CN104606370A - Medicine composition with effect of improving male sexual functions and preparation method thereof - Google Patents

Medicine composition with effect of improving male sexual functions and preparation method thereof Download PDF

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CN104606370A
CN104606370A CN201510075604.7A CN201510075604A CN104606370A CN 104606370 A CN104606370 A CN 104606370A CN 201510075604 A CN201510075604 A CN 201510075604A CN 104606370 A CN104606370 A CN 104606370A
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王学兵
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Abstract

The invention discloses a medicine composition with the effect of improving male sexual functions. The medicine composition is mainly prepared from the following raw material medicines in parts by weight: 12-18 parts of Chinese angelica, 9-21 parts of barbary wolfberry fruit, 10-15 parts of Chinese dodder seed, 12-16 parts of largetrifoliolious bugbane rhizome, 11-15 parts of herb of russian boschniakia, 13-17 parts of common macrocarpium fruit, 14-19 parts of suberect spatholobus stem, 10-15 parts of root of largeleaf gentian, 11-14 parts of oyster shell, 12-20 parts of herb of shorthorned epimedium, 10-16 parts of weeping forsythia capsule, 14-19 parts of pollen, 9-17 parts of hairy antler, 9-16 parts of dogbane leaf, 11-19 parts of Chinese wolfberry root-bark and 10-18 parts of fortune eupatorium herb. Raw materials adopted by the medicine composition disclosed by the invention are traditional Chinese medicine materials, so that the medicine composition cannot cause obvious toxic or side effects and can be safely taken; the medicine composition can be used for improving the male sexual functions by regulating body functions, and is more effective and more durable; and the medicine composition can be prepared into a plurality of dosage forms, is convenient to carry, is beneficial for patients to take, also is stable in effective components, and ensures that the curative effect is reliable.

Description

There is the drug regimen and preparation method that improve male sexual function
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to and a kind of there is the drug regimen and preparation method that improve male sexual function.
Background technology
Male sexual function, the healthy reproduction of the male referred to and sexual function ability thereof.Man's sexual activity is a complicated physiological process, will have been come by a series of trained reflex and unconditioned reflex.The normal sexual function of male needs the cooperation of sound sexual function maincenter industry conduction, sex hormone regulation and genitals.Wherein there is dysfunction or disappearance in any organ, any link, and patient all can be caused when sexual life to occur uncomfortable reaction, thus inhibition desire, produce male sexual disorder.Male sexual disorder refers to and can not carry out normal sexual behaviour, or can not obtain satisfied in normal sexual behaviour.Sexual dysfunction majority does not all have organic disease, and that is sexual organ does not have exception or pathological changes, but cause because of psychological factor.Thus in sexology, sexual psychology dysfunction is usually called.Sexual dysfunction is generally divided into psychological sexual dysfunction and organic sexual dysfunction.The male sexual disorder cause of disease is very complicated, is not only caused by functional disorder, truly has many organic diseases and cause sexual dysfunction.Publication number CN 102579703 A(application number 201210067190.X) Chinese patent literature disclose one and improve male's sexual product and preparation method thereof, raw material comprises: Cordyceps extract 10-20, Fructus Tribuli extract 10-20, Fructus Vitis viniferae extract 20-30, Pulp Citrulli extract 5-15, Stichopus japonicus extract 8-15, Radix Rhodiolae extract 5-15, Herba Epimedii extract 10-20.Publication number CN 102908417 A(application number 201210368549.7) Chinese patent literature disclose a kind of Chinese medicine for the treatment of impotence, raw material consists of Ramulus Cinnamomi 10-14, Herba Epimedii 1-5, Oletum Trogopterori 8-12, CUIYUNCAO 6-10, Os Draconis 13-17, Rhizoma Drynariae 13-17, Scolopendra 8-12, Setaria palmifolia 6-10, Radix Aconiti Lateralis Preparata 1-5, Herba Gerberae Piloselloidis 1-5, Radix Ginseng Rubra 13-17, Radix Paeoniae Alba 6-10, Caulis Spatholobi 8-12.Publication number CN 103989166 A(application number 201410195045.9) Chinese patent literature disclose a kind of health food improving male's sexual, formulated by Herba Epimedii 15-300, Radix Morindae Officinalis 15-300, Radix Astragali 20-300, Radix Codonopsis 15-200, Radix Achyranthis Bidentatae 10-100, Rhizoma Polygonati 20-300, Radix Rehmanniae 20-200, Radix Rehmanniae Preparata 30-300, Radix Paeoniae Alba 20-200 and Rhizoma Cyperi 10-100.
Though medea on the market can improve male sexual function, but the effect that these medeas are only just temporary transient, and by improving male body function, can not improve its sexual function, some even can damage the health of male, there is great hidden danger.China's traditional medicine, pure natural animals and plants material obtains, safe and reliable, and effectively can improve function of human body, therefore, is necessary to develop a kind of drug regimen improving male sexual function from Chinese medicine and pharmacy aspect.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide a kind of prepare simple, taking convenience there is the drug regimen and preparation method that improve male sexual function.
Technical scheme of the present invention is:
There is the drug regimen improving male sexual function, be prepared from primarily of following bulk drugs, be weight portion: Radix Angelicae Sinensis 12-18, Fructus Lycii 9-21, Semen Cuscutae 10-15, Rhizoma Cimicifugae 12-16, Herba Boschniakiae Rossicae 11-15, Fructus Corni 13-17, Caulis Spatholobi 14-19, Radix Gentianae Macrophyllae 10-15, Concha Ostreae 11-14, Herba Epimedii 12-20, Fructus Forsythiae 10-16, pollen 14-19, Cornu Cervi Pantotrichum 9-17, Herba Apocyni veneti 9-16, Cortex Lycii 11-19, Herba Eupatorii 10-18.
In preferred scheme, Radix Angelicae Sinensis 13-17, Fructus Lycii 12-18, Semen Cuscutae 11-14, Rhizoma Cimicifugae 13-15, Herba Boschniakiae Rossicae 12-14, Fructus Corni 14-16, Caulis Spatholobi 15-18, Radix Gentianae Macrophyllae 11-14, Concha Ostreae 12-13, Herba Epimedii 14-18, Fructus Forsythiae 12-14, pollen 15-18, Cornu Cervi Pantotrichum 11-15, Herba Apocyni veneti 11-14, Cortex Lycii 13-17, Herba Eupatorii 12-16.
Be more preferably, Radix Angelicae Sinensis 15, Fructus Lycii 15, Semen Cuscutae 12.5, Rhizoma Cimicifugae 14, Herba Boschniakiae Rossicae 13, Fructus Corni 15, Caulis Spatholobi 16.5, Radix Gentianae Macrophyllae 12.5, Concha Ostreae 12.5, Herba Epimedii 16, Fructus Forsythiae 13, pollen 16.5, Cornu Cervi Pantotrichum 13, Herba Apocyni veneti 12.5, Cortex Lycii 15, Herba Eupatorii 14.
The described preparation method with the drug regimen decoction improving male sexual function is:
(1) Semen Cuscutae yellow wine is boiled to snuff, take out, mash, add face and Mel and even, make cake, dry;
(2) get Cortex Lycii to clean, use rice water saturates, pull out, put into tank and obturage, then tank is put into pot and boil 3-5 hour (preferred, put into pot and boil 4 hours), take out, dry;
(3) Cornu Cervi Pantotrichum is burned remove floss, scraping, be split into fragment, mix thoroughly with vinegar, put into pot and steam 20-30 minute (preferred, to put into pot and steam 25 minutes), take out, put into frying pan, fried dry, take out, be ground into fine powder;
(4) Concha Ostreae is scrubbed clean, break into pieces, put into marmite, boil 40 minutes, Guan Huo, add Radix Angelicae Sinensis, Fructus Lycii, Rhizoma Cimicifugae, Herba Boschniakiae Rossicae, Fructus Corni, Caulis Spatholobi, Radix Gentianae Macrophyllae, Herba Epimedii, Fructus Forsythiae, Herba Eupatorii and step (1) (2) made crude drug, soak 10 minutes, after being heated to boiling, turning little fire and decoct, Guan Huohou adds Herba Apocyni veneti immediately, stir, add a cover, place after 20 minutes, filter, collect filtrate;
(5) pollen is pulverized, join together with step (3) made fine powder in step (4) made filtrate, stir evenly, obtain decoction.
The described preparation method with the drug regimen decoction improving male sexual function, step (4) turn little fire decocts 20-40 minute, and (preferred, 25-35 minute decocted by a turn little fire; Be more preferably, turn little fire and decoct 30 minutes).
The preparation method of described pill is:
(1) Semen Cuscutae yellow wine is boiled to snuff, take out, mash, add face and Mel and even, make cake, dry;
(2) get Cortex Lycii to clean, use rice water saturates, pull out, put into tank and obturage, then tank is put into pot and boil 3-5 hour (preferred, put into pot and boil 4 hours), take out, dry;
(3) Cornu Cervi Pantotrichum is burned remove floss, scraping, be split into fragment, mix thoroughly with vinegar, put into pot and steam 20-30 minute (preferred, to put into pot and steam 25 minutes), take out, put into frying pan, fried dry, take out, be ground into fine powder;
(4) by Radix Angelicae Sinensis, Rhizoma Cimicifugae, Fructus Corni, Radix Gentianae Macrophyllae, Concha Ostreae, Herba Epimedii and Fructus Forsythiae decontamination, slightly soak, put into the micro-stir-fry of pot, taking-up is dried in the air cool, pulverizes and sieves, obtain medicated powder with pollen, Fructus Lycii together with step (1) (2) made crude drug;
(5) Herba Boschniakiae Rossicae, Caulis Spatholobi, Herba Apocyni veneti and Herba Eupatorii are picked clean impurity, put into marmite and boil 20 minutes, filter, collect filtrate, heating is concentrated, mixes, and add pharmaceutical excipients with step (3) (4) made fine powder and medicated powder, generally makes ball, obtains pill.
The described preparation method with the drug regimen pill improving male sexual function, step (4) was pulverized 100-160 mesh sieve and (preferably, was pulverized 120-140 mesh sieve; Be more preferably, pulverized 130 mesh sieves).
The preparation method of described tablet is:
(1) Semen Cuscutae yellow wine is boiled to snuff, take out, mash, add face and Mel and even, make cake, dry;
(2) get Cortex Lycii to clean, use rice water saturates, pull out, put into tank and obturage, then tank is put into pot and boil 3-5 hour (preferred, put into pot and boil 4 hours), take out, dry;
(3) Cornu Cervi Pantotrichum is burned remove floss, scraping, be split into fragment, mix thoroughly with vinegar, put into pot and steam 20-30 minute (preferred, to put into pot and steam 25 minutes), take out, put into frying pan, fried dry, take out, be ground into fine powder;
(4) by Radix Angelicae Sinensis, Fructus Lycii, Rhizoma Cimicifugae, Fructus Corni, Radix Gentianae Macrophyllae, Concha Ostreae, Herba Epimedii, Fructus Forsythiae and pollen decontamination, slightly soak, put into the micro-stir-fry of pot, taking-up is dried in the air cool, the 100-160 mesh sieve that pulverizes and sieves together with step (1) (2) made crude drug (preferably, pulverized 120-140 mesh sieve; Be more preferably, pulverized 130 mesh sieves), obtain medicated powder;
(5) Herba Boschniakiae Rossicae, Caulis Spatholobi, Herba Apocyni veneti and Herba Eupatorii are picked clean impurity, put into marmite and boil 20 minutes, filter, collect filtrate, heating is concentrated, mix with (4) made medicated powder, lyophilization, pulverizes, then mixes with step (3) made fine powder, obtained mixed powder, is finally pressed into circular or other forms of tablet dosage form according to the preparation for processing of tablet.
The described preparation method with the drug regimen tablet improving male sexual function, in step (5) made tablet, the amount of mixed powder contained by every sheet is that 0.2-0.3g(is preferred, and contained by every sheet, the amount of mixed powder is 0.25g).
The preparation method of described granule is:
(1) Semen Cuscutae yellow wine is boiled to snuff, take out, mash, add face and Mel and even, make cake, dry, pulverize, obtain medicated powder;
(2) get Cortex Lycii to clean, use rice water saturates, pull out, put into tank and obturage, then tank is put into pot boil, rear taking-up, dries;
(3) Cornu Cervi Pantotrichum is burned remove floss, scraping, be split into fragment, mix thoroughly with vinegar, put into pot and steam 20-30 minute (preferred, to put into pot and steam 25 minutes), take out, put into frying pan, fried dry, take out, be ground into fine powder together with pollen;
(4) Concha Ostreae is scrubbed clean, break into pieces, put into marmite, boil 40 minutes, Guan Huo, add Radix Angelicae Sinensis, Fructus Lycii, Rhizoma Cimicifugae, Herba Boschniakiae Rossicae, Fructus Corni, Caulis Spatholobi, Radix Gentianae Macrophyllae, Herba Epimedii, Fructus Forsythiae, Herba Eupatorii and step (2) made crude drug, soak 10 minutes, after being heated to boiling, a turn little fire decocts 20-40 minute, and (preferred, 25-35 minute decocted by a turn little fire; Be more preferably, turn little fire and decoct 30 minutes), Guan Huohou puts into Herba Apocyni veneti immediately, stirs, and adds a cover, and places after 20 minutes, filters, and collect filtrate, filtering residue is for subsequent use;
(5) by step (4) remaining filtering residue, add water and again decoct 30 minutes, filter, merge with step (4) made filtrate, stir evenly, lyophilization, pulverize, mix with step (1) (3) made medicated powder and fine powder, add pharmaceutical excipients, make soft material, cross 12 mesh sieve granulate, 60 DEG C of dryings, granulate, obtains granule.
The described preparation method with the drug regimen granule improving male sexual function, step (2) is put into pot and is boiled 3-5 hour (preferred, to put into pot and boil 4 hours).
Provided by the invention have the drug regimen scientific formula improving male sexual function, and preparation method is simple, products obtained therefrom taking convenience.In addition, excellent results of the present invention also shows:
1, the present invention is raw materials used is Chinese medicine material, without obvious toxic-side effects, can relievedly take;
2, this prescription is by regulating physical function, improves male sexual function, more effectively, more lasting;
3, the present invention can be prepared into multiple dosage form, easy to carry, is conducive to taking of patient, and wherein stable effective ingredients, ensure that curative effect is reliable.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1there is the drug regimen improving male sexual function, be prepared from (every part of 10g) primarily of following bulk drugs: Radix Angelicae Sinensis 12 parts, Fructus Lycii 9 parts, Semen Cuscutae 10 parts, Rhizoma Cimicifugae 12 parts, Herba Boschniakiae Rossicae 11, Fructus Corni 13 parts, Caulis Spatholobi 14 parts, Radix Gentianae Macrophyllae 10 parts, Concha Ostreae 11 parts, Herba Epimedii 12 parts, Fructus Forsythiae 10 parts, Pollen Codonopsis 14 parts, 9 parts, Cornu Cervi Pantotrichum, Herba Apocyni veneti 9 parts, Cortex Lycii 11 parts, Herba Eupatorii 10 parts.
The above-mentioned preparation method with the drug regimen decoction improving male sexual function is:
(1) Semen Cuscutae yellow wine is boiled to snuff, take out, mash, add face and Mel and even, make cake, dry;
(2) get Cortex Lycii to clean, use rice water saturates, pull out, put into tank and obturage, then tank is put into pot and boil 4 hours, take out, dry;
(3) Cornu Cervi Pantotrichum is burned remove floss, scraping, be split into fragment, mix thoroughly with vinegar, put into pot and steam 25 minutes, take out, put into frying pan, fried dry, take out, be ground into fine powder;
(4) Concha Ostreae is scrubbed clean, break into pieces, put into marmite, boil 40 minutes, Guan Huo, add Radix Angelicae Sinensis, Fructus Lycii, Rhizoma Cimicifugae, Herba Boschniakiae Rossicae, Fructus Corni, Caulis Spatholobi, Radix Gentianae Macrophyllae, Herba Epimedii, Fructus Forsythiae, Herba Eupatorii and step (1) (2) made crude drug, soak 10 minutes, after being heated to boiling, turning little fire and decoct 30 minutes, Guan Huohou adds Herba Apocyni veneti immediately, stir, add a cover, place after 20 minutes, filter, collect filtrate;
(5) pollen is pulverized, join together with step (3) made fine powder in step (4) made filtrate, stir evenly, obtain decoction.
embodiment 2there is the drug regimen improving male sexual function, be prepared from (every part of 10g) primarily of following bulk drugs: Radix Angelicae Sinensis 18 parts, Fructus Lycii 21 parts, Semen Cuscutae 15 parts, Rhizoma Cimicifugae 16 parts, Herba Boschniakiae Rossicae 15, Fructus Corni 17 parts, Caulis Spatholobi 19 parts, Radix Gentianae Macrophyllae 15 parts, Concha Ostreae 14 parts, Herba Epimedii 20 parts, Fructus Forsythiae 16 parts, Fructus Schisandrae Chinensis pollen 19 parts, 17 parts, Cornu Cervi Pantotrichum, Herba Apocyni veneti 16 parts, Cortex Lycii 19 parts, Herba Eupatorii 18 parts.
The preparation method with the drug regimen pill improving male sexual function is:
(1) Semen Cuscutae yellow wine is boiled to snuff, take out, mash, add face and Mel and even, make cake, dry;
(2) get Cortex Lycii to clean, use rice water saturates, pull out, put into tank and obturage, then tank is put into pot and boil 4 hours, take out, dry;
(3) Cornu Cervi Pantotrichum is burned remove floss, scraping, be split into fragment, mix thoroughly with vinegar, put into pot and steam 25 minutes, take out, put into frying pan, fried dry, take out, be ground into fine powder;
(4) by Radix Angelicae Sinensis, Rhizoma Cimicifugae, Fructus Corni, Radix Gentianae Macrophyllae, Concha Ostreae, Herba Epimedii and Fructus Forsythiae decontamination, slightly soak, put into the micro-stir-fry of pot, taking-up is dried in the air cool, pulverized 130 mesh sieves, and obtained medicated powder with pollen, Fructus Lycii together with step (1) (2) made crude drug;
(5) Herba Boschniakiae Rossicae, Caulis Spatholobi, Herba Apocyni veneti and Herba Eupatorii are picked clean impurity, put into marmite and boil 20 minutes, filter, collect filtrate, heating is concentrated, mixes, and add pharmaceutical excipients with step (3) (4) made fine powder and medicated powder, generally makes ball, obtains pill.
Model case: xxx, man, 36 years old.Nearly half a year without the appearance not ejaculation liquid of obvious inducement, after taken kidney tonifying, essence replenishing folk prescription, do not take a favorable turn, time sense bitter taste xerostomia, constipation, urine is partially yellow, sleep and diet without exception, red tongue BOHUANG greasy fur, deep pulse stringy and rapid pulse, by asking about, finding the present inventor, being diagnosed as sexual disorder on inspection.
Take the present embodiment gained and there is the drug regimen pill improving male sexual function, every day 2 times, each 4, warm water delivery service, 20 days courses for the treatment of.After taking one month, a small amount of seminal fluid can be had to discharge, continue to take two courses for the treatment of, can normal ejaculation, patient fully recovers, and taking period patient does not have malaise symptoms.
embodiment 3there is the drug regimen improving male sexual function, be prepared from (every part of 10g) primarily of following bulk drugs: Radix Angelicae Sinensis 13 parts, Fructus Lycii 12 parts, Semen Cuscutae 11 parts, Rhizoma Cimicifugae 13 parts, Herba Boschniakiae Rossicae 12 parts, Fructus Corni 14 parts, Caulis Spatholobi 15 parts, Radix Gentianae Macrophyllae 11 parts, Concha Ostreae 12 parts, Herba Epimedii 14 parts, Fructus Forsythiae 12 parts, Pollen Brassicae campestris 15 parts, 11 parts, Cornu Cervi Pantotrichum, Herba Apocyni veneti 11 parts, Cortex Lycii 13 parts, Herba Eupatorii 12 parts.
The preparation method with the drug regimen tablet improving male sexual function is:
(1) Semen Cuscutae yellow wine is boiled to snuff, take out, mash, add face and Mel and even, make cake, dry;
(2) get Cortex Lycii to clean, use rice water saturates, pull out, put into tank and obturage, then tank is put into pot and boil 4 hours, take out, dry;
(3) Cornu Cervi Pantotrichum is burned remove floss, scraping, be split into fragment, mix thoroughly with vinegar, put into pot and steam 25 minutes, take out, put into frying pan, fried dry, take out, be ground into fine powder;
(4) by Radix Angelicae Sinensis, Fructus Lycii, Rhizoma Cimicifugae, Fructus Corni, Radix Gentianae Macrophyllae, Concha Ostreae, Herba Epimedii, Fructus Forsythiae and pollen decontamination, slightly soak, put into the micro-stir-fry of pot, take out and dry in the air cool, pulverize and sieve 130 mesh sieves together with step (1) (2) made crude drug, obtain medicated powder;
(5) Herba Boschniakiae Rossicae, Caulis Spatholobi, Herba Apocyni veneti and Herba Eupatorii are picked clean impurity, put into marmite and boil 20 minutes, filter, collect filtrate, heating is concentrated, mix with (4) made medicated powder, lyophilization, pulverizes, then mixes with step (3) made fine powder, obtained mixed powder, is finally pressed into circular or other forms of tablet dosage form (contained by every sheet, the amount of mixed powder is 0.25g) according to the preparation for processing of tablet.
Model case: xxx, man, 26 years old.Main suit: since marriage, normal sense interior-heat is irritated, lower cloudy moist, itch, before half a year, self-inductor is sleepy idle; urine is fervid, and penis is anorthosis often, has sexual impotence symptom, has had influence on love life, medical check then; yellowish fur, and pulse condition is heavy sliding, on inspection, is diagnosed as sexual impotence.
Take the present embodiment gained and there is the drug regimen tablet improving male sexual function, adopt twice daily, each 4-5 sheet, with warm water delivery service, 20 days courses for the treatment of.After taking a course for the treatment of, the malaise symptoms such as patient's self-induction is irritated, moist improve, and after taking two courses for the treatment of, sexual functional recovery is normal.
embodiment 4there is the drug regimen improving male sexual function, be prepared from (every part of 10g) primarily of following bulk drugs: Radix Angelicae Sinensis 17 parts, Fructus Lycii 18 parts, Semen Cuscutae 14 parts, Rhizoma Cimicifugae 15 parts, Herba Boschniakiae Rossicae 14 parts, Fructus Corni 16 parts, Caulis Spatholobi 18 parts, Radix Gentianae Macrophyllae 14 parts, Concha Ostreae 13 parts, Herba Epimedii 18 parts, Fructus Forsythiae 14 parts, Flos Nelumbinis pollen 18 parts, 15 parts, Cornu Cervi Pantotrichum, Herba Apocyni veneti 14 parts, Cortex Lycii 17 parts, Herba Eupatorii 16 parts.
The preparation method with the drug regimen granule improving male sexual function is:
(1) Semen Cuscutae yellow wine is boiled to snuff, take out, mash, add face and Mel and even, make cake, dry, pulverize, obtain medicated powder;
(2) get Cortex Lycii to clean, use rice water saturates, pull out, put into tank and obturage, then tank is put into pot and boil 4 hours, rear taking-up, dries;
(3) Cornu Cervi Pantotrichum is burned remove floss, scraping, be split into fragment, mix thoroughly with vinegar, put into pot and steam 25 minutes, take out, put into frying pan, fried dry, take out, be ground into fine powder together with pollen;
(4) Concha Ostreae is scrubbed clean, break into pieces, put into marmite, boil 40 minutes, Guan Huo, add Radix Angelicae Sinensis, Fructus Lycii, Rhizoma Cimicifugae, Herba Boschniakiae Rossicae, Fructus Corni, Caulis Spatholobi, Radix Gentianae Macrophyllae, Herba Epimedii, Fructus Forsythiae, Herba Eupatorii and step (2) made crude drug, soak 10 minutes, after being heated to boiling, turning little fire and decoct 30 minutes, Guan Huohou puts into Herba Apocyni veneti immediately, stirs, and adds a cover, place after 20 minutes, filter, collect filtrate, filtering residue is for subsequent use;
(5) by step (4) remaining filtering residue, add water and again decoct 30 minutes, filter, merge with step (4) made filtrate, stir evenly, lyophilization, pulverize, mix with step (1) (3) made medicated powder and fine powder, add pharmaceutical excipients, make soft material, cross 12 mesh sieve granulate, 60 DEG C of dryings, granulate, obtains granule.
Model case: xxx, man, 40 years old.Main suit: once had 4 years masturbation histories.Nearly 1 year position often adds night shift, occurs premature ejaculation symptom after promoting, after take Chinese medicine conditioning, after taking one month, self awareness for declining, anorthosis and morning vigorous, pain in the lumbar region, night sweat, after light exercise, obviously, medical check, is diagnosed as premature ejaculation in asthma.
Take the present embodiment gained and there is the drug regimen granule improving male sexual function, adopt twice daily, each one bag (4-6g), with warm boiled water, 20 days courses for the treatment of.After taking a course for the treatment of, patient body state takes a turn for the better, and without pain in the lumbar region, the malaise symptoms such as night sweat, after continuing to take two courses for the treatment of, patient fully recovers, and love life recovers normal, and patient's self-induction health is more full of strength comparatively before.
embodiment 5there is the drug regimen improving male sexual function, be prepared from (every part of 10g) primarily of following bulk drugs: Radix Angelicae Sinensis 15 parts, Fructus Lycii 15 parts, Semen Cuscutae 12.5 parts, Rhizoma Cimicifugae 14 parts, Herba Boschniakiae Rossicae 13 parts, Fructus Corni 15 parts, Caulis Spatholobi 16.5 parts, Radix Gentianae Macrophyllae 12.5 parts, Concha Ostreae 12.5 parts, Herba Epimedii 16 parts, Fructus Forsythiae 13 parts, Fructus Schisandrae Chinensis pollen 16.5 parts, 13 parts, Cornu Cervi Pantotrichum, Herba Apocyni veneti 12.5 parts, Cortex Lycii 15 parts, Herba Eupatorii 14 parts.
