CN105169056A - Chinese herb preparation for preventing and treating cerebral cancer and preparation method thereof - Google Patents
Chinese herb preparation for preventing and treating cerebral cancer and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a Chinese herb preparation for preventing and treating a cerebral cancer. The Chinese herb preparation is prepared from, by weight, 10-16 parts of cordyceps sinensis, 8-13 parts of ilex cornuta lindl, 6-9 parts of burmann cinnamon bark, 9-15 parts of ranunculus ternatus, 7-13 parts of stephania tetrandra S. Moore var. glabra Maxim, 6-12 parts of amorphophalms konjac, 10-14 parts of eragrostis pilosa, 12-18 parts of croakers, 9-16 parts of tremella fuciformis, 8-14 parts of aleuritopteris, 9-13 parts of sedum sarmentosum, 6-11 parts of acacia sons, 8-12 parts of morinda officinalis, 10-16 parts of myriaceis nepalensis less., 8-15 parts of kumquat roots and 9-14 parts of himalayan willow herbs. The common Chinese herbs are adopted for being finely prepared into the Chinese herb preparation, medication is strict, the herbs are compatible, and the Chinese herb preparation has the functions of resisting the cancer, achieving detoxification, eliminating phlegm and freeing channels and removing stasis and opening orifices, has a strong killing effect on cerebral cancer cells, improves immunity of a patient with the cancer, and is high in safety and free of side effects.
Description
Technical field
The invention belongs to traditional Chinese medicine field, especially relate to a kind of Chinese medicine composition and preparation method of preventing and treating the brain cancer.
Background technology
Cerebroma comprises various intracranial tumor, and have optimum and pernicious dividing, malignant brain tumor is also known as the brain cancer.Because the profile of cranial cavity is skeleton entirely, if so the raw struma of brain, then the pressure in cranial cavity can be made to increase, thus produce headache, vomiting, sight line is unclear, knots, stupor etc.In malignant brain tumor late period, tumor cell also can be transferred to health other organs.The cerebral tumor is defined as any intracranial tumor, and the position of generation includes the various cell of brain itself (neuron, glial cell, lymphoid tissue and blood vessel), cranial nerve (Schwann cell), meninges, skull, hypophysis and the metastatic brain tumor by other organ metastasis.Cerebroma comprises the primary brain tumor occurred by brain essence and the Secondary cases cerebroma being transferred to intracranial by other positions of health.Primary intracranial tumor incidence rate is without obvious sex difference, and man is slightly more than female.Benign encephaloma poor growth, peplos is more complete, not infiltrate surrounding tissues and well differentiated; Malignant brain tumor growth is very fast, and without peplos, boundary is not obvious, in infiltrative growth, and poorly differentiated.No matter optimum or pernicious, all can extrude, pass normal cerebral tissue, cause intracranial pressure to raise, threaten the life of people.
In recent years, intracranial tumor sickness rate is in rising trend, and according to statistics, intracranial tumor accounts for 5% of general tumour, and other malignant tumor finally has 20-30% proceeds to intracranial, due to the infiltrative growth that it expands, at intracranial once occupy certain space, no matter its character is optimum or pernicious, intracranial pressure all certainly will be made to raise, compressing cerebral tissue, causes nervus centralis to damage, jeopardizes patient vitals.Intracranial tumor can betide any age, is the most common with 20-50 year.Juvenile with posterior cranial fossa and center line tumor more common, be mainly medulloblastoma, craniopharyngioma and ependymoma.Adult is the most common with cerebral hemisphere glioma, if secondly astrocytoma, glioblastoma multiforme, ependymoma etc. are meningioma, pituitary tumor and craniopharyngioma, neurofibroma, cavernous hemangioma, cholesteatoma etc.
The method of the existing Chinese traditional treatment brain cancer is less, publication number CN103272109A(application number 201310241277.9) patent discloses a kind of medicament for the treatment of the brain cancer, it comprises the material of following weight proportioning: Rhizoma Arisaematis 20-50 part, Radix Gei japonici 50-70 part, Rhizoma Paridis 12-15 part, Fructus Forsythiae 20-25 part, Spica Prunellae 20-30 part, Radix Rehmanniae 20-25 part, Radix Cudraniae 20-25 part, Rhizoma Dioscoreae 15-21 part, Os Draconis 20-25 part, Semen Juglandis 20-30 part and Rhizoma Pinelliae 15-20 part.Publication number CN104013833A(application number 201410280147.0) patent discloses a kind of pharmaceutical composition for the treatment of the brain cancer, this pharmaceutical composition is made up of the raw material of following weight parts: Fructus Viticis 12-24 part, Semen Sinapis Albae 12-24 part, Ramulus Uncariae Cum Uncis 12-24 part, Flos Carthami 12-24 part, Rhizoma Chuanxiong 12-24 part, Radix Salviae Miltiorrhizae 12-24 part, Rhizoma Gastrodiae 12-24 part, Radix Polygoni Multiflori 12-24 part, Rhizoma Cimicifugae 12-24 part, Sanguis Draxonis 9-21 part, Scolopendra 9-21 part, Semen Persicae 9-21 part, Squama Manis 9-21 part, Radix Notoginseng 9-21 part, Borneolum Syntheticum 9-21 part, Indigo Naturalis 9-21 part, Calomelas 9-21 part.Publication number CN104840748A(application number 201510254817.6) patent discloses and a kind of there is Chinese medicine composition of anti-brain cancer activity and its preparation method and application, it is made up of the crude drug of following parts by weight: Rhizoma Typhonii (processed) 10-30 part, Pseudobulbus Cremastrae Seu Pleiones 15-45 part, Scolopendra 3-9 part, Rhizoma Arisaematis (processed) 10-30 part, Herba Lycopi 10-30 part, Rhizoma Alismatis 10-30 part.
At present, Therapeutic cancer many employings doctor trained in Western medicine, common is operation, chemotherapy, radiotherapy, and the wound of operative treatment to human body is more, and operation can only the state of an illness of controls local, helpless for the brain cancer occurring to shift; And Radiotherapy chemotherapy produces larger toxic and side effects, while killing cancerous cell, also murder very fiery normal cell, caused the adverse consequencess such as body immune hypofunction.And at present the traditional Chinese medical science is to the treatment of the brain cancer also unusual imperfection, medicine is few, and curative effect is indefinite.
Summary of the invention
For the deficiencies in the prior art, an object of the present invention is to provide a kind of Chinese medicine composition preventing and treating the brain cancer, adopt Common Chinese Herbs to refine to form, medication is rigorous, all medicine compatibilities, has anticancer removing toxic substances, effect that eleminating phlegm and freeing channels, eliminating stagnation are had one's ideas straightened out, to brain cancer cell, there is stronger killing action, improve tumor patient immunity, and safety is high, has no side effect.Another object of the present invention is to provide above-mentioned a kind of preparation method of preventing and treating the Chinese medicine composition of the brain cancer.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
Prevent and treat a Chinese medicine composition for the brain cancer, take off the primary raw material stating weight proportion and be prepared from: Cordyceps 10-16 part; Fructus Mahoniae 8-13 part; Cortex Cinnamomi Burmannii 6-9 part; Radix Ranunculi Ternati 9-15 part; Radix Cissi Kerrii 7-13 part; Rhizoma amorphophalli 6-12 part; Herba Eragrostidis pilosae 10-14 part; Carnis Pseudosciaenae 12-18 part; Tremella 9-16 part; Aleuritopteris farinsa (Forsk.) Fee 8-14 part; Herba Sedi 9-13 part; Semen Gleditsiae 6-11 part; Radix Morindae Officinalis 8-12 part; Oil head grass 10-16 part; Radix Fortunellae Margaritae 8-15 part; Herba Epilobii Himalayensis 9-14 part.
