CN105396033B - A kind of Chinese medicine preparation and preparation method thereof for treating poultry globidiosis - Google Patents
A kind of Chinese medicine preparation and preparation method thereof for treating poultry globidiosis Download PDFInfo
- Publication number
- CN105396033B CN105396033B CN201510850898.6A CN201510850898A CN105396033B CN 105396033 B CN105396033 B CN 105396033B CN 201510850898 A CN201510850898 A CN 201510850898A CN 105396033 B CN105396033 B CN 105396033B
- Authority
- CN
- China
- Prior art keywords
- chinese medicine
- parts
- globidiosis
- preparation
- poultry
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9064—Amomum, e.g. round cardamom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
- A61K36/575—Magnolia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/708—Rheum (rhubarb)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/70—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in livestock or poultry
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
A kind of Chinese medicine preparation and preparation method thereof for treating poultry globidiosis, it is made of kuh-seng, rheum officinale, Cortex Phellodendri, Cortex Magnoliae Officinalis, tsaoko, Java brucea, purslane and fortune windmillpalm sheath-fibre, preparation dosage form is oral solution, above-mentioned Chinese medicine is added water to cook, is filtered, is concentrated and filling and sealing sterilizing, gained are the traditional Chinese medicine oral liquid for treating poultry globidiosis.It is of the present invention treatment poultry globidiosis Chinese medicine preparation and preparation method thereof, Chinese medicine formula in kuh-seng, tsaoko, Java brucea have insecticidal action, Cortex Phellodendri, Cortex Magnoliae Officinalis, purslane anti-inflammation and sterilization can treat enteritis while mitigate a series of symptoms caused by enteritis；Purslane, fortune windmillpalm sheath-fibre have the function of clearing away heat to stop bleeding, the case where illness poultry hemorrhage of digestive tract can be alleviated, dosage form used in Chinese medicine preparation of the present invention is oral solution, oral solution can not only control the intake of illness poultry, and medication is convenient, palatability is good, easy absorb, is quick.
Description
Technical field
The invention mainly relates to a kind of veterinary Chinese medicine formula and preparation method thereof, specially a kind of poultry globidiosis for the treatment of
Chinese medicine preparation and preparation method thereof.
Background technique
Globidiosis is common a kind of intestines problem during feeding, be mainly in temperature is higher, the humidity biggish spring,
Summer is often to appear in the animals such as chicken, rabbit, ox, duck caused by the helminth in enteron aisle.Since this disease has relatively by force
Harmfulness and generality, the death rate is up to 20% or more, can lead to poultry, meat and egg production and heavy losses, large quantities of livestock and poultry occurs
Morbidity and death；Animal growth and development and production performance are hindered, feed economy and nutritive value are reduced, makes to raise under livestock and poultry benefit
Drop.
Globidiosis be due to enteral helminth mass propagation and growth lead to disease caused by tissue damage, this
The life cycle of kind helminth is generally at 4-8 days.Livestock and poultry eat after the soil with infectious egg capsule, feed or drinking-water, parasitic
Worm starts to breed and be survived under suitable temperature, humidity and Oxygen Condition, keeps a large amount of coccidia implantation in enteron aisle chimeric
Between enterocyte.Since Coccidian Species are different so pathogenicity is also different, infect quantity number also it is made to show difference
Symptom.Livestock and poultry not of the same race have a different coccidias, and then non-cross infection between coccidia.Due to coccidia reproduction speed pole
Fastly, red blood cell number and cell pack can be made to reduce by 50%, enterocyte disintegration rapidly results in intestinal tissue damage.Enteron aisle is digestion
With the vitals of absorption, intestinal tissue by coccidia it is parasitic after, abilities of digestive and absorption is affected, livestock and poultry feed intake sharply under
Phenomena such as drop prevents it from the nutritional ingredient in normal absorption feed, finally results in dehydration, hematochezia, death.
The main means of prevention of poultry class globidiosis is the treatment by chemicals at present, but prolonged use
Drug is learned, the drug resistance of coccidia on the one hand can be improved, on the other hand will appear the residue problem of drug in the meat egg of poultry, this
It is two hang-ups for needing to solve when being prevented using chemicals.
Have many advantages, such as using herbal control globidiosis, pure natural ingredient can in poultry body tachymetabolism,
Toxic side effect is smaller and enhances the immunity of poultry body while worm is killed in suppression, promotes the growth of poultry from side.At present
The Chinese medicinal formulae of the prevention and treatment poultry class globidiosis used on the market mostly all use powder form, can only spice administration, still
Because the appetite of poultry can decline to a great extent after globidiosis once infects, there are spice administration medicine dosage big, absorption difference and use
The disadvantages of medicine is at high cost, and because illness poultry appetite declines, it cannot be guaranteed that enough doses control the state of an illness.
Summary of the invention
The present invention be solve to prevent and treat on the market at present poultry globidiosis chemicals residue it is more and toxic side effect is big lacks
Point, the technical problems such as middle medicinal herbs powder intake is not easy to control, provide a kind of Chinese medicine preparation for treating poultry class globidiosis and
Preparation method, can while parasitosis is killed in suppression by using the traditional Chinese medicine oral liquid that a variety of Chinese herbal medicine compatibilities are composed
The flexibly intake of control illness poultry drug, enhances poultry immunity of organisms, promotes poultry growth, reduces the hair of globidiosis
It is raw.
The present invention asks to solve that chemicals residue is more, toxic side effect is big and Chinese herbal medicine powder intake is not easy to control etc.
Inscribe taken technical solution are as follows:
A kind of Chinese medicine preparation for treating poultry globidiosis, according to weight ratio, the Chinese medicine preparation by 10-20 parts of kuh-sengs,
8-15 parts of rheum officinales, 8-15 portions of Cortex Phellodendris, 8-15 parts of Cortex Magnoliae Officinalis, 8-15 parts of tsaokos, 8-15 parts of Java brucea, 12-20 portions of purslanes and 10-20
Part fortune windmillpalm sheath-fibre composition.
Preferably, Chinese medicine preparation is according to weight ratio by 14 parts of kuh-sengs, 10 parts of rheum officinales, 12 portions of Cortex Phellodendris, 12 parts of Cortex Magnoliae Officinalis, 12 parts of grass
Fruit, 10 parts of Java brucea, 16 portions of purslanes and 14 parts of fortune windmillpalm sheath-fibre compositions.
A kind of preparation method of Chinese medicine preparation that treating poultry globidiosis, the dosage form of the Chinese medicine preparation are oral solution,
Preparation method the following steps are included:
Step 1: tsaoko and Java brucea are smashed respectively, kuh-seng, rheum officinale, Cortex Phellodendri, Cortex Magnoliae Officinalis are thinly sliced respectively, purslane
With fortune windmillpalm sheath-fibre dissection, after in proportion mixing above-mentioned Chinese medicine in clean container, the water of 8 times of amounts is added to impregnate 2 hours；
Step 2: heating the container, Chinese medicine 2 hours in container are decocted, water are persistently added during decoction, until in container
When the liquid of remaining 4 times of amounts, medicine soup a and the solid dregs of a decoction are filtered to obtain, it is spare；The water of 6 times of solid dregs of a decoction amounts is added again into container
It is secondary to decoct 1.5 hours, it keeps adding water during decoction, until filtering to obtain medicine soup b when the liquid of remaining 3 times of amounts in container；By medicine
Soup a and medicine soup b mixing, obtains medicine soup c, spare；
Step 3: medicine soup c to be concentrated under reduced pressure into the half of original volume, stand at low temperature 12 hours, standby under conditions of 1-4 DEG C
With；
Step 4: to the medicine soup c centrifugal treating after gained concentration in step 3, revolving speed 4000r/min takes supernatant mistake
Filtrate a is obtained after filter, it is spare；
Step 5: pharmaceutical preservative is added in filtrate a, and is adjusted with deionized water to every milliliter and be equivalent to crude drug
1.5g；Filling and sealing sterilizing, gained are the traditional Chinese medicine oral liquid for treating poultry globidiosis.
The sterilization method is to be sterilized 45 minutes under conditions of 95 DEG C, 0.1kPa using water-bath type sterilizing cabinet.
Pharmaceutical preservative in the step 5 is sodium benzoate, and additional amount accounts for the 0.03% of filtrate a volume.
Beneficial effects of the present invention:
A kind of Chinese medicine preparation and preparation method thereof for treating poultry globidiosis of the present invention, Chinese medicine formula in hardship
Ginseng, tsaoko, Java brucea have insecticidal action, and poultry can inhibit the breeding of internal coccidia after taking, kuh-seng, rheum officinale can promote ball
Worm's ovum capsule and toxin discharge, Cortex Phellodendri, Cortex Magnoliae Officinalis, purslane anti-inflammation and sterilization can treat enteritis while mitigate a series of caused by enteritis
Symptom；The case where purslane, fortune windmillpalm sheath-fibre have the function of clearing away heat to stop bleeding, can alleviate illness poultry hemorrhage of digestive tract, the present invention
The Chinese medicine preparation can inhibit coccidia breeding, and can improve the series reaction because of caused by coccidiosis infection, as diarrhea,
Hematochezia etc., and overcoming traditional veterinary Chinese medicine dosage form is mostly powder carries out mixing food administration not can control intake to illness poultry
The disadvantages of, dosage form used in Chinese medicine preparation of the present invention is oral solution, and oral solution can not only control illness poultry
Intake, and medication is convenient, palatability is good, easy absorb, is quick.
Specific embodiment
In conjunction with following specific embodiments, the present invention is described in further detail, and protection scope of the present invention is not limited to
In following embodiment.Implement process of the invention, condition, reagent, experimental method etc., in addition to what is specifically mentioned below,
It is among the general principles and common general knowledge in the art, there are no special restrictions to content by the present invention.
Embodiment 1
Treat the preparation method of the traditional Chinese medicine oral liquid of poultry globidiosis, preparation method the following steps are included:
8 parts of tsaokos, 8 parts of Java brucea are smashed respectively, 10 parts of kuh-sengs, 8 parts of rheum officinales, 8 portions of Cortex Phellodendris, 8 parts of Cortex Magnoliae Officinalis are cut into respectively
Thin slice, 12 portions of purslanes and 10 parts of fortune windmillpalm sheath-fibre dissections after above-mentioned Chinese medicine mixes in clean container, add the water of 8 times of amounts to impregnate 2 small
When；
Step 2: heating the container, Chinese medicine 2 hours in container are decocted, water are persistently added during decoction, until in container
When the liquid of remaining 4 times of amounts, medicine soup a and the solid dregs of a decoction are filtered to obtain, it is spare；The water of 6 times of solid dregs of a decoction amounts is added again into container
It is secondary to decoct 1.5 hours, it keeps adding water during decoction, until filtering to obtain medicine soup b when the liquid of remaining 3 times of amounts in container；By medicine
Soup a and medicine soup b mixing, obtains medicine soup c, spare；
Step 3: medicine soup c to be concentrated under reduced pressure into the half of original volume, stand at low temperature 12 hours, standby under conditions of 1 DEG C
With；
Step 4: to the medicine soup c centrifugal treating after gained concentration in step 3, revolving speed 4000r/min takes supernatant mistake
Filtrate a is obtained after filter, it is spare；
Step 5: the sodium benzoate for accounting for filtrate a volume 0.03% is added in filtrate a, and adjusted with deionized water to every milli
It rises and is equivalent to crude drug 1.5g；Filling and sealing simultaneously sterilized using water-bath type sterilizing cabinet, and sterilising conditions are 95 DEG C, 0.1kPa
In the case of sterilization treatment 45min, gained be treat poultry globidiosis traditional Chinese medicine oral liquid.
