CN106265914A - A kind of for preventing and treating because of high temperature, the high humidity Chinese medicine composition causing chicken disease and preparation method thereof - Google Patents
A kind of for preventing and treating because of high temperature, the high humidity Chinese medicine composition causing chicken disease and preparation method thereof Download PDFInfo
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- CN106265914A CN106265914A CN201610790057.5A CN201610790057A CN106265914A CN 106265914 A CN106265914 A CN 106265914A CN 201610790057 A CN201610790057 A CN 201610790057A CN 106265914 A CN106265914 A CN 106265914A
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- radix bupleuri
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/233—Bupleurum
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Abstract
The present invention relates to a kind of for preventing and treating because of high temperature, the high humidity Chinese medicine composition causing chicken disease and preparation method thereof, described Chinese medicine composition is made up of the raw material of following weight portion: Radix Bupleuri 100～900 parts, Radix Scutellariae 100～900 parts.The disease that Chinese medicine composition of the present invention can prevent and treat chicken high temperature, high humidity causes, for alleviating high temperature, chicken mass-sending heat that high humidity causes, lassitude, it is feasible that appetite declines.Additionally, clinical trial also demonstrates that Chinese medicine composition of the present invention preventing and treating chicken high temperature, high humidity cause disease, for alleviating high temperature, chicken mass-sending heat that high humidity causes, lassitude, it is effective that appetite declines.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition and preparation method thereof, particularly relate to a kind of preventing and treating chicken because of high temperature, high humidity
The Chinese medicine composition of the disease caused, belongs to fowl practical technique field.
Background technology
All can there is persistence high temperature, high humidity weather annual summer in China's most area, owing to chicken does not has a sweat gland, and entirely
Body is coated to feather, mainly by respiratory system heat radiation and regulation body temperature.If external environment epidemic disaster is too high, chicken will be made
Body heat radiation difficulty, internal metabolism and physiological disorders, badly influence the feed intake of chicken, Reproduction performance, feedstuff
Utilization rate, and may result in chicken mortality at short notice, carry out heavy losses to poultry industrial belt.At present, along with scale, intensive
Change, high-density breeding pattern universal and developing rapidly, the environmental factors such as high temperature, high humidity is more and more aobvious on the impact of aquaculture
Write, cause the biggest economic loss to aquaculture.
Be used at present preventing and treating poultry high temperature, high humidity cause the medicine of disease have Chinese herbal medicine class, vitamins, electrolytes,
Antibiotics, microelement kind, organic acid and tranquilizer class etc..At present, chemicals, hormone, antibiotic in animal products
Residue problem drastically influence the health of people, along with the issuing and implementation of national nuisanceless veterinary drug usage criteria, both at home and abroad to change
Medicine, the use of antibiotic limit more and more stricter.In clinical practice, the effect of the medicine such as vitamins, electrolytes also has
Significant limitation, and Chinese medicine both can improve the productivity of chicken, again can enhancing immunity, endocrine regulation, improve the life of blood
Reason biochemical indicator, thus alleviate high temperature, untoward reaction that high humidity brings, strengthen chicken and adapt to the ability of environment, take into account nutrition simultaneously
With the dual function of medicine, have that untoward reaction is little, residual quantity is low and the advantage such as wide material sources.Therefore, Chinese medicine is being prevented and treated by height
The attention of people is increasingly caused in the disease that temperature, high humidity cause.
