CN104800686A - Medicine composition for treating overeating sequelae and preparation method and purpose of medicine composition - Google Patents
Medicine composition for treating overeating sequelae and preparation method and purpose of medicine composition Download PDFInfo
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- CN104800686A CN104800686A CN201510245975.5A CN201510245975A CN104800686A CN 104800686 A CN104800686 A CN 104800686A CN 201510245975 A CN201510245975 A CN 201510245975A CN 104800686 A CN104800686 A CN 104800686A
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Abstract
The invention discloses a medicine composition for treating overeating sequelae. The medicine composition is prepared by the following raw materials in parts by weight: 1 to 4 parts of hawthorn, 1 to 4 parts of malt, 1 to 4 parts of radish seed, 1 to 4 parts of pawpaw, and 1 to 4 parts of chicken's gizzard-membrane. The invention also discloses a preparation method and a purpose of the medicine composition. The medicine composition has the advantages that the overeating sequelae, such as abdominal distension, chest distress, thirst, dyspepsia, food retention, diarrhea and stomach distension, can be effectively released, the effective rate is high, the overeating sequelae can be treated, the compatibility is accurate, the medicine efficiency and activity are obviously better than the medicine efficiency and activity of the other medicines, and a new medicine selection is provided for clinical application.
Description
Technical field
The present invention relates to and a kind ofly treat pharmaceutical composition of eating and drinking too much at one meal sequela and its production and use.
Background technology
Eating and drinking too much at one meal is kind of a bad living habit, and it can bring a lot of harm to the health of people.There will be after eating and drinking too much at one meal dizziness, absentminded, gastrointestinal upset, uncomfortable in chest out of breath, diarrhoea or constipation, serious meeting causes acute gastroenteritis, even gastrorrhagia; Plenty of meat and fish, heavy drinking can make liver and gall overload operation, hepatocyte accelerates accretion rate, bile secretion increases, cause liver function injury, bring out cholecystitis, hepatitis patient aggravation, pancreas also can be made to secrete in a large number, and in duodenum, pressure increases, bring out acute pancreatitis, serious symptom person can cause people's unnatural death.
Therefore, the medicine that gives rise to diseases of research and development effective treatment eating and drinking too much at one meal is very necessary.
Summary of the invention
The object of the present invention is to provide and a kind ofly treat pharmaceutical composition of eating and drinking too much at one meal sequela and its production and use.
The invention provides a kind of pharmaceutical composition for the treatment of eating and drinking too much at one meal sequela, it is the preparation be prepared from by the crude drug of following weight proportion: it is the preparation be prepared from by the crude drug of following weight proportion: Fructus Crataegi 1-4 part, Fructus Hordei Germinatus 1-4 part, Semen Raphani 1-4 part, Fructus Chaenomelis 1-4 part, Endothelium Corneum Gigeriae Galli 1-4 part.
Preferably, it is the preparation be prepared from by the crude drug of following weight proportion: Fructus Crataegi 2 parts, 2 parts, Fructus Hordei Germinatus, Semen Raphani 3 parts, Fructus Chaenomelis 3 parts, Endothelium Corneum Gigeriae Galli 2 parts.
Wherein, described preparation be by the medicated powder of each crude drug, the water of crude drug or/and ethanol extraction is active component, to add in pharmacy or health product the preparation that conventional adjuvant or complementary composition are prepared from.
Further, described preparation is oral formulations.
Further, described oral liquid, granule, capsule, unguentum, pill, tablet or powder.
Present invention also offers the preparation method of aforementioned pharmaceutical compositions, it comprises the steps:
(1) each crude drug is taken by weight ratio;
(2) each crude drug directly pulverized or add water or/and after ethanol extraction, adding adjuvant conventional in pharmacy or complementary composition, be prepared into conventional preparation, obtain final product.
Present invention also offers the purposes of aforementioned pharmaceutical compositions in the medicine of preparation treatment eating and drinking too much at one meal sequela.
Eating and drinking too much at one meal sequela: the untoward reaction referring to health after eating and drinking too much at one meal, as gastrointestinal upset, uncomfortable in chest, thirsty, dyspepsia, food stagnation, flatulence, abdominal distention, stomachache, diarrhoea.
Wherein, described medicine be treatment eating and drinking too much at one meal cause abdominal distention, uncomfortable in chest, thirsty, dyspepsia, food stagnation, stomachache, diarrhoea and/or flatulence medicine.
In we, Semen Raphani helps digestion de-swelling, and for retention of food and drink, abdominal distention, stagnant dysentery, eliminating the gastrointestinal upset because eating and drinking too much at one meal causes, is our monarch drug.Hawthorn digesting stomach invigorating, auxiliary Semen Raphani alleviates the stomach damage because eating and drinking too much at one meal causes; Fructus Hordei Germinatus spleen benefiting and stimulating the appetite, promotes that spleen and stomach function recovers normal; The spleen invigorating of Endothelium Corneum Gigeriae Galli alleviating distention in middle-JIAO, promoting digestion and removing stagnation is with digest food, and three is also our ministerial drug.The removing dampness of Fructus Chaenomelis stomach function regulating is adjuvant drug.
Pharmaceutical composition of the present invention effectively can alleviate abdominal distention, uncomfortable in chest, thirsty, dyspepsia, food stagnation, stomachache, the eating and drinking too much at one meal sequela such as diarrhoea and flatulence, effective percentage is high, eating and drinking too much at one meal sequela can be treated, and compatibility is precise and appropriate, drug activity is obviously better than other flavour of a drug proportionings, and potential applicability in clinical practice is good.
Obviously, according to foregoing of the present invention, according to ordinary technical knowledge and the customary means of this area, not departing under the present invention's above-mentioned basic fundamental thought prerequisite, the amendment of other various ways, replacement or change can also be made.
The detailed description of the invention of form by the following examples, is described in further detail foregoing of the present invention again.But this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following example.All technology realized based on foregoing of the present invention all belong to scope of the present invention.
Detailed description of the invention
The preparation of embodiment 1 present composition
Get crude drug: Fructus Crataegi 2g, Fructus Hordei Germinatus 2g, Semen Raphani 3g, Fructus Chaenomelis 3g, Endothelium Corneum Gigeriae Galli 2g, make granule.
Get above-mentioned raw materials medicine, first use 75% alcohol reflux 2 times, collect alcohol extract, medicinal residues decoct with water 2 times again, merge decocting liquid, after alcohol extract is reclaimed ethanol, mix with decocting liquid, concentrated, add appropriate amount of auxiliary materials and prepare granule.
The preparation of embodiment 2 present composition
Get crude drug: Fructus Crataegi 1g, Fructus Hordei Germinatus 1g, Semen Raphani 1g, Fructus Chaenomelis 4g, Endothelium Corneum Gigeriae Galli 4g, make granule.
Get above-mentioned raw materials medicine, by each component crushed after being dried, sieve gets the medicated powder of certain particle size, makes bag tea agent or powder, every packed amount 2g after mix homogeneously.
The preparation of embodiment 3 present composition
Get crude drug: Fructus Crataegi 4g, Fructus Hordei Germinatus 4g, Semen Raphani 4g, Fructus Chaenomelis 1g, Endothelium Corneum Gigeriae Galli 1g, make granule.
Get above-mentioned raw materials medicine, decoct with water 3 times, merge decocting liquid, concentrated, add appropriate amount of auxiliary materials and prepare buccal tablet.
The preparation of embodiment 4 present composition
Get crude drug: Fructus Crataegi 3g, Fructus Hordei Germinatus 1g, Semen Raphani 4g, Fructus Chaenomelis 2g, Endothelium Corneum Gigeriae Galli 2g, make unguentum.
Get above-mentioned raw materials medicine, decoct with water 3 times, merge decocting liquid, filter, be concentrated into thick paste, add appropriate amount of auxiliary materials, be prepared into unguentum.
Beneficial effect of the present invention is proved below by way of concrete pharmacodynamics test.
Test example 1 pharmaceutical composition of the present invention is to the therapeutical effect of eating and drinking too much at one meal sequela
Eating and drinking too much at one meal and sequela thereof accept standard for medical treatment: accepting patient 131 example for medical treatment, is eating and drinking too much at one meal and sequela thereof through hospital diagnosis, and patients symptomatic comprises gastrointestinal upset, uncomfortable in chest, thirsty, dyspepsia, food stagnation, flatulence, abdominal distention, stomachache, diarrhoea.
Therapeutic Method: use granule prepared by embodiment 1, often wrap 10g, take after mixing it with water with 100ml boiled water, every day twice, every 10g granule is equivalent to crude drug 5g, treatment time is 5-10 days altogether.
Therapeutic outcome (following table is classified with same symptoms):
Table 1
Table 2
Table 3
Table 4
Table 5
Experimental result illustrates, pharmaceutical composition of the present invention effectively can alleviate the eating and drinking too much at one meal sequela such as abdominal distention, uncomfortable in chest, thirsty, dyspepsia, food stagnation, stomachache, diarrhoea and flatulence, and effective percentage is high, can treat eating and drinking too much at one meal sequela, and potential applicability in clinical practice is good.
The investigation of test example 2 prescription flavour of a drug of the present invention
The present invention, at the research initial stage, in order to obtain effect stability, the better prescription of therapeutic effect, investigates drug regimen, through comparing, finally determines that prescription of the present invention is for the best side, specifically compares data as follows:
(1) contrast groups 1: Fructus Crataegi 2 parts of Fructus Hordei Germinatus 2 portions of Fructus Chaenomeliss 3 parts of Endothelium Corneum Gigeriae Galli 2 parts
Prepare granule according to embodiment 1 method, daily 2 times, each 10g, boiled water is taken after mixing it with water.
The granule (prepared by embodiment 1) of contrast groups 1 and of the present invention group is treated 30 people respectively, and it the results are shown in following table:
Table 6 pharmaceutical composition and contrast groups are on the impact of patient's abdominal distention symptom
(2) contrast groups 2: Fructus Crataegi 2 parts of Fructus Hordei Germinatus 2 parts of Semen Raphanis 3 parts of Endothelium Corneum Gigeriae Galli 2 parts.Prepare granule according to embodiment 1 method, daily 2 times, each 10g, boiled water is taken after mixing it with water.
The granule (prepared by embodiment 1) of contrast groups 2 and of the present invention group is treated 30 people respectively, and it the results are shown in following table:
The impact of table 7 pharmaceutical composition and contrast groups symptom uncomfortable in chest on patient, thirsty
(3) contrast groups 3: Fructus Crataegi 2 parts of Semen Raphanis 3 portions of Fructus Chaenomeliss 3 parts of Endothelium Corneum Gigeriae Galli 2 parts.Prepare granule according to embodiment 1 method, daily 2 times, each 10g, boiled water is taken after mixing it with water.
The granule (prepared by embodiment 1) of contrast groups 3 and of the present invention group is treated 30 people respectively, and it the results are shown in following table:
Table 8 pharmaceutical composition and contrast groups is bad on people digest, the impact of food stagnation symptom
(4) contrast groups 4: Fructus Hordei Germinatus 2 parts of Semen Raphanis 3 portions of Fructus Chaenomeliss 3 parts of Endothelium Corneum Gigeriae Galli 2 parts.Prepare granule according to embodiment 1 method, daily 2 times, each 10g, boiled water is taken after mixing it with water.
The granule (prepared by embodiment 1) of contrast groups 4 and of the present invention group is treated 30 people respectively, and it the results are shown in following table:
Table 9 pharmaceutical composition and contrast groups are on the impact of patient's stomachache, symptom of diarrhea
(5) contrast groups 5: Fructus Crataegi 2 parts of Fructus Hordei Germinatus 2 parts of Semen Raphanis 3 portions of Fructus Chaenomeliss 3 parts.Prepare granule according to embodiment 1 method, daily 2 times, each 10g, boiled water is taken after mixing it with water.
The granule (prepared by embodiment 1) of contrast groups 5 and of the present invention group is treated 30 people respectively, and it the results are shown in following table:
Table 10 pharmaceutical composition and contrast groups are on the impact of patient's flatulence symptom
From the above results, although the prescription flavour of a drug of contrast groups 1 ~ 5 are comparatively similar to the present invention, but, under identical dosage, the remissive treatment successful of drug regimen of the present invention to abdominal distention, uncomfortable in chest, thirsty, dyspepsia, food stagnation, stomachache, the eating and drinking too much at one meal sequela such as diarrhoea and flatulence is better than contrast groups 1 ~ 5, this just shows, the flavour of a drug compatibility of pharmaceutical composition of the present invention is precise and appropriate, and each flavour of a drug are indispensable.
Claims (8)
1. treat a pharmaceutical composition for eating and drinking too much at one meal sequela, it is characterized in that: it is the preparation be prepared from by the crude drug of following weight proportion: Fructus Crataegi 1-4 part, Fructus Hordei Germinatus 1-4 part, Semen Raphani 1-4 part, Fructus Chaenomelis 1-4 part, Endothelium Corneum Gigeriae Galli 1-4 part.
2. pharmaceutical composition according to claim 1, is characterized in that: it is the preparation be prepared from by the crude drug of following weight proportion: Fructus Crataegi 2 parts, 2 parts, Fructus Hordei Germinatus, Semen Raphani 3 parts, Fructus Chaenomelis 3 parts, Endothelium Corneum Gigeriae Galli 2 parts.
3. the pharmaceutical composition according to claim 1 or 2 any one, it is characterized in that: it be by the medicated powder of each crude drug, the water of crude drug or/and ethanol extraction is active component, to add in pharmacy or health product the preparation that conventional adjuvant or complementary composition are prepared from.
4. the pharmaceutical composition according to claims 1 to 3 any one, is characterized in that: described preparation is oral formulations.
5. pharmaceutical composition according to claim 4, is characterized in that: described oral formulations is granule, oral liquid, capsule, unguentum, pill, tablet or powder.
6. the preparation method of pharmaceutical composition described in Claims 1 to 5 any one, is characterized in that: it comprises the steps:
(1) each crude drug is taken by weight ratio;
(2) each crude drug directly pulverized or add water or/and after ethanol extraction, adding adjuvant conventional in pharmacy or complementary composition, be prepared into conventional preparation.
7. the purposes of pharmaceutical composition described in Claims 1 to 5 any one in the medicine of preparation treatment eating and drinking too much at one meal sequela.
8. purposes according to claim 7, is characterized in that: described medicine be treatment eating and drinking too much at one meal cause abdominal distention, uncomfortable in chest, thirsty, dyspepsia, food stagnation, stomachache, diarrhoea and/or flatulence medicine.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106177643A (en) * | 2016-08-05 | 2016-12-07 | 谭元生 | The Chinese prescription of a kind of relieving dyspepsia and goods thereof |
Citations (2)
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| RU2461387C2 (en) * | 2010-08-16 | 2012-09-20 | Федеральное государственное образовательное учреждение высшего профессионального образования "Горский государственный аграрный университет" | Method of treating dyspepsia in calves |
| CN102698141A (en) * | 2012-03-20 | 2012-10-03 | 章崇芝 | Traditional Chinese medicinal composition for treating dyspepsia |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2461387C2 (en) * | 2010-08-16 | 2012-09-20 | Федеральное государственное образовательное учреждение высшего профессионального образования "Горский государственный аграрный университет" | Method of treating dyspepsia in calves |
| CN102698141A (en) * | 2012-03-20 | 2012-10-03 | 章崇芝 | Traditional Chinese medicinal composition for treating dyspepsia |
Non-Patent Citations (3)
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| 周浓等: "《中药养生学》", 31 January 2015, 中国中医药出版社 * |
| 张明: "《做自己的营养医生》", 30 June 2014, 天津科学技术出版社 * |
| 李莉: "《家庭生活万事通》", 31 January 2005, 内蒙古人民出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106177643A (en) * | 2016-08-05 | 2016-12-07 | 谭元生 | The Chinese prescription of a kind of relieving dyspepsia and goods thereof |
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