CN102389562A - Traditional Chinese medicine composition for treating indigestion in children - Google Patents
Traditional Chinese medicine composition for treating indigestion in children Download PDFInfo
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- CN102389562A CN102389562A CN2011103767878A CN201110376787A CN102389562A CN 102389562 A CN102389562 A CN 102389562A CN 2011103767878 A CN2011103767878 A CN 2011103767878A CN 201110376787 A CN201110376787 A CN 201110376787A CN 102389562 A CN102389562 A CN 102389562A
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Abstract
The invention discloses a traditional Chinese medicine composition for treating indigestion in children, and the traditional Chinese medicine composition is prepared by the following raw material medicines by weight: 110-130 parts of fructus polygoni orientalis, 50-70 parts of hawthorn, 50-70 parts of stir-fried malt, 50-70 parts of chicken gizzard membrane, 50-70 parts of medicated leaven, 25-35 parts of pericarpium citri reticulatae, 25-35 parts of betel nuts, 50-70 parts of bighead atractylodes rhizome, 110-130 parts of white hyacinth beans, 50-70 parts of jujube, and 25-35 parts of ginger. The traditional Chinese medicine composition of the invention is prepared by pure traditional Chinese medicines, has no toxic or side effect, low treatment cost, significant curative effect, and stable effect, is safe and reliable, is applicable to patients with spleen deficiency with dyspepsia such as indigestion in children, anorexia, infantile malnutrition, and the like which have symptoms of anorexia, abdominal distension, stomachache, emaciation with sallow complexion, and the like, can recuperate sick children fundamentally, reaches the purpose of simultaneous treatment of principal and subordinate symptoms, promotes health growth and development of children, and is worthy to be popularized and applied.
Description
Technical field
The invention belongs to medical technical field, be specifically related to a kind of Chinese medicine composition of treating infantile malnutrition.
Background technology
Digestive system disease comprises Alimentary organic and functional disease.Children's's internal organs are tender and lovely, and shape gas does not fill, and life is flourishing, blastoprolepsis; Nutritional requirement is big, but pediatric diet does not know that from joint food is not known hungry full, particular about food; The absorption of snacks, plump food, father and mother heavily mend gently and disappear in addition, put undue emphasis on nutritious tonifying; So that surpass normally fortune function of the spleen and stomach in children, thereby cause the digestant for baby malabsorption, so the spleen and stomach in children disease is the most common.The traditional Chinese medical science can combine the etiology and pathogenesis of children's's physiology, pathological characteristic and the spleen-stomach disease, uses the middle supplement that disappears, and disappears to mend bonded Therapeutic Method; Reach the effect of function of spleen and stomach regulating; Eliminate body to the obstacle that nutrient digestion absorbs, fundamentally treat infantile malnutrition, anorexia; Infantile malnutrition disease promotes children ' s healthy growth to grow.
Summary of the invention
Technical problem to be solved by this invention is the deficiency to above-mentioned prior art, provides a kind of safe and reliable, has no side effect the Chinese medicine composition of treatment infantile malnutrition evident in efficacy.This Chinese medicine composition can fundamentally be nursed one's health spleen and stomach function, is benefit to disappear, and disappears to mend to combine; To reach the spleen strengthening and damp drying, QI invigorating and blood producing, the effect of eliminating stagnated food and killing intestinal worms; Increase Abwehrkraft des Koepers; The defence exopathogen, thus infantile malnutrition, anorexia, infantile malnutrition disease fundamentally treated, promote children ' s healthy growth to grow.
For solving the problems of the technologies described above, the technical scheme that the present invention adopts is: a kind of Chinese medicine composition of treating infantile malnutrition is characterized in that this Chinese medicine composition is processed by following bulk drugs: 110～130 parts of Fructus Polygoni Orientaliss; 50～70 parts of Fructus Crataegis, 50～70 parts of Fructus Hordei Germinatus (parched)s, 50～70 parts of Endothelium Corneum Gigeriae Galli, 50～70 parts of Massa Medicata Fermentatas; 25～35 parts of Pericarpium Citri Reticulataes, 25～35 parts of Semen Arecaes, 50～70 parts of the Rhizoma Atractylodis Macrocephalaes; 110～130 parts of Semen Lablab Albums, 50～70 parts in Fructus Jujubae, 25～35 parts in Rhizoma Zingiberis Recens.
Above-mentioned a kind of Chinese medicine composition of treating infantile malnutrition, this Chinese medicine composition is processed by following bulk drugs: 115～125 parts of Fructus Polygoni Orientaliss, 55～65 parts of Fructus Crataegis; 55～65 parts of Fructus Hordei Germinatus (parched)s, 55～65 parts of Endothelium Corneum Gigeriae Galli, 55～65 parts of Massa Medicata Fermentatas; 28～32 parts of Pericarpium Citri Reticulataes, 28～32 parts of Semen Arecaes, 55～65 parts of the Rhizoma Atractylodis Macrocephalaes; 115～125 parts of Semen Lablab Albums, 55～65 parts in Fructus Jujubae, 28～32 parts in Rhizoma Zingiberis Recens.
Above-mentioned a kind of Chinese medicine composition of treating infantile malnutrition, this Chinese medicine composition is processed by following bulk drugs: 120 parts of Fructus Polygoni Orientaliss, 60 parts of Fructus Crataegis; 60 parts of Fructus Hordei Germinatus (parched)s, 60 parts of Endothelium Corneum Gigeriae Galli, 60 parts of Massa Medicata Fermentatas; 30 parts of Pericarpium Citri Reticulataes, 30 parts of Semen Arecaes, 60 parts of the Rhizoma Atractylodis Macrocephalaes; 120 parts of Semen Lablab Albums, 60 parts in Fructus Jujubae, 30 parts in Rhizoma Zingiberis Recens.
