CN105307634B - 含有改性瓜尔胶的药物软明胶胶囊剂型 - Google Patents

含有改性瓜尔胶的药物软明胶胶囊剂型 Download PDF

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Publication number
CN105307634B
CN105307634B CN201480022804.XA CN201480022804A CN105307634B CN 105307634 B CN105307634 B CN 105307634B CN 201480022804 A CN201480022804 A CN 201480022804A CN 105307634 B CN105307634 B CN 105307634B
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CN
China
Prior art keywords
dosage form
soft gelatin
gelatin capsule
capsule dosage
pharmaceutical soft
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201480022804.XA
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English (en)
Chinese (zh)
Other versions
CN105307634A (zh
Inventor
B·穆尔顿
R·G·洛夫林
G·斯威尼
E·K·博伊德
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alegen Treatment Co ltd
Allergan Pharmaceuticals Holdings Ireland ULC
Original Assignee
Warner Chilcott Co LLC
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Filing date
Publication date
Application filed by Warner Chilcott Co LLC filed Critical Warner Chilcott Co LLC
Priority to CN202010063854.XA priority Critical patent/CN111374959A/zh
Publication of CN105307634A publication Critical patent/CN105307634A/zh
Application granted granted Critical
Publication of CN105307634B publication Critical patent/CN105307634B/zh
Expired - Fee Related legal-status Critical Current
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A61K9/4825—Proteins, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201480022804.XA 2013-03-15 2014-03-14 含有改性瓜尔胶的药物软明胶胶囊剂型 Expired - Fee Related CN105307634B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202010063854.XA CN111374959A (zh) 2013-03-15 2014-03-14 含有改性瓜尔胶的药物软明胶胶囊剂型

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361794906P 2013-03-15 2013-03-15
US61/794,906 2013-03-15
PCT/US2014/027145 WO2014152269A1 (en) 2013-03-15 2014-03-14 Pharmaceutical soft gelatin capsule dosage form with modified guar gum

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN202010063854.XA Division CN111374959A (zh) 2013-03-15 2014-03-14 含有改性瓜尔胶的药物软明胶胶囊剂型

Publications (2)

Publication Number Publication Date
CN105307634A CN105307634A (zh) 2016-02-03
CN105307634B true CN105307634B (zh) 2020-03-10

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ID=50588879

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201480022804.XA Expired - Fee Related CN105307634B (zh) 2013-03-15 2014-03-14 含有改性瓜尔胶的药物软明胶胶囊剂型
CN202010063854.XA Pending CN111374959A (zh) 2013-03-15 2014-03-14 含有改性瓜尔胶的药物软明胶胶囊剂型

Family Applications After (1)

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CN202010063854.XA Pending CN111374959A (zh) 2013-03-15 2014-03-14 含有改性瓜尔胶的药物软明胶胶囊剂型

Country Status (14)

Country Link
US (3) US9795569B2 (https=)
EP (2) EP3187170A1 (https=)
JP (3) JP6335270B2 (https=)
KR (1) KR20150131070A (https=)
CN (2) CN105307634B (https=)
AU (2) AU2014239994B2 (https=)
BR (1) BR112015022946A8 (https=)
CA (1) CA2906633C (https=)
ES (1) ES2619121T3 (https=)
HK (1) HK1218622A1 (https=)
IL (1) IL241377B (https=)
MX (2) MX364440B (https=)
RU (1) RU2676480C2 (https=)
WO (1) WO2014152269A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2906633C (en) * 2013-03-15 2021-11-30 Warner Chilcott Company, Llc Pharmaceutical soft gelatin capsule dosage form with modified guar gum
ES2787220T3 (es) 2015-03-26 2020-10-15 Patheon Softgels Inc Cápsulas blandas llenas de líquido
JP2017214299A (ja) * 2016-05-30 2017-12-07 ライオン株式会社 半固形製剤及びその製造方法
CN116916895A (zh) * 2020-11-13 2023-10-20 辉瑞公司 他拉唑帕尼软明胶胶囊剂型
CA3201467A1 (en) * 2020-11-13 2022-05-19 Pfizer Inc. Talazoparib soft gelatin capsule dosage form
CN116531444B (zh) * 2023-07-06 2023-10-10 健码制药（广东）有限公司 镇咳清肺软胶囊及其制备工艺

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CN1198665A (zh) * 1995-10-05 1998-11-11 伊诺托拉实验室 用于阴道干燥的局部激素疗法的单位盖仑制剂
US5945398A (en) * 1997-09-08 1999-08-31 Panacea Biotec Limited Pharmaceutical compositions containing cyclosporin
EP1527169A2 (fr) * 2002-08-07 2005-05-04 Ricarimpex Extraits de sangsues pour stents
CN101360485A (zh) * 2005-10-26 2009-02-04 班纳制药公司 作为胶囊填充物的基于亲水性载体的双重控释基质系统

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WO1997033568A1 (en) 1996-03-12 1997-09-18 Novartis Ag Filled gelatin capsules having a reduced degree of cross-linking
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US6187747B1 (en) * 1997-09-08 2001-02-13 Panacea Biotech Limited Pharmaceutical composition comprising cyclosporin
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US6251426B1 (en) * 1999-09-02 2001-06-26 Banner Pharmacaps, Inc. Ibuprofen-containing softgels
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US20050142185A1 (en) * 2003-12-29 2005-06-30 Beleno Alfredo B. Softgel formulations of bisphosphonates bone resorption inhibitors
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Publication number Priority date Publication date Assignee Title
CN1198665A (zh) * 1995-10-05 1998-11-11 伊诺托拉实验室 用于阴道干燥的局部激素疗法的单位盖仑制剂
EP0770384A1 (en) * 1995-10-27 1997-05-02 Montefarmaco S.p.A. Solid, anhydrous, pharmaceutical compositions for vaginal use
US5945398A (en) * 1997-09-08 1999-08-31 Panacea Biotec Limited Pharmaceutical compositions containing cyclosporin
EP1527169A2 (fr) * 2002-08-07 2005-05-04 Ricarimpex Extraits de sangsues pour stents
CN101360485A (zh) * 2005-10-26 2009-02-04 班纳制药公司 作为胶囊填充物的基于亲水性载体的双重控释基质系统

Also Published As

Publication number Publication date
ES2619121T3 (es) 2017-06-23
JP6704430B2 (ja) 2020-06-03
KR20150131070A (ko) 2015-11-24
US10744096B2 (en) 2020-08-18
JP2018140998A (ja) 2018-09-13
US20180036252A1 (en) 2018-02-08
CN105307634A (zh) 2016-02-03
MX2019004554A (es) 2019-08-05
AU2014239994A1 (en) 2015-10-08
IL241377A0 (en) 2015-11-30
EP2950781B1 (en) 2016-12-21
WO2014152269A1 (en) 2014-09-25
US20150044285A1 (en) 2015-02-12
CA2906633A1 (en) 2014-09-25
MX2015012057A (es) 2016-05-05
AU2014239994B2 (en) 2019-01-24
JP2020147569A (ja) 2020-09-17
US9820946B2 (en) 2017-11-21
EP3187170A1 (en) 2017-07-05
JP2016513684A (ja) 2016-05-16
EP2950781A1 (en) 2015-12-09
IL241377B (en) 2019-08-29
BR112015022946A2 (pt) 2017-07-18
US9795569B2 (en) 2017-10-24
CA2906633C (en) 2021-11-30
NZ712280A (en) 2021-01-29
MX364440B (es) 2019-04-26
AU2019200116A1 (en) 2019-01-31
BR112015022946A8 (pt) 2022-11-29
CN111374959A (zh) 2020-07-07
JP6335270B2 (ja) 2018-05-30
HK1218622A1 (zh) 2017-03-03
RU2015137612A (ru) 2017-04-24
US20140271838A1 (en) 2014-09-18
RU2676480C2 (ru) 2018-12-29

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C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
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GR01 Patent grant
TR01 Transfer of patent right
TR01 Transfer of patent right

Effective date of registration: 20211227

Address after: New Jersey USA

Patentee after: Alegen treatment Co.,Ltd.

Address before: Irish Dublin

Patentee before: APTALIS PHARMA LTD.

Effective date of registration: 20211227

Address after: Irish Dublin

Patentee after: APTALIS PHARMA LTD.

Address before: Puerto Rico

Patentee before: WARNER CHILCOTT Co.,LLC

CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20200310