CN102512526B - Medicine for treating early bone injury and soft tissue injury - Google Patents

Abstract

The invention relates to a medicine for treating early bone injury and soft tissue injury, comprising raw materials in the following parts by weight: 3-15 parts of radix bupleuri, 3-15 parts of ground beeltle, 5-20 parts of angelica sinensis, 5-20 parts of ligusticum wallichii, 5-20 parts of medicinal cyathula root, 5-20 parts of peach kernels, 5-20 parts of herba lycopi, 3-15 parts of frankincense, 3-15 parts of myrrh, 5-20 parts of fructus aurantii, 5-20 parts of rhizoma corydalis, 3-15 parts of fried rheum officinale, 5-20 parts of plantain seed and 2-15 parts of raw liquorice. The medicine is capsule. The medicine disclosed by the invention has the effects of promoting blood circulation and removing blood stasis, relaxing tendons and reuniting bones, regulating qi and relieving pain, as well as detoxifying and eliminating swelling; and the medicine is suitable for treating the patient in the early stage of bone fracture and soft tissue injury.

Description

A kind of medicine for the treatment of early stage bone injury and soft tissue injury

Technical field

The present invention relates to a kind of medicine of set a broken bone, particularly, the present invention relates to a kind of medicine for the treatment of early stage bone injury and soft tissue injury.

Background technology

It is orthopedics department commonly encountered diseases frequently-occurring disease that traumatic injury, wound violence, contingency cause fracture, soft tissue injury, and early stage appropriate treatment is in time the important key that guarantees rehabilitation, its healing to fracture, reduce complication, functional rehabilitation, palliates the agonizing sufferings, and has a very important role.

Fracture early symptom mainly contains: one, whole body performance: (1) shock: for multiple fracture, fracture of pelvis, Fracture of femur, spinal fracture and serious open bone.Patient Chang Yin widely soft tissue injury, bleed profusely, have an intense pain or concurrent visceral injury etc. and cause shock.(2) heating: fracture has a large amount of internal hemorrhages, and during absorption of hematoma, body temperature slightly raises, during open fracture fervescence, should consider the possibility infecting.Two, topical manifestations: the topical manifestations of fracture comprises proprietary sign and other performances of fracture.The proprietary sign of fracture: (1) deformity: fracture segment displacement can make suffering limb profile change, main manifestations is for shortening; (2) abnormal movement: abnormal activity, appears in the immobile position of normal condition lower limb body after fracture.(3) bony crepitus or bone rubbing feeling: after fracture, during two fracture end phase mutual friction, can produce bone and get rid of sound or bone rubbing feeling.Above three kinds of signs, as long as find one of them, can be made a definite diagnosis, but have no this three kinds of sign persons, can not get rid of the possibility of fracture, as intercalation fracture, fissure fracture.

Fracture can be attended by the generation of complication in early days, has serious harm.The early complication of fracture mainly contains: (1) shock: belong to traumatic shock, be due to severe trauma, the massive hemorrhage that causes of fracture or vitals damage more; (2) fat embolism syndrome: be that bone marrow is destroyed due to hematoma overtension in fracture pulp cavity, fat drop enters in the venous sinus breaking, and can cause lung, fat embolism of brain.So the patient of long bone fracture fat embolism that may occur together clinically.Clinical respiratory insufficiency, the cyanosis of occurring, rabat has popularity pulmonary consolidation.The low blood oxygen of tremulous pulse can cause dysphoria, drowsiness, and even stupor is dead; (3) important internal organs damage, such as liver, rupture of spleen, injury of lung, bladder and injury of urethra, damage etc. cures the wound; (4) important surrounding tissue damage: important blood vessels damage is more common the arterial injury due to fracture of femoral condyle, before tibia epimere fracture can be damaged shin or injury of posterior tibial artery, the far-end of supracondylar of humerus fractures causes injury of brachial artery; Peripheral nerve injury is common to be had in humerus, lower 1/3 intersection fracture and injury radial nerve, fracture of fibular neck easy damaged common peroneal nerve; Spinal cord injury mostly occurs when cervical part of esophagus and lumbar-thoracic spine are fractured, dislocated, and can occur the paralysis in various degree below lesion level, even lifelong disabled; (5) osteofascial compartment syndrome: muscle and nerve in the bone fascial bursa being formed by bone, interosseous membrane, intermuscular septum and deep fascia, a series of early stage syndrome producing because of acute ischemia.

