CN105456661A - Traditional Chinese medicine electuary for treating radiodermatitis and preparation method - Google Patents

Abstract

The invention discloses a traditional Chinese medicine electuary for treating radiodermatitis and a preparation method, and belongs to the field of traditional Chinese medicine. The traditional Chinese medicine electuary is prepared from leaves of broussonetia kazinoki sieb. et Zucc., manyinflorescenced sweetvetch roots, sansevieria trifasciata, roots of straight ladybell, roots of Amur ampelopsis, rhizoma atractylodis macrocephalae, radix ophiopogonis, licorice roots, mecodium microsorum Ching., radix codonopsis, australian cowplant roots or leaves, radix angelica sinensis, radix asparagi, roots of red-rooted salvia, all-grass of delavay pararuellia, korean pine seeds, common achyranthes herb, flos sophorae, glossy privet fruit, Chinese wolfberry fruit, radix pseudostellariae, david deer fat, Japanese pagodatree bark and Siberian saltbush fruit. According to the traditional Chinese medicine electuary, all the selected medicinal materials accord with the theory of monarch drugs, minister drugs, assistant drugs and guiding drugs, the drugs are used according to symptoms and pathogeny, the effects of tonifying the liver and kidney, replenishing Qi, enriching the blood, promoting blood circulation to remove blood stasis, clearing heat, removing toxicity, nourishing Yin, generating body fluid, removing swelling, relieving itching, closing sores, promoting tissue regeneration and moistening skin are achieved, the absorption effect is good, the curative effect is significant, toxic and side effects and clinical adverse reactions do not exist, and it is proved in clinic that the cure rate of the traditional Chinese medicine electuary to the radiodermatitis is high.

Description

A kind of instant particles as Chinese medicine and preparation method being used for the treatment of radiodermatitis

Art

The present invention relates to the field of Chinese medicines, particularly relate to a kind of instant particles as Chinese medicine and the preparation method that are used for the treatment of radiodermatitis.

Background technology

Radiotherapy is exactly radiotherapy, refers to eliminate focus with ray, and radiotherapy, as an important means for the treatment of malignant tumor, can produce better effects for many cancers.Radiodermatitis after radiation exposure, causes erythema, decortication, pruritus, pain through radiocurable tumor patient skin mucosa, even occurs blister, ulcer, and the symptom such as hemorrhage and downright bad of local skin may appear in severe patient.Result of study shows, and about have the tumor patient of 87% to occur above-mentioned symptom after radiotherapy, radiodermatitis has become modal radiotherapy infectious-related complication.

Radiodermatitis infringement occur sooner or later and weight and radioactive character, dosage and patient individual variation relevant.Current doctor trained in Western medicine there is no specific short for primary disease, clinical in put prevention first, and avoids a large amount of when first should note radiotherapy, as dermatitis occurs for oneself, and Ying Tingzhao, and regular follow-up is observed, and has regular physical checkups, avoids radioactive substance as far as possible and give symptomatic treatment.The western medical treatment of radiodermatitis uses vitamins, glucocorticoids, Superoxides dismutase, recombinant human epidermal growth factor, antibiotics, sedation-analgesia class medicine to carry out symptomatic treatment usually, and is aided with physiotherapy and the routine care measures such as hydrophilic gel, millimeter-wave irradiation, high flow capacity oxygen therapy.Although western medicine primary disease instant effect, cures the symptoms, not the disease, in radiation therapy process repeatedly, primary disease easily occurs repeatedly, and after patient stops radiotherapy, treatment cycle is longer, to the great misery that brings of patient, also delays radiocurable progress.

