of deionized water 25% is added in this emulsifying liquid, be stirred to room temperature, this emulsified mixed suspension liquid is poured into methacrylic acid and ethyl acrylate (1:1) aqueous copolymer dispersion (polymer content 30%) of 50 ~ 60%, moderate-speed mixer, again by advance with the beta-glucosidase 1 ~ 10% of deionized water dissolving accounting for total amount of deionized water 30%, enzyme liquid prepared by sodium sulfite 0 ~ 0.1% is poured methacrylic acid and ethyl acrylate (1:1) copolymer solution into and is stirred 20 ~ 50min(300 ~ 1000r/min, 30 ~ 45 DEG C), the now solid content of emulsifying liquid about 25%.This emulsion spray drying namely obtained II dose, spray-dired condition is: inlet temperature 80 ~ 180 DEG C, leaving air temp 50 ~ 120 DEG C.
Aucubin according to claim 1 and 2, beta-glucosidase are from plant material, adopt conventional extracting method to prepare, and preferential water or the alcohol of using extracts.In actual production, the commercial prod that aucubin, beta-glucosidase can extract from suppliers buying from plant material, for saving cost, the preferred purity 60 ~ 80% of aucubin, the optional thick enzyme of beta-glucosidase, specific activity of enzyme is 20 ~ 50U/mg preferably, more preferably 30 ~ 40U/mg.
Mass ratio 1:1 ~ the 1:10 of beta-glucosidase and aucubin in hair dye according to claim 1 and 2.
In hair dye according to claim 1 and 2, to be that poliosis can be dyed by 2 ~ 10U:1mg brown for the enzyme activity of beta-glucosidase and the mass ratio of aucubin; The mass ratio of the enzyme activity of beta-glucosidase and aucubin is needed to be that poliosis can be dyed black by 8 ~ 20U:1mg.
Antiseptic according to claim 1 is alkaline antiseptic Methylisothiazolinone or sodium hydroxy methyl glycinate, and use amount is respectively 0 ~ 0.01% or 0.2 ~ 0.4%.
Methacrylic acid according to claim 1 and 2 and ethyl acrylate (1:1) aqueous copolymer dispersion (polymer content 30%) can directly commodities purchased product as especially strange L30D-55; Or buy methacrylic acid and ethyl acrylate (1:1) copolymer, then be mixed with methacrylic acid and ethyl acrylate (1:1) aqueous copolymer dispersion (polymer content 30%) by 30% polymer content, 10%1mol/L sodium hydroxide solution, 60% deionized water.
The using method of above-mentioned hair dye is the invention provides: by I dose, II dose Homogeneous phase mixing according to claim 1 or 2,40 ~ 50 DEG C of insulation about 20 ~ 30min, use hairdressing to commonly use softening agent the hair scale sheet of hair epidermal area is opened simultaneously, softening agent is washed with water after 10 ~ 15min, then the mixture of I dose, II dose is spread upon on hair, 40 ~ 50 DEG C of insulation 30 ~ 60min, namely washing totally completes dyeing.
The present invention has following technique effect:
1. dyestuff of the present invention is the aucubin of natural botanical source, it is substantially to human non-toxic's evil, under beta-glucosidase effect can with albumen covalent bond, different according to beta-glucosidase enzyme dosage, can generate brown to black dendritic precipitation, this precipitation is strong with a fiber tack, natural in color, non-stimulated to skin, belong to impermeant dye;
2. the spray drying method microcapsule technology of beta-glucosidase employing of the present invention, this technology can make the stability of beta-glucosidase improve thus meet the shelf life requirement of hair dye, again because of its to be greater than the condition of 5.5 at pH under can discharge beta-glucosidase fast, beta-glucosidase is made to have good functional character, bin stability, ease of use;
3. the present invention is that a kind of dyestuff of natural botanical source and enzyme prepare Permanent Hair Dyeing Agent, not containing phenyl amines noxious substance, is made up of I dose (unguentum, pH6 ~ 10), II dose (powder) two components.After I dose, II dose Homogeneous phase mixing, in II dose by the beta-glucosidase of encapsulation under environment pH is greater than 5.5 conditions, discharge immediately because of microcapsules rupture, make in I dose aucubin degraded and with albumen covalent bond, generate brown to black dendritic precipitation, this precipitation is strong with a fiber tack, and natural in color is non-stimulated to skin;
4. the present invention prepares the hair dye of two kinds of colors by the different amounts of dyestuff of the same race and enzyme, and it is brown that the enzyme activity of beta-glucosidase and the mass ratio of aucubin are that poliosis can be dyed by 2 ~ 10U:1mg; The enzyme activity of beta-glucosidase and the mass ratio of aucubin are that poliosis can be dyed black by 8 ~ 20U:1mg.
figure of description
Fig. 1: hair dye is to the effect of hair.
