CN105326727A - Wild chrysanthemum flower washing-free hand sanitizer and preparation method thereof - Google Patents

Wild chrysanthemum flower washing-free hand sanitizer and preparation method thereof Download PDF

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Publication number
CN105326727A
CN105326727A CN201510917995.2A CN201510917995A CN105326727A CN 105326727 A CN105326727 A CN 105326727A CN 201510917995 A CN201510917995 A CN 201510917995A CN 105326727 A CN105326727 A CN 105326727A
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CN
China
Prior art keywords
flos chrysanthemi
chrysanthemi indici
preparation
oil
handwashing liquid
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Pending
Application number
CN201510917995.2A
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Chinese (zh)
Inventor
饶雅琴
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Individual
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Individual
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Priority to CN201510917995.2A priority Critical patent/CN105326727A/en
Publication of CN105326727A publication Critical patent/CN105326727A/en
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42Amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations

Abstract

The invention provides wild chrysanthemum flower washing-free hand sanitizer and a preparation method thereof, and relates to the field of daily chemicals. The wild chrysanthemum flower washing-free hand sanitizer is prepared from, by weight, 0.1%-2% of benzalkonium chloride, 0.5%-3% of coco fatty acid diethanol amide, 0.5%-3% of lauramidopropylamine oxide, 5%-10% of glycerin, 1%-5% of olive oil, 3%-10% of vaseline, 1%-5% of vitamin E acetic ester, 1%-5% of hyaluronic acid, 5%-15% of wild chrysanthemum flower extract, 1%-5% of cassie oil and the balance deionized water. The preparation method comprises the steps of preparation of the wild chrysanthemum flower extract, preparation of a water phase, preparation of an oil phase and preparation of the wild chrysanthemum flower washing-free hand sanitizer. The wild chrysanthemum flower washing-free hand sanitizer is good in cleaning effect and moisturizing, small in irritation and suitable for daily use.