According to tcm theory, think that lonizing radiation are " burning hot poison evil ", act on human body and cause pyretic toxicity to cross Sheng, body fluid is impaired, and then bright Tianjin sparkles blood, yin-damaging and Qi consuming, and heat accumulates the flesh natural fibre line of meat, and impairment of YIN is burnt network, and causes the diseases such as desquamation, erythema, pruritus, ulcer.The present invention suits the remedy to the case according to the cause of disease, there is effect of liver and kidney tonifying, vigorate qi and replenish the blood, blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing, YIN nourishing and the production of body fluid promoting, repellent antipruritic, expelling pus and promoting granulation, moist skin, good absorbing effect, evident in efficacy, the healing of wound surface can be accelerated, alleviate patient suffering, alleviate radiotherapy side reaction, ensure radiocurablely to carry out smoothly, have no side effect and clinical adverse, higher to radiodermatitis cure rate through clinical verification.

Summary of the invention

The invention provides a kind of instant particles as Chinese medicine and the preparation method that are used for the treatment of radiodermatitis, there is effect of liver and kidney tonifying, vigorate qi and replenish the blood, blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing, YIN nourishing and the production of body fluid promoting, repellent antipruritic, expelling pus and promoting granulation, moist skin, cure the disease and ask source treating both the principal and secondary aspects of a disease, for radiodermatitis, there is good curative effect.

For achieving the above object, technical scheme of the present invention is implemented as follows:

Be used for the treatment of an instant particles as Chinese medicine for radiodermatitis, raw material composition and the parts by weight of making described effective ingredient are:

Little leaf of Broussonetia papyrifera (L.) L.Her.ex Vent. 70 ~ 85 parts, Radix Hedysari 66 ~ 82 parts, Folium Sansevieriae Trifasclatae 63 ~ 78 parts, Radix Adenophorae (Radix Glehniae) 60 ~ 74 parts,

Radix ampelopsis brevipedunculatae 56 ~ 70 parts, the Rhizoma Atractylodis Macrocephalae 53 ~ 67 parts, Radix Ophiopogonis 50 ~ 63 parts, 46 ~ 60 parts, Radix Glycyrrhizae,

Fruitlet Mecodium badium (Hook. Et Grev.) Cop. 43 ~ 56 parts, Radix Codonopsis 40 ~ 53 parts, Radix Gymnematis Sylvestris 37 ~ 50 parts, Radix Angelicae Sinensis 34 ~ 47 parts,

Radix Asparagi 31 ~ 44 parts, Radix Salviae Miltiorrhizae 28 ~ 41 parts, Herb Pararuelliae delavayanae 25 ~ 38 parts, Semen pini koraiensis 22 ~ 35 parts,

Radix achyranthis asperae (Herba Achyranthis Asperae) 19 ~ 32 parts, 16 ~ 29 parts, Flos Sophorae, Fructus Ligustri Lucidi 13 ~ 26 parts, Fructus Lycii 10 ~ 23 parts,

Rod rod grass 7 ~ 20 parts, Adeps Elaphuri davidiani 5 ~ 17 parts, Cortex sophorae 3 ~ 14 parts, Fructus Atriplicis Sibiricae 1 ~ 10 part.

Raw material composition and the parts by weight of making described effective ingredient are:

Little leaf of Broussonetia papyrifera (L.) L.Her.ex Vent. 74 ~ 82 parts, Radix Hedysari 70 ~ 78 parts, Folium Sansevieriae Trifasclatae 66 ~ 75 parts, Radix Adenophorae (Radix Glehniae) 63 ~ 70 parts,

Radix ampelopsis brevipedunculatae 60 ~ 67 parts, the Rhizoma Atractylodis Macrocephalae 56 ~ 64 parts, Radix Ophiopogonis 53 ~ 60 parts, 50 ~ 56 parts, Radix Glycyrrhizae,

Fruitlet Mecodium badium (Hook. Et Grev.) Cop. 46 ~ 53 parts, Radix Codonopsis 43 ~ 50 parts, Radix Gymnematis Sylvestris 40 ~ 47 parts, Radix Angelicae Sinensis 37 ~ 44 parts,

Radix Asparagi 34 ~ 41 parts, Radix Salviae Miltiorrhizae 31 ~ 38 parts, Herb Pararuelliae delavayanae 28 ~ 35 parts, Semen pini koraiensis 25 ~ 32 parts,

Radix achyranthis asperae (Herba Achyranthis Asperae) 22 ~ 29 parts, 19 ~ 26 parts, Flos Sophorae, Fructus Ligustri Lucidi 16 ~ 23 parts, Fructus Lycii 13 ~ 20 parts,

Rod rod grass 10 ~ 17 parts, Adeps Elaphuri davidiani 8 ~ 14 parts, Cortex sophorae 5 ~ 12 parts, Fructus Atriplicis Sibiricae 2 ~ 7 parts.

