CN104784646A

CN104784646A - Pharmaceutical composition for treating infantile hernia and preparation method of pharmaceutical composition

Info

Publication number: CN104784646A
Application number: CN201510234690.1A
Authority: CN
Inventors: 秦永春; 朱甲峰; 匡立山; 郭延举; 肖龙明; 程绪鹏
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-05-11
Filing date: 2015-05-11
Publication date: 2015-07-22

Abstract

The invention discloses a pharmaceutical composition for treating infantile hernia and a preparation method of the pharmaceutical composition. The pharmaceutical composition is prepared from the following raw herbal materials: sheathed monkshood root, akebiaquinata, achyranthes aspera, sargentgloryvine stem, rhizoma sparganii, berchemia lineate, ligusticum wallichii, calamus, pumice, fructus persicae immaturus, air potato, natural copper, parmelia tinctourium, pinellia ternate, mangnolia officinalis, sword bean, semen brassicae, rhizoma cyperi, curcuma zedoary, sensitive plant, angelica citriodora hance, oblongleaf kadsura stem root, root or leaf of cochinchina raspberry, rhizoma nardostachyos, ivy, semen raphani, betel nut, procumbent speedwell, campsis grandiflora, brucea javanica, dutchmanspipe root and indian kalimeris herb. The pharmaceutical composition has the beneficial effects of promoting blood circulation to remove blood stasis, eliminating goiter and removing stasis, promoting qi circulation to relieve pain, opening depression, and guiding qi downward, is mainly used for promoting infantile hernia to heal, and has the advantages of quick effect-taking, high effective rate, exact curative effect, short course of treatment, no toxic or side effect, low price, and the like.

Description

A kind of pharmaceutical composition for the treatment of infantile hernia and preparation method thereof

Technical field

The present invention relates to technical field of medicine, particularly a kind of pharmaceutical composition for the treatment of infantile hernia and preparation method thereof.

Background technology

Infantile hernia and children inguinal hernia gas, be commonly called as hernia, is modal disease in children's's common surgical procedures, at embryonic stage, there is one " peritoneum processus vaginalis " at groin place, and testis can be helped to fall into the fixing of scrotum or round ligament of uterus, after some child birth, this processus vaginalis is closed not exclusively, causes Intraabdominal small intestinal, nethike embrane, ovary, fallopian tube etc. enter this processus vaginalis, namely become hernia, if only there is peritoneal fluid to enter in scrotum, be edema of scrotum.The general incidence rate of hernia is 1-4%, and boy student is 10 times of schoolgirl, and premature infant is then higher, and may betide both sides.

First children inguinal hernia gas affect the digestive system of patient, thus occur that hypogastric region falling inflation, abdominal distention gas, stomachache, constipation, absorption function are poor, degradation symptom under fatiguability and body constitution.Again because pars inguinalis is adjacent with genitourinary system, the normal development of reproductive system can be affected because of the extruding of hernia.Also because the intestinal tube in hernical sac or omentum majus are vulnerable to extruding or collision causes inflammatory swelling, cause hernia reduction difficulty, cause hernia incarceration, the severe complication such as cause that an awful ache in the belly and intestinal obstruction, intestinal tube be downright bad, also process likely threat to life not in time.

The symptom of infantile hernia: 1. infantile hernia likely can occur after a couple of days, several months or several years after birth.2. usually cry and scream child, strenuous exercise, constipation with dry stool time, have the swollen thing of a projection bulk at groin place, extend to scrotum or labial regions sometimes; Can die away when lying low or press with hands.3. once hernia block generation incarceration (hernia enclosed mass cannot Hui Na), there will be stomachache, Nausea and vomiting, fever, anorexia or cry and scream, dysphoria.4. infantile hernia their early stage, the thing that swells when the flat sleeping peace and quiet of child can disappear; Along with intraabdominal pressure continue increase, swollen thing can drop in scrotum.If at this moment can remove the factor that intra-abdominal pressure increases, and make infant flat sleeping, or the thing that will swell lightly pushes toward direction, abdominal cavity, swollen thing then turns back to abdominal cavity by that passage during testicular descent, and swollen thing disappears, and this situation is called recoverability hernia.5. if swollen thing can not return and receive abdominal cavity, just there will be stomachache aggravation, crying and screaming more than, then occur the ileus symptoms such as vomiting, abdominal distention, defecation be not smooth, visible oval swollen body thing in groin or scrotum, quality is hard, touches a tender spot obvious; Incarceration person of long duration skin is red and swollen as seen, receives, likely occur the severe complications such as intestinal tube ischemic necrosis if long-time intestinal tube can not return.

The cause of disease of infantile hernia: because the testis of boy is in utero just being down to scrotum by inguinal canal, the peritoneum thereupon moved down then forms processus vaginalis.If processus vaginalis does not also have locking after baby due, or inadequacy, become larger lacuna on the contrary, intraperitoneal is tolerant from dashing forward to body surface, and will form hernia here.Again because slightly late on the left of right testicle suppression ratio, processus vaginalis locking is also comparatively slow, therefore right side inguinal hernia is more.Certainly, girl also can form hernia because of stomach wall weakness, and just sickness rate is relatively lower.

The inspection of infantile hernia: inguinal hernia is apt to occur in one-year-old following child, if during outbreak, have the lump heaved at groin, slightly vigilance is just very easy to find.If child has following performance to attract great attention.1. unknown cause cry and scream incessantly need consider suffer from infantile hernia and with incarceration may; 2. violent vomiting, fever; Need consider suffer from infantile hernia and with incarceration may; 3. intestinal obstruction; Need consider suffer from infantile hernia and with incarceration may; 4. find hemafecia; Need consider suffer from infantile hernia and with incarceration may.Must carefully detect with or without inguinal hernia.

The differential diagnostic method of infantile hernia: 1. child's unknown cause cry and scream more than, then suffer from infantile hernia and probability with incarceration is large.2. there is violent vomiting in child, adstante febre, then suffer from infantile hernia and probability with incarceration is large.3. sometimes there is intestinal obstruction phenomenon; Then suffer from infantile hernia and probability with incarceration is large.4. when if hemafecia appears in child, then child suffers from infantile hernia and probability with incarceration is large.

The prevention of infantile hernia: 1, because hernia can occur at infancy stage, therefore should often note in this period pars inguinalis or the scrotum place of observing child, whether swell, or whether there is flickering block thing, meet query and consult a physician in time.Although 2 herniates mostly comparatively be boy, also can there is hernia in girl.More to enhance your vigilance to the hernia of girl because often have ovary, fallopian tube enters hernical sac.3, the abdominal part of child is not wrapped up in too tight by infancy stage, in order to avoid increase the weight of intraabdominal pressure.Do not allow too early the standing of child, in order to avoid intestinal tube tenesmus forms inguinal hernia.4, the food that easy to digest and cellulose is many is a bit eaten, to keep free movement of the bowels.When child is hard and dry, relieving constipation measure should be taked, not allow child firmly defecate.5, do not allow child cough loudly, the children's suffering from cough will suitably eat a little antitussive under physician guidance.Avoid child to cry loudly, prevent abdominal pressure from raising.

At present, because Western medicine effectively cannot treat infantile hernia, and easily recur, and have a lot of side effect, therefore, there is very large demand to the medicine of effectively treating infantile hernia in people.

Summary of the invention

Technical problem to be solved by this invention is, a kind of pharmaceutical composition for the treatment of infantile hernia and preparation method thereof is provided, the present invention has blood circulation promoting and blood stasis dispelling, effect of the wart that disappears eliminating stagnation and promoting the circulation of QI to relieve pain, have dissipating depression of QI concurrently, pleasant effect, be mainly used in promoting infantile hernia postoperation recovery, have rapid-action, effective percentage is high, determined curative effect, treatment short treating period, have no side effect and the advantage such as price is low.

In order to solve the problems of the technologies described above, the invention provides a kind of pharmaceutical composition for the treatment of infantile hernia, wherein, following raw medicinal material is comprised: comprise following raw medicinal material: Radix Aconiti Vaginati, Caulis Akebiae, Radix Achyranthis, Caulis Sargentodoxae, Rhizoma Sparganii, Radix berchemiae lineatae, Rhizoma Chuanxiong, Rhizoma Acori Calami, Pumex, Fructus Pruni persicae immaturus, Rhizoma Dioscoreae Bulbiferae, Pyritum, Parmelia saxatilis Ach., the Rhizoma Pinelliae, Cortex Magnoliae Officinalis, Semen Canavaliae, Semen Sinapis Albae, Rhizoma Cyperi, Rhizoma Curcumae, Herba Mimosae Pudicae, Radix osterici citriodori (Radix Angelicae Citriodorae), Caulis Seu Radix Kadsurae Oblongifoliae, Radix seu Folium Rubi Cochinchinensis, Radix Et Rhizoma Nardostachyos, Caulis Hederae Sinensis, Semen Raphani and Semen Arecae.

In described pharmaceutical composition, the ratio of weight and number of each raw medicinal material is: Radix Aconiti Vaginati 15-35 part, Caulis Akebiae 10-20 part, Radix Achyranthis 14-32 part, Caulis Sargentodoxae 18-37 part, Rhizoma Sparganii 13-27 part, Radix berchemiae lineatae 15-40 part, Rhizoma Chuanxiong 11-31 part, Rhizoma Acori Calami 15-25 part, Pumex 13-32 part, Fructus Pruni persicae immaturus 2-3 part, Rhizoma Dioscoreae Bulbiferae 12-22 part, Pyritum 14-36 part, Parmelia saxatilis Ach. 11-21 part, Rhizoma Pinelliae 2-3 part, Cortex Magnoliae Officinalis 16-38 part, Semen Canavaliae 18-42 part, Semen Sinapis Albae 13-33 part, Rhizoma Cyperi 14-28 part, Rhizoma Curcumae 10-30 part, Herba Mimosae Pudicae 3-5 part, Radix osterici citriodori (Radix Angelicae Citriodorae) 12-24 part, Caulis Seu Radix Kadsurae Oblongifoliae 17-36 part, Radix seu Folium Rubi Cochinchinensis 15-25 part, Radix Et Rhizoma Nardostachyos 11-33 part, Caulis Hederae Sinensis 16-28 part, Semen Raphani 11-31 part and Semen Arecae 14-24 part.

In described pharmaceutical composition, the ratio of weight and number of each raw medicinal material is: Radix Aconiti Vaginati 24 parts, Caulis Akebiae 15 parts, Radix Achyranthis 32 parts, Caulis Sargentodoxae 20 parts, Rhizoma Sparganii 17 parts, Radix berchemiae lineatae 35 parts, Rhizoma Chuanxiong 23 parts, Rhizoma Acori Calami 20 parts, Pumex 28 parts, Fructus Pruni persicae immaturus 2 parts, Rhizoma Dioscoreae Bulbiferae 22 parts, Pyritum 34 parts, Parmelia saxatilis Ach. 21 parts, the Rhizoma Pinelliae 2 parts, Cortex Magnoliae Officinalis 38 parts, Semen Canavaliae 40 parts, Semen Sinapis Albae 33 parts, Rhizoma Cyperi 21 parts, Rhizoma Curcumae 18 parts, Herba Mimosae Pudicae 3 parts, Radix osterici citriodori (Radix Angelicae Citriodorae) 22 parts, Caulis Seu Radix Kadsurae Oblongifoliae 30 parts, Radix seu Folium Rubi Cochinchinensis 20 parts, Radix Et Rhizoma Nardostachyos 33 parts, Caulis Hederae Sinensis 25 parts, Semen Raphani 31 parts and Semen Arecae 24 parts.

