CN105213526A - A kind of Chinese medicine being used for the treatment of lichen nitidus - Google Patents
A kind of Chinese medicine being used for the treatment of lichen nitidus Download PDFInfo
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- CN105213526A CN105213526A CN201510719711.9A CN201510719711A CN105213526A CN 105213526 A CN105213526 A CN 105213526A CN 201510719711 A CN201510719711 A CN 201510719711A CN 105213526 A CN105213526 A CN 105213526A
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Abstract
The present invention relates to a kind of Chinese medicine being used for the treatment of lichen nitidus, it is prepared from by the raw medicinal material of following weight proportion: Cortex Saurauiae lantsangensis 9 parts, Herba Pachysandrae Stylosae 9 parts, Radix berchemiae lineatae 13 parts, subdigitate wormwood herb 13 parts, Radix limonii sinensis 12 parts, Flos Caraganae intermediae 9 parts, Flos Loropetali (Herba Loropetali) 8 parts, nine pipe blood 12 parts.Clinical trial certificate, the present invention can safe and effective treatment lichen nitidus.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine being used for the treatment of lichen nitidus.
Background technology
Lichen nitidus is a kind of rare dermatosis, and clinical characters is circular glossiness tiny pimple, no conscious sympton.For the chronic dermatosis that a kind of reason is not bright.Clinical characters is the glossiness little pimple of hatpin head size tool, multiple aggregation, but does not merge, and is apt to occur in the places such as penis, groin and hypogastric region.Primary disease is apt to occur in middle-aged male, has report to betide child person not within minority.Histology has characteristic, prognosis bona.
Skin lesion is that needle point or pin cap are large, circular, and normal skin tone or what is said or talked about rufous flat-top jin rash, glossy, surface can have a small amount of canescence tiny bran shape squama.Pimple can be dispersed in or Assembled distribution, but does not merge, and is sometimes arranged in ring-type.No conscious sympton.Be apt to occur in the portions such as forearm, penis, breast, abdomen and buttocks.The person that betides leg, can the infringement in chronic pigmented purpura.As impaired in fingernail can be muddy plump, present ridge shape or split.Mucosa is asked or is got involved, and the circular pimple of light lark in aggregation, clear-cut margin, diameter is about 1mm, is more common in hard palate and tongue.Skin lesion can disappear in several weeks voluntarily, or last very long.
Medical material present Research involved in the present invention is as follows:
Cortex Saurauiae lantsangensis [another name] spreads Luo Yi, horse ears or side handles of a utensil fruit, sweet heart fruit, nasal mucus fruit, sticky heart fruit, Folium machili velutinae, the great Ye Cortex Eucommiae.[source] is the bark of Actinidiaceae plant billows deep blue Saurauia tristyla.The whole year can adopt.Using fresh herb or dry.[nature and flavor] are the bark of Actinidiaceae plant billows deep blue Saurauia tristyla.The whole year can adopt.Using fresh herb or dry.[function cures mainly] hemostasia and promoting granulation, dissipating blood stasis for subsidence of swelling.Control fracture, traumatic injury is hindered, wound hemorrhage, and urine drenches, chronic osteomyelitis.[usage and dosage] takes orally: decoct soup, 6 ~ 15g.[extracts] " China's book on Chinese herbal medicine ".
Herba Pachysandrae Stylosae [another name] mountain stool, hair impeller stool fruit, ferrum Eriocheir sinensis.[source] medical material Ji Yuan: be rhizome or the Herb of Buxaceae plant hirsutism stool fruit.Gather and store: autumn excavates rhizome, or Herb of choosing, clean, cutting, dries.[nature and flavor] are bitter; Pungent; Temperature.[return through] enters spleen, kidney two warp.[function cures mainly] expelling wind and removing dampness; Promoting blood circulation and stopping pain.Main air pain of dampness syndrome; Numb limbs and tense tendons; Impairment caused by overstrain lumbago; Traumatic injury; Headache.[usage and dosage] takes orally: decoct soup, 3 ~ 9g.[extracts] " China's book on Chinese herbal medicine ".
