CN105326779A - Moisturizing, brightening and whitening hair gel and preparation method thereof - Google Patents
Moisturizing, brightening and whitening hair gel and preparation method thereof Download PDFInfo
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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Abstract
The invention belongs to the technical field of cosmetics, and particularly relates to a moisturizing, brightening and whitening hair gel and a preparation method thereof. The hair gel disclosed by the invention contains tremella extract, glycyrrhiza glabra root extract and bi-PEG-18 glycol methyl ether dimethylsilane. The whitening ingredients of the hair gel are obtained through sieving, the whitening ingredients are added to the substrate of the cosmetic, and the Melanin value and Melanin content of the skin can be well reduced, so that the hair gel disclosed by the invention plays a good role in inhibiting melanin, namely the hair gel has an excellent whitening effect; moreover, the hair gel disclosed by the invention is high in stability.
Description
Technical field
The invention belongs to cosmetic technical field, be specifically related to bright whitening gel of a kind of Shu Run jade-like stone and preparation method thereof.
Background technology
Skin-whitening and nursing are the themes of cosmetics, and the cosmetics with skin-whitening and skin-care function are one of best-selling cosmetics.Modern scientific research proves, skin aging is a very complicated process, is subject to the impact of many factors, and wherein melanic generation and free radical cause the degeneration of elastic fibers of skin to be two large principal elements.Melanic forming process is: the tyrosine (tyrosine) in human body skin melanocyte is oxidized generation DOPA (dopa) and DOPA quinone (dopaquinone) under the catalytic action of tryrosinase, dopachrome (dopachrome), 5 is generated through resetting laggard oxidation step, 6-dihydroxy indole (5,6-dihydroxyindole), istain (indole-5,6-quinone), final synthesis of melanin (melanin).The principal element affecting melanic formation has: the quantity of melanocyte, the activity of tryrosinase, the content of oxygen-derived free radicals and the content of tyrosine.Wherein, tyrosine is the aminoacid of needed by human, and its content is controlled by human body self.So, melanic formation be controlled, can only by controlling the content of the quantity of melanocyte, the activity of tryrosinase and oxygen-derived free radicals.So from the angle of safety, the approach of skin-whitening and skin nursing mainly contains the following aspects: one is by suppressing dermal melanin cell proliferation, reduces the quantity that melanocyte generates; Two is the catalytic activitys of key enzyme-tryrosinase by suppressing dermal melanin to generate, thus reduces melanic generating rate and reach whitening object; Three is by sun-proof, prevents sunlight middle-ultraviolet lamp to the injury (tanned and sunburn) of skin, slows down skin aging; Four is the oxygen-derived free radicals by using in antioxidant removal skin, slows down melanin and generates and slow down skin aging.At present, all there is larger defect in the management of China's skin-lightening cosmetic and technology, the phenomenon of adding in violation of rules and regulations is very serious, what have even bleaches using contrabands such as aminomercuric chlorides as peroxide such as whitening agent or interpolation hydrogen peroxide, cause many beauty treatment accidents for many years, even disfeature, cause very large injury to consumer, caused the great attention of country and consumer.In recent years, the whitening agent used in cosmetics mainly contains the compounds such as hydroquinone (hydroquinone), L-AA (vitamin C), kojic acid, superoxide dismutase (SOD) and arbutin.But these whitening agents also exist many defects, the zest as hydroquinone is very large, and vitamin C and SOD are very unstable, and kojic acid also has certain zest and property easy to change, the single and poor effect of arbutin effect etc.So exploitation has good safety, stability, inhibition is obvious, and the natural whiting agent that cost performance is good, has become one of main direction of studying of current medicine and cosmetic industry, had extraordinary development prospect.Natural materials is applied to cosmetics can reach skin treating and skin protection double effects, and has diverse in function, the characteristic such as widely applicable, safe, thus day by day comes into one's own.Patent of invention CN102225039A discloses a kind of whitening Chinese medicament compositions containing Radix Glycyrrhizae, Cortex Moutan, Fructus Atriplicis Sibiricae, Rhizoma Polygonati, Herba Leonuri, and this Chinese medicine composition adopts decocting method to carry out extraction preparation.Patent of invention CN101612105 disclose a kind of by the Pseudobulbus Bletillae (Rhizoma Bletillae), hold back in vain, Cortex Mori, Poria, Fructus Atriplicis Sibiricae, the Rhizoma Atractylodis Macrocephalae, Fructus Amomi Rotundus, the Radix Paeoniae Alba, Herba Pyrolae and Radix Angelicae Sinensis the whitening and skin-protecting Chinese medicine composition that forms of extract and preparation method thereof, said composition adopts the method preparation of soak extraction and anion exchange resin separation and concentration.Patent of invention CN101732223A disclose a kind of by Aloe, Faeces Passeris, lead a cow in vain, pure Chinese medicine active white skin care solution that Poria, Semen Ginkgo core, the Pseudobulbus Bletillae (Rhizoma Bletillae), the Radix Angelicae Dahuricae, the Rhizoma Atractylodis Macrocephalae, Nidus collocaliae, Semen Coicis, Radix Gentianae, Radix Angelicae Sinensis, Semen Ginkgo form, this Chinese medicine composition adopts decocting method to carry out extractions to prepare.Patent of invention CN101804185A discloses a kind of freckle removal traditional Chinese medicinal composition containing Radix Bupleuri, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Fructus Corni, the Rhizoma Atractylodis Macrocephalae, Poria, Rhizoma Chuanxiong, Semen Persicae, Bombyx Batryticatus, Roast Rhizoma Zingiberis Recens, Herba Menthae and Radix Glycyrrhizae Preparata, and this Chinese medicine composition have employed and adopts carbon dioxide supercritical fluid extraction technology to extract.Above-mentioned Chinese medicine composition adds in cosmetic base, although can solve the problem of skin-lightening cosmetic zest, stability, these cosmetic appearance are poor, whitening effect needs the longer time, therefore, the better skin-lightening cosmetic of research and development, significant further.