Above-mentioned a kind of Chinese medicine composition of treating infantile malnutrition, this Chinese medicine composition is processed by following bulk drugs: 125 parts of Fructus Polygoni Orientaliss, 65 parts of Fructus Crataegis; 65 parts of Fructus Hordei Germinatus (parched)s, 65 parts of Endothelium Corneum Gigeriae Galli, 65 parts of Massa Medicata Fermentatas; 32 parts of Pericarpium Citri Reticulataes, 32 parts of Semen Arecaes, 65 parts of the Rhizoma Atractylodis Macrocephalaes; 125 parts of Semen Lablab Albums, 65 parts in Fructus Jujubae, 32 parts in Rhizoma Zingiberis Recens.
Above-mentioned a kind of Chinese medicine composition of treating infantile malnutrition, this Chinese medicine composition is processed by following bulk drugs: 115 parts of Fructus Polygoni Orientaliss, 55 parts of Fructus Crataegis; 55 parts of Fructus Hordei Germinatus (parched)s, 55 parts of Endothelium Corneum Gigeriae Galli, 55 parts of Massa Medicata Fermentatas; 28 parts of Pericarpium Citri Reticulataes, 28 parts of Semen Arecaes, 55 parts of the Rhizoma Atractylodis Macrocephalaes; 115 parts of Semen Lablab Albums, 55 parts in Fructus Jujubae, 28 parts in Rhizoma Zingiberis Recens.
Above-mentioned a kind of Chinese medicine composition of treating infantile malnutrition, the dosage form of said Chinese medicine composition is tablet, capsule, oral solutions, granule, powder, pill or syrup.
The preparation technology of tablet of the present invention: take by weighing the crude drug of respectively distinguishing the flavor of by weight; Ten flavor medical materials except that Endothelium Corneum Gigeriae Galli are added 10 times of water gagings decoctions 2 hours, filter; In filterable medicinal residues, add Endothelium Corneum Gigeriae Galli, add 8 times of water gagings then and decocted 1.5 hours, filter merging filtrate; It is 1.05～1.10 (50 ℃) that filtrating is concentrated into relative density, adds ethanol and makes and contain alcohol amount and reach 60%～70%, leaves standstill cold preservation 48 hours; Getting the supernatant decompression recycling ethanol, is 1.25～1.28 (50 ℃) with supernatant concentration to relative density then, adds ethanol again and makes and contain alcohol amount and reach 80%～85%; Leave standstill, getting supernatant decompression recycling ethanol to relative density is 1.28～1.32 (50 ℃), adopts conventional marumerization or wet granulation process to process granule; Tabletting promptly gets tablet, and every is equivalent to crude drug 3g.Usage and dosage: oral, one-year-old with 1 next time, one-year-old to five years old one time 2,2～3 times on the one; More than five years old, one time 2,3～4 times on the one.
The preparation technology of capsule of the present invention: take by weighing the crude drug of respectively distinguishing the flavor of by weight; Ten flavor medical materials except that Endothelium Corneum Gigeriae Galli are added 10 times of water gagings decoctions 2 hours, filter; In filterable medicinal residues, add Endothelium Corneum Gigeriae Galli, add 8 times of water gagings then and decocted 1.5 hours, filter merging filtrate; It is 1.05～1.10 (50 ℃) that filtrating is concentrated into relative density, adds ethanol and makes and contain alcohol amount and reach 60%～70%, leaves standstill cold preservation 48 hours; Getting the supernatant decompression recycling ethanol, is 1.25～1.28 (50 ℃) with supernatant concentration to relative density then, adds ethanol again and makes and contain alcohol amount and reach 80%～85%; Leave standstill, getting supernatant decompression recycling ethanol to relative density is 1.28～1.32 (50 ℃), adopts conventional marumerization or wet granulation process to process granule; Be packed into capsule, promptly get capsule, every capsules is equivalent to crude drug 3g.Usage and dosage: oral, one-year-old with 1 next time, one-year-old to five years old one time 2,2～3 times on the one; More than five years old, one time 2,3～4 times on the one.
The preparation technology of oral solutions of the present invention: take by weighing the crude drug of respectively distinguishing the flavor of by weight; Ten flavor medical materials except that Endothelium Corneum Gigeriae Galli are added 10 times of water gagings decoctions 2 hours, filter; In filterable medicinal residues, add Endothelium Corneum Gigeriae Galli, add 8 times of water gagings then and decocted 1.5 hours, filter merging filtrate; It is 1.05～1.10 (50 ℃) that filtrating is concentrated into relative density, adds ethanol and makes and contain alcohol amount and reach 60%～70%, leaves standstill cold preservation 48 hours, gets the supernatant decompression recycling ethanol; Be 1.25～1.28 (50 ℃) with supernatant concentration to relative density then, add ethanol again and make and contain alcohol amount and reach 80%～85% that leave standstill, getting supernatant decompression recycling ethanol to relative density is 1.28～1.32 (50 ℃); Add water and stir in right amount, filter, filtrating adds simple syrup and sodium benzoate, and adjust pH to 4.0～6.0; Add water, stir, filter embedding; Sterilization promptly gets oral solutions, every bottle of 10mL, and every bottleneck clothes liquid is equivalent to crude drug 6g.Usage and dosage: oral, one-year-old with 5mL next time, one-year-old to five years old one time 10mL, 2～3 times on the one; More than five years old, a 10mL, 3～4 times on the one.
