CN1943778A - The mixture of cobra venom and Chinese medical herb extract and its application - Google Patents

Abstract

This invention discloses a mixture of cobra venom with Chinese herb extracts and its applications. , of which the weight portion is 0.004-0.006 and 3-6 respectively. The said Chinese herb extracts are prepared according to the following weight ratios: Succinum (13~17),Caulis Sargentodoxae (8~12),Rhizoma Curculiginis (8~12),Rhizoma erubescens Schott (6~10),Scolopendra (2~6),Dysosma versipellis (6~10 ),Gekko (8~12),Radix Cynanchi Paniculati (6~10),scorpion (8~12),Rhizoma Zingiberis Recens (8~12),Radix Notoginseng (8~12),Herba Lobellae Chinensis (15~25),Ganoderma lucidum (15~25),Cordyceps sinensis (3~7),Radix Glycyrrhizae (25~35),Paris polyphylla (8~12).The mixture of Cobra Venom with Chinese herb extracts in this invention has a remarkable curative effect on cancer. It is able to satisfy people's requirements and worth promoting its application.

Description

The mixture of cobra venom and Chinese herbal medicine extract and application

Technical field

The present invention relates to the mixture and the application of cobra venom and Chinese herbal medicine extract, be specifically related to the application in preparation treatment cancer drug.

Background technology

Cancer, promptly malignant tumor is the important diseases of current harm humans life, existing Therapeutic Method comprises: (1) operative treatment; Need carry out in early days, what have can not perform the operation, and cannot say for sure to effect a radical cure; (2) chemotherapy and radiotherapy: the course of treatment is long, and toxicity is arranged, and has to end, also difficult radical cure; (3) interventional therapy, gamma knife treatment comprise laser and ultrasonic therapeutic: topical application can not be treated the general tumor, though toxicity reduces but still can not eliminate fully, also difficult radical cure; (4) stem cell transplantation: pairing is difficult, and expense is expensive, is limited to the part patient, also dangerous property; (5) Chinese medicine: it is perfect to require study.Employed in the world at present Venine product all be single extract, can't kill cancer cell, have only compatiblely with relevant Chinese medicine, just make the active protease prolonged survival period, reach kill cancer cell.

Therefore, provide a kind of medicine of therapeutic tumor of new safety be people very expectation.

Summary of the invention

The technical issues that need to address of the present invention are mixture and the application thereof that disclose a kind of cobra venom and Chinese herbal medicine extract, to overcome the deficiencies in the prior art, satisfy people's needs.

Technical conceive of the present invention is such:

Cancerous cell is generally survived between the blood and passages through which vital energy circulates of human body, it mainly draws the marrow of human body for supporting, when cancer occurs, the immunity straight line of human body descends, no longer to offer the five internal organs, six internal organs, also has each cell, passages through which vital energy circulates, the marrow of blood, human survival mainly just can prolong life with their continuous existence.

Cobra venom is an admixture poison, but it is mainly based on neural poison, has a material that the effect of kill cancer cell is arranged in the snake venom, when it with after relevant Chinese medicine is compatible, the organized enzyme in the snake venom does not have destroyed, on the contrary, its character has played variation.

Plurality of Chinese among the cobra venom organized enzyme can make the immunity of each big organ pipe of human body be improved, the character of the snake venom in the organized enzyme can not injure human body with metering, the opposite organized enzyme that it has directly removes to seek cancerous cell after entering the passages through which vital energy circulates of human body, kill cancer cell, the neural factor that is hurt is repaired and regeneration, thereby accelerated the rehabilitation of human body.

With a Dan Xi, " be not pursuit of advanced studiesization to precise and tiny people, be to create the medicament that this is startled the universe and moved the gods "!

Because this medicament, she has life, can bring glad tidings to the cancer patient well.

The component of the mixture of cobra venom of the present invention and Chinese herbal medicine extract and parts by weight are:

0.004～0.006 part of cobra venom

3～6 parts of Chinese herbal medicine extracts.

Preferably:

0.005 part of cobra venom

4 parts of Chinese herbal medicine extracts.

