CN105395867A - Traditional Chinese medicine bone-joining elixir for treating fracture and preparation method of traditional Chinese medicine bone-joining elixir - Google Patents

Traditional Chinese medicine bone-joining elixir for treating fracture and preparation method of traditional Chinese medicine bone-joining elixir Download PDF

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Publication number
CN105395867A
CN105395867A CN201510880157.2A CN201510880157A CN105395867A CN 105395867 A CN105395867 A CN 105395867A CN 201510880157 A CN201510880157 A CN 201510880157A CN 105395867 A CN105395867 A CN 105395867A
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parts
folium
chinese medicine
traditional chinese
ramulus
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潘俊博
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Yi'nan Panfeng Orthopaedics Hospital
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Yi'nan Panfeng Orthopaedics Hospital
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13Coniferophyta (gymnosperms)
    • A61K36/14Cupressaceae (Cypress family), e.g. juniper or cypress
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/27Asclepiadaceae (Milkweed family), e.g. hoya
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/324Boswellia, e.g. frankincense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/328Commiphora, e.g. mecca myrrh or balm of Gilead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/40Cornaceae (Dogwood family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/67Piperaceae (Pepper family), e.g. Jamaican pepper or kava
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)

Abstract

The invention discloses traditional Chinese medicine bone-joining elixir for treating fracture and a preparation method of the traditional Chinese medicine bone-joining elixir, belonging to the technical field of traditional Chinese medicines. Aiming at the causes of the fracture, the traditional Chinese medicine bone-joining elixir selects the following traditional Chinese medicinal materials: branches, leaves or root of raphiolepis indica, chachi citrus leaves, cudrania tricuspidata leaves, cudrania tricuspidata fruits, oriental mistletoe, cupressin, centranthera cochinchinensis, root of littleleaf dogwood, psychotria serpens, strawberry with knotted roots, Panax pseudo-ginseng Wsll. Var, jasminum lanceolarium, whole grass of biondia henryi, holly leaves, herb of digitateleaf eria, frankincense, myrrh, all-grass of irisleaf oberonia, and stem and leaf of wallich pepper. The traditional Chinese medicine bone-joining elixir is prepared into a capsule, and the clinical test proves that the capsule has significant curative effects.

Description

A kind of Chinese medicine synthetism DANJI preparation method for the treatment of fracture
Technical field
The present invention relates to a kind of Chinese medicine composition, particularly relate to a kind of Chinese medicine synthetism DANJI preparation method for the treatment of the particularly femur head necrosis of fracturing.
Background technology
Femur head necrosis be clinical in commonly encountered diseases, solidifying difficult disease.The reason of femur head necrosis is caused to mainly contain two kinds, i.e. traumatic and atraumatic, traumaticly comprise fracture of femoral neck, hip joint traumatic dislocation, fracture of the femoral head etc., atraumatic comprises the blood vessel embolism and hip joint textural anomaly etc. that hormonal, alcoholic-toxic, fat metabolic disturbance and other metabolism reasons cause.The treatment of femur head necrosis, mainly contain operative treatment and the large class of non-operative treatment two at present, operative treatment comprises artificial joint replacement, bone grafting operation, osteotomy, bone marrow internal decompression, Drilling, and interventional therapy etc.Therapeutic method of surgery belongs to the exploratory stage, and difficulty is large, costly, often causes some sequela.Non-operative treatment mainly adopts conservative medication, and treatment by Chinese herbs be can yet be regarded as a kind of good selection, but treatment by Chinese herbs at present exists the problem of weak curative effect.
Summary of the invention
Object of the present invention is exactly the problem for the Chinese medicine lacking desirable treatment femur head necrosis at present, provides the Chinese medicine Cortex torricelliae tiliifoliae of a kind of short treating period, eutherapeutic treatment femur head necrosis.
The object of the invention is to be achieved through the following technical solutions, this Chinese medicine Cortex torricelliae tiliifoliae is made up of the Chinese medicine of following weight portion: Ramulus et Folium Raphiolepis indicae 2-4 part, Citrus chachiensis Hort. (C. Suavissima Tanaka) 2-4 part, Ramulus et Folium Cudraniae tricuspidatae 2-4 part, Fructus Cudraniae tricuspidatae 2-4 part, Ramulus et Folium visci ovalifolii 2-4 part, Resina Cupressi 2-4 part, Herba Centrantherae Cochinchinensis 1-2 part, Radix Corni Paucinervis 1-2 part, Ramulus et Folium Psychotriae Serpentis 1-2 part, Fragaria filipendula Hemsl. 1-2 part, Rhizoma panacis majoris 1-2 part, Radix seu Caulis Jasmini lanceolarii 1-2 part, Herba Biondiae henryi 1-3 part, Folium Ilicis Cornutae 1-3 part, Herba Eriae Panneae 1-3 part, Olibanum 1-3 part, Myrrha 1-3 part, Herba Oberoniae iridifoliae 1-3 part, Caulis et Folium piperis 1-3 part.
Preferred: Ramulus et Folium Raphiolepis indicae 3 parts, Citrus chachiensis Hort. (C. Suavissima Tanaka) 3 parts, Ramulus et Folium Cudraniae tricuspidatae 3 parts, Fructus Cudraniae tricuspidatae 3 parts, Ramulus et Folium visci ovalifolii 3 parts, Resina Cupressi 3 parts, Herba Centrantherae Cochinchinensis 1.5 parts, Radix Corni Paucinervis 1.5 parts, Ramulus et Folium Psychotriae Serpentis 1.5 parts, Fragaria filipendula Hemsl. 1.5 parts, Rhizoma panacis majoris 1.5 parts, Radix seu Caulis Jasmini lanceolarii 1.5 parts, Herba Biondiae henryi 2 parts, Folium Ilicis Cornutae 2 parts, Herba Eriae Panneae 2 parts, Olibanum 2 parts, Myrrha 2 parts, Herba Oberoniae iridifoliae 2 parts, Caulis et Folium piperis 2 parts.
Preparation method of the present invention:
Get the raw materials ready: by the neat each Chinese crude drug of reprovision.
Pretreatment: Olibanum, do not have medicated vinegar to fry; Resina Cupressi cleans; All the other Chinese herbal medicine water is cleaned and is dried.
Drying and processing: each Chinese herbal medicine is dried in 60 DEG C.
Pulverize and sieve: after each Chinese herbal medicine was pulverized 80 mesh sieves respectively, then by all medicated powder mix homogeneously.
Sterilizing: put in baking oven by the medicated powder of above mix homogeneously, after 1 hour with 60 DEG C of heating, keeps 20 hours, carries out 3 sterilizings continuously at 20-25 DEG C.
Fill: in zero capsule-packaging-quality inspection-labeling-warehouse-in.
The invention has the beneficial effects as follows: the present invention can be used for the treatment femur head necrosis especially disease such as ischemic necrosis of femoral head, selected natural Chinese medicines, optimizes prescription, can effectively treat femur head necrosis and bone injury in clinical treatment, there is good effect, the advantage had no side effect.
Clinical trial data:
1, case is selected.Typical case's femur head necrosis case 100 example, wherein man 50 example, female 50 example, the age is between 17-68 years old.
2, diagnostic criteria: 1 phase: X-ray film is normal, MRI, ECT check and can note abnormalities; 2 phases: X-ray film, MRI, ECT all can note abnormalities, but femoral head shape is normal; 3 phases: X-ray film inspection display femoral head has mild collapse; 4 phases: X-ray film inspection display collapse of the femoral head flattens; 5 phases: X-ray film inspection display hip joint space narrows.