Fig. 2: the kind of hair dye and hair dyeing mechanism.
Detailed description of the invention
Below in conjunction with embodiment, technical scheme of the present invention is described further, but protection scope of the present invention is not limited to this.
Embodiment 1
Permanent Hair Dyeing Agent prepared by the dyestuff of the natural botanical source of the present embodiment and enzyme is made up of I dose, II dose two components, specific as follows:
The preparation of I dose: with the hydroxyethyl-cellulose of the swelling 4g of 66.2g deionized water, add 3g glycerol, 1.5g dimethicone, 25g aucubin (purity 60%), 0.1g soluble perfume, 0.2g sodium hydroxy methyl glycinate, potassium hydroxide with 10% adjusts pH to 8, stirs 15 ~ 20min, discharging;
The preparation of II dose: 37.5g deionized water is heated to 70 ~ 80 DEG C, get 16.88g deionized water and add 1.8g triethyl citrate, 0.9g mono stearate glyceryl ester, 1.1g tween 80, emulsify at a high speed is sheared, the now solid content of emulsifying liquid about 15%, as foam too much can add dimethicone froth breaking in right amount, again 9.38g deionized water is added in this emulsifying liquid, be stirred to room temperature, this emulsified mixed suspension liquid is poured in 58.7g methacrylic acid and ethyl acrylate (1:1) aqueous copolymer dispersion (polymer content 30%), moderate-speed mixer, again by advance with 11.25g deionized water dissolving 2.9g beta-glucosidase (Rate activity of this enzyme is 40U/mg), enzymatic solution prepared by 0.01g sodium sulfite is poured methacrylic acid and ethyl acrylate (1:1) copolymer solution into and is stirred 20 ~ 50min(300 ~ 1000r/min, 30 ~ 45 DEG C), the now solid content of emulsifying liquid about 25%.This emulsion spray drying namely obtained II dose, spray-dired condition is: inlet temperature 80 ~ 180 DEG C, leaving air temp 50 ~ 120 DEG C.
Have hair dyed according to using method, by I dose, II dose Homogeneous phase mixing, 40 ~ 50 DEG C of insulation about 20 ~ 30min are for subsequent use, use hairdressing to commonly use softening agent the hair scale sheet of hair epidermal area is opened simultaneously, wash softening agent with water after 10 ~ 15min, then the mixture of I dose, II dose is spread upon on hair, 40 ~ 50 DEG C of insulation 30 ~ 60min, namely washing totally completes dyeing, dyes brown.
Embodiment 2
Permanent Hair Dyeing Agent prepared by the dyestuff of the natural botanical source of the present embodiment and enzyme is made up of I dose, II dose two components, specific as follows:
The preparation of I dose: with the hydroxyethyl-cellulose of the swelling 4g of 64.9g deionized water, add 3g glycerol, 1.8g dimethicone, 26g aucubin (purity 60%), 0.1g soluble perfume, 0.2g sodium hydroxy methyl glycinate, potassium hydroxide with 10% adjusts pH to 8.5, stirs 15 ~ 20min, discharging;
The preparation of II dose: 37.5g deionized water is heated to 70 ~ 80 DEG C, get 16.88g deionized water and add 1.8g triethyl citrate, 0.9g mono stearate glyceryl ester, 1.1g tween 80, emulsify at a high speed is sheared, the now solid content of emulsifying liquid about 15%, as foam too much can add dimethicone froth breaking in right amount, again 9.38g deionized water is added in this emulsifying liquid, be stirred to room temperature, this emulsified mixed suspension liquid is poured in 58.7g methacrylic acid and ethyl acrylate (1:1) aqueous copolymer dispersion (polymer content 30%), moderate-speed mixer, again by advance with 11.25g deionized water dissolving 3.8g beta-glucosidase (Rate activity of this enzyme is 30U/mg), enzymatic solution prepared by 0.01g sodium sulfite is poured methacrylic acid and ethyl acrylate (1:1) copolymer solution into and is stirred 20 ~ 50min(300 ~ 1000r/min, 30 ~ 45 DEG C), the now solid content of emulsifying liquid about 25%.This emulsion spray drying namely obtained II dose, spray-dired condition is: inlet temperature 80 ~ 180 DEG C, leaving air temp 50 ~ 120 DEG C.
