CN105327239B - A kind of Chinese medicine composition and its preparation method and application for treating apositia of children - Google Patents
A kind of Chinese medicine composition and its preparation method and application for treating apositia of children Download PDFInfo
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- CN105327239B CN105327239B CN201410318482.5A CN201410318482A CN105327239B CN 105327239 B CN105327239 B CN 105327239B CN 201410318482 A CN201410318482 A CN 201410318482A CN 105327239 B CN105327239 B CN 105327239B
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Abstract
The present invention provides a kind of Chinese medicine composition for treating apositia of children, which mainly includes the following raw material medicine: Semen Lablab Album, Chinese yam, Poria cocos, dark plum, oyster, finger citron sliced, malt, semen ziziphi spinosae, jujube, dried longan pulp, fructus alpiniae oxyphyllae, mulberries, hawthorn, radish seed；Further, which becomes and (calculates in parts by weight): 3-15 parts of Semen Lablab Album, 1-10 parts of Chinese yam, 3-15 parts of Poria cocos, 1-8 parts of dark plum, 1-8 parts of oyster, 1-8 parts of finger citron sliced, 1-8 parts of malt, 3-15 parts of semen ziziphi spinosae, 1-8 parts of jujube, 1-8 parts of dried longan pulp, 1-8 parts of fructus alpiniae oxyphyllae, 1-8 parts of mulberries, 1-8 parts of hawthorn, 1-10 parts of radish seed.The present composition has the effect of stomach invigorating, invigorating the spleen, enhancing immunization programs for children power and vigor, brain-nourishing intelligence-benefiting.
Description
Technical field
The present invention relates to a kind of Chinese medicine compositions and its preparation method and application, and in particular to a kind of to treat apositia of children
Chinese medicine composition and its preparation method and application, belong to field of medicaments.
Background technique
Apositia refers to a kind of illness of children's longer term loss of appetite or even food refusal, relatively common in children.It is special
It is not modern society, since the unreasonable nursing of parent causes children anorexia, food refusal, nutrient imbalance disease increases increasingly, to spleen
Stomach causes to damage, and affects the decomposed transporting ability of the spleen and stomach in children.
Treatment to apositia generally uses Chinese and western drugs, but not only price is high for Western medicine, and there are also side effects for some drugs.
The Chinese prescription of the disclosed treatment baby anorexia of the prior art is also very much, but pharmaceutical preparation such as tablet, capsule, ball is made more
Agent, particle etc., by radix pseudostellariae, cortex cinnamomi, Rhizoma Atractylodis Macrocephalae, hawthorn, Divine Comedy, dry as disclosed in Chinese patent application 201210192946.3
Ginger, dried orange peel, endothelium corneum gigeriae galli, rice sprout, malt, the dried immature fruit of citron orange, Radix Glycyrrhizae form drug；Chinese patent application 201310335363.6 it is disclosed by
The drug that peach kernel, almond, cape jasmine, camphor, borneol, asafoetide, curcuma zedoary, trigone form；03111124.6 disclosure of Chinese patent application
By radix pseudostellariae, fry white peas or beans, fry Semen Coicis, stir-baked FRUCTUS CRATAEGI core, stir-baked SEMEN RAPHANI, calcined CONCHA ARCAE, fry the composition that forms of Fructus Aurantii, etc.,
It is unfavorable for children taking.
The present composition has the effect of stomach invigorating, invigorating the spleen, enhancing immunization programs for children power and vigor, brain-nourishing intelligence-benefiting.Utilize this
Inventive composition is prepared into children's drink, not only facilitates material benefit, beneficial children's health, and preservative free, safe and reliable, mouthfeel
It is good, be suitable for drinking of children, have huge development prospect.
Summary of the invention
The first purpose of this invention is to provide a kind of Chinese medicine composition for treating apositia of children.
Second object of the present invention is to provide the preparation method of the composition.
Third object of the present invention is to provide application of the composition in preparation treatment children anorexia disease drug.
The present invention solves technical problem and is achieved by the following technical solution:
A kind of Chinese medicine composition for treating apositia of children, the Chinese medicine composition mainly include the following raw material medicine: Semen Lablab Album,
Chinese yam, Poria cocos, dark plum, oyster, finger citron sliced, malt, semen ziziphi spinosae, jujube, dried longan pulp, fructus alpiniae oxyphyllae, mulberries, hawthorn, radish seed.
Further, which becomes and (calculates in parts by weight):
3-15 parts of Semen Lablab Album, 1-10 parts of Chinese yam, 3-15 parts of Poria cocos, 1-8 parts of dark plum, 1-8 parts of oyster, 1-8 parts of finger citron sliced, wheat
1-8 parts of bud, 3-15 parts of semen ziziphi spinosae, 1-8 parts of jujube, 1-8 parts of dried longan pulp, 1-8 parts of fructus alpiniae oxyphyllae, 1-8 parts of mulberries, 1-8 parts of hawthorn, Lay
1-10 parts of Fu.
Further, bulk pharmaceutical chemicals form are as follows:
3-12 parts of Semen Lablab Album, 1-7 parts of Chinese yam, 3-12 parts of Poria cocos, 1-6 parts of dark plum, 1-6 parts of oyster, 1-6 parts of finger citron sliced, wheat
1-6 parts of bud, 3-12 parts of semen ziziphi spinosae, 1-6 parts of jujube, 1-6 parts of dried longan pulp, 1-6 parts of fructus alpiniae oxyphyllae, 1-6 parts of mulberries, 1-6 parts of hawthorn, Lay
1-7 parts of Fu.
Further, bulk pharmaceutical chemicals form are as follows:
3-8 parts of Semen Lablab Album, 1-5 parts of Chinese yam, 3-8 parts of Poria cocos, 1-4 parts of dark plum, 1-4 parts of oyster, 1-4 parts of finger citron sliced, malt
1-4 parts, 3-8 parts of semen ziziphi spinosae, 1-4 parts of jujube, 1-4 parts of dried longan pulp, 1-4 parts of fructus alpiniae oxyphyllae, 1-4 parts of mulberries, 1-4 parts of hawthorn, radish
It is 1-5 parts sub-.
Further, bulk pharmaceutical chemicals form are as follows:
4 parts of Semen Lablab Album, 2 parts of Chinese yam, 4 parts of Poria cocos, 1 part of dark plum, 1 part of oyster, 1 part of finger citron sliced, 1 part of malt, semen ziziphi spinosae 4,
1 part of jujube, 2 parts of dried longan pulp, 2 parts of fructus alpiniae oxyphyllae, 2 parts of mulberries, 2 parts of hawthorn, 2 parts of radish seed.
The traditional chinese medicine composition of the invention can extract preparation according to a conventional method, and purification can also be further purified, can also be into
Customary adjuvant is added in one step, and routinely preparation process is prepared into health beverages, oral solution, granule, tablet, capsule, powder.
The general extraction methods include in water boiling and extraction, refluxing extraction, soak extraction, ultrasonic extraction or seepage pressure effects
One or more of modes；
The Extraction solvent is water or ethanol solution；It is further the ethyl alcohol of 30-80%；It is still more preferably 50-
70% ethyl alcohol；
The purifying refining methd includes water extract-alcohol precipitation, extraction or process macroporous resin column, silica gel column purification etc..
The preparation method of the traditional chinese medicine composition of the invention includes the following steps:
Step 1: oyster, semen ziziphi spinosae, fructus alpiniae oxyphyllae mixing are extracted with water；
Step 2: Semen Lablab Album, Chinese yam, Poria cocos, dark plum, finger citron sliced, malt, jujube, dried longan pulp, mulberries, hawthorn, radish seed
The extracting solution and the dregs of a decoction obtained after water extracts with step 1 mixes, and continues to be extracted with water, and obtains extracting solution, be concentrated under reduced pressure to get.
Further, extracting method described in steps 1 and 2 is to decoct extraction, refluxing extraction, soak extraction, ultrasonic extraction or diacolation
One or more of extraction mode；The extraction time is 2-10 hours, and extraction time is 1-3 times；Further, step 1,
2 extracting methods are first soak extraction, then refluxing extraction；Further, the soak extraction time is 2-10 hours, reflux
Extraction time is 1-3 times, and each extraction time is 0.5-2 hours.
A kind of health beverages for treating apositia of children, in parts by weight, drink supplementary material composition are as follows:
Raw material composition: 3-15 parts of Semen Lablab Album, 1-10 parts of Chinese yam, 3-15 parts of Poria cocos, 1-8 parts of dark plum, 1-8 parts of oyster, fingered citron
1-8 parts of piece, 1-8 parts of malt, 3-15 parts of semen ziziphi spinosae, 1-8 parts of jujube, 1-8 parts of dried longan pulp, 1-8 parts of fructus alpiniae oxyphyllae, 1-8 parts of mulberries, mountain
1-8 parts of short, bristly hair or beard, 1-10 parts of radish seed；
Auxiliary material composition: 200-300 parts of white granulated sugar, 0.1-1 parts of sodium carboxymethylcellulose, 1-10 parts of citric acid, sodium citrate
0.5-1.5 parts, 1-10 parts of essence.
Further, auxiliary material forms are as follows: and 220-290 parts of white granulated sugar, 0.15-0.7 parts of sodium carboxymethylcellulose, citric acid
1.5-7 parts, 0.6-1.2 parts of sodium citrate, 1.5-7 parts of essence；
Further, auxiliary material forms are as follows: and 240-270 parts of white granulated sugar, 0.2-0.5 parts of sodium carboxymethylcellulose, citric acid
2-5 parts, 0.5-1 parts of sodium citrate, 2-5 parts of essence；
Further, auxiliary material forms are as follows: and 260 parts of white granulated sugar, 0.29 part of sodium carboxymethylcellulose, 2.9 parts of citric acid, lemon
0.87 part of lemon acid sodium, 2.32 parts of essence.
The drink preparation method includes the following steps:
Step 1: oyster, semen ziziphi spinosae, fructus alpiniae oxyphyllae mixing are extracted with water；
Step 2: Semen Lablab Album, Chinese yam, Poria cocos, dark plum, finger citron sliced, malt, jujube, dried longan pulp, mulberries, hawthorn, radish seed
The extracting solution and the dregs of a decoction obtained after water extracts with step 1 mixes, and continues to be extracted with water, obtains extracting solution；
Step 3: the extracting solution that step 2 is obtained adds water to be settled to crude drug amount 1-5%, and filtering takes filtrate；
Step 4: be proportionally added into auxiliary material, filtering to get.
Further, extracting method described in steps 1 and 2 is to decoct extraction, refluxing extraction, soak extraction, ultrasonic extraction or diacolation
One or more of extraction mode；Further, extracting method described in steps 1 and 2 is first soak extraction, then refluxing extraction；More
Further, the soak extraction time is 2-10 hours, and refluxing extraction number is 1-3 times, and each extraction time is that 0.5-2 is small
When.
Further, adding water to be settled to crude drug amount described in step 3 is 1-4%；It further, is 1-2%；Further, raw
Dose is 1%.
Further, pasteurize is carried out to the filtrate that step 4 is obtained by filtration.
" extracting solution adds water to be settled to crude drug amount 1% " of the present invention refers to, the extraction obtained after 10g bulk pharmaceutical chemicals are extracted
Liquid adds water to be settled to 1000ml, i.e. crude drug amount is 1%.
The present composition has the effect of stomach invigorating, invigorating the spleen, enhancing immunization programs for children power and vigor, brain-nourishing intelligence-benefiting.
Specific embodiment
Different components treatment apositia of children curative effect compares prescription screening
1 experimental drug:
Prescription 1: Semen Lablab Album 4g, Chinese yam 2g, Poria cocos 4g, dark plum 1g, oyster 1g, finger citron sliced 1g, malt 1g, semen ziziphi spinosae 4, big
Jujube 1g, dried longan pulp 2g, fructus alpiniae oxyphyllae 2g, mulberries 2g, hawthorn 2g, radish seed 2g；
Prescription 2: Semen Lablab Album 4g, Chinese yam 10g, Poria cocos 3g, dark plum 1g, oyster 2g, finger citron sliced 1g, malt 3g, semen ziziphi spinosae 4g,
Jujube 1g, dried longan pulp 8g, fructus alpiniae oxyphyllae 3g, mulberries 2g, hawthorn 1g, radish seed 10g, Cordyceps militaris 3g；
Prescription 3: Semen Lablab Album 4g, Chinese yam 2g, Poria cocos 4g, dark plum 1g, oyster 1g, finger citron sliced 1g, malt 1g, semen ziziphi spinosae 4g,
Jujube 1g, dried longan pulp 2g, fructus alpiniae oxyphyllae 2g, mulberries 2g, hawthorn 2g, radish seed 2g, Cordyceps militaris 6g, wrinkled giant hyssop 5g, orange peel 3g；
Prescription 4: Semen Lablab Album 4g, Chinese yam 2g, Poria cocos 4g, dark plum 1g, oyster 1g, finger citron sliced 1g, malt 1g, semen ziziphi spinosae 4g,
Jujube 1g, dried longan pulp 2g, fructus alpiniae oxyphyllae 2g, mulberries 2g, hawthorn 2g, radish seed 2g, Cordyceps militaris 6g, kudzuvine root starch 3g, ginger 4g；
2. preparation method
In proportion by bulk pharmaceutical chemicals, oyster, semen ziziphi spinosae, fructus alpiniae oxyphyllae mixing are extracted with water；Remaining medicinal material and oyster, semen ziziphi spinosae,
Fructus alpiniae oxyphyllae mixed extract and dregs of a decoction mixing, are extracted with water, obtain extracting solution.Customary adjuvant is added and is prepared into children's drink.