The reasons such as various acute traumas or chronic strain and own disease pathology that refer to soft tissue injury cause the pathological lesion of the tissues such as the skin of human body, subcutaneous shallow deep fascia, muscle, tendon, stndon sheath, ligament, joint capsule, synovial bursae, intervertebral disc, peripheral nerve blood vessel, are called soft tissue injury.Clinical manifestation: pain, swelling, deformity, dysfunction.

After acute injury of soft tissue occurs, main manifestations is pain, and movable function is affected, and should do suitably to process according to different situations at the scene.If open wound generally has external haemorrhage, hemorrhage processing be please refer to hemorrhage processing below, to its wound, should note protection (as wrapping), in case infect, then to medical institutions, do thorough processing.To closed injury, as being lighter spraining, generally only there is hypodynia in short-term, have no significant effect, heavier turning round, draw, dampen often has obvious tumefaction (or soft tissue internal hemorrhage) and pain, and processing is at the scene mainly to prevent that its traumatic condition from continuing to increase the weight of, control swelling and pain, because hematoma in excessive swelling or tissue, can increase the difficulty for the treatment of, extend the period for the treatment of.Field control swelling or to organize the best method of internal hemorrhage be pressure dressing, though someone proposes first to use ice compress, make to wrap up again after vasoconstriction, its object is not also outward minimizing or prevents hemorrhage and swelling, but in most cases, scene is difficult to find ice cube or cryogen external application at once, after finding ice compress if mechanically wait, wrap up again, hemorrhage and swelling early forms the sixth of the twelve Earthly Branches, at this moment measure is without large effect, therefore the most effective way is exactly first directly to press injury with hands at the scene, press and both can prevent that it is hemorrhage, swelling occurs, also there is certain analgesic activity, another hands is taken out rapidly sark lining and is pressed subordinate injury, then with binder or cloth, carry out pressure dressing, Zai Song medical institutions are for further processing, do like this due to not hemorrhage and swelling, very favourable to its recovery.Acute soft tissue injury be must guard against as far back as part, injury and was made too much maneuver, and the treatment skill of particularly too exerting oneself is done like this and easily impelled hemorrhage, swelling to increase the weight of, and traumatic condition is more worsened.

CN101099805A discloses a kind of Chinese patent medicine for the treatment of bone injury diseases, and its raw material by following weight portion prepares: Radix Notoginseng 8～12, Radix Dipsaci 8～12, Rhizoma Drynariae 10～14, Flos Carthami 6～10, Radix Glycyrrhizae 5～9, Cornu Cervi Pantotrichum 10～14, Sanguis Draxonis 8～12, the Cortex Eucommiae 10～14.The present invention adopts pure Chinese medicinal preparation, by promoting blood circulation to remove blood stasis, and reducing swelling and alleviating pain, hemostasis the meridian dredging, invigorating the liver and kidney, the healing that accelerated bone is sick and wounded.

CN101637589A discloses a kind of Chinese medicine composition for the treatment of early stage bone injury and soft tissue injury and preparation method thereof.Said composition is comprised of Herba Lycopi, Radix Angelicae Sinensis, Rhizoma Corydalis, Semen Persicae, Radix Salviae Miltiorrhizae, Radix Rubiae, Radix Rehmanniae, Herba Artemisiae Anomalae, Rhizoma Curcumae, Radix Bupleuri, Lignum Sappan, Radix Paeoniae Rubra, Pericarpium Citri Reticulatae, Radix Et Rhizoma Rhei, Caulis Akebiae, Radix Glycyrrhizae, Radix Notoginseng.Pharmaceutical composition of the present invention adds conventional adjuvant to be prepared into the dosage form of clinical acceptance by galenic pharmacy method, as capsule, tablet, decoction, the watered pill or granule etc.Pharmaceutical composition of the present invention has the effects such as blood circulation promoting and blood stasis dispelling, cooling blood for hemostasis, promoting the circulation of QI to relieve pain.

At present in the medicine of set a broken bone, mostly contain Radix Notoginseng, the blood circulation promoting and blood stasis dispelling effect of Radix Notoginseng is poor and can not removing heat from blood, affects final therapeutic effect.Radix Et Rhizoma Rhei has the effect of blood circulation promoting and blood stasis dispelling, but Radix Et Rhizoma Rhei has obvious discharge function, and side effect is larger.In existing medicine, can reach the medicine of blood circulation promoting and blood stasis dispelling, cooling blood for hemostasis, removing toxic substances and promoting subsidence of swelling and promoting the circulation of QI to relieve pain effect seldom simultaneously.Add, the medicine of set a broken bone mostly is medical herbs, and because of decoction medical herbs, to patient, taking and carry all has inconvenience, and mouthfeel is poor, and patient's compliance is poor, to treatment, brings difficulty.

Summary of the invention

For the deficiencies in the prior art, the object of the present invention is to provide the medicine of a kind of set a broken bone and soft tissue injury.

Bone injury and soft tissue injury differential diagnosis in tcm belong to that qi depression to blood stasis, muscles and bones are impaired, noxious dampness retardance, and medicine of the present invention is by " symptomatic treatment in acute condition " principle, and blood circulation promoting and blood stasis dispelling, regulating QI to relieve pain, removing toxic substances and promoting subsidence of swelling are the rule for the treatment of, are applicable to the early treatment of fracture and soft tissue injury.

The medicine of the early stage bone injury of described treatment and soft tissue injury, comprises the raw material of following weight portion:

Radix Bupleuri 3～15, Eupolyphaga Seu Steleophaga 3～15, Radix Angelicae Sinensis 5～20, Rhizoma Chuanxiong 5～20, Radix Cyathulae 5～20, Semen Persicae 5～20, Herba Lycopi 5～20, Olibanum 3～15, Myrrha 3～15, Fructus Aurantii 5～20, Rhizoma Corydalis 5～20, Radix Et Rhizoma Rhei (parched) 3～15, Semen Plantaginis 5～20, Radix Glycyrrhizae 2～15.

Radix Bupleuri, clearind deficient heat Chinese medicine, feeble QI is fragrant, mildly bitter flavor, for cold, fever, alternate attack of chill and fever, malaria, stagnation of QI due to depression of the liver, sternal rib pain, proctoptosis, uterus come off, menoxenia.

After fracture, fracture has a large amount of internal hemorrhages, and during absorption of hematoma, body temperature slightly raises.Effective ingredient volatile oil in Radix Bupleuri (eugenol, caproic acid, γ-undecanoic acid lactone and to methoxybenzene diketone), saikoside (sapogenin A has the effect of heat clearing away cooling, and body temperature is reduced).The effective ingredient saponin of Radix Bupleuri has anti-inflammatory effect, can reduce the inflammation after fracture and soft tissue injury.Meanwhile, the Bupleurum chinense polysaccharide in Radix Bupleuri has the effect of Promote immunity function.

Eupolyphaga Seu Steleophaga, the female worm dry body for Corydiidae insecticide eupolyphoge sinensis or Ji eupolyphoge sinensis, has another name called eupolyphoge sinensis.It is cold in nature, taste becomes, poisonous, is the good medicine of blood circulation promoting and blood stasis dispelling.It can enter conscience spleen three warps, there is removing blood stasis, removing mass, dredging collateral, reason wound and reunion of bone, reducing swelling and alleviating pain, the stimulating milk secretion effect such as stimulate the menstrual flow, be treating blood disorders traumatology key medicine, be applicable to the diseases such as cancer abdominal mass is gathered, amenorrhea due to stagnation of blood, postnatal blood stasis stomachache, traumatic injury, swollen and rigid tongue, congenital deformity of the tongue.

Radix Angelicae Sinensis, herbaceos perennial, at distribution in China in Gansu, all there is cultivation in Yunnan, Sichuan, Qinghai, Shaanxi, Hunan, Hubei, Deng Di， various places, Guizhou.The root of Radix Angelicae Sinensis can be used as medicine, and is one of the most frequently used Chinese medicine.Motherland's medical science thinks, Radix Angelicae Sinensis sweet in the mouth and weighing, therefore specially can enrich blood, its gas is light and pungent, thus again can promoting the circulation of blood, invigorating middle warmer has, in row, has benefit, is the key medicine in blood.Thereby it can be enriched blood, can invigorate blood circulation again, both can stimulate the menstrual flow, again can be active.

Rhizoma Chuanxiong, original name rhizome of chuanxiong Qiong, pungent temperature rise is loose, a kind of Chinese medicinal plant, is usually used in blood-activating and qi-promoting, wind-expelling pain-stopping, Main Cultivation in Sichuan, the ground such as Yunnan, Guizhou, Guangxi, Hubei.Rhizoma Chuanxiong has the effects such as blood-activating and qi-promoting, wind-expelling pain-stopping, dissipating depression of QI dampness.Chinese medical theory is thought Rhizoma Chuanxiong, and " Xin Xiang walks to alter and circulation of qi promoting, and blood circulation promoting and blood stasis dispelling is with hemostasis, and the up head and dispeling the wind, is lowered to the sea of blood with regulating menstruation.And outer thorough fur, bypass extremity, are the gas medicine in blood ".Therefore be usually used in taking orally, cure mainly the diseases such as dizzy, the rheumatic arthralgia of headache, costa sternales twinge, treating swelling and pain by traumatic injury, amenorrhea dysmenorrhea, menoxenia, arthralgia due to cold spasm, ulcer sores and postpartum stagnation stomachache.

Radix Cyathulae, the dry root of amaranthaceous plant Radix Cyathulae.Autumn, two seasons of winter excavate, and remove removing LU, fibrous root and silt, dry or shine to half-dried, and heap is put back to profit, then a heatable brick bed done or dry.Property sweet, micro-hardship, flat.Return liver, kidney channel.It cures mainly eliminating blood stasis and inducing menstruation, easing joint movement, inducing diuresis for treating stranguria syndrome.For amenorrhea lump in the abdomen, retention of placenta, arthralgia, flaccidity of the lower limbs clonic spasm of the muscle, hematuria stranguria with blood, injury from falling down.

Semen Persicae, another name Radix Fici Hirtae core, almond core, large Semen Persicae.Seed for Folium rosae multiflorae plant Fructus Persicae.Semen Persicae bitter but sweet flavor, property is flat.Bitter can drop-down leading down with removing blood stasis with potent drugs, sweet and and smooth QI and blood with tissue regeneration promoting, therefore there is the effect of promoting blood circulation to restore menstrual flow, removing blood stasis to promote tissue regeneration, can be used for traumatic injury etc.To amenorrhea, in abdomen, there is the disease of blood stasis caking to take.Its matter profit can also be moisturized laxation, is applicable to the constipation of large intestine deficiency of body fluid.Still can invigorate blood circulation with eliminating carbuncle, can control acute appendicitis, lung abscess.

Herba Lycopi, another name: lycopus lucidus, Rhizoma Lycopi Lucidi, Phryganeajaponica Ml., Herba Lycopi.Slightly warm in nature, bitter in the mouth, pungent.Chemical composition: containing volatile oil flavonoid glycoside, Saponin, phenols, saccharide and tannin.Slightly warm in nature, bitter in the mouth, pungent, has blood circulation promoting and blood stasis dispelling, and the effect of line water detumescence can be used for the treatment of bone injury and soft tissue injury.

Olibanum, the smoked Lu Xiang of another name, is the gum resin of olive subject plant Boswellia carterii Birdw.Main product Somalia, Ethiopia.Property acrid, bitter, warm.Enter the heart, liver, spleen channel.Invigorate blood circulation, circulation of qi promoting, pain relieving.Control the epigastric pain of the stasis blocking stagnation of QI, rheumatic arthralgia, traumatic injury, dysmenorrhea, puerperal abdonimal pain.

Myrrha, property is bitter, pungent, flat, and the dry resin for olive subject plant Herba Violae tree or Ha Didingshu, has another name called myrrh.Main product is in African Somalia, Ethiopia and India and other places.The Liquid Paraffin gum resin that collection is oozed out by place, bark crack becomes rufous and hard nahlock in air.After smashing, fry to coke black and apply.Cure mainly breast abdomen stasis of blood pain, dysmenorrhea, amenorrhea, lump in the abdomen, traumatic injury, carbuncle skin infection, acute appendicitis, conjunctival congestion and swelling pain.There are the effects such as promoting blood circulation and stopping pain, detumescence and promoting granulation.

Fructus Aurantii: be the dry immature fruit of rutaceae Citrus aurantium Linn. and variety thereof.Gather when peel is still green July, from middle part crosscut, is two halves, dries or cold drying.Nature and flavor are bitter, pungent, sour, temperature.Regulating the flow of QI to ease the stomach, the stagnant relieving distension of row.For the breast side of body stagnation of QI, distension pain, accumulation of food in the stomach and intes tine due to indigestion, stops in phlegm retention; Gastroptosis, proctoptosis, uterine prolapse etc.They can promoting the circulation of QI to relieve pain, effectively alleviate the pain of bone injury and soft tissue injury.

Rhizoma Corydalis, the tuber of papaveraceae plant corydalis and tooth lobe Rhizoma Corydalis.Acrid in the mouth, hardship, temperature.Pericardium, liver, spleen, lung.Promoting blood circulation to remove blood stasis, promoting the circulation of QI to relieve pain, effectively alleviate the pain of bone injury and soft tissue injury.

Radix Et Rhizoma Rhei is being collectively referred to as of perennial plant of multiple Polygonaceae Rheum, is also the title of Chinese crude drug.In the document of CHINESE REGION, the todaiwo,rhizoma often that " Radix Et Rhizoma Rhei " refers to.In China, Radix Et Rhizoma Rhei is mainly done medicinal, but in Europe and the Middle East, their Radix Et Rhizoma Rhei often refers to the Rheum kind that other several work is edible, and stem is red.Gas delicate fragrance, bitter in the mouth is and micro-puckery, and that chews sticks to one's teeth, and has sand feeling.Autumn Mo in the withered or inferior spring of stem and leaf excavates before germinateing.Remove radicula, scrape off crust, valve cutting or section, rope is worn bunchiness and is dried or convection drying.Chinese herb rhubarb has attacks the effects such as stagnant, clearing away damp-heat, pathogenic fire purging, removing heat from blood, blood stasis dispelling, removing toxic substances.

Radix Et Rhizoma Rhei (parched), rhubarb tablets or piece, put in pot, and intense fire is fried when appearance is black and is taken out, and spreads out and cools.Radix Et Rhizoma Rhei, abnormal smells from the patient is deep, walks and does not keep, the through part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels, discharge function is high strong, but the gas that easily injures one's stomach.After parch to black its discharge function extremely a little less than, and have anastalsis, can be used for playing in bone injury and soft tissue injury the effect of hemostasis.

Semen Plantaginis, has another name called Herba Plantaginis reality, Rana limnocharis clothing, pig ear tassel, phoenix eyes Semen Plantaginis, and this product is the dry mature seed of Plantaginaceae plant Herba Plantaginis.Be all wild.The fruit ear of gathering during seed maturity in summer, two season of autumn, dries, and rubs seed, removes impurity.Main product in Heilungkiang, the ground such as Liaoning, Hebei.Former plant is born in hill, roadside, flower nursery or vegetable garden.Happiness warm and moist weather, cold-resistant, all can grow in level land, mountain area, to soil, requires not tight.This product is sweet in flavor and cold in property, enters kidney, bladder, liver, lung meridian, and function relieving stranguria by diuresis, eliminating dampness by diuresis antidiarrheal, liver heat removing and eyesight improving, removing heat-phlegm are medicinal herbs most in use.

Radix Glycyrrhizae is pulse family herbaceos perennial.In late autumn, pod splits, and seed is taken a walk on the ground large with the wind, natural breeding.Stem is tall and straight upright; Root is as cylinder, three or four centimetres of diameters, and large five or six centimetres, long more than one meter, elder reaches three or four meters.There is invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, the effect of coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.It is combined with Radix Bupleuri, Semen Plantaginis, has good heat-clearing toxin-expelling functions.

Above raw material, after optimum organization of the present invention, is made the preparation of set a broken bone and soft tissue injury, not only can bring into play separately original effect, more can further strengthen its curative effect, set a broken bone and soft tissue injury is better than to the effect of existing medicine.

As preferred version, described medicine comprises the raw material of following weight portion:

Radix Bupleuri 3～10, Eupolyphaga Seu Steleophaga 3～10, Radix Angelicae Sinensis 5～15, Rhizoma Chuanxiong 5～15, Radix Cyathulae 5～15, Semen Persicae 5～15, Herba Lycopi 5～15, Olibanum 3～10, Myrrha 3～10, Fructus Aurantii 5～15, Rhizoma Corydalis 5～15, Radix Et Rhizoma Rhei (parched) 3～10, Semen Plantaginis 5～15, Radix Glycyrrhizae 3～8.

More electedly, described medicine comprises the raw material of following weight portion:

Radix Bupleuri 6, Eupolyphaga Seu Steleophaga 6, Radix Angelicae Sinensis 10, Rhizoma Chuanxiong 10, Radix Cyathulae 10, Semen Persicae 10, Herba Lycopi 10, Olibanum 6, Myrrha 6, Fructus Aurantii 10, Rhizoma Corydalis 10, Radix Et Rhizoma Rhei (parched) 6, Semen Plantaginis 10, Radix Glycyrrhizae 5.

The effective ingredient that the present invention's composition described above is described medicine." comprising " of the present invention, mean it except described component, can also comprise other components, these other components give described medicine different characteristics.In addition, " comprising " of the present invention, can also replace with enclosed " being " or " by ... form ".

Medicine in existing set a broken bone and soft tissue injury mostly is Chinese herbal medicine, and because of decoction medical herbs, to patient, taking and carry all has inconvenience, and mouthfeel is poor, and patient's compliance is poor, to treatment, brings difficulty.Medicine of the present invention is capsule.Capsule preparations is convenient to take, and mouthfeel is good, can effectively improve and eliminate clinical symptoms.

Medicine of the present invention has the effect of blood circulation promoting and blood stasis dispelling, relaxing muscles and tendons symplectic bone, regulating QI to relieve pain, removing toxic substances and promoting subsidence of swelling, is applicable to fracture and the early stage patient's of soft tissue injury treatment.

Medicine of the present invention can be used for traumatic injury, wound violence, contingency, trauma fracture, bones and muscles injury in soft tissue injury commitment, the treatment in the fracture due to qi depression to blood stasis, pyretic toxicity pent up, the injury of tendon and muscle, hematoma, pain, swelling, dysfunction etc.; Also can be used for wound violence, traumatic injury etc. to cause muscles and bones injured simultaneously, qi depression to blood stasis, and the stagnant hematoma of the venation stasis of blood, pyretic toxicity pents up the treatment in swelling.

Medicine of the present invention has important effect in the medicine of the preparation early stage bone injury for the treatment of and soft tissue injury.

Compared with prior art, tool of the present invention has the following advantages:

Medicine of the present invention is formulated according to " symptomatic treatment in acute condition " legislation principles, take blood circulation promoting and blood stasis dispelling as main, coordinates regulating QI to relieve pain, regulate the flow of vital energy and can invigorate blood circulation, blood circulation promoting and blood stasis dispelling is the fluence network of promoting blood circulation, more assistant removing pathogenic heat from blood and toxic substance from the body, the agent of inducing diuresis to remove edema, no matter in blood stasis dispelling, control damage, the hematoma that disappears of invigorating blood circulation, or heat-clearing and toxic substances removing controls swelling, and the regulating QI machine of regulating the flow of vital energy is with pain relieving, all be applicable to fracture and the early stage patient's of soft tissue injury treatment, have no side effect and untoward reaction.

Medicine of the present invention is made capsule and is convenient to take, and mouthfeel is good, can effectively improve and eliminate clinical symptoms.Use for many years clinically, therapeutic effect is obvious, uses after 12 days, and 94% patient cures substantially, and without any side effects, and untoward reaction and malpractice did not occur, and is deeply subject to patient's approval.

The specific embodiment

For ease of understanding the present invention, it is as follows that the present invention enumerates embodiment.Those skilled in the art should understand, described embodiment helps to understand the present invention, should not be considered as concrete restriction of the present invention.

Embodiment 1

Get Radix Bupleuri 6g, Eupolyphaga Seu Steleophaga 6g, Radix Angelicae Sinensis 12g, Rhizoma Chuanxiong 12g, Radix Cyathulae 12g, Semen Persicae 12g, Herba Lycopi 12g, Olibanum 6g, Myrrha 6g, Fructus Aurantii 12g, Rhizoma Corydalis 12g, Radix Et Rhizoma Rhei (parched) 6g, Semen Plantaginis 12g, Radix Glycyrrhizae 5g, grind to form powdery, according to capsule required dosage, be divided into equal weight umber, make capsule, every capsules effective ingredient is 1.338g.

Embodiment 2

Get Radix Bupleuri 3g, Eupolyphaga Seu Steleophaga 3g, Radix Angelicae Sinensis 5g, Rhizoma Chuanxiong 5g, Radix Cyathulae 5g, Semen Persicae 5g, Herba Lycopi 5g, Olibanum 3g, Myrrha 3g, Fructus Aurantii 5g, Rhizoma Corydalis 5g, Radix Et Rhizoma Rhei (parched) 3g, Semen Plantaginis 5g, Radix Glycyrrhizae 2g, grind to form powdery, according to capsule required dosage, be divided into equal weight umber, make capsule, every capsules effective ingredient is 1.338g.

Embodiment 3

Get Radix Bupleuri 15g, Eupolyphaga Seu Steleophaga 15g, Radix Angelicae Sinensis 20g, Rhizoma Chuanxiong 20g, Radix Cyathulae 20g, Semen Persicae 20g, Herba Lycopi 20g, Olibanum 15g, Myrrha 15g, Fructus Aurantii 20g, Rhizoma Corydalis 5g, Radix Et Rhizoma Rhei (parched) 15g, Semen Plantaginis 20g, Radix Glycyrrhizae 15g, grind to form powdery, according to capsule required dosage, be divided into equal weight umber, make capsule, every capsules effective ingredient is 1.338g.

Embodiment 4

Get Radix Bupleuri 8g, Eupolyphaga Seu Steleophaga 9g, Radix Angelicae Sinensis 14g, Rhizoma Chuanxiong 15g, Radix Cyathulae 12g, Semen Persicae 10g, Herba Lycopi 10g, Olibanum 8g, Myrrha 8g, Fructus Aurantii 14g, Rhizoma Corydalis 12g, Radix Et Rhizoma Rhei (parched) 6g, Semen Plantaginis 12g, Radix Glycyrrhizae 3g, grind to form powdery, according to capsule required dosage, be divided into equal weight umber, make capsule, every capsules effective ingredient is 1.338g.

Embodiment 5

Get Radix Bupleuri 7g, Eupolyphaga Seu Steleophaga 5g, Radix Angelicae Sinensis 12g, Rhizoma Chuanxiong 10g, Radix Cyathulae 12g, Semen Persicae 12g, Herba Lycopi 12g, Olibanum 9g, Myrrha 8g, Fructus Aurantii 12g, Rhizoma Corydalis 15g, Radix Et Rhizoma Rhei (parched) 8g, Semen Plantaginis 12g, Radix Glycyrrhizae 6g, grind to form powdery, according to capsule required dosage, be divided into equal weight umber, make capsule, every capsules effective ingredient is 1.338g.

Embodiment 6

Get Radix Bupleuri 5g, Eupolyphaga Seu Steleophaga 9g, Radix Angelicae Sinensis 18g, Rhizoma Chuanxiong 17g, Radix Cyathulae 12g, Semen Persicae 12g, Herba Lycopi 12g, Olibanum 5g, Myrrha 7g, Fructus Aurantii 10g, Rhizoma Corydalis 12g, Radix Et Rhizoma Rhei (parched) 9g, Semen Plantaginis 10g, Radix Glycyrrhizae 7g, grind to form powdery, according to capsule required dosage, be divided into equal weight umber, make capsule, every capsules effective ingredient is 1.338g.

Embodiment 7

Get Radix Bupleuri 6g, Eupolyphaga Seu Steleophaga 6g, Radix Angelicae Sinensis 10g, Rhizoma Chuanxiong 10g, Radix Cyathulae 10g, Semen Persicae 10g, Herba Lycopi 10g, Olibanum 6g, Myrrha 6g, Fructus Aurantii 10g, Rhizoma Corydalis 10g, Radix Et Rhizoma Rhei (parched) 6g, Semen Plantaginis 10g, Radix Glycyrrhizae 5g, grind to form powdery, according to capsule required dosage, be divided into equal weight umber, make capsule, every capsules effective ingredient is 1.338g.

Applicant's statement, person of ordinary skill in the field is on the basis of above-described embodiment, by the concrete content point value of above-described embodiment component, combined with the technical scheme of summary of the invention part, thereby the new numerical range producing, also be one of record scope of the present invention, the application, for making description simple and clear, is no longer enumerated these numerical rangies.

For showing the therapeutical effect of medicine of the present invention to early stage bone injury and soft tissue injury, select the patient of the early stage bone injurys of 800 example and soft tissue injury to observe, select patient's 600 examples of early stage bone injury that medical history, the state of an illness, age and former Therapeutic Method are suitable and soft tissue injury as a control group simultaneously.The capsule that test group adopts the embodiment of the present invention 7 to make is treated, and matched group is treated according to a conventional method, and clinical test results is as shown in table 1 below:

Therapeutic Method: the capsule that adopts embodiment 7 to make, oral, each 3-4 grain, three times on the one, child's consumption reduces by half.

Function with cure mainly: blood circulation promoting and blood stasis dispelling, relaxing muscles and tendons symplectic bone, regulating QI to relieve pain, removing toxic substances and promoting subsidence of swelling, be applicable to fracture and the early stage patient's of soft tissue injury treatment.

Table 1 clinical test results

Use capsule of the present invention two days later, 96% patient has the phenomenons such as local pain, tenderness, swelling, ecchymosis disappear; After 8 days, 95% patient's local pain, tenderness are alleviated rapidly, and swelling, ecchymosis are eliminated substantially, and functional activity has obvious recovery; Use after 12 days, 94% the various symptoms of patient disappear substantially, and functional activity recovers completely, and all the other patients recover, and estimate that after 3～5 days, symptom can all disappear, and recover normal.And functional activity recovers still not obvious while using the matched group to 12 day of traditional therapy, effect is not remarkable.

Clinical drug of the present invention is used more than 10 years, treats approximately more than 10,000 person-time, facts have proved that curative effect is good, there are no the case that causes abdominal pain diarrhea and other toxicities, occurs.

Applicant's statement, the present invention illustrates detailed composition and the preparation method of medicine of the present invention by above-described embodiment, but the present invention is not limited to above-mentioned detailed component and preparation method, do not mean that the present invention must rely on above-mentioned detailed component and preparation method could be implemented.Person of ordinary skill in the field should understand, any improvement in the present invention, to the selection of the interpolation of the equivalence replacement of each raw material of product of the present invention and auxiliary element, concrete mode etc., within all dropping on protection scope of the present invention and open scope.

Claims (5)

1. a medicine for the treatment of early stage bone injury and soft tissue injury, is characterized in that, the raw material of following weight portion, consists of:

Radix Bupleuri 3～15, Eupolyphaga Seu Steleophaga 3～15, Radix Angelicae Sinensis 5～20, Rhizoma Chuanxiong 5～20, Radix Cyathulae 5～20, Semen Persicae 5～20, Herba Lycopi 5～20, Olibanum 3～15, Myrrha 3～15, Fructus Aurantii 5～20, Rhizoma Corydalis 5～20, Radix Et Rhizoma Rhei (parched) 3～15, Semen Plantaginis 5～20, Radix Glycyrrhizae 2～15.

2. medicine as claimed in claim 1, is characterized in that, the raw material of following weight portion, consists of:

Radix Bupleuri 3～10, Eupolyphaga Seu Steleophaga 3～10, Radix Angelicae Sinensis 5～15, Rhizoma Chuanxiong 5～15, Radix Cyathulae 5～15, Semen Persicae 5～15, Herba Lycopi 5～15, Olibanum 3～10, Myrrha 3～10, Fructus Aurantii 5～15, Rhizoma Corydalis 5～15, Radix Et Rhizoma Rhei (parched) 3～10, Semen Plantaginis 5～15, Radix Glycyrrhizae 3～8.

3. medicine as claimed in claim 1 or 2, is characterized in that, the raw material of following weight portion, consists of:

Radix Bupleuri 6, Eupolyphaga Seu Steleophaga 6, Radix Angelicae Sinensis 10, Rhizoma Chuanxiong 10, Radix Cyathulae 10, Semen Persicae 10, Herba Lycopi 10, Olibanum 6, Myrrha 6, Fructus Aurantii 10, Rhizoma Corydalis 10, Radix Et Rhizoma Rhei (parched) 6, Semen Plantaginis 10, Radix Glycyrrhizae 5.

4. medicine as claimed in claim 1, is characterized in that, described medicine is capsule.

5. the application of the medicine as described in claim 1-4 any one in the medicine of the preparation early stage bone injury for the treatment of and soft tissue injury.