The preparation technology of granule of the present invention: take by weighing the crude drug of respectively distinguishing the flavor of by weight; Ten flavor medical materials except that Endothelium Corneum Gigeriae Galli are added 10 times of water gagings decoctions 2 hours, filter; In filterable medicinal residues, add Endothelium Corneum Gigeriae Galli, add 8 times of water gagings then and decocted 1.5 hours, filter merging filtrate; It is 1.05～1.10 (50 ℃) that filtrating is concentrated into relative density, adds ethanol and makes and contain alcohol amount and reach 60%～70%, leaves standstill cold preservation 48 hours, gets the supernatant decompression recycling ethanol; Be 1.25～1.28 (50 ℃) with supernatant concentration to relative density then, add ethanol again and make and contain alcohol amount and reach 80%～85%, leave standstill; Getting supernatant decompression recycling ethanol to relative density is 1.28～1.32 (50 ℃), adopts conventional marumerization or wet granulation process to process granule, packing; Promptly get granule, every bag of 5g, every bag is equivalent to crude drug 6g.Usage and dosage: oral, one-year-old with 2.5g next time, one-year-old to five years old one time 5g, 2～3 times on the one; More than five years old, a 5g, 3～4 times on the one.
The preparation technology of powder of the present invention: take by weighing the crude drug of respectively distinguishing the flavor of by weight; Ten flavor medical materials except that Endothelium Corneum Gigeriae Galli are added 10 times of water gagings decoctions 2 hours, filter; In filterable medicinal residues, add Endothelium Corneum Gigeriae Galli, add 8 times of water gagings then and decocted 1.5 hours, filter; Merging filtrate, it is 1.05～1.10 (50 ℃) that filtrating is concentrated into relative density, adds ethanol and makes and contain alcohol amount and reach 60%～70%; Leaving standstill cold preservation 48 hours, and got the supernatant decompression recycling ethanol, is 1.25～1.28 (50 ℃) with supernatant concentration to relative density then; Add ethanol again and make and contain alcohol amount and reach 80%～85%, leave standstill, getting supernatant decompression recycling ethanol to relative density is 1.28～1.32 (50 ℃); Method according to routine system powder is processed powder, every bag of 5g, and every bag is equivalent to crude drug 6g.Usage and dosage: oral, one-year-old with 2.5g next time, one-year-old to five years old one time 5g, 2～3 times on the one; More than five years old, a 5g, 3～4 times on the one.
The preparation technology of pill of the present invention: take by weighing the crude drug of respectively distinguishing the flavor of by weight; Ten flavor medical materials except that Endothelium Corneum Gigeriae Galli are added 10 times of water gagings decoctions 2 hours, filter; In filterable medicinal residues, add Endothelium Corneum Gigeriae Galli, add 8 times of water gagings then and decocted 1.5 hours, filter merging filtrate; It is 1.05～1.10 (50 ℃) that filtrating is concentrated into relative density, adds ethanol and makes and contain alcohol amount and reach 60%～70%, leaves standstill cold preservation 48 hours; Getting the supernatant decompression recycling ethanol, is 1.25～1.28 (50 ℃) with supernatant concentration to relative density then, adds ethanol again and makes and contain alcohol amount and reach 80%～85%; Leave standstill, getting supernatant decompression recycling ethanol to relative density is 1.28～1.32 (50 ℃), processes soft material according to the method for conventional pill agent; Use the pellet processing machine pill, promptly get pill, every ball is equivalent to crude drug 3g.Usage and dosage: oral, one-year-old with 1 ball next time, one-year-old to five years old one time 2 balls, 2～3 times on the one; More than five years old, one time 2 ball, 3～4 times on the one.
The preparation technology of syrup of the present invention: take by weighing the crude drug of respectively distinguishing the flavor of by weight; Ten flavor medical materials except that Endothelium Corneum Gigeriae Galli are added 10 times of water gagings decoctions 2 hours, filter; In filterable medicinal residues, add Endothelium Corneum Gigeriae Galli, add 8 times of water gagings then and decocted 1.5 hours, filter; Merging filtrate, it is 1.05～1.10 (50 ℃) that filtrating is concentrated into relative density, adds ethanol and makes and contain alcohol amount and reach 60%～70%; Leaving standstill cold preservation 48 hours, and got the supernatant decompression recycling ethanol, is 1.25～1.28 (50 ℃) with supernatant concentration to relative density then; Add ethanol again and make and contain alcohol amount and reach 80%～85%, leave standstill, getting supernatant decompression recycling ethanol to relative density is 1.28～1.32 (50 ℃); Process syrup according to the syrupy method of routine system, every 10mL syrup is equivalent to crude drug 6g.Usage and dosage: oral, one-year-old with 5mL next time, one-year-old to five years old one time 10mL, 2～3 times on the one; More than five years old, a 10mL, 3～4 times on the one.
Said weight portion can be weight metering units such as gram, two, jin, kilogram, ton.