China also has some for the Chinese medicine preparation that the chicken heat shock that high temperature, high humidity cause is prevented and treated at present, such as grant number
The Chinese herbal and crude drugs preparations of the anti-chicken heat shock of CN101856084B, the oral liquid being made up of the raw material of following weight proportioning: Gypsum Fibrosum 2-4
Part, Radix agastaches 2-4 part, Rhizoma Atractylodis 1-3 part, Fructus Crataegi 2-4 part, Folium Pini 2-4 part, Herb Gynostemmae Pentaphylli 0.5-1.5 part, Radix Glycyrrhizae 0.5-1.5 part；Authorize
Number for CN101156917B mono-kind for preventing and treating the medicine of livestock birds heat irritability syndrome, it is prepared by the raw materials in: grey
Art 100～200, Cortex Phellodendri 50～150, Gypsum Fibrosum 50～150, Herba Pogostemonis 50～150, the Radix Aucklandiae 50～150, Radix Glycyrrhizae 30～80；Open
Number for CN102657707A mono-kind for preventing and treating the Chinese powder medicine of broiler heat stress, it is made up of (by weight following component
Meter): Flos Lonicerae 2-5 part, Herba Moslae 1-3 part, Cortex Magnoliae Officinalis 1-3 part, Fructus Forsythiae 1-2 part；Grant number is that the patent of CN103169955B is open
A kind of herbal mixture for preventing and treating chicken heat shock, comprises the component of following parts by weight: Radix Scutellariae 200-250 part, the Rhizoma Atractylodis Macrocephalae
100-150 part, Herba Commelinae 100-150 part, Radix Gentianae 60-80 part, Fructus Viticis 60-80 part, Herba Plantaginis 60-80 part, Semen Ziziphi Spinosae 40-
60 parts, compound enzymic preparation 1-2 part, vitamin C 1-2 part.But these herbal composites are respectively provided with, and Chinese herbal medicine flavour of a drug are many, quality not
Easy to control, use cost high, therefore, livestock and poultry breeding industry is badly in need of a kind of safe and effective, easy to use, quality controllable, one-tenth
This low tcm product is used for the disease preventing and treating chicken high temperature, high humidity causes.
Summary of the invention
The present invention is to overcome the deficiency in prior art, it is provided that a kind of for preventing and treating because high temperature, high humidity cause chicken disease
Sick Chinese medicine composition, described Chinese medicine composition safely and effectively, have no side effect, quality controllable, cheap, can be used for alleviating
The chicken mass-sending heat that high temperature, high humidity cause, lassitude, degradation symptom under appetite.
The present invention for achieving the above object, by the following technical solutions:
A kind of causing the Chinese medicine composition of chicken disease for preventing and treating because of high temperature, high humidity, it is by the raw material group of following weight portion
Become: Radix Bupleuri 100～900 parts, Radix Scutellariae 100～900 parts.
Above-mentioned causing the Chinese medicine composition of chicken disease for preventing and treating because of high temperature, high humidity, described Chinese medicine composition is by following heavy
The raw material composition of amount part: Radix Bupleuri 300～700 parts, Radix Scutellariae 300～700 parts.
Above-mentioned causing the Chinese medicine composition of chicken disease for preventing and treating because of high temperature, high humidity, described Chinese medicine composition is by following heavy
The raw material composition of amount part: Radix Bupleuri 500 parts, Radix Scutellariae 500 parts；Or described Chinese medicine composition is made up of the raw material of following weight portion:
Radix Bupleuri 333 parts, Radix Scutellariae 667 parts；Or described Chinese medicine composition is made up of the raw material of following weight portion: Radix Bupleuri 667 parts, Radix Scutellariae
333 parts.
Above-mentioned causing the Chinese medicine composition of chicken disease for preventing and treating because of high temperature, high humidity, the dosage form of described Chinese medicine composition is
Oral liquid, granule or powder.
A kind of method preparing Chinese medicine composition described above, described Chinese medicine composition is oral liquid, enters as follows
OK: Radix Scutellariae adds 8～15 times amount water, decocting 2～3 times, each 1 hour, collecting decoction, filtration, filtrate was adjusted pH value to 2.0, is stood
3h, leaching precipitates and is dried, obtaining Radix Scutellariae extract；Radix Bupleuri extraction by steam distillation volatile oil, redistillation obtains Radix Bupleuri volatilization
Oil extracting solution；Medicinal residues after Radix Bupleuri distillation add 8～12 times amount, soak by water 1～2 times, each 1 hour, merge Radix Bupleuri decocting liquid, filter
Cross, be concentrated into the concentrated solution of relative density 1.14～1.16 (60 DEG C), add above-mentioned Radix Scutellariae extract, Radix Bupleuri volatile oil extraction
Liquid, constant volume, filter, embedding, to obtain final product.