Summary of the invention
For these reasons, applicant, through years of researches, obtains a kind of new gel, and containing whitening composition in this gel, whitening composition comprises: Tremella extract, Glycyrrhiza glabra L. root extract, two-PEG-18 methyl ether dimethylsilane.Whitening composition of the present invention is obtained by screening, above-mentioned whitening composition is added in cosmetic base, Mai Laning value and the Mai Laning content of skin can well be reduced, absolutely prove that gel of the present invention has the effect of good check melanin, namely there is good whitening function; In addition, gel of the present invention has good stability.
The present invention is achieved through the following technical solutions.
A kind of gel, containing Tremella extract, Glycyrrhiza glabra L. root extract, two-PEG-18 methyl ether dimethylsilane.
Wherein Tremella extract 0.04-0.06 weight portion, Glycyrrhiza glabra L. root extract 0.04-0.06 weight portion, two-PEG-18 methyl ether dimethylsilane 0.4-0.6 weight portion.
The application of compositions in skin-lightening cosmetic of described Tremella extract, Glycyrrhiza glabra L. root extract and two-PEG-18 methyl ether dimethylsilane.
The raw material wherein preparing gel comprises: betanin, glycerol, 1, 2-pentanediol, 1, 3-butanediol, 1, 2-propylene glycol, 1, ammediol, 1, 2-hexanediol, carbomer, sodium hydroxide, caprylyl glycol, beta glucan, hydrolyzed vegetable protein, adenosine triphosphate, sodium chondroitin sulfate, resveratrol, Flos Chrysanthemi extract, maltodextrin, denatonium benzoate, soluble protein polysaccharide, prunus mume (sieb.) sieb.et zucc. berry extract, Cynara scolymus L (Cyhara cardunculus.) leaf extract, Citrus junos fruit extract, artemia extract, platinum powder, Tremella extract, Glycyrrhiza glabra L. root extract, two-PEG-18 methyl ether dimethylsilane.
The raw material wherein preparing gel comprises: betanin 4-6 weight portion, glycerol 2-4 weight portion, 1,2-pentanediol 2-4 weight portion, 1,3 butylene glycol 2-4 weight portion, 1,2-PD 2-4 weight portion, 1,3-PD 2-4 weight portion, 1,2-hexanediol 1-2 weight portion, carbomer 0.2-0.4 weight portion, sodium hydroxide 0.1-0.3 weight portion, caprylyl glycol 0.1-0.2 weight portion, beta glucan 0.001-0.003 weight portion, hydrolyzed vegetable protein 0.0002-0.0003 weight portion, adenosine triphosphate 0.0002-0.0003 weight portion, sodium chondroitin sulfate 0.0002-0.0003 weight portion, resveratrol 0.0001-0.0003 weight portion, Flos Chrysanthemi extract 0.0001 weight portion, maltodextrin 0.0001 weight portion, denatonium benzoate 0.00002 weight portion, soluble protein polysaccharide 0.000005 weight portion, prunus mume (sieb.) sieb.et zucc. berry extract 0.000004 weight portion, Cynara scolymus L (Cyhara cardunculus.) leaf extract 0.0000004 weight portion, Citrus junos fruit extract 0.0000003 weight portion, artemia extract 0.0000002 weight portion, platinum powder 0.0000002 weight portion, Tremella extract 0.04-0.06 weight portion, Glycyrrhiza glabra L. root extract 0.04-0.06 weight portion, two-PEG-18 methyl ether dimethylsilane 0.4-0.6 weight portion.
The preparation method of described gel is:
(1) water intaking, betanin, glycerol, 1,3 butylene glycol, 1,3-PD, 1,2-propylene glycol, 1,2-hexanediol, two-PEG-18 methyl ether dimethylsilane, caprylyl glycol, carbomer, add aqueous phase pot, after being heated to 80-85 DEG C, stir, in suction vacuum emulsifying machine;
(2) start is uniformly mixed, and 30 minutes, 1000rpm/ divided, and stops stirring, is cooled to 40 DEG C; Add water, glycerol, 1,2-hexanediol, 1,2-pentanediol, beta glucan, Glycyrrhiza glabra L. root extract, sodium hydroxide, Tremella extract, 1,3-butanediol, hydrolyzed vegetable protein, adenosine triphosphate, sodium chondroitin sulfate, artemia extract, platinum powder, Citrus junos fruit extract, soluble protein polysaccharide, Cynara scolymus L (Cyhara cardunculus.) leaf extract, prunus mume (sieb.) sieb.et zucc. berry extract, resveratrol, maltodextrin, Flos Chrysanthemi extract, denatonium benzoate, continue to stir, be cooled to room temperature; Fill, to obtain final product.
