CN109846772A - A kind of composition with white-skinned face function, skin care item and preparation method thereof - Google Patents
A kind of composition with white-skinned face function, skin care item and preparation method thereof Download PDFInfo
- Publication number
- CN109846772A CN109846772A CN201811081603.3A CN201811081603A CN109846772A CN 109846772 A CN109846772 A CN 109846772A CN 201811081603 A CN201811081603 A CN 201811081603A CN 109846772 A CN109846772 A CN 109846772A
- Authority
- CN
- China
- Prior art keywords
- white
- face function
- skinned face
- composition
- phase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
The present invention relates to cosmetic technical fields, more particularly to a kind of composition with white-skinned face function, skin care item and preparation method thereof, on the basis of medicinal material dry weight, the composition with white-skinned face function is made of raw material from the following weight: 1 ~ 20 part of apple, 1 ~ 20 part of tree peony, 1 ~ 20 part of Radix Glycyrrhizae, 1 ~ 20 part and 1 ~ 20 part of ginseng of Radix Paeoniae Alba.The present invention passes through apple, tree peony, Radix Glycyrrhizae, the mutual aid collaboration of five kinds of natural constituents of Radix Paeoniae Alba and ginseng, compounding forms composition, dermal melanin can be reduced from number of ways, and have a variety of effects to skin, synergy reaches skin whitening, the more potent whitening function such as facial colour spot reduction.
Description
Technical field
The present invention relates to cosmetic technical field more particularly to a kind of composition with white-skinned face function, skin care item and its
Preparation method.
Background technique
If Asia women pursues always the white congealed fat of skin.However since work rhythm is fast, psychological pressure is big, endocrine is lost
Phenomena such as influence of the internal and external factors such as tune, environmental pollution, skin also accordingly will appear obscure, pigmentation, therefore whitening is skin
Skin nurses one of most important theme.
Usually said melanin is primarily referred to as excellent melanocyte and pheomelanin.Modern beauty medicine shows that melanin is to pass through
What a series of oxidation reactions were formed: tyrosinase, dopachrome tautomerase, 5,6- dihydroxy indole carboxylic oxidase this
Under the participation of three kinds of enzyme different phases, the tyrosine in melanocyte generates 5,6- dihydroxy indole carboxylic by series reaction
Acid is to form excellent melanocyte；Intermediate product DOPA meanwhile under the catalysis of cysteine or glutathione, in above-mentioned reaction process
Quinone is converted into cysteinyl dopa or glutathione DOPA, ultimately produces pheomelanin.In turn, melanocyte tissue is by black
Element is transferred in Epidermal basal layer cells, is brought in cuticula with the metabolism of cell, finally with keratinocyte
It falls off.
There are many mechanism of skin-whitening, such as: defence ultraviolet radiation inhibits tyrosinase/DOPA in melanocyte
Interconvertible enzyme and 5,6- dihydroxy indole carboxylic acid oxidative enzymatic activity improve body superoxide dismutase activity and remove extra super oxygen certainly
Updated by base, the transfer of inhibition melanocyte, promotion horn cell etc..
Currently, the whitening additive mechanism used in cosmetic product is more single, mainly to inhibit tyrosine enzyme activity
Property based on, lack number of mechanisms integrated use and in order to develop effect skin-lightening cosmetic more outstanding then need number of mechanisms
Integrated use preferably to achieve the purpose that skin whitening.
Summary of the invention
The present invention provides one kind and is compounded by natural plant extracts to overcome above-mentioned problems of the prior art
Made of the composition with white-skinned face function, dermal melanin can be reduced from number of ways, and there are a variety of benefits to skin
Benefit effect.
The present invention also provides a kind of preparation methods of composition with white-skinned face function, and this method process conditions are mild,
Recovery rate is high, to equipment without particular/special requirement, is conducive to large-scale industrialized production.
The present invention also provides a kind of skin care item with white-skinned face function.
The present invention also provides a kind of preparation methods of skin care item with white-skinned face function.