Description

Disposable handwashing liquid of a kind of Flos Chrysanthemi Indici and preparation method thereof
Technical field
The present invention relates to a kind of handwashing liquid.
Background technology
Along with the development of society, people are to the attention of Personal hygiene, and handwashing liquid, as the succedaneum of fancy soap, comes into huge numbers of families.Because handwashing liquid is generally bottled, each discharge by pressing uses on a small quantity, and handwashing liquid seldom has secondary pollution problem.But most of handwashing liquid quality comparatively thickness of market, uses afterflush difficulty, uses a large amount of water to be also difficult to rinse well.And the handwashing liquid generally needing water to rush can not use in the absence of water, make troubles can to like this some specific occasion.
Chinese patent application (application number: 201410461023.2) disclose and carry silver-colored mesoporous silicon washing-free antibacterial hand sanitizer and preparation method thereof a kind of containing, the functional components that comprises of the disposable bacteriostatic hand sanitizer of this invention carries silver-colored mesoporous silicon, the life-time service of its heavy metal silver can cause certain injury to skin, and is not suitable for ordinary people's routine use.
Chinese patent application (application number: 201310378336.7) disclose the disposable handwashing liquid of a kind of chitosan Flos Chrysanthemi Indici, chitosan solubilized under slightly acidic condition is utilized to become the gel character easily absorbed, add Sargassum cytokines, the seed of Fructus Crataegi extracting solution with antibacterial action and there is the natural plant composition such as Semen Granati extracting solution of the effect of moistening, forming through special process manufacture.The composition of the disposable handwashing liquid of Flos Chrysanthemi Indici of this invention is made up of natural product extraction substantially, poor to the oils and fats removal ability of hand.
Summary of the invention
For above-mentioned technical problem, the invention provides disposable handwashing liquid of a kind of Flos Chrysanthemi Indici and preparation method thereof.The disposable handwashing liquid of Flos Chrysanthemi Indici of the present invention is made up of the component of following percentage by weight: benzalkonium chloride 0.1 ~ 2%, lauric acid amide of ethanol 0.5 ~ 3%, dodecanamide propyl amine oxide 0.5 ~ 3%, glycerol 5 ~ 10%, olive oil 1 ~ 5%, vaseline 3 ~ 10%, dimension E acetate 1 ~ 5%, hyaluronic acid 1 ~ 5%, Flos Chrysanthemi Indici extracting solution 5 ~ 15%, acacia oil 1 ~ 5%, deionized water surplus.
Further, the disposable handwashing liquid of Flos Chrysanthemi Indici of the present invention is made up of the component of following percentage by weight: benzalkonium chloride 0.5 ~ 1.8%, lauric acid amide of ethanol 0.8 ~ 2%, dodecanamide propyl amine oxide 0.8 ~ 2%, glycerol 6 ~ 9%, olive oil 2 ~ 4%, vaseline 5 ~ 8%, dimension E acetate 2 ~ 4%, hyaluronic acid 2 ~ 4%, Flos Chrysanthemi Indici extracting solution 8 ~ 13%, acacia oil 2 ~ 4%, deionized water surplus.
Particularly, the disposable handwashing liquid of Flos Chrysanthemi Indici of the present invention is made up of the component of following percentage by weight: benzalkonium chloride 1%, lauric acid amide of ethanol 1%, dodecanamide propyl amine oxide 1%, glycerol 8%, olive oil 3%, vaseline 6%, dimension E acetate 3%, hyaluronic acid 3%, Flos Chrysanthemi Indici extracting solution 10%, acacia oil 3%, deionized water surplus.
The preparation method of the disposable handwashing liquid of Flos Chrysanthemi Indici of the present invention comprises the following steps:
(1). the preparation of aqueous phase: by formula ratio, after hyaluronic acid and benzalkonium chloride deionized water solution, adds Flos Chrysanthemi Indici extracting solution, mix homogeneously, is heated to 60 ~ 70 DEG C;
(2). the preparation of oil phase: by formula ratio, is uniformly mixed lauric acid amide of ethanol, dodecanamide propyl amine oxide, glycerol, olive oil, vaseline 5 ~ 8%, dimension E acetate and acacia oil, is heated to 50 ~ 60 DEG C;
(3). the preparation of the disposable handwashing liquid of Flos Chrysanthemi Indici: keep aqueous phase temperature, under stirring, the oil phase that step (2) is obtained is added in the obtained aqueous phase of step (1), make its emulsifying, slow cooling after emulsifying, add excess water, continue to be stirred to and be cooled to room temperature.
Wherein, the preparation method of described Flos Chrysanthemi Indici extracting solution is as follows: Flos Chrysanthemi Indici is crushed to by 200 mesh sieves after cleaning, and adds the ratio of 3g water, be added to the water by Flos Chrysanthemi Indici powder in 1g Flos Chrysanthemi Indici powder, reflux 3 ~ 5 hours, gained suspension cools rear elimination insoluble matter and get final product.
Flos Chrysanthemi Indici of the present invention disposable handwashing liquid viscosity is less, adopts cationic surfactant to kill various bacteria.Product of the present invention is not containing ethanol, and therefore zest is weak, is suitable for crowd wide.Acacia oil coordinates Flos Chrysanthemi Indici extract, hyaluronic acid and olive oil to have the effect of extraordinary moisturizing, and abnormal smells from the patient is pure and fresh, while clean both hands, also can provide good protection to hand skin.
In order to understand better and implement, the following detailed description of the present invention.
Detailed description of the invention
preparation embodiment
The disposable handwashing liquid of Flos Chrysanthemi Indici of the present invention is prepared by following steps:
(1). the preparation of Flos Chrysanthemi Indici extract: Flos Chrysanthemi Indici is crushed to by 200 mesh sieves after cleaning, and adds the ratio of 3g water, is added to the water by Flos Chrysanthemi Indici powder, reflux 3 ~ 5 hours in 1g Flos Chrysanthemi Indici powder, gained suspension cools rear elimination insoluble matter and get final product.
(2). the preparation of aqueous phase: by table 1 formula ratio, after hyaluronic acid and benzalkonium chloride deionized water solution, adds Flos Chrysanthemi Indici extracting solution, mix homogeneously, is heated to 60 ~ 70 DEG C;
(3). the preparation of oil phase: by table 1 formula ratio, is uniformly mixed lauric acid amide of ethanol, dodecanamide propyl amine oxide, glycerol, olive oil, vaseline 5 ~ 8%, dimension E acetate and acacia oil, is heated to 50 ~ 60 DEG C;
(4). the preparation of the disposable handwashing liquid of Flos Chrysanthemi Indici: keep aqueous phase temperature, under stirring, the oil phase that step (2) is obtained is added in the obtained aqueous phase of step (1), make its emulsifying, slow cooling after emulsifying, add excess water, continue to be stirred to and be cooled to room temperature.
The each component formula amount of < table 1 is in percentage by weight (%) >
effect example
Effect of above-described embodiment 1-5 is described respectively by sensory evaluation below.
60 testers are equally divided into 6 groups, test group sample is given at random by " double blinding " test, require that tester to wash one's hands (i.e. handwashing liquid consumption by self daily custom of washing one's hands, Handwashing ways does not limit), cleaning effect, moist type and zest when the disposable handwashing liquid of the Flos Chrysanthemi Indici successively obtained by Evaluation operation example 1 ~ 5 is washed one's hands.
Tester according to oneself feel mark, standards of grading adopt 5 points of systems, the poorest with 1 point, and 5 points preferably calculate, finally with the sensory effects of mean values record each embodiment scoring, as shown in table 2 below.
< shows 2>
Embodiment 1 Embodiment 2 Embodiment 3 Embodiment 4 Embodiment 5 Comparative example
Cleaning effect 4.9 4.7 4.7 4.6 4.7 3.0
Moistness 4.6 4.9 4.7 4.7 4.5 3.1
Moisture retention 4.9 4.6 4.5 4.9 4.9 3.3
Zest 1.2 1.3 1.3 1.2 1.1 1.8
Can be drawn by upper table, the cleaning effect of the disposable handwashing liquid of the Flos Chrysanthemi Indici that the present embodiment obtains and moisturizing are all fine, and zest is very little, and tester is good with rear reflection.
The present invention is not limited to above-mentioned embodiment, if do not depart from the spirit and scope of the present invention to various change of the present invention or distortion, if these are changed and distortion belongs within claim of the present invention and equivalent technologies scope, then the present invention is also intended to comprise these changes and distortion.