Prevent and treat a Chinese medicine composition for the brain cancer, preferred scheme is, takes off the primary raw material stating weight proportion and is prepared from: Cordyceps 12-14 part; Fructus Mahoniae 10-12 part; Cortex Cinnamomi Burmannii 7-8 part; Radix Ranunculi Ternati 11-13 part; Radix Cissi Kerrii 9-11 part; Rhizoma amorphophalli 8-10 part; Herba Eragrostidis pilosae 11-13 part; Carnis Pseudosciaenae 14-16 part; Tremella 12-14 part; Aleuritopteris farinsa (Forsk.) Fee 10-12 part; Herba Sedi 10-12 part; Semen Gleditsiae 8-10 part; Radix Morindae Officinalis 9-11 part; Oil head grass 12-14 part; Radix Fortunellae Margaritae 11-13 part; Herba Epilobii Himalayensis 11-13 part.
Prevent and treat a Chinese medicine composition for the brain cancer, the scheme be more preferably is, takes off the primary raw material stating weight proportion and is prepared from: Cordyceps 13 parts; Fructus Mahoniae 11 parts; Cortex Cinnamomi Burmannii 7.5 parts; Radix Ranunculi Ternati 12 parts; Radix Cissi Kerrii 10 parts; Rhizoma amorphophalli 9 parts; Herba Eragrostidis pilosae 12 parts; Carnis Pseudosciaenae 15 parts; 13 parts, Tremella; Aleuritopteris farinsa (Forsk.) Fee 11 parts; Herba Sedi 11 parts; Semen Gleditsiae 9 parts; Radix Morindae Officinalis 10 parts; Oil head grass 13 parts; Radix Fortunellae Margaritae 12 parts; Herba Epilobii Himalayensis 12 parts.
Present invention also offers the preparation method above-mentioned a kind of Chinese medicine composition preventing and treating the brain cancer being made pharmaceutically acceptable decoction, granule, concentrated pill, Tablet and Capsula.
Described a kind of preparation method of preventing and treating the Chinese medicine composition decoction of the brain cancer, step is as follows:
(1) pot is burnt heat, add edible oil, after oily heat, add Cordyceps, slow fire is fried to surperficial micro-yellow, takes out, cools, be placed in mortar porphyrize, crosses 140-180 mesh sieve (preferred cross 150-170 mesh sieve, be more preferably 160 mesh sieves);
(2) Carnis Pseudosciaenae is slaughtered, carefully scrape one time with hilt fish skin, stick with paste on fish skin with Semen Glycines powder, rub 3-5 minute, clean, stripping and slicing, be placed in pot, add Rhizoma Zingiberis Recens, Herba Alii fistulosi, cooking wine, add decocting in water 10-20 minute, add Radix Cissi Kerrii, Rhizoma amorphophalli, Tremella, Semen Gleditsiae and Radix Morindae Officinalis, continue to boil 30-40 minute, filter, obtain filtrate 1, continue to add decocting in water 20-30 minute, filter, obtain filtrate 2;
(3) filtrate 1 and filtrate 2 are mixed, add step (1) gained medicated powder, be concentrated into 1/2 of original volume;
(4) Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis are smashed, be placed in container, add white vinegar, moistening 8-10 hour;
(5) Fructus Mahoniae, Cortex Cinnamomi Burmannii, Herba Eragrostidis pilosae, Aleuritopteris farinsa (Forsk.) Fee and Herba Sedi are placed in marmite, soak 20-30 minute, add step (4) gains, decoct twice, each decoction 30-50 minute (preferably each decoction 35-45 minute, is more preferably each decoction 40 minutes), merging filtrate;
(6) by step (3) gained concentrated solution and the mixing of step (5) gained filtrate, add correctives, hold over night, filter, sterile packaged.
According to preparation method recited above, the consumption of the preferred white vinegar of step (4) is the 30%-35% of Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis gross mass, the consumption being more preferably white vinegar be Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis gross mass 33%.
Instructions of taking: each 100-150ml, every day 2 times, 12 days courses for the treatment of.
Described a kind of preparation method of preventing and treating the Chinese medicinal composition granules of the brain cancer, step is as follows:
(1) pot is burnt heat, add edible oil, after oily heat, add Cordyceps, slow fire is fried to surperficial micro-yellow, takes out, cools, be placed in mortar porphyrize, crosses 140-180 mesh sieve (preferred cross 150-170 mesh sieve, be more preferably 160 mesh sieves);
(2) Carnis Pseudosciaenae is slaughtered, scrape one time with hilt fish skin, stick with paste on fish skin with Semen Glycines powder, rub 3-5 minute, clean, be placed in pot, add Rhizoma Zingiberis Recens, Herba Alii fistulosi, cooking wine, add decocting in water 10-20 minute, add Radix Cissi Kerrii, Rhizoma amorphophalli, Tremella, Semen Gleditsiae and Radix Morindae Officinalis, continue to boil 30-40 minute, filter, obtain filtrate 1, continue to add decocting in water 20-30 minute, filter, obtain filtrate 2;
(3) filtrate 1 and filtrate 2 are mixed, add step (1) gained medicated powder, be concentrated into 1/2 of original volume;
(4) Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis are smashed, be placed in container, (consumption of preferred white vinegar is the 30%-35% of Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis gross mass to add white vinegar, the consumption being more preferably white vinegar be Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis gross mass 33%), moistening 8-10 hour;
(5) Fructus Mahoniae, Cortex Cinnamomi Burmannii, Herba Eragrostidis pilosae, Aleuritopteris farinsa (Forsk.) Fee and Herba Sedi are placed in marmite, soak 20-30 minute, add step (4) gains, decoct twice, each decoction 30-50 minute (preferably each decoction 35-45 minute, is more preferably each decoction 40 minutes), merging filtrate;
(6) by step (3) gained concentrated solution and the mixing of step (5) gained filtrate, hold over night, filters, be concentrated into relative density 1.10-1.20(25 DEG C) thick paste, make uniform fine particle, be aided with pharmaceutically acceptable carrier package, the quality of every parcel is 6g.
According to preparation method recited above, step (6) is preferably concentrated into the thick paste of relative density 1.13-1.17, is more preferably the thick paste being concentrated into relative density 1.15.
Instructions of taking: each 1 bag, takes after melting, every day 2 times, 12 days courses for the treatment of by warm water.
Described a kind of preparation method of preventing and treating the Chinese medicine composition concentrated pill of the brain cancer, step is as follows:
(1) pot is burnt heat, add edible oil, after oily heat, add Cordyceps, slow fire is fried to surperficial micro-yellow, takes out, cools, be placed in mortar porphyrize, crosses 140-180 mesh sieve (preferred cross 150-170 mesh sieve, be more preferably 160 mesh sieves);
(2) Carnis Pseudosciaenae is slaughtered, scrape one time with hilt fish skin, stick with paste on fish skin with Semen Glycines powder, rub 3-5 minute, clean, be placed in pot, add Rhizoma Zingiberis Recens, Herba Alii fistulosi, cooking wine, add decocting in water 10-20 minute, add Radix Cissi Kerrii, Rhizoma amorphophalli, Tremella, Semen Gleditsiae and Radix Morindae Officinalis, continue to boil 30-40 minute, filter, obtain filtrate 1, continue to add decocting in water 20-30 minute, filter, obtain filtrate 2;
(3) filtrate 1 and filtrate 2 are mixed, add step (1) gained medicated powder, be concentrated into 1/2 of original volume;
(4) Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis are smashed, be placed in container, (consumption of preferred white vinegar is the 30%-35% of Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis gross mass to add white vinegar, the consumption being more preferably white vinegar be Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis gross mass 33%), moistening 8-10 hour;
(5) Fructus Mahoniae, Cortex Cinnamomi Burmannii, Herba Eragrostidis pilosae, Aleuritopteris farinsa (Forsk.) Fee and Herba Sedi are placed in marmite, soak 20-30 minute, add step (4) gains, decoct twice, each decoction 30-50 minute (preferably each decoction 35-45 minute, is more preferably each decoction 40 minutes), merging filtrate;
(6) by step (3) gained concentrated solution and the mixing of step (5) gained filtrate, hold over night, filter, be concentrated into relative density 1.10-1.20(25 DEG C) thick paste (be preferably concentrated into the thick paste of relative density 1.13-1.17, be more preferably the thick paste being concentrated into relative density 1.15), make concentrated pill (preferred diameter is 3-5mm, and being more preferably diameter is 4mm), sterile packaged.
Using method: each 6-10 ball, with warm water delivery service, every day 2 times, 12 days courses for the treatment of.
Described a kind of preparation method of preventing and treating the Chinese medicine composition tablet of the brain cancer, step is as follows:
(1) pot is burnt heat, add edible oil, after oily heat, add Cordyceps, slow fire is fried to surperficial micro-yellow, takes out, cools, be placed in mortar porphyrize, crosses 140-180 mesh sieve (preferred cross 150-170 mesh sieve, be more preferably 160 mesh sieves);
(2) Carnis Pseudosciaenae is slaughtered, scrape one time with hilt fish skin, stick with paste on fish skin with Semen Glycines powder, rub 3-5 minute, clean, be placed in pot, add Rhizoma Zingiberis Recens, Herba Alii fistulosi, cooking wine, add decocting in water 10-20 minute, add Radix Cissi Kerrii, Rhizoma amorphophalli, Tremella, Semen Gleditsiae and Radix Morindae Officinalis, continue to boil 30-40 minute, filter, obtain filtrate 1, continue to add decocting in water 20-30 minute, filter, obtain filtrate 2;
(3) filtrate 1 and filtrate 2 are mixed, add step (1) gained medicated powder, be concentrated into 1/2 of original volume;
(4) Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis are smashed, be placed in container, (consumption of preferred white vinegar is the 30%-35% of Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis gross mass to add white vinegar, the consumption being more preferably white vinegar be Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis gross mass 33%), moistening 8-10 hour;
(5) Fructus Mahoniae, Cortex Cinnamomi Burmannii, Herba Eragrostidis pilosae, Aleuritopteris farinsa (Forsk.) Fee and Herba Sedi are placed in marmite, soak 20-30 minute, add step (4) gains, decoct twice, each decoction 30-50 minute (preferably each decoction 35-45 minute, is more preferably each decoction 40 minutes), merging filtrate;
(6) by step (3) gained concentrated solution and the mixing of step (5) gained filtrate, hold over night, filter, be concentrated into relative density 1.10-1.20(25 DEG C) thick paste (be preferably concentrated into the thick paste of relative density 1.13-1.17, be more preferably the thick paste being concentrated into relative density 1.15), make tablet.
Instructions of taking: each 2-3 sheet, every day 2 times, 12 days courses for the treatment of.
Described a kind of preparation method of preventing and treating the Chinese medicinal composition capsules of the brain cancer, step is as follows:
(1) pot is burnt heat, add edible oil, after oily heat, add Cordyceps, slow fire is fried to surperficial micro-yellow, takes out, cools, be placed in mortar porphyrize, crosses 140-180 mesh sieve (preferred cross 150-170 mesh sieve, be more preferably 160 mesh sieves);
(2) Carnis Pseudosciaenae is slaughtered, scrape one time with hilt fish skin, stick with paste on fish skin with Semen Glycines powder, rub 3-5 minute, clean, be placed in pot, add Rhizoma Zingiberis Recens, Herba Alii fistulosi, cooking wine, add decocting in water 10-20 minute, add Radix Cissi Kerrii, Rhizoma amorphophalli, Tremella, Semen Gleditsiae and Radix Morindae Officinalis, continue to boil 30-40 minute, filter, obtain filtrate 1, continue to add decocting in water 20-30 minute, filter, obtain filtrate 2;
(3) filtrate 1 and filtrate 2 are mixed, add step (1) gained medicated powder, be concentrated into 1/2 of original volume;
(4) Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis are smashed, be placed in container, (consumption of preferred white vinegar is the 30%-35% of Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis gross mass to add white vinegar, the consumption being more preferably white vinegar be Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis gross mass 33%), moistening 8-10 hour;
(5) Fructus Mahoniae, Cortex Cinnamomi Burmannii, Herba Eragrostidis pilosae, Aleuritopteris farinsa (Forsk.) Fee and Herba Sedi are placed in marmite, soak 20-30 minute, add step (4) gains, decoct twice, each decoction 30-50 minute (preferably each decoction 35-45 minute, is more preferably each decoction 40 minutes), merging filtrate;
(6) by step (3) gained concentrated solution and the mixing of step (5) gained filtrate, hold over night, filter, be concentrated into relative density 1.20-1.30(25 DEG C) thick paste (be preferably concentrated into the thick paste of relative density 1.23-1.27, be more preferably the thick paste being concentrated into relative density 1.25), dry, pulverize, cross 180-200 mesh sieve, make capsule (preferred 0.4-0.6g/ grain, is more preferably 0.5g/ grain).
Instructions of taking: each 2-3 grain, every day 2 times, 12 days courses for the treatment of.
The pharmacological effect of each crude drug is respectively:
Cordyceps: sweet in the mouth, property is put down.Return lung, kidney channel.For section ergot fungus cordyceps sinensis bacterium colonizes in Stroma on Bian Fu pretty young woman section insect larvae and larva cadaveric complex.There is invigorating the lung and the kidney, hemostasis, the effect of reducing phlegm.For chronic cough dyspnea due to deficiency, chronic cough is spat blood, and sexual impotence is passed out semen, soreness of waist and knee joint.
Fructus Mahoniae: bitter in the mouth, cool in nature.Return spleen, kidney, urinary bladder channel.For the fruit of Berberidaceae plant broad-leaved ten large merit, mahonia fortuneiFedde etc.Containing a large amount of isosinomenines and berbamine.There is clearind deficient heat, the kidney invigorating, effect of dampness.For osteopyrexia and fever, soreness of the waist and knees, dizziness and tinnitus, damp-heat diarrhea, leukorrhagia, stranguria with turbid discharge.
Cortex Cinnamomi Burmannii: acrid in the mouth, micro-sweet, warm in nature.Return spleen channel.For the cloudy fragrant bark of canella.Containing volatile oil, the main component in oil is cinnamic aldehyde, in addition containing eugenol, and the compositions such as safrole.There is warming middle-JIAO to relieve pain, expelling wind and cold, removing toxic substances and promoting subsidence of swelling, effect of hemostasis.For curing mainly cold stomachache, stomachache is had loose bowels, inappetence, anemofrigid-damp arthralgia, lumbago and skelalgia, traumatic injury, wound hemorrhage, furuncle toxic swelling.
Radix Ranunculi Ternati: sweet in the mouth, pungent, warm in nature.Return liver, lung meridian.For the dried root of ranunculaceae plant Seynuns Kugelann.There is eliminating stagnation, effect of detumescence.Do not burst for scrofula, tuberculous lymphadenitis.
Radix Cissi Kerrii: bitter in the mouth, micro-pungent, cool in nature.GUIXIN, kidney channel.For the tuber of vitaceae Cissus repens.Containing phenols, aminoacid, Saponin, organic acid.There is promoting blood circulation to remove obstruction in the collateral, dissipating phlegm and resolving masses, effect of removing toxicity for eliminating carbuncles.For traumatic injury, rheumatic arthralgia, scrofula sucutaneous nodule, carbuncle sore tumefacting virus, venom.
