CN101607022B - Chinese medicament bone-knitting pellet preparation - Google Patents
Chinese medicament bone-knitting pellet preparation Download PDFInfo
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- CN101607022B CN101607022B CN2008100170416A CN200810017041A CN101607022B CN 101607022 B CN101607022 B CN 101607022B CN 2008100170416 A CN2008100170416 A CN 2008100170416A CN 200810017041 A CN200810017041 A CN 200810017041A CN 101607022 B CN101607022 B CN 101607022B
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Abstract
The invention discloses a Chinese medicament bone-knitting pill preparation, which is prepared from peach kernel, safflower, ligusticus wallichii franchet, frankincense, myrrh, corydalis, achyranthes, ground beetle, dragon blood, leech, earthworm, Chinese angelica, cooked rehmannia, pyrite, eucommia, dipsacus, drynaria, gardenia, plantago seed, lycium bark, acanthopanax, bitter orange, parsnip, angelica, dioscorea, poria, cinnamon bark, red ginseng and other precious traditional Chinese medicaments according to certain proportion; the Chinese medicament bone-knitting pellet preparation can be used for treating femoral head necrosis, in particular ischemic necrosis of femoral head and other diseases, can effectively treat the femoral head necrosis and bone fracture in clinical treatment and has the advantages of good treatment effect and no side effect.
Description
Technical field
The present invention is the Medicines technical field, relates to a kind of set a broken bone particularly the Chinese medicine bone-knitting pellet preparation and the preparation method of femur head necrosis.
Background technology
Femur head necrosis be in clinical commonly encountered diseases, coagulate difficult disease.The reason that causes femur head necrosis mainly contains two kinds, it is traumatic and atraumatic, traumatic fracture of femoral neck, hip joint traumatic dislocation, the fracture of the femoral head etc. of comprising, atraumatic comprise blood vessel embolism that hormonal, alcoholic-toxic, fat metabolic disturbance and other metabolism reasons cause and hip joint textural anomaly etc.The treatment of femur head necrosis mainly contains operative treatment and non-operative treatment two big classes at present, and operative treatment comprises artificial joint replacement, bone grafting operation, and osteotomy, the bone marrow internal decompression, Drilling, and interventional therapy etc.Therapeutic method of surgery belongs to the exploratory stage, and difficulty is big, and the expense height often causes some sequela.Non-operative treatment mainly adopts conservative medication, treatment by Chinese herbs a kind of good selection of can yet be regarded as, but there is the problem of weak curative effect in treatment by Chinese herbs at present.
Summary of the invention
Purpose of the present invention is exactly the problem at the Chinese medicine of the ideal treatment femur head necrosis of present shortage, and a kind of short treating period, eutherapeutic a kind of Chinese medicine bone-knitting pellet preparation for the treatment of femur head necrosis are provided.
The objective of the invention is to be achieved through the following technical solutions, Chinese medicine bone-knitting pellet preparation of the present invention is made up of following crude drug by weight:
Semen Persicae 1-3 part, Flos Carthami 1-3 part, Rhizoma Chuanxiong 1-3 part, Olibanum 1-3 part, Myrrha 1-3 part, Rhizoma Corydalis 1-3 part, Radix Achyranthis Bidentatae 1-3 part, eupolyphaga 1-3 part, Sanguis Draxonis 0.8-1.2 part, Hirudo 1-3 part, Pheretima 1-3 part, Radix Angelicae Sinensis 1-3 part, Radix Rehmanniae Preparata 2-4 part, Pyritum 2-3 part, Cortex Eucommiae 1-3 part, Radix Dipsaci 1-3 part, Rhizoma Drynariae 2-3 part, Fructus Gardeniae 1-3 part, Semen Plantaginis 1-3 part, Cortex Lycii 1-3 part, Cortex Acanthopancis 1-3 part, Fructus Aurantii 1-3 part, Radix Saposhnikoviae 1-3 part, Radix Angelicae Dahuricae 1-3 part, Rhizoma Dioscoreae 2-4 part, Poria 2-3 part, Cortex Cinnamomi 1-2 part, Radix Ginseng Rubra 1-3 part
Chinese medicine bone-knitting pellet preparation optimum crude drug is by weight formed:
2 parts in Semen Persicae, 2 parts on Flos Carthami, 2 parts of Rhizoma Chuanxiongs, 2 parts of Olibanums, 2 parts of Myrrhas, 2 parts of Rhizoma Corydalis, 2 parts of Radix Achyranthis Bidentataes, 2 parts of eupolyphaga, 1 part of Sanguis Draxonis, 2 parts of Hirudos, 2 parts of Pheretimas, 2 parts of Radix Angelicae Sinensis, Radix Rehmanniae Preparata 2-4 part, 2.5 parts of Pyritums, 2 parts of the Cortexs Eucommiae, 2 parts of Radix Dipsacis, 2.5 parts of Rhizoma Drynariae, 2 parts of Fructus Gardeniae, 2 parts of Semen Plantaginiss, 2 parts of Cortex Lycii, 2 parts of Cortex Acanthopanciss, 2 parts of Fructus Aurantiis, 2 parts of Radix Saposhnikoviaes, 2 parts of the Radixs Angelicae Dahuricae, 3 parts of Rhizoma Dioscoreaes, 2.5 parts in Poria, 1.5 parts of Cortex Cinnamomis, 2 parts of Radix Ginseng Rubra
Preparation method of the present invention:
Get the raw materials ready: produce standard according to preparation, choose the preparation prescription Chinese crude drug, and accurately take by weighing required weight.
Pretreatment: Semen Persicae, Semen Plantaginis are fried; Olibanum, do not have medicated vinegar to fry; The Pyritum fire is forged quench in vinegar; Rhizoma Dioscoreae, Poria parched with bran; Radix Angelicae Sinensis, eupolyphaga, Radix Achyranthis Bidentatae, Fructus Aurantii, Rhizoma Chuanxiong, Rhizoma Drynariae, Radix Dipsaci, the Radix Angelicae Dahuricae, Cortex Lycii, Cortex Acanthopancis, Radix Saposhnikoviae, Rhizoma Corydalis, the Cortex Eucommiae, Hirudo, Pheretima, Cortex Cinnamomi, Radix Ginseng Rubra are washed airing respectively; Flos Carthami, Fructus Gardeniae, Radix Rehmanniae Preparata clean respectively.
Oven dry is handled: Flos Carthami, Radix Angelicae Sinensis, Fructus Aurantii, Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Olibanum, Myrrha, Radix Saposhnikoviae are in 60 ℃ of oven dry in 2 hours; 105 ℃ of dryings of Pyritum 1 hour; All the other medical materials are in 80 ℃ of oven dry in 4 hours.
Crushing screening: Pyritum was pulverized 80 mesh sieves separately; Sanguis Draxonis was pulverized 100 mesh sieves separately, and all the other medicament mixed were pulverized 80 mesh sieves, all medicated powder is mixed sieve.
Sterilization: the medicated powder medicated powder of above mix homogeneously is put in the baking oven, after 1 hour, kept 24 hours down, carry out 3 sterilizations continuously at 20-25 ℃ with 60 ℃ of heating.
Fill: in the zero capsule-packing-quality inspection-labeling-warehouse-in.
The invention has the beneficial effects as follows: the present invention can be used for treating especially disease such as ischemic necrosis of femoral head of femur head necrosis, selected natural Chinese medicines is optimized prescription, can treat femur head necrosis and bone injury effectively in clinical treatment, has good effect, the advantage that has no side effect.
Clinical trial data:
1, selects case.Typical case's femur head necrosis case 120 examples, wherein male 82 examples, women 38 examples, year order is between 15-62 year.
2, diagnostic criteria: 1 phase: X-ray film is normal, and MRI, ECT check and can note abnormalities; 2 phases: X-ray film, MRI, ECT all can note abnormalities, but the femoral head profile is normal; 3 phases: the X-ray film inspection shows that femoral head has slightly and subsides; 4 phases: the X-ray film inspection shows that collapse of the femoral head flattens; 5 phases: the X-ray film inspection shows the hip joint gap turn narrow.
3, Therapeutic Method: take Cortex torricelliae tiliifoliae capsule of the present invention, every day 3 times, each 4-6 grain, the child reduces by half.
4, curative effect determinate standard: recovery from illness: suffer from hip pain and disappear, functional rehabilitation is normal, and the X-ray sheet shows that the femur head necrosis district repairs; Produce effects: suffer from hip pain and disappear, function is recovered substantially or is slightly limited, and the X-ray sheet shows that the femur head necrosis district obviously dwindles, and area of new bone is obvious, and femoral head has obvious reparation; Effectively: suffer from hip pain and obviously alleviate, function has improvement, but still limitation of activity, and the X-ray sheet shows that the necrotic area does not enlarge again or makes slow progress; Invalid: symptom and sign all do not have and are clearly better, and the trend of increasing the weight of is arranged.
5, clinical therapeutic efficacy.120 routine femur head necrosis cases, 1,2 phase patients take medicine 2-3 month effectively, can cure in 5-10 month; 3 phase patients take medicine and cured in 9-12 month, and 4 phase patients take medicine and cured in 14-16 month, and it cures 104 examples, 10 examples that take a turn for the better, invalid 6 examples, total effective rate 95%.
Model case
Patient: Zhang, man, 40 years old, peasant.Left knee pain discomfort appears in patient's no obvious inducement before 1 year, after gradually increase the weight of, go into my institute and go to a doctor, X-ray film shows, left side ischemic femoral head aseptic necrosis, tentative diagnosis is the left side femur head necrosis.Belong to 2 phase patients, oral Cortex torricelliae tiliifoliae capsule of the present invention, every day three times, each 6, the basic rehabilitation of patient in 12 months of taking medicine, the recovery from illness in 3 months that continues again to take medicine now can normally be worked down.
The patient: Liu so-and-so, woman, 52 years old, workman.Be diagnosed as femur head necrosis before 4 years, once in the treatment of provincial capital large hospital, the commentaries on classics of not getting better can not have been walked when coming my institute to treat, belongs to three phase patients.Oral Cortex torricelliae tiliifoliae capsule of the present invention, every day three times, each 6, the recovery from illness in 14 months of taking medicine, now normally working.
The specific embodiment
Embodiment one
Take by weighing Semen Persicae, Flos Carthami, Rhizoma Chuanxiong, Olibanum, Myrrha, Rhizoma Corydalis, Radix Achyranthis Bidentatae, eupolyphaga, Radix Angelicae Sinensis, the Cortex Eucommiae, Radix Dipsaci, Fructus Gardeniae, Semen Plantaginis, Cortex Lycii, Cortex Acanthopancis, Fructus Aurantii, Radix Saposhnikoviae, the Radix Angelicae Dahuricae, Radix Ginseng Rubra, each 2000 gram of Cortex Cinnamomi, Pyritum, Rhizoma Drynariae, each 2400 gram of Poria, Radix Rehmanniae Preparata, Pheretima, each 3000 gram of Rhizoma Dioscoreae, Sanguis Draxonis 1000 grams.Preparation according to the following steps:
Get the raw materials ready: produce standard according to preparation, choose the preparation prescription Chinese crude drug, and accurately take by weighing required weight.
Pretreatment: Semen Persicae, Semen Plantaginis are fried; Olibanum, do not have medicated vinegar to fry; The Pyritum fire is forged quench in vinegar; Rhizoma Dioscoreae, Poria parched with bran; Radix Angelicae Sinensis, eupolyphaga, Radix Achyranthis Bidentatae, Fructus Aurantii, Rhizoma Chuanxiong, Rhizoma Drynariae, Radix Dipsaci, the Radix Angelicae Dahuricae, Cortex Lycii, Cortex Acanthopancis, Radix Saposhnikoviae, Rhizoma Corydalis, the Cortex Eucommiae, Hirudo, Pheretima, Cortex Cinnamomi, Radix Ginseng Rubra are washed airing respectively; Flos Carthami, Fructus Gardeniae, Radix Rehmanniae Preparata clean respectively.
Oven dry is handled: Flos Carthami, Radix Angelicae Sinensis, Fructus Aurantii, Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Olibanum, Myrrha, Radix Saposhnikoviae are in 60 ℃ of oven dry in 2 hours; 105 ℃ of Pyritums 1 hour; All the other medical materials are in 80 ℃ of oven dry in 4 hours.
Crushing screening: Pyritum was pulverized 80 mesh sieves separately; Sanguis Draxonis was pulverized 100 mesh sieves separately, and all the other medicament mixed were pulverized 80 mesh sieves, all medicated powder is mixed sieve.
Sterilization: the medicated powder medicated powder of above mix homogeneously is put in the baking oven, after 1 hour, kept 24 hours down, carry out 3 sterilizations continuously at 20-25 ℃ with 60 ℃ of heating.
Fill: in the zero capsule-packing-quality inspection-labeling-warehouse-in
Embodiment two
Take by weighing Semen Persicae, Flos Carthami, Rhizoma Chuanxiong, Olibanum, Myrrha, Rhizoma Corydalis, Radix Achyranthis Bidentatae, eupolyphaga, Radix Angelicae Sinensis, the Cortex Eucommiae, Radix Dipsaci, Fructus Gardeniae, Semen Plantaginis, each 1400 gram of Cortex Lycii, Cortex Acanthopancis, Fructus Aurantii, Radix Saposhnikoviae, the Radix Angelicae Dahuricae, Radix Ginseng Rubra, each 1600 gram of Cortex Cinnamomi, Pyritum 3000 grams, Rhizoma Drynariae, each 2200 gram of Poria, Radix Rehmanniae Preparata, each 2800 gram of Pheretima, Rhizoma Dioscoreae 3200 grams, Sanguis Draxonis 900 grams.Preparation method is with embodiment one.
Claims (2)
1. a Chinese medicine bone-knitting pellet preparation is characterized in that being made by following crude drug by weight: Semen Persicae 1-3 part, Flos Carthami 1-3 part, Rhizoma Chuanxiong 1-3 part, Olibanum 1-3 part, Myrrha 1-3 part, Rhizoma Corydalis 1-3 part, Radix Achyranthis Bidentatae 1-3 part, eupolyphaga 1-3 part, Sanguis Draxonis 0.8-12 part, Hirudo 1-3 part, Pheretima 1-3 part, Radix Angelicae Sinensis 1-3 part, Radix Rehmanniae Preparata 2-4 part, Pyritum 2-3 part, Cortex Eucommiae 1-3 part, Radix Dipsaci 1-3 part, Rhizoma Drynariae 2-3 part, Fructus Gardeniae 1-3 part, Semen Plantaginis 1-3 part, Cortex Lycii 1-3 part, Cortex Acanthopancis 1-3 part, Fructus Aurantii 1-3 part, Radix Saposhnikoviae 1-3 part, Radix Angelicae Dahuricae 1-3 part, Rhizoma Dioscoreae 2-4 part, Poria 2-3 part, Cortex Cinnamomi 1-2 part, Radix Ginseng Rubra 1-3 part; Its preparation method is for getting the raw materials ready: produce standard according to preparation, choose the preparation prescription Chinese crude drug, and accurately take by weighing required weight; Pretreatment: Semen Persicae, Semen Plantaginis are fried; Olibanum, do not have medicated vinegar to fry; The Pyritum fire is forged quench in vinegar; Rhizoma Dioscoreae, Poria parched with bran; Radix Angelicae Sinensis, eupolyphaga, Radix Achyranthis Bidentatae, Fructus Aurantii, Rhizoma Chuanxiong, Rhizoma Drynariae, Radix Dipsaci, the Radix Angelicae Dahuricae, Cortex Lycii, Cortex Acanthopancis, Radix Saposhnikoviae, Rhizoma Corydalis, the Cortex Eucommiae, Hirudo, Pheretima, Cortex Cinnamomi, Radix Ginseng Rubra are washed airing respectively; Flos Carthami, Fructus Gardeniae, Radix Rehmanniae Preparata clean respectively; Oven dry is handled: Flos Carthami, Radix Angelicae Sinensis, Fructus Aurantii, Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Olibanum, Myrrha, Radix Saposhnikoviae are in 60 ℃ of oven dry in 2 hours; 105 ℃ of dryings of Pyritum 1 hour; All the other medical materials are in 80 ℃ of oven dry in 4 hours; Crushing screening: Pyritum was pulverized 80 mesh sieves separately; Sanguis Draxonis was pulverized 100 mesh sieves separately, and all the other medicament mixed were pulverized 80 mesh sieves, all medicated powder is mixed sieve; Sterilization: the medicated powder of above mix homogeneously is put in the baking oven, and 60 ℃ of heating kept 24 hours down at 20-25 ℃ after 1 hour, carried out 3 sterilizations continuously; Fill: in the zero capsule-packing-quality inspection-labeling-warehouse-in.
2. a kind of Chinese medicine bone-knitting pellet preparation according to claim 1 is characterized in that this Chinese medicine bone-knitting pellet preparation made by following crude drug by weight: 2 parts in Semen Persicae, 2 parts on Flos Carthami, 2 parts of Rhizoma Chuanxiongs, 2 parts of Olibanums, 2 parts of Myrrhas, 2 parts of Rhizoma Corydalis, 2 parts of Radix Achyranthis Bidentataes, 2 parts of eupolyphaga, 1 part of Sanguis Draxonis, 2 parts of Hirudos, 2 parts of Pheretimas, 2 parts of Radix Angelicae Sinensis, Radix Rehmanniae Preparata 2-4 part, 2.5 parts of Pyritums, 2 parts of the Cortexs Eucommiae, 2 parts of Radix Dipsacis, 2.5 parts of Rhizoma Drynariae, 2 parts of Fructus Gardeniae, 2 parts of Semen Plantaginiss, 2 parts of Cortex Lycii, 2 parts of Cortex Acanthopanciss, 2 parts of Fructus Aurantiis, 2 parts of Radix Saposhnikoviaes, 2 parts of the Radixs Angelicae Dahuricae, 3 parts of Rhizoma Dioscoreaes, 2.5 parts in Poria, 1.5 parts of Cortex Cinnamomis, 2 parts of Radix Ginseng Rubra.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2008100170416A CN101607022B (en) | 2008-06-16 | 2008-06-16 | Chinese medicament bone-knitting pellet preparation |
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| CN2008100170416A CN101607022B (en) | 2008-06-16 | 2008-06-16 | Chinese medicament bone-knitting pellet preparation |
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| CN101607022B true CN101607022B (en) | 2011-04-20 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102813778B (en) * | 2012-07-30 | 2015-09-09 | 汤杰杰 | A kind of oral Chinese medicine for the treatment of of arthritis |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102091238B (en) * | 2010-12-06 | 2012-05-23 | 郭保岩 | Traditional Chinese medicinal composition for treating femoral head necrosis |
| CN102512526B (en) * | 2011-12-15 | 2014-01-15 | 天长市中医院 | Medicine for treating early bone injury and soft tissue injury |
| CN103784846A (en) * | 2013-12-30 | 2014-05-14 | 王波兰 | Medicinal preparation for treating femoral neck fracture |
| CN110141636A (en) * | 2019-06-17 | 2019-08-20 | 烟台了神医疗器械有限公司 | A kind of Chinese materia medica preparation and preparation method thereof for treating caput femoris necrosis |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1333025A (en) * | 2000-07-11 | 2002-01-30 | 李鹏 | Medicine for treating bone injury |
| CN1362256A (en) * | 2001-12-26 | 2002-08-07 | 邹明义 | Osteological Chinese medicine prepn. |
| CN1429616A (en) * | 2003-02-09 | 2003-07-16 | 卫永生 | New preparation of compound Chinese medicine for treating osteoarthritis and its preparation method |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102813778B (en) * | 2012-07-30 | 2015-09-09 | 汤杰杰 | A kind of oral Chinese medicine for the treatment of of arthritis |
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| CN101607022A (en) | 2009-12-23 |
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