The weight portion of above-mentioned Chinese herbal medicine extract is to be benchmark with herbal raw material before extracting;

Said Chinese herbal medicine extract is the feedstock production that adopts following part by weight:

13～17 parts of succinums, 8～12 parts of Caulis Sargentodoxaes, 8～12 parts of Rhizoma Curculiginis, 6～10 parts of Rhizoma Arisaematiss, 2～6 parts of Scolopendras, 6～10 parts of Radix et Rhizoma Dysosmatiss, 8～12 parts of Gekko Swinhonis, 6～10 parts of Radix Cynanchi Paniculatis, 8～12 parts of Scorpios, 8～12 parts in Rhizoma Zingiberis Recens, 8～12 parts in Radix Notoginseng, 15～25 parts of Herba Lobeliae Chinensis, 15～25 parts of Ganodermas, 3～7 parts of Cordyceps, 25～35 parts in Radix Glycyrrhizae, 8～12 parts of Rhizoma Paridis.

Preferably:

15 parts of succinums, 10 parts of Caulis Sargentodoxaes, 10 parts of Rhizoma Curculiginis, 8 parts of Rhizoma Arisaematiss, 4 parts of Scolopendras, 8 parts of Radix et Rhizoma Dysosmatiss, 10 parts of Gekko Swinhonis, 8 parts of Radix Cynanchi Paniculatis, 10 parts of Scorpios, 10 parts in Rhizoma Zingiberis Recens, 10 parts in Radix Notoginseng, 20 parts of Herba Lobeliae Chinensis, 20 parts of Ganodermas, 5 parts of Cordyceps, 30 parts in Radix Glycyrrhizae, 10 parts of Rhizoma Paridis.

The preparation method of said Chinese herbal medicine extract is as follows:

Above-mentioned Chinese herbal medicine is pulverized, be soaked in water or volumetric concentration and be 35～95% ethanol water 2～10 hours, water or volumetric concentration are that the weight consumption of 35～95% ethanol water is 300～400 times of Chinese herbal medicine, filter, and collect filtrate;

Proportionally, the filtrate of collecting is mixed with cobra venom, promptly obtain the mixture of said cobra venom and Chinese herbal medicine extract.

The invention still further relates to a kind of compositions, it is characterized in that, contain the said mixture for the treatment of effective dose and pharmaceutically acceptable carrier, said carrier comprises diluent, and as water, sweeting agent such as sucrose etc. are so that different crowds takes.

The mixture of said cobra venom of the present invention and Chinese herbal medicine extract has significant curative effect for cancer as middle and advanced stage leukemia, the brain cancer, esophageal carcinoma, gastric cancer, pulmonary carcinoma, pouring scar cancer, osteocarcinoma, renal carcinoma etc.

Adopt mixture of the present invention, to 100 routine cancer patients (comprising child or adult) treatment, the result is as follows:

At 2006 on date	8-12 year	12-30 year	30-45 year	45-80 year
					June	Effective 94%	Effective 95%	Effective 93%	Effective 94%
July	Effective 93%	Effective 94%	Effective 94%	Effective 93%
					August	Effective 95%	Effective 93%	Effective 95%	Effective 92%

Wherein:

35 examples are pulmonary carcinoma, and 30 examples are osteocarcinoma, and 35 examples are lymphatic cancer.

Can be by oral method, above-mentioned mixture is put on the patient who needs treatment, general dosage is 0.1～0.3mg/ kg body weight, specifically can be according to patient's the state of an illness, age etc., by doctor's decision, be preferably in the usefulness that is taken at bed time after the dinner.The toxicity test result is as follows:

Group	Dosage	Toxic reaction
			Cobra venom	0.35mg 0.04mg	The dead immediately white mice survival of white mice
The present invention	0.40mg 0.01mg	The survival of mice dying white mice

By above-mentioned disclosed technical scheme as seen, the mixture of agkistrodon acutus venom of the present invention and Chinese herbal medicine extract all has very significant curative effect to various ages and cancer, can satisfy people's needs, is worthy of popularization.

The specific embodiment

Embodiment 1

Cobra venom 0.005 gram, herbal raw material 4 grams.

In the herbal raw material:

15 parts of succinums, 10 parts of Caulis Sargentodoxaes, 10 parts of Rhizoma Curculiginis, 8 parts of Rhizoma Arisaematiss, 4 parts of Scolopendras, 8 parts of Radix et Rhizoma Dysosmatiss, 10 parts of Gekko Swinhonis, 8 parts of Radix Cynanchi Paniculatis, 10 parts of Scorpios, 10 parts in Rhizoma Zingiberis Recens, 10 parts in Radix Notoginseng, 20 parts of Herba Lobeliae Chinensis, 20 parts of Ganodermas, 5 parts of Cordyceps, 30 parts in Radix Glycyrrhizae, 10 parts of Rhizoma Paridis.