Chinese medicine composition of the present invention is a monarch drug with Fructus Polygoni Orientalis and Fructus Crataegi, and Fructus Polygoni Orientalis has the merit of invigorating spleen to remove dampness, repercussive eliminating stagnation; Fructus Crataegi has promoting digestion and invigorating the stomach, the merit of circulation of qi promoting dissipating blood stasis.Ministerial drug is Fructus Hordei Germinatus (parched), Endothelium Corneum Gigeriae Galli, Massa Medicata Fermentata, Pericarpium Citri Reticulatae, Semen Arecae, Fructus Hordei Germinatus (parched) ability promote qi circulation digestion promoting, and specially the rapid digestion of food thing is stagnant; Endothelium Corneum Gigeriae Galli ability promoting digestion and invigorating the stomach; But the Massa Medicata Fermentata strengthening the spleen to promote digestion, activating QI to eliminate phlegm; Pericarpium Citri Reticulatae has the merit of appetizing in regulating QI and lowering the adverseness, the accent, drying dampness to eliminate phlegm; Semen Arecae has killing insect and eliminating accumulation, the merit of the capable water of sending down the abnormal ascending QI, and five medicines all can be assisted monarch drug to strengthen curative effect.Add the Rhizoma Atractylodis Macrocephalae, Semen Lablab Album and Rhizoma Zingiberis Recens in addition, but Rhizoma Atractylodis Macrocephalae invigorating the spleen and benefiting QI, the dampness diuretic; Semen Lablab Album can invigorating the spleen for eliminating dampness and in relieve summer heat; Rhizoma Zingiberis Recens is hot to help the taste yang-energy except that the taste cold-evil, but appetite stimulator; Three medicines share both can assist monarch drug with strengthening the spleen to promote digestion, can prevent the too anti-imapirment of the spleen and stomach of its food stagnation removing again; Chinese medicine composition of the present invention also adds Fructus Jujubae, and both priming was gone into taste two warps, again can invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind and hundred medicines.
The present invention is complete, and the side has the spleen strengthening and damp drying, QI invigorating removing food stagnancy.Be used for the insufficiency of the spleen food stagnation persons of accompanying of genus such as infantile malnutrition, anorexia, infantile consumption, disease is seen indigestion and loss of appetite anorexia, abdominal distention stomachache, diseases such as emaciation and sallow complexion; Can fundamentally nurse one's health spleen and stomach function, be benefit to disappear, and disappears to mend to combine; To reach the spleen strengthening and damp drying, QI invigorating and blood producing, the effect of eliminating stagnated food and killing intestinal worms; Increase Abwehrkraft des Koepers, the defence exopathogen, thus promote children ' s healthy growth to grow.
The present invention compared with prior art has the following advantages:
1, the present invention adopts pure Chinese medicine preparation, has no side effect, and uses through clinical 422 routine patients, and total effective rate is 100%.
2, to treat cost low, evident in efficacy in the present invention, and effect stability is safe and reliable; Be used for infantile malnutrition, anorexia, genus such as infantile consumption are insufficiency of the spleen to accompany food stagnation person, and disease is seen indigestion and loss of appetite anorexia; Abdominal distention stomachache, diseases such as emaciation and sallow complexion can fundamentally be nursed one's health infant; Reach the purpose of treating both the principal and secondary aspects of a disease, promote children ' s healthy growth to grow, be worthy of popularization.
The specific embodiment
Embodiment 1
The Chinese medicine composition of present embodiment is processed by following bulk drugs: Fructus Polygoni Orientalis 120g, Fructus Crataegi 60g, Fructus Hordei Germinatus (parched) 60g, Endothelium Corneum Gigeriae Galli 60g, Massa Medicata Fermentata 60g, Pericarpium Citri Reticulatae 30g, Semen Arecae 30g, Rhizoma Atractylodis Macrocephalae 60g, Semen Lablab Album 120g, Fructus Jujubae 60g, Rhizoma Zingiberis Recens 30g.
The preparation technology of present embodiment Chinese medicine composition is: take by weighing the crude drug of respectively distinguishing the flavor of by weight; Ten flavor medical materials except that Endothelium Corneum Gigeriae Galli are added 10 times of water gagings decoctions 2 hours, filter; In filterable medicinal residues, add Endothelium Corneum Gigeriae Galli, add 8 times of water gagings then and decocted 1.5 hours, filter merging filtrate; It is 1.05～1.10 (50 ℃) that filtrating is concentrated into relative density, adds ethanol and makes and contain alcohol amount and reach 60%～70%, leaves standstill cold preservation 48 hours; Getting the supernatant decompression recycling ethanol, is 1.25～1.28 (50 ℃) with supernatant concentration to relative density then, adds ethanol again and makes and contain alcohol amount and reach 80%～85%; Leave standstill, getting supernatant decompression recycling ethanol to relative density is 1.28～1.32 (50 ℃), adopts conventional marumerization or wet granulation process to process granule; Tabletting promptly gets tablet, and every is equivalent to crude drug 3g.
The usage and dosage of present embodiment Chinese medicine composition is: oral, one-year-old with 1 next time, one-year-old to five years old one time 2,2～3 times on the one; More than five years old, one time 2,3～4 times on the one.
Embodiment 2
The Chinese medicine composition of present embodiment is processed by following bulk drugs: Fructus Polygoni Orientalis 130g, Fructus Crataegi 70g, Fructus Hordei Germinatus (parched) 70g, Endothelium Corneum Gigeriae Galli 70g, Massa Medicata Fermentata 70g, Pericarpium Citri Reticulatae 35g, Semen Arecae 35g, Rhizoma Atractylodis Macrocephalae 70g, Semen Lablab Album 130g, Fructus Jujubae 70g, Rhizoma Zingiberis Recens 35g.