Embodiment 2
Treat the preparation method of the traditional Chinese medicine oral liquid of poultry globidiosis, preparation method the following steps are included:
10 parts of tsaokos, 9 parts of Java brucea are smashed respectively, 12 parts of kuh-sengs, 9 parts of rheum officinales, 10 portions of Cortex Phellodendris, 10 parts of Cortex Magnoliae Officinalis are cut respectively
Flakiness, 14 portions of purslanes and 12 parts of fortune windmillpalm sheath-fibre dissections after above-mentioned Chinese medicine mixes in clean container, add the water of 8 times of amounts to impregnate 2
Hour；
Step 2: heating the container, Chinese medicine 2 hours in container are decocted, water are persistently added during decoction, until in container
When the liquid of remaining 4 times of amounts, medicine soup a and the solid dregs of a decoction are filtered to obtain, it is spare；The water of 6 times of solid dregs of a decoction amounts is added again into container
It is secondary to decoct 1.5 hours, it keeps adding water during decoction, until filtering to obtain medicine soup b when the liquid of remaining 3 times of amounts in container；By medicine
Soup a and medicine soup b mixing, obtains medicine soup c, spare；
Step 3: medicine soup c to be concentrated under reduced pressure into the half of original volume, stand at low temperature 12 hours, standby under conditions of 2 DEG C
With；
Step 4: to the medicine soup c centrifugal treating after gained concentration in step 3, revolving speed 4000r/min takes supernatant mistake
Filtrate a is obtained after filter, it is spare；
Step 5: the sodium benzoate for accounting for filtrate a volume 0.03% is added in filtrate a, and adjusted with deionized water to every milli
It rises and is equivalent to crude drug 1.5g；Filling and sealing simultaneously sterilized using water-bath type sterilizing cabinet, and sterilising conditions are 95 DEG C, 0.1kPa
In the case of sterilization treatment 45min, gained be treat poultry globidiosis traditional Chinese medicine oral liquid.
Embodiment 3
Treat the preparation method of the traditional Chinese medicine oral liquid of poultry globidiosis, preparation method the following steps are included:
12 parts of tsaokos, 10 parts of Java brucea are smashed respectively, 14 parts of kuh-sengs, 10 parts of rheum officinales, 12 portions of Cortex Phellodendris, 12 parts of Cortex Magnoliae Officinalis difference
It thinly slices, 16 portions of purslanes and 14 parts of fortune windmillpalm sheath-fibre dissections, after above-mentioned Chinese medicine mixes in clean container, adds the water logging of 8 times of amounts
Bubble 2 hours；
Step 2: heating the container, Chinese medicine 2 hours in container are decocted, water are persistently added during decoction, until in container
When the liquid of remaining 4 times of amounts, medicine soup a and the solid dregs of a decoction are filtered to obtain, it is spare；The water of 6 times of solid dregs of a decoction amounts is added again into container
It is secondary to decoct 1.5 hours, it keeps adding water during decoction, until filtering to obtain medicine soup b when the liquid of remaining 3 times of amounts in container；By medicine
Soup a and medicine soup b mixing, obtains medicine soup c, spare；
Step 3: medicine soup c to be concentrated under reduced pressure into the half of original volume, stand at low temperature 12 hours, standby under conditions of 1-4 DEG C
With；
Step 4: to the medicine soup c centrifugal treating after gained concentration in step 3, revolving speed 4000r/min takes supernatant mistake
Filtrate a is obtained after filter, it is spare；
Step 5: the sodium benzoate for accounting for filtrate a volume 0.03% is added in filtrate a, and adjusted with deionized water to every milli
It rises and is equivalent to crude drug 1.5g；Filling and sealing simultaneously sterilized using water-bath type sterilizing cabinet, and sterilising conditions are 95 DEG C, 0.1kPa
In the case of sterilization treatment 45min, gained be treat poultry globidiosis traditional Chinese medicine oral liquid.
Embodiment 4
Treat the preparation method of the traditional Chinese medicine oral liquid of poultry globidiosis, preparation method the following steps are included:
14 parts of tsaokos, 13 parts of Java brucea are smashed respectively, 16 parts of kuh-sengs, 14 parts of rheum officinales, 14 portions of Cortex Phellodendris, 14 parts of Cortex Magnoliae Officinalis difference
It thinly slices, 17 portions of purslanes and 17 parts of fortune windmillpalm sheath-fibre dissections, after above-mentioned Chinese medicine mixes in clean container, adds the water logging of 8 times of amounts
Bubble 2 hours；
Step 2: heating the container, Chinese medicine 2 hours in container are decocted, water are persistently added during decoction, until in container
When the liquid of remaining 4 times of amounts, medicine soup a and the solid dregs of a decoction are filtered to obtain, it is spare；The water of 6 times of solid dregs of a decoction amounts is added again into container
It is secondary to decoct 1.5 hours, it keeps adding water during decoction, until filtering to obtain medicine soup b when the liquid of remaining 3 times of amounts in container；By medicine
Soup a and medicine soup b mixing, obtains medicine soup c, spare；
Step 3: medicine soup c to be concentrated under reduced pressure into the half of original volume, stand at low temperature 12 hours, standby under conditions of 2 DEG C
With；
Step 4: to the medicine soup c centrifugal treating after gained concentration in step 3, revolving speed 4000r/min takes supernatant mistake
Filtrate a is obtained after filter, it is spare；
Step 5: the sodium benzoate for accounting for filtrate a volume 0.03% is added in filtrate a, and adjusted with deionized water to every milli
It rises and is equivalent to crude drug 1.5g；Filling and sealing simultaneously sterilized using water-bath type sterilizing cabinet, and sterilising conditions are 95 DEG C, 0.1kPa
In the case of sterilization treatment 45min, gained be treat poultry globidiosis traditional Chinese medicine oral liquid.
Embodiment 5
Treat the preparation method of the traditional Chinese medicine oral liquid of poultry globidiosis, preparation method the following steps are included:
15 parts of tsaokos, 15 parts of Java brucea are smashed respectively, 20 parts of kuh-sengs, 15 parts of rheum officinales, 15 portions of Cortex Phellodendris, 15 parts of Cortex Magnoliae Officinalis difference
It thinly slices, 20 portions of purslanes and 20 parts of fortune windmillpalm sheath-fibre dissections, after above-mentioned Chinese medicine mixes in clean container, adds the water logging of 8 times of amounts
Bubble 2 hours；
Step 2: heating the container, Chinese medicine 2 hours in container are decocted, water are persistently added during decoction, until in container
When the liquid of remaining 4 times of amounts, medicine soup a and the solid dregs of a decoction are filtered to obtain, it is spare；The water of 6 times of solid dregs of a decoction amounts is added again into container
It is secondary to decoct 1.5 hours, it keeps adding water during decoction, until filtering to obtain medicine soup b when the liquid of remaining 3 times of amounts in container；By medicine
Soup a and medicine soup b mixing, obtains medicine soup c, spare；
Step 3: medicine soup c to be concentrated under reduced pressure into the half of original volume, stand at low temperature 12 hours, standby under conditions of 4 DEG C
With；
Step 4: to the medicine soup c centrifugal treating after gained concentration in step 3, revolving speed 4000r/min takes supernatant mistake
Filtrate a is obtained after filter, it is spare；
Step 5: the sodium benzoate for accounting for filtrate a volume 0.03% is added in filtrate a, and adjusted with deionized water to every milli
It rises and is equivalent to crude drug 1.5g；Filling and sealing simultaneously sterilized using water-bath type sterilizing cabinet, and sterilising conditions are 95 DEG C, 0.1kPa
In the case of sterilization treatment 45min, gained be treat poultry globidiosis traditional Chinese medicine oral liquid.
Application case
1, Pingdingshan chicken house, 27 Day-old Broiler Chickens 3000, occur draw tomato sample just with rotten meat sample just, choose
Food, the mixed and disorderly symptoms such as unglazed of feather, doubtful is small intestinal coccidiosis, takes stool examination, and discovery has coccidian oocyst, is diagnosed as coccidia
Disease.Drug therapy is carried out using the oral solution for the treatment of poultry globidiosis of the present invention, it is daily according to the every kg weight of every chicken
Oral this product 0.2mL, is used in conjunction 5 days；Illness chicken group is normal using excrement after the present invention 3 days, and after 5 days, hair color is bright；Continue to observe
No relapse in 10 days is considered as recovery from illness.
2, Shangqiu chicken house, 100 age in days commodity eggs 5000, it is thin excrement occur, accidental scarlet bloody stool, and feed intake is omited
Low, the symptoms such as cockscomb is yellowish-white, stool examination finds coccidian oocyst, is diagnosed as globidiosis.Use treatment poultry of the present invention
The oral solution of globidiosis carries out drug therapy, takes orally this product 0.4mL daily according to the every kg weight of every chicken, is used in conjunction 5 days, illness chicken
Group's excrement is normal, and feeding increases, and continues to be observed continuously 10 days, no relapse is considered as recovery from illness.