Raw material composition and the parts by weight of making described effective ingredient are:

Little leaf of Broussonetia papyrifera (L.) L.Her.ex Vent. 78 parts, Radix Hedysari 74 parts, Folium Sansevieriae Trifasclatae 71 parts, Radix Adenophorae (Radix Glehniae) 67 parts,

Radix ampelopsis brevipedunculatae 64 parts, the Rhizoma Atractylodis Macrocephalae 60 parts, Radix Ophiopogonis 56 parts, 53 parts, Radix Glycyrrhizae,

Fruitlet Mecodium badium (Hook. Et Grev.) Cop. 50 parts, Radix Codonopsis 47 parts, Radix Gymnematis Sylvestris 44 parts, Radix Angelicae Sinensis 41 parts,

Radix Asparagi 37 parts, Radix Salviae Miltiorrhizae 34 parts, Herb Pararuelliae delavayanae 31 parts, Semen pini koraiensis 28 parts,

Radix achyranthis asperae (Herba Achyranthis Asperae) 25 parts, 23 parts, Flos Sophorae, Fructus Ligustri Lucidi 20 parts, Fructus Lycii 17 parts,

Rod rod grass 14 parts, Adeps Elaphuri davidiani 11 parts, Cortex sophorae 8 parts, Fructus Atriplicis Sibiricae 4 parts.

Be used for the treatment of a preparation method for the instant particles as Chinese medicine of radiodermatitis, comprise following processing step:

(1) little leaf of Broussonetia papyrifera (L.) L.Her.ex Vent., Folium Sansevieriae Trifasclatae, Radix Adenophorae (Radix Glehniae), Radix ampelopsis brevipedunculatae, the Rhizoma Atractylodis Macrocephalae, Radix Ophiopogonis, fruitlet Mecodium badium (Hook. Et Grev.) Cop., Radix Gymnematis Sylvestris, Radix Asparagi, Herb Pararuelliae delavayanae, Semen pini koraiensis, Radix achyranthis asperae (Herba Achyranthis Asperae), Fructus Ligustri Lucidi, rod rod grass, Cortex sophorae, Fructus Atriplicis Sibiricae are cleaned, dried rear mix homogeneously, put into container, add the water of 6 ~ 8 times amount in a reservoir, heated and boiled 2 ~ 3 hours, gets immersion after cooling; In remaining medicinal residues, add the water of 4 ~ 6 times amount again, heated and boiled 1 ~ 2 hour, gets immersion after cooling; Merge twice gained immersion, heating, evaporation and concentration is the thick paste of relative density 1.15 ~ 1.25, for subsequent use;

(2) Radix Angelicae Sinensis, Fructus Lycii are put into container, add the shao-hsing rice wine of 3 ~ 5 times amount, cool after boiling, continue immersion 3 ~ 5 hours, get immersion; In remaining medicinal residues, add the shao-hsing rice wine of 2 ~ 4 times amount again, put after boiling and dry in the air, continue immersion 2 ~ 4 hours, get immersion; Merge twice gained immersion, add and steam the thick paste that evaporation and concentration is relative density 1.10 ~ 1.20, for subsequent use;

(3) clean Radix Hedysari sheet is added cooked Mel and a little boiled water, mixes thoroughly slightly vexed, put in pot fry to yellow and tack-free time, take out and dry in the air cool, pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;

(4) get clean Radix Glycyrrhizae tabellae, add cooked Mel and a little boiled water, slightly vexed after mixing thoroughly, put in parch container, slow fire is fried to buff, and take out time tack-free, cool, pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;

(5) be placed in the pot of heating by wheat bran, when playing cigarette to pot, add Radix Codonopsis sheet, stir to buff, take out sieve and remove wheat bran, cool, pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;

(6) get Radix Salviae Miltiorrhizae Tabellae, add yellow wine and mix thoroughly, moistening is to saturating, and put in pot, use slow fire fried dry, taking-up cools, and pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;

(7) get clean Flos Sophorae, fry to surperficial buff by frying method, taking-up cools, and pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;

(8) Adeps Elaphuri davidiani is added a small amount of boiled water to mix thoroughly, then water proof is heated to Adeps Elaphuri davidiani and dissolves completely, obtains medicinal liquid, for subsequent use.

(9) by the thick paste of step (1), step (2) gained, mix with the fine powder of gained in step (3), step (4), step (5), step (6), step (7) and the medicinal liquid of the middle gained of step (8), add adjuvant sucrose and dextrin mix homogeneously makes granule, after drying, granulate, be packaged into the instant particles as Chinese medicine of every bag of 10g.

The property of medicine of the present invention's Chinese medicine used is as follows:

Little leaf of Broussonetia papyrifera (L.) L.Her.ex Vent.: lightly seasoned; Cool in nature.Heat-clearing and toxic substances removing; Dispelling wind for relieving itching; Sore is stopped blooding.Cure mainly dysentery; Neurodermatitis; Scabies; Furuncle and phyma; Knife injury is hemorrhage.

Radix Hedysari: sweet in the mouth; Warm in nature.Return lung, spleen channel.Invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Cure mainly the deficiency of vital energy weak; Anorexia and loose stool; Chronic diarrhea proctoptosis; Have blood in stool; Metrorrhagia; Exterior deficiency spontaneous perspiration; Deficiency of vital energy edema; Blood deficiency and yellow complexion; The routed difficulty of carbuncle difficulty is held back.

Folium Sansevieriae Trifasclatae: sour in the mouth; Cool in nature.Heat-clearing and toxic substances removing; Removing the necrotic tissue and promoting granulation.Cure mainly flu; Cough due to lung-heat; Sore swollen toxin; Traumatic injury, venom; Burn and scald." Guangxi Chinese herbal medicine ": heat-clearing and toxic substances removing, removing the necrotic tissue and promoting granulation.Cure cold cough, bronchitis, traumatic injury, carbuncle pyogenic infections from tumour or sore, venom.

Radix Adenophorae (Radix Glehniae): sweet in the mouth; Micro-hardship; Cold nature.Return lung; Stomach warp.Replenishing YIN and removing heat; Moistening the lung and resolving phlegm; Reinforcing stomach reg fluid.Cure mainly deficiency of YIN chronic cough; Consumptive disease is coughed expectorant blood; Cough caused by dryness expectorant is few; Deficiency-heat sore throat; Tianjin wound is thirsty.Compendium of Material Medica is carried: " Radix Adenophorae (Radix Glehniae) is sweet light and cold, and its body is gently empty, special tonifying the lung gas, thus strengthening the spleen and kidney, therefore gold can should it by fire gram person.YANG invigorating and raw cloudy, nourishing YIN and sun processed, must debate also." modern medicine study confirms; Radix Adenophorae (Radix Glehniae) contains volatile oil, coumarin, starch, alkaloid, triterpenic acid, stigmasterol, β-each sterol; improve T cell ratio; improve lymhocyte transformation rate, leukocyte increasing, strengthens macrophage function; extend antibody life period; have antipyretic, ease pain, eliminate the phlegm, function of relievining asthma, strengthen the immunologic function of body fluid and cell, have protection and inhibitory action to irritability and Drug gastric ulcer.

Radix ampelopsis brevipedunculatae: acrid in the mouth; Bitter; Cool in nature.Return lung; Liver; Large intestine channel.Heat-clearing and toxic substances removing; Expelling wind and removing dampness; Blood circulation promoting and dispersing pathogen accumulation.Cure mainly pain in the lung vomiting pus; Pulmonary tuberculosis is spat blood; Rheumatic arthralgia; Traumatic injury; Carbuncle sore tumefacting virus; Scrofula; Cancerous protuberance." Zhejiang conventional medical herbs among the people ": removing blood stasis and activating blood flow, anti-inflammation, hemostasis.