The preparation method of said Chinese herbal medicine extract is as follows:

Above-mentioned Chinese herbal medicine is pulverized, be soaked in the water, 10 hours, filter, collect filtrate, the weight consumption of water is 300 times of Chinese herbal medicine, proportionally, the filtrate of collecting is mixed with agkistrodon acutus venom, promptly obtains the mixture of said agkistrodon acutus venom and Chinese herbal medicine extract.

Embodiment 2

Cobra venom 0.005 gram, herbal raw material 6 grams.Other are with embodiment 1.

In the herbal raw material:

13 parts of succinums, 12 parts of Caulis Sargentodoxaes, 8 parts of Rhizoma Curculiginis, 6 parts of Rhizoma Arisaematiss, 6 parts of Scolopendras, 6 parts of Radix et Rhizoma Dysosmatiss, 12 parts of Gekko Swinhonis, 10 parts of Radix Cynanchi Paniculatis, 8 parts of Scorpios, 8 parts in Rhizoma Zingiberis Recens, 12 parts in Radix Notoginseng, 25 parts of Herba Lobeliae Chinensis, 25 parts of Ganodermas, 3 parts of Cordyceps, 35 parts in Radix Glycyrrhizae, 12 parts of Rhizoma Paridis.

Embodiment 3

The product of embodiment 1 or 2 is added sweeting agent sucrose, and part by weight is:

1 part in the mixture of cobra venom and Chinese herbal medicine extract, 0.5 part of sucrose obtains to contain pleasantly sweet oral liquid.

Claims (6)

1. the mixture of cobra venom and Chinese herbal medicine extract is characterized in that component and parts by weight are:

0.004～0.006 part of cobra venom

3～6 parts of Chinese herbal medicine extracts

The weight portion of above-mentioned Chinese herbal medicine extract is to be benchmark with herbal raw material before extracting;

Said Chinese herbal medicine extract is the feedstock production that adopts following part by weight:

13～17 parts of succinums, 8～12 parts of Caulis Sargentodoxaes, 8～12 parts of Rhizoma Curculiginis, 6～10 parts of Rhizoma Arisaematiss, 2～6 parts of Scolopendras, 6～10 parts of Radix et Rhizoma Dysosmatiss, 8～12 parts of Gekko Swinhonis, 6～10 parts of Radix Cynanchi Paniculatis, 8～12 parts of Scorpios, 8～12 parts in Rhizoma Zingiberis Recens, 8～12 parts in Radix Notoginseng, 15～25 parts of Herba Lobeliae Chinensis, 15～25 parts of Ganodermas, 3～7 parts of Cordyceps, 25～35 parts in Radix Glycyrrhizae, 8～12 parts of Rhizoma Paridis.

2. the mixture of agkistrodon acutus venom according to claim 1 and Chinese herbal medicine extract is characterized in that: 0.005 part of cobra venom, 4 parts of Chinese herbal medicine extracts.

3. a compositions is characterized in that, contains claim 1 or the 2 said mixture and the pharmaceutically acceptable carrier for the treatment of effective dose.

4. claim 1 or the 2 said mixture application in preparation treatment cancer drug.

5. according to the said application of claim 4, it is characterized in that said cancer comprises middle and advanced stage leukemia, the brain cancer, esophageal carcinoma, gastric cancer, pulmonary carcinoma, pouring scar cancer, osteocarcinoma or renal carcinoma.

6. prepare the method for the mixture of claim 1 or 2 described cobra venoms and Chinese herbal medicine extract, it is characterized in that the preparation method of said Chinese herbal medicine extract is as follows:

Above-mentioned Chinese herbal medicine is pulverized, be soaked in water or volumetric concentration and be 35～95% ethanol water 2～10 hours, water or volumetric concentration are that the weight consumption of 35～95% ethanol water is 300～400 times of Chinese herbal medicine, filter, and collect filtrate;

Proportionally, the filtrate of collecting is mixed with cobra venom, promptly obtain the mixture of said cobra venom and Chinese herbal medicine extract.