CN107875255A - A kind of composition for relaxing bowel, losing weight - Google Patents
A kind of composition for relaxing bowel, losing weight Download PDFInfo
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- CN107875255A CN107875255A CN201711165828.2A CN201711165828A CN107875255A CN 107875255 A CN107875255 A CN 107875255A CN 201711165828 A CN201711165828 A CN 201711165828A CN 107875255 A CN107875255 A CN 107875255A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/68—Plantaginaceae (Plantain Family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/482—Cassia, e.g. golden shower tree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
Abstract
The invention discloses a kind of composition for relaxing bowel, losing weight, composition includes circle luxuriant isapgol husk, fructus cannabis and/or konjaku flour, sesame and/or cassia seed, dessert almond and the optional Radix Astragali.The composition of the present invention, using a variety of integration of drinking and medicinal herbs food materials safe to the human body or the medicinal material available for health products, the basic theories based on traditional Chinese medicine carries out scientific compatibility and obtained.Its taste delicate fragrance, it is nutritious, there is the effect of relaxing bowel, losing weight, have significant curative effect to chronic constipation, obesity, suitable various people take.
Description
Technical field
The present invention relates to a kind of functional food or health products, more particularly to it is a kind of have relax bowel, weight losing function
Functional food or health products.
Background technology
As people's life-time dilatation and the change of eating habit and the influence of social pressures factor, the constipation incidence of disease have increasing
High trend, according to incompletely statistics, illness rate of the constipation in crowd are up to 27%, and constipation is often shown as:Awareness of defecation is few, bowel frequency
It is few;Defecation is difficult, laborious;Defecation is not smooth;Dry and hard excrement, it is hard just, defecation is not felt only;Constipation is with stomachache or abdominal discomfort;Mesh
It is preceding treatment constipation health products it is a lot, but with the presence of it is different degrees of the drawbacks of:Damage is brought to body as strongly drained, such as
The Anthraquinones such as rheum officinale cause intestinal mucosa damage, colonoscopy to find large intestine blackening.Drug side-effect easily causes greatly hepatic injury,
Easily form constipation after dependence is discontinued aggravates, and price is higher etc..
Simultaneously as overnutrition, lack motion, life is irregular etc., and the incidence of disease of obesity is increasing year by year, into
A kind of epidemic disease to be increased sharply for global range.As the fast development of economy and the rapid of living standards of the people carry
Height, the overweight and fat illness rate in China rise at double, and particularly population of adolescent rises more obvious.It is estimated that China's mesh
Before possess super severe one at least 200,000,000 to 300,000,000, overweight people at least 3,000 ten thousand to 4,000 ten thousand.
Fat closely related with health, the probability that a variety of diseases occur for overweight people is far above weight standard person.These diseases
Including but not limited to hypertension, dyslipidemia, coronary heart disease, cerebral arterial thrombosis, diabetes, breast cancer, the carcinoma of the rectum, prostate
Cancer, OSAS, gout, edema of lower extremity, waist-leg arthralgia and osteoporosis etc., have a strong impact on life matter
Amount.The worry and threat that obesity is brought more and more are taken seriously.Fat-reducing heat also turns into a Sina have swept the globe
Tide.Medicine or health products fat-reducing are mainly lost weight by reducing human body to realizations such as fatty absorption, increase metabolism, relative ease,
But also have serious interference to the normal function of human body, certain side effect be present, the treatment to obesity still lacks
Safe and effective means.
The content of the invention
It is an object of the invention to overcome the deficiencies of the prior art and provide a kind of safe and reliable, profit having no side effect substantially
Intestines defaecation, the composition of fat-reducing.
The technical solution used in the present invention is:
A kind of composition for relaxing bowel, losing weight, the mass fraction of its action raw material are:
Luxuriant 30~70 parts of the isapgol husk of circle, fructus cannabis and/or 10~40 parts of konjaku flour, sesame and/or cassia seed 10~30
Part, 10~30 parts of dessert almond;Or
Luxuriant 30~60 parts of the isapgol husk of circle, fructus cannabis and/or 10~40 parts of konjaku flour, sesame and/or cassia seed 10~30
Part, 10~30 parts of dessert almond, 10~40 parts of the Radix Astragali.