3 result on trial
40 children of trier, the age, trier did not liked usually to have a meal, and appetite is not strong between 6-15 years old.
Trial method: giving children's drink prepared by prescription 1-4 to 10 drinking of children on probation respectively, noon, each at night
One bottle, 125ml/ bottles, try out a week.Trial effect is paid a return visit in the form of questionnaire, the results are shown in Table 1.
The trial effect of children's drink of 1 prescription 1-4 of table preparation
| Product efficacy | It is in good taste | Appetite improves | Adverse reaction |
| Prescription 1 is efficient | 90% | 90% | 0 |
| Prescription 2 is efficient | 80% | 60% | 0 |
| Prescription 3 is efficient | 80% | 40% | 0 |
| Prescription 4 is efficient | 70% | 40% | 0 |
The result shows that prescription 1 is improving appetite and aspect significant effect in good taste better than prescription 2,3,4.
Preparation method is investigated
Prescription: Semen Lablab Album 4g, Chinese yam 2g, Poria cocos 4g, dark plum 1g, oyster 1g, finger citron sliced 1g, malt 1g, semen ziziphi spinosae 4g, big
Jujube 1g, dried longan pulp 2g, fructus alpiniae oxyphyllae 2g, mulberries 2g, hawthorn 2g, radish seed 2g；
Preparation method 1:
Step 1: oyster, semen ziziphi spinosae, fructus alpiniae oxyphyllae mixing are extracted with water；
Step 2: by Semen Lablab Album, Chinese yam, Poria cocos, dark plum, finger citron sliced, malt, jujube, dried longan pulp, mulberries, hawthorn, radish
Son is mixed with the extracting solution of step 1 and the dregs of a decoction, is extracted with water, is obtained extracting solution.
Preparation method 2:
It takes bulk pharmaceutical chemicals to mix in proportion, is extracted with water, obtain extracting solution.
It takes the extracting solution of preparation method 1.2 to be separately added into customary adjuvant and is prepared into children's drink.
Trial effect:
Prepare preparation children's drink respectively by both the above method
20 children of trier, the age between 6-15 years old, the trier usually not strong of appetite
Trial method: guarantor for hired help child prepared by two kinds of distinct methods is given to 10 drinking of children on probation, noon, evening respectively
Each one bottle, 125ml/ bottles, try out a week.Trial effect is paid a return visit in the form of questionnaire, the results are shown in Table 2.
The trial effect for children's drink that the different preparation methods of table 2 obtain
| Product efficacy | It is in good taste | Appetite improves | Adverse reaction |
| Preparation method 1 is efficient | 90% | 90% | 0 |
| Preparation method 2 is efficient | 80% | 60% | 0 |
The result shows that: the effect of children's drink effect prepared by preparation method 1 will be apparently higher than the children of the preparation of preparation method 2
Drink.
Embodiment
Embodiment 1
A kind of drink for treating apositia of children, is prepared as follows:
Bulk pharmaceutical chemicals composition: Semen Lablab Album 4g, Chinese yam 2g, Poria cocos 4g, dark plum 1g, oyster 1g, finger citron sliced 1g, malt 1g, wild jujube
Benevolence 4g, jujube 1g, dried longan pulp 2g, fructus alpiniae oxyphyllae 2g, mulberries 2g, hawthorn 2g, radish seed 2g；
Auxiliary material composition: white granulated sugar 260g, sodium carboxymethylcellulose 0.29g, citric acid 2.9g, sodium citrate 0.87g, essence
2.32g；
Preparation method:
Step 1: taking oyster, semen ziziphi spinosae, fructus alpiniae oxyphyllae in proportion, crush, add 10 times of water, after impregnating 2 hours, be heated to reflux and mention
Take half an hour；
Step 2: taking Semen Lablab Album, Chinese yam, Poria cocos, dark plum, finger citron sliced, malt, jujube, dried longan pulp, mulberries, mountain in proportion
Short, bristly hair or beard, radish seed add 10 times of water, and after impregnating 2 hours, the extracting solution and the dregs of a decoction obtained after water extracts with step 1 is mixed, and continue to add
Circumfluence distillation twice, 2 hours every time, filters, combined extract；
Step 3: the extracting solution that step 2 is obtained adds water to be settled to crude drug amount and reaches 1%；
Step 4: clarified solution is obtained by filtration using supercentrifuge in the good medical fluid of constant volume；
Step 5: being proportionally added into auxiliary material, cross 1.0um filtering with microporous membrane；
Step 6: using pasteurization handle, it is filling to get.
Specification: every bottle of 125ml
Usage and dosage: each primary in the morning, afternoon and evening, each 125ml
Embodiment 2
A kind of drink for treating apositia of children, is prepared as follows:
Bulk pharmaceutical chemicals composition: Semen Lablab Album 3g, Chinese yam 10g, Poria cocos 3g, dark plum 8g, oyster 2g, finger citron sliced 8g, malt 2g, wild jujube
Benevolence 15g, jujube 1g, dried longan pulp 8g, fructus alpiniae oxyphyllae 1g, mulberries 8g, hawthorn 1g, radish seed 10g；
Auxiliary material composition: white granulated sugar 200g, sodium carboxymethylcellulose 1g, citric acid 1g, sodium citrate 1.5g, crystal grape are fragrant
Smart 1g；
Preparation method:
Step 1: oyster, semen ziziphi spinosae, fructus alpiniae oxyphyllae are taken in proportion, is crushed, and 12 times of water are added, after impregnating 4 hours, ultrasonic extraction half
A hour；
Step 2: taking Semen Lablab Album, Chinese yam, Poria cocos, dark plum, finger citron sliced, malt, jujube, dried longan pulp, mulberries, mountain in proportion
Short, bristly hair or beard, radish seed add 12 times of water, and after impregnating 4 hours, the extracting solution and the dregs of a decoction obtained after water extracts with step 1 is mixed, and continues to surpass
Sound extracts twice, and 1.5 hours every time, filtration, combined extract；
Step 3: the extracting solution that step 2 is obtained adds water to be settled to crude drug amount and reaches 2%；
Step 4: the good medical fluid of constant volume is obtained into clarified solution using diatomite filter circulating filtration；
Step 5: being proportionally added into auxiliary material, cross 1.0um filtering with microporous membrane；
Step 6: using pasteurization handle, it is filling to get.
Specification: every bottle of 125ml
Usage and dosage: each primary in the morning, afternoon and evening, each 125ml
Embodiment 3
A kind of drink for treating apositia of children, is prepared as follows:
Bulk pharmaceutical chemicals composition: Semen Lablab Album 15g, Chinese yam 1g, Poria cocos 15g, dark plum 1g, oyster 8g, finger citron sliced 1g, malt 8g, acid
Jujube kernel 3g, jujube 8g, dried longan pulp 1g, fructus alpiniae oxyphyllae 8g, mulberries 1g, hawthorn 8g, radish seed 1g；
Auxiliary material composition: white granulated sugar 300g, sodium carboxymethylcellulose 0.1g, citric acid 10g, sodium citrate 0.5g, strawberry are fragrant
Smart 10g；
Preparation method:
Step 1: taking oyster, semen ziziphi spinosae, fructus alpiniae oxyphyllae in proportion, crush, add 8 times of water, after impregnating 3 hours, be heated to reflux and take
Half an hour；
Step 2: taking Semen Lablab Album, Chinese yam, Poria cocos, dark plum, finger citron sliced, malt, jujube, dried longan pulp, mulberries, mountain in proportion
Short, bristly hair or beard, radish seed add 8 times of water, and after impregnating 3 hours, the extracting solution and the dregs of a decoction obtained after water extracts with step 1 is mixed, and diacolation mentions
It takes 12 hours, filters, combined extract；
Step 3: the extracting solution that step 2 is obtained adds water to be settled to crude drug amount and reaches 3%；
Step 4: clarified solution is obtained by filtration using supercentrifuge in the good medical fluid of constant volume；
Step 5: being proportionally added into auxiliary material, cross 1.0um filtering with microporous membrane；
Step 6: using pasteurization handle, it is filling to get.
Specification: every bottle of 125ml
Usage and dosage: each primary in the morning, afternoon and evening, each 125ml.
Embodiment 4
A kind of drink for treating apositia of children, is prepared as follows:
Bulk pharmaceutical chemicals composition: Semen Lablab Album 8g, Chinese yam 2g, Poria cocos 8g, dark plum 2g, oyster 4g, finger citron sliced 1g, malt 4g, wild jujube
Benevolence 2g, jujube 4g, dried longan pulp 2g, fructus alpiniae oxyphyllae 4g, mulberries 1g, hawthorn 4g, radish seed 3g；
Auxiliary material composition: white granulated sugar 240g, sodium carboxymethylcellulose 0.5g, citric acid 2g, sodium citrate 1g, strawberry essence
2g；
Preparation method:
Step 1: taking oyster, semen ziziphi spinosae, fructus alpiniae oxyphyllae in proportion, crush, add 8 times of water, after impregnating 3 hours, be heated to reflux and take
Half an hour；
Step 2: taking Semen Lablab Album, Chinese yam, Poria cocos, dark plum, finger citron sliced, malt, jujube, dried longan pulp, mulberries, mountain in proportion
Short, bristly hair or beard, radish seed add 8 times of water, and after impregnating 3 hours, the extracting solution and the dregs of a decoction obtained after water extracts with step 1 is mixed, and diacolation mentions
It takes 12 hours, filters, combined extract；
Step 3: the extracting solution that step 2 is obtained adds water to be settled to crude drug amount and reaches 3%；
Step 4: the good medical fluid of constant volume is obtained into clarified solution using diatomite filter circulating filtration；
Step 5: being proportionally added into auxiliary material, cross 1.0um filtering with microporous membrane；
Step 6: using pasteurization handle, it is filling to get.
Specification: every bottle of 125ml
Usage and dosage: each primary in the morning, afternoon and evening, each 125ml
Embodiment 5
A kind of drink for treating apositia of children, is prepared as follows:
Bulk pharmaceutical chemicals composition: Semen Lablab Album 4g, Chinese yam 5g, Poria cocos 3g, dark plum 5g, oyster 6g, finger citron sliced 2g, malt 8g, wild jujube
Benevolence 3g, jujube 6g, dried longan pulp 7g, fructus alpiniae oxyphyllae 2g, mulberries 2g, hawthorn 5g, radish seed 5g；
Auxiliary material composition: white granulated sugar 270g, sodium carboxymethylcellulose 0.2g, citric acid 5g, sodium citrate 0.5g, strawberry essence
5g；
Preparation method:
Step 1: taking oyster, semen ziziphi spinosae, fructus alpiniae oxyphyllae in proportion, crush, add 8 times of water, after impregnating 3 hours, be heated to reflux and take
Half an hour；
Step 2: taking Semen Lablab Album, Chinese yam, Poria cocos, dark plum, finger citron sliced, malt, jujube, dried longan pulp, mulberries, mountain in proportion
Short, bristly hair or beard, radish seed add 8 times of water, and after impregnating 3 hours, the extracting solution and the dregs of a decoction obtained after water extracts with step 1 is mixed, and diacolation mentions
It takes 12 hours, filters, combined extract；
Step 3: the extracting solution that step 2 is obtained adds water to be settled to crude drug amount and reaches 3%；
Step 4: the good medical fluid of constant volume obtains clarified solution using high speed centrifugation machine filter；
Step 5: being proportionally added into auxiliary material, cross 1.0um filtering with microporous membrane；
Step 6: using pasteurization handle, it is filling to get.
Specification: every bottle of 125ml
Usage and dosage: each primary in the morning, afternoon and evening, each 125ml
Embodiment 6
A kind of Chinese medicine composition for treating apositia of children, is prepared as follows:
Bulk pharmaceutical chemicals composition: Semen Lablab Album 5g, Chinese yam 7g, Poria cocos 5g, dark plum 6g, oyster 3g, finger citron sliced 6g, malt 3g, wild jujube
Benevolence 12g, jujube 2g, dried longan pulp 6g, fructus alpiniae oxyphyllae 2g, mulberries 6g, hawthorn 1g, radish seed 7g；
Preparation method: taking bulk pharmaceutical chemicals in proportion, adds 12 times of ultrasonic extractions twice, and 1.5 hours every time, filtering, merging filtrate,
Add water to be adjusted to crude drug amount and reaches 1%；Clarified solution is obtained using diatomite filter circulating filtration；Adding water to relative density is
The clear cream of 1.06 (50~60 DEG C) is added auxiliary material, oral solution is made.
Embodiment 7
A kind of Chinese medicine composition for treating apositia of children, is prepared as follows:
Bulk pharmaceutical chemicals composition: Semen Lablab Album 12g, Chinese yam 3g, Poria cocos 12g, dark plum 3g, oyster 6g, finger citron sliced 3g, malt 6g, acid
Jujube kernel 5g, jujube 6g, dried longan pulp 3g, fructus alpiniae oxyphyllae 6g, mulberries 3g, hawthorn 6g, radish seed 3g；
Preparation method:
Bulk pharmaceutical chemicals are taken in proportion, add 10 times of water reflux twice, and 1.5 hours every time, combined extract was concentrated under reduced pressure, obtains dense
Contracting liquid B；Concentrate A, B are mixed, are dried under reduced pressure, fine powder is ground into, customary adjuvant is added, is mixed；Dry-pressing granulation, tabletting, i.e.,
?.
Embodiment 8
A kind of drink for treating apositia of children, is prepared as follows:
Bulk pharmaceutical chemicals composition: Semen Lablab Album 4g, Chinese yam 2g, Poria cocos 4g, dark plum 1g, oyster 1g, finger citron sliced 1g, malt 1g, wild jujube
Benevolence 4g, jujube 1g, dried longan pulp 2g, fructus alpiniae oxyphyllae 2g, mulberries 2g, hawthorn 2g, radish seed 2g；
Preparation method:
Bulk pharmaceutical chemicals are taken in proportion, 12 times of water is added to decoct twice, and 2 hours every time, combined extract was concentrated under reduced pressure, must be concentrated
Liquid B；Concentrate A, B are mixed, are dried under reduced pressure, fine powder is ground into, auxiliary material is added, is mixed；Dry-pressing granulation to get.
Effect experiment:
180 children of trier, 3-6 years old, 6-10 years old, 11-15 years old each 60 people was divided into three groups, and every group respectively includes 3-6
Year, 6-10 years old, 11-15 years old each 20 people.Three groups of triers use the product of embodiment 1,2,3 respectively.Children on probation are usually partially thin,
Appetite is not strong, excessive internal heat constipation, easily sick.
Test method: issuing trier for children's drink prepared by embodiment 1-3 at random, and each one bottle in the morning, afternoon and evening, 125ml/
Bottle tries out a week.Trial effect is paid a return visit in the form of questionnaire.Trial effect such as the following table 3:
The trial effect of 3 embodiment 1-3 product of table
| 1 product of embodiment | 3-6 years old children/people | 6-10 years old children/people | 11-15 years old children/people | It is efficient |
| Immunity enhancing | 17 | 16 | 17 | 83.3% |
| Appetite increased | 18 | 15 | 17 | 83.3% |
| Stool improves | 16 | 18 | 15 | 81.7% |
| It is alive | 16 | 16 | 16 | 80.0% |
| Total effective rate | 83.75% | 81.25% | 78.75 | 81.25% |
| 2 product of embodiment | 3-6 years old children/people | 6-10 years old children/people | 11-15 years old children/people | It is efficient |
| Immunity enhancing | 18 | 17 | 16 | 85% |
| Appetite increased | 16 | 16 | 15 | 78.3% |
| Stool improves | 17 | 16 | 17 | 83.3% |
| It is alive | 16 | 18 | 16 | 83.3% |
| Total effective rate | 83.75% | 83.75% | 80% | 82.5% |
| 3 product of embodiment | 3-6 years old children/people | 6-10 years old children/people | 11-15 years old children/people | It is efficient |
| Immunity enhancing | 18 | 18 | 16 | 83.3% |
| Appetite increased | 16 | 17 | 18 | 81.6% |
| Stool improves | 17 | 16 | 17 | 83.3% |
| It is alive | 16 | 16 | 17 | 81.6% |
| Total effective rate | 83.75% | 83.75% | 85% | 82.5% |
Conclusion: the present invention is suitable for children taking, has and puts on weight, and improves immunization programs for children power, and stomach strengthening and digestion promoting is invigorated
And other effects.
Claims (9)
1. a kind of Chinese medicine composition for treating apositia of children, which is characterized in that in parts by weight, the traditional Chinese medicinal composition raw materials
Composition are as follows:
3-15 parts of Semen Lablab Album, 1-10 parts of Chinese yam, 3-15 parts of Poria cocos, 1-8 parts of dark plum, 1-8 parts of oyster, 1-8 parts of finger citron sliced, malt 1-
8 parts, 3-15 parts of semen ziziphi spinosae, 1-8 parts of jujube, 1-8 parts of dried longan pulp, 1-8 parts of fructus alpiniae oxyphyllae, 1-8 parts of mulberries, 1-8 parts of hawthorn, radish seed
1-10 parts.
2. Chinese medicine composition as described in claim 1, which is characterized in that in parts by weight, the traditional Chinese medicinal composition raw materials group
Become:
3-12 parts of Semen Lablab Album, 1-7 parts of Chinese yam, 3-12 parts of Poria cocos, 1-6 parts of dark plum, 1-6 parts of oyster, 1-6 parts of finger citron sliced, malt 1-6
Part, 3-12 parts of semen ziziphi spinosae, 1-6 parts of jujube, 1-6 parts of dried longan pulp, 1-6 parts of fructus alpiniae oxyphyllae, 1-6 parts of mulberries, 1-6 parts of hawthorn, radish seed
1-7 parts.
3. Chinese medicine composition as claimed in claim 2, which is characterized in that in parts by weight, the traditional Chinese medicinal composition raw materials group
Become:
3-8 parts of Semen Lablab Album, 1-5 parts of Chinese yam, 3-8 parts of Poria cocos, 1-4 parts of dark plum, 1-4 parts of oyster, 1-4 parts of finger citron sliced, malt 1-4
Part, 3-8 parts of semen ziziphi spinosae, 1-4 parts of jujube, 1-4 parts of dried longan pulp, 1-4 parts of fructus alpiniae oxyphyllae, 1-4 parts of mulberries, 1-4 parts of hawthorn, radish seed 1-
5 parts.
4. Chinese medicine composition as claimed in claim 3, which is characterized in that in parts by weight, the traditional Chinese medicinal composition raw materials group
Become:
4 parts of Semen Lablab Album, 2 parts of Chinese yam, 4 parts of Poria cocos, 1 part of dark plum, 1 part of oyster, 1 part of finger citron sliced, 1 part of malt, semen ziziphi spinosae 4, jujube 1
Part, 2 parts of dried longan pulp, 2 parts of fructus alpiniae oxyphyllae, 2 parts of mulberries, 2 parts of hawthorn, 2 parts of radish seed.
5. the Chinese medicine composition as described in claim any one of 1-4, which is characterized in that the composition is prepared into according to a conventional method
Health beverages, oral solution, granule, tablet, capsule, powder.
6. the preparation method of Chinese medicine composition as described in claim any one of 1-4, which is characterized in that the system of the Chinese medicine composition
Preparation Method includes:
Step 1: oyster, semen ziziphi spinosae, fructus alpiniae oxyphyllae mixing are extracted with water；
Step 2: Semen Lablab Album, Chinese yam, Poria cocos, dark plum, finger citron sliced, malt, jujube, dried longan pulp, mulberries, hawthorn, radish seed and step
Rapid 1 extracting solution obtained after water extracts and dregs of a decoction mixing, continue to be extracted with water, obtain extracting solution, be concentrated under reduced pressure to get.
7. preparation method as claimed in claim 6, which is characterized in that extracting method described in steps 1 and 2 is to decoct extract, flow back
One or more of extraction, soak extraction, ultrasonic extraction or seepage pressure effects mode；The extraction time is 2-10 hours, is mentioned
Taking number is 1-3 times.
8. Chinese medicine composition is in the health care product or drug of preparation treatment apositia of children as described in claim any one of 1-4
Using.
9. a kind of health beverages for treating apositia of children, which is characterized in that the health beverages are prepared as follows:
In parts by weight, raw material forms: 3-15 parts of Semen Lablab Album, 1-10 parts of Chinese yam, 3-15 parts of Poria cocos, 1-8 parts of dark plum, oyster 1-8
Part, 1-8 parts of finger citron sliced, 1-8 parts of malt, 3-15 parts of semen ziziphi spinosae, 1-8 parts of jujube, 1-8 parts of dried longan pulp, 1-8 parts of fructus alpiniae oxyphyllae, mulberries
1-8 parts, 1-8 parts of hawthorn, 1-10 parts of radish seed；
Auxiliary material composition: 200-300 parts of white granulated sugar, 0.1-1 parts of sodium carboxymethylcellulose, 1-10 parts of citric acid, sodium citrate 0.5-
1.5 parts, 1-10 parts of essence；
Preparation method:
Step 1: oyster, semen ziziphi spinosae, fructus alpiniae oxyphyllae mixing are extracted with water；
Step 2: Semen Lablab Album, Chinese yam, Poria cocos, dark plum, finger citron sliced, malt, jujube, dried longan pulp, mulberries, hawthorn, radish seed and step
Rapid 1 extracting solution obtained after water extracts and dregs of a decoction mixing, continue to be extracted with water, obtain extracting solution；
Step 3: the extracting solution that step 2 is obtained adds water to be settled to crude drug amount 1-5%, and filtering takes filtrate；
Step 4: be proportionally added into auxiliary material, filtering to get.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106938027A (en) * | 2017-02-27 | 2017-07-11 | 胡奖荣 | Treat the medicine of apositia |
| CN108904694A (en) * | 2018-07-25 | 2018-11-30 | 太和县三九药业有限公司 | It is a kind of for improving immune oyster Chinese yam particle and preparation method thereof |
| CN111972598A (en) * | 2019-12-31 | 2020-11-24 | 钟祥亿源生物科技有限公司 | A nutritional food for invigorating middle warmer and qi |
| CN114748593B (en) * | 2022-05-17 | 2023-08-29 | 栗明峰 | Medicine and food homologous twenty-ingredient fructus alpiniae oxyphyllae sea buckthorn liquid and preparation method thereof |
| CN114748576B (en) * | 2022-05-17 | 2023-08-25 | 栗明峰 | Twenty-ingredient radix pseudostellariae sea buckthorn paste with homology of medicine and food and preparation method thereof |
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