CN105431046B - 用于靶细胞中的动作电位的光遗传学调节的装置、系统和方法 - Google Patents

用于靶细胞中的动作电位的光遗传学调节的装置、系统和方法 Download PDF

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CN105431046B
CN105431046B CN201480034080.0A CN201480034080A CN105431046B CN 105431046 B CN105431046 B CN 105431046B CN 201480034080 A CN201480034080 A CN 201480034080A CN 105431046 B CN105431046 B CN 105431046B
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light
protein
amino acid
cell
seq
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CN105431046A (zh
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K·A·戴塞鲁斯
E·A·费伦齐
P·黑格曼
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University Berlin Humboldt
Leland Stanford Junior University
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CN201480034080.0A 2013-04-29 2014-04-29 用于靶细胞中的动作电位的光遗传学调节的装置、系统和方法 Expired - Fee Related CN105431046B (zh)

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US201361817221P 2013-04-29 2013-04-29
US61/817,221 2013-04-29
PCT/US2014/035900 WO2014179331A2 (en) 2013-04-29 2014-04-29 Devices, systems and methods for optogenetic modulation of action potentials in target cells

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CN105431046B true CN105431046B (zh) 2020-04-17

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US (2) US10220092B2 (enExample)
EP (1) EP2991491B1 (enExample)
JP (2) JP6549559B2 (enExample)
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AU (2) AU2014260101B2 (enExample)
CA (1) CA2908864A1 (enExample)
WO (1) WO2014179331A2 (enExample)

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US11275079B2 (en) * 2017-07-03 2022-03-15 Massachusetts Institute Of Technology Genetically encoded red fluorescent voltage sensors enabling millivolt-resolution and high-speed neural voltage imaging
CN111565698A (zh) 2017-10-10 2020-08-21 麻省理工学院 用于预防、减轻和/或治疗痴呆的系统和方法
US10960225B2 (en) 2017-10-10 2021-03-30 Massachusetts Institute Of Technology Systems and methods for preventing, mitigating, and/or treating dementia via visual stimulation that binds higher order brain regions, reduces neurodegeneration and neuroinflammation, and improves cognitive function
CN112469472B (zh) * 2018-05-31 2024-01-26 琳妮·比尔斯顿 用于治疗口腔和咽部疾病的系统、装置和方法
US11858969B2 (en) 2018-09-18 2024-01-02 California Institute Of Technology Engineered light-sensitive proteins
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AU2020355109B2 (en) * 2019-09-25 2025-06-12 The Board Of Trustees Of The Leland Stanford Junior University Thalamic input to orbitofrontal cortex drives brain-wide, frequency-dependent inhibition mediated by GABA and zona incerta
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