In described pharmaceutical composition, the ratio of weight and number of each raw medicinal material is: Radix Aconiti Vaginati 33 parts, Caulis Akebiae 20 parts, Radix Achyranthis 24 parts, Caulis Sargentodoxae 35 parts, Rhizoma Sparganii 24 parts, Radix berchemiae lineatae 25 parts, Rhizoma Chuanxiong 30 parts, Rhizoma Acori Calami 17 parts, Pumex 32 parts, Fructus Pruni persicae immaturus 2 parts, Rhizoma Dioscoreae Bulbiferae 14 parts, Pyritum 26 parts, Parmelia saxatilis Ach. 18 parts, the Rhizoma Pinelliae 3 parts, Cortex Magnoliae Officinalis 26 parts, Semen Canavaliae 35 parts, Semen Sinapis Albae 25 parts, Rhizoma Cyperi 18 parts, Rhizoma Curcumae 30 parts, Herba Mimosae Pudicae 3 parts, Radix osterici citriodori (Radix Angelicae Citriodorae) 12 parts, Caulis Seu Radix Kadsurae Oblongifoliae 36 parts, Radix seu Folium Rubi Cochinchinensis 25 parts, Radix Et Rhizoma Nardostachyos 11 parts, Caulis Hederae Sinensis 20 parts, Semen Raphani 31 parts and Semen Arecae 16 parts.

Described pharmaceutical composition also comprises: Herba veronicae, Flos Campsis, Fructus Bruceae, Radix Aristolochiae and Herba Kalimeridis.

In described pharmaceutical composition, the ratio of weight and number of each raw medicinal material is: Radix Aconiti Vaginati 15-35 part, Caulis Akebiae 10-20 part, Radix Achyranthis 14-32 part, Caulis Sargentodoxae 18-37 part, Rhizoma Sparganii 13-27 part, Radix berchemiae lineatae 15-40 part, Rhizoma Chuanxiong 11-31 part, Rhizoma Acori Calami 15-25 part, Pumex 13-32 part, Fructus Pruni persicae immaturus 2-3 part, Rhizoma Dioscoreae Bulbiferae 12-22 part, Pyritum 14-36 part, Parmelia saxatilis Ach. 11-21 part, Rhizoma Pinelliae 2-3 part, Cortex Magnoliae Officinalis 16-38 part, Semen Canavaliae 18-42 part, Semen Sinapis Albae 13-33 part, Rhizoma Cyperi 14-28 part, Rhizoma Curcumae 10-30 part, Herba Mimosae Pudicae 3 parts, Radix osterici citriodori (Radix Angelicae Citriodorae) 12-24 part, Caulis Seu Radix Kadsurae Oblongifoliae 17-36 part, Radix seu Folium Rubi Cochinchinensis 15-25 part, Radix Et Rhizoma Nardostachyos 11-33 part, Caulis Hederae Sinensis 16-28 part, Semen Raphani 11-31 part, Semen Arecae 14-24 part, Herba veronicae 13-35 part, Flos Campsis 10-20 part, Fructus Bruceae 3-5 part, Radix Aristolochiae 1-2 part and Herba Kalimeridis 15-38 part.

In described pharmaceutical composition, the ratio of weight and number of each raw medicinal material is: Radix Aconiti Vaginati 20 parts, Caulis Akebiae 15 parts, Radix Achyranthis 32 parts, Caulis Sargentodoxae 28 parts, Rhizoma Sparganii 24 parts, Radix berchemiae lineatae 40 parts, Rhizoma Chuanxiong 31 parts, Rhizoma Acori Calami 16 parts, Pumex 32 parts, Fructus Pruni persicae immaturus 2 parts, Rhizoma Dioscoreae Bulbiferae 21 parts, Pyritum 36 parts, Parmelia saxatilis Ach. 14 parts, the Rhizoma Pinelliae 2 parts, Cortex Magnoliae Officinalis 38 parts, Semen Canavaliae 42 parts, Semen Sinapis Albae 33 parts, Rhizoma Cyperi 28 parts, Rhizoma Curcumae 16 parts, Herba Mimosae Pudicae 3 parts, Radix osterici citriodori (Radix Angelicae Citriodorae) 22 parts, Caulis Seu Radix Kadsurae Oblongifoliae 36 parts, Radix seu Folium Rubi Cochinchinensis 25 parts, Radix Et Rhizoma Nardostachyos 33 parts, Caulis Hederae Sinensis 22 parts, Semen Raphani 30 parts, Semen Arecae 20 parts, Herba veronicae 35 parts, Flos Campsis 12 parts, Fructus Bruceae 3 parts, Radix Aristolochiae 2 parts and Herba Kalimeridis 38 parts.

When the dosage form of described pharmaceutical composition is honey refining pill, its preparation method comprises the following steps:

The first step, by grind into powder after the Rhizoma Pinelliae, Cortex Magnoliae Officinalis, Semen Canavaliae, Semen Sinapis Albae, Rhizoma Cyperi, Rhizoma Curcumae, Herba Mimosae Pudicae, Radix osterici citriodori (Radix Angelicae Citriodorae) distillation crystallization;

Second step, again surplus stock medical material is mixed in proportion, add relative to 70-95% soak with ethanol 0.5-1.5 hour of mixture 3-5 times amount, heating extraction 1-2 time, each 0.5-1.0 hour, filter to obtain extracting solution, medicinal residues are for subsequent use, merge extractive liquid, be the ultrafiltration post ultrafiltration of 38000-84000 again through the molecular weight that dams, ultrafiltration decompression removing ethanol, during simmer down to 85-92 DEG C, relative density is the extractum of 1.03, becomes component 1;

Medicinal residues obtained above are added 2-3 times amount water soaking 1.0-2.0 hour by the 3rd step, within 1.0-1.5 hour, extract 1 time, are the extractum of 1.1, as component 2 by relative density during extracting solution heating under reduced pressure simmer down to 80-90 DEG C;

4th step, mixes component 1, component 2 with the powder that the first step obtains, adds and is twisted into honey refining pill relative to the Mel of mixture 2 times amount.

When the dosage form of described pharmaceutical composition is capsule, its preparation method comprises the following steps:

The first step, is mixed in proportion each for described Chinese medicine raw medicinal material, and adding relative to the determining alcohol of mixture quality 2 ~ 4 times is the ethanol of 85 ~ 95%, reflux 1 ~ 3 hour, extracts, and filters acquisition first extracting solution; It is the ethanol of 85 ~ 95% that the medicinal residues that filtration obtains add relative to the determining alcohol of described medicinal residues quality 1 ~ 2 times again, reflux 1 ~ 3 hour, extracts, and filters acquisition second extracting solution; First extracting solution and the second extracting solution are merged, concentrating under reduced pressure removing alcohol solvent, dry, obtain and get dry extract;

Second step, is placed on the dry cream that the first step obtains in super micron mill and pulverizes 1 ~ 2 hour, pulverize, sieve, obtain 300 order ~ 400 object micropowders;

3rd step, adds Pulvis Talci, magnesium stearate successively in the micropowders that second step obtains, and carries out mixing process, obtains capsule 's content; Described micropowders, magnesium stearate and talcous weight ratio are 100: 0.15 ~ 0.5:0.15 ~ 0.5, incapsulate in housing by described capsule 's content, obtain capsule finished product.

When the dosage form of described medicine is decoction, its preparation method comprises the following steps:

The first step: purple casserole is put in described raw medicinal material mixing, adds clear water, to clear water dipped medical material upper surface 2-5cm, soak 3-10 hour;

Second step: purple casserole is placed on fire, after intense fire boils, using slow fire instead, to decoct the 30-50 minute dosage to medicinal liquid be slowly 100-300ml, filters, obtain filtrate a, for subsequent use;

3rd step: residue medicinal residues are added clear water again, to clear water dipped medical material upper surface 2-3cm, soaks 3-10 hour;

4th step: be placed in by purple casserole on fire, after intense fire boils, using slow fire instead, to decoct the 25-35 minute dosage to medicinal liquid be slowly 100-300ml, filters, obtain filtrate b, mixed and obtain decoction by filtrate a and filtrate b.

The invention has the beneficial effects as follows: the present invention has blood circulation promoting and blood stasis dispelling, effect of the wart that disappears eliminating stagnation and promoting the circulation of QI to relieve pain, have dissipating depression of QI concurrently, pleasant effect, be mainly used in promoting infantile hernia postoperation recovery, have rapid-action, effective percentage is high, determined curative effect, treatment short treating period, have no side effect and the advantage such as price is low.

Detailed description of the invention

The present invention with blood circulation promoting and blood stasis dispelling, the wart that disappears eliminating stagnation and promoting the circulation of QI to relieve pain for primary treatment principle, treatment infantile hernia, wherein, following raw medicinal material is comprised: Radix Aconiti Vaginati, Caulis Akebiae, Radix Achyranthis, Caulis Sargentodoxae, Rhizoma Sparganii, Radix berchemiae lineatae, Rhizoma Chuanxiong, Rhizoma Acori Calami, Pumex, Fructus Pruni persicae immaturus, Rhizoma Dioscoreae Bulbiferae, Pyritum, Parmelia saxatilis Ach., the Rhizoma Pinelliae, Cortex Magnoliae Officinalis, Semen Canavaliae, Semen Sinapis Albae, Rhizoma Cyperi, Rhizoma Curcumae, Herba Mimosae Pudicae, Radix osterici citriodori (Radix Angelicae Citriodorae), Caulis Seu Radix Kadsurae Oblongifoliae, Radix seu Folium Rubi Cochinchinensis, Radix Et Rhizoma Nardostachyos, Caulis Hederae Sinensis, Semen Raphani, Semen Arecae, Herba veronicae, Flos Campsis, Fructus Bruceae, Radix Aristolochiae and Herba Kalimeridis.

Wherein, the pharmacology of above-mentioned raw materials medical material is as follows:

Fructus Pruni persicae immaturus: source: " decoction pieces is newly joined ".Source: be the immature fruit of rosaceous plant Fructus Persicae or Prunus davidiana.4 ~ June gathers.Win green fruit, dry.The ground such as main product Jiangsu, Zhejiang, Anhui.Nature and flavor: bitter are flat." herbal classic ": " tepor." " not Lu ": " bitter in the mouth." " detailed outline ": " is bitter, and tepor is slightly poisonous." " decoction pieces is newly joined ": " sweet acid, flat." " Traditional Chinese Medicine in Sichuan will ": " property is put down, and lightly seasoned hardship is nontoxic." return through: " book on Chinese herbal medicine converge with speech ": " meridian of Foot-JUE YIN of starting with." cure mainly: control night sweat, seminal emission, spit blood, malaria, cardiac and abdominal pain; Gestation hemorrhage." classifying herbal ": " control bladder hernia, send essence, woman in menstrual period is inaccessible."

