CN112138111A - Traditional Chinese medicine for treating femoral head necrosis and preparation method thereof - Google Patents

Traditional Chinese medicine for treating femoral head necrosis and preparation method thereof Download PDF

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CN112138111A
CN112138111A CN202011181681.8A CN202011181681A CN112138111A CN 112138111 A CN112138111 A CN 112138111A CN 202011181681 A CN202011181681 A CN 202011181681A CN 112138111 A CN112138111 A CN 112138111A
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femoral head
traditional chinese
chinese medicine
head necrosis
treating femoral
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黄宪程
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Abstract

The invention discloses a traditional Chinese medicine for treating femoral head necrosis and a preparation method thereof, belonging to the technical field of traditional Chinese medicines. The traditional Chinese medicine for treating femoral head necrosis is prepared from the following raw materials in parts by weight: 18g-22g of water hyacinth, 12g-18g of angelica sinensis, 12g-18g of achyranthes bidentata, 12g-18g of semipocurrent, 12g-18g of boenninghausenia herb, 12g-18g of rhubard, 12g-18g of cibotium barometz, 12g-18g of rhubard, 12g-18g of gynostemma pentaphylla and 12g-18g of corydalis tuber. The invention also discloses a preparation method of the traditional Chinese medicine for treating femoral head necrosis. The traditional Chinese medicine for treating femoral head necrosis is prepared from multiple traditional Chinese medicines, has reasonable composition and proper compatibility, fully releases the active ingredients of each component, has the effects of activating blood, relieving pain, removing blood stasis, relieving swelling, removing putrefaction and promoting tissue regeneration, and is used for treating femoral head necrosis.

Description

Traditional Chinese medicine for treating femoral head necrosis and preparation method thereof
Technical Field
The invention relates to a traditional Chinese medicine for treating femoral head necrosis and a preparation method thereof, belonging to the technical field of traditional Chinese medicines.
Background
Femoral head necrosis is one of common osteoarthropathy, and the main pathology is femoral head bone ischemia caused by the obstruction of femoral head blood circulation and the damage, which is often called ischemic necrosis of femoral head or aseptic necrosis of femoral head. If early femoral head necrosis cannot be effectively treated in time, the femoral head can collapse, the joint space becomes narrow, and finally osteoarthritis is caused. More and more studies have shown that the pathogenesis of avascular necrosis of the femoral head is extremely complex and cannot be explained with a single theory, but it should be considered as the same final manifestation of different diseases with multifactorial, multistage onset.
At present, the means for treating femoral head necrosis comprise operation treatment and traditional Chinese medicine treatment, and the operation treatment comprises core decompression, vascular bundle implantation, bone grafting, osteotomy, hip arthroplasty, porous tantalum rod treatment, bone marrow mesenchymal stem cell treatment and the like. But the operation treatment has great harm to human body and the curative effect is not ensured; and the operation treatment has certain risks and is easy to relapse after the operation. The traditional treatment means such as massage, traction, acupuncture, physiotherapy, massage and the like have small adverse reactions, but the long-term curative effect is difficult to determine. The western medicine adopts anti-inflammatory analgesic drugs mostly, but has obvious adverse reaction, thereby treating both symptoms and root causes, and having low curative effect, great side effect and strong dependence.
The Chinese medicine considers that the cause of the disease is external cause and internal cause, and the interaction of the external cause and the internal cause can lead to imbalance of yin and yang and imbalance of qi and blood, which are also called as "bi-Pisi", "bi-arthralgia" and "bone atrophy". The femoral head necrosis has a complex pathological process, if the femoral head necrosis cannot be timely and effectively treated in an early stage, the femoral head is collapsed, the joint gap is narrowed, and finally osteoarthritis is caused, so that the hip joint of a patient is disabled to cause paralysis. The existing traditional Chinese medicine for treating femoral head necrosis has a certain inhibiting effect on an affected part at the initial stage of use, can relieve part of pain of a patient, but has a non-ideal final treatment effect, can only relieve the pain and cannot radically cure the disease.
