CN105102111B - 用于存储和运送的2d低液面混合袋 - Google Patents
用于存储和运送的2d低液面混合袋 Download PDFInfo
- Publication number
 - CN105102111B CN105102111B CN201380062604.2A CN201380062604A CN105102111B CN 105102111 B CN105102111 B CN 105102111B CN 201380062604 A CN201380062604 A CN 201380062604A CN 105102111 B CN105102111 B CN 105102111B
 - Authority
 - CN
 - China
 - Prior art keywords
 - container
 - mixed zone
 - impeller assembly
 - bag
 - mixed
 - Prior art date
 - Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
 - Active
 
Links
- 239000007788 liquid Substances 0.000 title abstract description 29
 - 239000012530 fluid Substances 0.000 claims abstract description 24
 - 239000004615 ingredient Substances 0.000 claims abstract description 21
 - 238000002156 mixing Methods 0.000 claims abstract description 20
 - 238000007789 sealing Methods 0.000 claims description 20
 - 239000000463 material Substances 0.000 claims description 15
 - 230000000712 assembly Effects 0.000 claims description 11
 - 238000000429 assembly Methods 0.000 claims description 11
 - 238000004891 communication Methods 0.000 claims description 11
 - 238000000034 method Methods 0.000 claims description 7
 - 238000003756 stirring Methods 0.000 claims description 2
 - 230000015572 biosynthetic process Effects 0.000 abstract description 2
 - 239000004698 Polyethylene Substances 0.000 description 6
 - -1 for example Substances 0.000 description 6
 - 229920000642 polymer Polymers 0.000 description 6
 - 229920000573 polyethylene Polymers 0.000 description 5
 - 239000010410 layer Substances 0.000 description 4
 - 229920003023 plastic Polymers 0.000 description 4
 - 239000004033 plastic Substances 0.000 description 4
 - 230000032258 transport Effects 0.000 description 4
 - 159000000013 aluminium salts Chemical class 0.000 description 3
 - 229910000329 aluminium sulfate Inorganic materials 0.000 description 3
 - 238000010586 diagram Methods 0.000 description 3
 - 239000005038 ethylene vinyl acetate Substances 0.000 description 3
 - 239000007789 gas Substances 0.000 description 3
 - 238000002347 injection Methods 0.000 description 3
 - 239000007924 injection Substances 0.000 description 3
 - 239000000203 mixture Substances 0.000 description 3
 - 229920001200 poly(ethylene-vinyl acetate) Polymers 0.000 description 3
 - 230000001681 protective effect Effects 0.000 description 3
 - 239000007787 solid Substances 0.000 description 3
 - 229960005486 vaccine Drugs 0.000 description 3
 - 238000003466 welding Methods 0.000 description 3
 - 229920000219 Ethylene vinyl alcohol Polymers 0.000 description 2
 - 238000013019 agitation Methods 0.000 description 2
 - 238000009295 crossflow filtration Methods 0.000 description 2
 - 238000009826 distribution Methods 0.000 description 2
 - 230000000694 effects Effects 0.000 description 2
 - UFRKOOWSQGXVKV-UHFFFAOYSA-N ethene;ethenol Chemical compound C=C.OC=C UFRKOOWSQGXVKV-UHFFFAOYSA-N 0.000 description 2
 - 239000004715 ethylene vinyl alcohol Substances 0.000 description 2
 - 238000001125 extrusion Methods 0.000 description 2
 - 230000005251 gamma ray Effects 0.000 description 2
 - NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical compound C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 description 2
 - 229920005606 polypropylene copolymer Polymers 0.000 description 2
 - 238000004064 recycling Methods 0.000 description 2
 - 239000012815 thermoplastic material Substances 0.000 description 2
 - QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 1
 - VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 description 1
 - 239000005977 Ethylene Substances 0.000 description 1
 - IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 1
 - 239000004743 Polypropylene Substances 0.000 description 1
 - 229910000831 Steel Inorganic materials 0.000 description 1
 - 239000004699 Ultra-high molecular weight polyethylene Substances 0.000 description 1
 - 229960000583 acetic acid Drugs 0.000 description 1
 - 239000000853 adhesive Substances 0.000 description 1
 - 230000001070 adhesive effect Effects 0.000 description 1
 - 239000002671 adjuvant Substances 0.000 description 1
 - QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
 - DQXBYHZEEUGOBF-UHFFFAOYSA-N but-3-enoic acid;ethene Chemical compound C=C.OC(=O)CC=C DQXBYHZEEUGOBF-UHFFFAOYSA-N 0.000 description 1
 - 210000004027 cell Anatomy 0.000 description 1
 - 210000003040 circulating cell Anatomy 0.000 description 1
 - 239000012611 container material Substances 0.000 description 1
 - 238000005520 cutting process Methods 0.000 description 1
 - 230000000249 desinfective effect Effects 0.000 description 1
 - 238000005553 drilling Methods 0.000 description 1
 - 238000005516 engineering process Methods 0.000 description 1
 - 239000003344 environmental pollutant Substances 0.000 description 1
 - 239000000945 filler Substances 0.000 description 1
 - 238000011049 filling Methods 0.000 description 1
 - 230000009969 flowable effect Effects 0.000 description 1
 - 239000006260 foam Substances 0.000 description 1
 - 230000004927 fusion Effects 0.000 description 1
 - 230000028993 immune response Effects 0.000 description 1
 - 230000001771 impaired effect Effects 0.000 description 1
 - 230000002452 interceptive effect Effects 0.000 description 1
 - 229920001684 low density polyethylene Polymers 0.000 description 1
 - 239000004702 low-density polyethylene Substances 0.000 description 1
 - 238000004519 manufacturing process Methods 0.000 description 1
 - 229920001179 medium density polyethylene Polymers 0.000 description 1
 - 239000004701 medium-density polyethylene Substances 0.000 description 1
 - 239000000155 melt Substances 0.000 description 1
 - 238000012544 monitoring process Methods 0.000 description 1
 - 229940031348 multivalent vaccine Drugs 0.000 description 1
 - 239000001301 oxygen Substances 0.000 description 1
 - 229910052760 oxygen Inorganic materials 0.000 description 1
 - 230000002093 peripheral effect Effects 0.000 description 1
 - 231100000719 pollutant Toxicity 0.000 description 1
 - 229920001155 polypropylene Polymers 0.000 description 1
 - 239000004800 polyvinyl chloride Substances 0.000 description 1
 - 238000001556 precipitation Methods 0.000 description 1
 - 230000001012 protector Effects 0.000 description 1
 - 102000004169 proteins and genes Human genes 0.000 description 1
 - 108090000623 proteins and genes Proteins 0.000 description 1
 - 230000005855 radiation Effects 0.000 description 1
 - 230000001105 regulatory effect Effects 0.000 description 1
 - 238000007665 sagging Methods 0.000 description 1
 - 230000035945 sensitivity Effects 0.000 description 1
 - 238000004088 simulation Methods 0.000 description 1
 - 239000002356 single layer Substances 0.000 description 1
 - 239000010959 steel Substances 0.000 description 1
 - 238000003860 storage Methods 0.000 description 1
 - 229920000785 ultra high molecular weight polyethylene Polymers 0.000 description 1
 