Have hair dyed according to using method, by I dose, II dose Homogeneous phase mixing, 40 ~ 50 DEG C of insulation about 20 ~ 30min are for subsequent use, use hairdressing to commonly use softening agent the hair scale sheet of hair epidermal area is opened simultaneously, wash softening agent with water after 10 ~ 15min, then the mixture of I dose, II dose is spread upon on hair, 40 ~ 50 DEG C of insulation 30 ~ 60min, namely washing totally completes dyeing, and hair is dyed brown.
Embodiment 3
Permanent Hair Dyeing Agent prepared by the dyestuff of the natural botanical source of the present embodiment and enzyme is made up of I dose, II dose two components, specific as follows:
The preparation of I dose: with the hydroxyethyl-cellulose of the swelling 4g of 65.6g deionized water, add 2.5g glycerol, 1.5g dimethicone, 26g aucubin (purity 60%), 0.2g soluble perfume, 0.2g sodium hydroxy methyl glycinate, potassium hydroxide with 10% adjusts pH to 7, stirs 15 ~ 20min, discharging;
The preparation of II dose: 37.5g deionized water is heated to 70 ~ 80 DEG C, get 16.88g deionized water and add 1.8g triethyl citrate, 0.9g mono stearate glyceryl ester, 1.1g tween 80, emulsify at a high speed is sheared, the now solid content of emulsifying liquid about 15%, as foam too much can add dimethicone froth breaking in right amount, again 9.38g deionized water is added in this emulsifying liquid, be stirred to room temperature, this emulsified mixed suspension liquid is poured in 58.7g methacrylic acid and ethyl acrylate (1:1) aqueous copolymer dispersion (polymer content 30%), moderate-speed mixer, again by advance with 11.25g deionized water dissolving 6.5g beta-glucosidase (Rate activity of this enzyme is 30U/mg), enzymatic solution prepared by 0.01g sodium sulfite is poured methacrylic acid and ethyl acrylate (1:1) copolymer solution into and is stirred 20 ~ 50min(300 ~ 1000r/min, 30 ~ 45 DEG C), the now solid content of emulsifying liquid about 25%.This emulsion spray drying namely obtained II dose, spray-dired condition is: inlet temperature 80 ~ 180 DEG C, leaving air temp 50 ~ 120 DEG C.
Have hair dyed according to using method, by I dose, II dose Homogeneous phase mixing, 40 ~ 50 DEG C of insulation about 20 ~ 30min are for subsequent use, use hairdressing to commonly use softening agent the hair scale sheet of hair epidermal area is opened simultaneously, wash softening agent with water after 10 ~ 15min, then the mixture of I dose, II dose is spread upon on hair, 40 ~ 50 DEG C of insulation 30 ~ 60min, namely washing totally completes dyeing, and hair dyes black.
Embodiment 4
Permanent Hair Dyeing Agent prepared by the dyestuff of the natural botanical source of the present embodiment and enzyme is made up of I dose, II dose two components, specific as follows:
The preparation of I dose: with the hydroxyethyl-cellulose of the swelling 3.5g of 73.1g deionized water, add 2.5g glycerol, 1.5g dimethicone, 19g aucubin (purity 80%), 0.2g soluble perfume, 0.2g sodium hydroxy methyl glycinate, the potassium hydroxide with 10% adjusts pH to 9, stir 15 ~ 20min, discharging;
The preparation of II dose: 37.5g deionized water is heated to 70 ~ 80 DEG C, get 16.88g deionized water and add 1.8g triethyl citrate, 0.9g mono stearate glyceryl ester, 1.1g tween 80, emulsify at a high speed is sheared, the now solid content of emulsifying liquid about 15%, as foam too much can add dimethicone froth breaking in right amount, again 9.38g deionized water is added in this emulsifying liquid, be stirred to room temperature, this emulsified mixed suspension liquid is poured in 58.7g methacrylic acid and ethyl acrylate (1:1) aqueous copolymer dispersion (polymer content 30%), moderate-speed mixer, again by advance with 11.25g deionized water dissolving 4.7g beta-glucosidase (Rate activity of this enzyme is 40U/mg), enzymatic solution prepared by 0.01g sodium sulfite is poured methacrylic acid and ethyl acrylate (1:1) copolymer solution into and is stirred 20 ~ 50min(300 ~ 1000r/min, 30 ~ 45 DEG C), the now solid content of emulsifying liquid about 25%.This emulsion spray drying namely obtained II dose, spray-dired condition is: inlet temperature 80 ~ 180 DEG C, leaving air temp 50 ~ 120 DEG C.
Have hair dyed according to using method, by I dose, II dose Homogeneous phase mixing, 40 ~ 50 DEG C of insulation about 20 ~ 30min are for subsequent use, use hairdressing to commonly use softening agent the hair scale sheet of hair epidermal area is opened simultaneously, wash softening agent with water after 10 ~ 15min, then the mixture of I dose, II dose is spread upon on hair, 40 ~ 50 DEG C of insulation 30 ~ 60min, namely washing totally completes dyeing, and hair dyes black.
Embodiment 5
Permanent Hair Dyeing Agent prepared by the dyestuff of the natural botanical source of the present embodiment and enzyme is made up of I dose, II dose two components, specific as follows:
The preparation of I dose: with the hydroxyethyl-cellulose of the swelling 3.5g of 72.8g deionized water, add 2.5g glycerol, 1.8g dimethicone, 19g aucubin (purity 80%), 0.2g soluble perfume, 0.2g sodium hydroxy methyl glycinate, the potassium hydroxide with 10% adjusts pH to 7.5, stir 15 ~ 20min, discharging;
The preparation of II dose: 37.5g deionized water is heated to 70 ~ 80 DEG C, get 16.88g deionized water and add 1.8g triethyl citrate, 0.9g mono stearate glyceryl ester, 1.1g tween 80, emulsify at a high speed is sheared, the now solid content of emulsifying liquid about 15%, as foam too much can add dimethicone froth breaking in right amount, again 9.38g deionized water is added in this emulsifying liquid, be stirred to room temperature, this emulsified mixed suspension liquid is poured in 58.7g methacrylic acid and ethyl acrylate (1:1) aqueous copolymer dispersion (polymer content 30%), moderate-speed mixer, again by advance with 11.25g deionized water dissolving 3.9g beta-glucosidase (Rate activity of this enzyme is 30U/mg), enzymatic solution prepared by 0.01g sodium sulfite is poured methacrylic acid and ethyl acrylate (1:1) copolymer solution into and is stirred 20 ~ 50min(300 ~ 1000r/min, 30 ~ 45 DEG C), the now solid content of emulsifying liquid about 25%.This emulsion spray drying namely obtained II dose, spray-dired condition is: inlet temperature 80 ~ 180 DEG C, leaving air temp 50 ~ 120 DEG C.
Have hair dyed according to using method, by I dose, II dose Homogeneous phase mixing, 40 ~ 50 DEG C of insulation about 20 ~ 30min are for subsequent use, use hairdressing to commonly use softening agent the hair scale sheet of hair epidermal area is opened simultaneously, wash softening agent with water after 10 ~ 15min, then the mixture of I dose, II dose is spread upon on hair, 40 ~ 50 DEG C of insulation 30 ~ 60min, namely washing totally completes dyeing, and hair is dyed brown.
Embodiment 6
Permanent Hair Dyeing Agent prepared by the dyestuff of the natural botanical source of the present embodiment and enzyme is made up of I dose, II dose two components, specific as follows:
The preparation of I dose: with the hydroxyethyl-cellulose of the swelling 3.5g of 71.4g deionized water, add 3g glycerol, 1.8g dimethicone, 20g aucubin (purity 80%), 0.1g soluble perfume, 0.2g sodium hydroxy methyl glycinate, the potassium hydroxide with 10% adjusts pH to 6.5, stir 15 ~ 20min, discharging;
The preparation of II dose: 37.5g deionized water is heated to 70 ~ 80 DEG C, get 16.88g deionized water and add 1.8g triethyl citrate, 0.9g mono stearate glyceryl ester, 1.1g tween 80, emulsify at a high speed is sheared, the now solid content of emulsifying liquid about 15%, as foam too much can add dimethicone froth breaking in right amount, again 9.38g deionized water is added in this emulsifying liquid, be stirred to room temperature, this emulsified mixed suspension liquid is poured in 58.7g methacrylic acid and ethyl acrylate (1:1) aqueous copolymer dispersion (polymer content 30%), moderate-speed mixer, again by advance with 11.25g deionized water dissolving 4.8g beta-glucosidase (Rate activity of this enzyme is 40U/mg), enzymatic solution prepared by 0.01g sodium sulfite is poured methacrylic acid and ethyl acrylate (1:1) copolymer solution into and is stirred 20 ~ 50min(300 ~ 1000r/min, 30 ~ 45 DEG C), the now solid content of emulsifying liquid about 25%.This emulsion spray drying namely obtained II dose, spray-dired condition is: inlet temperature 80 ~ 180 DEG C, leaving air temp 50 ~ 120 DEG C.
Have hair dyed according to using method, by I dose, II dose Homogeneous phase mixing, 40 ~ 50 DEG C of insulation about 20 ~ 30min are for subsequent use, use hairdressing to commonly use softening agent the hair scale sheet of hair epidermal area is opened simultaneously, wash softening agent with water after 10 ~ 15min, then the mixture of I dose, II dose is spread upon on hair, 40 ~ 50 DEG C of insulation 30 ~ 60min, namely washing totally completes dyeing, and hair dyes black.
Claims (8)
1. a kind of Permanent Hair Dyeing Agent prepared by dyestuff and the enzyme of natural botanical source of the present invention, is characterized in that it is made up of following I dose (unguentum, pH6 ~ 10), II dose (powder) two components:
(1) I dose comprises following component by weight percentage: aucubin 16 ~ 30%, hydroxyethyl-cellulose 3 ~ 6%, glycerol 2 ~ 4%, dimethicone 1 ~ 2%, soluble perfume 0.1 ~ 0.4%, antiseptic 0 ~ 0.3%, balance deionized water is supplied, and the potassium hydroxide with 10% adjusts pH to 6 ~ 10;
(2) II doses by beta-glucosidase 1 ~ 10%, sodium sulfite 0 ~ 0.1%, methacrylic acid and ethyl acrylate (1:1) aqueous copolymer dispersion (polymer content 30%) 50 ~ 60%, triethyl citrate 1 ~ 2%, mono stearate glyceryl ester 0.5 ~ 1%, tween 80 0.5 ~ 1.5%, balance deionized water is supplied, and the suspension made is spray-dried obtained.
2. the invention provides the manufacture method of above-mentioned hair dye:
The preparation method of (1) I dose is: with the hydroxyethyl-cellulose of deionized water swelling 3 ~ 6%, add 2 ~ 4% glycerol, 1 ~ 2% dimethicone, aucubin 16 ~ 30%, 0.1 ~ 0.4% soluble perfume, 0 ~ 0.3% antiseptic, balance deionized water is supplied, potassium hydroxide with 10% adjusts pH to 6 ~ 8, stirs 15 ~ 20min, discharging;
(2) II doses of preparation methoies are: the deionized water accounting for total amount of deionized water 45% is heated to 70 ~ 80 DEG C, add triethyl citrate 1 ~ 2%, mono stearate glyceryl ester 0.5 ~ 1%, tween 80 0.5 ~ 1.5%, emulsify at a high speed is sheared, the now solid content of emulsifying liquid about 15%, as foam too much can add dimethicone froth breaking in right amount, again the deionized water accounting for total Water 25% is added in this emulsifying liquid, be stirred to room temperature, this emulsified mixed suspension liquid is poured into methacrylic acid and ethyl acrylate (1:1) aqueous copolymer dispersion (polymer content 30%) of 50 ~ 60%, moderate-speed mixer, again by advance with the beta-glucosidase 1 ~ 10% of deionized water dissolving accounting for total Water 30%, enzyme liquid prepared by sodium sulfite 0 ~ 0.1% is poured methacrylic acid and ethyl acrylate (1:1) copolymer solution into and is stirred 20 ~ 50min(300 ~ 1000r/min, 30 ~ 45 DEG C), the now solid content of emulsifying liquid about 25%, this emulsion spray drying namely obtained II dose, spray-dired condition is: inlet temperature 80 ~ 180 DEG C, leaving air temp 50 ~ 120 DEG C.