Following is purchase producer and the lot number of part material of the present invention:
Detailed description of the invention
Below in conjunction with example, the present invention is elaborated.Following examples do not limit protection scope of the present invention.
Following test, be on the basis of repeatedly creative test, for the claimed content of the present invention, the concluding of carrying out is tested.
One, screening test
Test 1 group: Tremella extract 0.05g, Glycyrrhiza glabra L. root extract 0.05g.
Test 2 groups: Tremella extract 0.1g, Glycyrrhiza glabra L. root extract 0.1g.
Test 3 groups: Tremella extract 0.5g, Glycyrrhiza glabra L. root extract 0.5g.
Test 4 groups: Tremella extract 0.05g, Glycyrrhiza glabra L. root extract 0.05g, two-PEG-18 methyl ether dimethylsilane 0.5g.
Test 5 groups: Tremella extract 0.05g, Glycyrrhiza glabra L. root extract 0.05g, two-PEG-18 methyl ether dimethylsilane 1g.。
Test specimen is prepared: get 1,3 butylene glycol 1g, add water 1g, and mixing completely.Get test 1 group of raw material, add in above-mentioned solvent, mixing is completely, for subsequent use; Test 2 groups, test 3 groups, compound method is the same.
Test method: get human body skin threedimensional model test box (MEL-300B).According to this test operation flow process, threedimensional model is moved in 6 porocyte culture plates, be placed in 37 DEG C, 5%CO by long term maintenance culture medium (EPI-100LLMM)
2lower calorstat preculture, after 1 hour, adds different tests group, adds preparing test specimen 100 μ L to horny layer side respectively, the blank group of 1,3 butylene glycol aqueous solution adding equivalent.Basal layer side uses long term maintenance culture medium to continue to cultivate.The interval of 2 days or 3 days exchanges the cultivation that culture medium and tested material are carried out 16 days altogether.After cultivation, after washing skin histology by PBS (-) buffering, MX18 (manufacture of Courage+Khazaka company) is utilized to test the Mai Laning value of different group.
Result of the test: in table 1.
The Mai Laning value of table 1 different tests group
| Test group | Mai Laning value (a.u.) |
| Blank group | 501.2±1.1 |
| Test 1 group | 403.2±0.9** |
| Test 2 groups | 394.1±1.2** |
| Test 3 groups | 390.2±0.9** |
| Test 4 groups | 327.4±0.5*** |
| Test 5 groups | 325.1±0.9*** |
Note: compare * * P<0.01 with blank group, * * * P<0.001.
Conclusion (of pressure testing): known Mai Laning value is lower, illustrates that the ability of check melanin is stronger, above-mentioned test data shows, after Glycyrrhiza glabra L. root extract and Tremella extract combination, (testing 1 group) can well check melanin, after increasing Tremella extract and licorice root extract weight, do not improve whitening effect, but after adding two-PEG-18 methyl ether dimethylsilane, Mai Laning value reduces greatly (comparing P<0.001 with blank group), continue the amount increasing two-PEG-18 methyl ether dimethylsilane, do not improve the ability of check melanin further, therefore, applicant determines that the compositions of test 4 groups is whitening composition.
Two, demonstration test
Test 1 group: betanin 4g, glycerol 2g, 1, 2-pentanediol 2g, 1, 3-butanediol 2g, 1, 2-propylene glycol 2g, 1, ammediol 2g, 1, 2-hexanediol 1g, carbomer 0.2g, sodium hydroxide 0.1g, caprylyl glycol 0.1g, beta glucan 0.001g, hydrolyzed vegetable protein 0.0002g, adenosine triphosphate 0.0002g, sodium chondroitin sulfate 0.0002g, resveratrol 0.0001g, Flos Chrysanthemi extract 0.0001g, maltodextrin 0.0001g, denatonium benzoate 0.00002g, soluble protein polysaccharide 0.000005g, prunus mume (sieb.) sieb.et zucc. berry extract 0.000004g, Cynara scolymus L (Cyhara cardunculus.) leaf extract 0.0000004g, Citrus junos fruit extract 0.0000003g, artemia extract 0.0000002g, platinum powder 0.0000002g, Tremella extract 0.04g, Glycyrrhiza glabra L. root extract 0.04g, two-PEG-18 methyl ether dimethylsilane 0.4g.
The preparation method of gel is:
(1) fetch water 50g, betanin, glycerol 0.8g, 1,3-butanediol 0.8g, 1, ammediol, 1,2-propylene glycol, 1,2-hexanediol 0.4g, two-PEG-18 methyl ether dimethylsilane, caprylyl glycol, carbomer, add aqueous phase pot, after being heated to 80-85 DEG C, stir, in suction vacuum emulsifying machine;
(2) start is uniformly mixed, and 30 minutes, 1000rpm/ divided, stop stirring, be cooled to 40 DEG C; Add water 11.6g, glycerol 1.2g, 1,2-hexanediol 0.6g, 1,2-pentanediol, beta glucan, Glycyrrhiza glabra L. root extract, sodium hydroxide, Tremella extract, 1,3-butanediol 1.2g, hydrolyzed vegetable protein, adenosine triphosphate, sodium chondroitin sulfate, artemia extract, platinum powder, Citrus junos fruit extract, soluble protein polysaccharide, Cynara scolymus L (Cyhara cardunculus.) leaf extract, prunus mume (sieb.) sieb.et zucc. berry extract, resveratrol, maltodextrin, Flos Chrysanthemi extract, denatonium benzoate, continue to stir, be cooled to room temperature; Fill, to obtain final product.
Test 2 groups: betanin 5g, glycerol 3g, 1, 2-pentanediol 3g, 1, 3-butanediol 3g, 1, 2-propylene glycol 3g, 1, ammediol 3g, 1, 2-hexanediol 1.5g, carbomer 0.3g, sodium hydroxide 0.2g, caprylyl glycol 0.15g, beta glucan 0.002g, hydrolyzed vegetable protein 0.00025g, adenosine triphosphate 0.00025g, sodium chondroitin sulfate 0.00025g, resveratrol 0.0002g, Flos Chrysanthemi extract 0.0001g, maltodextrin 0.0001g, denatonium benzoate 0.00002g, soluble protein polysaccharide 0.000005g, prunus mume (sieb.) sieb.et zucc. berry extract 0.000004g, Cynara scolymus L (Cyhara cardunculus.) leaf extract 0.0000004g, Citrus junos fruit extract 0.0000003g, artemia extract 0.0000002g, platinum powder 0.0000002g, Tremella extract 0.05g, Glycyrrhiza glabra L. root extract 0.05g, two-PEG-18 methyl ether dimethylsilane 0.5g.
The preparation method of gel is:
(1) fetch water 62g, betanin, glycerol 1.2g, 1,3-butanediol 1.2g, 1, ammediol, 1,2-propylene glycol, 1,2-hexanediol 0.6g, two-PEG-18 methyl ether dimethylsilane, caprylyl glycol, carbomer, add aqueous phase pot, after being heated to 80-85 DEG C, stir, in suction vacuum emulsifying machine;
(2) start is uniformly mixed, and 30 minutes, 1000rpm/ divided, and stops stirring, is cooled to 40 DEG C; Add water 15.3g, glycerol 1.8g, 1,2-hexanediol 0.9,1,2-pentanediol, beta glucan, Glycyrrhiza glabra L. root extract, sodium hydroxide, Tremella extract, 1,3-butanediol 1.8g, hydrolyzed vegetable protein, adenosine triphosphate, sodium chondroitin sulfate, artemia extract, platinum powder, Citrus junos fruit extract, soluble protein polysaccharide, Cynara scolymus L (Cyhara cardunculus.) leaf extract, prunus mume (sieb.) sieb.et zucc. berry extract, resveratrol, maltodextrin, Flos Chrysanthemi extract, denatonium benzoate, continue to stir, be cooled to room temperature; Fill, to obtain final product.
Test 3 groups: betanin 6g, glycerol 4g, 1, 2-pentanediol 4g, 1, 3-butanediol 4g, 1, 2-propylene glycol 4g, 1, ammediol 4g, 1, 2-hexanediol 2g, carbomer 0.4g, sodium hydroxide 0.3g, caprylyl glycol 0.2g, beta glucan 0.003g, hydrolyzed vegetable protein 0.0003g, adenosine triphosphate 0.0003g, sodium chondroitin sulfate 0.0003g, resveratrol 0.0003g, Flos Chrysanthemi extract 0.0001g, maltodextrin 0.0001g, denatonium benzoate 0.00002g, soluble protein polysaccharide 0.000005g, prunus mume (sieb.) sieb.et zucc. berry extract 0.000004g, Cynara scolymus L (Cyhara cardunculus.) leaf extract 0.0000004g, Citrus junos fruit extract 0.0000003g, artemia extract 0.0000002g, platinum powder 0.0000002g, Tremella extract 0.06g, Glycyrrhiza glabra L. root extract 0.06g, two-PEG-18 methyl ether dimethylsilane 0.6g.
The preparation method of gel is:
(1) fetch water 77g, betanin, glycerol 1.6g, 1,3-butanediol 1.6g, 1, ammediol, 1,2-propylene glycol, 1,2-hexanediol 0.8g, two-PEG-18 methyl ether dimethylsilane, caprylyl glycol, carbomer, add aqueous phase pot, after being heated to 80-85 DEG C, stir, in suction vacuum emulsifying machine;
(2) start is uniformly mixed, and 30 minutes, 1000rpm/ divided, and stops stirring, is cooled to 40 DEG C; Add water 18.1g, glycerol 2.4g, 1,2-hexanediol 1.2g, 1,2-pentanediol, beta glucan, Glycyrrhiza glabra L. root extract, sodium hydroxide, Tremella extract, 1,3-butanediol 2.4g, hydrolyzed vegetable protein, adenosine triphosphate, sodium chondroitin sulfate, artemia extract, platinum powder, Citrus junos fruit extract, soluble protein polysaccharide, Cynara scolymus L (Cyhara cardunculus.) leaf extract, prunus mume (sieb.) sieb.et zucc. berry extract, resveratrol, maltodextrin, Flos Chrysanthemi extract, denatonium benzoate, continue to stir, be cooled to room temperature; Fill, to obtain final product.
Demonstration test 1: according to test one screening test, measures the Mai Laning value of different group.
Result of the test: in table 2.
The Mai Laning value of the different gel of table 2 compares
| Test group | Mai Laning value (a.u.) |
| Blank group | 483.2±0.8 |
| Test 1 group | 339.2±0.9*** |
| Test 2 groups | 330.1±1.2*** |
| Test 3 groups | 335.4±0.9*** |
Note: compare * * P<0.01 with blank group, * * * P<0.001.
Demonstration test 2: Mai Laning assay
The quantitative approach of Mai Laning is by following procedure operation: get skin after above-mentioned test, with tweezers by after skin peeling, insert the 1.0%SDS solution of 450 μ L (containing 10mMTris-HCl, 0.05mMEDTA, pH6.8) after implementing ultrasound fragmentation in, add the pronase e solution 20 μ L of 5mg/mL, heat under 45 DEG C of conditions 12 hours.Adding the 500mMNa of 50 μ L
2cO
3with the 30%H of 10 μ L
2o
2heat under being placed on 80 DEG C of conditions 30 minutes.After cooling, add the chloroform of 100 μ L: methanol (2:1) mixed liquor is stirred, after centrifugalize in 10 minutes, get the measurement that its supernatant 100 μ L spectrogrph carries out when wavelength is 405nm.Utilize synthesis Mai Laning (SIGMA) to carry out same measurement and production standard curve as standard sample, establishing criteria curve carries out quantitatively the Mai Laning contained by skin histology simultaneously.
Result of the test: in table 3.
Table 3 Mai Laning content quantitative result
Note: compare * * P<0.01 with blank group.
Conclusion (of pressure testing): above-mentioned test shows, gel of the present invention has the effect of good check melanin.
Three, stability test
Test 1 group: betanin 5g, glycerol 3g, 1, 2-pentanediol 3g, 1, 3-butanediol 3g, 1, 2-propylene glycol 3g, 1, ammediol 3g, 1, 2-hexanediol 1.5g, carbomer 0.3g, sodium hydroxide 0.2g, caprylyl glycol 0.15g, beta glucan 0.002g, hydrolyzed vegetable protein 0.00025g, adenosine triphosphate 0.00025g, sodium chondroitin sulfate 0.00025g, resveratrol 0.0002g, Flos Chrysanthemi extract 0.0001g, maltodextrin 0.0001g, denatonium benzoate 0.00002g, soluble protein polysaccharide 0.000005g, prunus mume (sieb.) sieb.et zucc. berry extract 0.000004g, Cynara scolymus L (Cyhara cardunculus.) leaf extract 0.0000004g, Citrus junos fruit extract 0.0000003g, artemia extract 0.0000002g, platinum powder 0.0000002g, Tremella extract 0.05g, Glycyrrhiza glabra L. root extract 0.05g, two-PEG-18 methyl ether dimethylsilane 0.5g.
The preparation method of gel is:
(1) fetch water 62g, betanin, glycerol 1.2g, 1,3-butanediol 1.2g, 1, ammediol, 1,2-propylene glycol, 1,2-hexanediol 0.6g, two-PEG-18 methyl ether dimethylsilane, caprylyl glycol, carbomer, add aqueous phase pot, after being heated to 80-85 DEG C, stir, in suction vacuum emulsifying machine;
(2) start is uniformly mixed, and 30 minutes, 1000rpm/ divided, and stops stirring, is cooled to 40 DEG C; Add water 15.3g, glycerol 1.8g, 1,2-hexanediol 0.9,1,2-pentanediol, beta glucan, Glycyrrhiza glabra L. root extract, sodium hydroxide, Tremella extract, 1,3-butanediol 1.8g, hydrolyzed vegetable protein, adenosine triphosphate, sodium chondroitin sulfate, artemia extract, platinum powder, Citrus junos fruit extract, soluble protein polysaccharide, Cynara scolymus L (Cyhara cardunculus.) leaf extract, prunus mume (sieb.) sieb.et zucc. berry extract, resveratrol, maltodextrin, Flos Chrysanthemi extract, denatonium benzoate, continue to stir, be cooled to room temperature; Fill, to obtain final product.
Test 2 groups: betanin 5g, glycerol 3g, 1, 2-pentanediol 3g, 1, 3-butanediol 3g, 1, 2-propylene glycol 3g, 1, ammediol 3g, 1, 2-hexanediol 1.5g, carbomer 0.3g, sodium carbonate 0.5g, caprylyl glycol 0.15g, beta glucan 0.002g, hydrolyzed vegetable protein 0.00025g, adenosine triphosphate 0.00025g, sodium chondroitin sulfate 0.00025g, resveratrol 0.0002g, Flos Chrysanthemi extract 0.0001g, maltodextrin 0.0001g, denatonium benzoate 0.00002g, soluble protein polysaccharide 0.000005g, prunus mume (sieb.) sieb.et zucc. berry extract 0.000004g, Cynara scolymus L (Cyhara cardunculus.) leaf extract 0.0000004g, Citrus junos fruit extract 0.0000003g, artemia extract 0.0000002g, platinum powder 0.0000002g, Tremella extract 0.05g, Glycyrrhiza glabra L. root extract 0.05g, two-PEG-18 methyl ether dimethylsilane 0.5g.
The preparation method of gel is:
(1) fetch water 62g, betanin, glycerol 1.2g, 1,3-butanediol 1.2g, 1, ammediol, 1,2-propylene glycol, 1,2-hexanediol 0.6g, two-PEG-18 methyl ether dimethylsilane, caprylyl glycol, carbomer, add aqueous phase pot, after being heated to 80-85 DEG C, stir, in suction vacuum emulsifying machine;
(2) start is uniformly mixed, and 30 minutes, 1000rpm/ divided, and stops stirring, is cooled to 40 DEG C; Add water 15.3g, glycerol 1.8g, 1,2-hexanediol 0.9,1,2-pentanediol, beta glucan, Glycyrrhiza glabra L. root extract, sodium carbonate, Tremella extract, 1,3-butanediol 1.8g, hydrolyzed vegetable protein, adenosine triphosphate, sodium chondroitin sulfate, artemia extract, platinum powder, Citrus junos fruit extract, soluble protein polysaccharide, Cynara scolymus L (Cyhara cardunculus.) leaf extract, prunus mume (sieb.) sieb.et zucc. berry extract, resveratrol, maltodextrin, Flos Chrysanthemi extract, denatonium benzoate, continue to stir, be cooled to room temperature; Fill, to obtain final product.
Conclusion (of pressure testing): in table 4.
Table 4 stability test result
| Group | Whether layering | Whether oil slick | Whether color and luster changes |
| Test 1 group | No | No | No |
| Test 2 groups | Have | Have | No |
Conclusion (of pressure testing): gel of the present invention does not produce the phenomenon that layering, oil slick and color and luster change, and absolutely proves that gel prescription stability of the present invention is better.
Preparation embodiment
Embodiment 1
Gel prescription is: betanin 4g, glycerol 2g, 1, 2-pentanediol 2g, 1, 3-butanediol 2g, 1, 2-propylene glycol 2g, 1, ammediol 2g, 1, 2-hexanediol 1g, carbomer 0.2g, sodium hydroxide 0.1g, caprylyl glycol 0.1g, beta glucan 0.001g, hydrolyzed vegetable protein 0.0002g, adenosine triphosphate 0.0002g, sodium chondroitin sulfate 0.0002g, resveratrol 0.0001g, Flos Chrysanthemi extract 0.0001g, maltodextrin 0.0001g, denatonium benzoate 0.00002g, soluble protein polysaccharide 0.000005g, prunus mume (sieb.) sieb.et zucc. berry extract 0.000004g, Cynara scolymus L (Cyhara cardunculus.) leaf extract 0.0000004g, Citrus junos fruit extract 0.0000003g, artemia extract 0.0000002g, platinum powder 0.0000002g, Tremella extract 0.04g, Glycyrrhiza glabra L. root extract 0.04g, two-PEG-18 methyl ether dimethylsilane 0.4g.
The preparation method of gel is:
(1) fetch water 50g, betanin, glycerol 0.8g, 1,3-butanediol 0.8g, 1, ammediol, 1,2-propylene glycol, 1,2-hexanediol 0.4g, two-PEG-18 methyl ether dimethylsilane, caprylyl glycol, carbomer, add aqueous phase pot, after being heated to 80-85 DEG C, stir, in suction vacuum emulsifying machine;
(2) start is uniformly mixed, and 30 minutes, 1000rpm/ divided, stop stirring, be cooled to 40 DEG C; Add water 11.6g, glycerol 1.2g, 1,2-hexanediol 0.6g, 1,2-pentanediol, beta glucan, Glycyrrhiza glabra L. root extract, sodium hydroxide, Tremella extract, 1,3-butanediol 1.2g, hydrolyzed vegetable protein, adenosine triphosphate, sodium chondroitin sulfate, artemia extract, platinum powder, Citrus junos fruit extract, soluble protein polysaccharide, Cynara scolymus L (Cyhara cardunculus.) leaf extract, prunus mume (sieb.) sieb.et zucc. berry extract, resveratrol, maltodextrin, Flos Chrysanthemi extract, denatonium benzoate, continue to stir, be cooled to room temperature; Fill, to obtain final product.
Embodiment 2
Gel prescription is: betanin 5g, glycerol 3g, 1, 2-pentanediol 3g, 1, 3-butanediol 3g, 1, 2-propylene glycol 3g, 1, ammediol 3g, 1, 2-hexanediol 1.5g, carbomer 0.3g, sodium hydroxide 0.2g, caprylyl glycol 0.15g, beta glucan 0.002g, hydrolyzed vegetable protein 0.00025g, adenosine triphosphate 0.00025g, sodium chondroitin sulfate 0.00025g, resveratrol 0.0002g, Flos Chrysanthemi extract 0.0001g, maltodextrin 0.0001g, denatonium benzoate 0.00002g, soluble protein polysaccharide 0.000005g, prunus mume (sieb.) sieb.et zucc. berry extract 0.000004g, Cynara scolymus L (Cyhara cardunculus.) leaf extract 0.0000004g, Citrus junos fruit extract 0.0000003g, artemia extract 0.0000002g, platinum powder 0.0000002g, Tremella extract 0.05g, Glycyrrhiza glabra L. root extract 0.05g, two-PEG-18 methyl ether dimethylsilane 0.5g.
The preparation method of gel is:
(1) fetch water 62g, betanin, glycerol 1.2g, 1,3-butanediol 1.2g, 1, ammediol, 1,2-propylene glycol, 1,2-hexanediol 0.6g, two-PEG-18 methyl ether dimethylsilane, caprylyl glycol, carbomer, add aqueous phase pot, after being heated to 80-85 DEG C, stir, in suction vacuum emulsifying machine;
(2) start is uniformly mixed, and 30 minutes, 1000rpm/ divided, and stops stirring, is cooled to 40 DEG C; Add water 15.3g, glycerol 1.8g, 1,2-hexanediol 0.9,1,2-pentanediol, beta glucan, Glycyrrhiza glabra L. root extract, sodium hydroxide, Tremella extract, 1,3-butanediol 1.8g, hydrolyzed vegetable protein, adenosine triphosphate, sodium chondroitin sulfate, artemia extract, platinum powder, Citrus junos fruit extract, soluble protein polysaccharide, Cynara scolymus L (Cyhara cardunculus.) leaf extract, prunus mume (sieb.) sieb.et zucc. berry extract, resveratrol, maltodextrin, Flos Chrysanthemi extract, denatonium benzoate, continue to stir, be cooled to room temperature; Fill, to obtain final product.
Embodiment 3
Gel prescription is: betanin 6g, glycerol 4g, 1, 2-pentanediol 4g, 1, 3-butanediol 4g, 1, 2-propylene glycol 4g, 1, ammediol 4g, 1, 2-hexanediol 2g, carbomer 0.4g, sodium hydroxide 0.3g, caprylyl glycol 0.2g, beta glucan 0.003g, hydrolyzed vegetable protein 0.0003g, adenosine triphosphate 0.0003g, sodium chondroitin sulfate 0.0003g, resveratrol 0.0003g, Flos Chrysanthemi extract 0.0001g, maltodextrin 0.0001g, denatonium benzoate 0.00002g, soluble protein polysaccharide 0.000005g, prunus mume (sieb.) sieb.et zucc. berry extract 0.000004g, Cynara scolymus L (Cyhara cardunculus.) leaf extract 0.0000004g, Citrus junos fruit extract 0.0000003g, artemia extract 0.0000002g, platinum powder 0.0000002g, Tremella extract 0.06g, Glycyrrhiza glabra L. root extract 0.06g, two-PEG-18 methyl ether dimethylsilane 0.6g.
The preparation method of gel is:
(1) fetch water 77g, betanin, glycerol 1.6g, 1,3-butanediol 1.6g, 1, ammediol, 1,2-propylene glycol, 1,2-hexanediol 0.8g, two-PEG-18 methyl ether dimethylsilane, caprylyl glycol, carbomer, add aqueous phase pot, after being heated to 80-85 DEG C, stir, in suction vacuum emulsifying machine;
(2) start is uniformly mixed, and 30 minutes, 1000rpm/ divided, and stops stirring, is cooled to 40 DEG C; Add water 18.1g, glycerol 2.4g, 1,2-hexanediol 1.2g, 1,2-pentanediol, beta glucan, Glycyrrhiza glabra L. root extract, sodium hydroxide, Tremella extract, 1,3-butanediol 2.4g, hydrolyzed vegetable protein, adenosine triphosphate, sodium chondroitin sulfate, artemia extract, platinum powder, Citrus junos fruit extract, soluble protein polysaccharide, Cynara scolymus L (Cyhara cardunculus.) leaf extract, prunus mume (sieb.) sieb.et zucc. berry extract, resveratrol, maltodextrin, Flos Chrysanthemi extract, denatonium benzoate, continue to stir, be cooled to room temperature; Fill, to obtain final product.
Preparation embodiment includes but not limited to above-mentioned.
Claims (6)
1. a gel, is characterized in that gel contains Tremella extract, Glycyrrhiza glabra L. root extract, two-PEG-18 methyl ether dimethylsilane.
2. a kind of gel according to claim 1, wherein Tremella extract 0.04-0.06 weight portion, Glycyrrhiza glabra L. root extract 0.04-0.06 weight portion, two-PEG-18 methyl ether dimethylsilane 0.4-0.6 weight portion.
3. a kind of gel according to claim 1 and 2, is characterized in that the application of compositions in skin-lightening cosmetic of Tremella extract, Glycyrrhiza glabra L. root extract and two-PEG-18 methyl ether dimethylsilane.
4. a kind of gel according to claim 1, the raw material wherein preparing gel comprises: betanin, glycerol, 1, 2-pentanediol, 1, 3-butanediol, 1, 2-propylene glycol, 1, ammediol, 1, 2-hexanediol, carbomer, sodium hydroxide, caprylyl glycol, beta glucan, hydrolyzed vegetable protein, adenosine triphosphate, sodium chondroitin sulfate, resveratrol, Flos Chrysanthemi extract, maltodextrin, denatonium benzoate, soluble protein polysaccharide, prunus mume (sieb.) sieb.et zucc. berry extract, Cynara scolymus L (Cyhara cardunculus.) leaf extract, Citrus junos fruit extract, artemia extract, platinum powder, Tremella extract, Glycyrrhiza glabra L. root extract, two-PEG-18 methyl ether dimethylsilane.