Classifications
- 
        
- C—CHEMISTRY; METALLURGY
 - C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
 - C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
 - C12M23/00—Constructional details, e.g. recesses, hinges
 - C12M23/02—Form or structure of the vessel
 - C12M23/14—Bags
 
 - 
        
- B—PERFORMING OPERATIONS; TRANSPORTING
 - B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
 - B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
 - B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
 - B01F27/05—Stirrers
 - B01F27/11—Stirrers characterised by the configuration of the stirrers
 - B01F27/111—Centrifugal stirrers, i.e. stirrers with radial outlets; Stirrers of the turbine type, e.g. with means to guide the flow
 
 - 
        
- B—PERFORMING OPERATIONS; TRANSPORTING
 - B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
 - B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
 - B01F33/00—Other mixers; Mixing plants; Combinations of mixers
 - B01F33/45—Magnetic mixers; Mixers with magnetically driven stirrers
 - B01F33/453—Magnetic mixers; Mixers with magnetically driven stirrers using supported or suspended stirring elements
 
 - 
        
- B—PERFORMING OPERATIONS; TRANSPORTING
 - B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
 - B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
 - B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
 - B01F35/30—Driving arrangements; Transmissions; Couplings; Brakes
 - B01F35/32—Driving arrangements
 - B01F35/32005—Type of drive
 
 - 
        
- B—PERFORMING OPERATIONS; TRANSPORTING
 - B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
 - B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
 - B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
 - B01F35/50—Mixing receptacles
 - B01F35/513—Flexible receptacles, e.g. bags supported by rigid containers
 
 - 
        
- C—CHEMISTRY; METALLURGY
 - C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
 - C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
 - C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
 - C12M27/02—Stirrer or mobile mixing elements
 
 - 
        
- B—PERFORMING OPERATIONS; TRANSPORTING
 - B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
 - B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
 - B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
 - B01F2101/2202—Mixing compositions or mixers in the medical or veterinary field
 