Rhizoma amorphophalli: acrid in the mouth, hardship, cold in nature.For aroid mill taro, the tuber dredging hair mill taro, wild mill taro, Rhizoma Amorphophalli.Containing glucomannan, mannan, glycerol, citric acid, ferulic acid, cinnamic acid, methyl palmitic acid, heneicosene, cupreol.There is transforming phlegm and dispersing accumulations, detoxicating and resolving stagnation of pathogens, effect of clots absorbing pain relieving.For phlegmatic cough, stagnant, malaria, scrofula, lump in the abdomen, traumatic injury, carbuncle, furuncle, erysipelas, burn and scald, venom.
Herba Eragrostidis pilosae: sweet in the mouth, light, cool in nature.For the herb of grass Herba Eragrostidis pilosae.There is inducing diuresis for treating stranguria syndrome, effect of heat clearing and blood circulation promoting.For pyretic stranguria, stranguria caused by urinary stone, conjunctival congestion is itched bitterly, traumatic injury.
Carnis Pseudosciaenae: sweet in the mouth, property is put down.Return spleen, stomach, liver, kidney channel.For the meat of Sciaenidae animal Carnis Pseudosciaenae and Carnis Pseudosciaenae.Containing protein, fat, ash, calcium, phosphorus, ferrum, thiamine, riboflavin, nicotinic acid, iodine etc.There is replenishing QI to invigorate the spleen, the kidney invigorating, improving eyesight, effect of dysentery relieving.For after being ill, puerperal asthenia, hypogalactia, lumbago due to renal deficiency, edema, blurring of vision, headache, stomachache, dysentery.
Tremella: sweet in the mouth, light, property is put down.Return lung, stomach, kidney channel.For the sporophore of Tremellaceae Tremella.Containing Tremella fructification polysaccharide, tremella polysaccharide spore, polysaccharide TP-1, glycoprotein TP, cell wall polysaccharides, glucuronoxylose mannan, neutral polysaccharide.There is nourishing promote the production of body fluid, effect of lung moistening nourishing the stomach.For cough due to consumptive disease, sputum mixed with blood, Tianjin is few thirsty, and body is empty after being ill, shortness of breath and fatigue.
Aleuritopteris farinsa (Forsk.) Fee: lightly seasoned, micro-puckery, warm in nature.Return lung, spleen, Liver Channel.For the herb of Sinopteridaceae plant Aleuritopteris farinsa (Forsk.) Fee.There is expelling phlegm for arresting cough, invigorating spleen to remove dampness, effect of promoting blood circulation and hemostasis.For cough, have loose bowels, dysentery, dyspepsia, menoxenia, spits blood, has blood in stool, leucorrhea, stranguria, traumatic injury, scrofula.
Herba Sedi: sweet in the mouth, light, cool in nature.Return liver, gallbladder, small intestine meridian.For the fresh or dry herb of crassulaceae plants Herba Sedi.There is eliminating damp-heat, effect of removing toxic substances.For jaundice due to damp-heat, dysuria, carbuncle skin infection, acute hepatitis, chronic hepatitis.
Semen Gleditsiae: acrid in the mouth, warm in nature.Return lung, large intestine channel.For the seed of leguminous plant Fructus Gleditsia.Gummy, galactose, mannose.Several days loosening bowel to relieve constipation, wind and heat eliminating, effect of dissipating phlegm and resolving masses.For constipation due to dry stool, discharging fresh blood stool, dysentery, tenesmus, phlegm dyspnea generalized edema with distention of the chest and abdomen, hernia pain, scrofula, toxic swelling, skin ulcer tinea.
Radix Morindae Officinalis: sweet in the mouth, pungent, warm in nature.Return kidney, Liver Channel.For the root of Maguireothamnus speciosus Radix Morindae Officinalis.There is kidney-replenishing, bone and muscle strengthening, effect of wind-damp dispelling.For impotence and seminal emission, cold womb is infertile, menoxenia, and few abdomen cold type of pain, rheumatic arthralgia, muscles and bones flaccidity is soft.
Oil head grass: taste is micro-pungent, property is put down.For feverfew circle tongue glues root or the herb of hat grass.There is heat-clearing and toxic substances removing, elegant rash, effect of pain relieving.For dysentery, enteritis, otitis media, measles is sent out not smooth thoroughly, toothache, arthralgia.
Radix Fortunellae Margaritae: sour in the mouth, hardship, warm in nature.Return spleen, stomach, Liver Channel.For the root of rutaceae Fructus Fortunellae Margaritae, golden bullet, Fortunella crassifolia Swingle.Containing volatile oil.There are promoting the circulation of QI to relieve pain, effect of dissipating phlegm and resolving masses.For epigastric distending pain, hernia, puerperal abdonimal pain, uterine prolapse, scrofula from the beginning of.
Herba Epilobii Himalayensis: acrid in the mouth, light, property is put down.Return lung, Liver Channel.For the herb of onagraceae plant Yunnan-Tibet LIUYECAI.There is wind and heat dispersing, dampness removing antidiarrheal, the effect of synthetism of invigorating blood circulation.For headache due to pathogenic wind-heat, laryngopharynx swelling and pain, hoarseness, diarrhoea, amenorrhea, sore and toxic, injury and bone fracture.
Technical advantage of the present invention is mainly reflected in:
1, a kind of Chinese medicine composition employing Common Chinese Herbs preventing and treating the brain cancer of the present invention is refined and is formed, proportioning is scientific and reasonable, medication is rigorous, all medicine compatibilities, there is anticancer removing toxic substances, effect that eleminating phlegm and freeing channels, eliminating stagnation are had one's ideas straightened out, to brain cancer cell, there is stronger killing action, and the generation of tumor necrosis factor can be promoted, improve tumor patient immunity.
2, Chinese medicine composition of the present invention adopts the theory of determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs to carry out Chinese prescription screening, and experiment shows that Chinese medicine composition of the present invention has and well suppresses brain cancer cell growth and can promote the apoptotic effect of brain tumor.
3, Chinese medicine composition of the present invention adopts Common Chinese Herbs, and medical material is easy to get, and cost is low, has no side effect, and operation is simple, and safety is high, and steady quality is workable, is applicable to industrialized great production.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
embodiment 1prevent and treat a Chinese medicine composition for the brain cancer, take off and state primary raw material and be prepared from (getting 80g for every part): Cordyceps 10 parts; Fructus Mahoniae 8 parts; Cortex Cinnamomi Burmannii 6 parts; Radix Ranunculi Ternati 9 parts; Radix Cissi Kerrii 7 parts; Rhizoma amorphophalli 6 parts; Herba Eragrostidis pilosae 10 parts; Carnis Pseudosciaenae 12 parts; 9 parts, Tremella; Aleuritopteris farinsa (Forsk.) Fee 8 parts; Herba Sedi 9 parts; Semen Gleditsiae 6 parts; Radix Morindae Officinalis 8 parts; Oil head grass 10 parts; Radix Fortunellae Margaritae 8 parts; Herba Epilobii Himalayensis 9 parts.