Herba veronicae: source: herbal for Relief of Famines.Nature and flavor: sweet are cool.1. herbal for Relief of Famines: " taste is sweet." 2. " Traditional Chinese Medicine in Sichuan will ": " is cool in nature, lightly seasoned, nontoxic." cure mainly: control hernia, lumbago, leucorrhea.1. " BAICAO mirror ": " control hernia, lumbago." 2. " conventional glossary of Herbs and Drugs among the people ": " reinforces the kidney, and emesis blood, controls children's's bladder hernia."

Semen Canavaliae: source: herbal for Relief of Famines.Nature and flavor: sweet, temperature.1. " detailed outline ": " sweet, flat, nontoxic." 2. " Bencao Congxin ": " is sweet, temperature." return through: " book on Chinese herbal medicine brief points ": " starts with, Foot yangming Channel." cure mainly: warming the middle warmer and descending qi, kidney tonifying complement.Control deficiency and coldness singultus, vomiting, abdominal distention, lumbago due to renal deficiency, phlegm dyspnea.1. " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " spleen invigorating." 2. " detailed outline ": " warming the middle warmer and descending qi, sharp the intestines and stomach, only singultus, kidney tonifying complement." 3. " Chinese crude drug handbook ": " the kidney invigorating, cold expelling, the therapeutic method to keep the adverse QI flowing downwards, sharp the intestines and stomach, anti-nausea.Control kidney qi deficient, the intestines and stomach is got along well, vomiting, abdominal distention, vomits and diarrhoea." 4. " Traditional Chinese Medicine in Sichuan will ": " controls thoracic fullness and stomachache, treats kidney qi and does not return unit and dysentery." control infantile hernia: Sword Jackbean Seed levigation, each money half, boiled water is taken after mixing it with water.(" Hunan medicine will ").

Rhizoma Acori Calami: source: " not Lu ".Nature and flavor: toil, temperature.1. " not Lu ": " sweet in the mouth is nontoxic." 2. " Shanghai Chinese herbal medicine handbook ": " toil, temperature." cure mainly: reduce phlegm, have one's ideas straightened out, spleen invigorating, dampness removing.Control epilepsy, palpitate with fear forgetful, mind is not asked, and humidity hysteresis painful abdominal mass is swollen, dysentery, rheumatalgia, carbuncle scabies.1. " not Lu ": " staple food parasites." 2. TAO Hong-Jing: " main air cough caused by pathogenic damp is inverse, debug, disconnected flea louse." 3. " Bencao Tujing ": " smashes end, and oil is adjusted and is coated with scabies scabies." 4. " south of the Five Ridges gather medicinal herbs record ": " stomach invigorating dehumidifying, decocts washing mange." 5. " Guizhou side among the people medicine collection ": " is aid digestion, and removing food stagnancy is eaten, and only stomachache, controls dysentery, again dispelling the wind and dampness pathogens pain." 6. " will planted by northeast medicine ": " falls apart carbuncle." 7. " Chinese herbal medicine is commonly used in Shanghai ": " tranquillizing and allaying excitement, reduces phlegm, stomach invigorating.Control epilepsy, tinnitus, be thick of hearing, breast abdominal distention is vexed." 8. " Jilin Chinese herbal medicine ": " awakening consciousness, and in ward off turbid.Training the mind dusk, tinnitus, forgetful, humidity hysteresis vent plug.Control infantile hernia, the swelling and hanging down of either of the testes, pudendum eczema: Rhizoma Acori Graminei decocts water, washes affected part.(" Jilin Chinese herbal medicine ").

Herba Mimosae Pudicae: source: " south of the Five Ridges gather medicinal herbs record ".Source: be the herb of leguminous plant Herba Mimosae Pudicae.Summer gathers, and dries.Nature and flavor: sweet, cold, poisonous.1. " the SHENGCAO property of medicine is standby to be wanted ": " sweet in the mouth, cold in nature." 2. " Nanning City's medicine will ": " is sweet, cold, slightly poisonous." 3. " practical Chinese herbal medicine ": " cold nature, mildly bitter flavor." cure mainly: heat clearing away, calm the nerves, removing food stagnancy, removing toxic substances.Control enteritis, gastritis, insomnia, infantile malnutrition, order heat swells and ache, deep abscess, herpes zoster.1. " the SHENGCAO property of medicine is standby to be wanted ": " alleviating pain and detumescence." 2. " book on Chinese herbal medicine asks former ": " applies skin ulcer, and " 3. " south of the Five Ridges gather medicinal herbs record ": " is controlled to eye covetously and had a pain." 4. " Nanning City's medicine will ": " clearing away liver-fire, control infantile malnutrition, liver-fire rising, external treatment skin infection is had a pain." 5. Guangzhou army " conventional Chinese herbal medicine handbook ": " calmness of calming the nerves." 6. " practical Chinese herbal medicine ": " clearing away heat-damp and promoting diuresis.Control deep abscess, enteritis, gastritis, hernia, infantile malnutrition."

Herba Kalimeridis: source: supplement to the Herbal.Nature and flavor: pungent are cool.1. " praise and help book on Chinese herbal medicine ": be " pungent, flat, nontoxic." 2. " beautiful Chinese catalpa medicine solution ": " bitter in the mouth is pungent, and gas is put down." 3. " occupying diet spectrum with breath ": " Gan Xin is cool." return through: 1. " detailed outline ": " enters positive bright blood system." 2. " jade seizes medicine solution ": " start with lunar lung, liver channel of foot-Jueyin." cure mainly: removing heat from blood, heat clearing away, dampness removing, removing toxic substances.Control haematemesis, epistaxis, dysentery, wound hemorrhage, malaria, jaundice, edema, stranguria with turbid discharge, pharyngalgia, sore throat, hemorrhoid, carbuncle, erysipelas, venom.1. " Japan hanako materia medica ": " root, leaf, broken stagnated blood, supports fresh blood, only epistaxis, spits blood, alloy skin ulcer, and disconnected dysentery, separates alcoholic jaundice and all bacteriums; Life is smash deposited Serpentis and is stung." 2. " detailed outline ": " root, leaf, main all malarias and spasm and pain in the abdomen, hemorrhoid." 3. " herbal classic is met former ": " controls married woman's stranguria with turbid discharge, anal fistula." 4. " medical center bun is wanted ": " the kidney invigorating life, eliminating cold-damp, warm uterus, parasite killing.Control infantile malnutrition." 5. " interrogating book on Chinese herbal medicine ": " is smash juice and is coated with impetigo and innominate toxic swelling." " smashes even with leaf with winter honey, applies positive disease innominate toxic swelling, and the person that do not burst can fall apart." 6. " Fujian traditional herbal medicine ": " stasis of blood hemostasis alive, eliminating carbuncle, removing toxic substances." 7. " Traditional Chinese Medicine in Sichuan will ": " helps digestion long-pending glutted and breast knot flatulence, and except damp and hot, diuresis, brings down a fever, and cough-relieving is coughed, removing toxic substances, treating snakebite." 8. " Yunnan Chinese herbal medicine ": " root: expelling wind and cold, relieving cough and asthma.Control bronchitis, bronchial asthma, rheumatic arthralgia, infantile hernia." 9. " register planted by Guangxi medicine ": " clearing away heat and expelling pathogen in the exterior.Control affection due to external wind and heat."

Semen Arecae: another name: bulky jade, Bin Men, blue or green son, state horse, Bing Nan, sharp Bin, Cor Gigeriae Galli Semen Arecae.Source: this product is the dry mature seed of babassu Semen Arecae Areca catechu L..Gather at the beginning of spring Mo to autumn mature fruit, after decocting in water, dry, removing peel, takes out seed, dry.Nature and flavor: bitter, pungent, temperature.Gui Jing: return stomach, large intestine channel.Cure mainly: killing insect and eliminating accumulation, sending down the abnormal ascending QI, row water, preventing the attack (or recurrence) of malaria.For cestode, ascarid, fasciolopsiasis buski, abdominal pain due to worm stagnation, stagnant dysentery, tenesmus, edema beriberi, malaria.

Semen Raphani: source: " Amplification on Materia Medica addendum ".Nature and flavor: Xin Gan are flat.1. " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " warm in nature, acrid in the mouth." 2. " detailed outline ": " Xin Gan is flat, nontoxic." 3. " beautiful Chinese catalpa medicine solution ": " is pungent, heat." 4. " Records of Tradition Chinese and Western Medicine in Combination ": " life taste is micro-pungent, temper; Fry with warm in nature." return through: enter lung, stomach warp.1. " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " enter spleen, lung two warp." 2. " medicineization justice ": " enters spleen, stomach two warp." 3. " book on Chinese herbal medicine is new again ": " enters liver, lung two warp." cure mainly: therapeutic method to keep the adverse QI flowing downwards Dingchuan, eliminates indigestion and phlegm.Control cough phlegm dyspnea, stagnation of QI due to dyspepsia, abdominal distention uncomfortable in chest, heavy after dysentery.1. " Japan hanako materia medica ": " water grinds clothes, tells wind-phlegm: vinegar grinds detumescence poison." 2. " daily book on Chinese herbal medicine ": " subcutaneous ulcer of harnessing the Yellow River and skin icteric sclera are as gold, and little hydro-thermal is red." 3. " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " therapeutic method to keep the adverse QI flowing downwards alleviating distention in middle-JIAO, disappear expansion, falls expectorant, surely shouts and breathe heavily, and attacks the intestines and stomach and stagnate, and controls mass in the abdomen, single abdomen pain." 4. " detailed outline ": " therapeutic method to keep the adverse QI flowing downwards Dingchuan, controls expectorant, helps digestion, de-swelling, sharp defecation, only pain due to disorder of QI, heavy after dysentery, sends out skin ulcer rash." 5. " medical center bun is wanted ": " raw use, tells wind-phlegm, the chest stuffiness relieving diaphragm, holder skin ulcer rash; Hot use, therapeutic method to keep the adverse QI flowing downwards expectorant, assaults fortified position long-pending, heavy after treating." 6. " book on Chinese herbal medicine is new again ": " reduces phlegm except wind, loose evil diaphoresis." 7. " occupying diet spectrum with breath ": " is controlled phlegmatic cough ， Snore and is breathed heavily, and tympanites, wind syndrome of head, drowns and close, and wrongly take tonic."

Caulis Hederae Sinensis: source: supplement to the Herbal.Nature and flavor: bitter, cool.1. supplement to the Herbal: " bitter." 2. " book on Chinese herbal medicine is new again ": " bitter in the mouth, cold nature is nontoxic." 3. " Chinese herbal medicine is commonly used in Tibet ": " property is put down, sweet in the mouth." return through: " book on Chinese herbal medicine is new again ": " enters liver, spleen two warp."