Claims (6)
1. a kind of Chinese medicine composition for treating poultry globidiosis, it is characterised in that: according to weight ratio, the Chinese medicine composition by
10-20 parts of kuh-sengs, 8-15 parts of rheum officinales, 8-15 portions of Cortex Phellodendris, 8-15 parts of Cortex Magnoliae Officinalis, 8-15 parts of tsaokos, 8-15 parts of Java brucea, 12-20 parts
Purslane and 10-20 parts of fortune windmillpalm sheath-fibre compositions.
2. a kind of Chinese medicine composition for treating poultry globidiosis as described in claim 1, it is characterised in that: according to weight ratio,
The Chinese medicine composition is by 14 parts of kuh-sengs, 10 parts of rheum officinales, 12 portions of Cortex Phellodendris, 12 parts of Cortex Magnoliae Officinalis, 12 parts of tsaokos, 10 parts of Java brucea, 16
Part purslane and 14 parts of fortune windmillpalm sheath-fibres compositions.
3. a kind of preparation method for the Chinese medicine composition for treating poultry globidiosis as claimed in claim 1 or 2, feature exist
In: the dosage form of the Chinese medicine composition be oral solution, preparation method the following steps are included:
Step 1: tsaoko and Java brucea are smashed respectively, kuh-seng, rheum officinale, Cortex Phellodendri, Cortex Magnoliae Officinalis are thinly sliced respectively, purslane and palm fibre
Palmitic acid skin dissection after in proportion mixing above-mentioned Chinese medicine in clean container, adds the water of 8 times of amounts to impregnate 2 hours；
Step 2: heating the container, Chinese medicine 2 hours in container are decocted, water is persistently added during decoction, until remaining in container
When the liquid of 4 times of amounts, medicine soup a and the solid dregs of a decoction are filtered to obtain, it is spare；The water that 6 times of solid dregs of a decoction amounts are added into container is decocted again
It boils 1.5 hours, keeps adding water during decoction, until filtering to obtain medicine soup b when the liquid of remaining 3 times of amounts in container；By medicine soup a
It is mixed with medicine soup b, obtains medicine soup c, it is spare；
Step 3: medicine soup c is concentrated under reduced pressure into the half of original volume, it is stand at low temperature 12 hours, spare；
Step 4: to the medicine soup c centrifugal treating after gained concentration in step 3, revolving speed 4000r/min, after taking supernatant liquid filtering
Filtrate a is obtained, it is spare；
Step 5: pharmaceutical preservative is added in filtrate a, and is adjusted with deionized water to every milliliter and be equivalent to crude drug 1.5g；
Filling and sealing sterilizing, gained are the traditional Chinese medicine oral liquid for treating poultry globidiosis.
4. a kind of preparation method for the Chinese medicine composition for treating poultry globidiosis as claimed in claim 3, it is characterised in that: institute
Stating the low temperature environment in step 3 is 1-4 DEG C.
5. a kind of preparation method for the Chinese medicine composition for treating poultry globidiosis as claimed in claim 3, it is characterised in that: institute
The pharmaceutical preservative stated in step 5 is sodium benzoate, and additional amount accounts for the 0.03% of filtrate a volume.
6. a kind of preparation method for the Chinese medicine composition for treating poultry globidiosis as claimed in claim 3, it is characterised in that: institute
Stating the sterilization method in step 5 is to be sterilized 45 minutes under conditions of 95 DEG C, 0.1kPa using water-bath type sterilizing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510850898.6A CN105396033B (en) | 2015-11-30 | 2015-11-30 | A kind of Chinese medicine preparation and preparation method thereof for treating poultry globidiosis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510850898.6A CN105396033B (en) | 2015-11-30 | 2015-11-30 | A kind of Chinese medicine preparation and preparation method thereof for treating poultry globidiosis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105396033A CN105396033A (en) | 2016-03-16 |
| CN105396033B true CN105396033B (en) | 2019-03-05 |
Family
ID=55462009
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510850898.6A Active CN105396033B (en) | 2015-11-30 | 2015-11-30 | A kind of Chinese medicine preparation and preparation method thereof for treating poultry globidiosis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105396033B (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102641457A (en) * | 2012-04-27 | 2012-08-22 | 山东恩康药业有限公司 | Veterinary medicine compound preparation for treating coccidiosis, preparation method of veterinary medicine compound preparation and application |
| CN103417653A (en) * | 2013-07-09 | 2013-12-04 | 山东恩康药业有限公司 | Veterinary-use compound pure Chinese herbal medicine for treating coccidium and preparation method of oral liquid of same |
| CN104208238A (en) * | 2013-09-29 | 2014-12-17 | 郑州后羿制药有限公司 | Traditional Chinese medicine composition for treating chicken coccidiosis and preparation method thereof |
-
2015
- 2015-11-30 CN CN201510850898.6A patent/CN105396033B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102641457A (en) * | 2012-04-27 | 2012-08-22 | 山东恩康药业有限公司 | Veterinary medicine compound preparation for treating coccidiosis, preparation method of veterinary medicine compound preparation and application |
| CN103417653A (en) * | 2013-07-09 | 2013-12-04 | 山东恩康药业有限公司 | Veterinary-use compound pure Chinese herbal medicine for treating coccidium and preparation method of oral liquid of same |
| CN104208238A (en) * | 2013-09-29 | 2014-12-17 | 郑州后羿制药有限公司 | Traditional Chinese medicine composition for treating chicken coccidiosis and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN105396033A (en) | 2016-03-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103006792B (en) | A kind of herbal medicine for preventing and treating livestock and poultry intestinal canal diseases and preparation method thereof and feed | |
| De Vico et al. | Urtica dioica (Stinging Nettle): A neglected plant with emerging growth promoter/immunostimulant properties for farmed fish | |
| CN103168919B (en) | Feed additive for enhancing immunity and promoting growth and feed | |
| CN102028795B (en) | Chinese pulsatilla root granules for preventing and treating livestock and poultry bacterial diseases and preparation method and premix thereof | |
| KR102213743B1 (en) | A process and the composition for increasing immunity-boosting and the growth of animals comprising herbs | |
| CN103349747A (en) | Traditional Chinese medicine preparation for preventing and curing paralichthys olivaceus and sea cucumber scuticoci liatlda diseases | |
| CN1927281A (en) | Chinese herbal medicine slow release agent for preventing and treating rabbit and chicken coccidiosis and preparing method thereof | |
| CN102640876A (en) | Feed and injection used for treating duck virus hepatitis and preparation method of feed and injection | |
| CN103860715A (en) | Compound traditional Chinese medicine extract for preventing poultry coccidiosis and application of extract | |
| CN101342273B (en) | Medicament for preventing and controlling botryomycosis of chicken | |
| CN102872307A (en) | Traditional Chinese medicine oral liquid for preventing and treating virus diseases of poultry and method for preparing traditional Chinese medicine oral liquid | |
| CN103285255B (en) | Anti-coccidiosis pharmaceutical composition as well as preparation method and use thereof | |
| CN101209296A (en) | Chinese medicinal granule with worm-expelling liver-caring, hemostasis and dysentery-stopping efficacy | |
| CN104435023A (en) | Traditional Chinese medicine extract and application thereof | |
| Al-Niaeem et al. | Using of anise (Pimpinella anisum) and chamomile (Matricaria chamomilla) powders for common carp Cyprinus carpio L. anesthesia | |
| CN101342275B (en) | Medicament for preventing and controlling aspergillus disease of chicken | |
| KR20100025958A (en) | Medical's a composite of the calf | |
| CN103070907B (en) | Medicine resistant to poultry coccidiosis and preparation method thereof | |
| CN105396033B (en) | A kind of Chinese medicine preparation and preparation method thereof for treating poultry globidiosis | |
| CN104825700A (en) | Traditional Chinese medicine composition for resisting bacteria and diminishing inflammation | |
| CN101390965A (en) | Veterinary traditional Chinese herb medicine for treating livestock and poultry bacterial and viral infectious diseases and preparation method thereof | |
| CN104840591B (en) | A kind of Chinese medicine composition for having effects that to prevent ewcastle disease | |
| Kadhim et al. | Influence of dietary supplementation of Nigella sativa on experimental coccidiosis in broiler chickens | |
| CN104606627B (en) | A kind of pharmaceutical composition for treating grice diarrhoea and preparation method thereof | |
| CN101313978B (en) | Bacillus coli vaccine oral liquid synergistic agent for livestock, poultry and aquatic product, and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |