CN105168781A - Traditional Chinese medicine composite for treating brain cancer and preparation method thereof - Google Patents

Traditional Chinese medicine composite for treating brain cancer and preparation method thereof Download PDF

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CN105168781A
CN105168781A CN201510625214.2A CN201510625214A CN105168781A CN 105168781 A CN105168781 A CN 105168781A CN 201510625214 A CN201510625214 A CN 201510625214A CN 105168781 A CN105168781 A CN 105168781A
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herba
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crude drug
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brain cancer
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不公告发明人
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Abstract

The invention discloses a traditional Chinese medicine composite for treating brain cancer and a preparation method thereof. The traditional Chinese medicine composite is mainly prepared from, by weight, 9-15 parts of common selfheal fruit-spike, 10-14 parts of phoen hawksbear root, 6-9 parts of typhae pollen (wrapped during decoction), 10-13 parts of small-flowered beggar's-ticks, 8-14 parts of dysosma versipelis, 7-12 parts of ilex pernyi franch, 9-14 parts of scrophulariae, 7-13 parts of acid ginger, 6-10 parts of white muscardine silkworm, 8-13 parts of kerr treebine root, 10-15 parts of chorophytum comosum, 8-16 parts of franchet's pea tree flower, 9-13 parts of herba ecliptae, 11-16 parts of herba rabdosiae, 7-14 parts of little groundcherry herb or fruit and 9-12 parts of pellionia repens. The traditional Chinese medicine composite can remarkably relieve and even eradicate brain cancer symptoms, and is safe, free of side effects, convenient to take, low in price, capable of preventing operative complications and sequelae, free of tolerance, effective in treatment and not prone to relapse.

Description

A kind of Chinese medicine composition and method for making curing the brain cancer
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of Chinese medicine composition and the method for making of curing the brain cancer.
Background technology
The brain cancer refers to that growth is in the neoplasm of cranial cavity, also known as intracranial tumor, can originate from brain, meninges, nerve, blood vessel and brain adnexa, or is formed by its hetero-organization of health or Organ relative weight Intracranial invasion, mostly can produce headache, intracranial hypertension and focal symptom.In recent years, intracranial tumor sickness rate is in rising trend, according to statistics, intracranial tumor accounts for 5% of general tumour, account for 70% of pediatric tumor, and other malignant tumor finally has 20-30% and proceeds to intracranial, due to the infiltrative growth that it expands, at intracranial once occupy certain space, no matter its character is optimum or pernicious, intracranial pressure all certainly will be made to raise, compressing cerebral tissue, cause nervus centralis to damage, jeopardize patient vitals.Intracranial tumor can betide any age, is the most common with 20-50 year.Juvenile with posterior cranial fossa and center line tumor more common, be mainly medulloblastoma, craniopharyngioma and ependymoma.Adult is the most common with cerebral hemisphere glioma, if secondly astrocytoma, glioblastoma multiforme, ependymoma etc. are meningioma, pituitary tumor and craniopharyngioma, neurofibroma, cavernous hemangioma, cholesteatoma etc.Primary intracranial tumor incidence rate is without obvious sex difference, and man is slightly more than female.
Clinical manifestation: look its histological type, happening part, the difference of main speed is widely different, and so it has three with feature: increased intracranial pressure.Symptoms of intracranial hypertension accounts in more than 90% Patients with Brain Tumors and occurs, it shows as: brain CT picture.1, headache, Nausea and vomiting, headache multidigit, in forehead and temples, are the aggravation of persistent headache paroxysmal, and headache in morning of being everlasting is heavier, and the intermission can be normal.2, papilloedema and visual deterioration.3, spirit and disturbance of consciousness and other symptoms: dizziness, diplopia, temporary amaurosis, damping off, confusion, spirit uneasiness or indifferent, can epilepsy be there is, even go into a coma.4, changes of vital signs: when moderate and severe acute increased intracranial pressure, often causes breathing, pulse, slows down, and blood pressure raises.Limitation symptom.Local symptom and sign: the position depending primarily on tumor growth, therefore can make the level diagnosis of tumor according to the distinctive sings and symptoms of patient.1, the clinical symptoms of cerebral hemisphere tumor: (1) mental symptom: show as bradykinesia, life is slack, and nearly hypomnesis, even loses, and loses insight and judgment, also can show as short-tempered time serious, emotional or glad more.(2) epilepsy: comprise whole body grand mal and limitation outbreak, the most common with frontal lobe, be followed successively by temporal lobe, top, occipital lobe is the most rare, some cases have tendency before twitching, and as temporal tumour, often have illusion before epilepsy, the tendency such as dizzy, can have the abnormal sensories such as numb limbs and tense tendons before parietal tumour outbreak.(3) tractus pyramidalis infringement symptom: show as tumor offside half body or single limb power is weak or paralysis pathology levy the positive.(4) sensory disturbance: the topognosis showing as tumor contralateral limbs, differentiates for 2 and feels, figure is felt, material is felt, stereognostic obstacle.(5) aphasia: be divided into mobility and sensory aphasia.(6) visual field changes: show as defect of visual field, hemianopsia.2, the clinical manifestation of tumor in sellar area: (1) visual disorder: tumor develops compressing optic chiasma and causes visual deterioration and defect of visual field on saddle, and be usually the main cause that sellar tumor patient comes to go to a doctor, examination of ocular fundus can find primary optic atrophy.(2) endocrine dysfunction: as hypogonadism, male shows as sexual impotence, hyposexuality.Women report is that menstrual phase extends or amenorrhea, growth hormone secretion cross be contained in reach maturity before can cause gigantism, send out after the region between the heart and the diaphragm maturation and show as acromegaly.3, tumors of pineal region clinical symptoms: quadrigemina suffers oppression symptom: embody a concentrated expression of two aspects, that is: look obstacle, reaction of pupil to light and regulate reaction obstacle, tinnitus, deafness; Hold thing shakiness, lurch, eyeball level is trembled, limbs paresis, both sides pyramidal sign; Diabetes insipidus, drowsiness, fat, whole body arrested development, male's observability is precocious.4, the clinical symptoms of tumor of posterior cranial fossa: (1) hemisphaerium cerebelli symptom: main manifestations is affected limb ataxia, and also can occur Ipsilateral hypomyotonia or no-station pole canopy, knee jerk is blunt, and eyeball level is trembled, also can occur that vertical or rotatory is trembled sometimes.(2) vermis cerebelli symptom: main manifestations is the ataxia of trunk and Lower Distal Extremities, during walking, two foots are far isolated, lurch, or roll as drunkard.(3) brain stem symptom: the clinical manifestation of feature is for occurring crossed paralysis, as many in middle cerebral lesion, show as pathological changes side oculomotor paralysis, pon pathological changes, pathological changes branch hole ball abduction and Bekhterev's symptom can be shown as, homonymy face sensory disturbance and dysacousis, can to there is after homonymy lingualis paralysis, throat paralysis, tongue 1/3 sense of taste disappearance etc. in oblongata pathological changes.5, cerebellopontine angle symptom: often show as tinnitus, auditory dysesthesia, dizzy, face is numb, facial spasm, Bekhterev's symptom and hoarseness, and drinking water is choked and coughed, the ataxia of sick side and level shake eye.Progressive symmetric erythrokeratodermia symptom: tumor there will not be pressure symptom in early days sometimes, along with the increase of tumor body, can show as pressure symptom in various degree, the speed increased according to tumor location and grade malignancy, tumor, the also faster or slower of symptom progress extent.
Treatment: (1) operative treatment.For primary tumor, give surgical resection, as far as possible tumor cell is removed totally, avoid the thin cerebral tumor to excise born of the same parents' hypertrophy and be still the most general Therapeutic mode.(2) chemotherapy.The chemotherapy of current cancer makes much progress, but due to the special construction of brain blood brain barrier (BBB), the chemotherapy of cerebroma is still subject to many restrictions, any chemotherapeutics can only pass through blood vessel lining cells by the fat-soluble of medicine, and then enter tumor cell generation effect, such mode influences pharmaceutically-active speed and efficiency.Current clinical conventional chemotherapeutics is nitrosourea alkylating agent BCNU and CCNU, or with PVC scheme (procarbazine+vincristine+CCNU), has certain curative effect, but has delay and the side effect such as accumulation bone marrow depression and pulmonary toxicity, easily produces drug resistance.(3) radiotherapy.Radiation cure be utilize lonizing radiation or gamma-rays, fast neutron ray kills tumor cell, brain cancer pathological changes figure, is called for short radiotherapy.Radiation cure is modal tumor aid treatment means, generally in Post operation 1 to 2 week.Radiation cure mainly utilizes tumor cell more responsive to lonizing radiation, easily be subject to the injury of lonizing radiation to kill tumor cell, general treatment about needs for four to eight weeks, can determine size and the dosage of range of exposures according to different pathologic diagnosis of tumors, differentiation degree and medical imaging check result.To many malignant tumor and position, the deep benign tumor that cannot excise safely, radiation cure is a kind of effective method.Current radiation cure oneself be developed to conformal or locate mode, comprise the radiotherapy of linear accelerator, gal Ma ray localization radiosurgery, Photon Knife etc.But part malignant brain tumor still needs to carry out brain radiation cure or full cranium and vertebra radiotherapy on a large scale.
Application publication number CN104840748A(application number 201510254817.6) Chinese patent literature disclose a kind of have Chinese medicine composition of anti-brain cancer activity and preparation method thereof and its application, this Traditional Chinese medicine compound composition is by Rhizoma Typhonii (processed) 10-30 part, Pseudobulbus Cremastrae Seu Pleiones 15-45 part, Scolopendra 3-9 part, Rhizoma Arisaematis (processed) 10-30 part, Herba Lycopi 10-30 part, Rhizoma Alismatis 10-30 part is made.Application publication number CN104013833A(application number 201410280147.0) Chinese patent literature disclose a kind of pharmaceutical composition for the treatment of the brain cancer, described pharmaceutical composition is made with the raw material of following weight parts: Fructus Viticis 12-24 part, Semen Sinapis Albae 12-24 part, Ramulus Uncariae Cum Uncis 12-24 part, Flos Carthami 12-24 part, Rhizoma Chuanxiong 12-24 part, Radix Salviae Miltiorrhizae 12-24 part, Rhizoma Gastrodiae 12-24 part, Radix Polygoni Multiflori 12-24 part, Rhizoma Cimicifugae 12-24 part, Sanguis Draxonis 9-21 part, Scolopendra 9-21 part, Semen Persicae 9-21 part, Squama Manis 9-21 part, Radix Notoginseng 9-21 part, Borneolum Syntheticum 9-21 part, Indigo Naturalis 9-21 part, Calomelas 9-21 part be combined as active component.Application publication number CN103272109A(application number 201310241277.9) Chinese patent literature disclose a kind of medicament for the treatment of the brain cancer, it comprises the material of following weight proportioning: Rhizoma Arisaematis 20-50 part, Radix Gei japonici 50-70 part, Rhizoma Paridis 12-15 part, Fructus Forsythiae 20-25 part, Spica Prunellae 20-30 part, Radix Rehmanniae 20-25 part, Radix Cudraniae 20-25 part, Rhizoma Dioscoreae 15-21 part, Os Draconis 20-25 part, Semen Juglandis 20-30 part and Rhizoma Pinelliae 15-20 part.
At present, operation is adopted to the treatment of the brain cancer both at home and abroad, the western medicine such as chemotherapy, radiotherapy, GAMA cutter more, but be mostly difficult to cure, and leave serious bad disease.The malignant tumor course of disease is short, and development is fast, according to grade malignancy height excision number or the sensitivity of chemicotherapy, recurrence have early have late; Grow and be difficult to operation in the tumor of the significant points such as brain stem, thalamus and maybe can not perform the operation, GAMA cutter, radiation waits treatment rear section patient's tumor to have to reduce or control growth in the short time, with posterior tuberosity body also can regrowth, recur again; And growth can only part or major part excision in the brain cancer operation of the significant points such as brain stem, operation posterior tuberosity body also can recur again, regrowth.According to interrelated data, intracranial malignant tumor Post operation is put both at home and abroad at present, chemotherapy average viability was less than 1 year, partially optimum glioma, pituitary tumor, craniopharyngioma, the Intracranial Benign Tumor tumor operations such as cholesteatoma not easily excise totally, GAMA cutter, radiotherapy also thoroughly can not kill tumor cell, therefore still can recur again after most of corrective surgery, and the brain injury caused after brain cancer operation also can bring range of conditions to patient, such as headache is dizzy, cerebral palsy, epilepsy, vision and the postoperative sequela of auditory dysesthesia and facial paralysis etc., seriously annoying the physical and mental health of brain cancer patient.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide a kind of Chinese medicine composition and the method for making of curing the brain cancer.The present invention obviously can be alleviated brain cancer symptom and even disappear, and safely, has no side effect, taking convenience, and price is comparatively cheap, avoids the generation of postoperative complication and sequela, can not produce drug resistance, evident in efficacy, not easily recurs.
Technical scheme of the present invention is:
Cure a Chinese medicine composition for the brain cancer, take off the primary raw material medicine stating weight proportion and be prepared from: Spica Prunellae 9-15, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 10-14, Pollen Typhae (decocting a drug wrapped) 6-9, Herba bidentis parviflorae 10-13, Radix et Rhizoma Dysosmatis 8-14, Radix Ilicis Pernyi 7-12, Radix Scrophulariae 9-14, Herba polygoni divaricati 7-13, Bombyx Batryticatus 6-10, Radix Cissi Kerrii 8-13, bracketplant 10-15, Flos Caraganae Franchetianae 8-16, Herba Ecliptae 9-13, Rabdosia rubescens 11-16, Herba seu Fructus Physalis Minimae 7-14, Herba Pellioniae repentis 9-12.
Cure a Chinese medicine composition for the brain cancer, preferred scheme is, takes off the primary raw material medicine stating weight proportion and is prepared from: Spica Prunellae 11-14, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 11-13, Pollen Typhae (decocting a drug wrapped) 7-8, Herba bidentis parviflorae 11-12, Radix et Rhizoma Dysosmatis 9-12, Radix Ilicis Pernyi 8-11, Radix Scrophulariae 10-13, Herba polygoni divaricati 9-12, Bombyx Batryticatus 7-9, Radix Cissi Kerrii 9-12, bracketplant 11-13, Flos Caraganae Franchetianae 11-14, Herba Ecliptae 10-12, Rabdosia rubescens 12-15, Herba seu Fructus Physalis Minimae 10-13, Herba Pellioniae repentis 10-11.