The preparation technology of present embodiment Chinese medicine composition is: take by weighing the crude drug of respectively distinguishing the flavor of by weight; Ten flavor medical materials except that Endothelium Corneum Gigeriae Galli are added 10 times of water gagings decoctions 2 hours, filter; In filterable medicinal residues, add Endothelium Corneum Gigeriae Galli, add 8 times of water gagings then and decocted 1.5 hours, filter merging filtrate; It is 1.05～1.10 (50 ℃) that filtrating is concentrated into relative density, adds ethanol and makes and contain alcohol amount and reach 60%～70%, leaves standstill cold preservation 48 hours; Getting the supernatant decompression recycling ethanol, is 1.25～1.28 (50 ℃) with supernatant concentration to relative density then, adds ethanol again and makes and contain alcohol amount and reach 80%～85%; Leave standstill, getting supernatant decompression recycling ethanol to relative density is 1.28～1.32 (50 ℃), adopts conventional marumerization or wet granulation process to process granule; Be packed into capsule, promptly get capsule, every capsules is equivalent to crude drug 3g.
The usage and dosage of present embodiment Chinese medicine composition is: oral, one-year-old with 1 next time, one-year-old to five years old one time 2,2～3 times on the one; More than five years old, one time 2,3～4 times on the one.
Embodiment 3
The Chinese medicine composition of present embodiment is processed by following bulk drugs: Fructus Polygoni Orientalis 110g, Fructus Crataegi 50g, Fructus Hordei Germinatus (parched) 50g, Endothelium Corneum Gigeriae Galli 50g, Massa Medicata Fermentata 50g, Pericarpium Citri Reticulatae 25g, Semen Arecae 25g, Rhizoma Atractylodis Macrocephalae 50g, Semen Lablab Album 110g, Fructus Jujubae 50g, Rhizoma Zingiberis Recens 25g.
The preparation technology of present embodiment Chinese medicine composition is: take by weighing the crude drug of respectively distinguishing the flavor of by weight; Ten flavor medical materials except that Endothelium Corneum Gigeriae Galli are added 10 times of water gagings decoctions 2 hours, filter; In filterable medicinal residues, add Endothelium Corneum Gigeriae Galli, add 8 times of water gagings then and decocted 1.5 hours, filter merging filtrate; It is 1.05～1.10 (50 ℃) that filtrating is concentrated into relative density, adds ethanol and makes and contain alcohol amount and reach 60%～70%, leaves standstill cold preservation 48 hours, gets the supernatant decompression recycling ethanol; Be 1.25～1.28 (50 ℃) with supernatant concentration to relative density then, add ethanol again and make and contain alcohol amount and reach 80%～85% that leave standstill, getting supernatant decompression recycling ethanol to relative density is 1.28～1.32 (50 ℃); Add water and stir in right amount, filter, filtrating adds simple syrup 250mL and sodium benzoate 3g, and adjust pH to 4.0～6.0; Add water to 1000mL, stir, filter embedding; Sterilization promptly gets oral solutions, every bottle of 10mL, and every bottleneck clothes liquid is equivalent to crude drug 6g.
The usage and dosage of present embodiment Chinese medicine composition is: oral, one-year-old with 5mL next time, one-year-old to five years old one time 10mL, 2～3 times on the one; More than five years old, a 10mL, 3～4 times on the one.
Embodiment 4
The Chinese medicine composition of present embodiment is processed by following bulk drugs: Fructus Polygoni Orientalis 125g, Fructus Crataegi 65g, Fructus Hordei Germinatus (parched) 65g, Endothelium Corneum Gigeriae Galli 65g, Massa Medicata Fermentata 65g, Pericarpium Citri Reticulatae 32g, Semen Arecae 32g, Rhizoma Atractylodis Macrocephalae 65g, Semen Lablab Album 125g, Fructus Jujubae 65g, Rhizoma Zingiberis Recens 32g.
The preparation technology of present embodiment Chinese medicine composition is: take by weighing the crude drug of respectively distinguishing the flavor of by weight; Ten flavor medical materials except that Endothelium Corneum Gigeriae Galli are added 10 times of water gagings decoctions 2 hours, filter; In filterable medicinal residues, add Endothelium Corneum Gigeriae Galli, add 8 times of water gagings then and decocted 1.5 hours, filter merging filtrate; It is 1.05～1.10 (50 ℃) that filtrating is concentrated into relative density, adds ethanol and makes and contain alcohol amount and reach 60%～70%, leaves standstill cold preservation 48 hours, gets the supernatant decompression recycling ethanol; Be 1.25～1.28 (50 ℃) with supernatant concentration to relative density then, add ethanol again and make and contain alcohol amount and reach 80%～85%, leave standstill; Getting supernatant decompression recycling ethanol to relative density is 1.28～1.32 (50 ℃), adopts conventional marumerization or wet granulation process to process granule, packing; Promptly get granule, every bag of 5g, every bag is equivalent to crude drug 6g.
The usage and dosage of present embodiment Chinese medicine composition is: oral, one-year-old with 2.5g next time, one-year-old to five years old one time 5g, 2～3 times on the one; More than five years old, a 5g, 3～4 times on the one.
Embodiment 5
The Chinese medicine composition of present embodiment is processed by following bulk drugs: Fructus Polygoni Orientalis 115g, Fructus Crataegi 55g, Fructus Hordei Germinatus (parched) 55g, Endothelium Corneum Gigeriae Galli 55g, Massa Medicata Fermentata 55g, Pericarpium Citri Reticulatae 28g, Semen Arecae 28g, Rhizoma Atractylodis Macrocephalae 55g, Semen Lablab Album 115g, Fructus Jujubae 55g, Rhizoma Zingiberis Recens 28g.
The preparation technology of present embodiment Chinese medicine composition is: take by weighing the crude drug of respectively distinguishing the flavor of by weight; Ten flavor medical materials except that Endothelium Corneum Gigeriae Galli are added 10 times of water gagings decoctions 2 hours, filter; In filterable medicinal residues, add Endothelium Corneum Gigeriae Galli, add 8 times of water gagings then and decocted 1.5 hours, filter; Merging filtrate, it is 1.05～1.10 (50 ℃) that filtrating is concentrated into relative density, adds ethanol and makes and contain alcohol amount and reach 60%～70%; Leaving standstill cold preservation 48 hours, and got the supernatant decompression recycling ethanol, is 1.25～1.28 (50 ℃) with supernatant concentration to relative density then; Add ethanol again and make and contain alcohol amount and reach 80%～85%, leave standstill, getting supernatant decompression recycling ethanol to relative density is 1.28～1.32 (50 ℃); Method according to routine system powder is processed powder, every bag of 5g, and every bag is equivalent to crude drug 6g.
The usage and dosage of present embodiment Chinese medicine composition is: oral, one-year-old with 1 bag next time, one-year-old to five years old one time 2 bags, 2～3 times on the one; More than five years old, one time 2 bags, 3～4 times on the one.
Embodiment 6
The Chinese medicine composition of present embodiment is processed by following bulk drugs: 120 parts of Fructus Polygoni Orientaliss, 62 parts of Fructus Crataegis, 64 parts of Fructus Hordei Germinatus (parched)s, 64 parts of Endothelium Corneum Gigeriae Galli; 62 parts of Massa Medicata Fermentatas, 30 parts of Pericarpium Citri Reticulataes, 32 parts of Semen Arecaes, 63 parts of the Rhizoma Atractylodis Macrocephalaes; 125 parts of Semen Lablab Albums, 63 parts in Fructus Jujubae, 28 parts in Rhizoma Zingiberis Recens.
The preparation technology of present embodiment Chinese medicine composition is: take by weighing the crude drug of respectively distinguishing the flavor of by weight; Ten flavor medical materials except that Endothelium Corneum Gigeriae Galli are added 10 times of water gagings decoctions 2 hours, filter; In filterable medicinal residues, add Endothelium Corneum Gigeriae Galli, add 8 times of water gagings then and decocted 1.5 hours, filter merging filtrate; It is 1.05～1.10 (50 ℃) that filtrating is concentrated into relative density, adds ethanol and makes and contain alcohol amount and reach 60%～70%, leaves standstill cold preservation 48 hours; Getting the supernatant decompression recycling ethanol, is 1.25～1.28 (50 ℃) with supernatant concentration to relative density then, adds ethanol again and makes and contain alcohol amount and reach 80%～85%; Leave standstill, getting supernatant decompression recycling ethanol to relative density is 1.28～1.32 (50 ℃), processes soft material according to the method for conventional pill agent; Use the pellet processing machine pill, promptly get pill, every ball is equivalent to crude drug 3g.
The usage and dosage of present embodiment Chinese medicine composition is: oral, one-year-old with 1 ball next time, one-year-old to five years old one time 2 balls, 2～3 times on the one; More than five years old, one time 2 ball, 3～4 times on the one.
Embodiment 7
The Chinese medicine composition of present embodiment is processed by following bulk drugs: 124 parts of Fructus Polygoni Orientaliss, 62 parts of Fructus Crataegis, 64 parts of Fructus Hordei Germinatus (parched)s, 64 parts of Endothelium Corneum Gigeriae Galli; 62 parts of Massa Medicata Fermentatas, 31 parts of Pericarpium Citri Reticulataes, 32 parts of Semen Arecaes, 63 parts of the Rhizoma Atractylodis Macrocephalaes; 125 parts of Semen Lablab Albums, 63 parts in Fructus Jujubae, 32 parts in Rhizoma Zingiberis Recens.
The preparation technology of present embodiment Chinese medicine composition is: take by weighing the crude drug of respectively distinguishing the flavor of by weight; Ten flavor medical materials except that Endothelium Corneum Gigeriae Galli are added 10 times of water gagings decoctions 2 hours, filter; In filterable medicinal residues, add Endothelium Corneum Gigeriae Galli, add 8 times of water gagings then and decocted 1.5 hours, filter; Merging filtrate, it is 1.05～1.10 (50 ℃) that filtrating is concentrated into relative density, adds ethanol and makes and contain alcohol amount and reach 60%～70%; Leaving standstill cold preservation 48 hours, and got the supernatant decompression recycling ethanol, is 1.25～1.28 (50 ℃) with supernatant concentration to relative density then; Add ethanol again and make and contain alcohol amount and reach 80%～85%, leave standstill, getting supernatant decompression recycling ethanol to relative density is 1.28～1.32 (50 ℃); Process syrup according to the syrupy method of routine system, every 10mL syrup is equivalent to crude drug 6g.
The usage and dosage of present embodiment Chinese medicine composition is: oral, one-year-old with 5mL next time, one-year-old to five years old one time 10mL, 2～3 times on the one; More than five years old, a 10mL, 3～4 times on the one.
Curative effect determinate standard:
Criterion of cure: appetite recovers normal, and spirit takes a turn for the better, and stool is normal, and General Symptoms disappears.
The produce effects standard: appetite before is clearly better, spirit, and the body card also is clearly better.
Effective standard: appetite take a favorable turn slightly, and General Symptoms alleviates to some extent.
Invalid standard: appetite spirit no change, General Symptoms does not alleviate.
General clinical data: clinical observation case 496 examples of the present invention, wherein 300 examples are organized in treatment, and spleen reinforcing removing food stagnancy oral liquid matched group 100 examples fatly must be given birth to matched group 96 examples.The treatment group is taken oral solutions of the present invention, and is one-year-old with 5mL next time, one-year-old to five years old one time 10mL, 2～3 times on the one; More than five years old, a 10mL, 3～4 times on the one, below 6 months, consumption cuts down according to the circumstance, and two weeks were a course of treatment; Spleen reinforcing removing food stagnancy oral liquid matched group is taken spleen reinforcing removing food stagnancy oral liquid, and instructions of taking is identical with oral solutions of the present invention, and two weeks were a course of treatment; Fat must give birth to matched group take fat must be living, every day 3 times, 1 years old with half bag next time, 1～3 years old one time one bag, 4～6 years old one time one bag half wrapped with last two in 7 years old, one after each meal, two weeks were a course of treatment.Three groups of general curative effects compare, and its result sees the following form:
Table 1 Comparison of therapeutic
Can find out that from table 1 treatment is organized in 300 examples, cure 286 examples, account for 95.3%, produce effects 12 examples account for 4.0%, and effective 2 examples account for 0.7%, total effective rate 100%; In spleen reinforcing removing food stagnancy oral liquid matched group 100 examples, cure 78 examples, account for 78%, produce effects 12 examples account for 12%, and effective 10 examples account for 10%, total effective rate 100%; Fat must giving birth in matched group 96 examples cured 52 examples, accounts for 54.2%, and produce effects 18 examples account for 18.7%, and effective 16 examples account for 16.7%, and invalid 10 examples account for 10.4%, total effective rate 89.6%.Treatment group and fat must be given birth to matched group relatively, and there is significant difference in curative effect, and treatment group curative effect obviously is superior to fatly must giving birth to matched group, and the treatment group is not found toxic and side effects and any untoward reaction.Treatment group and spleen reinforcing removing food stagnancy oral liquid matched group compare, and curative effect there are differences, and treatment group curative effect is superior to spleen reinforcing removing food stagnancy oral liquid matched group.
In sum, Chinese medicine composition of the present invention is superior on treatment infantile malnutrition, anorexia, infantile consumption that traditional medication is fat must give birth to and spleen reinforcing removing food stagnancy oral liquid, is the new drug of treating infantile malnutrition, anorexia, infantile malnutrition disease preferably.Chinese medicine composition of the present invention has dual regulation, and the double folder of spleen deficiency dyspepsia, folder malnutrition due to parasitic infestation, folder phlegm-damp, the stagnant blood stasis of gas enclosure are had curative effect preferably.In addition, Chinese medicine composition of the present invention is not found toxic and side effects and any untoward reaction in clinical trial, be safe and reliable.
Confirm that through clinical trial Chinese medicine composition of the present invention is evident in efficacy, safe and reliable, can fundamentally nurse one's health spleen and stomach function, be benefit to disappear; Disappearing to mend combines, to reach the spleen strengthening and damp drying, QI invigorating and blood producing; The effect of eliminating stagnated food and killing intestinal worms increases Abwehrkraft des Koepers, the defence exopathogen; Thereby fundamentally treat infantile malnutrition, anorexia, infantile malnutrition disease, promote children ' s healthy growth to grow, be worth further promotion and application.
Model case
Case 1: the Wang, the man, 10 months, anorexia 1 wheat harvesting period, with abdominal distention, it is rare to defecate, shallow complexion, body is slightly thin, and pale tongue with white fur is thick.Oral oral liquid of the present invention, every day three times, each 5mL takes medicine after the week continuously, and appetite obviously increases, and perspires and reduces, and abdominal distention alleviates, and stool every day 2～3 times, mushy stool continued to take medicine after the week, and appetite is normal, and abdominal distention disappears, and stool is normal.
Case 2: Zhang, the man, 5 years old, inappetence, appetite descends, and partial eclipse is particular about food, and is rare when doing during stool, has more than 3 years every day 3～4 times, and infant is become thin, shallow complexion, spirit still can.Oral oral liquid of the present invention, each 10mL, took medicine for two weeks continuously at every day 3 times.Diet increases, and spirit takes a turn for the better, the stool slivering, and once a day, complexion is ruddy before.
Case 3: poplar, the man, 7 years old, more than half a year since, inappetence, rare when doing during stool, hyperhidrosis, shallow complexion, hair is sparse, tired mind.Oral oral liquid of the present invention, each 10mL, took medicine for two weeks continuously at every day 4 times.Diet increases, and appetite is identical with healthy children of the same age, and stool is normal, and spirit takes a turn for the better, and has rosy cheeks.
Claims (6)
1. a Chinese medicine composition of treating infantile malnutrition is characterized in that, this Chinese medicine composition is processed by following bulk drugs: 110～130 parts of Fructus Polygoni Orientaliss, 50～70 parts of Fructus Crataegis; 50～70 parts of Fructus Hordei Germinatus (parched)s, 50～70 parts of Endothelium Corneum Gigeriae Galli, 50～70 parts of Massa Medicata Fermentatas; 25～35 parts of Pericarpium Citri Reticulataes, 25～35 parts of Semen Arecaes, 50～70 parts of the Rhizoma Atractylodis Macrocephalaes; 110～130 parts of Semen Lablab Albums, 50～70 parts in Fructus Jujubae, 25～35 parts in Rhizoma Zingiberis Recens.
2. a kind of Chinese medicine composition of treating infantile malnutrition according to claim 1 is characterized in that this Chinese medicine composition is processed by following bulk drugs: 115～125 parts of Fructus Polygoni Orientaliss, 55～65 parts of Fructus Crataegis; 55～65 parts of Fructus Hordei Germinatus (parched)s, 55～65 parts of Endothelium Corneum Gigeriae Galli, 55～65 parts of Massa Medicata Fermentatas; 28～32 parts of Pericarpium Citri Reticulataes, 28～32 parts of Semen Arecaes, 55～65 parts of the Rhizoma Atractylodis Macrocephalaes; 115～125 parts of Semen Lablab Albums, 55～65 parts in Fructus Jujubae, 28～32 parts in Rhizoma Zingiberis Recens.
3. a kind of Chinese medicine composition of treating infantile malnutrition according to claim 2 is characterized in that this Chinese medicine composition is processed by following bulk drugs: 120 parts of Fructus Polygoni Orientaliss, 60 parts of Fructus Crataegis; 60 parts of Fructus Hordei Germinatus (parched)s, 60 parts of Endothelium Corneum Gigeriae Galli, 60 parts of Massa Medicata Fermentatas; 30 parts of Pericarpium Citri Reticulataes, 30 parts of Semen Arecaes, 60 parts of the Rhizoma Atractylodis Macrocephalaes; 120 parts of Semen Lablab Albums, 60 parts in Fructus Jujubae, 30 parts in Rhizoma Zingiberis Recens.
4. a kind of Chinese medicine composition of treating infantile malnutrition according to claim 2 is characterized in that this Chinese medicine composition is processed by following bulk drugs: 125 parts of Fructus Polygoni Orientaliss, 65 parts of Fructus Crataegis; 65 parts of Fructus Hordei Germinatus (parched)s, 65 parts of Endothelium Corneum Gigeriae Galli, 65 parts of Massa Medicata Fermentatas; 32 parts of Pericarpium Citri Reticulataes, 32 parts of Semen Arecaes, 65 parts of the Rhizoma Atractylodis Macrocephalaes; 125 parts of Semen Lablab Albums, 65 parts in Fructus Jujubae, 32 parts in Rhizoma Zingiberis Recens.
5. a kind of Chinese medicine composition of treating infantile malnutrition according to claim 2 is characterized in that this Chinese medicine composition is processed by following bulk drugs: 115 parts of Fructus Polygoni Orientaliss, 55 parts of Fructus Crataegis; 55 parts of Fructus Hordei Germinatus (parched)s, 55 parts of Endothelium Corneum Gigeriae Galli, 55 parts of Massa Medicata Fermentatas; 28 parts of Pericarpium Citri Reticulataes, 28 parts of Semen Arecaes, 55 parts of the Rhizoma Atractylodis Macrocephalaes; 115 parts of Semen Lablab Albums, 55 parts in Fructus Jujubae, 28 parts in Rhizoma Zingiberis Recens.
6. according to the described a kind of Chinese medicine composition of treating infantile malnutrition of arbitrary claim in the claim 1 to 5, it is characterized in that the dosage form of said Chinese medicine composition is tablet, capsule, oral solutions, granule, powder, pill or syrup.
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| CN103191363A (en) * | 2013-04-12 | 2013-07-10 | 杨邱月 | Traditional Chinese medicine composition for treating infantile malnutrition and preparation method of traditional Chinese medicine composition |
| CN104258261A (en) * | 2014-10-19 | 2015-01-07 | 张利民 | Traditional Chinese medicine agentia for treating accumulation and stagnation in children |
| CN104815266A (en) * | 2015-05-21 | 2015-08-05 | 李玉芬 | Traditional Chinese medicine formula for treating infantile indigestion with food retention |
| CN109953337A (en) * | 2019-04-22 | 2019-07-02 | 山东古之滕商务发展有限公司 | A kind of food and preparation method thereof that can promote children's gastro-intestinal digestion absorption function |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103191363A (en) * | 2013-04-12 | 2013-07-10 | 杨邱月 | Traditional Chinese medicine composition for treating infantile malnutrition and preparation method of traditional Chinese medicine composition |
| CN103191363B (en) * | 2013-04-12 | 2014-03-12 | 杨邱月 | Traditional Chinese medicine composition for treating infantile malnutrition and preparation method of traditional Chinese medicine composition |
| CN104258261A (en) * | 2014-10-19 | 2015-01-07 | 张利民 | Traditional Chinese medicine agentia for treating accumulation and stagnation in children |
| CN104815266A (en) * | 2015-05-21 | 2015-08-05 | 李玉芬 | Traditional Chinese medicine formula for treating infantile indigestion with food retention |
| CN109953337A (en) * | 2019-04-22 | 2019-07-02 | 山东古之滕商务发展有限公司 | A kind of food and preparation method thereof that can promote children's gastro-intestinal digestion absorption function |
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Application publication date: 20120328 |