Cure mainly: dispel the wind, dampness removing, suppressing the hyperactive liver, removing toxic substances.Treating rheumatic arthritis, hepatitis, dizzy, facial hemiparalysis, epistaxis, corneal nebula, swollen ulcer drug.1. " detailed outline ": " main air wets multiple abscess pain and swollen ulcer drug." 2. " book on Chinese herbal medicine is new again ": " treating the liver is strongly fragrant, spleen reinforcing dampness removing, removes the sliding expectorant of wind, current meridians, promoting the circulation of blood and blood, and can regulate the flow of vital energy." 3. " vegetation is side just ": " controls children's's intermittent infantile convulsion, wind-phlegm.Except knife injury dog stings poison." 4. " classifying herbal ": " controls bones and muscles pain, rheumatic numbness, clothes of steeping in wine.Sore can be washed." 5. " Kaibao Bencao ": " suppressing the hyperactive liver is pleasant, and improving eyesight, controls dizziness."

Radix Et Rhizoma Nardostachyos: source: come from " detailed outline ".Another name: Gan Xiangsong, fragrant pine.Source: medical material Ji Yuan: be the root welding technology of Valerianaceae plant Radix Et Rhizoma Nardostachyos and jatamansi.Nature and flavor: acrid in the mouth; Sweet; Warm in nature.Gui Jing: return spleen; Stomach warp.Cure mainly: regulating QI to relieve pain; Activating spleen and strengthening stomach.Main abdominal distention; Not national diet; Toothache; Beriberi.Wang Haogu: reason vigour, degass strongly fragrant." detailed outline ": control beriberi knee joint and float, decoct soup drip washing.

Radix seu Folium Rubi Cochinchinensis: source: come from " thousand kinds, south China medical herbs ".Another name: little fierce tiger, chicken aciculum, Vietnam Shan Pao, Herba Rubi blinii, false Cortex Acanthopancis, cat piece muscle.Source: medical material Ji Yuan: be the root of rosaceous plant Radix seu FoliumRubi Cochinchinensis.Nature and flavor: bitter; Pungent; Temperature.Gui Jing: liver; Kidney channel.Cure mainly: expelling wind and removing dampness, promoting the circulation of QI to relieve pain.Main air pain of dampness syndrome, traumatic pain, lumbago and skelalgia.

Caulis Seu Radix Kadsurae Oblongifoliae: source: " mountain of papers Chinese herbal medicine ".Source: be rattan or the root of the cold meal rattan of Magnoliacea plant.The whole year can adopt, using fresh herb or dry.Nature and flavor: " mountain of papers Chinese herbal medicine ": " sweet, temperature." cure mainly: wind-damp dispelling, and the intestines and stomach, pain in circulation of qi promoting.Cure cold, rheumatic arthralgia, diarrhoea, vomiting, traumatic injury.1. " register planted by Guangxi medicine ": " root, stem: dispelling the wind and dampness pathogens, traumatic injury, knife injury, snakebite." 2. " mountain of papers Chinese herbal medicine ": " rattan: promoting the circulation of QI to relieve pain, expelling wind and removing dampness.Control gastroenteritis, flu, traumatic injury, rheumatalgia, fracture."

Radix osterici citriodori (Radix Angelicae Citriodorae): another name: golden pheasant pawl, JIZHUASHEN, fragrant Radix Peucedani, chicken feet Radix Peucedani, NINGMENGXIANG alkali grass, Radix Angelicae Dahuricae (Radix Heraclei Scabridi), Garcinia mangostana perfume, nine steps perfume.Source: Umbelliferae archangel Radix osterici citriodori (Radix Angelicae Citriodorae) Angelica citriodora Hance., is used as medicine with root.The whole year can adopt, and is good to adopt quality autumn, clean using fresh herb or dry, air-dry section.Nature and flavor: pungent, bitter, tepor.Cure mainly: promoting the circulation of QI to relieve pain, promoting blood circulation to remove blood stasis, eliminating damp, detoxifying.For stomachache, stomachache, angina pectoris, headache, rheumatic ostalgia, traumatic injury, colic, bronchitis, cirrhotic ascites, amenorrhea, amebic dysentery, parotitis, venom.

Radix Aristolochiae: source: come from " book on Chinese herbal medicine covers bamboo fish trap ".Another name: Semen Oroxyli root, Semen Oroxyli root, radix aristolochiae, root Yunnan root of walking alone, Radix Inulae, Radix Aristolochiae, Fructus Aristolochiae root, Rohdea japonica, acute diseases such as cholera and sunstroke medicine, wild Radix Aucklandiae root, water Radix Aucklandiae root, white Radix Aristolochiae, Herba Aristolochiae root.Source: medical material Ji Yuan: be the root of aristolochiaceae plant Fructus Aristolochiae Aristolochia debilis Seib.et Zucc. and Aristolochia contorta Aristolochia contorta Bunge.Nature and flavor: pungent; Bitter; Cold in nature; Mild toxicity.Gui Jing: lung; Stomach warp.Cure mainly: promoting the circulation of QI to relieve pain, removing toxic substances and promoting subsidence of swelling, suppressing the hyperactive liver blood pressure lowering.Zhu Xiongxie institute abdomen pain, colicky, enteritis, dysentery is suffered from abdominal pain, cough phlegm dyspnea, snake bite and insect sting, carbuncle furuncle, eczema, skin pruritus, hypertension.

Rhizoma Curcumae: another name: Curcuma wenyujin, Rhizoma Curcumae, radix zedoariae, Rhizoma Trillii Tschonoskii, smelly dung Rhizoma Zingiberis Recens.Nature and flavor: pungent, bitter, temperature.Gui Jing: return liver, spleen channel.Cure mainly: circulation of qi promoting removing blood stasis, removing food stagnancy pain relieving.For Dan abdominal mass mass in the abdomen, blood stasis amenorrhea, food stagnation distending pain; Early cervical carcinoma.

Rhizoma Cyperi: source: " detailed outline ".Nature and flavor: pungent micro-hardship is sweet are flat.1. " not Lu ": " sweet in the mouth, is slightly cold, nontoxic." 2. amplification on Canon of Materia Medica: " bitter in the mouth." 3. " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " slightly warm in nature, acrid in the mouth." 4. " detailed outline ": " gas is put down, and the micro-hardship of acrid in the mouth is micro-sweet." return through: enter liver, tri-jiao channel.1. " detailed outline ": " brothers are silent cloudy, the few sun of hands, and row 12 of holding concurrently is through, eight arteries and veins edema caused by disorder of QI." 2. " Thunder God concocts property of medicine solution ": " enters lung, liver, spleen, stomach four warp." cure mainly: resolving depression of regulating the flow of vital energy, pain relieving regulating menstruation.Treating the liver discomfort in the stomach, depression of QI, breast abdomen distending pain over the hypochondrium, phlegm retention feeling of fullness, menoxenia, bleeding not during menses.(1) to regulate the flow of vital energy resolving depression: for the breast side of body and the stomach abdominal distention and pain of depression of liver-QI.(2) menstruction regulating and pain relieving: for menoxenia, the lower abdominal distention pain of depression of liver-QI.1. " not Lu ": " main except feverish sensation in the chest, fill fur, take sharp people for a long time, QI invigorating, long man." 2. Tang Materia Medica: " large therapeutic method to keep the adverse QI flowing downwards, except breast heat in the abdomen." 3. " medicine origin ": " fast gas." 4. Li Gao: " controls all gas, and the stomachache and cholera is vomited and diarrhoea, kidney qi, bladder is cold, removing stagnancy of indigested food and making QI downward." 5. Materia Medica of Decoction: " controls metrorrhagia." 6. " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " adjusts the gas in blood, and dissipating depression of QI, alleviating distention in middle-JIAO, helps digestion, anti-nausea." 7. " detailed outline ": " loose seasonal epidemic pathogens is trembled with fear epidemic disease, and profit three is burnt, and separate six kinds of stagnation-syndromes, the diet that disappears gathers, phlegm retention feeling of fullness, edema of dorsum of the foot, abdominal distention, beriberi, only trusted subordinate, limbs, head, order, tooth, all pains of ear, ulcer sores, spits blood, hematochezia, hematuria, married woman's bleeding not during menses, the moon wait uncomfortable, before tire puerperal all kinds of diseases and ailments."

Semen Sinapis Albae: source: come from Tang Materia Medica.Another name: hot food.Source: medical material Ji Yuan: be the seed of crucifer Caulis et Folium Sinapis albee Sinapis alba L..Nature and flavor: pungent; Temperature.Gui Jing: lung; Liver; Spleen; Stomach; Pericardium channel.Cure mainly: reduce phlegm by drink; Mass dissipating and swelling eliminating.Main cough with asthma abundant expectoration; Fullness in the chest and hypochondriac pain; Numb limbs and tense tendons; Arthralgia; Multiple abscess caused by damp-phlegm; Carbuncle of yin nature toxic swelling.

Cortex Magnoliae Officinalis: another name: Cortex Magnoliae Officinalis, CORTEX MAGNOLIAE OFFICINALIS.Source: this product is the dry dried bark of Magnoliacea plant Cortex Magnoliae Officinalis Magnolia officinalis Rehd. et Wils. or magnolia officinalis rehd.et wils.var.biloba rehd.et wils. Magnolia officinalis Rehd. et Wils. var. biloba Rehd. et Wils., root bark and branch skin.4 ~ June strips, root bark and branch skin Directly Dried in Shadow; Dried bark put in boiling water micro-boil after, dark and damp place of banking up, when " diaphoresis " is to inner surface purpling brown or sepia, steams soft, takes out, is rolled into tubular, dry.Nature and flavor: bitter, pungent, temperature.Gui Jing: return spleen, stomach, lung, large intestine channel.Cure mainly: dampness expectorant, the therapeutic method to keep the adverse QI flowing downwards is except full.For humidity hysteresis damaging the spleen and stomach, gastral cavity painful abdominal mass is vomited and diarrhoea, and stagnation of QI due to dyspepsia, abdominal distention constipation, phlegm retention is breathed with cough.

The Rhizoma Pinelliae: another name: the SANYE Rhizoma Pinelliae, SANYE are old, three step jumpings, numb semen myristicae, swallow tail.Source: this product is the dry tuber of aroid Rhizoma Pinelliae Pinellia ternata (Thunb.) Breit..Summer, Qiu Erji excavate, and clean, and removing crust and fibrous root, dry.Nature and flavor: pungent, temperature; Poisonous.Gui Jing: return spleen, stomach, lung meridian.Cure mainly: drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.For abundant expectoration cough with asthma, phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, syncope due to accumulation of phlegm is had a headache, vomiting regurgitation, and breast gastral cavity painful abdominal mass is vexed, globus hystericus; Raw with external treatment carbuncle sucutaneous nodule.Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) is used for stopping nausea and vomiting by lowering the adverse flow of QI.