Claims (5)

1. the disposable handwashing liquid of Flos Chrysanthemi Indici, is characterized in that being made up of the component of following percentage by weight: benzalkonium chloride 0.1 ~ 2%, lauric acid amide of ethanol 0.5 ~ 3%, dodecanamide propyl amine oxide 0.5 ~ 3%, glycerol 5 ~ 10%, olive oil 1 ~ 5%, vaseline 3 ~ 10%, dimension E acetate 1 ~ 5%, hyaluronic acid 1 ~ 5%, Flos Chrysanthemi Indici extracting solution 5 ~ 15%, acacia oil 1 ~ 5%, deionized water surplus.
2. the disposable handwashing liquid of Flos Chrysanthemi Indici according to claim 1, is characterized in that being made up of the component of following percentage by weight: benzalkonium chloride 0.5 ~ 1.8%, lauric acid amide of ethanol 0.8 ~ 2%, dodecanamide propyl amine oxide 0.8 ~ 2%, glycerol 6 ~ 9%, olive oil 2 ~ 4%, vaseline 5 ~ 8%, dimension E acetate 2 ~ 4%, hyaluronic acid 2 ~ 4%, Flos Chrysanthemi Indici extracting solution 8 ~ 13%, acacia oil 2 ~ 4%, deionized water surplus.
3. the disposable handwashing liquid of Flos Chrysanthemi Indici according to claim 2, is characterized in that being made up of the component of following percentage by weight: benzalkonium chloride 1%, lauric acid amide of ethanol 1%, dodecanamide propyl amine oxide 1%, glycerol 8%, olive oil 3%, vaseline 6%, dimension E acetate 3%, hyaluronic acid 3%, Flos Chrysanthemi Indici extracting solution 10%, acacia oil 3%, deionized water surplus.
4. prepare the method for the disposable handwashing liquid of Flos Chrysanthemi Indici described in claims 1 to 3 any one, it is characterized in that comprising the following steps:
(1). the preparation of aqueous phase: by formula ratio, after hyaluronic acid and benzalkonium chloride deionized water solution, adds Flos Chrysanthemi Indici extracting solution, mix homogeneously, is heated to 60 ~ 70 DEG C;
(2). the preparation of oil phase: by formula ratio, is uniformly mixed lauric acid amide of ethanol, dodecanamide propyl amine oxide, glycerol, olive oil, vaseline 5 ~ 8%, dimension E acetate and acacia oil, is heated to 50 ~ 60 DEG C;
(3). the preparation of the disposable handwashing liquid of Flos Chrysanthemi Indici: keep aqueous phase temperature, under stirring, the oil phase that step (2) is obtained is added in the obtained aqueous phase of step (1), make its emulsifying, slow cooling after emulsifying, add excess water, continue to be stirred to and be cooled to room temperature.
5. the disposable handwashing liquid of Flos Chrysanthemi Indici according to claim 4, it is characterized in that the preparation method of described Flos Chrysanthemi Indici extracting solution is as follows: Flos Chrysanthemi Indici is crushed to by 200 mesh sieves after cleaning, the ratio of 3g water is added in 1g Flos Chrysanthemi Indici powder, Flos Chrysanthemi Indici powder is added to the water, reflux 3 ~ 5 hours, gained suspension cools rear elimination insoluble matter and get final product.
CN201510917995.2A 2015-12-11 2015-12-11 Wild chrysanthemum flower washing-free hand sanitizer and preparation method thereof Pending CN105326727A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510917995.2A CN105326727A (en) 2015-12-11 2015-12-11 Wild chrysanthemum flower washing-free hand sanitizer and preparation method thereof

