CN102949679A - Medicine for curing lung cancer and preparation method thereof - Google Patents
Medicine for curing lung cancer and preparation method thereof Download PDFInfo
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- CN102949679A CN102949679A CN 201210514464 CN201210514464A CN102949679A CN 102949679 A CN102949679 A CN 102949679A CN 201210514464 CN201210514464 CN 201210514464 CN 201210514464 A CN201210514464 A CN 201210514464A CN 102949679 A CN102949679 A CN 102949679A
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Abstract
The invention discloses a medicine for curing lung cancer and a preparation method thereof, belonging to the field of traditional Chinese medicine. The medicine disclosed by the invention comprises the following materials in part by weight: 45-65 parts of radix asparagi, 45-60 parts of radix ophiopogonis, 40-60 parts of schisandra chinensis, 35-55 parts of rhizoma phragmitis, 35-50 parts of bulbus fritilariae, 30-50 parts of root of straight ladybell, 25-45 parts of holly leaf, 25-40 parts of astragalus mongholicus, 20-35 parts of white atractylodes rhizome, 15-35 parts of curcuma zedoary, 15-30 parts of sculellaria barbata, 15-25 parts of fructus trichosanthis, 10-25 parts of radix peucedani, 10-20 parts of almond, 5-15 parts of houttuynia cordata, and 5-10 parts of oldenlandia diffusa. The medicine disclosed by the invention has compatibility rationality, has a primary action of replenishing qi to invigorate the spleen and an auxiliary action of detoxifying and moistening lung and nourishing yin to lessen fire for deficient spleen and weak vital energy, deficiency of lung yi, yin deficiency and heat-toxicity, which cause lung disease, and has the functions of invigorating spleen and replenishing qi, nourishing yin to lessen fire, moistening lung, detoxifying and reducing phlegm. Through clinical verifications, the absorbing effect is good, and a remarkable curative effect is provided for lung tumor lesion and lung cancer patient at each development period.
Description
Affiliated technical field
The present invention relates to the field of Chinese medicines, relate in particular to a kind of medicine and preparation method that is used for the treatment of pulmonary carcinoma.
Background technology
Pulmonary carcinoma is common lung primary malignant tumor, and most pulmonary carcinoma originate from the bronchial mucosa upper strata, refers generally to the cancer of pulmonary parenchyma section, can be in bronchial lumen or the lung tissue of closing on growth, and can shift diffusion by the lymph blood or through bronchus.The carcinoma speed of growth and shift the situation of diffusion has certain relation with histological type, the differentiation degree biological characteristics of carcinoma.Pulmonary carcinoma is divided into squamous cell carcinoma, undifferentiated carcinoma, adenocarcinoma and alveolar cell carcinoma clinically, and squamous cell carcinoma growth development speed ratio is slower, and the course of disease is longer, and is responsive to radiation and chemotherapy, and at first through lymph metastasis, hematogenous metastasis occurs evening; The undifferentiated carcinoma grade of malignancy is high, and growth is fast, lymph occurs earlier and blood extensively shifts, to radiation and amic therapy method sensitivity, poor prognosis; Adenocarcinoma is peripheral type carcinoma of lung, does not generally have in early days obvious clinical symptoms, and general growth is slower, but Development hematogenous metastasis sometimes, then occur evening in lymph metastasis; The alveolar cell silver stain is higher, and it is slower to grow, and cancerous cell is not invaded alveolar septum along ramuscule pipe alveolar duct and alveolar wall growth.
The treatment of pulmonary carcinoma is Chemo-Therapy therapy, Radiotherapy, biological immune therapy, reverse pulmonary carcinoma therapy for treating and the operative surgery iatrotechnics of adopting clinically more.The chemotherapy meeting suppresses medulla hematopoietic system, causes leukocyte and hematoblastic decline, thereby suppresses the fearful pathological changes such as the endless propagation of cell, transfer; The radiotherapy complication is more, even causes partial loss of function, and is not intact for the late tumor patient therapeutic effect, and patient's body constitution is not suitable for radiotherapy when relatively poor or older; The operative surgery treatment is large to the infringement of body, and survival rates is lower; Biological immune treatment and reverse pulmonary carcinoma therapy all are to utilize the immunoreation that activates body self, supervision, killing tumor cell, control or adjustment cell metabolism.