Above-mentioned a kind of preparation method of preventing and treating the Chinese medicine composition decoction of the brain cancer, step is as follows:
(1) pot is burnt heat, add edible oil, after oily heat, add Cordyceps, slow fire is fried to surperficial micro-yellow, takes out, cools, be placed in mortar porphyrize, crosses 160 mesh sieves;
(2) Carnis Pseudosciaenae is slaughtered, carefully scrape one time with hilt fish skin, stick with paste on fish skin with Semen Glycines powder, rub 4 minutes, clean, stripping and slicing, be placed in pot, add Rhizoma Zingiberis Recens, Herba Alii fistulosi, cooking wine, add decocting in water 15 minutes, add Radix Cissi Kerrii, Rhizoma amorphophalli, Tremella, Semen Gleditsiae and Radix Morindae Officinalis, continue to boil 35 minutes, filter, obtain filtrate 1, continue to add decocting in water 25 minutes, filter, obtain filtrate 2;
(3) filtrate 1 and filtrate 2 are mixed, add step (1) gained medicated powder, be concentrated into 1/2 of original volume;
(4) Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis are smashed, are placed in container, add white vinegar (consumption be Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis gross mass 33%), moistening 9 hours;
(5) Fructus Mahoniae, Cortex Cinnamomi Burmannii, Herba Eragrostidis pilosae, Aleuritopteris farinsa (Forsk.) Fee and Herba Sedi are placed in marmite, soak 25 minutes, add step (4) gains, decoct twice, each decoction 40 minutes, merging filtrate;
(6) by step (3) gained concentrated solution and the mixing of step (5) gained filtrate, add correctives, hold over night, filter, sterile packaged.
Instructions of taking: each 100-150ml, every day 2 times, 12 days courses for the treatment of.
embodiment 2prevent and treat a Chinese medicine composition for the brain cancer, take off and state primary raw material and be prepared from (getting 30g for every part): Cordyceps 16 parts; Fructus Mahoniae 13 parts; Cortex Cinnamomi Burmannii 9 parts; Radix Ranunculi Ternati 15 parts; Radix Cissi Kerrii 13 parts; Rhizoma amorphophalli 12 parts; Herba Eragrostidis pilosae 14 parts; Carnis Pseudosciaenae 18 parts; 16 parts, Tremella; Aleuritopteris farinsa (Forsk.) Fee 14 parts; Herba Sedi 13 parts; Semen Gleditsiae 11 parts; Radix Morindae Officinalis 12 parts; Oil head grass 16 parts; Radix Fortunellae Margaritae 15 parts; Herba Epilobii Himalayensis 14 parts.
Above-mentioned a kind of preparation method of preventing and treating the Chinese medicinal composition granules of the brain cancer, step is as follows:
(1) pot is burnt heat, add edible oil, after oily heat, add Cordyceps, slow fire is fried to surperficial micro-yellow, takes out, cools, be placed in mortar porphyrize, crosses 160 mesh sieves;
(2) Carnis Pseudosciaenae is slaughtered, scrape one time with hilt fish skin, stick with paste on fish skin with Semen Glycines powder, rub 4 minutes, clean, be placed in pot, add Rhizoma Zingiberis Recens, Herba Alii fistulosi, cooking wine, add decocting in water 15 minutes, add Radix Cissi Kerrii, Rhizoma amorphophalli, Tremella, Semen Gleditsiae and Radix Morindae Officinalis, continue to boil 35 minutes, filter, obtain filtrate 1, continue to add decocting in water 25 minutes, filter, obtain filtrate 2;
(3) filtrate 1 and filtrate 2 are mixed, add step (1) gained medicated powder, be concentrated into 1/2 of original volume;
(4) Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis are smashed, are placed in container, add white vinegar (consumption be Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis gross mass 33%), moistening 9 hours;
(5) Fructus Mahoniae, Cortex Cinnamomi Burmannii, Herba Eragrostidis pilosae, Aleuritopteris farinsa (Forsk.) Fee and Herba Sedi are placed in marmite, soak 25 minutes, add step (4) gains, decoct twice, each decoction 40 minutes, merging filtrate;
(6) by step (3) gained concentrated solution and the mixing of step (5) gained filtrate, hold over night, filters, be concentrated into relative density 1.15(25 DEG C) thick paste, make uniform fine particle, be aided with pharmaceutically acceptable carrier package, the quality of every parcel is 6g.
Instructions of taking: each 1 bag, takes after melting, every day 2 times, 12 days courses for the treatment of by warm water.
model case oneto XX, man, 72 years old, people from Jining City in Shandong Province.Headache, tic, cardio palmus is there is without obvious inducement before being first born in the more than ten years, so remove examination in hospital immediately, CT examination is shown: the focus shade of left side brain visible about 1.8*3.2*2.3 size, is diagnosed as the brain cancer, row operative treatment after checking the consultation of doctors further.After 1 year, occur recurrence sign, keep vomiting, dizziness headache is serious, and health is weak, and appetite is poor, constantly becomes thin.
After taking the present invention a kind of 2 courses for the treatment of of Chinese medicine composition (embodiment 2) of preventing and treating the brain cancer, headache, vomiting, tic symptom alleviate, and the mental status takes a turn for the better.After continuing to take 2 courses for the treatment of, check CT shows and obviously reduces before brain lesion comparatively, and focus is other calcification point, does not find transfer or infiltrate foci.Follow up a case by regular visits to and do not occur recurrence and transfer sign so far, recover better.
embodiment 3prevent and treat a Chinese medicine composition for the brain cancer, take off and state primary raw material and be prepared from (getting 60g for every part): Cordyceps 12 parts; Fructus Mahoniae 10 parts; Cortex Cinnamomi Burmannii 7 parts; Radix Ranunculi Ternati 11 parts; Radix Cissi Kerrii 9 parts; Rhizoma amorphophalli 8 parts; Herba Eragrostidis pilosae 11 parts; Carnis Pseudosciaenae 14 parts; 12 parts, Tremella; Aleuritopteris farinsa (Forsk.) Fee 10 parts; Herba Sedi 10 parts; Semen Gleditsiae 8 parts; Radix Morindae Officinalis 9 parts; Oil head grass 12 parts; Radix Fortunellae Margaritae 11 parts; Herba Epilobii Himalayensis 11 parts.
Above-mentioned a kind of preparation method of preventing and treating the Chinese medicine composition concentrated pill of the brain cancer, step is as follows:
(1) pot is burnt heat, add edible oil, after oily heat, add Cordyceps, slow fire is fried to surperficial micro-yellow, takes out, cools, be placed in mortar porphyrize, crosses 160 mesh sieves;
(2) Carnis Pseudosciaenae is slaughtered, scrape one time with hilt fish skin, stick with paste on fish skin with Semen Glycines powder, rub 4 minutes, clean, be placed in pot, add Rhizoma Zingiberis Recens, Herba Alii fistulosi, cooking wine, add decocting in water 15 minutes, add Radix Cissi Kerrii, Rhizoma amorphophalli, Tremella, Semen Gleditsiae and Radix Morindae Officinalis, continue to boil 35 minutes, filter, obtain filtrate 1, continue to add decocting in water 25 minutes, filter, obtain filtrate 2;
(3) filtrate 1 and filtrate 2 are mixed, add step (1) gained medicated powder, be concentrated into 1/2 of original volume;
(4) Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis are smashed, are placed in container, add white vinegar (consumption be Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis gross mass 33%), moistening 9 hours;
(5) Fructus Mahoniae, Cortex Cinnamomi Burmannii, Herba Eragrostidis pilosae, Aleuritopteris farinsa (Forsk.) Fee and Herba Sedi are placed in marmite, soak 25 minutes, add step (4) gains, decoct twice, each decoction 40 minutes, merging filtrate;
(6) by step (3) gained concentrated solution and step (5) gained filtrate mixing, hold over night, filter, be concentrated into relative density 1.15(25 DEG C) thick paste, make the concentrated pill that diameter is 4mm, sterile packaged.
Using method: each 8 balls, with warm water delivery service, every day 2 times, 12 days courses for the treatment of.
embodiment 4prevent and treat a Chinese medicine composition for the brain cancer, take off and state primary raw material and be prepared from (getting 30g for every part): Cordyceps 14 parts; Fructus Mahoniae 12 parts; Cortex Cinnamomi Burmannii 8 parts; Radix Ranunculi Ternati 13 parts; Radix Cissi Kerrii 11 parts; Rhizoma amorphophalli 10 parts; Herba Eragrostidis pilosae 13 parts; Carnis Pseudosciaenae 16 parts; 14 parts, Tremella; Aleuritopteris farinsa (Forsk.) Fee 12 parts; Herba Sedi 12 parts; Semen Gleditsiae 10 parts; Radix Morindae Officinalis 11 parts; Oil head grass 14 parts; Radix Fortunellae Margaritae 13 parts; Herba Epilobii Himalayensis 13 parts.
Above-mentioned a kind of preparation method of preventing and treating the Chinese medicine composition tablet of the brain cancer, step is as follows:
(1) pot is burnt heat, add edible oil, after oily heat, add Cordyceps, slow fire is fried to surperficial micro-yellow, takes out, cools, be placed in mortar porphyrize, crosses 160 mesh sieves;
(2) Carnis Pseudosciaenae is slaughtered, scrape one time with hilt fish skin, stick with paste on fish skin with Semen Glycines powder, rub 4 minutes, clean, be placed in pot, add Rhizoma Zingiberis Recens, Herba Alii fistulosi, cooking wine, add decocting in water 15 minutes, add Radix Cissi Kerrii, Rhizoma amorphophalli, Tremella, Semen Gleditsiae and Radix Morindae Officinalis, continue to boil 35 minutes, filter, obtain filtrate 1, continue to add decocting in water 25 minutes, filter, obtain filtrate 2;
(3) filtrate 1 and filtrate 2 are mixed, add step (1) gained medicated powder, be concentrated into 1/2 of original volume;
(4) Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis are smashed, are placed in container, add white vinegar (consumption be Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis gross mass 33%), moistening 9 hours;
(5) Fructus Mahoniae, Cortex Cinnamomi Burmannii, Herba Eragrostidis pilosae, Aleuritopteris farinsa (Forsk.) Fee and Herba Sedi are placed in marmite, soak 25 minutes, add step (4) gains, decoct twice, each decoct 40 minutes=, merging filtrate;
(6) by step (3) gained concentrated solution and the mixing of step (5) gained filtrate, hold over night, filters, is concentrated into the thick paste of relative density 1.15, makes tablet.
Using method: each 2-3 sheet, every day 2 times, 12 days courses for the treatment of.
model case twoxX recklessly, female, 59 years old, people from Tai'an, Shandong Province.Before about 6 or seven years, the diseases such as dizziness headache appears in Mrs Hu, and health is weak, tinnitus, do not take notice of very much at that time yet, think it is caused by work fatigue, after this usually occur dizziness headache, nausea and vomiting, until once fall in a swoon suddenly, this just removes examination in hospital, at that time after doctor checks, say it is hypoglycemia, after giving corresponding treatment, symptom was eased.But how long do not maintain, occur above-mentioned symptom again after several days, go regular large hospital by after detailed inspection, be diagnosed as the brain cancer, the chemotherapy of underwent operative and 4 courses for the treatment of, effect is undesirable.
After taking the present invention a kind of 2 courses for the treatment of of Chinese medicine composition (embodiment 4) of preventing and treating the brain cancer, look takes a turn for the better, and dizziness and blurred vision, the symptom such as diplopia, tinnitus obviously alleviates, and diet is better.After continuing to take 2 courses for the treatment of, check brain CT shows focus and substantially disappears, and dizziness headache phenomenon seldom occurs.Follow up a case by regular visits in the time so far more than 3 years and do not occur recurrence, also do not have transfer sign.
embodiment 5prevent and treat a Chinese medicine composition for the brain cancer, take off and state primary raw material and be prepared from (getting 40g for every part): Cordyceps 13 parts; Fructus Mahoniae 11 parts; Cortex Cinnamomi Burmannii 7.5 parts; Radix Ranunculi Ternati 12 parts; Radix Cissi Kerrii 10 parts; Rhizoma amorphophalli 9 parts; Herba Eragrostidis pilosae 12 parts; Carnis Pseudosciaenae 15 parts; 13 parts, Tremella; Aleuritopteris farinsa (Forsk.) Fee 11 parts; Herba Sedi 11 parts; Semen Gleditsiae 9 parts; Radix Morindae Officinalis 10 parts; Oil head grass 13 parts; Radix Fortunellae Margaritae 12 parts; Herba Epilobii Himalayensis 12 parts.
Above-mentioned a kind of preparation method of preventing and treating the Chinese medicinal composition capsules of the brain cancer, step is as follows:
(1) pot is burnt heat, add edible oil, after oily heat, add Cordyceps, slow fire is fried to surperficial micro-yellow, takes out, cools, be placed in mortar porphyrize, crosses 160 mesh sieves;
(2) Carnis Pseudosciaenae is slaughtered, scrape one time with hilt fish skin, stick with paste on fish skin with Semen Glycines powder, rub 4 minutes, clean, be placed in pot, add Rhizoma Zingiberis Recens, Herba Alii fistulosi, cooking wine, add decocting in water 15 minutes, add Radix Cissi Kerrii, Rhizoma amorphophalli, Tremella, Semen Gleditsiae and Radix Morindae Officinalis, continue to boil 35 minutes, filter, obtain filtrate 1, continue to add decocting in water 25 minutes, filter, obtain filtrate 2;
(3) filtrate 1 and filtrate 2 are mixed, add step (1) gained medicated powder, be concentrated into 1/2 of original volume;
(4) Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis are smashed, are placed in container, add white vinegar (consumption be Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis gross mass 33%), moistening 9 hours;
(5) Fructus Mahoniae, Cortex Cinnamomi Burmannii, Herba Eragrostidis pilosae, Aleuritopteris farinsa (Forsk.) Fee and Herba Sedi are placed in marmite, soak 25 minutes, add step (4) gains, decoct twice, each decoction 40 minutes, merging filtrate;
(6) by step (3) gained concentrated solution and step (5) gained filtrate mixing, hold over night, filter, be concentrated into relative density 1.25(25 DEG C) thick paste, dry, pulverize, cross 190 mesh sieves, make capsule (0.5g/ grain).
Instructions of taking: each 2-3 grain, every day 2 times, 12 days courses for the treatment of.
test example:in order to verify a kind of curative effect of preventing and treating the Chinese medicine composition (embodiment 5) of the brain cancer of the present invention, do contrast test in November ,-2013 in April, 2011:
General data: screening 250 routine brain cancer patient, wherein minimal ages 41 years old, max age 75 years old, 53.7 years old mean age.Be divided into experimental group and matched group two groups (wherein experimental group 150 people, matched group 100 people) at random, two groups are compared there was no significant difference, have comparability in sex, age, the course of disease, state of an illness scoring etc.
Diagnostic criteria: 1. nausea and vomiting, headache, headache multidigit, in forehead and temples, is the aggravation of persistent headache paroxysmal, and headache in morning of being everlasting is heavier.2. brain CT shows tumor focus, finds that there is cancerous cell exist through tissue examination.3. spirit and disturbance of consciousness and other symptoms: dizziness, diplopia, temporary amaurosis, damping off, confusion, spirit uneasiness or indifferent, can epilepsy be there is, even go into a coma.4. changes of vital signs: when moderate and severe acute increased intracranial pressure, often causes breathing, pulse, slows down, and blood pressure raises.
Usage and dosage: experimental group takes a kind of Chinese medicine composition preventing and treating the brain cancer of the present invention, each serving with 2, every day 2 times, 12 days courses for the treatment of; Matched group takes other medicine (as semustine capsule, Nimustine etc.), wherein, and semustine capsule: the oral 100-200mg/m of this product
2, decoction being taken at a draught, every 6-8 week once, takes together with antiemetic, sleeping pill before sleeping.Nimustine: usually, the ratio that this agent is dissolved in water for injection 1ml in every 5mg dissolves following dosage, for vein or artery administration, in Nimustine, by body weight administration, give 2-3mg/kg 1 time, thereafter according to hemogram drug withdrawal 4-6 week, administration again, so repeatedly, until the effect of clinical satisfaction.