 - 
        
- B—PERFORMING OPERATIONS; TRANSPORTING
 - B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
 - B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
 - B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
 - B01F2101/44—Mixing of ingredients for microbiology, enzymology, in vitro culture or genetic manipulation
 
 
Landscapes
- Chemical & Material Sciences (AREA)
 - Health & Medical Sciences (AREA)
 - Zoology (AREA)
 - Wood Science & Technology (AREA)
 - Life Sciences & Earth Sciences (AREA)
 - Engineering & Computer Science (AREA)
 - Bioinformatics & Cheminformatics (AREA)
 - Organic Chemistry (AREA)
 - Chemical Kinetics & Catalysis (AREA)
 - Sustainable Development (AREA)
 - Genetics & Genomics (AREA)
 - General Engineering & Computer Science (AREA)
 - Biomedical Technology (AREA)
 - Biotechnology (AREA)
 - Microbiology (AREA)
 - General Health & Medical Sciences (AREA)
 - Biochemistry (AREA)
 - Clinical Laboratory Science (AREA)
 - Mixers Of The Rotary Stirring Type (AREA)
 - Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)
 - Package Specialized In Special Use (AREA)
 - Accessories For Mixers (AREA)
 - Bag Frames (AREA)
 - Packages (AREA)
 - Food-Manufacturing Devices (AREA)
 
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title | 
|---|---|---|---|
| US201261731129P | 2012-11-29 | 2012-11-29 | |
| US61/731129 | 2012-11-29 | ||
| PCT/US2013/068375 WO2014085035A2 (en) | 2012-11-29 | 2013-11-05 | 2d low level mixing bag for storage and shipping | 
Publications (2)
| Publication Number | Publication Date | 
|---|---|
| CN105102111A CN105102111A (zh) | 2015-11-25 | 
| CN105102111B true CN105102111B (zh) | 2018-11-02 | 
Family
ID=50828582
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date | 
|---|---|---|---|
| CN201380062604.2A Active CN105102111B (zh) | 2012-11-29 | 2013-11-05 | 用于存储和运送的2d低液面混合袋 | 
Country Status (8)
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title | 
|---|---|---|---|---|
| EP2925428A4 (en) * | 2012-11-29 | 2016-07-27 | Emd Millipore Corp | CONTAINER WITH MAGNETIC SWIVEL BUCKET ASSEMBLY WITH HOOD | 
| US9827541B1 (en) | 2012-11-29 | 2017-11-28 | Emd Millipore Corporation | 2D low level mixing bag for storage and shipping | 
| CN104269523B (zh) * | 2014-08-29 | 2016-06-29 | 江苏华东锂电技术研究院有限公司 | 粉体烧结系统 | 
| US10323223B2 (en) * | 2016-01-22 | 2019-06-18 | Pbs Biotech, Inc. | Homogeneous cell dispensing mixer | 
| WO2017207822A1 (en) | 2016-06-03 | 2017-12-07 | Lonza Limited | Single use bioreactor | 
| US20180010082A1 (en) * | 2016-06-03 | 2018-01-11 | Lonza Ltd | Bioreactor With Higher Agitation Rates | 
| US11524270B2 (en) | 2018-04-27 | 2022-12-13 | Baxter International Inc. | Method of mixing a pharmaceutical solution and mixing system | 
| US20200148987A1 (en) * | 2018-11-13 | 2020-05-14 | Ge Healthcare Bio-Sciences Corp. | Apparatus, system and method for bioprocessing | 
| US20210402359A1 (en) * | 2020-06-24 | 2021-12-30 | Fresenius Medical Care Holdings, Inc. | Turbulent flow mixing bag and related systems and methods | 
| JP2024535808A (ja) | 2021-09-15 | 2024-10-02 | サニシュア インコーポレイテッド | 低容量磁気混合システム | 
| US12233386B2 (en) | 2021-10-06 | 2025-02-25 | Cytiva Us Llc | Impeller guard | 
| USD1066728S1 (en) * | 2022-09-30 | 2025-03-11 | Maxcyte, Inc. | Bag used for sample or collection | 
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title | 
|---|---|---|---|---|
| JPS636037Y2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1980-04-24 | 1988-02-19 | ||
| GB2202549A (en) * | 1987-03-20 | 1988-09-28 | Philip John Whitney | Foldable fermenter | 
| JPH0730124Y2 (ja) * | 1993-06-22 | 1995-07-12 | 株式会社ニシワキ | 薬液攪拌機 | 
| AU2002362448A1 (en) | 2001-10-03 | 2003-04-14 | Levtech, Inc. | Mixing bag or vessel having a receiver for a fluid-agitating element | 
| US20030227817A1 (en) * | 2002-04-11 | 2003-12-11 | Mobius Technologies, Inc., A California Corporation | Mixer | 
| JP2004149153A (ja) * | 2002-10-30 | 2004-05-27 | Fujimori Kogyo Co Ltd | サーバー、液体サーバー装置およびサーバーへの内袋取付方法 | 
| US7153021B2 (en) | 2003-03-28 | 2006-12-26 | Hyclone Laboratories, Inc. | Container systems for mixing fluids with a magnetic stir bar | 
| US7377686B2 (en) | 2003-09-04 | 2008-05-27 | Millipore Corporation | Disposable mixing system | 
| BRPI0510291A (pt) | 2004-04-27 | 2007-10-30 | Baxter Int | sistema de reator com tanque agitado | 
| US7879599B2 (en) | 2005-04-22 | 2011-02-01 | Hyclone Laboratories, Inc. | Tube ports and related container systems | 
| SE531572C2 (sv) * | 2006-04-05 | 2009-05-26 | Millipore Ab | Engångsenhet för processa produkter | 
| WO2008101124A1 (en) * | 2007-02-15 | 2008-08-21 | Broadley-James Corporation | Sterile bioreactor bag with integrated drive unit | 
| WO2009014737A1 (en) | 2007-07-25 | 2009-01-29 | Abbott Laboratories | Magnetic mixer | 
| US9044718B2 (en) | 2008-03-19 | 2015-06-02 | Sartorius Stedim Biotech Gmbh | Mixing vessel | 
| FR2933881B1 (fr) | 2008-07-16 | 2011-05-27 | Sartorius Stedim Biotech Sa | Melange dans un conteneur d'un contenu ayant un composant de base et un composant a melanger | 
| FR2952041B1 (fr) | 2009-10-29 | 2012-02-03 | Sartorius Stedim Biotech Sa | Film multicouche de paroi de poche a soudures destinee a un produit biopharmaceutique. | 
| JP2011131908A (ja) * | 2009-12-24 | 2011-07-07 | Duskin Co Ltd | 液体バッグ及び液体供給サーバー | 
| JP5584317B2 (ja) * | 2010-03-09 | 2014-09-03 | イー・エム・デイー・ミリポア・コーポレイシヨン | センサ付きプロセスバッグ容器 | 
| SG10201504574RA (en) | 2010-07-30 | 2015-07-30 | Emd Millipore Corp | Plastic bag containing a disposable vortex breaker | 
| JP5751856B2 (ja) | 2011-02-18 | 2015-07-22 | 株式会社日立製作所 | 生体細胞の培養容器、及び培養装置 | 
| EP3603787A1 (en) * | 2012-04-18 | 2020-02-05 | Life Technologies Corporation | Methods and apparatus for gas stream mass transfer with a liquid | 
- 
        2013
        