A kind of method preparing Chinese medicine composition described above, described Chinese medicine composition is granule, described granule
Preparation is carried out as follows: Radix Scutellariae adds 8～15 times amount water, decocts 2～3 times, each 1 hour, collecting decoction, filtration, filtrate
Adjusting pH value to 2.0, stand 3h, leaching precipitates and is dried, obtaining Radix Scutellariae extract；Radix Bupleuri extraction by steam distillation volatile oil,
Redistillation obtains Radix Bupleuri volatile oil extracting solution；Medicinal residues after Radix Bupleuri distillation add 8～12 times amount, soak by water 1～2 times, each 1 hour,
Merging Radix Bupleuri decocting liquid, filter, filtrate is concentrated in right amount, mixs homogeneously with above-mentioned Radix Scutellariae extract and appropriate amount of auxiliary materials, makes
Grain, is dried, granulate, sprays into Radix Bupleuri volatile oil extracting solution, and mixing to obtain final product.
The adjuvant of described granule can be cane sugar powder, dextrin, lactose, glucose, soluble starch, mannitol, hydroxypropyl
One or more of base starch etc..
A kind of method preparing Chinese medicine composition described above, described Chinese medicine composition is powder, and preparation is as follows
Carry out: Radix Bupleuri, Radix Scutellariae 2 taste, pulverize (herb in granule form should all be sieved by No. two pharmacopeia), sieve, mixing, to obtain final product.
A kind of Chinese medicine composition causes the application in the medicine of disease, described Chinese drug-treated group at preparation preventing and treating chicken high temperature, high humidity
Compound is upper described Chinese medicine composition.
Medicine in above-mentioned component used is commercially available product, meets the relevant regulations of " Chinese veterinary pharmacopoeia ".
Each component effect of the present invention and composition principle are as follows:
Radix Bupleuri acrid in the mouth, hardship, cold nature, return liver, gallbladder, lung meridian, there is reconciling superficies and interior, dispersing the stagnated live-QI to relieve the stagnation of QI, ascending up spleen-Qi and Yang, bring down a fever and cut
The effects such as malaria, for cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia, uterine prolapse, proctoptosis etc., mainly use
In antipyretic.Recent studies shows, Radix Bupleuri has multiple physiology biological activity, and its pharmacological action mainly includes anti-bacteria and anti-virus, solution
Heat, antiinflammatory, protect the liver, blood fat reducing, immunomodulating, convulsion etc..
Radix Scutellariae property of medicine bitter cold, returns lung, the heart, stomach, liver and gall, large intestine channel, mainly has heat clearing and damp drying, eliminating fire and detoxication, arresting bleeding and miscarriage prevention
Effect, clinic is commonly used to treat cough due to lung-heat, few sun cold and heat, conjunctival congestion and swelling pain, and heat in blood tells nosebleed, and damp and hot painful abdominal mass is vexed, jaundice, and dysentery collapses
Leakage, ulcerative carbuncle toxic swelling, frequent fetal movement etc..Recent studies shows, the pharmacotoxicological effect of Radix Scutellariae mainly includes antibiosis and antiviral functions, right
The effect of cardio-cerebrovascular, anti-allergic effects, antiinflammatory action, refrigeration function, antitumor action, antioxidation, immunity are adjusted
Joint effect etc..
Traditional Chinese veterinary medicine is thought, is in for a long time in the environment of high temperature, high humidity, and pathogenic heat easily attacks body, strongly fragrant in half table half
Between in, cause organism fever.Radix Bupleuri can rush down the exterior heat of half exterior and half interior, and Radix Scutellariae can rush down the interior-heat of half exterior and half interior；Radix Bupleuri sending up the lucid YANG,
Radix Scutellariae the turbid descending fire, two medicines are harmonious, ascending the clear and descending the turbid, mediation the exterior and the interior, treating SHAO YANG disease by mediation, the pathogenic heat of clear few sun；Radix Bupleuri is longer than again dissipating depression of QI, yellow
A kind of reed mentioned in ancient books is good at again expelling the heat-evil, and two medicines are refinforced each other, the mechanism of qi of the most adjustable liver and gall, the pathogenic heat can accumulate in letting out clearly again；Damp is easily stranded spleen, causes
Make transporting and transforming function of the spleen and stomach unable, middle burnt deficiency-distension, loss of appetite, Radix Scutellariae, while removing summer-heat interior-heat, also can dampness be amusing, the wet releasing of spleen,
Middle burnt must transport, appetite is recovered.
Chinese medicine composition preventing and treating chicken high temperature, high humidity that Radix Bupleuri of the present invention and Radix Scutellariae compatibility are made cause disease, use
In the chicken mass-sending heat alleviating high temperature, high humidity causes, lassitude, it is feasible that appetite declines.And clinical trial also demonstrates that
Chinese medicine composition preventing and treating chicken high temperature, high humidity that Radix Bupleuri of the present invention and Radix Scutellariae compatibility are made cause disease, are used for alleviating
The chicken mass-sending heat that high temperature, high humidity cause, lassitude, it is fully effective that appetite declines.
Detailed description of the invention
The present invention is further elaborated by specific examples below, but not as a limitation of the invention.
Embodiment 1
Radix Bupleuri 500g, Radix Scutellariae 500g.
Weighing raw material by weight, Radix Scutellariae adds 8～15 times amount water, decocts 2～3 times, each 1 hour, collecting decoction, filter
Crossing, filtrate adjusts pH value to 2.0, stands 3h, and leaching precipitates and is dried, obtaining Radix Scutellariae extract；Radix Bupleuri extraction by steam distillation
Volatile oil, redistillation obtains Radix Bupleuri volatile oil extracting solution；Medicinal residues after Radix Bupleuri distillation add 8～12 times amount, soak by water 1～2 times, every time
1 hour, merge Radix Bupleuri decocting liquid, filter, be concentrated into the concentrated solution of relative density 1.14～1.16 (60 DEG C), add above-mentioned Radix Scutellariae
Extract, Radix Bupleuri volatile oil extracting solution, be settled to 1000mL, filters, embedding, to obtain final product.
During use, mixed drink: every 1L water, adds this product 1mL.
Embodiment 2
Radix Bupleuri 333g, Radix Scutellariae 667g.
Weighing raw material by weight, Radix Scutellariae adds 8～15 times amount water, decocts 2～3 times, each 1 hour, collecting decoction, filter
Crossing, filtrate adjusts pH value to 2.0, stands 3h, and leaching precipitates and is dried, obtaining Radix Scutellariae extract；Radix Bupleuri extraction by steam distillation
Volatile oil, redistillation obtains Radix Bupleuri volatile oil extracting solution；Medicinal residues after Radix Bupleuri distillation add 8～12 times amount, soak by water 1～2 times, every time
1 hour, merge Radix Bupleuri decocting liquid, filter, be concentrated into the concentrated solution of relative density 1.14～1.16 (60 DEG C), add above-mentioned Radix Scutellariae
Extract, Radix Bupleuri volatile oil extracting solution, be settled to 1000mL, filters, embedding, to obtain final product.
During use, mixed drink: every 1L water, adds this product 1mL.
Embodiment 3
Radix Bupleuri 667g, Radix Scutellariae 333g.
Weighing raw material by weight, Radix Scutellariae adds 8～15 times amount water, decocts 2～3 times, each 1 hour, collecting decoction, filter
Crossing, filtrate adjusts pH value to 2.0, stands 3h, and leaching precipitates and is dried, obtaining Radix Scutellariae extract；Radix Bupleuri extraction by steam distillation
Volatile oil, redistillation obtains Radix Bupleuri volatile oil extracting solution；Medicinal residues after Radix Bupleuri distillation add 8～12 times amount, soak by water 1～2 times, every time
1 hour, merge Radix Bupleuri decocting liquid, filter, be concentrated into the concentrated solution of relative density 1.14～1.16 (60 DEG C), add above-mentioned Radix Scutellariae
Extract, Radix Bupleuri volatile oil extracting solution, be settled to 1000mL, filters, embedding, to obtain final product.
During use, mixed drink: every 1L water, adds this product 1mL.
Embodiment 4
Radix Bupleuri 500g, Radix Scutellariae 500g.
Weighing raw material by weight, Radix Scutellariae adds 8～15 times amount water, decocts 2～3 times, each 1 hour, collecting decoction, filter
Crossing, filtrate adjusts pH value to 2.0, stands 3h, and leaching precipitates and is dried, obtaining Radix Scutellariae extract；Radix Bupleuri extraction by steam distillation
Volatile oil, redistillation obtains Radix Bupleuri volatile oil extracting solution；Medicinal residues after Radix Bupleuri distillation add 8～12 times amount, soak by water 1～2 times, every time
1 hour, merging Radix Bupleuri decocting liquid, filter, filtrate is concentrated in right amount, mixs homogeneously with above-mentioned Radix Scutellariae extract and appropriate amount of auxiliary materials,
Make granule, be dried, granulate, spray into Radix Bupleuri volatile oil extracting solution, mixing, make 1000g, to obtain final product.
During use, mixed drink: every 1L water, adds this product 1g.
Embodiment 5
Radix Bupleuri 500g, Radix Scutellariae 500g.Radix Bupleuri, Radix Scutellariae 2 taste, pulverize (herb in granule form should all be sieved), mistake by No. two pharmacopeia
Sieve, mixing, to obtain final product.
During use, spice: every 1kg feedstuff, adds this product 1g.
Experimental example 1
The Chinese medicine composition that Radix Bupleuri of the present invention and Radix Scutellariae compatibility are made causes disease at preventing and treating chicken high temperature, high humidity, uses
Hot in the chicken mass-sending alleviating high temperature, high humidity causes, lassitude, the clinical effect trial that appetite declines:
1 materials and methods
1.1 test material
1.1.1 experimental animal: Ross 308 Broiler.
1.1.2 test medicine: for the bavin Huang oral liquid formulations prepared according to the embodiment of the present invention 1.
1.2 test method
1.2.1 test packet and process
The Ross 308 Broiler selecting 10 ages in days is tested, and is evenly distributed in 2 hen houses, and No. 1 hen house is test medicine bavin
Yellow oral liquid group, No. 2 hen houses are not for process matched group.Test in chickling 15 age in days formally, No. 1 hen house reaches when hen house temperature
To more than 30 DEG C, in drinking-water, when humidity reaches more than 70%, add the bavin Huang oral liquid of 1mL/L, when temperature is less than 30 DEG C, wet
Stop when degree is less than 70% adding；No. 2 hen houses in addition to whole process is without bavin Huang oral liquid, other feeding and management and feed situation
All identical with No. 1 hen house, free choice feeding and drinking-water.
Index observing and mensuration:
1. body temperature measurement and clinical sign are observed: before on-test, (i.e. 14 age in days) measures the body temperature of chicken；On-test
Measure the most again 4 times, observe the clinical sign of 2 hen house chicken groups simultaneously；
2. the mensuration of body weight: before on-test (i.e. 14 age in days) and 1 week (i.e. 21 age in days) after on-test, 2 weeks (i.e. 28
Age in days), 3 weeks (i.e. 35 ages in days) and 4 weeks (i.e. 42 age in days) time measure its body weight from No. 1 and No. 2 each 25 chickens of random crawl respectively；
3. death rate and efficiency of feed utilization: the dead of 2 hen houses of omnidistance record washes in a pan number, feedstuff addition, delivers for sale to 42 ages in days
Time calculate death rate and the efficiency of feed utilization of 2 groups of chicken groups.
2 results and analysis
2.1 clinical manifestations respectively organizing chicken group are observed
After 1 week on-test, when the temperature of two hen houses all reaches more than 31 DEG C, when humidity reaches more than 70%, respectively
Carry out repeatedly observing to the clinical sign of the chicken group of two hen houses.It was found that the mental status of test medicine group chicken group and
Search for food all significantly better than not processing matched group.The situation of test medicine group chicken group's mouth breathing is markedly less than and does not processes matched group.
The situation of change of 2.2 chicken colony temperature
The result of variations (DEG C) of table 1 Ge Zu chicken colony temperature
Note: * * represents and do not process matched group have pole significant difference (P < 0.01)；* representing and not processing matched group has significantly
Difference (P < 0.05)；Represent without * and do not process matched group difference significantly (P > 0.05).
Table 1 data show, before on-test, when temperature, the humidity of two hen houses are close, and the mean body temperature of two groups of chicken groups
Also without significant difference (P > 0.05), and the body temperature of two groups of chicken groups that random 4 times measure after on-test, test medicine group is the most aobvious
Write less than untreated control group (P < 0.01).Again show that, when hen house is in high temperature (> 30 DEG C), high humidity (> 70%) time, chicken
The test medicine bavin Huang oral liquid adding 0.1% (1mL/L) in group's drinking-water can significantly reduce the body temperature of chicken group.
The situation of change of 2.3 Ge Zu chicken colony weights
Body weight result (g) of chicken respectively organized by table 2
Note: * * represents and do not process matched group have pole significant difference (P < 0.01)；* representing and not processing matched group has significantly
Difference (P < 0.05)；Represent without * and do not process matched group difference significantly (P > 0.05).
Table 2 data show, during on-test, the body weight between two groups of chicken groups is without significant difference (P > 0.05).After on-test 1
The average weight of all (i.e. 21 age in days) test medicine group chickens does not slightly above process matched group, but there was no significant difference (P > 0.05)；
The 2nd week (i.e. 28 age in days) to (42 age in days) during off-test after on-test, the average body weight average of test medicine group chicken group
Being significantly higher than and do not process matched group (P < 0.05 or P < 0.01), when delivering for sale, the broiler of test medicine group is average than not processing matched group
Increase weight 127.56g more.
2.4 efficiency of feed utilization and the death rates respectively organizing broiler
Efficiency of feed utilization and the death rate of broiler respectively organized by table 3
Note: * * represents and do not process matched group have pole significant difference (P < 0.01)；* representing and not processing matched group has significantly
Difference (P < 0.05)；Represent without * and do not process matched group difference significantly (P > 0.05).
Table 3 data show, it is right that the average weight gain of test medicine group and average feed intake (i.e. feed consumption rate) are above not processing
Less process matched group according to group, feedstuff-meat ratio and death rate and reduce 0.083 and 0.344 respectively；Death rate pole is substantially less than not to be located
Reason matched group (P < 0.01).Prove the hot and humid feed intake of broiler, weightening finish and the efficiency of feed utilization of significantly reducing, and at drinking-water
The bavin Huang oral liquid of middle interpolation doses can significantly alleviate the heating of the hot and humid broiler caused, feed intake, weightening finish and feedstuff
The reduction of utilization rate, also can reduce the mortality rate of broiler simultaneously.
3 conclusions
Clinical test results shows, the disease that bavin Huang oral liquid of the present invention can prevent and treat chicken high temperature, high humidity causes, aobvious
Write the symptoms such as alleviation broiler heating, lassitude and lack of appetite caused by high temperature, high humidity.Recommended dose adds for whole process in drinking-water
Test medicine bavin Huang oral liquid 1mL/L.
Below it is only the preferred embodiment of the present invention, not in order to limit the present invention, those skilled in the art is come
Say, under the premise without departing from the principles of the invention, it is also possible to some improvement of making, equivalent, should be included in the present invention
Protection domain within.
Claims (8)
1. one kind causes the Chinese medicine composition of chicken disease for preventing and treating because of high temperature, high humidity, it is characterised in that described Chinese medicine composition
It is made up of the raw material of following weight portion: Radix Bupleuri 100～900 parts, Radix Scutellariae 100～900 parts.
Chinese medicine composition the most according to claim 1, it is characterised in that described Chinese medicine composition is former by following weight portion
Material composition: Radix Bupleuri 300～700 parts, Radix Scutellariae 300～700 parts.
Chinese medicine composition the most according to claim 1, it is characterised in that described Chinese medicine composition is former by following weight portion
Material composition: Radix Bupleuri 500 parts, Radix Scutellariae 500 parts；Or described Chinese medicine composition is made up of the raw material of following weight portion: Radix Bupleuri 333
Part, Radix Scutellariae 667 parts；Or described Chinese medicine composition is made up of the raw material of following weight portion: Radix Bupleuri 667 parts, Radix Scutellariae 333 parts.
4. according to the Chinese medicine composition described in claim 1,2 or 3, it is characterised in that the dosage form of described Chinese medicine composition is mouth
Take liquid, granule or powder.
5. the method preparing Chinese medicine composition as claimed in claim 4, it is characterised in that described Chinese medicine composition is oral
Liquid, is carried out as follows: Radix Scutellariae adds 8～15 times amount water, decocts 2～3 times, and each 1 hour, collecting decoction, filtration, filtrate was adjusted
PH value, to 2.0, stands 3h, and leaching precipitates and is dried, obtaining Radix Scutellariae extract；Radix Bupleuri extraction by steam distillation volatile oil, weight
Distill to obtain Radix Bupleuri volatile oil extracting solution；Medicinal residues after Radix Bupleuri distillation add 8～12 times amount, and soak by water 1～2 times, each 1 hour are closed
And Radix Bupleuri decocting liquid, filter, be concentrated into the concentrated solution of relative density 1.14～1.16 (60 DEG C), add above-mentioned Radix Scutellariae extract,
Radix Bupleuri volatile oil extracting solution, constant volume, filter, embedding, to obtain final product.
6. the method preparing Chinese medicine composition as claimed in claim 4, it is characterised in that described Chinese medicine composition is granule
Agent, the preparation of described granule is carried out as follows: Radix Scutellariae adds 8～15 times amount water, decocts 2～3 times, each 1 hour, merges
Decocting liquid, filters, and filtrate adjusts pH value to 2.0, stands 3h, and leaching precipitates and is dried, obtaining Radix Scutellariae extract；Radix Bupleuri vapor distillation
Method extracts volatile oil, and redistillation obtains Radix Bupleuri volatile oil extracting solution；Medicinal residues after Radix Bupleuri distillation add 8～12 times amount, soak by water 1～2
Secondary, each 1 hour, merging Radix Bupleuri decocting liquid, filter, filtrate is concentrated in right amount, mixes with above-mentioned Radix Scutellariae extract and appropriate amount of auxiliary materials
Close uniformly, make granule, be dried, granulate, spray into Radix Bupleuri volatile oil extracting solution, mixing, to obtain final product.
7. the method preparing Chinese medicine composition as claimed in claim 4, it is characterised in that described Chinese medicine composition is scattered
Agent, preparation is carried out as follows: Radix Bupleuri, Radix Scutellariae 2 taste, is crushed to herb in granule form and is all sieved by No. two pharmacopeia, sieves, mixed
Even, to obtain final product.
8. Chinese medicine composition is causing the application in the medicine of disease for preparing preventing and treating chicken high temperature, high humidity, and its feature exists
In, described Chinese medicine composition is the Chinese medicine composition described in claim 1-7 any one right.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109497333A (en) * | 2018-12-07 | 2019-03-22 | 沈阳农业大学 | A kind of reduction 35-45 Day-old Broiler Chickens feedstuff-meat ratio compound Chinese medicinal additive |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101176749A (en) * | 2006-11-12 | 2008-05-14 | 黑龙江大学 | Chaihuang freeze dried injection and preparation method thereof |
| CN104127491A (en) * | 2014-07-29 | 2014-11-05 | 成都乾坤动物药业有限公司 | Pharmaceutical composition with fever relieving effect and preparation method and application thereof |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101176749A (en) * | 2006-11-12 | 2008-05-14 | 黑龙江大学 | Chaihuang freeze dried injection and preparation method thereof |
| CN104127491A (en) * | 2014-07-29 | 2014-11-05 | 成都乾坤动物药业有限公司 | Pharmaceutical composition with fever relieving effect and preparation method and application thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109497333A (en) * | 2018-12-07 | 2019-03-22 | 沈阳农业大学 | A kind of reduction 35-45 Day-old Broiler Chickens feedstuff-meat ratio compound Chinese medicinal additive |
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