Therefore, a traditional Chinese medicine for treating femoral head necrosis and a preparation method thereof are urgently needed to solve the defects of the prior art.
Disclosure of Invention
The invention aims at providing a traditional Chinese medicine for treating femoral head necrosis. The traditional Chinese medicine for treating femoral head necrosis is prepared from multiple traditional Chinese medicines, has reasonable composition and proper compatibility, fully releases the active ingredients of each component, has the effects of activating blood, relieving pain, removing blood stasis, relieving swelling, removing putrefaction and promoting tissue regeneration, and is used for treating femoral head necrosis.
The technical scheme for solving the technical problems is as follows: a traditional Chinese medicine for treating femoral head necrosis is prepared from the following raw materials by weight: 18g-22g of water hyacinth, 12g-18g of angelica sinensis, 12g-18g of achyranthes bidentata, 12g-18g of semipocurrent, 12g-18g of boenninghausenia herb, 12g-18g of rhubard, 12g-18g of cibotium barometz, 12g-18g of rhubard, 12g-18g of gynostemma pentaphylla and 12g-18g of corydalis tuber.
The brief introduction of the raw materials adopted by the traditional Chinese medicine for treating femoral head necrosis of the invention is as follows:
the water lily is pungent, bitter and neutral in flavor, enters lung, spleen, liver and kidney meridians, and has the effects of activating blood circulation, dissipating blood stasis, removing rheumatism and dredging joints.
The angelica sinensis and rattan is bitter and astringent in taste and warm in nature, enters liver and kidney meridians, and has the effects of enriching blood, activating blood and strengthening waist and knees.
Achyranthes root, radix Achyranthis bidentatae, bitter and sour in taste, neutral in nature, enters liver and kidney meridians, and has the effects of activating blood and stimulating menstrual flow, inducing diuresis and treating stranguria, and clearing away heat and toxic materials.
Semipouch wind has the effects of dispelling wind and removing dampness, relaxing muscles and tendons, promoting blood circulation, and relieving swelling and pain.
The cauda edulis is sweet in taste, slightly bitter and neutral in nature, enters liver and lung channels, and has the effects of expelling wind-damp, dredging channels and collaterals, eliminating phlegm and relieving cough.
The square diamond is slightly sour and astringent in taste and neutral in nature, and has the effects of dispelling wind and removing dampness, relaxing tendons and activating collaterals, and removing blood stasis and promoting tissue regeneration.
Cibotium barometz, bitter and sweet in taste, warm in nature, enters liver and kidney meridians, and has the effects of dispelling wind-damp, tonifying liver and kidney, and strengthening waist and knees.
Baizui, pungent in flavor and warm in nature, has the effects of dispelling wind and removing dampness, eliminating stasis and swelling, and promoting qi circulation and relieving pain.
Gynostemma pentaphylla is slightly sweet in taste and cool in nature, enters lung, spleen and kidney meridians, and has the effects of tonifying qi and spleen, reducing phlegm and relieving cough, and clearing heat and removing toxicity.
Corydalis tuber, pungent and bitter in flavor and warm in nature, enters liver, stomach, heart, lung and spleen channels and has the effects of promoting blood circulation, removing blood stasis, regulating qi and relieving pain.
The raw materials play a single role, and simultaneously play the effects of promoting blood circulation, relieving pain, removing blood stasis, relieving swelling, removing putrefaction and promoting tissue regeneration, and are used for treating femoral head necrosis.
The traditional Chinese medicine for treating femoral head necrosis has the beneficial effects that:
(1) the traditional Chinese medicine for treating femoral head necrosis is prepared from multiple traditional Chinese medicines, has reasonable composition and proper compatibility, fully releases the active ingredients of each component, has the effects of activating blood, relieving pain, removing blood stasis, relieving swelling, removing putrefaction and promoting tissue regeneration, and is used for treating femoral head necrosis.
(2) The traditional Chinese medicine for treating femoral head necrosis has the advantages of no toxic or side effect, quick and lasting effect and safe and reliable use.