As the further improvement of above-mentioned composition, consisting of:Luxuriant 45~70 parts of the isapgol husk of circle, fructus cannabis and/or
10~15 parts of 10~15 parts of konjaku flour, sesame and/or cassia seed, 10~15 parts of dessert almond;Or
Luxuriant 40~60 parts of the isapgol husk of circle, fructus cannabis and/or 10~15 parts of konjaku flour, sesame and/or cassia seed 10~15
Part, 10~15 parts of dessert almond, 10~15 parts of the Radix Astragali.
As the further improvement of above-mentioned composition, composition also includes acceptable auxiliary material.
As the further improvement of above-mentioned composition, composition is oral agents.
As the further improvement of above-mentioned composition, oral agents are selected from solid beverage, solid powder, granule, tablet, glue
Wafer, oral latex emulsion.
A kind of preparation method for the composition for relaxing bowel, losing weight, comprises the following steps:By the proportioning of composition, weigh
It raw material, dry, pulverize, be uniformly mixed so as to obtain composition, wherein, the composition of composition is as described above.
As the further improvement of the above method, re-dry after raw material is cured, crush.
As the further improvement of the above method, the method for curing is to cook or fry.
The beneficial effects of the invention are as follows:
The composition of the present invention, using a variety of integration of drinking and medicinal herbs food materials safe to the human body or the medicinal material available for health products,
Basic theories based on traditional Chinese medicine carries out scientific compatibility and obtained.Its taste delicate fragrance, it is nutritious, have and relax bowel, lose weight
Effect, there is significant curative effect to chronic constipation, obesity, and suitable various people take.
Embodiment
A kind of composition for relaxing bowel, losing weight, the mass fraction of its action raw material are:
Luxuriant 30~70 parts of the isapgol husk of circle, fructus cannabis and/or 10~40 parts of konjaku flour, sesame and/or cassia seed 10~30
Part, 10~30 parts of dessert almond;Or
Luxuriant 30~60 parts of the isapgol husk of circle, fructus cannabis and/or 10~40 parts of konjaku flour, sesame and/or cassia seed 10~30
Part, 10~30 parts of dessert almond, 10~40 parts of the Radix Astragali.
As the further improvement of above-mentioned composition, consisting of:Luxuriant 45~70 parts of the isapgol husk of circle, fructus cannabis and/or
10~15 parts of 10~15 parts of konjaku flour, sesame and/or cassia seed, 10~15 parts of dessert almond;Or
Luxuriant 40~60 parts of the isapgol husk of circle, fructus cannabis and/or 10~15 parts of konjaku flour, sesame and/or cassia seed 10~15
Part, 10~15 parts of dessert almond, 10~15 parts of the Radix Astragali.
Fructus cannabis and konjaku flour both can be used alone, and can also be used in mixed way.Sesame and cassia seed both can individually make
With can also be used in mixed way.For the sake of convenient preparation, preferably it is used alone.
Circle luxuriant isapgol husk, fructus cannabis and/or konjaku flour, sesame and/or cassia seed mainly act on large intestine, have ease constipation
The effect of defaecation;The dessert almond acted on according to the theoretical addition of traditional Chinese medical science the lung and the large intestine being interior-exteriorly related with facilitaing lung sending down abnormally ascending, reaches enhancing
The effect of defecation;Again by adding the Radix Astragali, further tonifying Qi, promote defecation.The effect of composition can further be lifted.
As the further improvement of above-mentioned composition, composition also includes acceptable auxiliary material.These auxiliary materials are included but not
It is limited to flavouring, thickener, antitack agent etc..
As the further improvement of above-mentioned composition, composition is oral agents.
As the further improvement of above-mentioned composition, oral agents are selected from solid beverage, solid powder, granule, tablet, glue
Wafer, oral latex emulsion.Particularly, oral agents are solid beverage, add water to reconstitute into beverage during use, oral afterwards.
A kind of preparation method for the composition for relaxing bowel, losing weight, comprises the following steps:By the proportioning of composition, weigh
It raw material, dry, pulverize, be uniformly mixed so as to obtain composition, wherein, the composition of composition is as described above.
As the further improvement of above-mentioned preparation method, re-dry after raw material is cured, crush.For what need not be cured
Raw material, it can directly be mixed and made into powder;Or powder is made and remixes afterwards uniformly.
As the further improvement of above-mentioned preparation method, the method for curing is to cook or fry.
With reference to embodiment, technical scheme is further illustrated.
In following examples, unless otherwise instructed, composition is to cook rear re-dry, is crushed, and is sterilized after well mixed
Pack, obtains product;Described number unless otherwise instructed, refers both to mass parts.
Embodiment 1:
A kind of composition for relaxing bowel, losing weight, consisting of:Luxuriant 50 parts of the isapgol husk of circle, 15 parts of fructus cannabis, sesame 15
Part, 10 parts of dessert almond.
Embodiment 2:
A kind of composition for relaxing bowel, losing weight, consisting of:Luxuriant 70 parts of the isapgol husk of circle, 10 parts of fructus cannabis, sesame 30
Part, 10 parts of cassia seed, 20 parts of dessert almond.
Embodiment 3:
A kind of composition for relaxing bowel, losing weight, consisting of:Luxuriant 30 parts of the isapgol husk of circle, 20 parts of fructus cannabis, konjaku flour
20 parts, 5 parts of sesame, 15 parts of cassia seed, 20 parts of dessert almond.
Embodiment 4:
A kind of composition for relaxing bowel, losing weight, consisting of:Luxuriant 45 parts of the isapgol husk of circle, 10 parts of konjaku flour, sesame 15
Part, 10 parts of dessert almond.
Embodiment 5:
A kind of composition for relaxing bowel, losing weight, consisting of:Luxuriant 60 parts of the isapgol husk of circle, 13 parts of fructus cannabis, sesame 10
Part, 15 parts of dessert almond.
Embodiment 6:
A kind of composition for relaxing bowel, losing weight, consisting of:Luxuriant 30 parts of the isapgol husk of circle, 20 parts of fructus cannabis, konjaku flour
10 parts, 20 parts of sesame, 20 parts of dessert almond, 20 parts of the Radix Astragali.
Embodiment 7:
A kind of composition for relaxing bowel, losing weight, consisting of:Luxuriant 60 parts of the isapgol husk of circle, 15 parts of fructus cannabis, konjaku flour
25 parts, 5 parts of sesame, 10 parts of cassia seed, 30 parts of dessert almond, 40 parts of the Radix Astragali.
Embodiment 8:
A kind of composition for relaxing bowel, losing weight, consisting of:Luxuriant 40 parts of the isapgol husk of circle, 15 parts of konjaku flour, sesame 10
Part, 10 parts of dessert almond, 15 parts of the Radix Astragali.
Embodiment 9:
A kind of composition for relaxing bowel, losing weight, consisting of:Luxuriant 50 parts of the isapgol husk of circle, 10 parts of fructus cannabis, cassia seed
15 parts, 15 parts of dessert almond, 10 parts of the Radix Astragali.
Embodiment 10:
A kind of composition for relaxing bowel, losing weight, consisting of:Luxuriant 45 parts of the isapgol husk of circle, 15 parts of fructus cannabis, sesame 12
Part, 12 parts of dessert almond, 13 parts of the Radix Astragali.
Embodiment 11:
A kind of composition for relaxing bowel, losing weight, consisting of:Luxuriant 50 parts of the isapgol husk of circle, 10 parts of fructus cannabis, sesame 10
Part, 10 parts of dessert almond, 10 parts of the Radix Astragali.
Embodiment 12:
A kind of composition for relaxing bowel, losing weight, consisting of:Luxuriant 50 parts of the isapgol husk of circle, 10 parts of fructus cannabis, sesame 10
Part, 10 parts of dessert almond.
With reference to experiment, technical scheme is further illustrated.
The present composition is to chronic constipation and fat influence
After patient's informed consent is obtained, using the present invention relax bowel, Weight reducing compound to 50 with it is chronic just
Secret adult is observed.
Method:That respectively takes embodiment 1 sooner or later daily relaxes bowel Weight reducing compound once, and 9 grams every time (containing the luxuriant Chinese herbaceous peony of circle
Sub- 5 grams of shell, 1.5 grams of fructus cannabis, 1.5 grams of sesame, 1 gram of dessert almond, are reconstituted to 400~500mL using boiling water, are taken after cooling),
It even served 30 days.
50 constipation patients times of defecation before this product is taken is less than 3 times weekly, meets the diagnostic criteria of constipation.After taking this product
1st~10 day stool is 1 time a day or every two days 1 time;Observation was defecated daily 1~2 time, 3 to 30 days 47 (94%)
(6%) defecate every two days 1 time, the state of an illness is alleviated significantly, obtains preferable clinical efficacy.Take and do not observe and this during this product
The adverse reaction that condition closes.
Specific case:
Unless otherwise instructed, used in following case relax bowel, diet food be embodiment 1 composition, use
Method is:Take in the morning and evening daily, 9 grams every time (containing luxuriant 5 grams of the isapgol husk of circle, 1.5 grams of fructus cannabis, 1.5 grams of sesame, sweet tea
1 gram of almond, is reconstituted to 400~500mL using boiling water, is taken after cooling).
Case 1:Female middle-aged, prolonged constipation, defecate 4-5 days once, demand long-term use cathartic.Take the profit of the present invention
Start within the 8th day after intestines defaecation, diet food, stool once begins stool on the 16th day once a day, unobstructed, spirit is happy in 2 days.
Case 2:Elderly men, suffer from diabetes, hypertension, osteoporosis with constipation 6 years, dry and hard excrement, 3~4 days one
It is secondary, demand long-term use cathartic.Relaxing bowel, starting for the 5th day after diet food for the present invention is taken, stool shape is normal, logical
Freely, daily 1~2 time.
Case 3:Young women, height 158cm, body weight 70kg, dry and hard excrement, 2~3 days once, and demand long-term use is rushed down
Medicine.Take the present invention relax bowel, the slimming health product (composition of embodiment 11, containing 5 grams of the luxuriant isapgol husk of circle, fructus cannabis 1
Gram, 1 gram of sesame, 1 gram of dessert almond, 1 gram of the Radix Astragali, reconstituted to 400~500mL using boiling water, taken after cooling).Start within 4th day,
Defecate shape it is normally unobstructed, daily 1~2 time, take the present invention relax bowel, the 50th day after slimming health product, body weight 65kg.
Influence of the present composition to mouse defecation
Experimental program:
Kunming mouse, male female half and half, body weight (20 ± 2g), take 40 progress constipation modelings, modeling success at random by 50
Take 30 at random afterwards, be divided into model group, administration without Radix Astragali group, administration group containing the Radix Astragali, every group 10, the 10 of non-modeling is only used as
Blank control group.
Modeling medicine is compound diphenoxylate, dosage 10mg/kg;
What is given is without Milkvetch root composition:Luxuriant 10 grams of the isapgol husk of circle, 3 grams of fructus cannabis, 3 grams of sesame, 2 grams of dessert almond;
It is containing Milkvetch root composition:Luxuriant 10 grams of the isapgol husk of circle, 2 grams of fructus cannabis, 2 grams of sesame, 2 grams of dessert almond, 2 grams of the Radix Astragali
(composition of embodiment 11).
Processing method:The dosage for giving every mouse is 1.8g/kg, adds water to be made into 2ml/ gavage, blank control group and
Gavage gives isometric physiological saline to model group respectively.
Record defecation time first after administration, defecation grain number and excrement shape in 6h.Experimental result is as shown in table 1.
The influence (n=10) of table 1, composition to mice with constipation model defecation situation
Note:Compared with model group, *:P<0.05.Compared with without Radix Astragali group,#:P<0.05.
Compared with group containing the Radix Astragali, *#:P<0.01.
Influence of the present composition to mice with constipation small intestine promotion rate
Experimental program:
Kunming mouse, male female half and half, body weight (20 ± 2g), are randomly divided into blank control group, administration is free of the Radix Astragali by 30
Group, administration group containing the Radix Astragali, every group 10.
Modeling medicine is compound diphenoxylate, dosage 10mg/kg;
What is given is without Milkvetch root composition:Luxuriant 10 grams of the isapgol husk of circle, 3 grams of fructus cannabis, 3 grams of sesame, 2 grams of dessert almond;
It is containing Milkvetch root composition:Luxuriant 10 grams of the isapgol husk of circle, 2 grams of fructus cannabis, 2 grams of sesame, 2 grams of dessert almond, 2 grams of the Radix Astragali
(composition of embodiment 11).
Processing method:The dosage for giving every mouse is 1.8g/kg, adds water to be made into 2ml/ gavage, blank control group is given
Give isometric physiological saline gavage.Influence to mice with constipation small intestine promotion rate, prepared Chinese ink is given by gavage, at cervical dislocation
Dead animal, abdomen separation mesenterium is opened, clip intestinal tube, ink progradation is calculated by the prepared Chinese ink propulsion trial of classics.Result of the test is such as
Shown in table 2.
The influence (n=10) of table 2, composition to mouse small intestine promotion rate
Note:Compared with blank control group, *:P<0.05.Compared with without Radix Astragali group,#:P<0.05.
Compared with group containing the Radix Astragali, *#:P<0.01.
The present composition is counted compound diphenoxylate Constipation Model mouse argol, loose stool points, not defecation animal
Research shows that there were significant differences for model group contrast each group argol points;This product group containing the Radix Astragali and difference without Radix Astragali group have system
Meter learns meaning.There is more preferable improvement to constipation after the addition Radix Astragali.
In terms of mouse small intestine promotion rate, this product is compared with blank control group, the equal significance of difference.And this product is containing Huang
Stilbene group is compared with without Radix Astragali group, and group containing the Radix Astragali is significantly improved to mouse small intestine promotion rate, and difference is statistically significant.
Claims (8)
1. a kind of composition for relaxing bowel, losing weight, the mass fraction of its action raw material are:
Circle luxuriant 10~40 parts of 30~70 parts of isapgol husk, fructus cannabis and/or konjaku flour, sesame and/or 10~30 parts of cassia seed, sweet tea
10~30 parts of almond;Or
Circle luxuriant 10~40 parts of 30~60 parts of isapgol husk, fructus cannabis and/or konjaku flour, sesame and/or 10~30 parts of cassia seed, sweet tea
10~30 parts of almond, 10~40 parts of the Radix Astragali.
2. composition according to claim 1, it is characterised in that:The mass fraction of its raw material is:
Circle luxuriant 10~15 parts of 45~70 parts of isapgol husk, fructus cannabis and/or konjaku flour, sesame and/or 10~15 parts of cassia seed, sweet tea
10~15 parts of almond;Or
Circle luxuriant 10~15 parts of 40~60 parts of isapgol husk, fructus cannabis and/or konjaku flour, sesame and/or 10~15 parts of cassia seed, sweet tea
10~15 parts of almond, 10~15 parts of the Radix Astragali.
3. composition according to claim 1, it is characterised in that:Also include acceptable auxiliary material.
4. according to the composition described in any one of claims 1 to 3, it is characterised in that:Composition is oral agents.
5. composition according to claim 4, it is characterised in that:Oral agents are selected from solid beverage, solid powder, particle
Agent, tablet, capsule, oral latex emulsion.
6. a kind of preparation method for the composition for relaxing bowel, losing weight, comprises the following steps:By the proportioning of composition, original is weighed
Material, dry, pulverize, be uniformly mixed so as to obtain composition, wherein, the composition of composition is as described according to any one of claims 1 to 3.
7. preparation method according to claim 6, it is characterised in that:Re-dry after raw material is cured, crush.
8. preparation method according to claim 6, it is characterised in that:The method of curing is to cook or fry.
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Cited By (6)
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CN109619487A (en) * | 2018-10-26 | 2019-04-16 | 华中农业大学 | Composition and preparation method thereof with function of relaxing bowel |
CN110214948A (en) * | 2019-07-07 | 2019-09-10 | 广州正广生物科技有限公司 | A kind of composition and preparation method thereof with function of relaxing bowel |
CN110916184A (en) * | 2019-12-09 | 2020-03-27 | 雷允上药业集团有限公司 | Health product with function of relaxing bowels and preparation method thereof |
CN111298021A (en) * | 2020-04-07 | 2020-06-19 | 湖南中医药大学第一附属医院((中医临床研究所)) | Traditional Chinese medicine composition for treating functional constipation |
CN113439807A (en) * | 2020-03-25 | 2021-09-28 | 广州万康保健品有限公司 | Beverage for losing weight and preparation method thereof |
CN116138454A (en) * | 2021-11-19 | 2023-05-23 | 宁夏枸杞创新中心(有限公司) | Fructus lycii medicinal and edible dual-purpose composition with constipation relieving effect and preparation method and application thereof |
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