CN105031406A - Anticancer traditional Chinese medicine preparation - Google Patents

Anticancer traditional Chinese medicine preparation Download PDF

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CN105031406A
CN105031406A CN201510535746.7A CN201510535746A CN105031406A CN 105031406 A CN105031406 A CN 105031406A CN 201510535746 A CN201510535746 A CN 201510535746A CN 105031406 A CN105031406 A CN 105031406A
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陈丽
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Abstract

The invention discloses an anticancer traditional Chinese medicine preparation. The anticancer traditional Chinese medicine preparation is prepared from the following raw materials in parts by weight: 1-5 parts of oldenlandia diffusa, 1-5 parts of ganoderma lucidum, 10-20 parts of American ginseng, 1-5 parts of salviae miltiorrhizae, 1-5 parts of peach kernels, 10-20 parts of semen coicis, 1-5 parts of fennel, 1-5 parts of costustoot, 1-5 parts of szechwan chinaberry fruit, 10-20 parts of dark plums, 5-10 parts of radix bupleuri, 5-10 parts of albizia julibrissin, 5-10 parts of selfheal, 5-10 parts of perilla leaf, 1-5 parts of white peony roots, 1-5 parts of campsis grandiflora, 1-5 parts of dahurian patrinia herb, 1-5 parts of dry gecko, 1-5 parts of trogopterus dung, 1-5 parts of olibanum and 1-5 parts of gamboge. The anticancer traditional Chinese medicine preparation has the effects of well inhibiting tumor cell growth and promoting tumor cell apoptosis, has a strong killing effect on a plurality of tumor cells and is wide in application range; and the experiment result shows that the traditional Chinese medicine composition disclosed by the invention is safe to use, and free of toxic or side effect after being used for a long period of time.

Description

A kind of anticancer Chinese medicine preparation
Technical field
The present invention relates to the field of Chinese medicines, specifically a kind of anticancer Chinese medicine preparation.
Background technology
Malignant tumor has become common and serious threat human life and quality of life principal disease.Claim in " report of world's tumor " that World Health Organization (WHO) delivers in April, 2004, a few years from now on will be the global tumor time occurred frequently, and sickness rate will increase by 50%, increase by 1,500 ten thousand cases every year to the year two thousand twenty.
Tumor incidence and mortality rate rise year by year, serious threat human health, have become the one of the main reasons of human death.At present, mostly the inoperable tumor of doctor trained in Western medicine is based on chemotherapy and radiation, but antineoplastic chemotherapy medicine and radiotherapy have serious side reaction, easily causes bone marrow hematogenesis obstacle, gastrointestinal reaction and constitutional secondary tumor etc.And Chinese medicine is in treatment tumor, relative chemotherapy and radiotherapy side effect less, and the damage that can cause anti-tumor chemotherapeutic and radiotherapy, improves the immune indexes of tumor patient.Therefore, the Chinese medicine of development treatment tumor, in oncotherapy, drug combination becomes trend.
Summary of the invention
The object of the present invention is to provide a kind of good inhibition tumor cell growth and the anticancer Chinese medicine preparation that can promote the effect of apoptosis of tumor cells, to solve the problem proposed in above-mentioned background technology.
For achieving the above object, the invention provides following technical scheme:
An anticancer Chinese medicine preparation, is made up of the following raw material according to weight portion: Agkistrodon gives up careless 1-5 part, Ganoderma 1-5 part, Radix Panacis Quinquefolii 10-20 part, Radix Salviae Miltiorrhizae 1-5 part, Semen Persicae 1-5 part, Semen Coicis 10-20 part, Fructus Foeniculi 1-5 part, Radix Aucklandiae 1-5 part, Fructus Toosendan 1-5 part, Fructus Mume 10-20 part, Radix Bupleuri 5-10 part, Flos Albiziae 5-10 part, Spica Prunellae 5-10 part, Folium Perillae 5-10 part, Radix Paeoniae Alba 1-5 part, Flos Campsis 1-5 part, Herba Patriniae 1-5 part, Gekko Swinhonis Gekko Swinhonis 1-5 part, Oletum Trogopterori 1-5 part, Olibanum 1-5 part, Resina garciniae 1-5 part.
As the further scheme of the present invention: described anticancer Chinese medicine preparation, be made up of the following raw material according to weight portion: Agkistrodon gives up careless 2-4 part, Ganoderma 2-4 part, Radix Panacis Quinquefolii 13-17 part, Radix Salviae Miltiorrhizae 2-4 part, Semen Persicae 2-4 part, Semen Coicis 13-17 part, Fructus Foeniculi 2-4 part, Radix Aucklandiae 2-4 part, Fructus Toosendan 2-4 part, Fructus Mume 13-17 part, Radix Bupleuri 7-9 part, Flos Albiziae 7-9 part, Spica Prunellae 7-9 part, Folium Perillae 7-9 part, Radix Paeoniae Alba 2-4 part, Flos Campsis 2-4 part, Herba Patriniae 2-4 part, Gekko Swinhonis Gekko Swinhonis 2-4 part, Oletum Trogopterori 2-4 part, Olibanum 2-4 part, Resina garciniae 2-4 part.
As the further scheme of the present invention: described anticancer Chinese medicine preparation, be made up of the following raw material according to weight portion: Agkistrodon house grass 3 parts, Ganoderma 3 parts, Radix Panacis Quinquefolii 15 parts, Radix Salviae Miltiorrhizae 3 parts, 3 parts, Semen Persicae, Semen Coicis 15 parts, Fructus Foeniculi 3 parts, the Radix Aucklandiae 3 parts, Fructus Toosendan 3 parts, Fructus Mume 15 parts, Radix Bupleuri 8 parts, Flos Albiziae 8 parts, Spica Prunellae 8 parts, Folium Perillae 8 parts, the Radix Paeoniae Alba 3 parts, Flos Campsis 3 parts, Herba Patriniae 3 parts, Gekko Swinhonis Gekko Swinhonis 3 parts, Oletum Trogopterori 3 parts, Olibanum 3 parts, Resina garciniae 3 parts.
The mechanism of action of each raw material in the present invention:
Agkistrodon house grass is pungent, sweet, hot greatly.Return kidney, spleen, the heart, Liver Channel.Mend fire supporing yang, let the fire back to its origin, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow.
Ganoderma acrid in the mouth, warm in nature, return spleen, kidney channel.Have warming spleen and stopping diarrha, take the photograph saliva, warming the kidney, effect of controlling nocturnal emission with astringent drugs reducing urination.
Radix Panacis Quinquefolii sweet in the mouth, slightly warm in nature.Return lung, spleen channel.There is invigorating QI to consolidate the body surface resistance, diuresis, expelling pus and toxin by strengthening QI, the functions such as granulation promoting.
Radix Salviae Miltiorrhizae, Semen Persicae, blood stasis dispelling swings long-pending, then blood stasis is dispelled, and fresh blood is raw, has greatly the wonderful of qi and blood tonifying.
Semen Coicis, has spleen invigoratingeliminating dampness by diuresis, eliminating impediment antidiarrheal.For edema, beriberi, dysuria, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleeneffect.
Fructus Toosendan is bitter, cold; Slightly poisonous.Return liver, small intestinal, urinary bladder channel.There is soothing liver-QI, promoting the circulation of QI to relieve pain, the effects such as anthelmintic.
Fructus Foeniculi acrid in the mouth, warm in nature.Return liver,kidney,spleen, stomach warp.There is dispersing cold for relieving pain, the function of regulating qi-flowing for harmonizing stomach.
The Radix Aucklandiae is pungent, bitter, temperature.Return spleen, stomach, large intestine, three burnt, gallbladder meridians.There is effect of promoting the circulation of QI to relieve pain, invigorating the spleen and regulating the stomach.
Fructus Mume sour in the mouth, puckery, warm in nature.Return liver, spleen, lung, large intestine channel.The effect of there is astringing the lung, promoting the production of body fluid.Can supplement the loss of body fluid, four Chinese medicine is adjuvant altogether in side.
Radix Panacis Quinquefolii, can invigorating QI to consolidate the body surface resistance based on tonify deficiency, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Cave in for insufficiency of vital energy and blood, skin infection, difficulty in discharging of pus or burst for a long time and do not hold back person.Radix Panacis Quinquefolii has the function of good promoting pus discharge and tissue regeneration strengthening, i.e. the abscess suppuration granulation promoting of disunion for a long time.Modern medicine study shows, Radix Panacis Quinquefolii includes and multiple antibiotic effective ingredient, and the immunologic function of energy enhancing body, therefore can also be used for the generation preventing some infectious disease." book on Chinese herbal medicine meets former " carries: " all void of Radix Panacis Quinquefolii energy tonifying five ZANG-organs, controls stringy pulse spontaneous perspiration, rush down YIN-fire, remove lung-heat, lossless, sends out, and has antiperspirant then to stop." be the good medicine promoting resistance and defence disease.
Radix Bupleuri is bitter, is slightly cold.Return liver, gallbladder meridian.Function reconciling superficies and interior, soothing the liver, yang invigorating, for depression of liver-QI, the pain over the hypochondriac region, menoxenia etc." Yaoxing Fu " carries: bitter in the mouth, flat, and feeble QI is trembled with fear, nontoxic.Rise also, the yang aspect of yin also.It is with having four: pain over the hypochondrium is close in left and right two, and afternoon fever is toward next life.Main blood in dirty regulating menstruation, the main gas of flesh is passed through.The few positive the exterior and the interior four of brothers through medicine also.
Flos Albiziae property is put down, sweet in the mouth.Function resolving stagnation for tranquilization.For irritability, melancholy insomnia.There is the function of resolving stagnation for tranquilization, promoting blood circulation and detumescence; For irritability, melancholy is had a sleepless night, lung abscess skin ulcer is swollen, traumatic pain, and leaf is containing tannin, quercitrin.Flos Albiziae contains Herba Albiziae glycoside, tannin, resolving stagnation for tranquilization, appetizing of regulating the flow of vital energy, activating collaterals to relieve pain, for irritability, melancholy insomnia.Control pent-up uncomfortable in chest, insomnia, forgetful, acute conjunctivitis, can settling five organs, and will, improving healthy complexion, have keep fit preferably, calm, the effect of calming the nerves, improve looks, be also treat neurasthenic good merchantable brand.
Spica Prunellae bitter, acrid, cold.Multiplex come mass dissipating and swelling eliminating, control scrofula, goiter, acute mastitis swell and ache." Bencao Congxin " carries it: control scrofula, scrofula, goiter, disease heavily fortified point, acute mastitis, breast carcinoma.Spica Prunellae is the key medicine of clearing away liver-fire, Disperse hepatic depression, the disease of what it cured mainly is mostly Liver Channel.This product is equipped with Flos Chrysanthemi, Semen Cassiae, can liver heat removing and eyesight improving, controls conjunctival congestion and swelling pain, is equipped with Concha Haliotidis, Ramulus Uncariae Cum Uncis, can pancake liver-yang, controls headache, dizzy; Be equipped with the product such as Radix Scrophulariae, Bulbus Fritillariae Uninbracteatae, Concha Ostreae, can hard masses softening and resolving, control scrofula and go through tuberculosis.In recent years clinically again for tumor.
Folium Perillae property and flavor of peppery and warm, have deliver, cold expelling, the effect of regulating the flow of vital energy and seeking.Cure cold wind and cold, fever with aversion to cold, cough, asthma, distension and fullness of the chest and abdomen etc.Compendium of Material Medica is carried " promoting the circulation of QI to alleviate the stagnation in middle-JIAO, clearing away phlegm profit lung, and blood, warming middle-JIAO, pain relieving, Dingchuan, antiabortive ".
The Radix Paeoniae Alba enters liver, spleen channel, nourishing blood to suppress the hyperactive liver, pain relieving in slow, and yin fluid astringing receives antiperspirant.Control the breast abdomen pain over the hypochondriac region, dysentery is suffered from abdominal pain, and spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia, married woman's blood closes obstructed, repercussive blood, can lose pus, beneficial woman's blood." Japan hanako materia medica ": control wind, mend labor, all diseases of main woman, and antenatal rear all diseases, Tong Yueshui, brings down a fever, relieving restlessness, QI invigorating, the capable hot disease in sky, pestilence miasma, mania and irritation, and married woman's blood is transported, and hemorrhoidal hamorrhage, rushes down blood, hemorrhoid complicated by anal fistula.Carbuncle on the back, skin ulcer scabies, headache, improving eyesight, conjunctival congestion exerts meat.The many QI invigorating of redness of the skin or complexion person, white person controls blood.
Gekko Swinhonis goes the dry products of internal organs to enter Chinese medicine, and name " Gekko Swinhonis Gekko Swinhonis ", has tonifying the lung kidney, benefiting essence-blood, relieving cough and relieving asthma, spasmolytic to dispel the wind and disperse effect of detumescence, can control lymphoid tuberculosis, neuralgia, chronic arthritis, lump in breast.Taste becomes, cold.Slightly poisonous.Cure mainly and dispel the wind, active, eliminating stagnation.For paralysis due to windstroke, rheumatic arthritis, osteomyelitis, tuberculous lymphadenitis, tumor.The good medicine for the treatment of breast tumor.
Oletum Trogopterori is the feces of Mammalia, flying squirrel section animal trogopterus xanthipes Milne-Edwards (cold number bird), flying squirrel or other nearly edge animal.Oletum Trogopterori is sweet in flavor and warm in property, nontoxic, enters Liver Channel, has dredging blood vessel, effect of eliminating stasis to stop pain; It is gynecological's key medicine.Cure mainly stasis, amenorrhea, stomachache; Disease such as the breast side of body twinge tumbling and swelling and snake bite and insect sting etc.It is logical that Oletum Trogopterori hardship lets out temperature, and " tonneau gaseous pulse ", " general rule is not bitterly." therefore " Bencao Jingshu " calls it, and " stasis passages through which vital energy circulates, gas must not be gone, and attacks the cards such as sharp pain, must use." " detailed outline " year: Oletum Trogopterori, also, abnormal smells from the patient is all thick, the yin aspect of yin, therefore enters blood system for liver channel of foot-Jueyin medicine.The main blood of liver, so medicine can control disorders of blood, loose blood and blood and only all pains.Only except malaria dysentery, removing food stagnancy reduces phlegm, and treats infantile malnutrition parasite killing, controls arthralgia due to stagnation of blood, all diseases of blood eye, all belongs to Liver Channel also.
Olibanum regulating QI, invigorates blood circulation, and pain relieving chases after poison, controls coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge.Supplement to the Herbal carries it: " treat deaf, apoplexy locked mouth, married woman's vim and vigour, can send out wine, manage air-cooled, and only large intestine is let out, and treats all skin ulcers and makes internal diabetes.”
Resina garciniae is subsided a swelling, removing toxic substances, hemostasis, parasite killing.Control swollen ulcer drug, stubborn dermatitis malignant boil, bleeding due to trauma, ulcerative gingivitis decayed tooth, burn.Resina garciniae has stronger bacteriostasis to staphylococcus aureus, and alcoholic solution has stronger bacteriostasis to bacillus pyocyaneus.The anti-tumor activity that gamlogic acid is stronger to kinds of tumors display, and toxic and side effects is smaller in effective dosage ranges, very high selectivity is had to the suppression of tumor cell, optionally can kill cancerous cell, and intact animal's hemopoietic system and immunologic function are not affected, this is not available for current tumor chemotherapeutic drug.Pharmacokinetic also shows, and gamlogic acid has higher distribution and longer persistent period in tumor tissues.Gamlogic acid is broad-spectrum anti-tumor medicine, has significant curative effect to kinds of tumors.
A kind of Chinese medicine material of Flos Campsis, has promoting the circulation of blood blood stasis removing, cooling blood, expelling wind dampness removing, heat-clearing and toxic substances removing, and acrid in the mouth acid, cold nature returns liver, pericardium channel, function promoting blood circulation to remove blood stasis, cooling blood, expelling wind.Cure mainly menoxenia, amenorrhea lump in the abdomen, puerperal swelling of the breast, skin pruritus. " Amplification on Materia Medica addendum ": Flos Campsis, control the key medicine of pain in blood also, and nourishing YIN victory very, is stamped and keeps and walk alone, in married woman side multiplex what." Nanning City's medicine will ": the merit having eliminating inflammation and expelling toxin, hemostasis and pain-relieving, evacuation of pus granulation promoting, controls red Hakuri.
Herba Patriniae nature and flavor hardship is flat, has effect of heat-clearing and toxic substances removing, evacuation of pus removing blood stasis with potent drugs.Acute appendicitis, dysentery, leucorrhea with red and white discharge, the stagnant stomachache of the stasis of blood in puerperal, conjunctival congestion and swelling pain can be cured.Enter stomach, large intestine, Liver Channel.Cure mainly heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, blood circulation promoting competent silt.For acute appendicitis, lung abscess and sore and toxic, the stagnant caused breast abdomen pain of the excess-heat stasis of blood, the diseases such as the stagnant stomachache of the stasis of blood in puerperal.
Compared with prior art, the invention has the beneficial effects as follows:
The present invention has the growth of good inhibition tumor cell and can promote the effect of apoptosis of tumor cells, and to kinds of tumor cells, all there is strong killing action, have wide range of applications, and experimental result shows Chinese medicine composition provided by the invention, use safety, life-time service has no side effect.
Detailed description of the invention
Below in conjunction with the embodiment of the present invention, be clearly and completely described the technical scheme in the embodiment of the present invention, obviously, described embodiment is only the present invention's part embodiment, instead of whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art, not making the every other embodiment obtained under creative work prerequisite, belong to the scope of protection of the invention.
Embodiment 1
In the embodiment of the present invention, an anticancer Chinese medicine preparation, is made up of the following raw material according to weight portion: Agkistrodon house grass 1 part, Ganoderma 1 part, Radix Panacis Quinquefolii 10 parts, Radix Salviae Miltiorrhizae 1 part, 1 part, Semen Persicae, Semen Coicis 10 parts, Fructus Foeniculi 1 part, the Radix Aucklandiae 1 part, Fructus Toosendan 1 part, Fructus Mume 10 parts, Radix Bupleuri 5 parts, Flos Albiziae 5 parts, Spica Prunellae 5 parts, Folium Perillae 5 parts, the Radix Paeoniae Alba 1 part, Flos Campsis 1 part, Herba Patriniae 1 part, Gekko Swinhonis Gekko Swinhonis 1 part, Oletum Trogopterori 1 part, Olibanum 1 part, Resina garciniae 1 part.
Embodiment 2
In the embodiment of the present invention, an anticancer Chinese medicine preparation, is made up of the following raw material according to weight portion: Agkistrodon house grass 5 parts, Ganoderma 5 parts, Radix Panacis Quinquefolii 20 parts, Radix Salviae Miltiorrhizae 5 parts, 5 parts, Semen Persicae, Semen Coicis 20 parts, Fructus Foeniculi 5 parts, the Radix Aucklandiae 5 parts, Fructus Toosendan 5 parts, Fructus Mume 20 parts, Radix Bupleuri 10 parts, Flos Albiziae 10 parts, Spica Prunellae 10 parts, Folium Perillae 10 parts, the Radix Paeoniae Alba 5 parts, Flos Campsis 5 parts, Herba Patriniae 5 parts, Gekko Swinhonis Gekko Swinhonis 5 parts, Oletum Trogopterori 5 parts, Olibanum 5 parts, Resina garciniae 5 parts.
Embodiment 3
In the embodiment of the present invention, an anticancer Chinese medicine preparation, is made up of the following raw material according to weight portion: Agkistrodon house grass 2 parts, Ganoderma 2 parts, Radix Panacis Quinquefolii 13 parts, Radix Salviae Miltiorrhizae 2 parts, 2 parts, Semen Persicae, Semen Coicis 13 parts, Fructus Foeniculi 2 parts, the Radix Aucklandiae 2 parts, Fructus Toosendan 2 parts, Fructus Mume 13 parts, Radix Bupleuri 7 parts, Flos Albiziae 7 parts, Spica Prunellae 7 parts, Folium Perillae 7 parts, the Radix Paeoniae Alba 2 parts, Flos Campsis 2 parts, Herba Patriniae 2 parts, Gekko Swinhonis Gekko Swinhonis 2 parts, Oletum Trogopterori 2 parts, Olibanum 2 parts, Resina garciniae 2 parts.
Embodiment 4
In the embodiment of the present invention, an anticancer Chinese medicine preparation, is made up of the following raw material according to weight portion: Agkistrodon house grass 4 parts, Ganoderma 4 parts, Radix Panacis Quinquefolii 17 parts, Radix Salviae Miltiorrhizae 4 parts, 4 parts, Semen Persicae, Semen Coicis 17 parts, Fructus Foeniculi 4 parts, the Radix Aucklandiae 4 parts, Fructus Toosendan 4 parts, Fructus Mume 17 parts, Radix Bupleuri 9 parts, Flos Albiziae 9 parts, Spica Prunellae 9 parts, Folium Perillae 9 parts, the Radix Paeoniae Alba 4 parts, Flos Campsis 4 parts, Herba Patriniae 4 parts, Gekko Swinhonis Gekko Swinhonis 4 parts, Oletum Trogopterori 4 parts, Olibanum 4 parts, Resina garciniae 4 parts.
Embodiment 5
In the embodiment of the present invention, an anticancer Chinese medicine preparation, is made up of the following raw material according to weight portion: Agkistrodon house grass 3 parts, Ganoderma 3 parts, Radix Panacis Quinquefolii 15 parts, Radix Salviae Miltiorrhizae 3 parts, 3 parts, Semen Persicae, Semen Coicis 15 parts, Fructus Foeniculi 3 parts, the Radix Aucklandiae 3 parts, Fructus Toosendan 3 parts, Fructus Mume 15 parts, Radix Bupleuri 8 parts, Flos Albiziae 8 parts, Spica Prunellae 8 parts, Folium Perillae 8 parts, the Radix Paeoniae Alba 3 parts, Flos Campsis 3 parts, Herba Patriniae 3 parts, Gekko Swinhonis Gekko Swinhonis 3 parts, Oletum Trogopterori 3 parts, Olibanum 3 parts, Resina garciniae 3 parts.
Antitumor pharmacological evaluation
1, anti-tumor in vivo experiment
(1) experiment material
Test medicine: adopt Chinese medicine preparation prepared by the embodiment of the present invention 5.Positive control drug: cyclophosphamide.
(2) experimental technique
Laboratory animal: get Kunming mouse, body weight 18 ~ 22g, male and female dual-purpose.
Get the inoculation lung cancer Lewis tumor block of 10 days, make Lewis cell suspension (cell number 1 × 10 7/ ml), except normal healthy controls group, all the other mice upper limb right axil subcutaneous vaccination lung cancer Lewis cell suspension 0.2ml, inoculate after 24 hours, be divided into the Chinese medicine preparation 15g/kg of normal saline group 20ml/kg, embodiment 5 at random, cyclophosphamide (CTX) positive drug control group 60mg/kg lumbar injection.Each group of equal successive administration 14 days, put to death whole mice with the 15th day, gets tumor block and weigh, and calculated tumour inhibiting rate.Specific experiment result is as shown in table 1:
Table 1 Chinese medicine preparation is to the inhibitory action of mice lung cancer Lewis
Group Number of animals (only) Dosage (/kg) Tumor heavy (g) Tumour inhibiting rate (%)
Healthy group 20 - - -
Normal saline group 20 20ml 3.70±0.57 -
Cyclophosphamide group 20 60ml 0.68±0.30 ** 81.62
Embodiment 5 20 15g 1.52±0.51 ** 58.92
Note: compare with normal saline group, *p < 0.05; *p < 0.01.
Shown by the experimental result of table 1 anti-tumor in vivo, Traditional Chinese medicine compound composition provided by the invention all effectively can suppress the growth of Mice Bearing Lewis Lung Cancer, and along with the increase of dosage, antitumor action strengthens, and experimental result shows that Traditional Chinese medicine compound composition provided by the invention has stronger effect of anti-lung cancer.
The present invention is according to Chinese medical theory, the theory of determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs is adopted to carry out proportioning prescription, shown by above experimental result, in Chinese medicine preparation body provided by the invention, there is good antitumor action, and to kinds of tumor cells, all there is very strong inhibitory action, illustrate that Chinese medicine preparation provided by the invention may be used for preparing antineoplastic new medicine, and life-time service has no adverse reaction.
Clinical trial
Drug therapy tumor 100 example of the present invention.Wherein pulmonary carcinoma 10 example, hepatocarcinoma 10 example, 30 Cases of Gastric Cancer, intestinal cancer 25 example, cervical cancer 11 example, ovarian cyst 4 example, the cerebral tumor 5 example, the esophageal carcinoma 5 example.Above-mentioned case all can be taken food, and does not occur dyscrasia.Month symptom improver 80 that takes medicine is routine, effective percentage 80%.3 months symptom improvers 92 that take medicine are routine, effective percentage 92%.To take medicine 6 months transference cures, health check-up tumor disappearance person 70 example, cure rate 70%, 12 months tumor disappearance person 88 examples of taking medicine, cure rate 88%.
Case 1
Zhang, man, 57 years old.In October, 2006 is diagnosed as centrality pulmonary carcinoma in Beijing Tumour Hospital, late period, cannot perform the operation.Patient's hemoptysis, chest pain, weak.Look into tongue as minute surface, middle ditch depth, body of the tongue color is dark, and indented tongue margin is many.Two cun of pearl type smooth pulses, Guan Xian, chi string, take the medicine prepared by the embodiment of the present invention 4, after 20 days, hemoptysis number of times by reduce to for 5-6 time every day 3-4 time, chest pain without being clearly better, after 30 days, hemoptysis, chest pain disappear, spirit take a turn for the better.Patient adheres to taking medicine 1 year, period in a medicine other drug, and health is always good.Check to tumour hospital, tumor disappearance.
Case 2
Cai, man, 42 years old, in November, 20013 is all diagnosed as Liver masses at attached institute of Zhengzhou University one B ultrasonic, CT, and (leftlobe of liver had 8.2 × 5.6cm 2low close shade), be hepatocarcinoma doing liver biopsy diagnosis, patient continues abdominal distention, and be interrupted costa sternales pain, upper abdominal pain, upper abdomen tenderness is obvious.Thirsty polydipsia, yellowish fur is thick, and area is large, purplish tongue, two CUN-pulse imaginary number, having a double meaning arteries and veins pearl type, smooth pulse winding up, two chi deficient and stringy pulse.Take the Chinese medicine prepared by the embodiment of the present invention 5, after one month, abdominal distention, pain obviously alleviate, after two months abdominal distention once in a while.In the check B ultrasonic display of Yingyang City institute of traditional Chinese medicine: leftlobe of liver is normal.Continue now to take medicine.
Case 3
Lee, female, 35 years old, in January, 20010 showed at Yingyang City the People's Hospital B ultrasonic: left ovary increases and has little cyst, and chemically examined out serum prolactin (PRL) and increase.Take the medicine prepared by the embodiment of the present invention 4, within one month, rear left abdominal mass disappears, and breast and lower abdomen pain obviously alleviate, and after two months, only left lower abdomen gently aches once in a while, the eumenorrhea, now continues to take medicine.
To those skilled in the art, obviously the invention is not restricted to the details of above-mentioned one exemplary embodiment, and when not deviating from spirit of the present invention or basic feature, the present invention can be realized in other specific forms.Therefore, no matter from which point, all should embodiment be regarded as exemplary, and be nonrestrictive, scope of the present invention is limited by claims instead of above-mentioned explanation, and all changes be therefore intended in the implication of the equivalency by dropping on claim and scope are included in the present invention.
In addition, be to be understood that, although this description is described according to embodiment, but not each embodiment only comprises an independently technical scheme, this narrating mode of description is only for clarity sake, those skilled in the art should by description integrally, and the technical scheme in each embodiment also through appropriately combined, can form other embodiments that it will be appreciated by those skilled in the art that.

Claims (3)

1. an anticancer Chinese medicine preparation, it is characterized in that, be made up of the following raw material according to weight portion: Agkistrodon gives up careless 1-5 part, Ganoderma 1-5 part, Radix Panacis Quinquefolii 10-20 part, Radix Salviae Miltiorrhizae 1-5 part, Semen Persicae 1-5 part, Semen Coicis 10-20 part, Fructus Foeniculi 1-5 part, Radix Aucklandiae 1-5 part, Fructus Toosendan 1-5 part, Fructus Mume 10-20 part, Radix Bupleuri 5-10 part, Flos Albiziae 5-10 part, Spica Prunellae 5-10 part, Folium Perillae 5-10 part, Radix Paeoniae Alba 1-5 part, Flos Campsis 1-5 part, Herba Patriniae 1-5 part, Gekko Swinhonis Gekko Swinhonis 1-5 part, Oletum Trogopterori 1-5 part, Olibanum 1-5 part, Resina garciniae 1-5 part.
2. anticancer Chinese medicine preparation according to claim 1, it is characterized in that, be made up of the following raw material according to weight portion: Agkistrodon gives up careless 2-4 part, Ganoderma 2-4 part, Radix Panacis Quinquefolii 13-17 part, Radix Salviae Miltiorrhizae 2-4 part, Semen Persicae 2-4 part, Semen Coicis 13-17 part, Fructus Foeniculi 2-4 part, Radix Aucklandiae 2-4 part, Fructus Toosendan 2-4 part, Fructus Mume 13-17 part, Radix Bupleuri 7-9 part, Flos Albiziae 7-9 part, Spica Prunellae 7-9 part, Folium Perillae 7-9 part, Radix Paeoniae Alba 2-4 part, Flos Campsis 2-4 part, Herba Patriniae 2-4 part, Gekko Swinhonis Gekko Swinhonis 2-4 part, Oletum Trogopterori 2-4 part, Olibanum 2-4 part, Resina garciniae 2-4 part.
3. anticancer Chinese medicine preparation according to claim 2, it is characterized in that, be made up of the following raw material according to weight portion: Agkistrodon house grass 3 parts, Ganoderma 3 parts, Radix Panacis Quinquefolii 15 parts, Radix Salviae Miltiorrhizae 3 parts, 3 parts, Semen Persicae, Semen Coicis 15 parts, Fructus Foeniculi 3 parts, the Radix Aucklandiae 3 parts, Fructus Toosendan 3 parts, Fructus Mume 15 parts, Radix Bupleuri 8 parts, Flos Albiziae 8 parts, Spica Prunellae 8 parts, Folium Perillae 8 parts, the Radix Paeoniae Alba 3 parts, Flos Campsis 3 parts, Herba Patriniae 3 parts, Gekko Swinhonis Gekko Swinhonis 3 parts, Oletum Trogopterori 3 parts, Olibanum 3 parts, Resina garciniae 3 parts.
CN201510535746.7A 2015-08-28 2015-08-28 Anticancer traditional Chinese medicine preparation Pending CN105031406A (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1559600A (en) * 2004-02-26 2005-01-05 黄国正 Anti-cancer pill
CN1650991A (en) * 2004-12-17 2005-08-10 董运祥 Traditional Chinese medicine for treating tumour and its preparation method
CN101518593A (en) * 2009-03-02 2009-09-02 张之霞 Traditional Chinese medicine composition for curing hyperplasia of mammary glands and resisting tumors and preparation method thereof
CN101766777A (en) * 2009-12-29 2010-07-07 吉林省现代中药研究开发中心 Chinese medicine composite for treating chronic renal failure

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1559600A (en) * 2004-02-26 2005-01-05 黄国正 Anti-cancer pill
CN1650991A (en) * 2004-12-17 2005-08-10 董运祥 Traditional Chinese medicine for treating tumour and its preparation method
CN101518593A (en) * 2009-03-02 2009-09-02 张之霞 Traditional Chinese medicine composition for curing hyperplasia of mammary glands and resisting tumors and preparation method thereof
CN101766777A (en) * 2009-12-29 2010-07-07 吉林省现代中药研究开发中心 Chinese medicine composite for treating chronic renal failure

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
广安门医院肿瘤科: "中西医结合治疗癌症的一些体会", 《中医杂志》 *

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