On the basis of the technical scheme, the invention can be further improved as follows.
Further, the feed is prepared from the following raw materials in parts by weight: 18g of water hyacinth, 18g of angelica sinensis, 12g of achyranthes bidentata, 18g of semipowde, 12g of cauda equisetifolia, 18g of tetragonal diamond, 12g of rhizoma cibotii, 18g of white diamond, 12g of gynostemma pentaphyllum and 18g of corydalis tuber.
The adoption of the further beneficial effects is as follows: the traditional Chinese medicine for treating femoral head necrosis obtained by adopting the raw materials in the proportion has more obvious drug effect.
Further, the feed is prepared from the following raw materials in parts by weight: 20g of water hyacinth, 15g of Chinese angelica stem, 15g of achyranthes root, 15g of semiaquilegia root, 15g of cowherb root, 15g of tetragonal diamond, 15g of cibot rhizome, 15g of white diamond, 15g of fiveleaf gynostemma herb and 15g of corydalis tuber.
The adoption of the further beneficial effects is as follows: the traditional Chinese medicine for treating femoral head necrosis obtained by adopting the raw materials in the proportion has more obvious drug effect.
Further, the feed is prepared from the following raw materials in parts by weight: 22g of water hyacinth, 12g of angelica sinensis, 18g of achyranthes bidentata, 12g of semipoetic stem, 18g of caudate dock root, 12g of tetragonal diamond, 18g of rhizoma cibotii, 12g of white diamond, 18g of gynostemma pentaphylla and 12g of corydalis tuber.
The adoption of the further beneficial effects is as follows: the traditional Chinese medicine for treating femoral head necrosis obtained by adopting the raw materials in the proportion has more obvious drug effect.
The second purpose of the invention is to provide a preparation method of the traditional Chinese medicine for treating femoral head necrosis. The preparation method of the traditional Chinese medicine for treating femoral head necrosis is simple, easy to operate, wide in medicine source, low in cost, wide in market prospect and suitable for popularization and application.
The technical scheme for solving the technical problems is as follows: a preparation method of a traditional Chinese medicine for treating femoral head necrosis comprises the following steps:
respectively weighing the following raw materials by weight: 18g-22g of water hyacinth, 12g-18g of angelica sinensis, 12g-18g of achyranthes bidentata, 12g-18g of semipocurrent, 12g-18g of boehtail, 12g-18g of rhubard, 12g-18g of cibotium barometz, 12g-18g of rhubard, 12g-18g of gynostemma pentaphylla and 12g-18g of corydalis tuber, and the traditional Chinese medicine for treating femoral head necrosis is obtained after the raw materials are respectively crushed, sieved and packaged.
The preparation method of the traditional Chinese medicine for treating femoral head necrosis has the beneficial effects that:
the preparation method of the traditional Chinese medicine for treating femoral head necrosis is simple, easy to operate, wide in medicine source, low in cost, wide in market prospect and suitable for popularization and application.
The application method of the traditional Chinese medicine for treating femoral head necrosis comprises the following steps:
weighing the raw materials at the ratio of 1 dose, decocting for 2-3 times per day, 1 dose per day, 10 days for 1 course, 3-5 courses, and avoiding pungent food during administration.
On the basis of the technical scheme, the invention can be further improved as follows.
Further, the weight of the raw materials is as follows: 18g of water hyacinth, 18g of angelica sinensis, 12g of achyranthes bidentata, 18g of semipowde, 12g of cauda equisetifolia, 18g of tetragonal diamond, 12g of rhizoma cibotii, 18g of white diamond, 12g of gynostemma pentaphyllum and 18g of corydalis tuber.
The adoption of the further beneficial effects is as follows: the traditional Chinese medicine for treating femoral head necrosis obtained by adopting the raw materials in the proportion has more obvious drug effect.
Further, the weight of the raw materials is as follows: 20g of water hyacinth, 15g of Chinese angelica stem, 15g of achyranthes root, 15g of semiaquilegia root, 15g of cowherb root, 15g of tetragonal diamond, 15g of cibot rhizome, 15g of white diamond, 15g of fiveleaf gynostemma herb and 15g of corydalis tuber.
The adoption of the further beneficial effects is as follows: the traditional Chinese medicine for treating femoral head necrosis obtained by adopting the raw materials in the proportion has more obvious drug effect.
Further, the weight of the raw materials is as follows: 22g of water hyacinth, 12g of angelica sinensis, 18g of achyranthes bidentata, 12g of semipoetic stem, 18g of caudate dock root, 12g of tetragonal diamond, 18g of rhizoma cibotii, 12g of white diamond, 18g of gynostemma pentaphylla and 12g of corydalis tuber.
The adoption of the further beneficial effects is as follows: the traditional Chinese medicine for treating femoral head necrosis obtained by adopting the raw materials in the proportion has more obvious drug effect.
Further, the aperture of the sieve is 100 meshes.
The adoption of the further beneficial effects is as follows: the screened aperture is 100 meshes, so that the beneficial components of the raw materials in the traditional Chinese medicine for treating femoral head necrosis are easier to dissolve out, and the medicine effect is better.
Detailed Description
The principles and features of this invention are described below in conjunction with specific embodiments, which are set forth merely to illustrate the invention and are not intended to limit the scope of the invention.
Example 1:
the traditional Chinese medicine for treating femoral head necrosis is prepared from the following raw materials in parts by weight: 18g of water hyacinth, 18g of angelica sinensis, 12g of achyranthes bidentata, 18g of semipowde, 12g of cauda equisetifolia, 18g of tetragonal diamond, 12g of rhizoma cibotii, 18g of white diamond, 12g of gynostemma pentaphyllum and 18g of corydalis tuber.
The preparation method of the traditional Chinese medicine for treating femoral head necrosis comprises the following steps:
respectively weighing the following raw materials by weight: 18g of water hyacinth, 18g of Chinese angelica stem, 12g of achyranthes root, 18g of semiaquilegia root, 12g of cowherb root, 18g of tetragonal diamond, 12g of rhizoma cibotii, 18g of white diamond, 12g of gynostemma pentaphyllum and 18g of corydalis tuber are poured into the raw materials, respectively crushed, sieved by a 100-mesh sieve and packaged to obtain the traditional Chinese medicine for treating femoral head necrosis.
Example 2:
the traditional Chinese medicine for treating femoral head necrosis is prepared from the following raw materials in parts by weight: 20g of water hyacinth, 15g of Chinese angelica stem, 15g of achyranthes root, 15g of semiaquilegia root, 15g of cowherb root, 15g of tetragonal diamond, 15g of cibot rhizome, 15g of white diamond, 15g of fiveleaf gynostemma herb and 15g of corydalis tuber.
The preparation method of the traditional Chinese medicine for treating femoral head necrosis comprises the following steps:
respectively weighing the following raw materials by weight: 20g of water hyacinth, 15g of Chinese angelica stem, 15g of achyranthes root, 15g of semiaquilegia root, 15g of cowherb root, 15g of tetragonal diamond, 15g of cibot rhizome, 15g of white diamond, 15g of fiveleaf gynostemma herb and 15g of corydalis tuber are poured into the raw materials, the raw materials are respectively crushed, sieved by a 100-mesh sieve and packaged to obtain the traditional Chinese medicine for treating femoral head necrosis.
Example 3:
the traditional Chinese medicine for treating femoral head necrosis is prepared from the following raw materials in parts by weight: 22g of water hyacinth, 12g of angelica sinensis, 18g of achyranthes bidentata, 12g of semipoetic stem, 18g of caudate dock root, 12g of tetragonal diamond, 18g of rhizoma cibotii, 12g of white diamond, 18g of gynostemma pentaphylla and 12g of corydalis tuber.
The preparation method of the traditional Chinese medicine for treating femoral head necrosis comprises the following steps:
respectively weighing the following raw materials by weight: 22g of water hyacinth, 12g of angelica sinensis, 18g of achyranthes bidentata, 12g of semipoetic stem, 18g of caudate dock root, 12g of tetragonal diamond, 18g of rhizoma cibotii, 12g of white diamond, 18g of gynostemma pentaphyllum and 12g of corydalis tuber are poured into the mixture, and the mixture is respectively crushed, sieved by a 100-mesh sieve and packaged to obtain the traditional Chinese medicine for treating femoral head necrosis.
And (3) clinical observation:
1. case selection: 42 patients in the group, aged 45-68, were all patients with femoral head necrosis.
2. Method of treatment
Taking 1 dose of the traditional Chinese medicine for treating femoral head necrosis prepared in the embodiment 1, the embodiment 2 or the embodiment 3, decocting for 2-3 times per day, 1 dose for 1 day, 1 course for 10 days, and taking for 3-5 courses, wherein spicy food is avoided during the taking period.
3. Clinical symptoms
(1) The medical history: history of trauma; history of large amounts of hormones; chronic alcoholism; rheumatism and rheumatoid diseases; history of ankylosing spondylitis; congenital dislocation of the hip joint, etc. (2) Signs of symptoms: hip and knee pain, limited functional movement of the hip joint, greater trochanter or bone longitudinal axis percussive pain, groin tenderness; the test of the character '4' is positive, the straight leg is raised positive, the gluteus or thigh muscle is flaccid, and the like. (3) X-ray, CT, ECT examination: increased absorption of nuclides, altered bone density, irregular or effaced trabeculae, altered bone cysts, sclerotin sclerosis and cartilage fractures, collapse, narrowing or effacement of joint spaces.
4. Standard of care
The effect is shown: clinical subjective symptoms disappear, joint movement returns to normal, X-ray film: the density of the femoral head is uniform, the arrangement of the trabeculae is neat, and the repair of the sclerotin is neat.
The method has the following advantages: clinical subjective symptoms basically disappear, hip joint movement is limited, and X-ray films: the bone destruction has no obvious repair.
And (4) invalidation: no change is found in the clinical subjective symptom X-ray examination.
5. Clinical results
Of 42 patients, 34 cases (80.95%) were effective, 5 cases (11.9%) were effective, 3 cases (7.15%) were ineffective, and the total effective rate was 92.86%.
6. Typical cases
Case 1: for the rest, male, 56 years old, pain in femoral heads on both sides, limited movement, inability to walk, aggravation after movement, hip joint pain, atrophy of muscles of lower limbs, and bilateral femoral head necrosis diagnosed by CT. The traditional Chinese medicine for treating femoral head necrosis prepared in the embodiment 1 is taken for 1 dose, decocted for 2-3 times per day, 1 dose in 1 day and 10 days for 1 course of treatment. After 3 treatment courses, the patients are cured. The disease does not relapse after 1 year of follow-up visit.
Case 2: wangzhi, female, age 49, pain in both lower limbs, restricted movement, aggravated after movement, and confirmed bilateral femoral head necrosis by CT and X-ray film. The Chinese medicament for treating the femoral head necrosis, which is prepared in the embodiment 2, is taken in 1 dose, decocted 2-3 times per day, 1 dose in 1 day and 10 days for 1 course of treatment. After 2 treatment courses, the patients are cured. The disease does not relapse after 1 year of follow-up visit.
Case 3: anysome, female, age 65, lameness, right hip pain, restricted mobility, CT diagnosis bilateral femoral head necrosis. The Chinese medicament for treating the femoral head necrosis, which is prepared in the embodiment 3, is taken in 1 dose, decocted 2-3 times per day, 1 dose in 1 day and 10 days for 1 course of treatment. After 3 treatment courses, the patients are cured. No recurrence occurred in 8 months of follow-up.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.