Cure a Chinese medicine composition for the brain cancer, the scheme be more preferably is, takes off the primary raw material medicine stating weight proportion and is prepared from: Spica Prunellae 13, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 12, Pollen Typhae (decocting a drug wrapped) 7.5, Herba bidentis parviflorae 11.5, Radix et Rhizoma Dysosmatis 10, Radix Ilicis Pernyi 10, Radix Scrophulariae 12, Herba polygoni divaricati 11, Bombyx Batryticatus 8, Radix Cissi Kerrii 11, bracketplant 12, Flos Caraganae Franchetianae 13, Herba Ecliptae 11, Rabdosia rubescens 14, Herba seu Fructus Physalis Minimae 11, Herba Pellioniae repentis 10.5.
Present invention also offers the preparation method Chinese medicine composition of the aforementioned treatment brain cancer being made pharmaceutically acceptable powder, pill, Tablet and Capsula agent.
The preparation method of described powder is:
(1) Bombyx Batryticatus is put in pot, fry to surface yellow with slow fire, take out, cool, be ground into fine powder, cross 180 mesh sieves;
(2) by Flos Caraganae Franchetianae and Herba Pellioniae repentis mixing, dry in the shade, grind to the powder altogether, cross 100 mesh sieves, add Mel, the amount of Mel is the amount of the preferred Mel of 1/4-1/2(of Flos Caraganae Franchetianae and Herba Pellioniae repentis two taste crude drug gross weight is 1/3 of Flos Caraganae Franchetianae and Herba Pellioniae repentis two taste crude drug gross weight), stir, place 6-9 hour (preferably placing 7 hours), put into 60 DEG C of baking ovens dry, dry 13-17 hour (preferably dry 15 hours), take out, cool, be ground into fine powder, cross 180 mesh sieves;
(3) 13 taste crude drug except Bombyx Batryticatus, Flos Caraganae Franchetianae and Herba Pellioniae repentis are put into pot, decoct with water twice, amount of water is the 6-8 of 13 taste crude drug gross weights doubly (preferred amount of water is 7.4 times of 13 taste crude drug gross weights), and each decoction 1.5 hours, merges twice medicinal liquid, be condensed into the thick paste (being preferably condensed into the thick paste that relative density is 1.33) that relative density is 1.31-1.34,60 DEG C of dryings 16 hours, take out, cool, be ground into fine powder, cross 180 mesh sieves;
(4) step (1), step (2) and step (3) gained are mixed, with 6g often bag subpackage, sterile packaged and get final product.
The preparation method of described pill is:
(1) Bombyx Batryticatus is put in pot, fry to surface yellow with slow fire, take out, cool, be ground into fine powder, cross 130 mesh sieves;
(2) by Flos Caraganae Franchetianae and Herba Pellioniae repentis mixing, dry in the shade, grind to the powder altogether, cross 100 mesh sieves, add Mel, the amount of Mel is the amount of the preferred Mel of 1/4-1/2(of Flos Caraganae Franchetianae and Herba Pellioniae repentis two taste crude drug gross weight is 1/3 of Flos Caraganae Franchetianae and Herba Pellioniae repentis two taste crude drug gross weight), stir, place 6-9 hour (preferably placing 7 hours), put into 60 DEG C of baking ovens dry, dry 13-17 hour (preferably dry 15 hours), take out, cool, be ground into fine powder, cross 130 mesh sieves;
(3) 13 taste crude drug except Bombyx Batryticatus, Flos Caraganae Franchetianae and Herba Pellioniae repentis are put into pot, decoct with water twice, amount of water is the 6-8 of 13 taste crude drug gross weights doubly (preferred amount of water is 7.4 times of 13 taste crude drug gross weights), and each decoction 1.5 hours, merges twice medicinal liquid, be condensed into the thick paste (being preferably condensed into the thick paste that relative density is 1.33) that relative density is 1.31-1.34,60 DEG C of dryings 16 hours, take out, cool, be ground into fine powder, cross 130 mesh sieves;
(4) step (1), step (2) and step (3) gained are mixed, add refined honey, the weight of refined honey is step (1), the weight of the preferred refined honey of 1/3-3/5(of step (2) and step (3) gained gross weight is 1/2 of step (1), step (2) and step (3) gained gross weight), make the pill that particle diameter is 4mm, drying, to obtain final product.
The preparation method of described tablet is:
(1) Bombyx Batryticatus is put in pot, fry to surface yellow with slow fire, take out, cool, be ground into fine powder, cross 130 mesh sieves;
(2) by Flos Caraganae Franchetianae and Herba Pellioniae repentis mixing, dry in the shade, grind to the powder altogether, cross 100 mesh sieves, add Mel, the amount of Mel is the amount of the preferred Mel of 1/4-1/2(of Flos Caraganae Franchetianae and Herba Pellioniae repentis two taste crude drug gross weight is 1/3 of Flos Caraganae Franchetianae and Herba Pellioniae repentis two taste crude drug gross weight), stir, place 6-9 hour (preferably placing 7 hours), put into 60 DEG C of baking ovens dry, dry 13-17 hour (preferably dry 15 hours), take out, cool, be ground into fine powder, cross 130 mesh sieves;
(3) 13 taste crude drug except Bombyx Batryticatus, Flos Caraganae Franchetianae and Herba Pellioniae repentis are put into pot, decoct with water twice, amount of water is the 6-8 of 13 taste crude drug gross weights doubly (preferred amount of water is 7.4 times of 13 taste crude drug gross weights), and each decoction 1.5 hours, merges twice medicinal liquid, be condensed into the thick paste (being preferably condensed into the thick paste that relative density is 1.33) that relative density is 1.31-1.34,60 DEG C of dryings 16 hours, take out, cool, be ground into fine powder, cross 130 mesh sieves;
(4) step (1), step (2) and step (3) gained are mixed, add cane sugar powder, the weight of cane sugar powder is step (1), the weight of the 1/6-1/4(preferably sucrose powder of step (2) and step (3) gained gross weight is 1/5 of step (1), step (2) and step (3) gained gross weight), stir, be pressed into the tablet of the heavy 0.5g of every sheet, obtain final product.
The preparation method of described capsule is:
(1) Bombyx Batryticatus is put in pot, fry to surface yellow with slow fire, take out, cool, be ground into fine powder, cross 130 mesh sieves;
(2) by Flos Caraganae Franchetianae and Herba Pellioniae repentis mixing, dry in the shade, grind to the powder altogether, cross 100 mesh sieves, add Mel, the amount of Mel is the amount of the preferred Mel of 1/4-1/2(of Flos Caraganae Franchetianae and Herba Pellioniae repentis two taste crude drug gross weight is 1/3 of Flos Caraganae Franchetianae and Herba Pellioniae repentis two taste crude drug gross weight), stir, place 6-9 hour (preferably placing 7 hours), put into 60 DEG C of baking ovens dry, dry 13-17 hour (preferably dry 15 hours), take out, cool, be ground into fine powder, cross 130 mesh sieves;
(3) 13 taste crude drug except Bombyx Batryticatus, Flos Caraganae Franchetianae and Herba Pellioniae repentis are put into pot, decoct with water twice, amount of water is the 6-8 of 13 taste crude drug gross weights doubly (preferred amount of water is 7.4 times of 13 taste crude drug gross weights), and each decoction 1.5 hours, merges twice medicinal liquid, be condensed into the thick paste (being preferably condensed into the thick paste that relative density is 1.33) that relative density is 1.31-1.34,60 DEG C of dryings 16 hours, take out, cool, be ground into fine powder, cross 130 mesh sieves;
(4) step (1), step (2) and step (3) gained are mixed, in incapsulating, medicated powder 0.4g is housed in every capsules, obtains final product.
Chinese medicine composition scientific formula provided by the invention, the preparation method of various dosage form is simple, products obtained therefrom taking convenience, is easy to carry.In addition, excellent results of the present invention also shows:
, have no side effect 1, safely;
2, price is comparatively cheap, alleviates patient economy burden;
3, avoid the generation of postoperative complication and sequela, can not drug resistance be produced;
4, there is effect of liver and kidney tonifying, blood circulation promoting and blood stasis dispelling, dissipating phlegm and resolving masses, removing heat from blood YIN nourishing, eliminating fire and detoxication, QI invigorating kidney tonifying, hard masses softening and resolving, heat-clearing and toxic substances removing, mind tranquilizing and the heart calming, obviously can alleviate brain cancer symptom and even disappear, evident in efficacy, not easily recur.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1cure a Chinese medicine composition for the brain cancer, the primary raw material medicine getting following weight parts is prepared from (every part is 200g): Spica Prunellae 9 parts, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 10 parts, Pollen Typhae (decocting a drug wrapped) 6 parts, Herba bidentis parviflorae 10 parts, Radix et Rhizoma Dysosmatis 8 parts, Radix Ilicis Pernyi 7 parts, Radix Scrophulariae 9 parts, Herba polygoni divaricati 7 parts, Bombyx Batryticatus 6 parts, Radix Cissi Kerrii 8 parts, bracketplant 10 parts, Flos Caraganae Franchetianae 8 parts, Herba Ecliptae 9 parts, Rabdosia rubescens 11 parts, Herba seu Fructus Physalis Minimae 7 parts, Herba Pellioniae repentis 9 parts.
The instructions of taking of the Chinese medicine composition composition powders of the above-mentioned treatment brain cancer is:
(1) Bombyx Batryticatus is put in pot, fry to surface yellow with slow fire, take out, cool, be ground into fine powder, cross 180 mesh sieves;
(2) by Flos Caraganae Franchetianae and Herba Pellioniae repentis mixing, dry in the shade, grind to the powder altogether, cross 100 mesh sieves, add Mel, the amount of Mel is 1/4 of Flos Caraganae Franchetianae and Herba Pellioniae repentis two taste crude drug gross weight, stir, place 6 hours, put into 60 DEG C of baking ovens dry, dry 13 hours, take out, cool, be ground into fine powder, cross 180 mesh sieves;
(3) 13 taste crude drug except Bombyx Batryticatus, Flos Caraganae Franchetianae and Herba Pellioniae repentis are put into pot, decoct with water twice, amount of water is 6 times of 13 taste crude drug gross weights, and each decoction 1.5 hours, merges twice medicinal liquid, be condensed into the thick paste that relative density is 1.31,60 DEG C of dryings 16 hours, take out, cool, be ground into fine powder, cross 180 mesh sieves;
(4) step (1), step (2) and step (3) gained are mixed, with 6g often bag subpackage, sterile packaged and get final product.
The instructions of taking that gained of the present invention cures the Chinese medicine composition composition powders of the brain cancer is: oral, one day twice, each 6g, boiled water was taken after mixing it with water.
embodiment 2cure a Chinese medicine composition for the brain cancer, the primary raw material medicine getting following weight parts is prepared from (every part is 200g): Spica Prunellae 15 parts, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 14 parts, Pollen Typhae (decocting a drug wrapped) 9 parts, Herba bidentis parviflorae 13 parts, Radix et Rhizoma Dysosmatis 14 parts, Radix Ilicis Pernyi 12 parts, Radix Scrophulariae 14 parts, Herba polygoni divaricati 13 parts, Bombyx Batryticatus 10 parts, Radix Cissi Kerrii 13 parts, bracketplant 15 parts, Flos Caraganae Franchetianae 16 parts, Herba Ecliptae 13 parts, Rabdosia rubescens 16 parts, Herba seu Fructus Physalis Minimae 14 parts, Herba Pellioniae repentis 12 parts.
The preparation method of the Chinese medicine composition pill of the above-mentioned treatment brain cancer is:
(1) Bombyx Batryticatus is put in pot, fry to surface yellow with slow fire, take out, cool, be ground into fine powder, cross 130 mesh sieves;
(2) by Flos Caraganae Franchetianae and Herba Pellioniae repentis mixing, dry in the shade, grind to the powder altogether, cross 100 mesh sieves, add Mel, the amount of Mel is 1/3 of Flos Caraganae Franchetianae and Herba Pellioniae repentis two taste crude drug gross weight, stir, place 7 hours, put into 60 DEG C of baking ovens dry, dry 15 hours, take out, cool, be ground into fine powder, cross 130 mesh sieves;
(3) 13 taste crude drug except Bombyx Batryticatus, Flos Caraganae Franchetianae and Herba Pellioniae repentis are put into pot, decoct with water twice, amount of water is 7.4 times of 13 taste crude drug gross weights, and each decoction 1.5 hours, merges twice medicinal liquid, be condensed into the thick paste that relative density is 1.33,60 DEG C of dryings 16 hours, take out, cool, be ground into fine powder, cross 130 mesh sieves;
(4) step (1), step (2) and step (3) gained are mixed, add refined honey, the weight of refined honey is 1/2 of step (1), step (2) and step (3) gained gross weight, makes the pill that particle diameter is 4mm, dry, to obtain final product.
model case one:week XX, man, 55 years old.Before 1 year, the symptoms such as myasthenia of limbs appears in patient, hypomnesis, are diagnosed as the brain cancer to local hospital inspection, row excision, postoperation radiotherapy 20 times.Before 1 month, above-mentioned symptom recurs, and Sui Lai institute goes to a doctor.Patient's headache and dizzy, myasthenia of limbs, hypomnesis.Head mri is shown: after the brain tumor surgery of left side.Be diagnosed as brain cancer recurrence.Take the Chinese medicine composition pill that the present embodiment gained cures the brain cancer, three times on the one, each 4 balls, warm water takes.Take one month, sb.'s illness took a favorable turn.Take three months, all diseases disappear.Check cases of complete remission.Follow up a case by regular visits to and do not recur.
embodiment 3cure a Chinese medicine composition for the brain cancer, the primary raw material medicine getting following weight parts is prepared from (every part is 200g): Spica Prunellae 11 parts, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 11 parts, Pollen Typhae (decocting a drug wrapped) 7 parts, Herba bidentis parviflorae 11 parts, Radix et Rhizoma Dysosmatis 9 parts, Radix Ilicis Pernyi 8 parts, Radix Scrophulariae 10 parts, Herba polygoni divaricati 9 parts, Bombyx Batryticatus 7 parts, Radix Cissi Kerrii 9 parts, bracketplant 11 parts, Flos Caraganae Franchetianae 11 parts, Herba Ecliptae 10 parts, Rabdosia rubescens 12 parts, Herba seu Fructus Physalis Minimae 10 parts, Herba Pellioniae repentis 10 parts.
The preparation method of the Chinese medicine composition tablet of the above-mentioned treatment brain cancer is:
(1) Bombyx Batryticatus is put in pot, fry to surface yellow with slow fire, take out, cool, be ground into fine powder, cross 130 mesh sieves;
(2) by Flos Caraganae Franchetianae and Herba Pellioniae repentis mixing, dry in the shade, grind to the powder altogether, cross 100 mesh sieves, add Mel, the amount of Mel is 1/3 of Flos Caraganae Franchetianae and Herba Pellioniae repentis two taste crude drug gross weight, stir, place 7 hours, put into 60 DEG C of baking ovens dry, dry 15 hours, take out, cool, be ground into fine powder, cross 130 mesh sieves;
(3) 13 taste crude drug except Bombyx Batryticatus, Flos Caraganae Franchetianae and Herba Pellioniae repentis are put into pot, decoct with water twice, amount of water is 7.4 times of 13 taste crude drug gross weights, and each decoction 1.5 hours, merges twice medicinal liquid, be condensed into the thick paste that relative density is 1.33,60 DEG C of dryings 16 hours, take out, cool, be ground into fine powder, cross 130 mesh sieves;
(4) step (1), step (2) and step (3) gained are mixed, add cane sugar powder, the weight of cane sugar powder is 1/5 of step (1), step (2) and step (3) gained gross weight, stirs, and is pressed into the tablet of the heavy 0.5g of every sheet, obtains final product.
model case two:king XX, female, 33 years old.Before half a year, there is feeling of fullness in the head of having a headache in patient, left eyelid is sagging, nausea and vomiting, shows at local hospital head B-sonography: suprasellar cistern space occupying lesion, Optic-hypothalamic Gliomas.Because patient refuses operative treatment, then give Drug therapy.After treatment, without being clearly better.Then to our hospital.Patient has a headache feeling of fullness in the head, and left eyelid is sagging, irritable, nausea and vomiting, and tongue is dim red, yellow fur, wiry and frequent pulse.Take the Chinese medicine composition tablet that the present embodiment gained cures the brain cancer, three times on the one, each 2, warm water takes.After taking 1 month, sb.'s illness took a favorable turn, and left eye can be opened voluntarily, but palpebral fissure is less.After taking 3 months, symptom disappears completely, check cases of complete remission.Follow up a case by regular visits to and do not recur.
embodiment 4cure a Chinese medicine composition for the brain cancer, the primary raw material medicine getting following weight parts is prepared from (every part is 200g): Spica Prunellae 14 parts, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 13 parts, Pollen Typhae (decocting a drug wrapped) 8 parts, Herba bidentis parviflorae 12 parts, Radix et Rhizoma Dysosmatis 12 parts, Radix Ilicis Pernyi 11 parts, Radix Scrophulariae 13 parts, Herba polygoni divaricati 12 parts, Bombyx Batryticatus 9 parts, Radix Cissi Kerrii 12 parts, bracketplant 13 parts, Flos Caraganae Franchetianae 14 parts, Herba Ecliptae 12 parts, Rabdosia rubescens 15 parts, Herba seu Fructus Physalis Minimae 13 parts, Herba Pellioniae repentis 11 parts.
The preparation method of the Chinese medicinal composition capsules agent of the above-mentioned treatment brain cancer is:
(1) Bombyx Batryticatus is put in pot, fry to surface yellow with slow fire, take out, cool, be ground into fine powder, cross 130 mesh sieves;
(2) by Flos Caraganae Franchetianae and Herba Pellioniae repentis mixing, dry in the shade, grind to the powder altogether, cross 100 mesh sieves, add Mel, the amount of Mel is 1/3 of Flos Caraganae Franchetianae and Herba Pellioniae repentis two taste crude drug gross weight, stir, place 7 hours, put into 60 DEG C of baking ovens dry, dry 15 hours, take out, cool, be ground into fine powder, cross 130 mesh sieves;
(3) 13 taste crude drug except Bombyx Batryticatus, Flos Caraganae Franchetianae and Herba Pellioniae repentis are put into pot, decoct with water twice, amount of water is 7.4 times of 13 taste crude drug gross weights, and each decoction 1.5 hours, merges twice medicinal liquid, be condensed into the thick paste that relative density is 1.33,60 DEG C of dryings 16 hours, take out, cool, be ground into fine powder, cross 130 mesh sieves;
(4) step (1), step (2) and step (3) gained are mixed, in incapsulating, medicated powder 0.4g is housed in every capsules, obtains final product.
model case three:hole XX, man, 62 years old.Before 2 years, having a dizzy spell appears in patient, the symptoms such as tinnitus, is diagnosed as the brain cancer in local hospital inspection.Because operation risk is large, patient refuses operation, takes multiple curing oncoma medicine, DeGrain.Under the introduction of friend, to our hospital.Patient has a dizzy spell, tinnitus, visual disorder, soreness of the waist and knees, lazy speech of breathing hard, deep,thready and forceless pulse.Wardrobe portion nuclear magnetic scanning finds the tumor of 2cm-3cm size.Be diagnosed as the brain cancer.Take the Chinese medicinal composition capsules agent that the present embodiment gained cures the brain cancer, three times on the one, each 2, warm water takes.After taking 1 month, symptom obviously alleviates.After taking 3 months, symptom disappears completely, and to examination in hospital, tumor regression is to 0.4 × 0.6cm.After taking 5 months, cases of complete remission.Follow up a case by regular visits to so far, do not recur.
embodiment 5cure a Chinese medicine composition for the brain cancer, the primary raw material medicine getting following weight parts is prepared from (every part is 200g): Spica Prunellae 13 parts, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 12 parts, Pollen Typhae (decocting a drug wrapped) 7.5 parts, Herba bidentis parviflorae 11.5 parts, Radix et Rhizoma Dysosmatis 10 parts, Radix Ilicis Pernyi 10 parts, Radix Scrophulariae 12 parts, Herba polygoni divaricati 11 parts, Bombyx Batryticatus 8 parts, Radix Cissi Kerrii 11 parts, bracketplant 12 parts, Flos Caraganae Franchetianae 13 parts, Herba Ecliptae 11 parts, Rabdosia rubescens 14 parts, Herba seu Fructus Physalis Minimae 11 parts, Herba Pellioniae repentis 10.5 parts.
The preparation method of the Chinese medicine composition composition powders of the above-mentioned treatment brain cancer is:
(1) Bombyx Batryticatus is put in pot, fry to surface yellow with slow fire, take out, cool, be ground into fine powder, cross 180 mesh sieves;
(2) by Flos Caraganae Franchetianae and Herba Pellioniae repentis mixing, dry in the shade, grind to the powder altogether, cross 100 mesh sieves, add Mel, the amount of Mel is 1/3 of Flos Caraganae Franchetianae and Herba Pellioniae repentis two taste crude drug gross weight, stir, place 7 hours, put into 60 DEG C of baking ovens dry, dry 15 hours, take out, cool, be ground into fine powder, cross 180 mesh sieves;
(3) 13 taste crude drug except Bombyx Batryticatus, Flos Caraganae Franchetianae and Herba Pellioniae repentis are put into pot, decoct with water twice, amount of water is 7.4 times of 13 taste crude drug gross weights, and each decoction 1.5 hours, merges twice medicinal liquid, be condensed into the thick paste that relative density is 1.33,60 DEG C of dryings 16 hours, take out, cool, be ground into fine powder, cross 180 mesh sieves;
(4) step (1), step (2) and step (3) gained are mixed, with 6g often bag subpackage, sterile packaged and get final product.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Spica Prunellae: base is former: be the dry fruit ear of labiate Spica Prunellae.The property of medicine: pungent, bitter, cold.Return liver, gallbladder meridian.Function cures mainly: relieve inflammation or internal heat, improving eyesight, eliminating stagnation, detumescence.For conjunctival congestion and swelling pain, order pearl nyctalgia, has a headache dizzy, scrofula, goiter, and acute mastitis swells and ache, thyromegaly, tuberculous lymphadenitis, cyclomastopathy, hypertension.