The preparation method with the drug regimen decoction improving male sexual function is:
(1) Semen Cuscutae yellow wine is boiled to snuff, take out, mash, add face and Mel and even, make cake, dry;
(2) get Cortex Lycii to clean, use rice water saturates, pull out, put into tank and obturage, then tank is put into pot and boil 4 hours, take out, dry;
(3) Cornu Cervi Pantotrichum is burned remove floss, scraping, be split into fragment, mix thoroughly with vinegar, put into pot and steam 25 minutes, take out, put into frying pan, fried dry, take out, be ground into fine powder;
(4) Concha Ostreae is scrubbed clean, break into pieces, put into marmite, boil 40 minutes, Guan Huo, add Radix Angelicae Sinensis, Fructus Lycii, Rhizoma Cimicifugae, Herba Boschniakiae Rossicae, Fructus Corni, Caulis Spatholobi, Radix Gentianae Macrophyllae, Herba Epimedii, Fructus Forsythiae, Herba Eupatorii and step (1) (2) made crude drug, soak 10 minutes, after being heated to boiling, turning little fire and decoct 30 minutes, Guan Huohou adds Herba Apocyni veneti immediately, stir, add a cover, place after 20 minutes, filter, collect filtrate;
(5) pollen is pulverized, join together with step (3) made fine powder in step (4) made filtrate, stir evenly, obtain decoction.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Radix Angelicae Sinensis: base is former: be the dry root of umbelliferae angelica.Nature and flavor: sweet, acrid, warm.Gui Jing: return liver, the heart, spleen channel.Function cures mainly: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.For amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.
Fructus Lycii: base is former: be the dry mature fruit of plant of Solanaceae lycium barbarum.Nature and flavor: sweet are flat.Gui Jing: return liver, kidney channel.Function cures mainly: nourishing the liver and kidney, replenishing vital essence to improve eyesight.For asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, and blurred vision is failed to understand.
Semen Cuscutae: be the dry mature seed of convolvulus cuscuta plant.Nature and flavor: sweet, temperature.Gui Jing: return liver,kidney,spleen warp.Function cures mainly: nourishing the liver and kidney, controlling nocturnal emission with astringent drugs reducing urination, antiabortive, improving eyesight, antidiarrheal.For impotence and seminal emission, dripping urination, enuresis frequent micturition, soreness of the waist and knees, blurred vision tinnitus, vaginal bleeding due to deficiency of the kidney during pregnancy, frequent fetal movement, spleen is suffered from a deficiency of the kidney and is rushed down; Externally treating leucoderma.
Rhizoma Cimicifugae: base is former; For the dry rhizome of ranunculaceae plant C.heracleifolia, Cimicifuga Dahurica or Rhizoma Cimicifugae.Nature and flavor: pungent, micro-sweet, are slightly cold.Gui Jing: return lung, spleen, stomach, large intestine channel.Function cures mainly: deliver rash, heat-clearing and toxic substances removing, elevate a turnable ladder yang-energy.For headache due to pathogenic wind-heat, toothache, aphtha, laryngopharynx swelling and pain, measles without adequate eruption, YANG toxin syndrome sends out speckle; Proctoptosis, uterine prolapse.
Herba Boschniakiae Rossicae: base is former: be the herb of Orobanchaceae plant plait Herba Cistanches.Chemical analysis: aerial parts is containing boschniakine and Herba Boschniakiae Rossicae lactone.Again containing C9, C10 and C11 terpene lactones.Rhizome is containing mannitol, alkaloid.Nature and flavor: sweet in the mouth, salty, warm in nature.Function cures mainly: kidney invigorating and YANG supporting, intestine moistening, hemostasis.Control impotence due to deficiency of the kidney, chills and pain of the waist and kness, senility habitual constipation, cystitis.
Fructus Corni: base is former: be the drying and ripening sarcocarp of Cornaceae plant Fructus Corni.Nature and flavor: sour, puckery, tepor.Gui Jing: return liver, kidney channel.Function cures mainly: liver and kidney tonifying, essence astringing and desertion stemming.For vertigo and tinnitus, soreness of waist and knee joint, impotence and seminal emission, enuresis frequent micturition, bleeding not during menses, profuse sweating is collapsed.Interior-heat is quenched one's thirst.
Caulis Spatholobi: base is former: be the dry rattan of leguminous plant spatholobus suberectus (Caulis Sargentodoxae, Radix seu Caulis Verntilaginis Leiocarpae, SANYE Caulis Spatholobi, nine layers of wind).Nature and flavor: bitter, sweet, temperature.Gui Jing: return liver, kidney channel.Function cures mainly: enrich blood, and invigorates blood circulation, dredging collateral.For menoxenia, blood deficiency and yellow complexion, paralysis and numbness, rheumatic arthralgia.
Radix Gentianae Macrophyllae: base is former: be the dry root of gentianaceae plant Radix Gentianae Macrophyllae, gentiana straminea maxim, gentiana crassicaulis Duthie or Gentiana dahurica.Nature and flavor: pungent, bitter are flat.Gui Jing: return stomach, liver, gallbladder meridian.Function cures mainly: wind-damp dispelling, clearing away damp-heat, stopping numbness pain.For rheumatic arthralgia, the contracture of muscle arteries and veins, joint is ached, afternoon fever, and infantile malnutrition generates heat.
Concha Ostreae: base is former: be the shell of the long Concha Ostreae of Ostreidae animal, Dalian Bay Concha Ostreae or Crassostrea rivularis.Nature and flavor: salty, are slightly cold.Gui Jing: return liver, gallbladder, kidney channel.Function cures mainly: tranquillization with heavy prescription, YANG hyperactivity suppressing nourishing YIN, hard masses softening and resolving.For insomnia of palpitating with fear, vertigo and tinnitus, scrofula sucutaneous nodule, lump in the abdomen mass in the abdomen.Concha Ostreae (calcined) convergence is astringent or styptic treatment for spontaneous sweating.For spontaneous sweating, seminal emission metrorrhagia and leukorrhagia, stomachache acid regurgitation.
Herba Epimedii: base is former: be the stem and leaf of Berberidaceae plant Herba Epimedii, Epimedium brevicornum or Epimedium sagittatum.Nature and flavor: acrid, sweet, warm.Gui Jing: return liver, kidney channel.Function cures mainly: kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.For impotence and seminal emission, muscles and bones flaccidity is soft, rheumatic arthralgia, numbness contracture; Climacteric hypertension.
Fructus Forsythiae: base is former: be the dry fruit of Oleaceae plants Fructus Forsythiae.Nature and flavor: bitter, are slightly cold.Gui Jing: return lung, the heart, small intestine meridian.Function cures mainly: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.For carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease from the beginning of, warmly join the army, high hot excessive thirst, coma sends out speckle, pyretic stranguria urine retention.
Pollen (Pollen Codonopsis or Fructus Schisandrae Chinensis pollen or Pollen Brassicae campestris or Flos Nelumbinis pollen, preferred Fructus Schisandrae Chinensis pollen): pollen is the male sex cell of plant, effect: 1 strengthens human body comprehensive immunologic function; 2 is anti-aging, beauty treatment; 3 control brain cardiovascular diseases; 4 nervous system regulation, hypnotic; 5 control prostatosis; 6 fat-reducing; 7 regulate gastrointestinal function; 8 hepatoprotective; The multi-efficiencies such as 9 auxiliary treatment other diseases.Pollen Codonopsis: sweet in the mouth, put down, return spleen, lung meridian.Function cures mainly: invigorating the spleen and replenishing QI, spleen invigorating of invigorating blood circulation, replenishing QI and blood.Wherein containing Saponin, the alkaloid of biological polyoses and trace, has excitation to nervous system.Energy enhancing body resistance, auxiliary treatment neurasthenia, insomnia, inappetence, myasthenia of limbs, cardiopalmus, breathes hard, xerostomia, spontaneous perspiration, proctoptosis, uterine prolapse.Fructus Schisandrae Chinensis pollen: composition: 18 seed amino acid total contents reach 21%, tannin (gallotannic acid) content reaches 0.52%.Effect: restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming, the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity, nourishing the lung to arrest cough.Be adapted to especially lumbago due to renal deficiency, emission and spermatorrhea, excessive, the busy male of tobacco and wine eat.Pollen Brassicae campestris: composition: the flavonol higher containing content and first anthocyanidin, function cures mainly: protecting liver and expelling toxin, Sweeling-eliminating medicine powder pain, has atherosclerosis, treatment varicose ulcer, prostatitis, reduction cholesterol and radiation-resistant effect.Long-term taking Pollen Brassicae campestris, can prevention and therapy prostatosis, and significantly improving sexual function, is the jinx of male prostatitis.Flos Nelumbinis pollen: major function shows as: 1, skin-protecting face nursing, adjustment constipation, endocrine regulation, tonify Qi of the kidney, the removing heat from blood that clears away heart-fire, relieving heat toxin, disappear wet to dispel the wind, endocrine regulation, can dispelling speckles and whitening face, inrigorating qi and promoting blood circulation, moistening dryness for relaxing bowels.2, skin-care functional is distinguished.Good to the therapeutic effect of the diseases such as freckle, comedo, insomnia, the intestines and stomach.
Cornu Cervi Pantotrichum: base is former: be the not yet ossified young horn of animal in deer family Cervus nippon Temminck or Cervus elaphus linnaeus.Nature and flavor: sweet, salty, temperature.Gui Jing: return kidney, Liver Channel.Function cures mainly: invigorating kidney-YANG, benefiting essence-blood, bone and muscle strengthening, adjusts punching to appoint, holder sore.For sexual impotence spermatorrhea, cold womb is infertile, weakness and emaciation, Mental fatigue, fear of cold, and vertigo and tinnitus is deaf, and spinal column cold type of pain, muscles and bones flaccidity is soft, bleeding not during menses, and carbuncle of yin nature is not held back.
Herba Apocyni veneti: base is former: be the herb of apocynaceae plant Herba Apocyni veneti.Nature and flavor: sweet, bitter, cold.Function cures mainly: relieve inflammation or internal heat, blood pressure lowering, heart tonifying, diuresis.Control heart disease, hypertension, neurasthenia, hepatitis abdominal distention, nephritis edema.
Cortex Lycii: base is former: be the dry root bark of matrimony vine of solanaceae plant or lycium barbarum.Nature and flavor: sweet, cold.Gui Jing: return lung, liver, kidney channel.Function cures mainly: removing heat from blood removes and steams, lung heat clearing pathogenic fire reducing.For deficiency of YIN hectic fever, hectic fever due to YIN-deficiency night sweat, cough due to lung-heat, spitting of blood, epistaxis, interior-heat is quenched one's thirst.
Herba Eupatorii: base is former: be the dry aerial parts of feverfew Herba Eupatorii.Nature and flavor: pungent are flat.Gui Jing: return spleen, stomach, lung meridian.Function cures mainly: removing dampness by means of aromatics, and appetizing of being amusing, delivers expelling summer-heat.For turbid damp obstructing in middle-JIAO, gastral cavity painful abdominal mass vomiting and nausea, sweet greasy in mouth, halitosis, sialism, heat-damp in summer table disease, feeling of fullness in the head is uncomfortable in chest.
test example 1gained of the present invention has the test of pesticide effectiveness of the drug regimen (embodiment 5) improving male sexual function: subjects: male rat (body weight 70-90 gram) and male mice (body weight 13-15 gram and 30-35 gram).
(1) on the impact of immature male Mouse Weight, Prostato-Seminal vesicle, levator ani-sponge ball flesh and preputial glands weight
Method: 80 immature male mices are divided into 4 groups, often organizes 20, and Four composition Wei matched group, Methyl testosterone group, low dose group of the present invention and high dose group.To often organizing mice, every day distinguishes gavage once, matched group clear water (10ml/kg) gavage, low dose group and high dose group use the dosage gavage of 0.5g/kg and 1.2g/kg respectively, the Methyl testosterone group Methyl testosterone gavage of 5mg/kg dosage, the not continuous gavage of Four composition 15 days, after last gavage 24 hours, by each group of mouse weights, draw neck to put to death, then extract testis, Prostato-Seminal vesicle, levator ani-sponge ball flesh and preputial glands and weigh.Result of the test is in table 1.
Table 1 pair immature male Mouse Weight, testis, Prostato-Seminal vesicle, levator ani-sponge ball flesh and
The impact of preputial glands weight ( ± SE)
Note: compared with matched group, * P < 0.05, * * P < 0.01, * * * P < 0.005.
As shown in Table 1, compared with matched group male mice, the weight of the body weight of the mice of low dose group of the present invention, high dose group and Methyl testosterone group, testis, levator ani-sponge ball flesh, Prostato-Seminal vesicle and preputial glands is all larger, illustrate that product of the present invention and Methyl testosterone can promote the growth of the sexual organ of male mice, also illustrate that product of the present invention has the effect of similar androgen.
(2) on the impact of bull castration Prostato-Seminal vesicle, levator ani-sponge ball flesh and preputial glands weight
Method: pretreatment before test, by mice etherization, cuts skin of scrotum, takes out testis and together excises together with epididymis, then by skin closure, after five weeks, after the abundant atrophy of its gonophore, test.Castration mouse is divided into 4 groups, often organizes 20, Four composition Wei matched group, Methyl testosterone group, low dose group of the present invention and high dose group.To often organizing mice, every day distinguishes gavage once, matched group clear water (10ml/kg) gavage, low dose group of the present invention and high dose group use the dosage gavage of 0.5g/kg and 1.2g/kg respectively, the Methyl testosterone group Methyl testosterone gavage of 5mg/kg dosage, each group of mice, although continuous gavage 15 days, after last gavage 24 hours, draws neck to put to death by Four composition.Prostate glands-Seminal vesicle, levator ani-sponge ball flesh and preputial glands are weighed.Result of the test is in table 2.
Table 2 pair bull castration mouse Prostato-Seminal vesicle, levator ani-sponge ball and
The impact of preputial glands weight ( ± SE/ unit: mg)
Note: compared with matched group, * P < 0.05, * * P < 0.01, * * * P < 0.005.
As shown in Table 2, good all compared with matched group of the Prostato-Seminal vesicle of Methyl testosterone group and product group of the present invention, levator ani-sponge ball and preputial glands weight, illustrate that Methyl testosterone and product of the present invention can promote the growth of bull castration mouse sexual organ, reduce castration to the impact of male mice sexual organ.Product of the present invention has the effect of androgen sample to bull castration mouse, and the effect of high dose group is comparatively obvious, and effect is better than Methyl testosterone.
(3) to the toxicity of mice
1. acute toxicity: press 10g/kg gavage products made thereby of the present invention to 15 mices, observes 48 hours, and mice outward appearance and behavior, all without change, also occur without dead.
2. subacute toxicity: male rat is divided two groups, often organize 10, experimental group gavages product 10g/kg of the present invention, matched group gavages isopyknic normal saline, gavages 30 days continuously, gavages latter 24 hours for the last time, to weigh rat body weight, put to death rat, get blood, liver, kidney check, and core, liver, spleen, stomach, kidney and testis tissue carry out microscopy as pathological section.
Result shows, and the form of the heart of rat, liver, spleen, stomach, kidney and testis tissue is all unchanged, and routine blood test, liver function and renal function are also all normal, and the product of the present invention of long-term taking 10g/kg dosage is described, very low to the toxicity of rat.
Chinese angelica blood supplementing in formula of the present invention is invigorated blood circulation, Fructus Lycii nourishing the liver and kidney, Semen Cuscutae controlling nocturnal emission with astringent drugs reducing urination, Rhizoma Cimicifugae elevate a turnable ladder yang-energy, Herba Boschniakiae Rossicae kidney invigorating and YANG supporting, Fructus Corni liver and kidney tonifying, Caulis Spatholobi promoting blood circulation to remove obstruction in the collateral, Radix Gentianae Macrophyllae clearing away damp-heat, the nourishing YIN of Concha Ostreae YANG hyperactivity suppressing, Herba Epimedii kidney-replenishing, Fructus Forsythiae heat-clearing and toxic substances removing, Cornu Cervi Pantotrichum invigorating kidney-YANG, the blood pressure lowering of Herba Apocyni veneti heart tonifying, Cortex Lycii lung heat clearing pathogenic fire reducing, Herba Eupatorii removing dampness by means of aromatics, multiple medicines share, collaborative performance effect, regulate function of human body, improve sexual function, and safety is without obvious toxic-side effects.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.

Claims (10)

1. there is the drug regimen improving male sexual function, it is characterized in that, be prepared from primarily of following bulk drugs, be weight portion: Radix Angelicae Sinensis 12-18, Fructus Lycii 9-21, Semen Cuscutae 10-15, Rhizoma Cimicifugae 12-16, Herba Boschniakiae Rossicae 11-15, Fructus Corni 13-17, Caulis Spatholobi 14-19, Radix Gentianae Macrophyllae 10-15, Concha Ostreae 11-14, Herba Epimedii 12-20, Fructus Forsythiae 10-16, pollen 14-19, Cornu Cervi Pantotrichum 9-17, Herba Apocyni veneti 9-16, Cortex Lycii 11-19, Herba Eupatorii 10-18.
2. there is drug regimen as claimed in claim 1 that improve male sexual function, it is characterized in that, Radix Angelicae Sinensis 13-17, Fructus Lycii 12-18, Semen Cuscutae 11-14, Rhizoma Cimicifugae 13-15, Herba Boschniakiae Rossicae 12-14, Fructus Corni 14-16, Caulis Spatholobi 15-18, Radix Gentianae Macrophyllae 11-14, Concha Ostreae 12-13, Herba Epimedii 14-18, Fructus Forsythiae 12-14, pollen 15-18, Cornu Cervi Pantotrichum 11-15, Herba Apocyni veneti 11-14, Cortex Lycii 13-17, Herba Eupatorii 12-16 is (preferred, Radix Angelicae Sinensis 15, Fructus Lycii 15, Semen Cuscutae 12.5, Rhizoma Cimicifugae 14, Herba Boschniakiae Rossicae 13, Fructus Corni 15, Caulis Spatholobi 16.5, Radix Gentianae Macrophyllae 12.5, Concha Ostreae 12.5, Herba Epimedii 16, Fructus Forsythiae 13, pollen 16.5, Cornu Cervi Pantotrichum 13, Herba Apocyni veneti 12.5, Cortex Lycii 15, Herba Eupatorii 14).
3. have the drug regimen improving male sexual function as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable decoction, its preparation method is:
(1) Semen Cuscutae yellow wine is boiled to snuff, take out, mash, add face and Mel and even, make cake, dry;
(2) get Cortex Lycii to clean, use rice water saturates, pull out, put into tank and obturage, then tank is put into pot and boil 3-5 hour (preferred, put into pot and boil 4 hours), take out, dry;
(3) Cornu Cervi Pantotrichum is burned remove floss, scraping, be split into fragment, mix thoroughly with vinegar, put into pot and steam 20-30 minute (preferred, to put into pot and steam 25 minutes), take out, put into frying pan, fried dry, take out, be ground into fine powder;
(4) Concha Ostreae is scrubbed clean, break into pieces, put into marmite, boil 40 minutes, Guan Huo, add Radix Angelicae Sinensis, Fructus Lycii, Rhizoma Cimicifugae, Herba Boschniakiae Rossicae, Fructus Corni, Caulis Spatholobi, Radix Gentianae Macrophyllae, Herba Epimedii, Fructus Forsythiae, Herba Eupatorii and step (1) (2) made crude drug, soak 10 minutes, after being heated to boiling, turning little fire and decoct, Guan Huohou adds Herba Apocyni veneti immediately, stir, add a cover, place after 20 minutes, filter, collect filtrate;
(5) pollen is pulverized, join together with step (3) made fine powder in step (4) made filtrate, stir evenly, obtain decoction.
4. have the preparation method of the drug regimen decoction improving male sexual function as claimed in claim 3, it is characterized in that, step (4) turn little fire decocts 20-40 minute, and (preferred, 25-35 minute decocted by a turn little fire; Be more preferably, turn little fire and decoct 30 minutes).
5. have the drug regimen improving male sexual function as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable pill, its preparation method is:
(1) Semen Cuscutae yellow wine is boiled to snuff, take out, mash, add face and Mel and even, make cake, dry;
(2) get Cortex Lycii to clean, use rice water saturates, pull out, put into tank and obturage, then tank is put into pot and boil 3-5 hour (preferred, put into pot and boil 4 hours), take out, dry;
(3) Cornu Cervi Pantotrichum is burned remove floss, scraping, be split into fragment, mix thoroughly with vinegar, put into pot and steam 20-30 minute (preferred, to put into pot and steam 25 minutes), take out, put into frying pan, fried dry, take out, be ground into fine powder;
(4) by Radix Angelicae Sinensis, Rhizoma Cimicifugae, Fructus Corni, Radix Gentianae Macrophyllae, Concha Ostreae, Herba Epimedii and Fructus Forsythiae decontamination, slightly soak, put into the micro-stir-fry of pot, taking-up is dried in the air cool, pulverizes and sieves, obtain medicated powder with pollen, Fructus Lycii together with step (1) (2) made crude drug;
(5) Herba Boschniakiae Rossicae, Caulis Spatholobi, Herba Apocyni veneti and Herba Eupatorii are picked clean impurity, put into marmite and boil 20 minutes, filter, collect filtrate, heating is concentrated, mixes, and add pharmaceutical excipients with step (3) (4) made fine powder and medicated powder, generally makes ball, obtains pill.
6. have the preparation method of the drug regimen pill improving male sexual function as claimed in claim 5, it is characterized in that, step (4) was pulverized 100-160 mesh sieve and (preferably, was pulverized 120-140 mesh sieve; Be more preferably, pulverized 130 mesh sieves).
7. have the drug regimen improving male sexual function as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable tablet, its preparation method is:
(1) Semen Cuscutae yellow wine is boiled to snuff, take out, mash, add face and Mel and even, make cake, dry;
(2) get Cortex Lycii to clean, use rice water saturates, pull out, put into tank and obturage, then tank is put into pot and boil 3-5 hour (preferred, put into pot and boil 4 hours), take out, dry;
(3) Cornu Cervi Pantotrichum is burned remove floss, scraping, be split into fragment, mix thoroughly with vinegar, put into pot and steam 20-30 minute (preferred, to put into pot and steam 25 minutes), take out, put into frying pan, fried dry, take out, be ground into fine powder;
(4) by Radix Angelicae Sinensis, Fructus Lycii, Rhizoma Cimicifugae, Fructus Corni, Radix Gentianae Macrophyllae, Concha Ostreae, Herba Epimedii, Fructus Forsythiae and pollen decontamination, slightly soak, put into the micro-stir-fry of pot, taking-up is dried in the air cool, the 100-160 mesh sieve that pulverizes and sieves together with step (1) (2) made crude drug (preferably, pulverized 120-140 mesh sieve; Be more preferably, pulverized 130 mesh sieves), obtain medicated powder;
(5) Herba Boschniakiae Rossicae, Caulis Spatholobi, Herba Apocyni veneti and Herba Eupatorii are picked clean impurity, put into marmite and boil 20 minutes, filter, collect filtrate, heating is concentrated, mix with (4) made medicated powder, lyophilization, pulverizes, then mixes with step (3) made fine powder, obtained mixed powder, is finally pressed into circular or other forms of tablet dosage form according to the preparation for processing of tablet.
8. there is the preparation method of the drug regimen tablet improving male sexual function as claimed in claim 7, it is characterized in that, in step (5) made tablet, the amount of mixed powder contained by every sheet is that 0.2-0.3g(is preferred, and contained by every sheet, the amount of mixed powder is 0.25g).
9. have the drug regimen improving male sexual function as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable granule, its preparation method is:
(1) Semen Cuscutae yellow wine is boiled to snuff, take out, mash, add face and Mel and even, make cake, dry, pulverize, obtain medicated powder;
(2) get Cortex Lycii to clean, use rice water saturates, pull out, put into tank and obturage, then tank is put into pot boil, rear taking-up, dries;
(3) Cornu Cervi Pantotrichum is burned remove floss, scraping, be split into fragment, mix thoroughly with vinegar, put into pot and steam 20-30 minute (preferred, to put into pot and steam 25 minutes), take out, put into frying pan, fried dry, take out, be ground into fine powder together with pollen;
(4) Concha Ostreae is scrubbed clean, break into pieces, put into marmite, boil 40 minutes, Guan Huo, add Radix Angelicae Sinensis, Fructus Lycii, Rhizoma Cimicifugae, Herba Boschniakiae Rossicae, Fructus Corni, Caulis Spatholobi, Radix Gentianae Macrophyllae, Herba Epimedii, Fructus Forsythiae, Herba Eupatorii and step (2) made crude drug, soak 10 minutes, after being heated to boiling, a turn little fire decocts 20-40 minute, and (preferred, 25-35 minute decocted by a turn little fire; Be more preferably, turn little fire and decoct 30 minutes), Guan Huohou puts into Herba Apocyni veneti immediately, stirs, and adds a cover, and places after 20 minutes, filters, and collect filtrate, filtering residue is for subsequent use;
(5) by step (4) remaining filtering residue, add water and again decoct 30 minutes, filter, merge with step (4) made filtrate, stir evenly, lyophilization, pulverize, mix with step (1) (3) made medicated powder and fine powder, add pharmaceutical excipients, make soft material, cross 12 mesh sieve granulate, 60 DEG C of dryings, granulate, obtains granule.
10. have the preparation method of the drug regimen granule improving male sexual function as claimed in claim 9, it is characterized in that, step (2) is put into pot and is boiled 3-5 hour (preferred, to put into pot and boil 4 hours).
CN201510075604.7A 2015-02-13 2015-02-13 Medicine composition with effect of improving male sexual functions and preparation method thereof Pending CN104606370A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101062193A (en) * 2007-05-18 2007-10-31 孟灵源 Health-care wine for invigorating kidney and strengthening body

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101062193A (en) * 2007-05-18 2007-10-31 孟灵源 Health-care wine for invigorating kidney and strengthening body

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
吴大真等: "《现代名中医前列腺治疗绝技》", 30 September 2004, 科学技术文献出版社 *

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