Criterion of therapeutical effect: cure: the phenomenons such as dizziness headache, health are weak are for disappearing, and appetite, sleep are normal, cell carcinoma tumor foci disappearance, and do not recur at least two years; Effective: the symptoms such as dizziness headache, health are weak alleviate or partial disappearance, and cancerous cell obviously reduces, tumor focus reduces; Invalid: the diseases such as dizziness headache, health are weak occur increasing the weight of sign without obviously alleviating the even state of an illness.
Adopt the matched group of other drug and take a kind of Comparison of therapeutic of preventing and treating the experimental group of the Chinese medicine composition of the brain cancer of the present invention, result is as shown in table 1:
Table 1
efficacy analysis:as can be seen from Table 1, take a kind of inefficiency of preventing and treating the Chinese medicine composition of the brain cancer of the present invention and be only 4%, cure rate is up to 67.33%, effective percentage is up to 96%, and adopting the inefficiency had up to 24% of other treatment scheme, cure rate only reaches 35%, and effective percentage is also only 76%.Experiment shows that a kind of Chinese medicine composition preventing and treating the brain cancer of the present invention is compared with other drug, and evident in efficacy, cure rate is high, and inefficiency is low.Selected by Chinese medicine composition of the present invention, medical material compatibility is suitable, and the treatment brain cancer is evident in efficacy, takes stopgap measures and effects a permanent cure, reach the object for the treatment of both the principal and secondary aspects of a disease, not easily recur more.
Finally it should be noted that, embodiment is the detailed description of the invention of optimum of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (10)
1. prevent and treat a Chinese medicine composition for the brain cancer, it is characterized in that, take off the primary raw material stating weight proportion and be prepared from: Cordyceps 10-16 part; Fructus Mahoniae 8-13 part; Cortex Cinnamomi Burmannii 6-9 part; Radix Ranunculi Ternati 9-15 part; Radix Cissi Kerrii 7-13 part; Rhizoma amorphophalli 6-12 part; Herba Eragrostidis pilosae 10-14 part; Carnis Pseudosciaenae 12-18 part; Tremella 9-16 part; Aleuritopteris farinsa (Forsk.) Fee 8-14 part; Herba Sedi 9-13 part; Semen Gleditsiae 6-11 part; Radix Morindae Officinalis 8-12 part; Oil head grass 10-16 part; Radix Fortunellae Margaritae 8-15 part; Herba Epilobii Himalayensis 9-14 part.
2. Chinese medicine composition according to claim 1, is characterized in that, takes off the primary raw material stating weight proportion and is prepared from: Cordyceps 12-14 part; Fructus Mahoniae 10-12 part; Cortex Cinnamomi Burmannii 7-8 part; Radix Ranunculi Ternati 11-13 part; Radix Cissi Kerrii 9-11 part; Rhizoma amorphophalli 8-10 part; Herba Eragrostidis pilosae 11-13 part; Carnis Pseudosciaenae 14-16 part; Tremella 12-14 part; Aleuritopteris farinsa (Forsk.) Fee 10-12 part; Herba Sedi 10-12 part; Semen Gleditsiae 8-10 part; Radix Morindae Officinalis 9-11 part; Oil head grass 12-14 part; Radix Fortunellae Margaritae 11-13 part; Herba Epilobii Himalayensis 11-13 part.
3. Chinese medicine composition according to claim 1, is characterized in that, takes off the primary raw material stating weight proportion and is prepared from: Cordyceps 13 parts; Fructus Mahoniae 11 parts; Cortex Cinnamomi Burmannii 7.5 parts; Radix Ranunculi Ternati 12 parts; Radix Cissi Kerrii 10 parts; Rhizoma amorphophalli 9 parts; Herba Eragrostidis pilosae 12 parts; Carnis Pseudosciaenae 15 parts; 13 parts, Tremella; Aleuritopteris farinsa (Forsk.) Fee 11 parts; Herba Sedi 11 parts; Semen Gleditsiae 9 parts; Radix Morindae Officinalis 10 parts; Oil head grass 13 parts; Radix Fortunellae Margaritae 12 parts; Herba Epilobii Himalayensis 12 parts.
4., according to the arbitrary described Chinese medicine composition of claim 1-3, it is characterized in that: the preparation method of described decoction, step is as follows:
(1) pot is burnt heat, add edible oil, after oily heat, add Cordyceps, slow fire is fried to surperficial micro-yellow, takes out, cools, be placed in mortar porphyrize, crosses 140-180 mesh sieve (preferred cross 150-170 mesh sieve, be more preferably 160 mesh sieves);
(2) Carnis Pseudosciaenae is slaughtered, carefully scrape one time with hilt fish skin, stick with paste on fish skin with Semen Glycines powder, rub 3-5 minute, clean, stripping and slicing, be placed in pot, add Rhizoma Zingiberis Recens, Herba Alii fistulosi, cooking wine, add decocting in water 10-20 minute, add Radix Cissi Kerrii, Rhizoma amorphophalli, Tremella, Semen Gleditsiae and Radix Morindae Officinalis, continue to boil 30-40 minute, filter, obtain filtrate 1, continue to add decocting in water 20-30 minute, filter, obtain filtrate 2;
(3) filtrate 1 and filtrate 2 are mixed, add step (1) gained medicated powder, be concentrated into 1/2 of original volume;
(4) Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis are smashed, be placed in container, add white vinegar, moistening 8-10 hour;
(5) Fructus Mahoniae, Cortex Cinnamomi Burmannii, Herba Eragrostidis pilosae, Aleuritopteris farinsa (Forsk.) Fee and Herba Sedi are placed in marmite, soak 20-30 minute, add step (4) gains, decoct twice, each decoction 30-50 minute (preferably each decoction 35-45 minute, is more preferably each decoction 40 minutes), merging filtrate;
(6) by step (3) gained concentrated solution and the mixing of step (5) gained filtrate, add correctives, hold over night, filter, sterile packaged.
5. the preparation method of Chinese medicine composition according to claim 4, it is characterized in that: the consumption of the preferred white vinegar of step (4) is the 30%-35% of Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis gross mass, the consumption being more preferably white vinegar be Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis gross mass 33%.
6., according to the arbitrary described Chinese medicine composition of claim 1-3, it is characterized in that: the preparation method of described granule, step is as follows:
(1) pot is burnt heat, add edible oil, after oily heat, add Cordyceps, slow fire is fried to surperficial micro-yellow, takes out, cools, be placed in mortar porphyrize, crosses 140-180 mesh sieve (preferred cross 150-170 mesh sieve, be more preferably 160 mesh sieves);
(2) Carnis Pseudosciaenae is slaughtered, scrape one time with hilt fish skin, stick with paste on fish skin with Semen Glycines powder, rub 3-5 minute, clean, be placed in pot, add Rhizoma Zingiberis Recens, Herba Alii fistulosi, cooking wine, add decocting in water 10-20 minute, add Radix Cissi Kerrii, Rhizoma amorphophalli, Tremella, Semen Gleditsiae and Radix Morindae Officinalis, continue to boil 30-40 minute, filter, obtain filtrate 1, continue to add decocting in water 20-30 minute, filter, obtain filtrate 2;
(3) filtrate 1 and filtrate 2 are mixed, add step (1) gained medicated powder, be concentrated into 1/2 of original volume;
(4) Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis are smashed, be placed in container, (consumption of preferred white vinegar is the 30%-35% of Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis gross mass to add white vinegar, the consumption being more preferably white vinegar be Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis gross mass 33%), moistening 8-10 hour;
(5) Fructus Mahoniae, Cortex Cinnamomi Burmannii, Herba Eragrostidis pilosae, Aleuritopteris farinsa (Forsk.) Fee and Herba Sedi are placed in marmite, soak 20-30 minute, add step (4) gains, decoct twice, each decoction 30-50 minute (preferably each decoction 35-45 minute, is more preferably each decoction 40 minutes), merging filtrate;
(6) by step (3) gained concentrated solution and the mixing of step (5) gained filtrate, hold over night, filter, be concentrated into the thick paste of relative density 1.10-1.20, make uniform fine particle, be aided with pharmaceutically acceptable carrier package, the quality of every parcel is 6g.
7. the preparation method of Chinese medicine composition according to claim 6, is characterized in that: step (6) is preferably concentrated into the thick paste of relative density 1.13-1.17, is more preferably the thick paste being concentrated into relative density 1.15.
8., according to the arbitrary described Chinese medicine composition of claim 1-3, it is characterized in that: the preparation method of described concentrated pill, step is as follows:
(1) pot is burnt heat, add edible oil, after oily heat, add Cordyceps, slow fire is fried to surperficial micro-yellow, takes out, cools, be placed in mortar porphyrize, crosses 140-180 mesh sieve (preferred cross 150-170 mesh sieve, be more preferably 160 mesh sieves);
(2) Carnis Pseudosciaenae is slaughtered, scrape one time with hilt fish skin, stick with paste on fish skin with Semen Glycines powder, rub 3-5 minute, clean, be placed in pot, add Rhizoma Zingiberis Recens, Herba Alii fistulosi, cooking wine, add decocting in water 10-20 minute, add Radix Cissi Kerrii, Rhizoma amorphophalli, Tremella, Semen Gleditsiae and Radix Morindae Officinalis, continue to boil 30-40 minute, filter, obtain filtrate 1, continue to add decocting in water 20-30 minute, filter, obtain filtrate 2;
(3) filtrate 1 and filtrate 2 are mixed, add step (1) gained medicated powder, be concentrated into 1/2 of original volume;
(4) Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis are smashed, be placed in container, (consumption of preferred white vinegar is the 30%-35% of Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis gross mass to add white vinegar, the consumption being more preferably white vinegar be Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis gross mass 33%), moistening 8-10 hour;
(5) Fructus Mahoniae, Cortex Cinnamomi Burmannii, Herba Eragrostidis pilosae, Aleuritopteris farinsa (Forsk.) Fee and Herba Sedi are placed in marmite, soak 20-30 minute, add step (4) gains, decoct twice, each decoction 30-50 minute (preferably each decoction 35-45 minute, is more preferably each decoction 40 minutes), merging filtrate;
(6) by step (3) gained concentrated solution and the mixing of step (5) gained filtrate, hold over night, filter, the thick paste being concentrated into relative density 1.10-1.20 (is preferably concentrated into the thick paste of relative density 1.13-1.17, be more preferably the thick paste being concentrated into relative density 1.15), make concentrated pill (preferred diameter is 3-5mm, and being more preferably diameter is 4mm), sterile packaged.
9., according to the arbitrary described Chinese medicine composition of claim 1-3, it is characterized in that: the preparation method of described tablet, step is as follows:
(1) pot is burnt heat, add edible oil, after oily heat, add Cordyceps, slow fire is fried to surperficial micro-yellow, takes out, cools, be placed in mortar porphyrize, crosses 140-180 mesh sieve (preferred cross 150-170 mesh sieve, be more preferably 160 mesh sieves);
(2) Carnis Pseudosciaenae is slaughtered, scrape one time with hilt fish skin, stick with paste on fish skin with Semen Glycines powder, rub 3-5 minute, clean, be placed in pot, add Rhizoma Zingiberis Recens, Herba Alii fistulosi, cooking wine, add decocting in water 10-20 minute, add Radix Cissi Kerrii, Rhizoma amorphophalli, Tremella, Semen Gleditsiae and Radix Morindae Officinalis, continue to boil 30-40 minute, filter, obtain filtrate 1, continue to add decocting in water 20-30 minute, filter, obtain filtrate 2;
(3) filtrate 1 and filtrate 2 are mixed, add step (1) gained medicated powder, be concentrated into 1/2 of original volume;
(4) Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis are smashed, be placed in container, (consumption of preferred white vinegar is the 30%-35% of Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis gross mass to add white vinegar, the consumption being more preferably white vinegar be Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis gross mass 33%), moistening 8-10 hour;
(5) Fructus Mahoniae, Cortex Cinnamomi Burmannii, Herba Eragrostidis pilosae, Aleuritopteris farinsa (Forsk.) Fee and Herba Sedi are placed in marmite, soak 20-30 minute, add step (4) gains, decoct twice, each decoction 30-50 minute (preferably each decoction 35-45 minute, is more preferably each decoction 40 minutes), merging filtrate;
(6) by step (3) gained concentrated solution and the mixing of step (5) gained filtrate, hold over night, filter, the thick paste being concentrated into relative density 1.10-1.20 (is preferably concentrated into the thick paste of relative density 1.13-1.17, be more preferably the thick paste being concentrated into relative density 1.15), make tablet.
10., according to the arbitrary described Chinese medicine composition of claim 1-3, it is characterized in that: the preparation method of described capsule, step is as follows:
(1) pot is burnt heat, add edible oil, after oily heat, add Cordyceps, slow fire is fried to surperficial micro-yellow, takes out, cools, be placed in mortar porphyrize, crosses 140-180 mesh sieve (preferred cross 150-170 mesh sieve, be more preferably 160 mesh sieves);
(2) Carnis Pseudosciaenae is slaughtered, scrape one time with hilt fish skin, stick with paste on fish skin with Semen Glycines powder, rub 3-5 minute, clean, be placed in pot, add Rhizoma Zingiberis Recens, Herba Alii fistulosi, cooking wine, add decocting in water 10-20 minute, add Radix Cissi Kerrii, Rhizoma amorphophalli, Tremella, Semen Gleditsiae and Radix Morindae Officinalis, continue to boil 30-40 minute, filter, obtain filtrate 1, continue to add decocting in water 20-30 minute, filter, obtain filtrate 2;
(3) filtrate 1 and filtrate 2 are mixed, add step (1) gained medicated powder, be concentrated into 1/2 of original volume;
(4) Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis are smashed, be placed in container, (consumption of preferred white vinegar is the 30%-35% of Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis gross mass to add white vinegar, the consumption being more preferably white vinegar be Radix Ranunculi Ternati, oil head grass, Radix Fortunellae Margaritae and Herba Epilobii Himalayensis gross mass 33%), moistening 8-10 hour;
(5) Fructus Mahoniae, Cortex Cinnamomi Burmannii, Herba Eragrostidis pilosae, Aleuritopteris farinsa (Forsk.) Fee and Herba Sedi are placed in marmite, soak 20-30 minute, add step (4) gains, decoct twice, each decoction 30-50 minute (preferably each decoction 35-45 minute, is more preferably each decoction 40 minutes), merging filtrate;
(6) by step (3) gained concentrated solution and the mixing of step (5) gained filtrate, hold over night, filter, be concentrated into the thick paste (be preferably concentrated into the thick paste of relative density 1.23-1.27, be more preferably the thick paste being concentrated into relative density 1.25) of relative density 1.20-1.30, dry, pulverize, cross 180-200 mesh sieve, make capsule (preferred 0.4-0.6g/ grain, is more preferably 0.5g/ grain).
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| CN1943778A (en) * | 2006-10-25 | 2007-04-11 | 薛忠 | The mixture of cobra venom and Chinese medical herb extract and its application |
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