3, Therapeutic Method: take Jiegudan Capsules of the present invention, every day 3 times, each 2-4 grain, child reduces by half.
4, curative effect determinate standard: recovery from illness: suffer from hip pain and disappear, functional rehabilitation is normal, and X-ray shows that femur head necrosis district repairs; Effective: suffer from hip pain and disappear, function is recovered or slightly limited substantially, and X-ray shows that femur head necrosis district obviously reduces, and area of new bone is obvious, and femoral head has obvious reparation; Effective: suffer from hip pain and obviously alleviate, function is improved, but still limitation of activity, X-ray shows that necrotic area does not expand again or makes slow progress; Invalid: symptom and sign all without being clearly better, and have and increase the weight of trend.
5, clinical therapeutic efficacy.100 routine femur head necrosis cases, 1,2 phase patient consumes 2 months are effective, within 4-6 month, can cure; Within 3 phase patient consumes 6-10 months, cure, within 4 phase patient consumes 10-14 months, cure, it cures 94 examples, and take a turn for the better 3 examples, invalid 3 examples, total effective rate 97%.
Model case
Patient: Zhang, man, 43 years old, peasant.Without obvious inducement, patient occurred that left knee pain was uncomfortable before 1 year, after gradually increase the weight of, enter me and institute go to a doctor, X-ray film shows, left femoral head ischemic aseptic necrosis, and tentative diagnosis is that left femoral head is downright bad.Belong to 2 phase patients, oral Jiegudan Capsules of the present invention, every day three times, each 3, the basic rehabilitation of patient in 4 months of taking medicine, continues again recovery from illness in 2 months of taking medicine, now can normally work down.
Patient: Liu so-and-so, female, 48 years old, workman.Be diagnosed as femur head necrosis before 4 years, once in the treatment of provincial capital large hospital, have no improvement, can not walk when carrying out my institute's treatment, belong to three phase patients.Oral Jiegudan Capsules of the present invention, every day three times, each 3, recovery from illness in 6 months of taking medicine, now normally goes to work.
Detailed description of the invention
Embodiment one: take Ramulus et Folium Raphiolepis indicae, Citrus chachiensis Hort. (C. Suavissima Tanaka), Ramulus et Folium Cudraniae tricuspidatae, Fructus Cudraniae tricuspidatae, Ramulus et Folium visci ovalifolii, each 2000 grams of Resina Cupressi, Herba Centrantherae Cochinchinensis, Radix Corni Paucinervis, Ramulus et Folium Psychotriae Serpentis, Fragaria filipendula Hemsl., Rhizoma panacis majoris, Radix seu Caulis Jasmini lanceolarii, Herba Biondiae henryi, Folium Ilicis Cornutae, Herba Eriae Panneae, Olibanum, Myrrha, Herba Oberoniae iridifoliae, each 1000 grams of Caulis et Folium piperis.
Get the raw materials ready: produce standard according to preparation, choose preparation prescription Chinese crude drug, and accurately take required weight.
Pretreatment: Olibanum, do not have medicated vinegar to fry; Resina Cupressi cleans; All the other each Chinese herbal medicine washing airings.
Drying and processing: the Chinese herbal medicine chosen above is dried in 60 DEG C for 2 hours.
Pulverize and sieve: after each Chinese herbal medicine was pulverized 80 mesh sieves respectively, then by all medicated powder mix homogeneously.
Sterilizing: put in baking oven by the medicated powder of above mix homogeneously, after 1 hour with 60 DEG C of heating, keeps 20 hours, carries out 3 sterilizings continuously at 20-25 DEG C.
Fill: in zero capsule-packaging-quality inspection-labeling-warehouse-in.
Embodiment two: take Ramulus et Folium Raphiolepis indicae, Citrus chachiensis Hort. (C. Suavissima Tanaka), Ramulus et Folium Cudraniae tricuspidatae, Fructus Cudraniae tricuspidatae, Ramulus et Folium visci ovalifolii, Resina Cupressi 3000 grams; Herba Centrantherae Cochinchinensis, Radix Corni Paucinervis, Ramulus et Folium Psychotriae Serpentis, Fragaria filipendula Hemsl., Rhizoma panacis majoris, Radix seu Caulis Jasmini lanceolarii 1500 grams; Herba Biondiae henryi, Folium Ilicis Cornutae, Herba Eriae Panneae, Olibanum, Myrrha, Herba Oberoniae iridifoliae, Caulis et Folium piperis 2000 grams, preparation method is with embodiment one
Embodiment three: take Ramulus et Folium Raphiolepis indicae, Citrus chachiensis Hort. (C. Suavissima Tanaka), Ramulus et Folium Cudraniae tricuspidatae, Fructus Cudraniae tricuspidatae, Ramulus et Folium visci ovalifolii, Resina Cupressi 4000 grams; Herba Centrantherae Cochinchinensis, Radix Corni Paucinervis, Ramulus et Folium Psychotriae Serpentis, Fragaria filipendula Hemsl., Rhizoma panacis majoris, Radix seu Caulis Jasmini lanceolarii 2000 grams; Herba Biondiae henryi, Folium Ilicis Cornutae, Herba Eriae Panneae, Olibanum, Myrrha, Herba Oberoniae iridifoliae, Caulis et Folium piperis 3000 grams, preparation method is with embodiment one.

Claims (2)

1. treat a Chinese medicine Cortex torricelliae tiliifoliae for fracture, it is characterized in that this Chinese medicine Cortex torricelliae tiliifoliae is made up of the Chinese medicine of following weight portion: Ramulus et Folium Raphiolepis indicae 2-4 part, Citrus chachiensis Hort. (C. Suavissima Tanaka) 2-4 part, Ramulus et Folium Cudraniae tricuspidatae 2-4 part, Fructus Cudraniae tricuspidatae 2-4 part, Ramulus et Folium visci ovalifolii 2-4 part, Resina Cupressi 2-4 part, Herba Centrantherae Cochinchinensis 1-2 part, Radix Corni Paucinervis 1-2 part, Ramulus et Folium Psychotriae Serpentis 1-2 part, Fragaria filipendula Hemsl. 1-2 part, Rhizoma panacis majoris 1-2 part, Radix seu Caulis Jasmini lanceolarii 1-2 part, Herba Biondiae henryi 1-3 part, Folium Ilicis Cornutae 1-3 part, Herba Eriae Panneae 1-3 part, Olibanum 1-3 part, Myrrha 1-3 part, Herba Oberoniae iridifoliae 1-3 part, Caulis et Folium piperis 1-3 part.
2. a kind of Chinese medicine Cortex torricelliae tiliifoliae for the treatment of fracture as claimed in claim 1, is characterized in that this Chinese medicine Cortex torricelliae tiliifoliae is made up of the Chinese medicine of following weight portion: Ramulus et Folium Raphiolepis indicae 3 parts, Citrus chachiensis Hort. (C. Suavissima Tanaka) 3 parts, Ramulus et Folium Cudraniae tricuspidatae 3 parts, Fructus Cudraniae tricuspidatae 3 parts, Ramulus et Folium visci ovalifolii 3 parts, Resina Cupressi 3 parts, Herba Centrantherae Cochinchinensis 1.5 parts, Radix Corni Paucinervis 1.5 parts, Ramulus et Folium Psychotriae Serpentis 1.5 parts, Fragaria filipendula Hemsl. 1.5 parts, Rhizoma panacis majoris 1.5 parts, Radix seu Caulis Jasmini lanceolarii 1.5 parts, Herba Biondiae henryi 2 parts, Folium Ilicis Cornutae 2 parts, Herba Eriae Panneae 2 parts, Olibanum 2 parts, Myrrha 2 parts, Herba Oberoniae iridifoliae 2 parts, Caulis et Folium piperis 2 parts.
CN201510880157.2A 2015-12-06 2015-12-06 Traditional Chinese medicine bone-joining elixir for treating fracture and preparation method of traditional Chinese medicine bone-joining elixir Pending CN105395867A (en)

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Publication number Priority date Publication date Assignee Title
CN105998333A (en) * 2016-06-27 2016-10-12 张瑾 Traditional Chinese medicine capsules for treating rib fracture and preparing method
CN108743804A (en) * 2018-08-10 2018-11-06 徐丽 Treat the Chinese medicine of fracture

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CN102488821A (en) * 2011-12-16 2012-06-13 王疆宏 Traditional Chinese medicine composition for treating bone fracture and preparation method thereof
CN103623249A (en) * 2013-12-05 2014-03-12 韩友群 Traditional Chinese medicine oral preparation for treating orthopedic disorders and preparation method thereof

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105998333A (en) * 2016-06-27 2016-10-12 张瑾 Traditional Chinese medicine capsules for treating rib fracture and preparing method
CN108743804A (en) * 2018-08-10 2018-11-06 徐丽 Treat the Chinese medicine of fracture

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Application publication date: 20160316