3. aucubin according to claim 1 and 2, beta-glucosidase are from plant material, adopt conventional extracting method to prepare, and preferential water or the alcohol of using extracts; In actual production, the commercial prod that aucubin, beta-glucosidase can extract from suppliers buying from plant material; For saving cost, the preferred purity 60 ~ 80% of aucubin, the optional thick enzyme of beta-glucosidase, specific activity of enzyme is 20 ~ 50U/mg preferably, more preferably 30 ~ 40U/mg.
4. in hair dye according to claim 1 and 2, the mass ratio of beta-glucosidase and aucubin is 1:1 ~ 1:10.
5. in hair dye according to claim 1 and 2 the enzyme activity of beta-glucosidase and the mass ratio of aucubin to be that poliosis can be dyed by 2 ~ 10U:1mg brown; The mass ratio of the enzyme activity of beta-glucosidase and aucubin is needed to be that poliosis can be dyed black by 8 ~ 20U:1mg.
6. antiseptic according to claim 1 is alkaline antiseptic Methylisothiazolinone or sodium hydroxy methyl glycinate, and use amount is respectively 0 ~ 0.01% or 0.2 ~ 0.4%.
7. methacrylic acid according to claim 1 and 2 and ethyl acrylate (1:1) aqueous copolymer dispersion (polymer content 30%) can directly commodities purchased product as especially strange L30D-55; Or buy methacrylic acid and ethyl acrylate (1:1) copolymer, then be mixed with methacrylic acid and ethyl acrylate (1:1) aqueous copolymer dispersion (polymer content 30%) by 30% polymer content, 10%1mol/L sodium hydroxide solution, 60% deionized water.
8. the invention provides the using method of above-mentioned hair dye according to claim 1 or 2: by I dose, II dose Homogeneous phase mixing, 40 ~ 50 DEG C of insulation about 20 ~ 30min are for subsequent use, use hairdressing to commonly use softening agent the hair scale sheet of hair epidermal area is opened simultaneously, softening agent is washed with water after 10 ~ 15min, then the mixture of I dose, II dose is spread upon on hair, 40 ~ 50 DEG C of insulation 30 ~ 60min, namely washing totally completes dyeing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510182835.8A CN105456053B (en) | 2015-04-17 | 2015-04-17 | Permanent hairdye prepared by a kind of dyestuff and enzyme by natural botanical source |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510182835.8A CN105456053B (en) | 2015-04-17 | 2015-04-17 | Permanent hairdye prepared by a kind of dyestuff and enzyme by natural botanical source |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105456053A true CN105456053A (en) | 2016-04-06 |
| CN105456053B CN105456053B (en) | 2018-07-27 |
Family
ID=55594525
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510182835.8A Active CN105456053B (en) | 2015-04-17 | 2015-04-17 | Permanent hairdye prepared by a kind of dyestuff and enzyme by natural botanical source |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105456053B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109575640A (en) * | 2018-12-20 | 2019-04-05 | 罗莱生活科技股份有限公司 | A kind of grape pip dye microcapsule and its preparation method and application |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03220115A (en) * | 1990-01-23 | 1991-09-27 | Rokuro Kiyohara | Hair dyeing cosmetic |
| CN101836945A (en) * | 2010-04-13 | 2010-09-22 | 武汉大学 | Chinese medicinal hair dye and preparation method thereof |
| CN103565686A (en) * | 2012-08-06 | 2014-02-12 | 武汉科亿华科技有限公司 | Permanent plant hair dye and preparation method thereof |
| CN104480096A (en) * | 2014-11-27 | 2015-04-01 | 陕西师范大学 | Method for cross-linking polymerization of beta-glucosaccharase |
-
2015
- 2015-04-17 CN CN201510182835.8A patent/CN105456053B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03220115A (en) * | 1990-01-23 | 1991-09-27 | Rokuro Kiyohara | Hair dyeing cosmetic |
| CN101836945A (en) * | 2010-04-13 | 2010-09-22 | 武汉大学 | Chinese medicinal hair dye and preparation method thereof |
| CN103565686A (en) * | 2012-08-06 | 2014-02-12 | 武汉科亿华科技有限公司 | Permanent plant hair dye and preparation method thereof |
| CN104480096A (en) * | 2014-11-27 | 2015-04-01 | 陕西师范大学 | Method for cross-linking polymerization of beta-glucosaccharase |
Non-Patent Citations (3)
| Title |
|---|
| 姚文兵: "《生物技术制药概论》", 31 January 2010, 中国医药科技出版社 * |
| 潘卫三: "《工业药剂学》", 31 August 2006, 高等教育出版社 * |
| 蔡津生等: "《中国食药用菌工程学》", 31 January 2015, 上海科学技术文献出版社 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109575640A (en) * | 2018-12-20 | 2019-04-05 | 罗莱生活科技股份有限公司 | A kind of grape pip dye microcapsule and its preparation method and application |
| CN109575640B (en) * | 2018-12-20 | 2020-07-14 | 罗莱生活科技股份有限公司 | Grape seed dye microcapsule and preparation method and application thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN105456053B (en) | 2018-07-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101812246B (en) | Mordant and hair dyeing product containing same | |
| CN101951804B (en) | Agents, compositions and devices for temporary coloring local hair areas | |
| CN101953772B (en) | Whitening sunscreen cosmetic and preparation method and application thereof | |
| CN108042379A (en) | Graphene is modified hair dye | |
| CN108210436B (en) | Microcapsule eye-tightening muscle base solution and preparation method thereof | |
| US20040121019A1 (en) | Particles comprising a biopolymer which is degradable under the effect of an electromagnetic wave as emitted by a solar radiation | |
| CN106236624A (en) | A kind of hydrogel facial film with whitening effect and preparation method thereof | |
| CN108451780A (en) | A kind of washable hair dye and preparation method thereof | |
| EP2641587A1 (en) | Use of tea polyphenols and/or tea pigments as dyes and products thereof | |
| CN105496809A (en) | Cistanche phenethyl alcohol total-glycosides micro-emulsion gel and preparation method thereof | |
| JP2002138024A (en) | Hair dyeing agent, hair dyeing set and hair dyeing method using the same | |
| CN111228200A (en) | Whitening composition, whitening essence containing whitening composition and preparation method of whitening essence | |
| CN102198058A (en) | Herbal hair dye | |
| CN110037973A (en) | A kind of tax Essence living and preparation method thereof | |
| CN105796475A (en) | Moisturizing and anti-aging cosmetics containing kohlrabi extract and preparation method of cosmetics | |
| CN104435630A (en) | Traditional Chinese medicine composition with whitening and anti-aging effects and preparation method and application of extract thereof | |
| CN109431915A (en) | A kind of natural plant composition, hair dye and its preparation method and application | |
| CN101879135A (en) | Curcuma plant hair dye | |
| CN105456053A (en) | Permanent hair dye prepared from dye and enzyme sourced from natural plants | |
| CN111012684B (en) | Anti-allergic hair dye and preparation method thereof | |
| CN104288032A (en) | Method for extracting mignonettetree pigment and application of the extract | |
| CN106562894B (en) | Whitening and anti-aging, antianaphylactic orange peel glycoside composition and purposes and preparation | |
| CN107233233A (en) | A kind of cosmetic composition containing rose hip oil and preparation method thereof | |
| CN101222910A (en) | Composition for hairdye comprising mulberry, mulberry leaves or mori radicis cortex | |
| JP2001064131A (en) | Hair dye and hair-dyeing method using the same |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CP03 | Change of name, title or address | ||
| CP03 | Change of name, title or address |
Address after: 437300, No. 439 Hebei Avenue, Chimagang, Chibi City, Xianning City, Hubei Province Patentee after: Wuhan Kailai Technology Co.,Ltd. Address before: Room 08, 19th Floor, Building 9, Guannan Fuxing Pharmaceutical Park, No. 58 Guanggu Avenue, Donghu New Technology Development Zone, Wuhan City, Hubei Province, 430074 Patentee before: WUHAN HAIJIYA BIOTECHNOLOGY Co.,Ltd. |