Crepis crocea Babc.(C.turczaninowii C.A.Mey.): base is former: be the root that outstanding zhang of feverfew Folium Bambusae ten thousand is dark.The property of medicine: bitter in the mouth; Sweet; Warm in nature.Function cures mainly: liver and kidney tonifying; Invigorating spleen to remove dampness.Master has a dizzy spell; Soreness of the waist and knees; Edema; Leukorrhagia infantile malnutrition; Hypogalactia.
Pollen Typhae (decocting a drug wrapped): base is former: be the pollen that Typhaceae plant typha angustifolia, common cattail, typha orientalis and long bud are fragrant.The property of medicine: sweet in the mouth, micro-pungent; Property is put down.Return liver, the heart, spleen channel.Function cures mainly: hemostasis; Blood stasis dispelling; Diuresis.Main haematemesis; Spitting of blood; Epistaxis; Standby dysentery; Have blood in stool; Metrorrhagia; Traumatic hemorrhage; Trusted subordinate's pain; Amenorrhea is suffered from abdominal pain; Puerperal the stasis of blood pain; Dysmenorrhea; Tumbling and swelling; Blood strangury and dry pain; Leukorrhagia; Congenital deformity of the tongue; Aphtha; Ting ear; Uncontrolled urination is itched.
Herba bidentis parviflorae: base is former: be the herb of feverfew Herba bidentis parviflorae.The property of medicine: mildly bitter flavor; Micro-pungent; Cool in nature.Function cures mainly: clearing away heat-damp and promoting diuresis; Removing toxic substances and promoting subsidence of swelling; Promoting blood circulation and hemostasis.Main dysentery; To have loose bowels edema; Cough; Asthma; Tonsillitis; Hemoptysis; Hematuria; Carbuncle furuncle and phyma poison; Herpes zoster; Treating swelling and pain by traumatic injury; Traumatic hemorrhage.
Radix et Rhizoma Dysosmatis: base is former: be the root and rhizome of Berberidaceae plant Radix et Rhizoma Dysosmatis, Dysosma Pleiantha and dysosma veitchii Fu.The property of medicine: bitter in the mouth; Pungent; Cool in nature; Poisonous.Return lung, Liver Channel.Function cures mainly: dissipating phlegm and resolving masses; Stasis-dispelling and pain-killing; Heat-clearing and toxic substances removing.Main cough; Laryngopharynx swelling and pain; Scrofula; Goiter; Carbuncle; Furuncle; Venom; Traumatic injury; Arthromyodynia.
Radix Ilicis Pernyi: base is former: be the root of holly plant Ilex pernyi.The property of medicine: bitter; Cold.Return lung meridian.Function cures mainly: clearing away lung-heat to relieve cough; Sore-throat relieving; Improving eyesight.Main cough due to lung-heat; Spitting of blood; Laryngopharynx swelling and pain; Pterygium.
Radix Scrophulariae: base is former: be the dry root of goatweed Radix Scrophulariae.The property of medicine: sweet, bitter, salty, is slightly cold.Return lung, stomach, kidney channel.Function cures mainly: removing heat from blood YIN nourishing, eliminating fire and detoxication.For consumption of YIN caused by febrile disease, crimson tongue excessive thirst, maculae caused by violent heat pathogen, constipation is hindered in Tianjin, hectic fever due to YIN-deficiency chronic cough, conjunctival congestion, pharyngalgia, and scrofula is sick, diphtheria, carbuncle sore tumefacting virus.
Herba polygoni divaricati: base is former: be the herb of polygonaceae plant fork point knotweed.The property of medicine: acid; Bitter; Cool in nature.Function cures mainly: heat clearing and damp drying; Hard masses softening and resolving.Main damp-heat diarrhea; Dysentery; Goiter scrofula.
Bombyx Batryticatus: have another name called Bombyx Batryticatus, flying worm, Bombyx Batryticatus worm, the larva belonging to animal bombyx mori for Bombycidae silkworm infects muscardine and ossified Scorpio.The property of medicine: this product is slightly cylindrical, how bending shrinkage, surperficial lark, matter is hard and crisp, frangibility, acrid in the mouth, salty, and property is put down.Composition: Bombyx Batryticatus containing protein, oxamidic acid., and contains lysine, leucine, aspartic acid etc. 17 seed amino acid.According to modern pharmacological research find, this medical instrument have expelling wind and relieving convulsion, dissipating phlegm and resolving masses, resolving toxin and disinhibiting the throat, convulsion, hypoglycemic effect, for apoplexy, migraine and general headache, laryngopharynx swelling and pain, rubella etc.
Radix Cissi Kerrii: base is former: be the tuber of vitaceae Cissus repens.The property of medicine: bitter; Micro-pungent; Cool in nature.GUIXIN, kidney channel.Function cures mainly: promoting blood circulation to remove obstruction in the collateral; Dissipating phlegm and resolving masses; Removing toxicity for eliminating carbuncles.Main traumatic injury; Rheumatic arthralgia; Scrofula sucutaneous nodule; Carbuncle sore tumefacting virus; Venom.
Bracketplant: base is former: be herb or the root of liliaceous plant bracketplant.The property of medicine: sweet in the mouth; Micro-hardship; Cool in nature.Function cures mainly: preventing phlegm from forming and stopping coughing; Dissipating blood stasis for subsidence of swelling; Heat-clearing and toxic substances removing.Main phlegm-heat cough; Traumatic injury; Fracture; Carbuncle; Hemorrhoid; Burn.
Flos Caraganae Franchetianae: base is former: be the flower of leguminous plant Yunnan caragana.The property of medicine: sweet micro-hardship; Flat.Return kidney channel.Function cures mainly: QI invigorating kidney tonifying.Main tinnitus due to deficiency of the kidney, dizziness and blurred vision, headache, pulmonary tuberculosis cough, infantile malnutrition.
Herba Ecliptae: base is former: the herb of feverfew Eclipta prostrata.The property of medicine: sweet in the mouth; Acid; Cool in nature.Return liver, kidney channel.Function cures mainly: liver and kidney tonifying; Cooling blood for hemostasis.Main deficiency of the liver and kindey; Have a dizzy spell; Early whitening of beard and hair; Spit blood; Spitting of blood; Epistaxis; Have blood in stool; Dysentery; Collapse; Leak; Traumatic hemorrhage.
Rabdosia rubescens: base is former: for labiate is cracked rice the herb of fork.The property of medicine: bitter in the mouth; Sweet; Cold nature.Function cures mainly: heat-clearing and toxic substances removing; Promoting blood circulation and stopping pain.Main laryngopharynx swelling and pain; Headache due to common cold; Tracheitis; Chronic hepatitis; Rheumatic arthritis; Snake bite and insect sting.
Herba seu Fructus Physalis Minimae: base is former: be herb or the fruit of the little Calyx seu fructus physalis of plant of Solanaceae.The property of medicine: bitter in the mouth; Cool in nature.Function cures mainly: clearing away heat-damp and promoting diuresis; Expelling phlegm for arresting cough, hard masses softening and resolving.Main jaundice due to damp-heat, dysuria, chronic cough and asthma, infantile malnutrition, scrofula, epidemic blisters, eczema, furuncle and phyma.
Herba Pellioniae repentis: base is former: be the herb of contrayerva Herba Pellioniae repentis.The property of medicine: sweet; Micro-puckery; Cool in nature.Return liver, the heart, spleen channel.Function cures mainly: clearing away heat-damp and promoting diuresis; Mind tranquilizing and the heart calming.Main damp and hot yellow cellulitis; Ascites; Insomnia; Forgetful; Allergic dermatitis; Ulcer of the lower limb; Furuncle toxic swelling.
test example 1gained of the present invention cures the clinical practice of the Chinese medicine composition (embodiment 5) of the brain cancer: in June ,-2010 in June, 2008, and the brain cancer patient all made a definite diagnosis through pathology 5 hospital's screening 210 examples carries out clinical observation.Wherein male 125 example, women 85 example, 19 years old ~ 62 years old age.All cases all take the Chinese medicine composition that gained of the present invention cures pulmonary carcinoma, and using method: oral, one day twice, each 6g, boiled water was taken after mixing it with water, and within 1 month, is a course for the treatment of.
Curative effect situation criterion: complete incidence graph (CR): cases of complete remission, maintains more than 4 weeks; Partial rcsponse (PR): tumor regression more than 50%, and maintain more than 4 weeks; Stable disease (SD): tumor regression < 50%, or tumor increases < 25%, and maintain more than 4 weeks; Disease progression (PD): tumor increases > 25% or occurs new pathological changes.Always effectively comprise complete incidence graph and partial rcsponse.Result is as shown in table 1.
Table 1: gained of the present invention cures the Chinese medicine composition compliance test result [example (%)] of the brain cancer
The present invention is primary raw material medicine with Spica Prunellae, Crepis crocea Babc.(C.turczaninowii C.A.Mey.), Pollen Typhae and Herba bidentis parviflorae etc., makes the Chinese medicine composition of curing the brain cancer.In side, Spica Prunellae relieves inflammation or internal heat, improving eyesight, eliminating stagnation, detumescence.Crepis crocea Babc.(C.turczaninowii C.A.Mey.) liver and kidney tonifying; Invigorating spleen to remove dampness.Pollen Typhae is stopped blooding; Blood stasis dispelling; Diuresis.Herba bidentis parviflorae clearing away heat-damp and promoting diuresis; Removing toxic substances and promoting subsidence of swelling; Promoting blood circulation and hemostasis.Radix et Rhizoma Dysosmatis dissipating phlegm and resolving masses; Stasis-dispelling and pain-killing; Heat-clearing and toxic substances removing.Radix Ilicis Pernyi clearing away lung-heat to relieve cough; Sore-throat relieving; Improving eyesight.Radix Scrophulariae removing heat from blood YIN nourishing, eliminating fire and detoxication.Herba polygoni divaricati heat clearing and damp drying; Hard masses softening and resolving.Bombyx Batryticatus have expelling wind and relieving convulsion, dissipating phlegm and resolving masses, resolving toxin and disinhibiting the throat, convulsion, hypoglycemic effect.Radix Cissi Kerrii promoting blood circulation to remove obstruction in the collateral; Dissipating phlegm and resolving masses; Removing toxicity for eliminating carbuncles.Bracketplant preventing phlegm from forming and stopping coughing; Dissipating blood stasis for subsidence of swelling; Heat-clearing and toxic substances removing.Flos Caraganae Franchetianae QI invigorating kidney tonifying.Herba Ecliptae liver and kidney tonifying; Cooling blood for hemostasis.Rabdosia rubescens heat-clearing and toxic substances removing; Promoting blood circulation and stopping pain.Herba seu Fructus Physalis Minimae clearing away heat-damp and promoting diuresis; Expelling phlegm for arresting cough, hard masses softening and resolving.
Herba Pellioniae repentis clearing away heat-damp and promoting diuresis; Mind tranquilizing and the heart calming.Many medicines share, mutual coordination, plays the effect of liver and kidney tonifying, blood circulation promoting and blood stasis dispelling, dissipating phlegm and resolving masses, removing heat from blood YIN nourishing, eliminating fire and detoxication, QI invigorating kidney tonifying, hard masses softening and resolving, heat-clearing and toxic substances removing, mind tranquilizing and the heart calming altogether, obviously can alleviate brain cancer symptom and even disappear, evident in efficacy, not easily recur.
Finally it should be noted that, embodiment is the detailed description of the invention of optimum of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.

Claims (10)

1. cure a Chinese medicine composition for the brain cancer, it is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Spica Prunellae 9-15, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 10-14, Pollen Typhae (decocting a drug wrapped) 6-9, Herba bidentis parviflorae 10-13, Radix et Rhizoma Dysosmatis 8-14, Radix Ilicis Pernyi 7-12, Radix Scrophulariae 9-14, Herba polygoni divaricati 7-13, Bombyx Batryticatus 6-10, Radix Cissi Kerrii 8-13, bracketplant 10-15, Flos Caraganae Franchetianae 8-16, Herba Ecliptae 9-13, Rabdosia rubescens 11-16, Herba seu Fructus Physalis Minimae 7-14, Herba Pellioniae repentis 9-12.
2. Chinese medicine composition of curing the brain cancer as claimed in claim 1, is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Spica Prunellae 11-14, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 11-13, Pollen Typhae (decocting a drug wrapped) 7-8, Herba bidentis parviflorae 11-12, Radix et Rhizoma Dysosmatis 9-12, Radix Ilicis Pernyi 8-11, Radix Scrophulariae 10-13, Herba polygoni divaricati 9-12, Bombyx Batryticatus 7-9, Radix Cissi Kerrii 9-12, bracketplant 11-13, Flos Caraganae Franchetianae 11-14, Herba Ecliptae 10-12, Rabdosia rubescens 12-15, Herba seu Fructus Physalis Minimae 10-13, Herba Pellioniae repentis 10-11.
3. Chinese medicine composition of curing the brain cancer as claimed in claim 1, is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Spica Prunellae 13, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 12, Pollen Typhae (decocting a drug wrapped) 7.5, Herba bidentis parviflorae 11.5, Radix et Rhizoma Dysosmatis 10, Radix Ilicis Pernyi 10, Radix Scrophulariae 12, Herba polygoni divaricati 11, Bombyx Batryticatus 8, Radix Cissi Kerrii 11, bracketplant 12, Flos Caraganae Franchetianae 13, Herba Ecliptae 11, Rabdosia rubescens 14, Herba seu Fructus Physalis Minimae 11, Herba Pellioniae repentis 10.5.
4. the Chinese medicine composition of the treatment brain cancer as described in as arbitrary in claims 1 to 3, it is characterized in that, the Chinese medicine composition of this treatment brain cancer is made pharmaceutically acceptable powder, and the preparation method of described powder is:
(1) Bombyx Batryticatus is put in pot, fry to surface yellow with slow fire, take out, cool, be ground into fine powder, cross 180 mesh sieves;
(2) by Flos Caraganae Franchetianae and Herba Pellioniae repentis mixing, dry in the shade, grind to the powder altogether, cross 100 mesh sieves, add Mel, the amount of Mel is the 1/4-1/2 of Flos Caraganae Franchetianae and Herba Pellioniae repentis two taste crude drug gross weight, stir, place 6-9 hour, put into 60 DEG C of baking ovens dry, dry 13-17 hour, take out, cool, be ground into fine powder, cross 180 mesh sieves;
(3) 13 taste crude drug except Bombyx Batryticatus, Flos Caraganae Franchetianae and Herba Pellioniae repentis are put into pot, decoct with water twice, amount of water is the 6-8 of 13 taste crude drug gross weights doubly (preferred amount of water is 7.4 times of 13 taste crude drug gross weights), and each decoction 1.5 hours, merges twice medicinal liquid, be condensed into the thick paste (being preferably condensed into the thick paste that relative density is 1.33) that relative density is 1.31-1.34,60 DEG C of dryings 16 hours, take out, cool, be ground into fine powder, cross 180 mesh sieves;
(4) step (1), step (2) and step (3) gained are mixed, with 6g often bag subpackage, sterile packaged and get final product.
5. the Chinese medicine composition of the treatment brain cancer as described in as arbitrary in claims 1 to 3, it is characterized in that, the Chinese medicine composition of this treatment brain cancer is made pharmaceutically acceptable pill, and the preparation method of described pill is:
(1) Bombyx Batryticatus is put in pot, fry to surface yellow with slow fire, take out, cool, be ground into fine powder, cross 130 mesh sieves;
(2) by Flos Caraganae Franchetianae and Herba Pellioniae repentis mixing, dry in the shade, grind to the powder altogether, cross 100 mesh sieves, add Mel, the amount of Mel is the amount of the preferred Mel of 1/4-1/2(of Flos Caraganae Franchetianae and Herba Pellioniae repentis two taste crude drug gross weight is 1/3 of Flos Caraganae Franchetianae and Herba Pellioniae repentis two taste crude drug gross weight), stir, place 6-9 hour (preferably placing 7 hours), put into 60 DEG C of baking ovens dry, dry 13-17 hour (preferably dry 15 hours), take out, cool, be ground into fine powder, cross 130 mesh sieves;
(3) 13 taste crude drug except Bombyx Batryticatus, Flos Caraganae Franchetianae and Herba Pellioniae repentis are put into pot, decoct with water twice, amount of water is the 6-8 of 13 taste crude drug gross weights doubly (preferred amount of water is 7.4 times of 13 taste crude drug gross weights), and each decoction 1.5 hours, merges twice medicinal liquid, be condensed into the thick paste (being preferably condensed into the thick paste that relative density is 1.33) that relative density is 1.31-1.34,60 DEG C of dryings 16 hours, take out, cool, be ground into fine powder, cross 130 mesh sieves;
(4) step (1), step (2) and step (3) gained are mixed, add refined honey, the weight of refined honey is step (1), the weight of the preferred refined honey of 1/3-3/5(of step (2) and step (3) gained gross weight is 1/2 of step (1), step (2) and step (3) gained gross weight), make the pill that particle diameter is 4mm, drying, to obtain final product.
6. the Chinese medicine composition of the treatment brain cancer as described in as arbitrary in claims 1 to 3, it is characterized in that, the Chinese medicine composition of this treatment brain cancer is made pharmaceutically acceptable tablet, and the preparation method of described tablet is:
(1) Bombyx Batryticatus is put in pot, fry to surface yellow with slow fire, take out, cool, be ground into fine powder, cross 130 mesh sieves;
(2) by Flos Caraganae Franchetianae and Herba Pellioniae repentis mixing, dry in the shade, grind to the powder altogether, cross 100 mesh sieves, add Mel, the amount of Mel is the amount of the preferred Mel of 1/4-1/2(of Flos Caraganae Franchetianae and Herba Pellioniae repentis two taste crude drug gross weight is 1/3 of Flos Caraganae Franchetianae and Herba Pellioniae repentis two taste crude drug gross weight), stir, place 6-9 hour (preferably placing 7 hours), put into 60 DEG C of baking ovens dry, dry 13-17 hour (preferably dry 15 hours), take out, cool, be ground into fine powder, cross 130 mesh sieves;
(3) 13 taste crude drug except Bombyx Batryticatus, Flos Caraganae Franchetianae and Herba Pellioniae repentis are put into pot, decoct with water twice, amount of water is the 6-8 of 13 taste crude drug gross weights doubly (preferred amount of water is 7.4 times of 13 taste crude drug gross weights), and each decoction 1.5 hours, merges twice medicinal liquid, be condensed into the thick paste (being preferably condensed into the thick paste that relative density is 1.33) that relative density is 1.31-1.34,60 DEG C of dryings 16 hours, take out, cool, be ground into fine powder, cross 130 mesh sieves;
(4) step (1), step (2) and step (3) gained are mixed, add cane sugar powder, the weight of cane sugar powder is step (1), the weight of the 1/6-1/4(preferably sucrose powder of step (2) and step (3) gained gross weight is 1/5 of step (1), step (2) and step (3) gained gross weight), stir, be pressed into the tablet of the heavy 0.5g of every sheet, obtain final product.
7. the Chinese medicine composition of the treatment brain cancer as described in as arbitrary in claims 1 to 3, it is characterized in that, the Chinese medicine composition of this treatment brain cancer is made pharmaceutically acceptable capsule, and the preparation method of described capsule is:
(1) Bombyx Batryticatus is put in pot, fry to surface yellow with slow fire, take out, cool, be ground into fine powder, cross 130 mesh sieves;
(2) by Flos Caraganae Franchetianae and Herba Pellioniae repentis mixing, dry in the shade, grind to the powder altogether, cross 100 mesh sieves, add Mel, the amount of Mel is the amount of the preferred Mel of 1/4-1/2(of Flos Caraganae Franchetianae and Herba Pellioniae repentis two taste crude drug gross weight is 1/3 of Flos Caraganae Franchetianae and Herba Pellioniae repentis two taste crude drug gross weight), stir, place 6-9 hour (preferably placing 7 hours), put into 60 DEG C of baking ovens dry, dry 13-17 hour (preferably dry 15 hours), take out, cool, be ground into fine powder, cross 130 mesh sieves;
(3) 13 taste crude drug except Bombyx Batryticatus, Flos Caraganae Franchetianae and Herba Pellioniae repentis are put into pot, decoct with water twice, amount of water is the 6-8 of 13 taste crude drug gross weights doubly (preferred amount of water is 7.4 times of 13 taste crude drug gross weights), and each decoction 1.5 hours, merges twice medicinal liquid, be condensed into the thick paste (being preferably condensed into the thick paste that relative density is 1.33) that relative density is 1.31-1.34,60 DEG C of dryings 16 hours, take out, cool, be ground into fine powder, cross 130 mesh sieves;
(4) step (1), step (2) and step (3) gained are mixed, in incapsulating, medicated powder 0.4g is housed in every capsules, obtains final product.
8. the as claimed in claim 4 preparation method curing the Chinese medicine composition composition powders of the brain cancer, is characterized in that, in step (2) amount of Mel be Flos dolichoris, Herba Pellioniae repentis and Flos Caraganae Franchetianae three taste crude drug gross weight 1/3.
9. the preparation method curing the Chinese medicine composition composition powders of the brain cancer as claimed in claim 4, is characterized in that, places 7 hours in step (2).
10. the preparation method curing the Chinese medicine composition composition powders of the brain cancer as claimed in claim 4, is characterized in that, drying 15 hours in step (2).
CN201510625214.2A 2015-09-28 2015-09-28 Traditional Chinese medicine composite for treating brain cancer and preparation method thereof Withdrawn CN105168781A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1640446A (en) * 2004-01-12 2005-07-20 李加飞 Medicine for treating cancer
CN1943778A (en) * 2006-10-25 2007-04-11 薛忠 The mixture of cobra venom and Chinese medical herb extract and its application

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1640446A (en) * 2004-01-12 2005-07-20 李加飞 Medicine for treating cancer
CN1943778A (en) * 2006-10-25 2007-04-11 薛忠 The mixture of cobra venom and Chinese medical herb extract and its application

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Application publication date: 20151223