Traditional Chinese medical theory is thought, pulmonary carcinoma is owing to deficiency of the spleen causing weakness of QI, lack of lung-YIN, hyperactivity of deficient fire, deficiency of both QI and YIN, the scorchingly hot pulmonary lesion that causes that waits of the deficiency of YIN, be the biological immune therapy of wanting, that is to say to treat clinically pulmonary carcinoma and the medical knowledge place of reversing the pulmonary carcinoma therapy when reducing phlegm take invigorating the spleen and replenishing QI, nourishing YIN to lower pathogenic fire, clearing heat in the lung lung moistening, detoxifcation.Through clinical use checking, reasonably Chinese prescription is to various types of pulmonary carcinoma, phase pulmonary carcinoma morning, noon and afternoon, lung cancer metastasis has extraordinary curative effect, the Chinese medicinal ingredients specific drugs enters the inside of lung carcinoma cell with molecularity, activate the lung carcinoma cell reversing function, lung carcinoma cell changes healthy body cell into, can effectively control the development speed of pulmonary carcinoma, directly kill free cancerous cell, the control cancerous cell shifts again, activate human body immune function, simultaneously also can with the chemotherapy of modern medicine, X-ray therapy is carried out simultaneously, synergism, and minimizing is put, the side effect of chemotherapy.
Summary of the invention
The invention provides a kind of medicine that is used for the treatment of pulmonary carcinoma, have invigorating the spleen and replenishing QI, nourishing YIN to lower pathogenic fire, clearing heat in the lung lung moistening, detoxifcation clears phlegm, all kinds and the pulmonary carcinoma of different periods of expansion are all had good therapeutic effect.
For achieving the above object, technical scheme of the present invention is implemented as follows:
A kind of medicine that is used for the treatment of pulmonary carcinoma, raw material composition and the parts by weight of making described effective ingredient are:
35～55 parts of 40～60 parts of Rhizoma Phragmitiss of Radix Asparagi 45～60 parts of Fructus Schisandrae Chinensis, 45～65 parts of Radix Ophiopogonis
25～40 parts of 25～45 parts of Radixs Astragali of 30～50 parts of Folium Ilicis Cornutaes of 35～50 parts of Radix Adenophorae (Radix Glehniae) of Bulbus Fritillariae Cirrhosae
15～25 parts of 15～30 parts of Fructus Trichosanthis of 15～35 portions of Herba Scutellariae Barbataes of 20～35 parts of Rhizoma Curcumae of the Rhizoma Atractylodis Macrocephalae
5～10 parts of 5～15 parts of Herba Hedyotidis Diffusaes of 10～20 parts of Herba Houttuyniae of 10～25 parts of Semen Armeniacae Amarums of Radix Peucedani
Raw material composition and the parts by weight of making described effective ingredient are:
38～52 parts of 43～58 parts of Rhizoma Phragmitiss of Radix Asparagi 47～57 parts of Fructus Schisandrae Chinensis, 48～62 parts of Radix Ophiopogonis
27～37 parts of 28～42 parts of Radixs Astragali of 32～46 parts of Folium Ilicis Cornutaes of 37～47 parts of Radix Adenophorae (Radix Glehniae) of Bulbus Fritillariae Cirrhosae
16～22 parts of 17～28 parts of Fructus Trichosanthis of 18～32 portions of Herba Scutellariae Barbataes of 23～33 parts of Rhizoma Curcumae of the Rhizoma Atractylodis Macrocephalae
6～9 parts of 8～12 parts of Herba Hedyotidis Diffusaes of 12～18 parts of Herba Houttuyniae of 13～22 parts of Semen Armeniacae Amarums of Radix Peucedani
Raw material composition and the parts by weight of making described effective ingredient are:
45 parts of 50 parts of Rhizoma Phragmitiss of Radix Asparagi 52 parts of Fructus Schisandrae Chinensis, 55 parts of Radix Ophiopogonis
32 parts of 35 parts of Radixs Astragali of 38 parts of Folium Ilicis Cornutaes of 42 parts of Radix Adenophorae (Radix Glehniae) of Bulbus Fritillariae Cirrhosae
19 parts of 22 parts of Fructus Trichosanthis of 25 portions of Herba Scutellariae Barbataes of 28 parts of Rhizoma Curcumae of the Rhizoma Atractylodis Macrocephalae
8 parts of 10 parts of Herba Hedyotidis Diffusaes of 15 parts of Herba Houttuyniae of 17 parts of Semen Armeniacae Amarums of Radix Peucedani
A kind of preparation method that is used for the treatment of the medicine of pulmonary carcinoma comprises following processing step:
(1) Bulbus Fritillariae Cirrhosae, Rhizoma Curcumae, Semen Armeniacae Amarum are ground into powder after pulverizing, crossed 120 order fine powders, for subsequent use.
(2) Radix Astragali is mixed thoroughly with refined honey, with slow fire fry to the surface be glassy yellow and tack-free after, cool rear pulverizing and grind into powder, cross 120 order fine powders, for subsequent use.
(3) Radix Asparagi, Radix Ophiopogonis, Rhizoma Phragmitis, Radix Adenophorae (Radix Glehniae), the Rhizoma Atractylodis Macrocephalae, Herba Scutellariae Barbatae, Fructus Trichosanthis, Radix Peucedani, Herba Houttuyniae, Herba Hedyotidis Diffusae are put into container, add the water of six times of amounts, soak after 12～14 hours, get immersion; The water that adds again again four times of amounts in remaining medicinal residues soaked after 8～10 hours, got immersion; Merge twice gained immersion, heating evaporation is the ointment of relative density 1.15～1.20 under 60 ℃ of environment, and is for subsequent use.
(4) Fructus Schisandrae Chinensis, Folium Ilicis Cornutae are put into container, add the ethanol of triplication, soak after 4～6 hours, get immersion; The ethanol that adds again doubling dose in remaining medicinal residues soaked after 3～5 hours, got immersion; Merge twice gained immersion, heating evaporation is the ointment of relative density 1.10～1.15 under the room temperature environment, and is for subsequent use.
(5) with the fine powder of step (1), step (2) gained, the ointment that makes with step (3), step (4) mixes, and the rear lyophilizing that stirs is prepared as the tablet product.
The property of medicine of the used Chinese medicine of the present invention is as follows:
Radix Asparagi: sweet in the mouth; Bitter; Cold in nature; Enter lung; Kidney channel.Nourshing Yin and drynsessmoistening prescription; The lung heat clearing pathogenic fire reducing.Cough caused by dryness-heat; Deficiency of YIN chronic cough; Consumption of YIN caused by febrile disease; Interior-heat is quenched one's thirst." book on Chinese herbal medicine converges and says " carries: " except inclined to one side numbness, bone strengthening marrow person, because lung-heat becomes flaccidity, the kidney-heat marrow is withered, and the inclined to one side numbness person of the withered not Rong Ercheng of muscle also." modern medicine study confirms; Radix Asparagi has in various degree bacteriostasis to various pathogens; acute lymphoblastic type leukemia, chronic myelocytic leukemia and the leukocytic dehydrogenase of acute monocyte type leukaemic are had certain inhibitory action, and can suppress the leukocytic breathing of acute lymphoblastic type leukaemic.
Radix Ophiopogonis: sweet in the mouth; Little hardship; Cold nature.GUIXIN; Lung; The stomach warp.YIN nourishing and the production of body fluid promoting; Lung moistening clears away heart-fire.Cure mainly dryness of the lung dry cough, deficiency of YIN consumptive disease is coughed, the sore throat pharyngalgia, and Tianjin wound is thirsty, and interior-heat is quenched one's thirst." Mingyi Bielu " carries: " treat the heavy sensation of the body icteric sclera, rami cardiaci inferiores is full, the asthenia exopathogenic heat, and the xerostomia excessive thirst, preventing or arresting vomiting is told, and the flaccidity of healing falls, and the reinforcing YIN-essence benefit is smart, during rapid digestion of food is transferred, protects god, decides lung qi, settling five organs." the modern medicine study confirmation; contain the compositions such as multiple steroid saponin, carotene, phlegmatic temperament, saccharide, stigmasterol Radix Ophiopogonis; leukocyte increasing is arranged; prolong the effect of antibody life period; improve immunologic function and nucleic acid synthetic ratio; the generation of the immune materials such as enhancing antibody, complement, interferon, lysozyme, the effect that strengthens healthy energy, strengthens anti-heresy is arranged.
Fructus Schisandrae Chinensis: acrid in the mouth; Bitter; Warm in nature.Restrain astringent or styptic treatment for spontaneous sweating; Supplementing QI for promoting the production of body fluid; Kidney calming; Expelling wind and removing dampness; Vital energy regualting and blood circulation-promoting.Cure mainly rheumatic ostalgia; Stomachache; Nephritis." herbal classic " carries: " main QI invigorating, cough with dyspnea, the thin degree of impairment caused by overstrain, tonifying for the deficiency, reinforcing YIN-essence." the modern medicine study confirmation; Fructus Schisandrae Chinensis contains abundant organic acid, vitamin, flavonoid, phytosterol and the lignan of potent reactivation is arranged; it also is one of minority medical material that has concurrently essence, gas, refreshing three large tonifications, the strong liver of energy QI invigorating, the efficient of promoting the cells exclude refuse, supply more oxygen, construction and uses energy.
Rhizoma Phragmitis: sweet in the mouth; Cold in nature.Enter lung; Stomach; Urinary bladder channel.Clearing away heat and promoting production of body fluid; Relieve restlessness and prevent vomiting; Diuresis; Rash.Cure mainly the calentura excessive thirst; Gastropyretic vomiting; The cough due to lung-heat; The lung abscess vomiting pus; Pyretic stranguria; Measles; Separate Fugu ocellatus ichthyotoxin." beautiful Chinese catalpa medicine solution " carries: " fall clearly the lung stomach, disappear and swing restlessness with depression, promoting the production of body fluid to quench thirst, the regretful Nang of the sound of vomiting chokes except vomitting lower food, controlling." the modern medicine study confirmation, the contained Coixol of Rhizoma Phragmitis has inhibitory action to skeletal muscle, and contained tricin has relaxation effect to intestinal tube, increases thyroxine in the blood, prevents the epinephrine oxidation, also has in addition antitumaous effect.
Bulbus Fritillariae Cirrhosae: sweet in the mouth; Bitter; Cold nature.Return lung; Heart channel.Clearing heat and moistening lung; Preventing phlegm from forming and stopping coughing; Mass dissipating and swelling eliminating.Cure mainly the deficiency of the lung; Chronic cough; Cough due to consumptive disease; Cough caused by dryness-heat; Lung abscess; Scrofula; Carbuncle." Changsha medicine solution " carries: " property of Bulbus Fritillariae Uninbracteatae bitter cold, the cool gold that expels the heat-evil, the turbid descending expectorant, its power is non-little, right clearing heat in the lung and here praiseworthy unbeaten gastric qi is very." the modern medicine study confirmation, Bulbus Fritillariae Cirrhosae has significant antitussive and phlegm-dispelling functions effect, and pepsin is had significant inhibitory action, can suppress stress ulcer, suppresses the central nervous system.
Radix Adenophorae (Radix Glehniae): sweet in the mouth; Little hardship; Cold nature.Return lung; The stomach warp.Replenishing YIN and removing heat; Moistening the lung and resolving phlegm; Reinforcing stomach reg fluid.Cure mainly deficiency of YIN chronic cough; The consumptive disease expectorant blood of coughing; Cough caused by dryness expectorant is few; The deficiency-heat sore throat; Tianjin wound is thirsty.Compendium of Material Medica is carried: " sweet light and cold, its body is gently empty, and special tonifying the lung gas, thereby strengthening the spleen and kidney are so gold can be subjected to fiery gram person to should it.YANG invigorating and give birth to cloudy, nourishing YIN and sun processed." the modern medicine study confirmation; Radix Adenophorae (Radix Glehniae) has the raising lymhocyte transformation rate; leukocyte increasing; strengthen macrophage phagocytic function; prolong the effects such as antibody life period; analgesic, the effect of easing pain, eliminate the phlegm, relieving asthma is arranged, can strengthen the immunologic function of body fluid and cell, and irritability and Drug gastric ulcer are had protection and inhibitory action.
Folium Ilicis Cornutae: bitter in the mouth; Cool in nature.Enter liver; Kidney channel.Clearind deficient heat; Liver and kidney tonifying; Wind-damp dispelling.Cure mainly hectic fever due to deficiency of YIN; The cough spitting of blood; Have a dizzy spell; Soreness of the waist and knees; Rheumatic arthralgia." Bencao Jingshu " carries: " this medicine directly enters meridian of Foot-SHAO YIN, takes a tonic or nourishing food to build up one's health cloudy gas, and then phlegm-fire is from disappearing, and goes out such as the meaning of removing burning wood away under the boiler.The double pathogenic wind toxic malignant boil that can fall apart." modern medicine study confirms that Folium Ilicis Cornutae can increase coronary flow, strengthens myocardial contraction, contained dicaffeoylquinic acid has prostacyclin and promotes more significantly release action.
The Radix Astragali: sweet in the mouth; Warm in nature.Enter the heart; Lung; Spleen; Kidney channel.Invigorating QI to consolidate the body surface resistance; Expelling pus and toxin by strengthening QI.Cure mainly the cardiopalmus of breathing hard; Asthenia; Weak; Spontaneous perspiration; Night sweat; Chronic diarrhea; Body is impractical swollen; Chronic nephritis; Carbuncle is difficult bursts; Or burst and do not hold back for a long time." Xinhua's book on Chinese herbal medicine outline " carries: " invigorating QI to consolidate the body surface resistance, expelling pus and toxin by strengthening QI, granulation promoting.”
Modern medicine study confirms that Radix Astragali main component is Radix Astragali total flavones, Radix Astragali Mongolici total polysaccharide, Radix Astragali total saponins and aminoacid etc., has the multiple pharmacological effect such as diuretic antihypertensive, anti-inflammatory analgesic, heart tonifying, antioxidant radical generation and raising body's immunity.
The Rhizoma Atractylodis Macrocephalae: bitter in the mouth; Sweet; Warm in nature.Return spleen; The stomach warp.Invigorating the spleen and benefiting QI; The dampness diuretic.Cure mainly deficiency-weakness of spleen-QI; Spiritlessness and weakness; Large loose stool is thin; Fluid-retention stagnating in the interior; Dysuria; Edema; Dizziness due to fluid-retention; Arthralgia chiefly caused by damp pathogen is ached; Spontaneous sweating due to deficiency of QI." herbal classic is met former " carries: " the dehumidifying benefit is dry, and the expectorant diuretic is controlled anemofrigid-damp arthralgia, dead flesh convulsion subcutaneous ulcer, blood between loose waist umbilicus, contrary gas pain in the abdomen; With middle QI invigorating, to slake thirst and help produce saliva, the hidroschesis heat extraction advances diet." modern medicine study confirms; the effect that the Rhizoma Atractylodis Macrocephalae has strong effect and improves body resistance against diseases; can strengthen the phagocytic function of reticuloendothelial system; improve lymhocyte transformation rate; promote cellular immune function has in various degree inhibitory action to staphylococcus aureus, Hemolytic streptococcus, viridans streptococci, streptococcus pneumoniae, meningococcus, diphtheria corynebacterium, bacillus subtilis.
Rhizoma Curcumae: acrid in the mouth; Bitter; Warm in nature.Return liver; Spleen channel.The circulation of qi promoting removing blood stasis; The removing food stagnancy pain relieving.It is pained to cure mainly vim and vigour; Eating accumulation; Abdominal distention; Amenorrhea due to stagnation of blood; Dysmenorrhea; WEIJIA tumor mass in the abdomen." medicineization justice " carries: " acrid in the mouth is strong, specializes in the blood in the gas, and the main removing mass heavily fortified point that disappears removes to gather the addiction piece, and the amenorrhea blood stasis is pounced on newspaper pain." the modern medicine study confirmation; Rhizoma Curcumae has obvious inhibition and destruction to the growth of multiple tumor strain; tumor, the metabolism of cancerous cell nuclear are had inhibitory action; significantly improve the content of blood medium-sized lymphocyte; strengthen the oncocyte immunogenicity; temptation or promotion body are to the immunological rejection of tumor, raising the effect of radiation therapy.
Herba Scutellariae Barbatae: acrid in the mouth; Bitter; Cold in nature.Return lung; Liver; Kidney channel.Heat-clearing and toxic substances removing; The dissipating blood stasis hemostasis; Inducing diuresis to remove edema.Cure mainly the pyretic toxicity carbuncle; Lung abscess; The intestinal carbuncle; Scrofula; Spit blood; Epistaxis; Stranguria with blood; Edema; Ascites and cancer." Quanzhou book on Chinese herbal medicine " carries: " heat clearing away, detoxifcation, method wind, loose blood, circulation of qi promoting, diuretic, collateral dredging, removing blood stasis with potent drugs, pain relieving." the modern medicine study confirmation, Herba Scutellariae Barbatae has stronger antibacterial and phlegm-dispelling functions, and acute cellular type leukemia hemocyte is had significant inhibitory action, obviously improves the percentage rate of esterase positive cell in the peripheral blood lymphocyte, promotes delayed allergy.
Fructus Trichosanthis: sweet-bitter flavor; Cold in nature.Enter lung; The stomach warp.Lung moistening; Reduce phlegm; Eliminating stagnation; Intestine moistening.Cure mainly phlegm-heat cough; The thoracic obstruction; Blocked-up chest; The consumptive lung disease hemoptysis; Quench one's thirst; Jaundice; Constipation; Carbuncle from the beginning of." detailed outline " carries: " lung moistening is dry, pathogenic fire reducing, and the main thoracic obstruction is controlled cough, and the clearing away phlegm knot is logical hot and suffocating in the heart." modern medicine study confirms that the Fructus Trichosanthis master contains triterpene saponin, fatty oil, several amino acids and alkaloid, have eliminate the phlegm, the effect of coronary artery dilator, increase coronary flow, anti-hypoxia, blood fat reducing, the treatment for coronary heart disease has preferably curative effect clinically.
Radix Peucedani: bitter in the mouth; Hot; Cold nature.Return lung; Spleen; Liver Channel.Dispelling wind and heat pathogens; Lowering the adverse-rising QI to resolve phlegm.Cure mainly affection due to external wind and heat; The lung-heat phlegm stagnancy; The cough with asthma abundant expectoration; The expectorant Huang is sticky; Contrary lack of appetite; Chest and diaphragm is full vexed." Japan hanako materia medica " carries: " control all labor, lower all gas, antitussive, broken crux, whetting the appetite, logical the five internal organs, main cramp caused by acute vomiting and diarrhea, joint is unhappy, regurgitation, vomiting, asthma, all infantile malnutrition gas of children's." modern medicine study confirms, the intestinal that the Radix Peucedani ethanol extract can be significantly causes anti-acetylcholine and histamine shrinks, and constitutional and Secondary cases platelet aggregation are had strong inhibitory action, also has in addition the phlegm-dispelling functions of coronary artery dilator and increase respiratory tract juice.
Semen Armeniacae Amarum: bitter in the mouth; Warm in nature; Poisonous.Enter lung; Spleen; Large intestine channel.Expelling phlegm for arresting cough; Relieving asthma; Intestine moistening; Lower air to open numbness.Cure mainly the exogenous cough; Dyspnea with fullness of the chest; The cough due to dryness; The cold renal mass; Infantile convulsion; The thoracic obstruction; Stomachache due to dyspepsia; Metrorrhagia; Deaf; Infantile malnutrition with edema and abdominal distention; Damp and hot stranguria; Scabies; Sore throat; The dryness of the intestine constipation." property of medicine opinion " carries: " it is obstructed to control abdomen numbness, diaphoresis, main epidemic febrile disease.Control completely pain of spasm in the epigastrium, except the trusted subordinate is unhappy, treat the lung qi cough, dyspnea.Enter Radix Asparagi and fry in shallow oil, the profit cardiopulmonary.Can make soup with cheese, benefit profit information.The place i.e. moving cold air." the modern medicine study confirmation; Semen Armeniacae Amarum can effectively be controlled the content of cholesterol in human body; significantly reduce the initiation potential of heart disease and multiple chronic disease, has the effects such as lung moistening, cough-relieving, laxation, and the diseases such as dry cough without phlegm, chronic cough of deficiency lung are had certain mitigation.
Herba Houttuyniae: acrid in the mouth; Cold in nature.Enter liver; Lung meridian.Heat-clearing and toxic substances removing; Removing pus and relieving carbuncle; Inducing diuresis for treating stranguria syndrome.Cure mainly the lung abscess vomiting pus; The expectorant dyspnea of heat type is coughed; Hematodiarrhoea; Carbuncle sore tumefacting virus; Pyretic stranguria." Chinese herbal medicine handbook commonly used is carried: " eliminating inflammation and expelling toxin, inducing diuresis to remove edema.Control upper respiratory tract infection, lung abscess, urinary tract inflammation and other position suppurative inflammation." the modern medicine study confirmation; Herba Houttuyniae can strengthen the phagocytic activity of WBC; improve immunity of organisms; various microorganisms are all had inhibitory action, also has in addition significant antagonism, antiviral, diuresis, analgesia, antitussive, hemostasis, inhibition serous secretion, promotes tissue regeneration, calmness, anti-frightened acting on.
Herba Hedyotidis Diffusae: bitter in the mouth; Sweet; Cold in nature; Nontoxic.Enter the heart; Liver; Spleen; Large intestine channel.Heat-clearing and toxic substances removing; Dampness removing.Cure mainly dyspnea and cough due to lung-heat; Laryngopharynx swelling and pain; The intestinal carbuncle; The furuncle and phyma skin infection; The puckery pain of pyretic stranguria; Edema; Jaundice due to damp-heat; Cancerous protuberance." Quanzhou book on Chinese herbal medicine " carries: " heat clearing away dissipating blood stasis, eliminating carbuncle detoxifcation.Control ulcer sores, scrofula.Again can lung heat clearing fire, eliminating the pathogens from the lung heat.Control the lung-heat dyspnea with rapid and short breath, cough against uncomfortable in chest." the modern medicine study confirmation; Herba Hedyotidis Diffusae all has stronger inhibitory action to the tumor cell of acute lymphoblastic type, granulocyte type, monocyte type and chronic granulocyte type; can stimulate the reticuloendothelial system hypertrophy; strengthen the phagocyte vigor, staphylococcus aureus, state's Shigella flexneri, Bacillus typhi, bacillus pyocyaneus are all had inhibitory action.
The present invention compared with prior art has following beneficial effect:
Compatibility of the present invention is reasonable, for problems such as the deficiency of the spleen causing weakness of QI, lack of lung-YIN, the deficiency of YIN that cause pulmonary lesion are scorchingly hot, take qi-benefiting and spleen-strengthening drug as monarch, take the detoxifcation the lung moistening medicine as minister, for making, concoct superior take the nourishing YIN to lower pathogenic fire medicine as left, supplement spleen QI invigorating, nourishing YIN to lower pathogenic fire, clearing heat in the lung lung moistening, detoxifcation clears phlegm, through the clinical verification good absorbing effect, to the patients with lung cancer of lung tumors pathological changes and each period of expansion, significant curative effect is arranged.
The specific embodiment
Below in conjunction with specific embodiment the present invention is further elaborated.
Embodiment 1
The raw material of effective ingredient of the present invention forms and weight is:
Radix Asparagi 60g 57g Radix Ophiopogonis Fructus Schisandrae Chinensis 53g Rhizoma Phragmitis 48g
Bulbus Fritillariae Cirrhosae 46g Radix Adenophorae (Radix Glehniae) 43g Folium Ilicis Cornutae 40g Radix Astragali 36g
Rhizoma Atractylodis Macrocephalae 32g Rhizoma Curcumae 28g Herba Scutellariae Barbatae 25g Fructus Trichosanthis 23g
Radix Peucedani 19g Semen Armeniacae Amarum 17g Herba Houttuyniae 13g Herba Hedyotidis Diffusae 8g
The processing step of process for preparing medicine of the present invention is:
(1) Bulbus Fritillariae Cirrhosae, Rhizoma Curcumae, Semen Armeniacae Amarum are ground into powder after pulverizing, crossed 120 order fine powders, for subsequent use.
(2) Radix Astragali is mixed thoroughly with refined honey, with slow fire fry to the surface be glassy yellow and tack-free after, cool rear pulverizing and grind into powder, cross 120 order fine powders, for subsequent use.
(3) Radix Asparagi, Radix Ophiopogonis, Rhizoma Phragmitis, Radix Adenophorae (Radix Glehniae), the Rhizoma Atractylodis Macrocephalae, Herba Scutellariae Barbatae, Fructus Trichosanthis, Radix Peucedani, Herba Houttuyniae, Herba Hedyotidis Diffusae are put into container, add the water of six times of amounts, soak after 12～14 hours, get immersion; The water that adds again again four times of amounts in remaining medicinal residues soaked after 8～10 hours, got immersion; Merge twice gained immersion, heating evaporation is the ointment of relative density 1.15～1.20 under 60 ℃ of environment, and is for subsequent use.
(4) Fructus Schisandrae Chinensis, Folium Ilicis Cornutae are put into container, add the ethanol of triplication, soak after 4～6 hours, get immersion; The ethanol that adds again doubling dose in remaining medicinal residues soaked after 3～5 hours, got immersion; Merge twice gained immersion, heating evaporation is the ointment of relative density 1.10～1.15 under the room temperature environment, and is for subsequent use.
(5) with the fine powder of step (1), step (2) gained, the ointment that makes with step (3), step (4) mixes, and the rear lyophilizing that stirs is prepared as the tablet product.
Usage and dosage: adult every day 3 times, each 250～400mg, two hours after meal warm water delivery services, serious symptom person's four times a day, each 300～500mg takes at most 4g every day, and 7 days is a course for the treatment of, general 3～5 onsets course for the treatment of.
Embodiment 2
The raw material of effective ingredient of the present invention forms and weight is:
Radix Asparagi 55g 52g Radix Ophiopogonis Fructus Schisandrae Chinensis 50g Rhizoma Phragmitis 45g
Bulbus Fritillariae Cirrhosae 42g Radix Adenophorae (Radix Glehniae) 39g Folium Ilicis Cornutae 35g Radix Astragali 32g
Rhizoma Atractylodis Macrocephalae 28g Rhizoma Curcumae 25g Herba Scutellariae Barbatae 23g Fructus Trichosanthis 19g
Radix Peucedani 17g Semen Armeniacae Amarum 15g Herba Houttuyniae 10g Herba Hedyotidis Diffusae 7g
Process for preparing medicine processing step and the usage and dosage of present embodiment are identical with embodiment 1.
Embodiment 3
The raw material of effective ingredient of the present invention forms and weight is:
Radix Asparagi 50g 48g Radix Ophiopogonis Fructus Schisandrae Chinensis 43g Rhizoma Phragmitis 39g
Bulbus Fritillariae Cirrhosae 37g Radix Adenophorae (Radix Glehniae) 35g Folium Ilicis Cornutae 30g Radix Astragali 27g
Rhizoma Atractylodis Macrocephalae 25g Rhizoma Curcumae 22g Herba Scutellariae Barbatae 20g Fructus Trichosanthis 17g
Radix Peucedani 15g Semen Armeniacae Amarum 13g Herba Houttuyniae 8g Herba Hedyotidis Diffusae 6g
Process for preparing medicine processing step and the usage and dosage of present embodiment are identical with embodiment 1.
Clinical data:
Follow the tracks of the clinical treatment data show, medicine of the present invention has significant therapeutic effect to small cell lung cancer and Patients with Non-small-cell Lung, significantly control hematogenous metastasis and Carcinoma cell differentiation, clinical total effective rate is up to 87%, chemotherapy, radiotherapy, surgical intervention post-operative recovery effective percentage are reached more than 90%, be suitable for pulmonary carcinoma before, auxiliary treatment behind intermediate period treatment and the Radiotherapy chemotherapy.
Claims (4)
1. medicine that is used for the treatment of pulmonary carcinoma is characterized in that: the raw material of making described effective ingredient forms and parts by weight are:
35～55 parts of 40～60 parts of Rhizoma Phragmitiss of Radix Asparagi 45～60 parts of Fructus Schisandrae Chinensis, 45～65 parts of Radix Ophiopogonis
25～40 parts of 25～45 parts of Radixs Astragali of 30～50 parts of Folium Ilicis Cornutaes of 35～50 parts of Radix Adenophorae (Radix Glehniae) of Bulbus Fritillariae Cirrhosae
15～25 parts of 15～30 parts of Fructus Trichosanthis of 15～35 portions of Herba Scutellariae Barbataes of 20～35 parts of Rhizoma Curcumae of the Rhizoma Atractylodis Macrocephalae
5～10 parts of 5～15 parts of Herba Hedyotidis Diffusaes of 10～20 parts of Herba Houttuyniae of 10～25 parts of Semen Armeniacae Amarums of Radix Peucedani.
2. a kind of medicine that is used for the treatment of pulmonary carcinoma according to claim 1 is characterized in that: the raw material of making described effective ingredient forms and parts by weight are:
38～52 parts of 43～58 parts of Rhizoma Phragmitiss of Radix Asparagi 47～57 parts of Fructus Schisandrae Chinensis, 48～62 parts of Radix Ophiopogonis
27～37 parts of 28～42 parts of Radixs Astragali of 32～46 parts of Folium Ilicis Cornutaes of 37～47 parts of Radix Adenophorae (Radix Glehniae) of Bulbus Fritillariae Cirrhosae
16～22 parts of 17～28 parts of Fructus Trichosanthis of 18～32 portions of Herba Scutellariae Barbataes of 23～33 parts of Rhizoma Curcumae of the Rhizoma Atractylodis Macrocephalae
6～9 parts of 8～12 parts of Herba Hedyotidis Diffusaes of 12～18 parts of Herba Houttuyniae of 13～22 parts of Semen Armeniacae Amarums of Radix Peucedani.
3. a kind of medicine that is used for the treatment of pulmonary carcinoma according to claim 1 is characterized in that: the raw material of making described effective ingredient forms and parts by weight are:
45 parts of 50 parts of Rhizoma Phragmitiss of Radix Asparagi 52 parts of Fructus Schisandrae Chinensis, 55 parts of Radix Ophiopogonis
32 parts of 35 parts of Radixs Astragali of 38 parts of Folium Ilicis Cornutaes of 42 parts of Radix Adenophorae (Radix Glehniae) of Bulbus Fritillariae Cirrhosae
19 parts of 22 parts of Fructus Trichosanthis of 25 portions of Herba Scutellariae Barbataes of 28 parts of Rhizoma Curcumae of the Rhizoma Atractylodis Macrocephalae
8 parts of 10 parts of Herba Hedyotidis Diffusaes of 15 parts of Herba Houttuyniae of 17 parts of Semen Armeniacae Amarums of Radix Peucedani.
4. preparation method that is used for the treatment of the medicine of pulmonary carcinoma is characterized in that: comprise following processing step:
(1) Bulbus Fritillariae Cirrhosae, Rhizoma Curcumae, Semen Armeniacae Amarum are ground into powder after pulverizing, crossed 120 order fine powders, for subsequent use.
(2) Radix Astragali is mixed thoroughly with refined honey, with slow fire fry to the surface be glassy yellow and tack-free after, cool rear pulverizing and grind into powder, cross 120 order fine powders, for subsequent use.
(3) Radix Asparagi, Radix Ophiopogonis, Rhizoma Phragmitis, Radix Adenophorae (Radix Glehniae), the Rhizoma Atractylodis Macrocephalae, Herba Scutellariae Barbatae, Fructus Trichosanthis, Radix Peucedani, Herba Houttuyniae, Herba Hedyotidis Diffusae are put into container, add the water of six times of amounts, soak after 12～14 hours, get immersion; The water that adds again again four times of amounts in remaining medicinal residues soaked after 8～10 hours, got immersion; Merge twice gained immersion, heating evaporation is the ointment of relative density 1.15～1.20 under 60 ℃ of environment, and is for subsequent use.
(4) Fructus Schisandrae Chinensis, Folium Ilicis Cornutae are put into container, add the ethanol of triplication, soak after 4～6 hours, get immersion; The ethanol that adds again doubling dose in remaining medicinal residues soaked after 3～5 hours, got immersion; Merge twice gained immersion, heating evaporation is the ointment of relative density 1.10～1.15 under the room temperature environment, and is for subsequent use.
(5) with the fine powder of step (1), step (2) gained, the ointment that makes with step (3), step (4) mixes, and the rear lyophilizing that stirs is prepared as the tablet product.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103611093B (en) * | 2013-12-11 | 2015-10-28 | 东莞市东卓中天生物科技有限公司 | A kind of Chinese medicine composition for the treatment of pulmonary carcinoma |
| CN110537684A (en) * | 2019-04-23 | 2019-12-06 | 辽宁抗风竤生物医药科技有限责任公司 | Dietary therapy composition for treating lung cancer and preparation method thereof |
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2012
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103611093B (en) * | 2013-12-11 | 2015-10-28 | 东莞市东卓中天生物科技有限公司 | A kind of Chinese medicine composition for the treatment of pulmonary carcinoma |
| CN110537684A (en) * | 2019-04-23 | 2019-12-06 | 辽宁抗风竤生物医药科技有限责任公司 | Dietary therapy composition for treating lung cancer and preparation method thereof |
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Application publication date: 20130306 |