Parmelia saxatilis Ach.: source: " vegetation is side just ".Nature and flavor: sweet, cold.1. " Shanxi Chinese medicinal herbal ": " micro-sweet, nontoxic." 2. " Chongqing medical herbs ": " bitter in the mouth, cold in nature, nontoxic." cure mainly: nourish blood, improving eyesight, the kidney invigorating, diuresis, heat clearing away, removing toxic substances.Control blurred vision, spit blood, metrorrhagia, lumbocrural pain, urine burning pain, nebulousurine, leucorrhea, burn.1. " vegetation is side just " " improving eyesight, benefit essence, reduces phlegm, relieving heat toxin, promoting the production of body fluid to quench thirst.Profit throat, is coated with chilblain, burn." 2. " Shanxi Chinese medicinal herbal ": " clear heat of the diaphragm, diuresis, dissipating phlegm for eliminating goiter, improving eyesight of enriching blood, benefit god increases marrow." 3. " Chongqing medical herbs ": " controls knife injury." 4. " Shandong Chinese herbal medicine handbook ": " the kidney invigorating, strengthening bone and muscle." 5. " the conventional Chinese herbal medicine handbook in the north ": " nourishing blood for improving eyesight, benefit essence, strengthening bone and muscle, eliminate indigestion gathers.Control blurred vision, lumbago and skelalgia, enclosed mass in abdomen, hepatitis." 6. " Jilin Chinese herbal medicine ": " invigorating the spleen and replenishing QI, damp eliminating diuresis, removing heat-phlegm.Control damp-heat in the urinary bladder, jaundice, incised wound, waist lower limb is air-cooled, metrorrhagia."

Pyritum: nature and flavor: pungent is flat.Gui Jing: return Liver Channel.Cure mainly: dissipating blood stasis, synthetism, pain relieving.For tumbling and swelling, injured bone.

Rhizoma Dioscoreae Bulbiferae: source: " Bencao Tujing ".Another name: xanthate (" Japan hanako materia medica "), xanthate root (" Kaibao Bencao "), Myrrha, large bitter (" detailed outline ").Source: be the tuber of Dioscoreaceae plant Dioscorea bulbifera L..Nature and flavor: bitter are flat.1. " Japan hanako materia medica ": " cool." 2. " Kaibao Bencao ": " is bitter, flat, nontoxic." 3. " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " property Great Cold, bitter in the mouth." return through: " Bencao Jingshu ": " start with few the moon, meridian of Foot-JUE YIN." cure mainly: removing heat from blood, pathogenic fire reducing, disappear wart, removing toxic substances.Control haematemesis, epistaxis, sore throat, goiter, carbuncle sore scrofula.1. " Kaibao Bencao ": " main all evils swell skin ulcer fistula, sore throat, and Serpentis dog stings poison, get root and grind and take it, also containing being also coated with." 2. " detailed outline ": " removing heat from blood, pathogenic fire reducing, disappear anxiety, removing toxic substances." 3. " medicine will is planted in Jiangsu ": " controls soreness of waist pain."

Pumex: source: 1. Pumex begins to be loaded in " solar corona ".2. " praise and help book on Chinese herbal medicine " under investing " Fossilia Brachyurae ".3. " detailed outline " is said: " with the passing of time Pumex is fine sand foam cohesion between sea, river, does not form person.Shape, as foam and Stalactitum, has pore as moth nest, white, and body is empty and light.It is very wonderful that modern skin makes Household milling scurf.Marine person's salty in the mouth, is used as medicine better." 4. " detailed outline " draw again " hand over state to note " cloud: " marinely have Pumex, light void can mill pin, quenching the thirst of drink to boil water, and namely this is also." by Pumex be volcano ejection magma, give out many pores stone of volume gas when it solidifies, conform to therewith described in above document.Nature and flavor: salty; Cold; Nontoxic.Gui Jing: lung; Kidney; Liver; Large intestine channel.Cure mainly: lung heat clearing fire; Change old expectorant; Relieving stranguria by diuresis; Hard masses softening and resolving.Main phlegm-heat obstructing in the lung; The thick difficulty of cough with asthma expectorant is coughed up; The puckery pain of dribbling urination; Goiter scrofula.

Rhizoma Chuanxiong: another name: rhizome of chuanxiong Qiong, Rhizoma Chuanxiong.Nature and flavor: pungent, temperature.Gui Jing: return liver, gallbladder, pericardium channel.Cure mainly: blood-activating and qi-promoting, wind-expelling pain-stopping.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.

Flos Campsis: another name: Radix campsis, Herba Ipomoeae Cairicae, Flos Carthami Thalictrum omeiense W. T. Wang et S. H. Wang, fuchsia, the dragon that climbs the tree, Hedera nepalensis var. sinensis, white Canis familiaris L. intestinal, hanging screen flower, induced abortion flower.Source: this product is reach the clouds the dried floral of Campsis radicans (L.) Seem. and root in reach the clouds Campsis grandiflora (Thunb.) K. Schum. or America of bavin Wei section plant.Summer, Qiu Erji gather when spending in full bloom, dry.Root is adopted spring and autumn, and clean, section is dried.Nature and flavor: flower: sweet, sour, cold.Root: bitter, cool.Gui Jing: flower: return liver, pericardium channel.Cure mainly: flower: removing heat from blood, blood stasis dispelling, dispels the wind.For menoxenia, Jing Bi WEIJIA, puerperal swelling of the breast, rubella is rubescent, skin pruritus, acne.Root: promoting blood circulation to remove blood stasis, removing toxic substances and promoting subsidence of swelling.For rheumatic arthralgia, traumatic injury, fracture, dislocation, acute gastroenteritis.

Radix berchemiae lineatae: another name: molluscum contagiosum root, Ramulus et Folium Berchemiae Lineatae, public blue or green, the oolong root origin of duck: Rhamnaceae hook fold plant spire Radix Berchemiae Giraldianae Berchemia lineata (L.) DC., is used as medicine with root.The whole year can adopt, and cleans section, dries.Nature and flavor: micro-hardship, puckery are flat.Cure mainly: removing stasis to stop bleeding, antitussive pain relieving.For hemoptysis of pulmonary tuberculosis, taste-blindness rate is hemorrhage, schizophrenia, traumatic injury, rheumatic ostalgia, furuncle furuncle and phyma, deradenoncus, painful and swollen testis.

Fructus Bruceae: source: 1. supplementary Amplifications of the Compendium of Materia Medica: Fructus Bruceae, goes out Fujian, extensively, medicine all has it wantonly.Shape is as Firmiana simplex seed, and its core heavy wool, eats raw and make us telling, and makes frost, beats and deoil, be used as medicine good.Nature and flavor: bitter in the mouth; Cold in nature; Mild toxicity.Gui Jing: large intestine; Liver Channel.Cure mainly: heat clearing away; Removing toxic substances; Parasite killing; Preventing the attack (or recurrence) of malaria; .Main toxic-heat and blood stasis; Cold-dysentery; Chronic dysentery with frequent relapse; Malaria; Hemorrhoid; Carbuncle; Pudendal pruritus; Leucorrhea; Wart wart; Clavus.

Rhizoma Sparganii: source: come from supplementary Amplifications of the Compendium of Materia Medica.Nature and flavor: acrid in the mouth; Puckery; Cool.Gui Jing: liver; Spleen channel.Cure mainly: removing blood stasis circulation of qi promoting; Removing food stagnancy pain relieving.Primary symptom abdominal mass mass in the abdomen; The stagnant amenorrhea of the stasis of blood; Dysmenorrhea; Food stagnation distending pain; Fall the year pain of injury.

Radix Achyranthis: source: " Bencao Tujing ".Another name: Du's Radix Achyranthis Bidentatae (essentials of Matea Medica).Source: be the wild species of amaranthaceous plant Radix Achyranthis Bidentatae and the root welding technology of achyranthes longifolia Makino, coarse wool Radix Achyranthis Bidentatae etc.Between Winter-Spring or excavate autumn, removing stem and leaf and fibrous root, clean, dry or smoked with sulfur after dry.Nature and flavor: picric acid are flat.1. " Fujian traditional herbal medicine ": " picric acid is flat, nontoxic.The acid of " 2. " Guangxi Chinese herbal medicine ": " mildly bitter flavor, cold in nature, nontoxic." 3. " Yunnan Chinese herbal medicine ": " sweet micro-acid, cool." cure mainly: promoting blood circulation to remove blood stasis, damp eliminating is favorable to the people, heat-clearing and toxic substances removing.Control gonorrhea, hematuria, women's amenorrhea, lump in the abdomen, rheumatic arthritis, beriberi, edema, dysentery, malaria, diphtheria, carbuncle, traumatic injury.1. " Bencao Tujing ": " control married woman's clot." 2. " detailed outline is picked up any lost article from the road ": " blood circulation promoting and blood stasis dispelling, wide muscle, reason traumatic injury.Control tetanus, foul disease as 72.Is produced from merit victory river.Again: kindly can manage skin ulcer, and arrow incarnation."

Caulis Sargentodoxae: source: " simple and easy medical herbs ".1. " Zhejiang traditional herbal medicine ": " property is put down, sour-puckery flavor." 2. " Traditional Chinese Medicine in Sichuan will ": " is cool in nature, and bitter in the mouth is nontoxic." return through: " Traditional Chinese Medicine in Sichuan will ": " enters liver.Large intestine two warp." cure mainly: relieve internal heat eliminating carbuncle, promoting blood circulation to remove obstruction in the collateral, wind dispelling insecticide.Control acute and chronic appendicitis, rheumatic arthralgia, bloody dysentery, stranguria with blood, menoxenia, infantile malnutrition, worm pain, injury from falling down.Heat-clearing and toxic substances removing, invigorates blood circulation, and dispels the wind.Pain is flutterred for abdominalgia with intestinal abscess, amenorrhea dysmenorrhea, rheumatic arthralgia, traumatic injury.1. " Bencao Tujing ": " attack blood, control clot." 2. " simple and easy medical herbs ": " controls bones and muscles pain, chases after wind, strong waist knee joint, tonifying YANG thing." 3. " Chinese medicinal herbal ": " dispel the wind the meridian dredging, diuresis parasite killing.Control acute appendicitis, rheumatic arthralgia, leprosy, gonorrhea: ascarid is suffered from abdominal pain." 4. " Hunan medicine will ": " is stimulated the menstrual flow and is enriched blood, bone and muscle strengthening, anthelmintic.Control traumatic injury, rheumatalgia, bruise, stranguria with blood, bones and muscles pain, furuncle, filaricide." 5. " east, Fujian book on Chinese herbal medicine " " controls trusted subordinate's angor, dysentery." 6. Guangzhou army " conventional Chinese herbal medicine handbook ": " controls podomere and aches, and numbness contracture, edema, blood deficiency is dizzy." 7. " Shaanxi Chinese herbal medicine ": " anti-inflammation, dispersing swelling and dissipating binds, vital energy regualting and blood circulation-promoting, wind dispelling insecticide.Appendicitis curing, menoxenia, metrorrhagia, infantile malnutrition, ascarid, pinworm disease."

Radix Aconiti Vaginati: source: " Guizhou folk medicine ".Nature and flavor: " Guizhou folk medicine ": " warm in nature, acrid in the mouth." cure mainly: control cough with asthma, menoxenia, traumatic injury.1. " Guizhou folk medicine ": " promoting blood flow to regulate menstruation, pain relieving." 2. control traumatic injury, reduce phlegm, cough-relieving is breathed heavily.Innominate toxic swelling is wiped in external.

Caulis Akebiae: source: come from " property of medicine opinion ".Nature and flavor: bitter; Cold in nature.Gui Jing: the heart; Spleen; Kidney; Small intestinal; Urinary bladder channel.Cure mainly: clearing away heat and promoting diuresis; Blood circulation and channel invigorating.Main red urine is red; Stranguria with turbid discharge; Edema; Irritable feverish sensation in the chest; Larynx larynx pain; Aphtha of the mouth and tongue; Rheumatic arthralgia; Galactostasis; Amenorrhea; Dysmenorrhea.

In described medicine, the ratio of weight and number of each raw medicinal material is: Radix Aconiti Vaginati 15-35 part, Caulis Akebiae 10-20 part, Radix Achyranthis 14-32 part, Caulis Sargentodoxae 18-37 part, Rhizoma Sparganii 13-27 part, Radix berchemiae lineatae 15-40 part, Rhizoma Chuanxiong 11-31 part, Rhizoma Acori Calami 15-25 part, Pumex 13-32 part, Fructus Pruni persicae immaturus 2-3 part, Rhizoma Dioscoreae Bulbiferae 12-22 part, Pyritum 14-36 part, Parmelia saxatilis Ach. 11-21 part, Rhizoma Pinelliae 2-3 part, Cortex Magnoliae Officinalis 16-38 part, Semen Canavaliae 18-42 part, Semen Sinapis Albae 13-33 part, Rhizoma Cyperi 14-28 part, Rhizoma Curcumae 10-30 part, Herba Mimosae Pudicae 3-5 part, Radix osterici citriodori (Radix Angelicae Citriodorae) 12-24 part, Caulis Seu Radix Kadsurae Oblongifoliae 17-36 part, Radix seu Folium Rubi Cochinchinensis 15-25 part, Radix Et Rhizoma Nardostachyos 11-33 part, Caulis Hederae Sinensis 16-28 part, Semen Raphani 11-31 part and Semen Arecae 14-24 part.

In described medicine, the ratio of weight and number of each raw medicinal material is: Radix Aconiti Vaginati 24 parts, Caulis Akebiae 15 parts, Radix Achyranthis 32 parts, Caulis Sargentodoxae 20 parts, Rhizoma Sparganii 17 parts, Radix berchemiae lineatae 35 parts, Rhizoma Chuanxiong 23 parts, Rhizoma Acori Calami 20 parts, Pumex 28 parts, Fructus Pruni persicae immaturus 2 parts, Rhizoma Dioscoreae Bulbiferae 22 parts, Pyritum 34 parts, Parmelia saxatilis Ach. 21 parts, the Rhizoma Pinelliae 2 parts, Cortex Magnoliae Officinalis 38 parts, Semen Canavaliae 40 parts, Semen Sinapis Albae 33 parts, Rhizoma Cyperi 21 parts, Rhizoma Curcumae 18 parts, Herba Mimosae Pudicae 3 parts, Radix osterici citriodori (Radix Angelicae Citriodorae) 22 parts, Caulis Seu Radix Kadsurae Oblongifoliae 30 parts, Radix seu Folium Rubi Cochinchinensis 20 parts, Radix Et Rhizoma Nardostachyos 33 parts, Caulis Hederae Sinensis 25 parts, Semen Raphani 31 parts and Semen Arecae 24 parts.

In described medicine, the ratio of weight and number of each raw medicinal material is: Radix Aconiti Vaginati 33 parts, Caulis Akebiae 20 parts, Radix Achyranthis 24 parts, Caulis Sargentodoxae 35 parts, Rhizoma Sparganii 24 parts, Radix berchemiae lineatae 25 parts, Rhizoma Chuanxiong 30 parts, Rhizoma Acori Calami 17 parts, Pumex 32 parts, Fructus Pruni persicae immaturus 2 parts, Rhizoma Dioscoreae Bulbiferae 14 parts, Pyritum 26 parts, Parmelia saxatilis Ach. 18 parts, the Rhizoma Pinelliae 3 parts, Cortex Magnoliae Officinalis 26 parts, Semen Canavaliae 35 parts, Semen Sinapis Albae 25 parts, Rhizoma Cyperi 18 parts, Rhizoma Curcumae 30 parts, Herba Mimosae Pudicae 3 parts, Radix osterici citriodori (Radix Angelicae Citriodorae) 12 parts, Caulis Seu Radix Kadsurae Oblongifoliae 36 parts, Radix seu Folium Rubi Cochinchinensis 25 parts, Radix Et Rhizoma Nardostachyos 11 parts, Caulis Hederae Sinensis 20 parts, Semen Raphani 31 parts and Semen Arecae 16 parts.

Described medicine also comprises: Herba veronicae, Flos Campsis, Fructus Bruceae, Radix Aristolochiae and Herba Kalimeridis.

In described medicine, the ratio of weight and number of each raw medicinal material is: Radix Aconiti Vaginati 15-35 part, Caulis Akebiae 10-20 part, Radix Achyranthis 14-32 part, Caulis Sargentodoxae 18-37 part, Rhizoma Sparganii 13-27 part, Radix berchemiae lineatae 15-40 part, Rhizoma Chuanxiong 11-31 part, Rhizoma Acori Calami 15-25 part, Pumex 13-32 part, Fructus Pruni persicae immaturus 2-3 part, Rhizoma Dioscoreae Bulbiferae 12-22 part, Pyritum 14-36 part, Parmelia saxatilis Ach. 11-21 part, Rhizoma Pinelliae 2-3 part, Cortex Magnoliae Officinalis 16-38 part, Semen Canavaliae 18-42 part, Semen Sinapis Albae 13-33 part, Rhizoma Cyperi 14-28 part, Rhizoma Curcumae 10-30 part, Herba Mimosae Pudicae 3 parts, Radix osterici citriodori (Radix Angelicae Citriodorae) 12-24 part, Caulis Seu Radix Kadsurae Oblongifoliae 17-36 part, Radix seu Folium Rubi Cochinchinensis 15-25 part, Radix Et Rhizoma Nardostachyos 11-33 part, Caulis Hederae Sinensis 16-28 part, Semen Raphani 11-31 part, Semen Arecae 14-24 part, Herba veronicae 13-35 part, Flos Campsis 10-20 part, Fructus Bruceae 3-5 part, Radix Aristolochiae 1-2 part and Herba Kalimeridis 15-38 part.

In described medicine, the ratio of weight and number of each raw medicinal material is: Radix Aconiti Vaginati 20 parts, Caulis Akebiae 15 parts, Radix Achyranthis 32 parts, Caulis Sargentodoxae 28 parts, Rhizoma Sparganii 24 parts, Radix berchemiae lineatae 40 parts, Rhizoma Chuanxiong 31 parts, Rhizoma Acori Calami 16 parts, Pumex 32 parts, Fructus Pruni persicae immaturus 2 parts, Rhizoma Dioscoreae Bulbiferae 21 parts, Pyritum 36 parts, Parmelia saxatilis Ach. 14 parts, the Rhizoma Pinelliae 2 parts, Cortex Magnoliae Officinalis 38 parts, Semen Canavaliae 42 parts, Semen Sinapis Albae 33 parts, Rhizoma Cyperi 28 parts, Rhizoma Curcumae 16 parts, Herba Mimosae Pudicae 3 parts, Radix osterici citriodori (Radix Angelicae Citriodorae) 22 parts, Caulis Seu Radix Kadsurae Oblongifoliae 36 parts, Radix seu Folium Rubi Cochinchinensis 25 parts, Radix Et Rhizoma Nardostachyos 33 parts, Caulis Hederae Sinensis 22 parts, Semen Raphani 30 parts, Semen Arecae 20 parts, Herba veronicae 35 parts, Flos Campsis 12 parts, Fructus Bruceae 3 parts, Radix Aristolochiae 2 parts and Herba Kalimeridis 38 parts.

When the dosage form of described medicine is honey refining pill, its preparation method comprises the following steps:

When the dosage form of described medicine is capsule, its preparation method comprises the following steps:

Embodiment 1 honey refining pill

The manufacturing process of the present invention's honey refining pill is: get Radix Aconiti Vaginati 240g, Caulis Akebiae 150g, Radix Achyranthis 320g, Caulis Sargentodoxae 200g, Rhizoma Sparganii 170g, Radix berchemiae lineatae 350g, Rhizoma Chuanxiong 230g, Rhizoma Acori Calami 200g, Pumex 280g, Fructus Pruni persicae immaturus 20g, Rhizoma Dioscoreae Bulbiferae 220g, Pyritum 340g, Parmelia saxatilis Ach. 210g, Rhizoma Pinelliae 20g, Cortex Magnoliae Officinalis 380g, Semen Canavaliae 400g, Semen Sinapis Albae 330g, Rhizoma Cyperi 210g, Rhizoma Curcumae 180g, Herba Mimosae Pudicae 30g, Radix osterici citriodori (Radix Angelicae Citriodorae) 220g, Caulis Seu Radix Kadsurae Oblongifoliae 300g, Radix seu Folium Rubi Cochinchinensis 200g, Radix Et Rhizoma Nardostachyos 330g, Caulis Hederae Sinensis 250g, Semen Raphani 310g and Semen Arecae 240g,

Second step, again surplus stock medical material is mixed in proportion, add 85% soak with ethanol 1 hour, the heating extraction 2 times relative to mixture 4 times amount, each 0.7 hour, filter to obtain extracting solution, medicinal residues are for subsequent use, merge extractive liquid, be the ultrafiltration post ultrafiltration of 70000 again through the molecular weight that dams, ultrafiltration decompression removing ethanol, during simmer down to 90 DEG C, relative density is the extractum of 1.03, becomes component 1;

Medicinal residues obtained above are added 2 times amount water soaking 1.5 hours by the 3rd step, within 1.0 hours, extract 1 time, are the extractum of 1.1, as component 2 by relative density during extracting solution heating under reduced pressure simmer down to 85 DEG C;

Embodiment 2 capsule

The manufacturing process of capsule of the present invention is: get Radix Aconiti Vaginati 330g, Caulis Akebiae 200g, Radix Achyranthis 240g, Caulis Sargentodoxae 350g, Rhizoma Sparganii 240g, Radix berchemiae lineatae 250g, Rhizoma Chuanxiong 300g, Rhizoma Acori Calami 170g, Pumex 320g, Fructus Pruni persicae immaturus 20g, Rhizoma Dioscoreae Bulbiferae 140g, Pyritum 260g, Parmelia saxatilis Ach. 180g, Rhizoma Pinelliae 30g, Cortex Magnoliae Officinalis 260g, Semen Canavaliae 350g, Semen Sinapis Albae 250g, Rhizoma Cyperi 180g, Rhizoma Curcumae 300g, Herba Mimosae Pudicae 30g, Radix osterici citriodori (Radix Angelicae Citriodorae) 120g, Caulis Seu Radix Kadsurae Oblongifoliae 360g, Radix seu Folium Rubi Cochinchinensis 250g, Radix Et Rhizoma Nardostachyos 110g, Caulis Hederae Sinensis 200g, Semen Raphani 310g and Semen Arecae 160g,

The first step, is mixed in proportion each for described Chinese medicine raw medicinal material, and adding relative to the determining alcohol of mixture quality 3 times is the ethanol of 90%, reflux hour, extracts, and filters acquisition first extracting solution; It is the ethanol of 85% that the medicinal residues that filtration obtains add relative to the determining alcohol of described medicinal residues quality 2 times again, reflux 2 hours, extracts, and filters acquisition second extracting solution; First extracting solution and the second extracting solution are merged, concentrating under reduced pressure removing alcohol solvent, dry, obtain and get dry extract;

Second step, is placed on the dry cream that the first step obtains in super micron mill and pulverizes 2 hours, pulverize, sieve, obtain 380 object micropowders;

3rd step, adds Pulvis Talci, magnesium stearate successively in the micropowders that second step obtains, and carries out mixing process, obtains capsule 's content; Described micropowders, magnesium stearate and talcous weight ratio are 100: 0.3:0.5, incapsulate in housing by described capsule 's content, obtain capsule finished product.

Embodiment 3 decoction

The manufacturing process of decoction of the present invention is: get Radix Aconiti Vaginati 200g, Caulis Akebiae 150g, Radix Achyranthis 320g, Caulis Sargentodoxae 280g, Rhizoma Sparganii 240g, Radix berchemiae lineatae 400g, Rhizoma Chuanxiong 310g, Rhizoma Acori Calami 160g, Pumex 320g, Fructus Pruni persicae immaturus 20g, Rhizoma Dioscoreae Bulbiferae 210g, Pyritum 360g, Parmelia saxatilis Ach. 140g, Rhizoma Pinelliae 20g, Cortex Magnoliae Officinalis 380g, Semen Canavaliae 420g, Semen Sinapis Albae 330g, Rhizoma Cyperi 280g, Rhizoma Curcumae 160g, Herba Mimosae Pudicae 30g, Radix osterici citriodori (Radix Angelicae Citriodorae) 220g, Caulis Seu Radix Kadsurae Oblongifoliae 360g, Radix seu Folium Rubi Cochinchinensis 250g, Radix Et Rhizoma Nardostachyos 330g, Caulis Hederae Sinensis 220g, Semen Raphani 300g, Semen Arecae 200g, Herba veronicae 350g, Flos Campsis 120g, Fructus Bruceae 30g, Radix Aristolochiae 20g and Herba Kalimeridis 380g,

The first step: purple casserole is put in described raw medicinal material mixing, adds clear water, to clear water dipped medical material upper surface 3cm, soak 7 hours;

Second step: purple casserole is placed on fire, after intense fire boils, using slow fire instead, to decoct the 45 minutes dosage to medicinal liquid be slowly 250ml, filters, obtain filtrate a, for subsequent use;

3rd step: residue medicinal residues are added clear water again, to clear water dipped medical material upper surface 3cm, soaks 7 hours;

4th step: be placed in by purple casserole on fire, after intense fire boils, using slow fire instead, to decoct the 30 minutes dosage to medicinal liquid be slowly 200ml, filters, obtain filtrate b, mixed and obtain decoction by filtrate a and filtrate b.

Acute toxicity test: application NIH mice 40, S recovery from illness F level, male and female half and half, body weight 18 ~ 25g, carries out acute toxicity test.Mice is divided into two groups at random, often organizes 20, i.e. matched group and administration group, fasting 12 hours before experiment; The banburying pill prepared by embodiments of the invention 1 is dissolved in water, (concentration is 5.74g crude drug/ml, maximum concentration) gavage, gavage volume is 5ml/kg(and unit dosage form is 28.7 crude drugs/kg), matched group gives normal saline, administration in a day 2 times, delivery time 6 hours, Continuous Observation 14 days after administration, and record mice toxic reaction and death toll.Experimental result shows: compare with matched group, and after administration, mice has no notable difference, and experiment Continuous Observation 14 days, mouse systemic situation, diet, drinking-water, body weight increase all normal.Mouse oral gavage banburying pill of the present invention LD50>28.7 crude drug/kg, every day, maximum dosage-feeding was 57.4 crude drugs/kg/ day.Clinical drug dosage of the present invention be 4.6g crude drug/day/people, adult body weight in 60KG, average dosage is 0.077g crude drug/kg/ day.By weighing machine: the dosis tolerata of mice (average weight is in 21g) oral administration gavage pharmaceutical composition of the present invention is 745 times of quantity.Therefore pharmaceutical composition acute toxicity of the present invention is low, clinical drug safety.

Cumulative toxicity test: select 20 healthy mices, female, each 10 of hero, with the capsule of the embodiment of the present invention 2 for object, dose design is first phase in every 5 days, each issue dosage is respectively 0.10LD50,0.15LD50,0.22LD50,0.34LD 50,0.50LD50, the LD 50 that is female, male mice of this sample be 5000m part/k part BW (five dosage is 500,750,1100,1700,2500m part/k part BW).Within every 5 days, weigh once, adjustment dosage, by 0.1ml/10 part BW per os gavage.After 20 days, animal occurs without death condition, off-test, and by ascending-dose to tested material after 20 days, female, buck all occurs without death condition.

Long term toxicity test: the decoction of the embodiment of the present invention 3 is pressed 6.43,15.72 and 36.41g crude drug/kg continuous use 16 weeks (1.0ml/100g body weight to mice, every day 2 times) and drug withdrawal after 4 weeks, result shows: the index such as hair, behavior, defecation, body weight, organ weights, hemogram, hepatic and renal function, blood glucose, blood fat of medicine of the present invention to mice all has no significant effect, internal organs naked eyes do not find that difference change and histological indications show, medication 16 weeks and drug withdrawal are after 4 weeks, and Organs of Mice is all without obviously changing.Illustrate that pharmaceutical composition of the present invention is little to toxicity after mice long-term prescription, also there is no difference reaction after drug withdrawal, application safety.

Clinical data:

Case selection: the patient fetching the 260 routine infantile hernias coming from the court in October ,-2014 in October, 2013, wherein man 174 example, female 86 example, the mean age (2.2) year; All patients is all through the patient of operation, indirect inguinal hernia 197 example, straight hernia 63 example, and all patients are not statistically significant in age, sex, body weight and height etc., has comparability; Banburying pill treatment group, capsule treatment group, decoction treatment group and matched group are divided at random to 260 routine patients, each experimental group 65 people.

Diagnostic criteria:

Clinical symptoms: (1) infantile hernia likely can occur after a couple of days, several months or several years after birth.(2) usually cry and scream child, strenuous exercise, constipation with dry stool time, have the swollen thing of a projection bulk at groin place, extend to scrotum or labial regions sometimes; Can die away when lying low or press with hands.(3) once hernia block generation incarceration (hernia enclosed mass cannot Hui Na), there will be stomachache, Nausea and vomiting, fever, anorexia or cry and scream, dysphoria.(4) infantile hernia their early stage, the thing that swells when the flat sleeping peace and quiet of child can disappear; Along with intraabdominal pressure continue increase, swollen thing can drop in scrotum.If at this moment can remove the factor that intra-abdominal pressure increases, and make infant flat sleeping, or the thing that will swell lightly pushes toward direction, abdominal cavity, swollen thing then turns back to abdominal cavity by that passage during testicular descent, and swollen thing disappears, and this situation is called recoverability hernia.(5) if swollen thing can not return and receive abdominal cavity, just there will be stomachache aggravation, crying and screaming more than, then occur the ileus symptoms such as vomiting, abdominal distention, defecation be not smooth, visible oval swollen body thing in groin or scrotum, quality is hard, touches a tender spot obvious; Incarceration person of long duration skin is red and swollen as seen, receives, likely occur the severe complications such as intestinal tube ischemic necrosis if long-time intestinal tube can not return.

Efficacy assessment standard: effective: transference cure, body constitution recovers normal, observes 1 year without recidivist; Take a turn for the better: symptom is clearly better, and symptom fades away; Invalid: not reach improvement standard person.

Therapeutic Method:

In medicine composite for curing group:

Banburying pill treatment group: use banburying pill prepared by the embodiment of the present invention 1, every day 3 times, 2 balls every 5 days are 1 course for the treatment of;

Capsule treatment group: take the embodiment of the present invention 2 prepare capsule, every day 3 times, one time 2, within every 5 days, be a course for the treatment of;

Decoction treatment group: use decoction prepared by the embodiment of the present invention 3, every day 2 times, 160g/ time every 5 days is a course for the treatment of.

Matched group: use ball in the reason of ginseng osmanthus, every day 3 times, 2 balls every 5 days are a course for the treatment of.

Therapeutic outcome:

See table 1 and table 2, as can be seen from Table 1, adopt medicine composite for curing infantile hernia of the present invention, relative to conventional medicament on therapeutic effect, there is significant improvement; As can be seen from Table 2, adopt medicine composite for curing infantile hernia of the present invention, relative to conventional medicament, treatment the course for the treatment of on significantly shorten.

After each group of table 1 treats 4 courses for the treatment of respectively, Clinical efficacy comparison is routine

Group	Number of cases	Effective number	Good revolution	Invalid number	Total effective rate (%)
						Banburying pill treatment group	65	61	3	1	98.5％
Capsule treatment group	65	60	3	2	97％
						Decoction treatment group	65	63	2	0	100％
Matched group	65	44	11	10	84.6％

Table 2 Four composition is effective and improvement number time comparative example (%) after not treating 4 courses for the treatment of

Group	Number of cases	1st course for the treatment of	2nd course for the treatment of	3rd course for the treatment of	4th course for the treatment of
						Banburying pill treatment group	64	14（21.9％）	15（23.4％）	17（26.6％）	18（28.1％）
Capsule treatment group	63	13（20.6％）	15（23.8％）	17（27％）	18（28.6％）
						Decoction treatment group	65	14（21.5％）	16（24.6％）	17（26.2％）	18（27.7％）
Matched group	55	3（10.1％）	5（14.5％）	7（20.3％）	40（55.1％）

According to the clinical statistics in above table, pharmaceutical composition provided by the invention have rapid-action, improvement rate is high, determined curative effect, safety are high, have no side effect; Simultaneously and improvement number effective to treatment group 192 examples and matched group is effective and the 55 routine follow-up of patients 1 year half that take a turn for the better, result is added up, effective 61 examples and take a turn for the better 3 examples all without recurring in banburying pill 64 example, and relapse rate is 0%; In capsule treatment group 63 example, effective 60 examples are without recurrence, 1 case relapsed in 3 examples that take a turn for the better, and relapse rate is 1.5%; In decoction treatment group 65 example, effective 63 examples and improvement 2 examples are all without recurrence, and relapse rate is 0%; Matched group is effective and improvement number 55 routine, recurs 7 examples in effective 44 routine patients, recurs 9 examples, relapse rate 29% in 11 routine patients of improvement; Above-mentioned recurrence refers to that patient outcomes reaches effective or after improvement, obviously occurs the symptom before treatment in 1 year half of following up a case by regular visits to.

Model case: Zhang, male, 2 years old, suffer from infantile hernia, often cry and scream more than, then occur the ileus symptoms such as vomiting, abdominal distention, defecation be not smooth, on inspection at the visible oval swollen body thing of groin, quality is hard, touches a tender spot obviously, be diagnosed as infantile hernia, after underwent operative, decoction prepared by the use embodiment of the present invention 3 taking Medications Example 3 of the present invention, every day 2 times, 160g/ time, treat and substantially cure a course for the treatment of, continue medication two weeks to cure, follow up a case by regular visits to and do not recur for 1 year half.

The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.

Claims

1. treat the pharmaceutical composition of infantile hernia for one kind, it is characterized in that, comprise following raw medicinal material: Radix Aconiti Vaginati, Caulis Akebiae, Radix Achyranthis, Caulis Sargentodoxae, Rhizoma Sparganii, Radix berchemiae lineatae, Rhizoma Chuanxiong, Rhizoma Acori Calami, Pumex, Fructus Pruni persicae immaturus, Rhizoma Dioscoreae Bulbiferae, Pyritum, Parmelia saxatilis Ach., the Rhizoma Pinelliae, Cortex Magnoliae Officinalis, Semen Canavaliae, Semen Sinapis Albae, Rhizoma Cyperi, Rhizoma Curcumae, Herba Mimosae Pudicae, Radix osterici citriodori (Radix Angelicae Citriodorae), Caulis Seu Radix Kadsurae Oblongifoliae, Radix seu Folium Rubi Cochinchinensis, Radix Et Rhizoma Nardostachyos, Caulis Hederae Sinensis, Semen Raphani and Semen Arecae.

2. the pharmaceutical composition for the treatment of infantile hernia according to claim 1, it is characterized in that, in described pharmaceutical composition, the ratio of weight and number of each raw medicinal material is: Radix Aconiti Vaginati 15-35 part, Caulis Akebiae 10-20 part, Radix Achyranthis 14-32 part, Caulis Sargentodoxae 18-37 part, Rhizoma Sparganii 13-27 part, Radix berchemiae lineatae 15-40 part, Rhizoma Chuanxiong 11-31 part, Rhizoma Acori Calami 15-25 part, Pumex 13-32 part, Fructus Pruni persicae immaturus 2-3 part, Rhizoma Dioscoreae Bulbiferae 12-22 part, Pyritum 14-36 part, Parmelia saxatilis Ach. 11-21 part, Rhizoma Pinelliae 2-3 part, Cortex Magnoliae Officinalis 16-38 part, Semen Canavaliae 18-42 part, Semen Sinapis Albae 13-33 part, Rhizoma Cyperi 14-28 part, Rhizoma Curcumae 10-30 part, Herba Mimosae Pudicae 3-5 part, Radix osterici citriodori (Radix Angelicae Citriodorae) 12-24 part, Caulis Seu Radix Kadsurae Oblongifoliae 17-36 part, Radix seu Folium Rubi Cochinchinensis 15-25 part, Radix Et Rhizoma Nardostachyos 11-33 part, Caulis Hederae Sinensis 16-28 part, Semen Raphani 11-31 part and Semen Arecae 14-24 part.

3. the pharmaceutical composition for the treatment of infantile hernia according to claim 1 and 2, it is characterized in that, in described pharmaceutical composition, the ratio of weight and number of each raw medicinal material is: Radix Aconiti Vaginati 24 parts, Caulis Akebiae 15 parts, Radix Achyranthis 32 parts, Caulis Sargentodoxae 20 parts, Rhizoma Sparganii 17 parts, Radix berchemiae lineatae 35 parts, Rhizoma Chuanxiong 23 parts, Rhizoma Acori Calami 20 parts, Pumex 28 parts, Fructus Pruni persicae immaturus 2 parts, Rhizoma Dioscoreae Bulbiferae 22 parts, Pyritum 34 parts, Parmelia saxatilis Ach. 21 parts, the Rhizoma Pinelliae 2 parts, Cortex Magnoliae Officinalis 38 parts, Semen Canavaliae 40 parts, Semen Sinapis Albae 33 parts, Rhizoma Cyperi 21 parts, Rhizoma Curcumae 18 parts, Herba Mimosae Pudicae 3 parts, Radix osterici citriodori (Radix Angelicae Citriodorae) 22 parts, Caulis Seu Radix Kadsurae Oblongifoliae 30 parts, Radix seu Folium Rubi Cochinchinensis 20 parts, Radix Et Rhizoma Nardostachyos 33 parts, Caulis Hederae Sinensis 25 parts, Semen Raphani 31 parts and Semen Arecae 24 parts.

4. the pharmaceutical composition of the treatment infantile hernia according to any one of claim 1-3, it is characterized in that, in described pharmaceutical composition, the ratio of weight and number of each raw medicinal material is: Radix Aconiti Vaginati 33 parts, Caulis Akebiae 20 parts, Radix Achyranthis 24 parts, Caulis Sargentodoxae 35 parts, Rhizoma Sparganii 24 parts, Radix berchemiae lineatae 25 parts, Rhizoma Chuanxiong 30 parts, Rhizoma Acori Calami 17 parts, Pumex 32 parts, Fructus Pruni persicae immaturus 2 parts, Rhizoma Dioscoreae Bulbiferae 14 parts, Pyritum 26 parts, Parmelia saxatilis Ach. 18 parts, the Rhizoma Pinelliae 3 parts, Cortex Magnoliae Officinalis 26 parts, Semen Canavaliae 35 parts, Semen Sinapis Albae 25 parts, Rhizoma Cyperi 18 parts, Rhizoma Curcumae 30 parts, Herba Mimosae Pudicae 3 parts, Radix osterici citriodori (Radix Angelicae Citriodorae) 12 parts, Caulis Seu Radix Kadsurae Oblongifoliae 36 parts, Radix seu Folium Rubi Cochinchinensis 25 parts, Radix Et Rhizoma Nardostachyos 11 parts, Caulis Hederae Sinensis 20 parts, Semen Raphani 31 parts and Semen Arecae 16 parts.

5. the pharmaceutical composition of the treatment infantile hernia according to any one of claim 1-4, is characterized in that, described pharmaceutical composition also comprises: Herba veronicae, Flos Campsis, Fructus Bruceae, Radix Aristolochiae and Herba Kalimeridis.

6. the pharmaceutical composition of the treatment infantile hernia according to any one of claim 1-5, it is characterized in that, in described pharmaceutical composition, the ratio of weight and number of each raw medicinal material is: Radix Aconiti Vaginati 15-35 part, Caulis Akebiae 10-20 part, Radix Achyranthis 14-32 part, Caulis Sargentodoxae 18-37 part, Rhizoma Sparganii 13-27 part, Radix berchemiae lineatae 15-40 part, Rhizoma Chuanxiong 11-31 part, Rhizoma Acori Calami 15-25 part, Pumex 13-32 part, Fructus Pruni persicae immaturus 2-3 part, Rhizoma Dioscoreae Bulbiferae 12-22 part, Pyritum 14-36 part, Parmelia saxatilis Ach. 11-21 part, Rhizoma Pinelliae 2-3 part, Cortex Magnoliae Officinalis 16-38 part, Semen Canavaliae 18-42 part, Semen Sinapis Albae 13-33 part, Rhizoma Cyperi 14-28 part, Rhizoma Curcumae 10-30 part, Herba Mimosae Pudicae 3-5 part, Radix osterici citriodori (Radix Angelicae Citriodorae) 12-24 part, Caulis Seu Radix Kadsurae Oblongifoliae 17-36 part, Radix seu Folium Rubi Cochinchinensis 15-25 part, Radix Et Rhizoma Nardostachyos 11-33 part, Caulis Hederae Sinensis 16-28 part, Semen Raphani 11-31 part, Semen Arecae 14-24 part, Herba veronicae 13-35 part, Flos Campsis 10-20 part, Fructus Bruceae 3-5 part, Radix Aristolochiae 1-2 part and Herba Kalimeridis 15-38 part.

7. the pharmaceutical composition of the treatment infantile hernia according to any one of claim 1-6, it is characterized in that, in described pharmaceutical composition, the ratio of weight and number of each raw medicinal material is: Radix Aconiti Vaginati 20 parts, Caulis Akebiae 15 parts, Radix Achyranthis 32 parts, Caulis Sargentodoxae 28 parts, Rhizoma Sparganii 24 parts, Radix berchemiae lineatae 40 parts, Rhizoma Chuanxiong 31 parts, Rhizoma Acori Calami 16 parts, Pumex 32 parts, Fructus Pruni persicae immaturus 2 parts, Rhizoma Dioscoreae Bulbiferae 21 parts, Pyritum 36 parts, Parmelia saxatilis Ach. 14 parts, the Rhizoma Pinelliae 2 parts, Cortex Magnoliae Officinalis 38 parts, Semen Canavaliae 42 parts, Semen Sinapis Albae 33 parts, Rhizoma Cyperi 28 parts, Rhizoma Curcumae 16 parts, Herba Mimosae Pudicae 3 parts, Radix osterici citriodori (Radix Angelicae Citriodorae) 22 parts, Caulis Seu Radix Kadsurae Oblongifoliae 36 parts, Radix seu Folium Rubi Cochinchinensis 25 parts, Radix Et Rhizoma Nardostachyos 33 parts, Caulis Hederae Sinensis 22 parts, Semen Raphani 30 parts, Semen Arecae 20 parts, Herba veronicae 35 parts, Flos Campsis 12 parts, Fructus Bruceae 3 parts, Radix Aristolochiae 2 parts and Herba Kalimeridis 38 parts.

8. the preparation method of the pharmaceutical composition of the treatment infantile hernia according to any one of claim 1-7, is characterized in that, when the dosage form of described pharmaceutical composition is honey refining pill, its preparation method comprises the following steps:

9. the preparation method of the pharmaceutical composition of the treatment infantile hernia according to any one of claim 1-7, is characterized in that, when the dosage form of described pharmaceutical composition is capsule, its preparation method comprises the following steps:

10. the preparation method of the pharmaceutical composition of the treatment infantile hernia according to any one of claim 1-7, is characterized in that, when the dosage form of described pharmaceutical composition is decoction, its preparation method comprises the following steps: