CN105232429A - Antiallergic gingival protecting toothpaste with high-stability traditional Chinese medicine small molecule compounds added and preparation method - Google Patents

Antiallergic gingival protecting toothpaste with high-stability traditional Chinese medicine small molecule compounds added and preparation method Download PDF

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Publication number
CN105232429A
CN105232429A CN201510768743.8A CN201510768743A CN105232429A CN 105232429 A CN105232429 A CN 105232429A CN 201510768743 A CN201510768743 A CN 201510768743A CN 105232429 A CN105232429 A CN 105232429A
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powder
traditional chinese
toothpaste
antiallergic
alkalescence
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周蓼蓼
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Zhejiang Industry and Trade Vocational College
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Zhejiang Industry and Trade Vocational College
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines

Abstract

The invention discloses antiallergic gingival protecting toothpaste with high-stability traditional Chinese medicine small molecule compounds added and a preparation method. The antiallergic gingival protecting toothpaste is prepared from cuttlebone powder, soluble chitosan oligosaccharide, aspartame, radix zanthoxyli extracts, aloe gel, menthol, natural betaine, lavender essential oil, natural coconut juice powder, osmanthus powder, spirulina powder, lecithin, sorbitol-based green dispersion liquid, protein-based surface active agent sodium caseinate, tourmaline nanometer powder, glycerinum, sodium benzoate and other raw materials. The acting force and permeability of Chinese herbal medicine ingredients are improved through nanometer small molecularization, and the acting effect of the toothpaste within the short period of time is improved; meanwhile, through the decoration treatment of soluble chitosan, and the stability of small molecular Chinese herbal medicine ingredients of the toothpaste is improved; meanwhile, protein-based surface active agent sodium caseinate and cuttlebone powder serve as abrasives, radix zanthoxyli and aloe gel are importantly adopted, and therefore the cleaning function, the acid resistance function, the antiallergic function and other gingival protecting functions can be achieved.

Description

A kind of antiallergic of adding high stable Traditional Chinese Herb complex protects gum toothpaste and preparation method
Technical field
The invention belongs to functional type Chinese herbal toothpaste field, specifically relate to a kind of antiallergic of adding high stable Traditional Chinese Herb complex and protect gum toothpaste and preparation method.
Background technology
Current toothpaste is of a great variety, medicated toothpaste adds certain medicine on the basis of ordinary toothpaste, by the effect of medicine, reduce dental plaque, thus play the effect of anti-dental caries and periodontal disease, at present, medicated toothpaste pole is by the favor of people, and utilize toothpaste to promote the medicine with prevention effects and therapeutic efficiency to be a kind of comparatively ideal mode, but medicated toothpaste also has unfavorable aspect, first, toothpaste can not retain the long time and namely be gargled in mouth, medicine is made to be difficult to play drug effect at short notice, and special medicament dosage also must be avoided stimulating soft tissue in mouth, thus enough valid density can not be brought up to, the effect of toothpaste itself often hinder by dirt in mouth or limit by morphological characteristic, thus the region arriving real morbidity is difficult to, secondly the medicine in toothpaste, because standing time longer two, other chemical change occurred, lose original drug effect, active drug again Chang Yin is unsuitable for abnormal flavour and puts into toothpaste.Medicated toothpaste is a kind of imagination well, but the effect that really will reach prevention oral pathology needs to do some deep researchs.
Summary of the invention
For solving the problems of the technologies described above, the invention provides a kind of antiallergic of adding high stable Traditional Chinese Herb complex and protecting gum toothpaste and preparation method.
For achieving the above object, the technical solution used in the present invention is:
A kind of antiallergic of adding high stable Traditional Chinese Herb complex protects gum toothpaste, comprise by the raw material of following weight portion: Endoconcha Sepiae powder 25-35, solubility oligochitosan 1.6-2, aspartame 0.9-1.5, Radix Zanthoxyli extract 1-2, aloe gel 1:1-2, menthol 0.9-1.7, natural betanin 0.3-0.9, Herba Lysimachiae foenum-graeci quintessence oil 0.2-0.4, natural coconut juice powder 1.1-1.3, pollen powder of sweet osmanthus 1.2-1.4, Spirulina powder 1-1.2, lecithin 0.9-1, the green dispersion liquid 0.2-0.3 of Pyrusussuriensis alcohol radical, protein-based surfactant sodium caseinate 1.3-1.7, tourmaline nanometer powder 4-6, glycerol 2-3, sodium benzoate 0.2-0.4, guar gum 0.2-0.3, appropriate alkalescence subset activated water.
The antiallergic of adding high stable Traditional Chinese Herb complex protects a preparation method for gum toothpaste, comprises the following steps:
(1) Radix Zanthoxyli extract, Aloe gel, menthol, natural betanin, Herba Lysimachiae foenum-graeci quintessence oil mixing is got, and the alkalescence subset activated water adding gross weight 3-4 times stirs, put into nanometer generator nanometered disposal 2-3h afterwards, obtain Traditional Chinese Herb complex for subsequent use;
(2) by Traditional Chinese Herb complex, the mixing of solubility oligochitosan, and add gross weight 3-4 alkalescence subset activated water doubly, adopt high pressure homogenizer homogenizing process 2-2.4h afterwards, employing spray drying technology is dry that high stable Traditional Chinese Herb is for subsequent use;
(3) by Endoconcha Sepiae powder, tourmaline nanometer powder mixing, gross weight 1-1.2 alkalescence subset activated water is doubly added, after stirring, heated and stirred 3h at 180 DEG C, cooling ball milling, crosses 120 orders, obtains activated substrate composite powder for subsequent use;
(4) by natural coconut juice powder, pollen powder of sweet osmanthus, Spirulina powder, lecithin mixing, and add gross weight 2-3 alkalescence subset activated water doubly, at 100 DEG C, heated and stirred 40-60min is to even ripening, and cooling, obtains complex liquid for subsequent use;
(5) by activated substrate composite powder, high stable Traditional Chinese Herb, complex liquid, the green dispersion liquid of Pyrusussuriensis alcohol radical, aspartame, the blender of band magnetic stirring apparatus is put in glycerol mixing, and add gross weight 3-4 alkalescence subset activated water doubly, open magnetic stirring apparatus high-speed stirred 1.2-1.6h, add protein-based surfactant sodium caseinate afterwards, and continue slowly to be stirred to evenly, adding sodium benzoate afterwards, magnetic stirring apparatus is first adopted to strengthen magnetic force rapid stirring 1-2h, slowly adding guar gum, and continue stirring until evenly, high pressure is finally adopted to assist degassed process 4-5h to form uniform and stable body of paste, adopt Sterile vacuum tinning technology, tinning seals and get final product.
Beneficial effect of the present invention:
The present invention is directed to the problem of the Chinese herbal medicine inefficacy caused through processing and long-time shelf life of Chinese herbal toothpaste and toothpaste retention time in human mouth short drug effect caused defect that cannot give full play to and deficiency, propose and medicinal herb components is improved its active force and permeability by nano micromolecule, improve the action effect in its short time, simultaneously, by the moditied processing of solubility oligochitosan, improve the stability of its micromolecule medicinal herb components, solve Chinese herbal toothpaste problems faced, simultaneously, by adopting white matter based surfactants sodium caseinate, adopt Endoconcha Sepiae powder as abrasivus and Radix Zanthoxyli and Aloe gel important, can effectively play clean and antiacid, antiallergic etc. protect gum effect.
Detailed description of the invention
Below in conjunction with specific embodiment, technical scheme of the present invention is further described.
Embodiment 1:
A kind of antiallergic of adding high stable Traditional Chinese Herb complex protects gum toothpaste, comprise by the raw material of following weight (kg): Endoconcha Sepiae powder 25, solubility oligochitosan 1.6, aspartame 0.9, Radix Zanthoxyli extract 1, aloe gel 1:1, menthol 0.9, natural betanin 0.3, Herba Lysimachiae foenum-graeci quintessence oil 0.2, natural coconut juice powder 1.3, pollen powder of sweet osmanthus 1.4, Spirulina powder 1.2, lecithin 1, the green dispersion liquid 0.25 of Pyrusussuriensis alcohol radical, protein-based surfactant sodium caseinate 1.5, tourmaline nanometer powder 4, glycerol 2.5, sodium benzoate 0.3, guar gum 0.25, appropriate alkalescence subset activated water.
The antiallergic of adding high stable Traditional Chinese Herb complex protects a preparation method for gum toothpaste, comprises the following steps:
(1) Radix Zanthoxyli extract, Aloe gel, menthol, natural betanin, Herba Lysimachiae foenum-graeci quintessence oil mixing is got, and the alkalescence subset activated water adding gross weight 3 times stirs, put into nanometer generator nanometered disposal 2h afterwards, obtain Traditional Chinese Herb complex for subsequent use;
(2) by Traditional Chinese Herb complex, the mixing of solubility oligochitosan, and add the alkalescence subset activated water of gross weight 3 times, adopt high pressure homogenizer homogenizing process 2h afterwards, employing spray drying technology is dry that high stable Traditional Chinese Herb is for subsequent use;
(3) by Endoconcha Sepiae powder, tourmaline nanometer powder mixing, the alkalescence subset activated water of gross weight 1 times is added, after stirring, heated and stirred 3h at 180 DEG C, cooling ball milling, crosses 120 orders, obtains activated substrate composite powder for subsequent use;
(4) by natural coconut juice powder, pollen powder of sweet osmanthus, Spirulina powder, lecithin mixing, and add the alkalescence subset activated water of gross weight 2 times, at 100 DEG C, heated and stirred 40min is to even ripening, and cooling, obtains complex liquid for subsequent use;
(5) by activated substrate composite powder, high stable Traditional Chinese Herb, complex liquid, the green dispersion liquid of Pyrusussuriensis alcohol radical, aspartame, the blender of band magnetic stirring apparatus is put in glycerol mixing, and add the alkalescence subset activated water of gross weight 3 times, open magnetic stirring apparatus high-speed stirred 1.2h, add protein-based surfactant sodium caseinate afterwards, and continue slowly to be stirred to evenly, adding sodium benzoate afterwards, magnetic stirring apparatus is first adopted to strengthen magnetic force rapid stirring 1h, slowly adding guar gum, and continue stirring until evenly, high pressure is finally adopted to assist degassed process 4h to form uniform and stable body of paste, adopt Sterile vacuum tinning technology, tinning seals and get final product.
Embodiment 2:
A kind of antiallergic of adding high stable Traditional Chinese Herb complex protects gum toothpaste, comprise by the raw material of following weight (kg): Endoconcha Sepiae powder 30, solubility oligochitosan 1.9, aspartame 1.2, Radix Zanthoxyli extract 1.5, aloe gel 1:1 .5, menthol 1.3, natural betanin 0.6, Herba Lysimachiae foenum-graeci quintessence oil 0.3, natural coconut juice powder 1.2, pollen powder of sweet osmanthus 1.3, Spirulina powder 1.1, lecithin 0.9, the green dispersion liquid 0.25 of Pyrusussuriensis alcohol radical, protein-based surfactant sodium caseinate 1.5, tourmaline nanometer powder 5, glycerol 2.5, sodium benzoate 0.3, guar gum 0.25, appropriate alkalescence subset activated water.
The antiallergic of adding high stable Traditional Chinese Herb complex protects a preparation method for gum toothpaste, comprises the following steps:
(1) Radix Zanthoxyli extract, Aloe gel, menthol, natural betanin, Herba Lysimachiae foenum-graeci quintessence oil mixing is got, and the alkalescence subset activated water adding gross weight 3.5 times stirs, put into nanometer generator nanometered disposal 2.5h afterwards, obtain Traditional Chinese Herb complex for subsequent use;
(2) by Traditional Chinese Herb complex, the mixing of solubility oligochitosan, and add the alkalescence subset activated water of gross weight 3.5 times, adopt high pressure homogenizer homogenizing process 2.2h afterwards, employing spray drying technology is dry that high stable Traditional Chinese Herb is for subsequent use;
(3) by Endoconcha Sepiae powder, tourmaline nanometer powder mixing, the alkalescence subset activated water of gross weight 1.1 times is added, after stirring, heated and stirred 3h at 180 DEG C, cooling ball milling, crosses 120 orders, obtains activated substrate composite powder for subsequent use;
(4) by natural coconut juice powder, pollen powder of sweet osmanthus, Spirulina powder, lecithin mixing, and add the alkalescence subset activated water of gross weight 2.5 times, at 100 DEG C, heated and stirred 50min is to even ripening, and cooling, obtains complex liquid for subsequent use;
(5) by activated substrate composite powder, high stable Traditional Chinese Herb, complex liquid, the green dispersion liquid of Pyrusussuriensis alcohol radical, aspartame, the blender of band magnetic stirring apparatus is put in glycerol mixing, and add the alkalescence subset activated water of gross weight 3.5 times, open magnetic stirring apparatus high-speed stirred 1.4h, add protein-based surfactant sodium caseinate afterwards, and continue slowly to be stirred to evenly, adding sodium benzoate afterwards, magnetic stirring apparatus is first adopted to strengthen magnetic force rapid stirring 1.5h, slowly adding guar gum, and continue stirring until evenly, high pressure is finally adopted to assist degassed process 4.5h to form uniform and stable body of paste, adopt Sterile vacuum tinning technology, tinning seals and get final product.
Embodiment 3:
A kind of antiallergic of adding high stable Traditional Chinese Herb complex protects gum toothpaste, comprise by the raw material of following weight (kg): Endoconcha Sepiae powder 35, solubility oligochitosan 2, aspartame 1.5, Radix Zanthoxyli extract 2, Aloe gel 2, menthol 1.7, natural betanin 0.9, Herba Lysimachiae foenum-graeci quintessence oil 0.4, natural coconut juice powder 1.1, pollen powder of sweet osmanthus 1.2, Spirulina powder 1, lecithin 0.9, the green dispersion liquid 0.25 of Pyrusussuriensis alcohol radical, protein-based surfactant sodium caseinate 1.5, tourmaline nanometer powder 6, glycerol 3, sodium benzoate 0.3, guar gum 0.25, appropriate alkalescence subset activated water.
The antiallergic of adding high stable Traditional Chinese Herb complex protects a preparation method for gum toothpaste, comprises the following steps:
(1) Radix Zanthoxyli extract, Aloe gel, menthol, natural betanin, Herba Lysimachiae foenum-graeci quintessence oil mixing is got, and the alkalescence subset activated water adding gross weight 4 times stirs, put into nanometer generator nanometered disposal 3h afterwards, obtain Traditional Chinese Herb complex for subsequent use;
(2) by Traditional Chinese Herb complex, the mixing of solubility oligochitosan, and add the alkalescence subset activated water of gross weight 4 times, adopt high pressure homogenizer homogenizing process 2.4h afterwards, employing spray drying technology is dry that high stable Traditional Chinese Herb is for subsequent use;
(3) by Endoconcha Sepiae powder, tourmaline nanometer powder mixing, the alkalescence subset activated water of gross weight 1.2 times is added, after stirring, heated and stirred 3h at 180 DEG C, cooling ball milling, crosses 120 orders, obtains activated substrate composite powder for subsequent use;
(4) by natural coconut juice powder, pollen powder of sweet osmanthus, Spirulina powder, lecithin mixing, and add the alkalescence subset activated water of gross weight 3 times, at 100 DEG C, heated and stirred 60min is to even ripening, and cooling, obtains complex liquid for subsequent use;
(5) by activated substrate composite powder, high stable Traditional Chinese Herb, complex liquid, the green dispersion liquid of Pyrusussuriensis alcohol radical, aspartame, the blender of band magnetic stirring apparatus is put in glycerol mixing, and add the alkalescence subset activated water of gross weight 4 times, open magnetic stirring apparatus high-speed stirred 1.6h, add protein-based surfactant sodium caseinate afterwards, and continue slowly to be stirred to evenly, adding sodium benzoate afterwards, magnetic stirring apparatus is first adopted to strengthen magnetic force rapid stirring 2h, slowly adding guar gum, and continue stirring until evenly, high pressure is finally adopted to assist degassed process 5h to form uniform and stable body of paste, adopt Sterile vacuum tinning technology, tinning seals and get final product.

Claims (2)

1. an antiallergic of adding high stable Traditional Chinese Herb complex protects gum toothpaste, it is characterized in that, comprise by the raw material of following weight portion: Endoconcha Sepiae powder 25-35, solubility oligochitosan 1.6-2, aspartame 0.9-1.5, Radix Zanthoxyli extract 1-2, aloe gel 1:1-2, menthol 0.9-1.7, natural betanin 0.3-0.9, Herba Lysimachiae foenum-graeci quintessence oil 0.2-0.4, natural coconut juice powder 1.1-1.3, pollen powder of sweet osmanthus 1.2-1.4, Spirulina powder 1-1.2, lecithin 0.9-1, the green dispersion liquid 0.2-0.3 of Pyrusussuriensis alcohol radical, protein-based surfactant sodium caseinate 1.3-1.7, tourmaline nanometer powder 4-6, glycerol 2-3, sodium benzoate 0.2-0.4, guar gum 0.2-0.3, appropriate alkalescence subset activated water.
2. antiallergic of adding high stable Traditional Chinese Herb complex as claimed in claim 1 protects a preparation method for gum toothpaste, it is characterized in that, comprises the following steps:
(1) Radix Zanthoxyli extract, Aloe gel, menthol, natural betanin, Herba Lysimachiae foenum-graeci quintessence oil mixing is got, and the alkalescence subset activated water adding gross weight 3-4 times stirs, put into nanometer generator nanometered disposal 2-3h afterwards, obtain Traditional Chinese Herb complex for subsequent use;
(2) by Traditional Chinese Herb complex, the mixing of solubility oligochitosan, and add gross weight 3-4 alkalescence subset activated water doubly, adopt high pressure homogenizer homogenizing process 2-2.4h afterwards, employing spray drying technology is dry that high stable Traditional Chinese Herb is for subsequent use;
(3) by Endoconcha Sepiae powder, tourmaline nanometer powder mixing, gross weight 1-1.2 alkalescence subset activated water is doubly added, after stirring, heated and stirred 3h at 180 DEG C, cooling ball milling, crosses 120 orders, obtains activated substrate composite powder for subsequent use;
(4) by natural coconut juice powder, pollen powder of sweet osmanthus, Spirulina powder, lecithin mixing, and add gross weight 2-3 alkalescence subset activated water doubly, at 100 DEG C, heated and stirred 40-60min is to even ripening, and cooling, obtains complex liquid for subsequent use;
(5) by activated substrate composite powder, high stable Traditional Chinese Herb, complex liquid, the green dispersion liquid of Pyrusussuriensis alcohol radical, aspartame, the blender of band magnetic stirring apparatus is put in glycerol mixing, and add gross weight 3-4 alkalescence subset activated water doubly, open magnetic stirring apparatus high-speed stirred 1.2-1.6h, add protein-based surfactant sodium caseinate afterwards, and continue slowly to be stirred to evenly, adding sodium benzoate afterwards, magnetic stirring apparatus is first adopted to strengthen magnetic force rapid stirring 1-2h, slowly adding guar gum, and continue stirring until evenly, high pressure is finally adopted to assist degassed process 4-5h to form uniform and stable body of paste, adopt Sterile vacuum tinning technology, tinning seals and get final product.
CN201510768743.8A 2015-11-12 2015-11-12 Antiallergic gingival protecting toothpaste with high-stability traditional Chinese medicine small molecule compounds added and preparation method Pending CN105232429A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108261343A (en) * 2016-12-30 2018-07-10 杜邦营养生物科学有限公司 Foaming dentifrice composition based on protein

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0517325A (en) * 1991-03-13 1993-01-26 Pias Arise Kk Medicine for dental caries
CN1413571A (en) * 2001-10-29 2003-04-30 梁健 Nanometre toothpaste
CN101708148A (en) * 2009-12-23 2010-05-19 苗辉 Chitosan oligosaccharide toothpaste
CN104606105A (en) * 2015-02-13 2015-05-13 南通蛇类治疗研究所 Plant nanoemulsion toothpaste

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0517325A (en) * 1991-03-13 1993-01-26 Pias Arise Kk Medicine for dental caries
CN1413571A (en) * 2001-10-29 2003-04-30 梁健 Nanometre toothpaste
CN101708148A (en) * 2009-12-23 2010-05-19 苗辉 Chitosan oligosaccharide toothpaste
CN104606105A (en) * 2015-02-13 2015-05-13 南通蛇类治疗研究所 Plant nanoemulsion toothpaste

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108261343A (en) * 2016-12-30 2018-07-10 杜邦营养生物科学有限公司 Foaming dentifrice composition based on protein

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Application publication date: 20160113