Radix berchemiae lineatae [another name] Canis familiaris L. foot profit, carry cloud grass, little Flos persicae, mouse grass, Ramulus et Folium Berchemiae Lineatae, mouse crow, molluscum contagiosum head, coal rattan.[source] this product is ratan or the root of Rhamnaceae plant iron gold filled and Herba Berchemiae leiocladae.It is the end of summer, just turning into autumn, before pregnant flower bud, extract young stem and leaf, removing impurity, chopping, using fresh herb or dry; Adopt root, using fresh herb or section are dried after autumn.[nature and flavor] are bitter; Micro-puckery; Flat.[return through] heart; Lung meridian.[function cures mainly] subduing swelling and detoxicating; Hemostatic analgesia; Expelling wind and removing dampness.Main carbuncle furunculosis; Cough spitting of blood; Digestive tract hemorrhage; Traumatic injury; Scald; Rheumatic ostalgia; Wind-fire cough due to lung-heat.[usage and dosage] takes orally: decoct soup, 15-30g; Fresh goods 30-60g.External: appropriate, smashes deposited.[extracts] " China's book on Chinese herbal medicine ".
Subdigitate wormwood herb [another name] wild Artemisia, tea floss, purple bar Artemisia, refer to leaf Artemisia, water Artemisia, Radix Artemisia ordosicae, rice Artemisia.[source] is feverfew subdigitate wormwood herb and the herb without hair subdigitate wormwood herb.Autumn gathers, and using fresh herb or binding are dried.[habitats distribution] is distributed in the ground such as the Inner Mongol, Gansu, Sichuan, Yunnan, Tibet.[nature and flavor] bitter in the mouth; Micro-pungent; Cool in nature.[function cures mainly] heat clearing away; Removing heat from blood; Removing toxic substances; Parasite killing.Main acute calenture; Cough due to lung-heat; Laryngopharynx swelling and pain; Epistaxis; Itching eruption due to wind-heat in blood; Know parasitosis.[usage and dosage] takes orally: decoct soup 9-15g; Or endure cream painting.[extracts] " China's book on Chinese herbal medicine ".
Radix limonii sinensis [another name] mother honker leaf, red shrimp toad leaf.[source] is the herb of gentianaceae plant Radix limonii sinensis.Summer, autumn gather, and clean, dry.[nature and flavor] are bitter; Pungent; Cold in nature.[return through] lung; Liver; Large intestine channel.[function cures mainly] blood circulation promoting and blood stasis dispelling; Clearing and antitussive.Blood stasis mass in the abdomen in main abdomen; Epersalgia cough.[usage and dosage] takes orally: decoct soup, 10 ~ 15g.[extracts] " China's book on Chinese herbal medicine ".
Flos Caraganae intermediae [source] medical material Ji Yuan: be the flower of leguminous plant Caragana intermedia.Gather and store: gathering when spring Mo, early summer are bloomed, using fresh herb or dry.[nature and flavor] are sweet; Temperature.[return through] Liver Channel.[function cures mainly] yin nourishing, suppressing the hyperactive liver.Main dizziness, hypertension.[usage and dosage] takes orally: decoct soup, 6 ~ 15g.[extracts] " China's book on Chinese herbal medicine ".
Flos Loropetali (Herba Loropetali) [another name] paper end flower, chicken are posted, white clear and bright flower, cob wall flower.[source] is the flower of Hamamelidaceae Plants Flos Loropetali (Herba Loropetali).Gather and store: gathering before and after clear and bright and dry in the shade, the dry place of storage.[nature and flavor] property is put down, and taste is micro-sweet puckery.[return through] enters lung, spleen, stomach, large intestine four warp.[function cures mainly] clearing away summer-heat is antipyretic, cough-relieving, hemostasis.Control cough, spitting of blood, seminal emission, excessive thirst, epistaxis, dysentery, has loose bowels, metrorrhagia.[usage and dosage] takes orally: decoct soup, 6 ~ 10g.[extracts] " China's book on Chinese herbal medicine ".
Nine pipe blood [another name] Crisped Ardisia Ardisia gigantifolias, eight pawl dragons, Radix ardisiae brevicaulis, Rhizoma Belamcandae, pig house steward, group's leaf Crisped Ardisia Ardisia gigantifolia, short top top, mandarin orange, Radix Ardisiae Punctatae, blood monkey pawl, black broiler, short sunshade, Radix Ardisiae punctatae, Radix Sophorae Tonkinensis, tire tire of invigorating blood circulation.[source] medical material Ji Yuan: be Herb or the root of Myrsinacea plant nine pipe blood.Gather and store: the 6-7 month adopts, chopping, using fresh herb or dry.[nature and flavor] are bitter; Pungent; Cold in nature.[function cures mainly] heat-clearing and toxic substances removing; Wind-expelling pain-stopping; Promoting blood circulation and detumescence.Main laryngopharynx swelling and pain; Acute toothache; Rheumatic arthralgia; Traumatic injury; Innominate toxic swelling; Venom.[usage and dosage] takes orally: decoct soup, 9 ~ 15g.The careful clothes of [attention] anemia of pregnant woman.[extracts] " China's book on Chinese herbal medicine ".
Summary of the invention
The present invention aims to provide a kind of Chinese medicine being used for the treatment of lichen nitidus, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing lichen nitidus.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine being used for the treatment of lichen nitidus, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Cortex Saurauiae lantsangensis 9 parts, Herba Pachysandrae Stylosae 9 parts, Radix berchemiae lineatae 13 parts, subdigitate wormwood herb 13 parts, Radix limonii sinensis 12 parts, Flos Caraganae intermediae 9 parts, Flos Loropetali (Herba Loropetali) 8 parts, nine pipe blood 12 parts.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor collects outpatient service and lichen nitidus patient 60 example of being in hospital altogether between 2013 04 month ~ 2014 04 month, be divided into treatment group 30 example and matched group 30 example at random, treatment group man 10 example, female 20 example, 18 ~ 45 years old age, 31.5 years old mean age; Matched group man 12 example, female 18 example, 18 ~ 50 years old age, 29.5 years old mean age.2 groups of sexes, age and course of disease comparing difference not statistically significants, have comparability.
Diagnostic criteria
Diagnostic criteria according to the meeting of national lichen nitidus clinical speciality:
(1), characteristic is had.
(2), dermal papilla has and infiltrates based on the stove shape of lymphocyte, histiocyte, visible a small amount of fibroblast, addicted to pigment cell, epithelioid cell, accidental Langhans giant cell, without caseous necrosis, boundary clear, its both sides trochanterellus, to downward-extension, surrounds infiltrating cells spherical in embracing.In infiltration stove, collagen fiber destroy, and elastic fibers disappears, and can have telangiectasis.
(3), blood vessel wall can thicken, and blood vessel can be inaccessible sometimes.It is thinning that stove infiltrates top epidermis, basal layer liquefaction or disappearance.
2, test method
2.1 Therapeutic Method
The capsule that the oral the present invention for the treatment of group obtains according to specific embodiment 3, every day 3 times.14 days courses for the treatment of.
The oral isoniazid of matched group, 0.3g on the one, decoction being taken at a draught; Vitamin A, every day 1 time, each 1.14 days courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Clinic control: sings and symptoms improves 100%;
Effective: sings and symptoms improves more than 60% (containing 60%);
Effective: sings and symptoms improves more than 20% (containing 20%);
Invalid: symptom and sign improve less than 20%.
3.2 therapeutic outcomes are in table 1.
Table 1 liang group comparitive study
Visible, the medicine that the present invention obtains can safe and effective treatment lichen nitidus, has promotional value.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Take: Cortex Saurauiae lantsangensis 9 grams, Herba Pachysandrae Stylosae 9 grams, Radix berchemiae lineatae 13 grams, subdigitate wormwood herb 13 grams, Radix limonii sinensis 12 grams, Flos Caraganae intermediae 9 grams, Flos Loropetali (Herba Loropetali) 8 grams, nine pipe blood 12 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of lichen nitidus.Oral, every bu Morning Afternoon Evening is taken for three times.
Embodiment 2
Take: Cortex Saurauiae lantsangensis 9 grams, Herba Pachysandrae Stylosae 9 grams, Radix berchemiae lineatae 13 grams, subdigitate wormwood herb 13 grams, Radix limonii sinensis 12 grams, Flos Caraganae intermediae 9 grams, Flos Loropetali (Herba Loropetali) 8 grams, nine pipe blood 12 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of lichen nitidus.Oral, every bu Morning Afternoon Evening is taken for three times.
Embodiment 3
Take: Cortex Saurauiae lantsangensis 9 grams, Herba Pachysandrae Stylosae 9 grams, Radix berchemiae lineatae 13 grams, subdigitate wormwood herb 13 grams, Radix limonii sinensis 12 grams, Flos Caraganae intermediae 9 grams, Flos Loropetali (Herba Loropetali) 8 grams, nine pipe blood 12 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of lichen nitidus.Oral, every bu Morning Afternoon Evening is taken for three times.
Claims (4)
1. one kind is used for the treatment of the Chinese medicine of lichen nitidus, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Cortex Saurauiae lantsangensis 9 parts, Herba Pachysandrae Stylosae 9 parts, Radix berchemiae lineatae 13 parts, subdigitate wormwood herb 13 parts, Radix limonii sinensis 12 parts, Flos Caraganae intermediae 9 parts, Flos Loropetali (Herba Loropetali) 8 parts, nine pipe blood 12 parts.
2. a kind of Chinese medicine being used for the treatment of lichen nitidus as claimed in claim 1, it is characterized in that, its preparation method is: take: Cortex Saurauiae lantsangensis 9 parts, Herba Pachysandrae Stylosae 9 parts, Radix berchemiae lineatae 13 parts, subdigitate wormwood herb 13 parts, Radix limonii sinensis 12 parts, Flos Caraganae intermediae 9 parts, Flos Loropetali (Herba Loropetali) 8 parts, nine pipe blood 12 parts; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.
3. a kind of Chinese medicine being used for the treatment of lichen nitidus as claimed in claim 1, it is characterized in that, its preparation method is: take: Cortex Saurauiae lantsangensis 9 parts, Herba Pachysandrae Stylosae 9 parts, Radix berchemiae lineatae 13 parts, subdigitate wormwood herb 13 parts, Radix limonii sinensis 12 parts, Flos Caraganae intermediae 9 parts, Flos Loropetali (Herba Loropetali) 8 parts, nine pipe blood 12 parts; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.
4. a kind of Chinese medicine being used for the treatment of lichen nitidus as claimed in claim 1, it is characterized in that, its preparation method is: take: Cortex Saurauiae lantsangensis 9 parts, Herba Pachysandrae Stylosae 9 parts, Radix berchemiae lineatae 13 parts, subdigitate wormwood herb 13 parts, Radix limonii sinensis 12 parts, Flos Caraganae intermediae 9 parts, Flos Loropetali (Herba Loropetali) 8 parts, nine pipe blood 12 parts; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, obtains capsule; Above-mentioned part all refers to weight portion.
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Citations (1)
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CN1172674A (en) * | 1997-08-29 | 1998-02-11 | 刘进成 | Chinese medicinal herb composition for treating skin disease |
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CN1172674A (en) * | 1997-08-29 | 1998-02-11 | 刘进成 | Chinese medicinal herb composition for treating skin disease |
Non-Patent Citations (1)
Title |
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范瑞强: "《中西医结合临床皮肤性病学》", 30 April 2003 * |
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