CN105412561A - Medicine for treating anhypnia - Google Patents
Medicine for treating anhypnia Download PDFInfo
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- CN105412561A CN105412561A CN201510904611.3A CN201510904611A CN105412561A CN 105412561 A CN105412561 A CN 105412561A CN 201510904611 A CN201510904611 A CN 201510904611A CN 105412561 A CN105412561 A CN 105412561A
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
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- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A61K36/185—Magnoliopsida (dicotyledons)
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Abstract
The invention aims at providing a medicine for treating anhypnia. The medicine is prepared by taking radix angelica sinensis, radix paeoniae alba, moutan bark, tangerine peel, atractylodes macrocephala koidz. (soil processed), platycladi seeds, amber, Chinese magnoliavine fruit, roses, radix glehniae, magnets, rhizoma pinellinae praeparata, massa medicata fermentata fujianensis, poria cocos, radix ophiopogonis and prepared radix licorice, mixing the components after flowing steam sterilization and drying are conducted, smashing the mixture into medicine powder of 100 meshes or above and filling capsules with the medicine powder. The medicine is free of toxic and side effects and has a good treatment effect when used for treating anhypnia.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of of insomnia patients, particularly relating to a kind of take Chinese medicine as the medicine for the treatment of of insomnia patients prepared by crude drug.
Background technology
Insomnia is often referred to patient to not meeting the length of one's sleep or quality and affecting a kind of subjective experience of social function on daytime, and its maximum effect is spiritual aspect, seriously a bit can cause schizophrenia.Insomnia comprises and waking up too early in difficulty falling asleep, often awakening or morning, the symptom such as can cause that the feeling of fatigue of people, uneasiness, general malaise, listless, delay of response, headache, memory are not concentrated.
Doctor trained in Western medicine mainly adopts sleeping class medicine to solve at present, although effect is got instant result, often takes untoward reaction such as easily producing dependency, drug resistance, withdrawal symptom.
Summary of the invention
The object of this invention is to provide a kind of medicine for the treatment of of insomnia patients, treatment of insomnia patients is had no side effect, there is good curative effect.
The medicine of a kind for the treatment of of insomnia patients of the present invention is that crude drug prepares by the Chinese medicine of following parts by weight:
Radix Angelicae Sinensis 5 ~ 15, the Radix Paeoniae Alba 5 ~ 15, Cortex Moutan 10 ~ 30, Pericarpium Citri Reticulatae 4 ~ 6,
The Rhizoma Atractylodis Macrocephalae (parching with earth) 5 ~ 15, Semen Platycladi 5 ~ 15, succinum 4 ~ 6, Fructus Schisandrae Chinensis 4 ~ 6,
Flos Rosae Rugosae 2 ~ 5, Radix Glehniae 4 ~ 6, Magnetitum 10 ~ 30, Rhizoma Pinelliae Preparatum 4 ~ 6,
Massa Medicata Fermentata 4 ~ 6, Poria 5 ~ 15, Radix Ophiopogonis 2 ~ 5, Radix Glycyrrhizae Preparata 3 ~ 5.
Preferably, medicine of the present invention is that crude drug prepares by the Chinese medicine of following parts by weight:
Radix Angelicae Sinensis 10, the Radix Paeoniae Alba 10, Cortex Moutan 20, Pericarpium Citri Reticulatae 5, the Rhizoma Atractylodis Macrocephalae (parching with earth) 10, Semen Platycladi 10, succinum 5, Fructus Schisandrae Chinensis 5, Flos Rosae Rugosae 3.5, Radix Glehniae 5, Magnetitum 20, Rhizoma Pinelliae Preparatum 5, Massa Medicata Fermentata 5, Poria 10, Radix Ophiopogonis 3.5, Radix Glycyrrhizae Preparata 4.
Said medicine can make any one peroral dosage form on pharmaceutics as tablet, pill, powder, capsule etc.The preferred capsule of the present invention.
The preparation method of capsule of the present invention: by Radix Angelicae Sinensis, the Radix Paeoniae Alba, Cortex Moutan, Pericarpium Citri Reticulatae, the Rhizoma Atractylodis Macrocephalae (parching with earth), Semen Platycladi, succinum, Fructus Schisandrae Chinensis, Flos Rosae Rugosae, Radix Glehniae, Magnetitum, Rhizoma Pinelliae Preparatum, Massa Medicata Fermentata, Poria, Radix Ophiopogonis, Radix Glycyrrhizae Preparata, according to described parts by weight through flowing steam sterilization, mixing after drying, be ground into the medicated powder of more than 100 orders, incapsulate and get final product.
The traditional Chinese medical science thinks that insomnia is that yin-Yang is unbalance, causes people's function to be in the many factors such as excited state, thus can't fall asleep.In prescription of the present invention, Radix Angelicae Sinensis is sweet, pungent, warm, return liver, the heart, spleen channel, enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, moisturize laxation, the all cards of main blood deficiency, menoxenia, amenorrhea, dysmenorrhea, for weight, ulcer sores, injury from falling down after blood deficiency dull yellowish colored skin, dizzy cardiopalmus, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, dryness of the intestine dyschezia, bloody dysentery; The Radix Paeoniae Alba is cool in nature, bitter in the mouth is sour, be slightly cold, and has the effects such as blood-supplementing blood-nourishing, suppressing liver-YANG, easing the affected liver to relieve pain, astringing YIN to stop sweating, is applicable to fever due to yin deficiency, menoxenia, the breast abdomen pain over the hypochondriac region, extremity contraction urgency, dysentery stomachache, spontaneous sweating, metrorrhagia, the inferior disease of band; Cortex Moutan is bitter, pungent, be slightly cold, and GUIXIN, liver, kidney channel, have clearing away heat and cooling blood, activating blood circulation to dissipate blood stasis, reducing the asthenic fever effect; Pericarpium Citri Reticulatae bitter in the mouth, pungent, warm in nature, return lung, spleen channel, regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm, distension and fullness in the abdomen, lack of appetite and vomiting, cough with copious phlegm; The Rhizoma Atractylodis Macrocephalae (parching with earth) bitter in the mouth, sweet, warm in nature, return spleen, stomach warp, invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive, to have loose bowels for insufficiency of the spleen lack of appetite, abdominal distention, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement; Semen Platycladi sweet in the mouth, property are flat, GUIXIN, kidney, large intestine channel, and tranquilizing by nourishing the heart, loosening bowel to relieve constipation, hidroschesis, for deficiency of YIN-blood, fidgets due to deficiency insomnia, severe palpitation, dryness of the intestine constipation, night sweat due to yin deficiency; Succinum sweet in the mouth, property are flat, can tranquilizing the mind, control malaise, insomnia and dreamful sleep and infantile convulsion epilepsy; Fructus Schisandrae Chinensis sour in the mouth, sweet, warm in nature, return lung, the heart, kidney channel, restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming, for chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous sweating, Tianjin wound is thirsty, interior-heat is quenched one's thirst, palpitation and insomnia; Flos Rosae Rugosae sweet and slightly bitter taste, warm in nature, gas is fragrant, kind can dispersing the stagnated live-QI to relieve the stagnation of QI, adjust in be amusing, can be used for incoordination between the liver and stomach, breast association distending pain, nausea and vomiting, anorexia; Radix Glehniae sweetness and bitterness is light, cool, cold nature, sweet in the mouth, micro-hardship, enter lung, spleen channel, nourishing YIN and clearing away lung-heat, reinforcing stomach reg fluid, again can nourishing the liver, thirsty for lung-heat type cough, chronic cough expectorant blood, calentura Tianjin wound; Magnetitum is salty, tremble with fear, return liver, the heart, kidney channel, tranquillizing the mind by relieving convulsion, suppressing the hyperactive liver and subsiding YANG, hearing-improing and eyesight improving, helping inspiration to relieve asthma, for insomnia of palpitating with fear, have a dizzy spell, blurring of vision, Hiccough and deaf, asthma of suffering from a deficiency of the kidney; Rhizoma Pinelliae Preparatum is pungent, warm, return spleen, stomach, lung meridian, drying dampness to eliminate phlegm, for dry laryngopharynx, abundant expectoration cough with asthma, phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, syncope due to accumulation of phlegm headache; Massa Medicata Fermentata induce sweat and in, for cold and heat headache, dyspepsia resistance in, vomiting distension; Poria sweet in the mouth, light, property are put down, GUIXIN, lung, spleen, kidney channel, promoting diuresis to eliminate damp pathogen, spleen invigorating, mind calming, have loose bowels for edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, loose stool, irritability, palpitation with fear insomnia; Radix Ophiopogonis sweet, micro-hardship, be slightly cold, GUIXIN, lung, stomach warp, YIN nourishing and the production of body fluid promoting, lung moistening clear away heart-fire, cough for dryness of the lung dry cough, deficiency of YIN consumptive disease, sore throat pharyngalgia, Tianjin wound be thirsty, interior-heat is quenched one's thirst, vexed insomnia, dryness of the intestine constipation; Radix Glycyrrhizae Preparata is sweet, put down, enter spleen, stomach warp, invigorating the spleen and replenishing QI and middle emergency, lung moistening, removing toxic substances, coordinating the actions of various ingredients in a prescription.All medicine compatibilities, have tonifying the kidney for tranquilization, spleen reinforcing nourishing the stomach, heat clearing away suppressing the hyperactive liver, effect of QI invigorating, the dirty equilibrium between yin and yang of conditioning internal organs, treatment of insomnia patients, Be very effective.
Capsule medicine of the present invention has following characteristics:
Capsule had both protected the medicine property of medicine and be not destroyed, and also protected digestive organs and respiratory tract etc.
For investigating clinical efficacy and the safety of medicine of the present invention further, the medicine capsule treatment curative effect of 120 routine insomniaies to embodiment 1, embodiment 2, embodiment 3 is selected to carry out clinical observation.
In 120 routine cases, male 62 example, women 58 example, at 23 ~ 75 years old age, is divided into three groups often to organize 40 examples at random, and three groups of cases through statistical analysis no significant difference, have comparability in age etc.
Diagnostic criteria
Formulate with reference to the efficacy assessment standard in current international practice diagnostic criteria and " new Chinese medicine guideline of clinical investigations ",
1, have the classical symptom of insomnia: difficulty falling asleep, be interrupted and sleep more, non-sleeping of seemingly sleeping, awakens often, early awakening, awake after can not sleep again; 2, above-mentioned sleep disorder at least occurs 3 times weekly, and continues more than 2 weeks, has history of attack repeatedly; 3, daytime common lassitude, dizzy feeling of fullness in the head, nervous vexed; 4, the concurrent insomnia of physical disease or other mental sickness is got rid of.
Therapeutic Method
Usage and dosage: oral, one time 5-6,2 ~ 3 times on the one.Maror is avoided at period in a medicine.
Criterion of therapeutical effect
Cure: sleep is normal, simultaneous phenomenon disappears.Take a turn for the better: the length of one's sleep extends, simultaneous phenomenon improves.Take effect: patient mental's situation and simultaneous phenomenon are improved.Invalid: symptom is without change.
After three groups of case treatments, comparitive study statistical result is as follows.
Detailed description of the invention
Embodiment 1
Get Radix Angelicae Sinensis 300 grams, the Radix Paeoniae Alba 300 grams, Cortex Moutan 600 grams, Pericarpium Citri Reticulatae 150 grams, the Rhizoma Atractylodis Macrocephalae (parching with earth) 300 grams, Semen Platycladi 300 grams, succinum 150 grams, Fructus Schisandrae Chinensis 150 grams, Flos Rosae Rugosae 105 grams, Radix Glehniae 150 grams, Magnetitum 600 grams, Rhizoma Pinelliae Preparatum 150 grams, Massa Medicata Fermentata 150 grams, 300 grams, Poria, Radix Ophiopogonis 105 grams, Radix Glycyrrhizae Preparata 120 grams, through flowing steam sterilization, mixing after drying at 35 DEG C, grinding and processing becomes the medicated powder of more than 100 orders, incapsulate, every loading amount 0.25 gram.
Embodiment 2
Get Radix Angelicae Sinensis 150 grams, the Radix Paeoniae Alba 150 grams, Cortex Moutan 300 grams, Pericarpium Citri Reticulatae 120 grams, the Rhizoma Atractylodis Macrocephalae (parching with earth) 150 grams, Semen Platycladi 150 grams, succinum 120 grams, Fructus Schisandrae Chinensis 120 grams, Flos Rosae Rugosae 60 grams, Radix Glehniae 120 grams, Magnetitum 300 grams, Rhizoma Pinelliae Preparatum 120 grams, Massa Medicata Fermentata 120 grams, 150 grams, Poria, Radix Ophiopogonis 60 grams, Radix Glycyrrhizae Preparata 90 grams.Through flowing steam sterilization, mixing after drying at 40 DEG C, grinding and processing becomes the medicated powder of more than 100 orders, incapsulates, every loading amount 0.26 gram.
Embodiment 3
Get Radix Angelicae Sinensis 450 grams, the Radix Paeoniae Alba 450 grams, Cortex Moutan 900 grams, Pericarpium Citri Reticulatae 180 grams, the Rhizoma Atractylodis Macrocephalae (parching with earth) 450 grams, Semen Platycladi 450 grams, succinum 180 grams, Fructus Schisandrae Chinensis 180 grams, Flos Rosae Rugosae 140 grams, Radix Glehniae 180 grams, Magnetitum 900 grams, Rhizoma Pinelliae Preparatum 180 grams, Massa Medicata Fermentata 180 grams, 450 grams, Poria, Radix Ophiopogonis 150 grams, Radix Glycyrrhizae Preparata 150 grams.Through flowing steam sterilization, mixing after drying at 50 DEG C, grinding and processing becomes the medicated powder of more than 100 orders, incapsulates, every loading amount 0.27 gram.
Claims (3)
1. a medicine for treatment of insomnia patients is that crude drug prepares by the Chinese medicine of following parts by weight:
Radix Angelicae Sinensis 5 ~ 15, the Radix Paeoniae Alba 5 ~ 15, Cortex Moutan 10 ~ 30, Pericarpium Citri Reticulatae 4 ~ 6,
The Rhizoma Atractylodis Macrocephalae (parching with earth) 5 ~ 15, Semen Platycladi 5 ~ 15, succinum 4 ~ 6, Fructus Schisandrae Chinensis 4 ~ 6,
Flos Rosae Rugosae 2 ~ 5, Radix Glehniae 4 ~ 6, Magnetitum 10 ~ 30, Rhizoma Pinelliae Preparatum 4 ~ 6,
Massa Medicata Fermentata 4 ~ 6, Poria 5 ~ 15, Radix Ophiopogonis 2 ~ 5, Radix Glycyrrhizae Preparata 3 ~ 5.
2. the medicine for the treatment of of insomnia patients according to claim 1, is characterized in that, is be that crude drug prepares by the Chinese medicine of following parts by weight:
Radix Angelicae Sinensis 10, the Radix Paeoniae Alba 10, Cortex Moutan 20, Pericarpium Citri Reticulatae 5, the Rhizoma Atractylodis Macrocephalae (parching with earth) 10, Semen Platycladi 10, succinum 5, Fructus Schisandrae Chinensis 5, Flos Rosae Rugosae 3.5, Radix Glehniae 5, Magnetitum 20, Rhizoma Pinelliae Preparatum 5, Massa Medicata Fermentata 5, Poria 10, Radix Ophiopogonis 3.5, Radix Glycyrrhizae Preparata 4.
3. the preparation method of the medicine for the treatment of of insomnia patients according to claim 1 is, by Radix Angelicae Sinensis, the Radix Paeoniae Alba, Cortex Moutan, Pericarpium Citri Reticulatae, the Rhizoma Atractylodis Macrocephalae (parching with earth), Semen Platycladi, succinum, Fructus Schisandrae Chinensis, Flos Rosae Rugosae, Radix Glehniae, Magnetitum, Rhizoma Pinelliae Preparatum, Massa Medicata Fermentata, Poria, Radix Ophiopogonis, Radix Glycyrrhizae Preparata, according to described parts by weight through flowing steam sterilization, mixing after drying, be ground into the medicated powder of more than 100 orders, incapsulate and get final product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510904611.3A CN105412561A (en) | 2015-12-09 | 2015-12-09 | Medicine for treating anhypnia |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510904611.3A CN105412561A (en) | 2015-12-09 | 2015-12-09 | Medicine for treating anhypnia |
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| CN105412561A true CN105412561A (en) | 2016-03-23 |
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| CN201510904611.3A Pending CN105412561A (en) | 2015-12-09 | 2015-12-09 | Medicine for treating anhypnia |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112294913A (en) * | 2020-09-30 | 2021-02-02 | 仁和堂药业有限公司 | Medicine for treating insomnia and preparation process thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103800654A (en) * | 2013-12-10 | 2014-05-21 | 济南新起点医药科技有限公司 | Traditional Chinese medicinal composition for treating insomnia due to liver depression of fire |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103800654A (en) * | 2013-12-10 | 2014-05-21 | 济南新起点医药科技有限公司 | Traditional Chinese medicinal composition for treating insomnia due to liver depression of fire |
Non-Patent Citations (2)
| Title |
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| 于晨媛: "解郁安神汤治疗顽固性失眠48例", 《陕西中医》 * |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112294913A (en) * | 2020-09-30 | 2021-02-02 | 仁和堂药业有限公司 | Medicine for treating insomnia and preparation process thereof |
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