- 2013-11-05 SG SG10201800529YA patent/SG10201800529YA/en unknown
 - 2013-11-05 ES ES13858238T patent/ES2848026T3/es active Active
 - 2013-11-05 US US14/440,376 patent/US9744507B2/en active Active
 - 2013-11-05 SG SG10201708995SA patent/SG10201708995SA/en unknown
 - 2013-11-05 JP JP2015545054A patent/JP6503299B2/ja active Active
 - 2013-11-05 WO PCT/US2013/068375 patent/WO2014085035A2/en active Application Filing
 - 2013-11-05 CN CN201380062604.2A patent/CN105102111B/zh active Active
 - 2013-11-05 IN IN4298DEN2015 patent/IN2015DN04298A/en unknown
 - 2013-11-05 SG SG11201503669XA patent/SG11201503669XA/en unknown
 - 2013-11-05 EP EP13858238.2A patent/EP2925427B1/en active Active
 
 
Also Published As
| Publication number | Publication date | 
|---|---|
| ES2848026T3 (es) | 2021-08-05 | 
| SG11201503669XA (en) | 2015-06-29 | 
| EP2925427A4 (en) | 2016-08-17 | 
| WO2014085035A3 (en) | 2015-07-16 | 
| SG10201708995SA (en) | 2017-11-29 | 
| EP2925427B1 (en) | 2020-12-23 | 
| EP2925427A2 (en) | 2015-10-07 | 
| IN2015DN04298A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 2015-10-16 | 
| CN105102111A (zh) | 2015-11-25 | 
| US20150258513A1 (en) | 2015-09-17 | 
| JP6503299B2 (ja) | 2019-04-17 | 
| JP2015536884A (ja) | 2015-12-24 | 
| SG10201800529YA (en) | 2018-02-27 | 
| WO2014085035A2 (en) | 2014-06-05 | 
| US9744507B2 (en) | 2017-08-29 | 
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Legal Events
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|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |