CN104800686B - A kind of pharmaceutical composition for treating sequelae of eating and drinking immoderately and its preparation method and application - Google Patents
A kind of pharmaceutical composition for treating sequelae of eating and drinking immoderately and its preparation method and application Download PDFInfo
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- CN104800686B CN104800686B CN201510245975.5A CN201510245975A CN104800686B CN 104800686 B CN104800686 B CN 104800686B CN 201510245975 A CN201510245975 A CN 201510245975A CN 104800686 B CN104800686 B CN 104800686B
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Abstract
The invention discloses a kind of pharmaceutical composition for treating sequelae of eating and drinking immoderately, it is the preparation being prepared by the bulk pharmaceutical chemicals of following weight proportion：14 parts of hawthorn, 14 parts of malt, 14 parts of radish seed, 14 parts of pawpaw, 14 parts of the membrane of a chicken's gizzard.The invention also discloses the preparation method and purposes of foregoing pharmaceutical composition.Pharmaceutical composition of the present invention can effectively alleviate the sequelae of eating and drinking immoderately such as abdominal distension, uncomfortable in chest, thirsty, indigestion, having indigestion, abdominal pain, diarrhea and gasteremphraxis, high efficiency, sequelae of eating and drinking immoderately can be treated, and compatibility is precise and appropriate, drug activity is substantially better than other flavour of a drug proportioning, and a kind of new medicament selection is provided for clinic.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition for treating sequelae of eating and drinking immoderately and its preparation method and application.
Background technology
It is kind of a undesirable habits and customs to eat and drink immoderately, and the health care belt that it can give people much endangers.It can go out after eating and drinking immoderately
Existing dizzy, absent-minded, digestive discomfort, out of breath, diarrhea uncomfortable in chest or constipation, it is serious to cause acute gastroenteritis, even
Gastrorrhagia；Plenty of meat and fish, heavy drinking can make liver and gall overload operation, and liver cell accelerates accretion rate, and choleresis increase, makes
Into hepatic disorder, cholecystitis, hepatitis patient aggravation are induced, can also pancreas is largely secreted, pressure increases in duodenum
Height, induces acute pancreatitis, and severe person can cause people's unnatural death.
Therefore, it is very necessary effectively to treat the medicine eaten and drunk immoderately and given rise to diseases for research and development.
The content of the invention
It is an object of the invention to provide a kind of pharmaceutical composition and preparation method thereof for treating sequelae of eating and drinking immoderately and
Purposes.
The present invention provides a kind of pharmaceutical composition for treating sequelae of eating and drinking immoderately, it is by the original of following weight proportion
The preparation that material medicine is prepared：It is the preparation being prepared by the bulk pharmaceutical chemicals of following weight proportion：1-4 parts of hawthorn, malt 1-4
Part, 1-4 parts of radish seed, 1-4 parts of pawpaw, 1-4 parts of the membrane of a chicken's gizzard.
Preferably, it is the preparation being prepared by the bulk pharmaceutical chemicals of following weight proportion：2 parts of hawthorn, 2 parts of malt, radish
3 parts of son, 3 parts of pawpaw, 2 parts of the membrane of a chicken's gizzard.
Wherein, it by the medicinal powder of each bulk pharmaceutical chemicals, the water of bulk pharmaceutical chemicals or/and ethanol extract is active ingredient that the preparation, which is,
The preparation being prepared plus common auxiliary material in pharmacy or health products or complementary component.
Further, the preparation is oral formulations.
Further, the oral liquid, granule, capsule, paste, pill, tablet or powder.
Present invention also offers the preparation method of aforementioned pharmaceutical compositions, it includes the following steps：
(1) each bulk pharmaceutical chemicals are weighed by weight ratio；
(2) by each bulk pharmaceutical chemicals directly crush or add water or/and ethanol extraction after, add pharmacy in common auxiliary material or
Complementary component, is prepared into common preparation, to obtain the final product.
Present invention also offers purposes of the aforementioned pharmaceutical compositions in the medicine treated and eat and drink immoderately sequelae is prepared.
Eat and drink immoderately sequelae：Refer to the adverse reaction of body after eating and drinking immoderately, as digestive discomfort, it is uncomfortable in chest, thirsty, disappear
Change bad, having indigestion, gasteremphraxis, abdominal distension, abdominal pain, diarrhea.
Wherein, the medicine is to treat eat and drink immoderately caused abdominal distension, uncomfortable in chest, thirsty, indigestion, having indigestion, abdominal pain, abdomen
Rush down and/or the medicine of gasteremphraxis.
Radish seed help digestion and eliminate flatulence in we, for retention of food and drink, abdominal distention, stagnate rush down dysentery, and elimination is drawn because eating and drinking immoderately
The digestive discomfort risen, for our monarch drug in a prescription.Hawthorn digesting stomach invigorating, auxiliary radish seed mitigate the stomach caused by eating and drinking immoderately and damage；
Malt spleen benefiting and stimulating the appetite, promotes spleen and stomach function to recover normal；The wide middle invigorating the spleen of the membrane of a chicken's gizzard, to digest food, three is simultaneously promoting digestion and removing indigestion
Our ministerial drug.Pawpaw stomach dampness elimination, is adjutant.
Pharmaceutical composition of the present invention can effectively alleviate abdominal distension, uncomfortable in chest, thirsty, indigestion, having indigestion, abdominal pain, diarrhea and
Gasteremphraxis etc. is eaten and drunk immoderately sequelae, and high efficiency, can treat sequelae of eating and drinking immoderately, and compatibility is precise and appropriate, and drug activity is obvious
Matched better than other flavour of a drug, potential applicability in clinical practice is good.
Obviously, the above according to the present invention, according to the ordinary technical knowledge and customary means of this area, is not departing from
Under the premise of the above-mentioned basic fundamental thought of the present invention, the modification, replacement or change of other diversified forms can also be made.
The embodiment of form by the following examples, remakes further specifically the above of the present invention
It is bright.But the scope that this should not be interpreted as to the above-mentioned theme of the present invention is only limitted to following example.It is all to be based on the above of the present invention
The technology realized belongs to the scope of the present invention.
Embodiment
The preparation of 1 present composition of embodiment
Take bulk pharmaceutical chemicals：Hawthorn 2g, malt 2g, radish seed 3g, pawpaw 3g, the membrane of a chicken's gizzard 2g, are made granule.
Above-mentioned raw materials medicine is taken, is first extracted 2 times with 75% alcohol reflux, collects alcohol extract, the dregs of a decoction add water decoction 2 times, close
And decocting liquid, after alcohol extract is recycled ethanol, mix, concentrate with decocting liquid, add appropriate amount of auxiliary materials and prepare granule.
The preparation of 2 present composition of embodiment
Take bulk pharmaceutical chemicals：Hawthorn 1g, malt 1g, radish seed 1g, pawpaw 4g, the membrane of a chicken's gizzard 4g, are made granule.
Above-mentioned raw materials medicine is taken, by each component crushed after being dried, sieve takes the medicinal powder of certain particle size, and bag bubble is made after mixing
Medicinal tea or powder, per packed amount 2g.
The preparation of 3 present composition of embodiment
Take bulk pharmaceutical chemicals：Hawthorn 4g, malt 4g, radish seed 4g, pawpaw 1g, the membrane of a chicken's gizzard 1g, are made granule.
Above-mentioned raw materials medicine is taken, is added water to cook 3 times, merges decocting liquid, concentration, adds appropriate amount of auxiliary materials and prepare buccal tablet.
The preparation of 4 present composition of embodiment
Take bulk pharmaceutical chemicals：Hawthorn 3g, malt 1g, radish seed 4g, pawpaw 2g, the membrane of a chicken's gizzard 2g, are made paste.
Above-mentioned raw materials medicine is taken, is added water to cook 3 times, merges decocting liquid, filtering, is concentrated into thick paste, adds appropriate amount of auxiliary materials, prepares
Paste making agent.
Beneficial effects of the present invention are proved below by way of specific pharmacodynamics test.
Therapeutic effect of 1 pharmaceutical composition of the present invention of test example to sequelae of eating and drinking immoderately
Eat and drink immoderately and its sequelae accepts standard for medical treatment：Accept patient 131 for medical treatment, be to eat and drink immoderately and lose thereafter through hospital diagnosis
Disease, patient symptom include digestive discomfort, uncomfortable in chest, thirsty, indigestion, having indigestion, gasteremphraxis, abdominal distension, abdominal pain, diarrhea.
Treatment method：The granule prepared using embodiment 1, often wraps 10g, is taken after mixing it with water with 100ml boiling water, twice daily, often
10g granules are equivalent to crude drug 5g, common 5-10 days for the treatment of time.
Treatment results (following table is classified with same symptoms)：
Table 1
Table 2
Table 3
Table 4
Table 5
The experiment results show that pharmaceutical composition of the present invention can effectively alleviate abdominal distension, uncomfortable in chest, thirsty, indigestion, product
Food, abdominal pain, diarrhea and gasteremphraxis etc. are eaten and drunk immoderately sequelae, and high efficiency, can treat sequelae of eating and drinking immoderately, before clinical practice
Scape is good.
The investigation of the prescription flavour of a drug of the present invention of test example 2
The present invention research initial stage, the more preferable prescription of effect stability, therapeutic effect, carries out drug regimen in order to obtain
Investigate, through comparing, finally determine prescription of the present invention as optimal side, specific relatively data are as follows：
(1) contrast groups 1：2 parts of hawthorn, 2 parts of malt, 3 parts of pawpaw, 2 parts of the membrane of a chicken's gizzard
Granule is prepared according to 1 method of embodiment, daily 2 times, each 10g, boiling water is taken after mixing it with water.
The granule (prepared by embodiment 1) that contrast groups 1 are organized with the present invention is treated into 30 people respectively, the result is shown in following table：
The influence of 6 pharmaceutical composition of table and contrast groups to patient's abdominal distension symptom
(2) contrast groups 2：2 parts of hawthorn, 2 parts of malt, 3 parts of radish seed, 2 parts of the membrane of a chicken's gizzard.According to the preparation of 1 method of embodiment
Granula, daily 2 times, each 10g, boiling water is taken after mixing it with water.
The granule (prepared by embodiment 1) that contrast groups 2 are organized with the present invention is treated into 30 people respectively, the result is shown in following table：
The influence of 7 pharmaceutical composition of table and contrast groups symptom uncomfortable in chest to patient, thirsty
(3) contrast groups 3：2 parts of hawthorn, 3 parts of radish seed, 3 parts of pawpaw, 2 parts of the membrane of a chicken's gizzard.According to the preparation of 1 method of embodiment
Granula, daily 2 times, each 10g, boiling water is taken after mixing it with water.
The granule (prepared by embodiment 1) that contrast groups 3 are organized with the present invention is treated into 30 people respectively, the result is shown in following table：
8 pharmaceutical composition of table and contrast groups are bad to people digest, the influence of having indigestion symptom
(4) contrast groups 4：2 parts of malt, 3 parts of radish seed, 3 parts of pawpaw, 2 parts of the membrane of a chicken's gizzard.According to the preparation of 1 method of embodiment
Granula, daily 2 times, each 10g, boiling water is taken after mixing it with water.
The granule (prepared by embodiment 1) that contrast groups 4 are organized with the present invention is treated into 30 people respectively, the result is shown in following table：
The influence of 9 pharmaceutical composition of table and contrast groups to patient's abdominal pain, symptom of diarrhea
(5) contrast groups 5：2 portions of hawthorn, 2 portions of malt, 3 portions of radish seed, 3 parts of pawpaw.Particle is prepared according to 1 method of embodiment
Agent, daily 2 times, each 10g, boiling water is taken after mixing it with water.
The granule (prepared by embodiment 1) that contrast groups 5 are organized with the present invention is treated into 30 people respectively, the result is shown in following table：
The influence of 10 pharmaceutical composition of table and contrast groups to patient's gasteremphraxis symptom
From the above results, although the prescription flavour of a drug of contrast groups 1~5 and the present invention are more similar, identical
Under dosage, drug regimen of the present invention is to crapulences such as abdominal distension, uncomfortable in chest, thirsty, indigestion, having indigestion, abdominal pain, diarrhea and gasteremphraxis
The remissive treatment positive effect of gluttony sequelae is better than contrast groups 1~5, this is indicated that, the flavour of a drug of pharmaceutical composition of the present invention are matched somebody with somebody
5 is precise and appropriate, and each flavour of a drug are indispensable.
Claims (7)
- A kind of 1. pharmaceutical composition for treating sequelae of eating and drinking immoderately, it is characterised in that：It is by the raw material of following weight proportion The preparation that medicine is prepared：2 parts of hawthorn, 2 parts of malt, 3 parts of radish seed, 3 parts of pawpaw, 2 parts of the membrane of a chicken's gizzard.
- 2. pharmaceutical composition according to claim 1, it is characterised in that：It is medicinal powder, the bulk pharmaceutical chemicals by each bulk pharmaceutical chemicals Water or/and ethanol extract are active ingredient, the preparation being prepared plus common auxiliary material in pharmacy or complementary component.
- 3. pharmaceutical composition according to claim 1 or 2, it is characterised in that：The preparation is oral formulations.
- 4. pharmaceutical composition according to claim 3, it is characterised in that：The oral formulations are granule, oral liquid, glue Wafer, paste, pill, tablet or powder.
- 5. the preparation method of claim 1 ~ 4 any one described pharmaceutical composition, it is characterised in that：It includes the following steps：（1）Each bulk pharmaceutical chemicals are weighed by weight ratio；（2）By each bulk pharmaceutical chemicals directly crush or add water or/and ethanol extraction after, add pharmacy in common auxiliary material or auxiliary Property component, is prepared into common preparation.
- 6. use of the claim 1 ~ 4 any one described pharmaceutical composition in the medicine treated and eat and drink immoderately sequelae is prepared On the way.
- 7. purposes according to claim 6, it is characterised in that：The medicine is to treat eat and drink immoderately caused abdominal distension, chest Vexed, thirsty, indigestion, having indigestion, abdominal pain, the medicine of diarrhea and/or gasteremphraxis.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| RU2461387C2 (en) * | 2010-08-16 | 2012-09-20 | Федеральное государственное образовательное учреждение высшего профессионального образования "Горский государственный аграрный университет" | Method of treating dyspepsia in calves |
| CN102698141A (en) * | 2012-03-20 | 2012-10-03 | 章崇芝 | Traditional Chinese medicinal composition for treating dyspepsia |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2461387C2 (en) * | 2010-08-16 | 2012-09-20 | Федеральное государственное образовательное учреждение высшего профессионального образования "Горский государственный аграрный университет" | Method of treating dyspepsia in calves |
| CN102698141A (en) * | 2012-03-20 | 2012-10-03 | 章崇芝 | Traditional Chinese medicinal composition for treating dyspepsia |
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