5. a kind of gel according to claim 1, the raw material wherein preparing gel comprises: betanin 4-6 weight portion, glycerol 2-4 weight portion, 1,2-pentanediol 2-4 weight portion, 1,3 butylene glycol 2-4 weight portion, 1,2-PD 2-4 weight portion, 1,3-PD 2-4 weight portion, 1,2-hexanediol 1-2 weight portion, carbomer 0.2-0.4 weight portion, sodium hydroxide 0.1-0.3 weight portion, caprylyl glycol 0.1-0.2 weight portion, beta glucan 0.001-0.003 weight portion, hydrolyzed vegetable protein 0.0002-0.0003 weight portion, adenosine triphosphate 0.0002-0.0003 weight portion, sodium chondroitin sulfate 0.0002-0.0003 weight portion, resveratrol 0.0001-0.0003 weight portion, Flos Chrysanthemi extract 0.0001 weight portion, maltodextrin 0.0001 weight portion, denatonium benzoate 0.00002 weight portion, soluble protein polysaccharide 0.000005 weight portion, prunus mume (sieb.) sieb.et zucc. berry extract 0.000004 weight portion, Cynara scolymus L (Cyhara cardunculus.) leaf extract 0.0000004 weight portion, Citrus junos fruit extract 0.0000003 weight portion, artemia extract 0.0000002 weight portion, platinum powder 0.0000002 weight portion, Tremella extract 0.04-0.06 weight portion, Glycyrrhiza glabra L. root extract 0.04-0.06 weight portion, two-PEG-18 methyl ether dimethylsilane 0.4-0.6 weight portion.
6. a kind of gel according to claim 5, is characterized in that the preparation method of gel is:
(1) water intaking, betanin, glycerol, 1,3 butylene glycol, 1,3-PD, 1,2-propylene glycol, 1,2-hexanediol, two-PEG-18 methyl ether dimethylsilane, caprylyl glycol, carbomer, add aqueous phase pot, after being heated to 80-85 DEG C, stir, in suction vacuum emulsifying machine;
(2) start is uniformly mixed, and 30 minutes, 1000rpm/ divided, and stops stirring, is cooled to 40 DEG C; Add water, glycerol, 1,2-hexanediol, 1,2-pentanediol, beta glucan, Glycyrrhiza glabra L. root extract, sodium hydroxide, Tremella extract, 1,3-butanediol, hydrolyzed vegetable protein, adenosine triphosphate, sodium chondroitin sulfate, artemia extract, platinum powder, Citrus junos fruit extract, soluble protein polysaccharide, Cynara scolymus L (Cyhara cardunculus.) leaf extract, prunus mume (sieb.) sieb.et zucc. berry extract, resveratrol, maltodextrin, Flos Chrysanthemi extract, denatonium benzoate, continue to stir, be cooled to room temperature; Fill, to obtain final product.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108283587A (en) * | 2017-01-10 | 2018-07-17 | 北京城市学院 | A kind of glycyrrhizic acid whitening moisture-retention gel and preparation method thereof |
| CN109937029A (en) * | 2017-04-24 | 2019-06-25 | 汤姆凯特国际有限公司 | The combination and method of anti-aging sign |
| CN112315890A (en) * | 2020-11-24 | 2021-02-05 | 北京鸣聚力商贸有限责任公司 | Whitening and skin-brightening composition and preparation method and application thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102860975A (en) * | 2012-08-31 | 2013-01-09 | 马应龙药业集团股份有限公司 | Skin-whitening and moisture-preserving skin-care product for eyes and preparation method for skin-whitening and moisture-preserving skin-care product |
| CN104306319A (en) * | 2014-10-30 | 2015-01-28 | 郑州市嘉蓓丽生物科技有限公司 | Ghee whitening skin cream and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102860975A (en) * | 2012-08-31 | 2013-01-09 | 马应龙药业集团股份有限公司 | Skin-whitening and moisture-preserving skin-care product for eyes and preparation method for skin-whitening and moisture-preserving skin-care product |
| CN104306319A (en) * | 2014-10-30 | 2015-01-28 | 郑州市嘉蓓丽生物科技有限公司 | Ghee whitening skin cream and preparation method thereof |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108283587A (en) * | 2017-01-10 | 2018-07-17 | 北京城市学院 | A kind of glycyrrhizic acid whitening moisture-retention gel and preparation method thereof |
| CN109937029A (en) * | 2017-04-24 | 2019-06-25 | 汤姆凯特国际有限公司 | The combination and method of anti-aging sign |
| CN112315890A (en) * | 2020-11-24 | 2021-02-05 | 北京鸣聚力商贸有限责任公司 | Whitening and skin-brightening composition and preparation method and application thereof |
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Address after: 511434 No. 13, No. 1, Liu Wei street, Hualong Town, Panyu District, Guangzhou, Guangdong. Patentee after: Hua An Tang biotech Group Co., Ltd. Address before: 511434 No. 13, No. 1, Liu Wei street, Hualong Town, Panyu District, Guangzhou, Guangdong. Patentee before: City flower An Tang bio tech ltd, Guangzhou |
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