Claims (9)

1. The traditional Chinese medicine for treating femoral head necrosis is characterized by being prepared from the following raw materials in parts by weight: 18g-22g of water hyacinth, 12g-18g of angelica sinensis, 12g-18g of achyranthes bidentata, 12g-18g of semipocurrent, 12g-18g of boenninghausenia herb, 12g-18g of rhubard, 12g-18g of cibotium barometz, 12g-18g of rhubard, 12g-18g of gynostemma pentaphylla and 12g-18g of corydalis tuber.
2. The traditional Chinese medicine for treating femoral head necrosis according to claim 1, which is prepared from the following raw materials in parts by weight: 18g of water hyacinth, 18g of angelica sinensis, 12g of achyranthes bidentata, 18g of semipowde, 12g of cauda equisetifolia, 18g of tetragonal diamond, 12g of rhizoma cibotii, 18g of white diamond, 12g of gynostemma pentaphyllum and 18g of corydalis tuber.
3. The traditional Chinese medicine for treating femoral head necrosis according to claim 1, which is prepared from the following raw materials in parts by weight: 20g of water hyacinth, 15g of Chinese angelica stem, 15g of achyranthes root, 15g of semiaquilegia root, 15g of cowherb root, 15g of tetragonal diamond, 15g of cibot rhizome, 15g of white diamond, 15g of fiveleaf gynostemma herb and 15g of corydalis tuber.
4. The traditional Chinese medicine for treating femoral head necrosis according to claim 1, which is prepared from the following raw materials in parts by weight: 22g of water hyacinth, 12g of angelica sinensis, 18g of achyranthes bidentata, 12g of semipoetic stem, 18g of caudate dock root, 12g of tetragonal diamond, 18g of rhizoma cibotii, 12g of white diamond, 18g of gynostemma pentaphylla and 12g of corydalis tuber.
5. The preparation method of the traditional Chinese medicine for treating femoral head necrosis is characterized by comprising the following steps:
respectively weighing the following raw materials by weight: 18g-22g of water hyacinth, 12g-18g of angelica sinensis, 12g-18g of achyranthes bidentata, 12g-18g of semipocurrent, 12g-18g of boehtail, 12g-18g of rhubard, 12g-18g of cibotium barometz, 12g-18g of rhubard, 12g-18g of gynostemma pentaphylla and 12g-18g of corydalis tuber, and the traditional Chinese medicine for treating femoral head necrosis is obtained after the raw materials are respectively crushed, sieved and packaged.
6. The preparation method of the traditional Chinese medicine for treating femoral head necrosis according to claim 5, wherein the weight of the raw materials is as follows: 18g of water hyacinth, 18g of angelica sinensis, 12g of achyranthes bidentata, 18g of semipowde, 12g of cauda equisetifolia, 18g of tetragonal diamond, 12g of rhizoma cibotii, 18g of white diamond, 12g of gynostemma pentaphyllum and 18g of corydalis tuber.
7. The preparation method of the traditional Chinese medicine for treating femoral head necrosis according to claim 5, wherein the weight of the raw materials is as follows: 20g of water hyacinth, 15g of Chinese angelica stem, 15g of achyranthes root, 15g of semiaquilegia root, 15g of cowherb root, 15g of tetragonal diamond, 15g of cibot rhizome, 15g of white diamond, 15g of fiveleaf gynostemma herb and 15g of corydalis tuber.
8. The preparation method of the traditional Chinese medicine for treating femoral head necrosis according to claim 5, wherein the weight of the raw materials is as follows: 22g of water hyacinth, 12g of angelica sinensis, 18g of achyranthes bidentata, 12g of semipoetic stem, 18g of caudate dock root, 12g of tetragonal diamond, 18g of rhizoma cibotii, 12g of white diamond, 18g of gynostemma pentaphylla and 12g of corydalis tuber.
9. The preparation method of the traditional Chinese medicine for treating femoral head necrosis according to any one of claims 5 to 8, wherein the aperture of the sieve is 100 meshes.
CN202011181681.8A 2020-10-29 2020-10-29 Traditional Chinese medicine for treating femoral head necrosis and preparation method thereof Withdrawn CN112138111A (en)

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