CN102940808A - Prescription medicine for treating lung cancer and preparation method - Google Patents
Prescription medicine for treating lung cancer and preparation method Download PDFInfo
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Abstract
The invention discloses a prescription medicine for treating lung cancer and a preparation method and belongs to the field of traditional Chinese medicine. The prescription medicine comprises the following active ingredients in parts by weight: 70-100 parts of radix rehmanniae, 60-85 parts of holly leaf, 55-75 parts of radix ophiopogonis, 50-70 parts of cortex lycii radicis, 45-65 parts of dangshen, 40-55 parts of cordate houttuynia, 35-50 parts of astragalus root, 32-46 parts of sculellaria barbata, 28-40 parts of poria cocos, 22-36 parts of lalang grass rhizome, 18-30 parts of bighead atractylodes rhizome, 15-25 parts of folium cycas, 12-20 parts of tendril-leaved fritillary bulb, 8-16 parts of rhizoma bistortae, 5-15 parts of almond and 3-12 parts of roasted centipede. According to the invention, the materials are precisely selected, the prescription medicine is reasonably prepared by traditional Chinese medicinal materials having the functions of invigorating spleen and replenishing qi, nourishing Yin and falling fire, qingjin and moistening lung and eliminating turbid toxic materials out of the body, as shown in clinic verification; and the prescription medicine has a good absorption effect and has good pain relieve and treatment functions on scale form cell carcinoma, undifferentiated carcinoma, adenocarcinoma and alveolar cell carcinoma.
Description
Affiliated technical field
The present invention relates to the field of Chinese medicines, relate in particular to a kind of prescription medicine and preparation method that is used for the treatment of pulmonary carcinoma.
Background technology
Pulmonary carcinoma is modal lung primary malignant tumor, most pulmonary carcinoma originates from the bronchial mucosa epithelium, therefore also claim lung bronchogenic carcinoma, be confined to person in basement membrane and be called the cancer in situ cancerous protuberance, can be in bronchial lumen or/and the lung tissue of closing on growth, and can shift diffusion by the lymph blood or through bronchus.The situation of the carcinoma speed of growth and transfer diffusion, have certain relation with histological type, the differentiation degree of carcinoma.The distribution situation right lung of pulmonary carcinoma is more than left lung, and upper leaf is more than inferior lobe.Originate from main bronchus, lobar bronchi, position is called central type carcinoma of lung near the hilus pulumonis person; Originate from below segmental bronchi, position is called peripheral type carcinoma of lung peripheral part person of lung.
Pulmonary carcinoma is divided into again squamous cell carcinoma, undifferentiated carcinoma, adenocarcinoma and alveolar cell carcinoma clinically, the modern medicine system is thought, lung cancer caused risk factor comprises that smoking causes the bronchial mucosa epithelial hyperplasia, the radioactive substances such as atmospheric pollution and Long Term Contact uranium radium bring out scale cancer and undifferentiated small cell carcinoma, and Inheritance and immune function reduce metabolic activity endocrine function imbalance etc.
Pulmonary carcinoma early symptom main manifestations is cough, low grade fever, chest pain with distension sensation, expectorant blood, show as outward the osteoarthrosis symptom, the shoulder have a back ache, hoarseness, show as serious symptom pain, hoarseness, neck surface edema and tachypnea, hydrothorax late period.To the treatment of pulmonary carcinoma, mainly contain operative therapy, chemotherapy, radiotherapy art, immunity and reverse the pulmonary carcinoma therapy at present.Though operative therapy, chemotherapy and radiotherapy have certain effect, but obvious side effect is also arranged, have a strong impact on patients ' life quality, biological immune therapy and reverse pulmonary carcinoma therapy are mainly by regulating body immune system and hormonal system, with strong body, reach the purpose for the treatment of, it is perfectly in harmony that this and Traditional Chinese Medicine are treated theory.
Traditional Chinese medical theory is thought, pulmonary carcinoma is because of deficiency of the spleen causing weakness of QI, lack of lung-YIN, deficiency of both QI and YIN, the empty tired and damage of the scorchingly hot caused body of the deficiency of YIN, the medication of should suiting the medicine to the illness, select the Chinese crude drug prescription of invigorating the spleen and replenishing QI, nourishing YIN to lower pathogenic fire, clearing the metal and protecting the lung, eliminating toxic substances to remove stasis, moistening the lung and resolving phlegm, take into account the effectiveness of cancer-resisting simultaneously, concoct according to its property classification, reach the purpose of killing tumor cell, cancerous cell.
Summary of the invention
The invention provides a kind of prescription medicine and preparation method that is used for the treatment of pulmonary carcinoma, there is the effectiveness of invigorating the spleen and replenishing QI, nourishing YIN to lower pathogenic fire, clearing the metal and protecting the lung, eliminating toxic substances to remove stasis, moistening the lung and resolving phlegm, have the merit of anti-cancer concurrently, pulmonary malignant tumour, pulmonary carcinoma are all had to significant curative effect.
For achieving the above object, technical scheme of the present invention is implemented as follows:
A kind of prescription medicine that is used for the treatment of pulmonary carcinoma, raw material composition and the parts by weight of making described effective ingredient are:
50～70 parts of 70～100 parts of Folium Ilicis Cornutaes of the Radix Rehmanniae, 55～75 parts of Cortex Lycii, 60～85 parts of Radix Ophiopogonis
32～46 parts of 35～50 portions of Herba Scutellariae Barbataes of 40～55 parts of Radixs Astragali of 45～65 parts of Herba Houttuyniae of Radix Codonopsis
15～25 parts of 18～30 parts of Folium cordylines fruticosaes of 22～36 parts of Rhizoma Atractylodis Macrocephalaes of 28～40 parts of Rhizoma Imperataes of Poria
3～12 parts of 5～15 parts of Scolopendra (processed) of 8～16 parts of Semen Armeniacae Amarums of 12～20 parts of Rhizoma Paridis of Bulbus Fritillariae Cirrhosae
Raw material composition and the parts by weight of making described effective ingredient are:
58 parts of 82 parts of Folium Ilicis Cornutaes of the Radix Rehmanniae, 62 parts of Cortex Lycii, 70 parts of Radix Ophiopogonis
37 parts of 40 portions of Herba Scutellariae Barbataes of 45 parts of Radixs Astragali of 52 parts of Herba Houttuyniae of Radix Codonopsis
18 parts of 23 parts of Folium cordylines fruticosaes of 27 parts of Rhizoma Atractylodis Macrocephalaes of 32 parts of Rhizoma Imperataes of Poria
7 parts of 9 parts of Scolopendra (processed) of 10 parts of Semen Armeniacae Amarums of 15 parts of Rhizoma Paridis of Bulbus Fritillariae Cirrhosae
A kind of preparation method that is used for the treatment of the prescription medicine of pulmonary carcinoma comprises following processing step:
(1) by the Folium cordylines fruticosae ashing, pulverize and grind into powder after mixing with Bulbus Fritillariae Cirrhosae, Rhizoma Paridis, Semen Armeniacae Amarum, Scolopendra (processed), cross 120 order fine powders, standby.
(2) Herba Houttuyniae, Rhizoma Imperatae are put into to container, mash taking juice, standby.
(3) Radix Rehmanniae, Radix Ophiopogonis, Cortex Lycii, the Radix Astragali, Herba Scutellariae Barbatae, the Rhizoma Atractylodis Macrocephalae are put into to container, add the water of six times of amounts, steaming and decocting, after 3～5 hours, is got immersion; Add the water of four times of amounts in remaining medicinal residues, steaming and decocting, after 2～3 hours, is got immersion again; Merge twice gained immersion, the ointment that heating evaporation is relative density 1.10～1.15 under 50 ℃ of environment, standby.
(4) Folium Ilicis Cornutae, Radix Codonopsis, Poria are put into to container, add the Ji Me Lao Jiu of four times of amounts, steaming and decocting, after 1～2 hour, is got immersion; Add the Ji Me Lao Jiu of triplication in remaining medicinal residues, steaming and decocting, after 1 hour, is got immersion again; Merge twice gained immersion, the ointment that heating evaporation is relative density 1.15～1.20 under 50 ℃ of environment, standby.
(5) juice fine powder of step (1) gained, step (2) made, the ointment made with step (3), step (4) mixes, and the rear quick-freezing that stirs is dry powder, with modern science technique, is prepared as the tablet product.
The property of medicine of the present invention's Chinese medicine used is as follows:
The Radix Rehmanniae: sweet in the mouth; Bitter; Cold nature.GUIXIN; Liver; Kidney channel.Nourishing YIN and clearing away heat; Removing heat from blood is enriched blood.Cure mainly the calentura excessive thirst; Interior-heat is quenched one's thirst; The hectic fever due to YIN-deficiency consumptive fever; Epidemic febrile disease is sent out speckle; Haematemesis due to heat in blood; Metrorrhagia; Hematuria; Have blood in stool; Blood deficiency and yellow complexion; Dizzy cardiopalmus; The insufficiency of blood amenorrhea." Japan hanako materia medica " carries: " control palpitation with fear labor bad, cardiopulmonary damage, spit blood, and epistaxis, married woman's metrorrhagia bruise, help muscles and bones." modern medicine study confirms, the Radix Rehmanniae is effective immunostimulant, comprises multiclass aminoacid, the saccharide beneficial to human body, and heart tonifying, diuresis, blood pressure lowering, blood sugar lowering arranged, protect the liver, the pharmacological action such as antibacterial, hemocytes increasing.
Folium Ilicis Cornutae: bitter in the mouth; Cool in nature.Enter liver; Kidney channel.Clearind deficient heat; Liver and kidney tonifying; Wind-damp dispelling.Cure mainly hectic fever due to deficiency of YIN; The cough spitting of blood; Have a dizzy spell; Soreness of the waist and knees; Rheumatic arthralgia; Vitiligo." Bencao Jingshu " carries: " this medicine directly enters meridian of Foot-SHAO YIN, takes a tonic or nourishing food to build up one's health cloudy gas, and phlegm-fire is from disappearing, as the meaning of removing burning wood away under the boiler goes out.The double pathogenic wind toxic malignant boil that can fall apart." the modern medicine study confirmation, Folium Ilicis Cornutae can increase coronary flow, strengthens myocardial contraction, and contained dicaffeoylquinic acid has and promotes more significantly release action prostacyclin.
Radix Ophiopogonis: sweet in the mouth; Micro-hardship; Cold nature.GUIXIN; Lung; The stomach warp.YIN nourishing and the production of body fluid promoting; Lung moistening clears away heart-fire.Cure mainly dryness of the lung dry cough, deficiency of YIN consumptive disease is coughed, the sore throat pharyngalgia, and Tianjin wound is thirsty, and interior-heat is quenched one's thirst, vexed insomnia, dryness of the intestine constipation." Mingyi Bielu " carries: " treat the heavy sensation of the body icteric sclera Radix Ophiopogonis, rami cardiaci inferiores is full, the asthenia exopathogenic heat, and the xerostomia excessive thirst, preventing or arresting vomiting is told, and more flaccidity falls, and reinforcing YIN-essence benefit essence, during rapid digestion of food is adjusted, protect god, determines lung qi, and settling five organs makes us fertile strong." the modern medicine study confirmation; contain the compositions such as multiple steroid saponin, carotene, phlegmatic temperament, saccharide, stigmasterol Radix Ophiopogonis; leukocyte increasing is arranged; extend the effect of antibody life period; improve immunologic function and nucleic acid synthetic ratio; the generation of the immune materials such as enhancing antibody, complement, interferon, lysozyme simultaneously, the healthy energy of enhancing is arranged, strengthen anti-evil effect.
Cortex Lycii: sweet in the mouth; Cold in nature.Enter lung; Kidney channel.Clearind deficient heat; Purte the white; Removing heat from blood.Cure mainly hectic fever due to deficiency of YIN; Hectic fever due to YIN-deficiency night sweat; The infantile malnutrition heating; Dyspnea and cough due to lung-heat; Spit blood; Epistaxis; Hematuria; Quench one's thirst." book on Chinese herbal medicine is stated " carries: " cure mainly deficient fever, alternate attacks of chills and fever, allly be shown in blood disorder, epistaxis, cough blood, cough, breathe heavily, and diseases due to endogenous heat of ZANG FU organs, apoplexy, dizzy, the convulsion epilepsy, lumbago, migratory arthralgia, beriberi, edema, fidgets due to deficiency, throb with fear, forgetful, urinary obstruction, reddish and whitish turbid urine." modern medicine study confirms, the derivant that Cortex Lycii contains guanidine, have hypoglycemic activity, and the infringement of islets of langerhans island β cellular morphology structure is had to certain effect that alleviates, and can block SNE and direct vasodilator.
Radix Codonopsis: sweet in the mouth; Property is put down.Return spleen; Lung meridian.Strengthening the spleen and tonifying the lung; Supplementing QI for promoting the production of body fluid.Cure mainly weakness of the spleen and stomach; Anorexia and loose stool; Limbs fatigue; The deficiency of the lung is breathed with cough; The spontaneous perspiration of breathing hard; The all cards of deficiency of both QI and blood." moral is joined book on Chinese herbal medicine " carries: " the lung heat clearing gold, invigorating primordial QI, open sound, helps biceps." the modern medicine study confirmation; Radix Codonopsis energy Gastrointestinal motility adjustment, antiulcer, enhancing immunologic function; to excited all influential with two kinds of nervous process of inhibition, can raise erythrocyte, hemoglobin, reticulocyte, also have the effect of slow down aging and antioxidation, radioprotective, blood pressure lowering.
Herba Houttuyniae: acrid in the mouth; Cold in nature.Enter liver; Lung meridian.Heat-clearing and toxic substances removing; Removing pus and relieving carbuncle; Inducing diuresis for treating stranguria syndrome.Cure mainly the lung abscess vomiting pus; The expectorant dyspnea of heat type is coughed; Larynx; Hematodiarrhoea; Carbuncle sore tumefacting virus; Pyretic stranguria." Chinese herbal medicine handbook commonly used is carried: " eliminating inflammation and expelling toxin, inducing diuresis to remove edema.Control upper respiratory tract infection, lung abscess, urinary tract inflammation and other position suppurative inflammation, venom." the modern medicine study confirmation; Herba Houttuyniae can strengthen the phagocytic activity of WBC; improve immunity of organisms; various microorganisms are all had to inhibitory action, also has in addition significant antagonism, antiviral, diuresis, analgesia, antitussive, hemostasis, inhibition serous secretion, promotes tissue regeneration, calmness, anti-frightened acting on.
The Radix Astragali: sweet in the mouth; Warm in nature.Enter the heart; Lung; Spleen; Kidney channel.Invigorating QI to consolidate the body surface resistance; Diuresis; Expelling pus and toxin by strengthening QI; Promoting tissue regeneration and ulcer healing.Cure mainly the cardiopalmus of breathing hard; Asthenia; Weak; Spontaneous perspiration; Night sweat; Chronic diarrhea; Proctoptosis; Body is impractical swollen; Uterine prolapse; Chronic nephritis; Carbuncle is difficult bursts; Or burst and do not hold back for a long time." Xinhua's book on Chinese herbal medicine outline " carries: " the function that invigorating QI to consolidate the body surface resistance, expelling pus and toxin by strengthening QI, granulation promoting are arranged." modern medicine study confirms; Radix Astragali main component is Radix Astragali total flavones, Radix Astragali Mongolici total polysaccharide, Radix Astragali total saponins and aminoacid etc.; have diuretic antihypertensive, anti-inflammatory analgesic, heart tonifying, antioxidant radical generates and improve the multiple pharmacological effect such as body's immunity; can act on from many aspects body, improves the related artery sexually transmitted disease (STD)s such as cardiovascular, cerebrovascular, diabetes, nephropathy and becomes the functions such as patients' hemodynamics and vascular endothelial cell.
Herba Scutellariae Barbatae: acrid in the mouth; Bitter; Cold in nature.Return lung; Liver; Kidney channel.Heat-clearing and toxic substances removing; The dissipating blood stasis hemostasis; Inducing diuresis to remove edema.Cure mainly the pyretic toxicity carbuncle; Have sore throat; Lung abscess; The intestinal carbuncle; Scrofula; Venom; Traumatic injury; Spit blood; Epistaxis; Stranguria with blood; Edema; Ascites and cancer." Quanzhou book on Chinese herbal medicine " carries: " heat clearing away, removing toxic substances, method wind, loose blood, circulation of qi promoting, diuretic, dredging collateral, removing blood stasis with potent drugs, pain relieving.Main stranguria with blood for oral administration, spit blood, epistaxis; External smelting venom, carbuncle, furuncle, innominate toxic swelling." the modern medicine study confirmation; Herba Scutellariae Barbatae has stronger antibacterial and phlegm-dispelling functions; acute cellular type leukemia hemocyte is had to significant inhibitory action; can obviously improve the percentage rate of esterase positive cell in peripheral blood lymphocyte; promote delayed allergy, increases cerebral blood flow, reduces cerebral vascular resistance; improve blood-brain barrier permeability, resists the platelet aggregation caused by Adenosine diphosphate work glycosides.
Poria: sweet in the mouth; Light; Property is put down.Enter the heart; Spleen; Lung; Kidney channel.Eliminating dampness and diuresis; Invigorating the spleen and regulating the stomach; Mind tranquilizing and the heart calming.Cure mainly dysuria; The edema distension; The phlegm retention cough with dyspnea; Vomiting; Insufficiency of the spleen lack of appetite; Let out wash with watercolours; Palpitation and restlessness; Insomnia forgetfulness; The seminal emission nebulousurine." not Lu " carries: " only quench one's thirst, like to sleep, large abdomen, drench drop, the disease due to obstruction of QI of middle-JIAO expectorant water, and edema is drenched knot.Open the breast internal organs, adjust visceral-qi, cut down the kidney heresy, long cloudy, physical strength profiting, during guarantor god keeps." the modern medicine study confirmation; Poria all has inhibitory action to staphylococcus aureus, escherichia coli, Bacillus proteus etc.; can kill the antibacterials such as leptospira; digestive system, blood system and central nervous system are had to certain protective effect; pachyman content is very high in addition, but anti-tumor activity.
Rhizoma Imperatae: sweet in the mouth; Cold in nature.Enter lung; Stomach; The heart; Urinary bladder channel.Cooling blood for hemostasis; Clearing away heat and promoting production of body fluid; Inducing diuresis for treating stranguria syndrome.Cure mainly heat in blood hemorrhage; The calentura excessive thirst; The gastric heat vomiting; Dyspnea and cough due to lung-heat; The puckery pain of dribbling urination; Edema; Jaundice." herbal classic " carries: " main impairment caused by overstrain weakness with emaciation, invigorating the spleen and replenishing QI, except blood stasis, blood close cold and heat, diuresis." modern medicine study shows; Rhizoma Imperatae has significant diuresis, obviously shortens the recalcification time of blood plasma, and Fu Shi and Song's Shigella flexneri are had to obvious inhibitory action; contained Coixol has inhibitory action to contraction and the metabolism of skeletal muscle, also has in addition the effects such as calmness, antipyretic-antalgic.
The Rhizoma Atractylodis Macrocephalae: bitter in the mouth; Sweet; Warm in nature.Return spleen; The stomach warp.Invigorating the spleen and benefiting QI; The dampness diuretic; Hidroschesis; Antiabortive.Cure mainly deficiency-weakness of spleen-QI; Spiritlessness and weakness; Lack of appetite abdominal distention; Large loose stool is thin; Fluid-retention stagnating in the interior; Dysuria; Edema; Dizziness due to fluid-retention; Arthralgia chiefly caused by damp pathogen is ached; Spontaneous sweating due to deficiency of QI; Frequent fetal movement." herbal classic is met former " carries: " the dehumidifying benefit is dry, and the expectorant diuretic, control anemofrigid-damp arthralgia, dead flesh convulsion subcutaneous ulcer, and blood between loose waist umbilicus, and middle QI invigorating, slake thirst and help produce saliva, the hidroschesis heat extraction." the modern medicine study confirmation; the Rhizoma Atractylodis Macrocephalae has effect strong and that improve body resistance against diseases; strengthen the phagocytic function of reticuloendothelial system; strengthen phagocytic activity of leukocytes; leukopenia is had to leukogenic effect; the raising lymhocyte transformation rate, promotes cellular immune function, and staphylococcus aureus, Hemolytic streptococcus, viridans streptococci, streptococcus pneumoniae, meningococcus, diphtheria corynebacterium, bacillus subtilis are had to inhibitory action in various degree.
Folium cordylines fruticosae: sweet in the mouth; Light; Property is put down; Mild toxicity.Enter liver; The stomach warp.Regulating QI to relieve pain; The dissipating blood stasis hemostasis; Subduing swelling and detoxicating.Cure mainly stagnation of liver-QI and stomach-QI pain; Amenorrhea; Spit blood; Have blood in stool; Dysentery; Toxic swelling; Traumatic hemorrhage; Traumatic injury." it is former that book on Chinese herbal medicine is asked " carries: " dissipating blood stasis hemostasis, blood in the muscles and bones of living.Control the inferior blood, haematemesis, decoct meat.Treating swelling and pain by traumatic injury, apply it with former distiller grains; Add onion, vinegar and apply it, pull out all malicious wind, wind syndrome due to invasion of wind when drinking." modern medicine study shows, Folium cordylines fruticosae contains multiple phenols, aminoacid and sugar, and significant hemostasis, calmness, antiinflammatory action are arranged, and also finds that there is in recent years antitumaous effect.
Bulbus Fritillariae Cirrhosae: sweet in the mouth; Bitter; Cold nature.Return lung; Heart channel.Clearing heat and moistening lung; Preventing phlegm from forming and stopping coughing; Mass dissipating and swelling eliminating.Cure mainly the deficiency of the lung; Chronic cough; Cough due to consumptive disease; Cough caused by dryness-heat; Lung abscess; Scrofula; Carbuncle; Acute mastitis." Changsha medicine solution " carries: " property of Bulbus Fritillariae Uninbracteatae bitter cold, the cool gold that expels the heat-evil, the turbid descending expectorant, its power is non-little, so clearing heat in the lung and here praiseworthy unbeaten gastric qi is very." the modern medicine study confirmation, Bulbus Fritillariae Cirrhosae has significant antitussive and phlegm-dispelling functions, significantly suppresses pepsin and stress ulcer, suppresses the central nervous system.
Rhizoma Paridis: bitter in the mouth; Cold in nature; Mild toxicity.Enter Liver Channel.Heat-clearing and toxic substances removing; Reducing swelling and alleviating pain; Cool liver arresting convulsion.Cure mainly carbuncle sore tumefacting virus; The pharyngeal swelling laryngalgia; Acute mastitis; Snake bite and insect sting; Traumatic pain; Liver-heat is twitched." it is former that book on Chinese herbal medicine is asked " carries: " strengthening the spleen juice, rise the clearing heat in QI system of stomach, up in lung, with beneficial blood gas.Strong lean kidney, the sixth of the twelve Earthly Branches the consumptive disease internal injury of coughing.Invigorate blood circulation, hemostasis, detumescence, removing toxic substances." modern medicine study shows; Rhizoma Paridis have significantly relieving asthma, antitussive action; the various pathogens such as Bacterium entericum and pyococcus are had to antibacterial action; ethanol extract can be killed Leptospira; influenza A virus is had to inhibitory action, multiplex in treatment chronic tracheitis, neurodermatitis and multiple surgery inflammation clinically.
Semen Armeniacae Amarum: bitter in the mouth; Warm in nature; Poisonous.Enter lung; Spleen; Large intestine channel.Expelling phlegm for arresting cough; Relieving asthma; Intestine moistening; Lower air to open numbness.Cure mainly the exogenous cough; Dyspnea with fullness of the chest; The cough due to dryness; The cold renal mass; Infantile convulsion; The thoracic obstruction; Stomachache due to dyspepsia; Metrorrhagia; Deaf; Infantile malnutrition with edema and abdominal distention; Damp and hot stranguria; Scabies; Sore throat; The dryness of the intestine constipation." property of medicine opinion " carries: " control abdomen numbness obstructed, diaphoresis, main epidemic febrile disease.Control completely pain of spasm in the epigastrium, except trusted subordinate's unhappiness, treat the lung qi cough, dyspnea, the profit cardiopulmonary, can make soup with cheese, benefit profit information." the modern medicine study confirmation; Semen Armeniacae Amarum can effectively be controlled the content of cholesterol in human body; significantly reduce the initiation potential of heart disease and multiple chronic disease, has the effects such as lung moistening, cough-relieving, laxation, and the diseases such as dry cough without phlegm, chronic cough of deficiency lung are had to certain mitigation.
Scolopendra (processed): acrid in the mouth; Warm in nature; Poisonous.Enter Liver Channel.Expelling wind and relieving convulsion; Removing obstruction in the collateral to relieve pain; Dispersing pathogen accumulation.Indications convulsions; seizures; convulsion; the outlet; tetanus; rheumatoid stubborn weakness; prejudiced headache; snakebite; sore; scrofula." detailed outline " carries: " control the infantile convulsion tetany caused by wind pathogen, the infantum tetanus locked mouth, erysipelas, tinea alba, scrofula, inguinal bubo, anal fistula, snakebite, dial the pus detumescence." the modern medicine study confirmation, Scolopendra extract has certain effect to animal transplanting tumor, and multiple fungus is had to inhibitory action in various degree, rising IgG and E rosette forming rate, Promote immunity function.
The present invention compared with prior art, has following beneficial effect:
Selection of the present invention is precise and penetrating, for lung cancer caused deficiency of the spleen causing weakness of QI, lack of lung-YIN, deficiency of both QI and YIN, the deficiency of YIN scorchingly hot etc. pathogenic because of, among selecting invigorating the spleen and replenishing QI, nourishing YIN to lower pathogenic fire, clearing the metal and protecting the lung, eliminating toxic substances to remove stasis, the process of preparing Chinese medicine of medical material reasonable compatibility forms, good through the clinical verification assimilation effect, squamous cell carcinoma, undifferentiated carcinoma, adenocarcinoma and alveolar cell carcinoma are all had to good pain relieving and therapeutical effect.
The specific embodiment
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material of effective ingredient of the present invention forms and weight is:
Radix Rehmanniae 90g Folium Ilicis Cornutae 80g 70g Radix Ophiopogonis Cortex Lycii 65g
Radix Codonopsis 60g Herba Houttuyniae 50g Radix Astragali 47g Herba Scutellariae Barbatae 44g
Poria 38g Rhizoma Imperatae 33g Rhizoma Atractylodis Macrocephalae 29g Folium cordylines fruticosae 23g
Bulbus Fritillariae Cirrhosae 18g Rhizoma Paridis 14g Semen Armeniacae Amarum 12g Scolopendra (processed) 10g
The processing step of process for preparing medicine of the present invention is:
(1) by the Folium cordylines fruticosae ashing, pulverize and grind into powder after mixing with Bulbus Fritillariae Cirrhosae, Rhizoma Paridis, Semen Armeniacae Amarum, Scolopendra (processed), cross 120 order fine powders, standby.
(2) Herba Houttuyniae, Rhizoma Imperatae are put into to container, mash taking juice, standby.
(3) Radix Rehmanniae, Radix Ophiopogonis, Cortex Lycii, the Radix Astragali, Herba Scutellariae Barbatae, the Rhizoma Atractylodis Macrocephalae are put into to container, add the water of six times of amounts, steaming and decocting, after 3～5 hours, is got immersion; Add the water of four times of amounts in remaining medicinal residues, steaming and decocting, after 2～3 hours, is got immersion again; Merge twice gained immersion, the ointment that heating evaporation is relative density 1.10～1.15 under 50 ℃ of environment, standby.
(4) Folium Ilicis Cornutae, Radix Codonopsis, Poria are put into to container, add the Ji Me Lao Jiu of four times of amounts, steaming and decocting, after 1～2 hour, is got immersion; Add the Ji Me Lao Jiu of triplication in remaining medicinal residues, steaming and decocting, after 1 hour, is got immersion again; Merge twice gained immersion, the ointment that heating evaporation is relative density 1.15～1.20 under 50 ℃ of environment, standby.
(5) juice fine powder of step (1) gained, step (2) made, the ointment made with step (3), step (4) mixes, and the rear quick-freezing that stirs is dry powder, with modern science technique, is prepared as the tablet product.
Usage and dosage: adult every day 3 times, each 3～5, one hour after meal with warm water delivery service, advanced lung cancer patient every day 4～5 times, each 4～6 15 days is a course for the treatment of, general 2～3 courses for the treatment of are the alleviating pain symptom obviously, alleviates the pulmonary carcinoma symptom 4～6 courses for the treatment of.
Embodiment 2
The raw material of effective ingredient of the present invention forms and weight is:
Radix Rehmanniae 82g Folium Ilicis Cornutae 70g 62g Radix Ophiopogonis Cortex Lycii 58g
Radix Codonopsis 52g Herba Houttuyniae 45g Radix Astragali 40g Herba Scutellariae Barbatae 37g
Poria 32g Rhizoma Imperatae 27g Rhizoma Atractylodis Macrocephalae 23g Folium cordylines fruticosae 18g
Bulbus Fritillariae Cirrhosae 15g Rhizoma Paridis 10g Semen Armeniacae Amarum 9g Scolopendra (processed) 7g
Process for preparing medicine processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 3
The raw material of effective ingredient of the present invention forms and parts by weight are:
Radix Rehmanniae 75g Folium Ilicis Cornutae 65g 58g Radix Ophiopogonis Cortex Lycii 54g
Radix Codonopsis 48g Herba Houttuyniae 44g Radix Astragali 38g Herba Scutellariae Barbatae 34g
Poria 32g Rhizoma Imperatae 25g Rhizoma Atractylodis Macrocephalae 22g Folium cordylines fruticosae 18g
Bulbus Fritillariae Cirrhosae 15g Rhizoma Paridis 10g Semen Armeniacae Amarum 8g Scolopendra (processed) 5g
Process for preparing medicine processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Clinical data:
The clinical verification data show, prescription medicine of the present invention all has significant curative effect to small cell lung cancer and nonsmall-cell lung cancer, the squamous cell carcinoma course of disease is controlled to effective percentage and reach 78.2%, the transfer of undifferentiated carcinoma is controlled to effective percentage and reach 67.4%, growth and blood control effective percentage to adenocarcinoma reach 68.2%, sending out of alveolar cell carcinoma controlled to effective percentage with hematogenous metastasis and reach 82.6%, can obviously alleviate the pain symptom of all types of pulmonary carcinoma, help to recover pulmonary's body function, the state of an illness that is applicable to clinical pulmonary carcinoma is controlled and treatment.
Claims (3)
1. a prescription medicine that is used for the treatment of pulmonary carcinoma is characterized in that: the raw material of making described effective ingredient forms and parts by weight are:
50～70 parts of 70～100 parts of Folium Ilicis Cornutaes of the Radix Rehmanniae, 55～75 parts of Cortex Lycii, 60～85 parts of Radix Ophiopogonis
32～46 parts of 35～50 portions of Herba Scutellariae Barbataes of 40～55 parts of Radixs Astragali of 45～65 parts of Herba Houttuyniae of Radix Codonopsis
15～25 parts of 18～30 parts of Folium cordylines fruticosaes of 22～36 parts of Rhizoma Atractylodis Macrocephalaes of 28～40 parts of Rhizoma Imperataes of Poria
3～12 parts of 5～15 parts of Scolopendra (processed) of 8～16 parts of Semen Armeniacae Amarums of 12～20 parts of Rhizoma Paridis of Bulbus Fritillariae Cirrhosae.
2. a kind of prescription medicine that is used for the treatment of pulmonary carcinoma according to claim 1 is characterized in that: the raw material of making described effective ingredient forms and parts by weight are:
58 parts of 82 parts of Folium Ilicis Cornutaes of the Radix Rehmanniae, 62 parts of Cortex Lycii, 70 parts of Radix Ophiopogonis
37 parts of 40 portions of Herba Scutellariae Barbataes of 45 parts of Radixs Astragali of 52 parts of Herba Houttuyniae of Radix Codonopsis
18 parts of 23 parts of Folium cordylines fruticosaes of 27 parts of Rhizoma Atractylodis Macrocephalaes of 32 parts of Rhizoma Imperataes of Poria
7 parts of 9 parts of Scolopendra (processed) of 10 parts of Semen Armeniacae Amarums of 15 parts of Rhizoma Paridis of Bulbus Fritillariae Cirrhosae.
3. a preparation method that is used for the treatment of the prescription medicine of pulmonary carcinoma is characterized in that: comprise following processing step:
(1) by the Folium cordylines fruticosae ashing, pulverize and grind into powder after mixing with Bulbus Fritillariae Cirrhosae, Rhizoma Paridis, Semen Armeniacae Amarum, Scolopendra (processed), cross 120 order fine powders, standby.
(2) Herba Houttuyniae, Rhizoma Imperatae are put into to container, mash taking juice, standby.
(3) Radix Rehmanniae, Radix Ophiopogonis, Cortex Lycii, the Radix Astragali, Herba Scutellariae Barbatae, the Rhizoma Atractylodis Macrocephalae are put into to container, add the water of six times of amounts, steaming and decocting, after 3～5 hours, is got immersion; Add the water of four times of amounts in remaining medicinal residues, steaming and decocting, after 2～3 hours, is got immersion again; Merge twice gained immersion, the ointment that heating evaporation is relative density 1.10～1.15 under 50 ℃ of environment, standby.
(4) Folium Ilicis Cornutae, Radix Codonopsis, Poria are put into to container, add the Ji Me Lao Jiu of four times of amounts, steaming and decocting, after 1～2 hour, is got immersion; Add the Ji Me Lao Jiu of triplication in remaining medicinal residues, steaming and decocting, after 1 hour, is got immersion again; Merge twice gained immersion, the ointment that heating evaporation is relative density 1.15～1.20 under 50 ℃ of environment, standby.
(5) juice fine powder of step (1) gained, step (2) made, the ointment made with step (3), step (4) mixes, and the rear quick-freezing that stirs is dry powder, with modern science technique, is prepared as the tablet product.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103611003A (en) * | 2013-11-22 | 2014-03-05 | 杨兆辉 | Traditional Chinese medicine composition for improving somatic functions of patients with lung cancer and preparation method thereof |
| CN104474327A (en) * | 2014-11-26 | 2015-04-01 | 魏建强 | Traditional Chinese medicine composition for treating lung cancer |
| CN104771729A (en) * | 2015-04-03 | 2015-07-15 | 江蕾 | Traditional Chinese medicine pill assisted to treat lung cancer and preparation method thereof |
| CN105833061A (en) * | 2015-12-17 | 2016-08-10 | 夏修菲 | Traditional Chinese medicine capsule for treating primary malignant lung tumor |
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2012
- 2012-12-11 CN CN 201210533108 patent/CN102940808A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103611003A (en) * | 2013-11-22 | 2014-03-05 | 杨兆辉 | Traditional Chinese medicine composition for improving somatic functions of patients with lung cancer and preparation method thereof |
| CN104474327A (en) * | 2014-11-26 | 2015-04-01 | 魏建强 | Traditional Chinese medicine composition for treating lung cancer |
| CN104771729A (en) * | 2015-04-03 | 2015-07-15 | 江蕾 | Traditional Chinese medicine pill assisted to treat lung cancer and preparation method thereof |
| CN105833061A (en) * | 2015-12-17 | 2016-08-10 | 夏修菲 | Traditional Chinese medicine capsule for treating primary malignant lung tumor |
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Application publication date: 20130227 |