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Application Number Priority Date Filing Date Title
CN201510917995.2A CN105326727A (en) 2015-12-11 2015-12-11 Wild chrysanthemum flower washing-free hand sanitizer and preparation method thereof

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109172444A (en) * 2018-09-26 2019-01-11 明辉实业(深圳)有限公司 A kind of leave hand cleanser and preparation method thereof
CN109833216A (en) * 2017-11-24 2019-06-04 马文娅 A kind of disposable hand sanitizer formula
CN115737706A (en) * 2022-11-23 2023-03-07 海南皇隆制药股份有限公司 Benzalkonium chloride solution and preparation method thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101684435A (en) * 2008-09-28 2010-03-31 福建恒安集团有限公司 Sterilization hand washing solution
CN101766552A (en) * 2010-01-20 2010-07-07 华南理工大学 Washing-free antibacterial hand sanitizer and preparation method thereof
CN104173250A (en) * 2014-09-12 2014-12-03 皖南医学院 Skin-nourishing liquid soap containing natural bacteriostatic components and preparation method thereof
CN104188811A (en) * 2014-07-30 2014-12-10 广州立白企业集团有限公司 Foam type wash-free antibacterial liquid soap and using method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101684435A (en) * 2008-09-28 2010-03-31 福建恒安集团有限公司 Sterilization hand washing solution
CN101766552A (en) * 2010-01-20 2010-07-07 华南理工大学 Washing-free antibacterial hand sanitizer and preparation method thereof
CN104188811A (en) * 2014-07-30 2014-12-10 广州立白企业集团有限公司 Foam type wash-free antibacterial liquid soap and using method thereof
CN104173250A (en) * 2014-09-12 2014-12-03 皖南医学院 Skin-nourishing liquid soap containing natural bacteriostatic components and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
国家食品药品监督管理总局: "《化妆品安全技术规范》", 23 December 2015 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109833216A (en) * 2017-11-24 2019-06-04 马文娅 A kind of disposable hand sanitizer formula
CN109172444A (en) * 2018-09-26 2019-01-11 明辉实业(深圳)有限公司 A kind of leave hand cleanser and preparation method thereof
CN115737706A (en) * 2022-11-23 2023-03-07 海南皇隆制药股份有限公司 Benzalkonium chloride solution and preparation method thereof
CN115737706B (en) * 2022-11-23 2023-08-29 海南皇隆制药股份有限公司 Benzalkonium chloride solution and preparation method thereof

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Application publication date: 20160217

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