To achieve the goals above, the invention adopts the following technical scheme:
A kind of composition with white-skinned face function, on the basis of medicinal material dry weight, the composition with white-skinned face function is by following
The raw material of parts by weight is made: 1 ~ 20 part of apple, 1 ~ 20 part of tree peony, 1 ~ 20 part of Radix Glycyrrhizae, 1 ~ 20 part and 1 ~ 20 part of ginseng of Radix Paeoniae Alba.
It is rich in flavones ingredient in apple root skin, has and eliminates DPPH and inhibit tyrosinase activity, inhibits melanin raw
At wherein phloretin can also significantly improve the spf value of formula, have superior ultraviolet radiation protective effect.Therefore apple root skin
Extract has whitening and delaying senility function.Cortex moutan has clearing heat and cooling blood, the effect of activating microcirculation and removing stasis medicinal, rich in phenolic acid class at
Point, wherein Paeonol has the nucleus formation for significantly inhibiting tyrosinase activity and inhibition melanin in melanocyte, while can
To inhibit the melanin in melanocyte to transport, while the inflammatory factors such as IL-6, PGE-2 in human keratinized cell can be inhibited to generate,
Therefore moutan root bark extract has whitening and anti-inflammatory effect simultaneously.Radix Glycyrrhizae, which has, invigorates the spleen and benefits qi, clearing heat and detoxicating, expelling phlegm and arresting coughing,
Relieving spasm to stop pain effect, root are rich in flavones ingredient, referred to as whitening gold, have and inhibit tyrosine enzyme activity in melanocyte
Property, inhibit the effect of melanin production, can additionally inhibit DPPH to generate, inhibit caused by UVB IL-10 in HaCaT cell
And the expression of the inflammatory factors such as TNF-α, have effects that qualified skin nursing.Radix Paeoniae Alba have calming the liver and relieving pain, nourishing blood for regulating menstruation,
The effect of astringing YIN to stop sweating, root are rich in monoterpene and its glucosides constituents, such as total glucosides of paeony can inhibit external tyrosinase
Activity and a variety of free radicals such as remove DPPH, while there is whitening function of delaying senility.Ginseng, which has, to reinforce vital energy, and multiple arteries and veins is solid
It is de-, reinforce the spleen to benefit the lung and other effects, root is rich in a variety of saponin components, has whitening wrinkle-removing delaying senility function.Such as ginseng
Total saposins can inhibit external tyrosinase activity, and ginsenoside Rb1 and Rg1 can inhibit outside fibroblast caused by UVB
The generation of mmp-1, the reduction of I procollagen type and elastin laminin.
It is black to reduce skin from number of ways for composition made of compounding of the present invention by above-mentioned plant extracts
Pigment, and there are a variety of effects to skin, therefore, the composition can more effectively play the effect of whitening.
A kind of preparation method of the composition with white-skinned face function, comprising the following steps:
(1) medicinal material is weighed according to said ratio, ethanol water dipping is added in grinds；
(2) diacolation collects percolate；
(3) the resulting percolate of step (2) is concentrated, obtains concentrate, 1,2-PD is added in concentrate, stirs evenly,
The composition being stirred is de-gassed, using vacuum outgas, the bubble formed in whipping process is removed, stands to get tool
There is the composition of white-skinned face function.
Preferably, the volumetric concentration of the ethanol water is 50 ~ 95% in step (1)；The ethanol water
Additional amount is 5 ~ 20 times of amounts, and described times of amount is volume/medicinal material weight [liquor capacity (ml): medicinal material weight of ethanol water
(g)]。
Preferably, dip time is controlled in 12 ~ 48h in step (1).
Preferably, diacolation speed control is in 1 ~ 10mL/min in step (2)；The volume of collected percolate is medicinal material
10 ~ 20 times of amount.
Preferably, cycles of concentration is 10 ~ 50 times in step (3)；The additional amount of 1,2- propylene glycol is the volume of the concentrated liquid
0.5 ~ 3 times；Time of repose is for 24 hours.
It is a kind of to include the above-mentioned skin care item with white-skinned face function composition.
A kind of preparation method of the skin care item with white-skinned face function, comprising the following steps:
(1) by weight, 1 ~ 10 part of butanediol is mixed with 0.1 ~ 0.5 part of thickener, obtains A phase；
(2) by 0.01 ~ 0.05 part of EDETATE SODIUM, 0.1 ~ 0.5 part of triethanolamine, 1 ~ 10 part of biology carbohydrate gum Gioactive F-
1000,1 ~ 10 part of ethoxy urea Gmoist HEU, 1 ~ 10 part of plant Shu Min agent Comthing SGS, 0.1 ~ 0.5 part of oxybenzene first
Ester and 0.1 ~ 0.5 part of 1,2- pentanediol are dissolved in water, are uniformly mixed, obtain B phase；By B heat phase to 80 ~ 85 DEG C, stir evenly；
(3) the A phase that step (1) obtains is mixed with the B after heating in step (2), 80 ~ 85 DEG C of heat preservation 5min, then homogeneous
Stirring, is uniformly dispersed, obtains C phase；
(4) 0.1 ~ 0.5 part of Cremophor RH40 is mixed with 0.01 ~ 0.5 part of essence, homogeneous stirring is uniformly dispersed, obtains
D phase；
(5) C phase is cooled to 50 DEG C or so, 1 ~ 5 part of composition described in claim 1 with white-skinned face function is added,
Continue stirring to 40 DEG C, the D phase that step (4) obtain then is added, stirs evenly, discharges to get the skin care with white-skinned face function
Product.
Preferably, the thickener is that acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters crosslinking is poly- in step (1)
Close object.
Therefore, the invention has the following beneficial effects:
(1) present invention is cooperateed with by apple, the mutual aid of tree peony, Radix Glycyrrhizae, five kinds of natural constituents of Radix Paeoniae Alba and ginseng, and compounding forms combination
Object can reduce dermal melanin from number of ways, and have a variety of effects to skin, and synergy reaches skin whitening,
The more potent whitening functions such as facial colour spot reduction；
(2) preparation process condition of the invention is mild, and recovery rate is high, and to equipment without particular/special requirement, preparation cost is low, is conducive to big
Scale industrialization production；
(3) composition with white-skinned face function of the invention has broad application prospects, can be direct directly as whitening product
It uses, it can also application by reasonably combined with other kinds effective component, for all kinds of cosmetics.
Detailed description of the invention
Fig. 1 is that the oxidative damage of GL2-2, VCE and Arbutin resistance 1600 mJ UVB induction compares figure.
Fig. 2 is inhibiting effect figure of the various concentration GL2-2 for the UVB melanin production induced.
Specific embodiment
Below by specific embodiment, and in conjunction with attached drawing, the technical solutions of the present invention will be further described.
In the present invention, if not refering in particular to, all devices and raw material is commercially available or the industry is common are following
Method in embodiment is unless otherwise instructed conventional method in that art.
Biological carbohydrate gum is purchased from GREAF company, and product type is Gioactive F-1000；
Ethoxy urea is purchased from GREAF company, and product type is Gmoist HEU；
Plant Shu Min agent is purchased from GREAF company, and product type is Comthing SGS.
Embodiment 1
Prepare the composition with white-skinned face function:
(1) dry medicinal material: apple 20g, tree peony 20g, Radix Glycyrrhizae 20g, Radix Paeoniae Alba 20g and ginseng 20g are weighed according to following proportion, worn into
Powder is added the ethanol water that 20 times of amounts [liquor capacity (ml): medicinal material weight (g)] volumetric concentration is 50% and impregnates 48h；
(2) diacolation is started with the speed of 1mL/min, collects the percolate volume (ml) of 20 times of medicinal material amounts；
(3) percolate is concentrated 10 times, then plus 0.5 times of 1,2-PD, stir evenly, stand 24 hours to get having beauty
The composition of contour painting effect.
Prepare the skin care item with white-skinned face function:
(1) 5g butanediol is mixed with 0.3g acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross-linked polymer, obtains A phase；
(2) by 0.02gEDTA disodium, 0.3g triethanolamine, 5g biology carbohydrate gum, 6g ethoxy urea, 8g plant Shu Min agent, 0.4g
Methyl hydroxybenzoate and 0.3g1,2- pentanediol are dissolved in water, are uniformly mixed, obtain B phase；By B heat phase to 82 DEG C, stir evenly；
(3) the A phase that step (1) obtains is mixed with the B after heating in step (2), 83 DEG C of heat preservation 5min, then homogeneous stirs
It mixes, is uniformly dispersed, obtain C phase；
(4) 0.5g Cremophor RH40 is mixed with 0.01g essence, homogeneous stirring is uniformly dispersed, obtains D phase；
(5) C phase is cooled to 50 DEG C or so, the 1g composition described in claim 1 with white-skinned face function is added, continued
Then stirring is added the D phase that step (4) obtain, stirs evenly, discharge to get the skin care item with white-skinned face function to 40 DEG C.
Embodiment 2
Prepare the composition with white-skinned face function:
(1) dry medicinal material: apple 1g, tree peony 20g, Radix Glycyrrhizae 1g, Radix Paeoniae Alba 10g and ginseng 1g are weighed according to following proportion；Grinds add
Enter the ethanol water that 5 times of amounts [liquor capacity (ml): medicinal material weight (g)] volumetric concentration is 95% and impregnates 12h；
(2) diacolation is started with the speed of 10mL/min, collects the percolate volume (ml) of 10 times of medicinal material amounts；
(3) percolate is concentrated 50 times, then plus 3 times of 1,2-PD, stir evenly, stand 24 hours to get with whitening
The composition of effect.
Prepare the skin care item with white-skinned face function:
(1) 1g butanediol is mixed with 0.5g acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross-linked polymer, obtains A phase；
(2) by 0.01g EDETATE SODIUM, 0.1g triethanolamine, 10g biology carbohydrate gum, 1g ethoxy urea, 1g plant Shu Min agent,
0.5g methyl hydroxybenzoate and 0.5g 1,2- pentanediol are dissolved in water, are uniformly mixed, obtain B phase；By B heat phase to 80 DEG C, stirring is equal
It is even；
(3) the A phase that step (1) obtains is mixed with the B after heating in step (2), 80 DEG C of heat preservation 5min, then homogeneous stirs
It mixes, is uniformly dispersed, obtain C phase；
(4) 0.1g Cremophor RH40 is mixed with 0.5g essence, homogeneous stirring is uniformly dispersed, obtains D phase；
(5) C phase is cooled to 50 DEG C or so, the above-mentioned composition with white-skinned face function of 5g is added, continue stirring to 40
DEG C, the D phase that step (4) obtain then is added, stirs evenly, discharges to get the skin care item with white-skinned face function.
Embodiment 3
Prepare the composition with white-skinned face function:
(1) dry medicinal material: apple 10g, tree peony 1g, Radix Glycyrrhizae 10g, Radix Paeoniae Alba 1g and ginseng 15g: grinds are weighed according to following proportion,
The ethanol water that 15 times of amounts [liquor capacity (ml): medicinal material weight (g)] volumetric concentration is 85% is added to impregnate for 24 hours；
(2) diacolation is started with the speed of 5mL/min, collects the percolate volume (ml) of 15 times of medicinal material amounts；
(3) percolate is concentrated 35 times, then plus 2 times of 1,2-PD, stir evenly, stand 24 hours to get with whitening
The composition of effect.
Prepare the skin care item with white-skinned face function:
(1) 10g butanediol is mixed with 0.1g acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross-linked polymer, obtains A
Phase；
(2) by 0.05gEDTA disodium, 0.1g triethanolamine, 10g biology carbohydrate gum, 1g ethoxy urea, 1g plant Shu Min agent,
0.1g methyl hydroxybenzoate and 0.1g 1,2- pentanediol are dissolved in water, are uniformly mixed, obtain B phase；By B heat phase to 85 DEG C, stirring is equal
It is even；
(3) the A phase that step (1) obtains is mixed with the B after heating in step (2), 85 DEG C of heat preservation 5min, then homogeneous stirs
It mixes, is uniformly dispersed, obtain C phase；
(4) 0.4g Cremophor RH40 is mixed with 0.25g essence, homogeneous stirring is uniformly dispersed, obtains D phase；
(5) C phase is cooled to 50 DEG C or so, the above-mentioned composition with white-skinned face function of 4g is added, continue stirring to 40
DEG C, the D phase that step (4) obtain then is added, stirs evenly, discharges to get the skin care item with white-skinned face function.
Comparative example 1
Comparative example 1 uses VCE(VC ethylether) solution.
Comparative example 2
Comparative example 2 uses arbutin (Arbutin) solution.
Composition with white-skinned face function of the invention is denoted as GL2-2.
To GL2-2, comparative example 1(VCE of the invention) and comparative example 2(Arbutin) on clinical pattern effect evaluation,
Experimental program:
Positive control VC and arbutin (Arbutin) are configured to the solution for standby of 100 mg/mL, are inoculated with 1.5 into 96 orifice plates
×104Or 5 × 104Cell concentration, after 24 h, cell is adherent.200~1600 mJ/cm2After UVB irradiation, every hole is added different
The sample to be tested and positive control of concentration, in 37 C, 5% CO224 ~ 72 h of constant incubator culture takes out on 150 μ L cells
Clearly to 96 new orifice plates, melanin content is measured at 405nm in microplate reader, it is living with the method detection cell of red untake
Power, testing result are as depicted in figs. 1 and 2.
Abscissa is the GL2-2 composition and positive control VCE(5mg/ of the active constituent containing various concentration as shown in Figure 1:
ML), arbutin (1mg/mL), ordinate are cell viability (%).1600 mJ/cm as can be seen from Figure 12UVB irradiating cell
Afterwards, 0.75% composition solution (containing 63 μ g/mL active matters) is added, cell viability significantly improves 61%, the bear of 1 mg/ml
The oxidative damage that fruit glycosides cannot protect UVB to induce significantly reduces cell viability to 8.2% instead；The VCE of 5 mg/ml can be fought
1600 mJ/cm2UVB, cell viability can be improved 22%, and function and effect do not have composition effect strong.
As shown in Figure 2: abscissa is the GL2-2 composition of the active constituent containing various concentration, and ordinate is that melanin inhibits
Rate (%).The GL2-2 composition of various concentration can dose-dependently reduce the melanin life of UVB induction as can be seen from Figure 2
At IC50 is respectively 16.2 μ g/mL.
The foregoing is merely presently preferred embodiments of the present invention, is not intended to limit the present invention in any form, and is not surpassing
There are also other variations and modifications under the premise of technical solution documented by claim out.
Claims (9)
1. a kind of composition with white-skinned face function, which is characterized in that described with white-skinned face function on the basis of medicinal material dry weight
Composition is made of raw material from the following weight: 1 ~ 20 part of apple, 1 ~ 20 part of tree peony, and 1 ~ 20 part of Radix Glycyrrhizae, 1 ~ 20 part of Radix Paeoniae Alba and people
1 ~ 20 part of ginseng.
2. a kind of preparation method of the composition with white-skinned face function as described in claim 1, which is characterized in that including following
Step:
(1) medicinal material is weighed according to said ratio, ethanol water dipping is added in grinds；
(2) diacolation collects percolate；
(3) the resulting percolate of step (2) is concentrated, obtains concentrate, 1,2-PD is added in concentrate, stirs evenly,
It stands to get the composition with white-skinned face function.
3. the preparation method of the composition according to claim 2 with white-skinned face function, which is characterized in that in step (1),
The volumetric concentration of the ethanol water is 50 ~ 95%；The additional amount of the ethanol water is 5 ~ 20 times of amounts, and described times of amount is
The volume of ethanol water/medicinal material weight.
4. the preparation method of the composition according to claim 2 with white-skinned face function, which is characterized in that in step (1),
Dip time is controlled in 12 ~ 48h.
5. the preparation method of the composition according to claim 2 with white-skinned face function, which is characterized in that in step (2),
Diacolation speed control is in 1 ~ 10mL/min；The volume of collected percolate is 10 ~ 20 times of medicinal material amount.
6. the preparation method of the composition according to claim 2 with white-skinned face function, which is characterized in that in step (3),
Cycles of concentration is 10 ~ 50 times；The additional amount of 1,2- propylene glycol is 0.5 ~ 3 times of the volume of the concentrated liquid；Time of repose is for 24 hours.
7. a kind of skin care item with white-skinned face function, which is characterized in that the skin care item with white-skinned face function include such as right
It is required that with the composition of white-skinned face function described in 1.
8. a kind of preparation method of the skin care item with white-skinned face function as claimed in claim 7, which is characterized in that including following
Step:
(1) by weight, 1 ~ 10 part of butanediol is mixed with 0.1 ~ 0.5 part of thickener, obtains A phase；
(2) by 0.01 ~ 0.05 part of EDETATE SODIUM, 0.1 ~ 0.5 part of triethanolamine, 1 ~ 10 part of biological carbohydrate gum, 1 ~ 10 part of ethoxy urine
Element, 1 ~ 10 part of plant Shu Min agent, 0.1 ~ 0.5 part of methyl hydroxybenzoate and 0.1 ~ 0.5 part of 1,2- pentanediol are dissolved in water, are uniformly mixed, obtain
To B phase；By B heat phase to 80 ~ 85 DEG C, stir evenly；
(3) the A phase that step (1) obtains is mixed with the B after heating in step (2), 80 ~ 85 DEG C of heat preservation 5min, then homogeneous
Stirring, is uniformly dispersed, obtains C phase；
(4) 0.1 ~ 0.5 part of Cremophor RH40 is mixed with 0.01 ~ 0.5 part of essence, homogeneous stirring is uniformly dispersed, obtains
D phase；
(5) C phase is cooled to 50 DEG C or so, 1 ~ 5 part of composition described in claim 1 with white-skinned face function is added,
Continue stirring to 40 DEG C, the D phase that step (4) obtain then is added, stirs evenly, discharges to get the skin care with white-skinned face function
Product.
9. the preparation method of the skin care item according to claim 8 with white-skinned face function, which is characterized in that in step (1),
The thickener is acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross-linked polymer.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811081603.3A CN109846772A (en) | 2018-10-29 | 2018-10-29 | A kind of composition with white-skinned face function, skin care item and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811081603.3A CN109846772A (en) | 2018-10-29 | 2018-10-29 | A kind of composition with white-skinned face function, skin care item and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109846772A true CN109846772A (en) | 2019-06-07 |
Family
ID=66889711
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811081603.3A Pending CN109846772A (en) | 2018-10-29 | 2018-10-29 | A kind of composition with white-skinned face function, skin care item and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109846772A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114209628A (en) * | 2022-01-10 | 2022-03-22 | 山东花物堂生物科技有限公司 | Plant extract composition with whitening effect and application thereof |
| CN115068391A (en) * | 2022-08-05 | 2022-09-20 | 维怡美生物科技(广州)有限公司 | Whitening composition, and whitening essence and whitening lotion containing same |
Citations (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1215326A (en) * | 1996-04-01 | 1999-04-28 | 花王株式会社 | Skin color improver |
| CN1485024A (en) * | 2002-09-28 | 2004-03-31 | 戚海波 | Bee honey and its use in beautifying cosmetics |
| WO2008004685A1 (en) * | 2006-07-04 | 2008-01-10 | Showa Denko K.K. | Emulsion composition |
| CN102058504A (en) * | 2009-11-11 | 2011-05-18 | 日本乐敦制药株式会社 | Anti-saccharification agent |
| WO2011143254A2 (en) * | 2010-05-10 | 2011-11-17 | Segetis, Inc. | Personal care formulations containing alkyl ketal esters and methods of manufacture |
| CN103536468A (en) * | 2013-10-12 | 2014-01-29 | 广州环亚化妆品科技有限公司 | Traditional Chinese medicine composition with whitening effect and application of traditional Chinese medicine composition in cosmetics |
| CN103932970A (en) * | 2014-04-30 | 2014-07-23 | 温州市姿妃韵化妆品有限公司 | Chinese herbal medicine freckle-removal compound cosmetic and preparation method thereof |
| CN104523490A (en) * | 2014-12-11 | 2015-04-22 | 广州栋方日化有限公司 | Exfoliate composition with whitening and moisturizing effects and preparation method of exfoliate composition |
| KR20160055597A (en) * | 2014-11-10 | 2016-05-18 | 이동희 | The composition of functional cosmetics containing silicic acid |
| CN105769652A (en) * | 2016-03-01 | 2016-07-20 | 苏州艾缇克药物化学有限公司 | Apple facial mask based on traditional Chinese medicine formula |
| CN106852823A (en) * | 2015-12-09 | 2017-06-16 | 张延霞 | A kind of Chinese medicine pox-eliminating whitening facial mask and preparation method thereof |
| KR20170138709A (en) * | 2016-06-08 | 2017-12-18 | 주식회사 코스앤코 | A soap composition for traditional oriental |
| CN107737272A (en) * | 2017-12-03 | 2018-02-27 | 同济大学 | A kind of Chinese medicine composition and its methods for making and using same with freckle removing and whitening effect |
-
2018
- 2018-10-29 CN CN201811081603.3A patent/CN109846772A/en active Pending
Patent Citations (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1215326A (en) * | 1996-04-01 | 1999-04-28 | 花王株式会社 | Skin color improver |
| CN1485024A (en) * | 2002-09-28 | 2004-03-31 | 戚海波 | Bee honey and its use in beautifying cosmetics |
| WO2008004685A1 (en) * | 2006-07-04 | 2008-01-10 | Showa Denko K.K. | Emulsion composition |
| CN102058504A (en) * | 2009-11-11 | 2011-05-18 | 日本乐敦制药株式会社 | Anti-saccharification agent |
| WO2011143254A2 (en) * | 2010-05-10 | 2011-11-17 | Segetis, Inc. | Personal care formulations containing alkyl ketal esters and methods of manufacture |
| CN103536468A (en) * | 2013-10-12 | 2014-01-29 | 广州环亚化妆品科技有限公司 | Traditional Chinese medicine composition with whitening effect and application of traditional Chinese medicine composition in cosmetics |
| CN103932970A (en) * | 2014-04-30 | 2014-07-23 | 温州市姿妃韵化妆品有限公司 | Chinese herbal medicine freckle-removal compound cosmetic and preparation method thereof |
| KR20160055597A (en) * | 2014-11-10 | 2016-05-18 | 이동희 | The composition of functional cosmetics containing silicic acid |
| CN104523490A (en) * | 2014-12-11 | 2015-04-22 | 广州栋方日化有限公司 | Exfoliate composition with whitening and moisturizing effects and preparation method of exfoliate composition |
| CN106852823A (en) * | 2015-12-09 | 2017-06-16 | 张延霞 | A kind of Chinese medicine pox-eliminating whitening facial mask and preparation method thereof |
| CN105769652A (en) * | 2016-03-01 | 2016-07-20 | 苏州艾缇克药物化学有限公司 | Apple facial mask based on traditional Chinese medicine formula |
| KR20170138709A (en) * | 2016-06-08 | 2017-12-18 | 주식회사 코스앤코 | A soap composition for traditional oriental |
| CN107737272A (en) * | 2017-12-03 | 2018-02-27 | 同济大学 | A kind of Chinese medicine composition and its methods for making and using same with freckle removing and whitening effect |
Non-Patent Citations (5)
| Title |
|---|
| LI, KAI等: ""Glycybridins A−K, Bioactive Phenolic Compounds from Glycyrrhiza glabra"", 《JOURNAL OF NATURAL PRODUCTS》 * |
| 余文林等: ""草药与皮肤美白——草药在医学美容方面的应用及未来发展系列讲座二"", 《中国美容医学》 * |
| 尹卫平等: "《精细化工产品及工艺》", 31 August 2009, 华东理工大学出版社 * |
| 裘炳毅等: "《现代化妆品科学与技术：全3册》", 31 March 2016, 中国轻工业出版社 * |
| 齐向东等: "《微创美容外科学》", 28 February 2013, 浙江科学技术出版社 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114209628A (en) * | 2022-01-10 | 2022-03-22 | 山东花物堂生物科技有限公司 | Plant extract composition with whitening effect and application thereof |
| CN115068391A (en) * | 2022-08-05 | 2022-09-20 | 维怡美生物科技(广州)有限公司 | Whitening composition, and whitening essence and whitening lotion containing same |
| CN115068391B (en) * | 2022-08-05 | 2024-01-26 | 维怡美生物科技(广州)有限公司 | Whitening composition, whitening essence containing same and whitening water |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN108403521B (en) | Topical skin compositions and uses thereof | |
| CN101849899B (en) | Chinese medicinal compound extract and cosmetics comprising same as active ingredient | |
| CN112494406A (en) | Whitening and freckle-removing cosmetic and preparation method thereof | |
| CN105381007B (en) | External medicine composition, preparation with white-skinned face function and its preparation method and application | |
| CN108158914A (en) | A kind of Essence of bright color and preparation method thereof | |
| CN109453087B (en) | Whitening skin-penetrating lotion, preparation method thereof and whitening cosmetic additive | |
| CN108210421A (en) | A kind of whitening mask liquid of the extract containing Magnolia binodii and preparation method thereof | |
| CN102406592B (en) | Chinese medicine extract composition with whitening skin care function and application of Chinese medicine extract composition | |
| CN102198079A (en) | Chinese herbal medicine mask | |
| CN103349637B (en) | Compound traditional Chinese medicine extract with effects of whitening and moisturizing, preparation method and application thereof | |
| CN111012725A (en) | Asparagus skin care composition and preparation method thereof | |
| CN103919711A (en) | Oolong anti-aging whitening cream and preparation method thereof | |
| CN109077956A (en) | A kind of face cream and preparation method thereof containing Ganodenna Lucidum P.E | |
| CN109363998A (en) | Skin-lightening cosmetic additive and whitening essence stoste and preparation method thereof | |
| CN109106677A (en) | A kind of composition and its application with whitening function | |
| CN110433122A (en) | A kind of composition and its application in the skin care item for preparing light speckles, beautification and white | |
| CN109846772A (en) | A kind of composition with white-skinned face function, skin care item and preparation method thereof | |
| CN111840201A (en) | Anti-aging and repairing composite preparation containing stem cell factor and preparation method thereof | |
| CN113520966A (en) | Anti-aging long-hair dioscorea opposita essence and preparation method thereof | |
| KR100544024B1 (en) | Skin whitening compound | |
| CN106619278B (en) | A kind of Chinese traditional medicine composition extract with freckle removing and whitening and application | |
| CN113181097A (en) | Acne-removing spot-fading plant compound hydrolat and preparation method and application thereof | |
| CN111700836A (en) | Composition capable of improving skin color and whitening skin and skin care product containing composition | |
| CN105326779B (en) | A kind of whitening curry and preparation method thereof | |
| CN110339127A (en) | A kind of cosmetics and its composition, preparation method and the purposes for improving skin function |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20190607 |