The Rhizoma Atractylodis Macrocephalae: bitter in the mouth; Sweet; Warm in nature.Return spleen; Stomach warp.Invigorating the spleen and benefiting QI; Dampness diuretic; Hidroschesis; Antiabortive.Cure mainly deficiency-weakness of spleen-QI; Spiritlessness and weakness; Lack of appetite abdominal distention; Large loose stool is thin; Fluid-retention stagnating in the interior; Dysuria; Edema; Dizziness due to fluid-retention; Arthralgia chiefly caused by damp pathogen is ached; Spontaneous sweating due to deficiency of QI; Frequent fetal movement." herbal classic is met former " carries: " art, raw with there being dehumidifying benefit dry, expectorant diuretic, controls anemofrigid-damp arthralgia, dead flesh convulsion subcutaneous ulcer, blood between loose waist umbilicus, and chong channel is disease, the merit of inverse gas pain in the abdomen; Make ripe, have and middle QI invigorating, slake thirst and help produce saliva, hidroschesis heat extraction, enters diet, antiabortive effect." modern medicine study confirms, the Rhizoma Atractylodis Macrocephalae has diuresis, blood sugar lowering, strong, anticoagulation, antitumor, antibacterial, the effect that promotes hemopoietic and protein synthesis.

Radix Ophiopogonis: sweet in the mouth; Micro-hardship; Cold in nature.Return lung; Stomach; Heart channel.Nourishing YIN and moistening the lung; Reinforcing stomach reg fluid; Clear away heart-fire relieving restlessness.Cure mainly dryness of the lung dry cough; Lung abscess; Deficiency of YIN chronic cough; Tianjin wound is thirsty; Quench one's thirst; Vexed insomnia; Have sore throat; Dryness of the intestine constipation; Heat in blood tells nosebleed." Mingyi Bielu ": treat heavy sensation of the body icteric sclera, rami cardiaci inferiores is full, asthenia exopathogenic heat, xerostomia excessive thirst, anti-nausea, more flaccidity falls, and reinforcing YIN-essence benefit essence, during rapid digestion of food is adjusted, protects god, determine lung qi, settling five organs, makes us fertile strong.Modern medicine study proves: modern pharmacological research also shows, Radix Ophiopogonis is mainly containing dwarf lilyturf glycosides, steroidal saponin, alkaloid, sitosterol, glucose, aminoacid, vitamin etc., there is resisting fatigue, scavenging free radicals, raising cellular immune function and hypoglycemic effect, in addition, Radix Ophiopogonis have calmness, hypnosis, resist myocardial ischemia, the effect such as arrhythmia, antitumor.

Radix Glycyrrhizae: sweet in the mouth; Property is put down.GUIXIN; Lung; Spleen; Stomach warp.Invigorating the spleen and replenishing QI; Heat-clearing and toxic substances removing; Expelling phlegm for arresting cough; Relieving spasm to stop pain; Coordinating the actions of various ingredients in a prescription.Cure mainly weakness of the spleen and stomach; Fatigue and weakness; Shortness of breath and palpitation; Cough with copious phlegm; Gastral cavity abdomen four muscle spasm of the leg and foot pain; Carbuncle sore tumefacting virus; Cushion toxicity.Compendium of Material Medica is carried: " in all medicines, Radix Glycyrrhizae is monarch.Control 72 kinds of mammary calculus poison, draft is malicious by every means to separate 1,002, is in harmonious proportion from medicine and gains merit." modern medicine study confirmation; Radix Glycyrrhizae has stronger Detoxication; also have antiulcer, anti-inflammatory, spasmolytic antitussive, blood pressure lowering, blood fat reducing, antitumaous effect; be widely used in the diseases such as treatment pharyngolaryngitis, laryngitis, tracheitis, bronchitis, asthma, cough, hemoptysis, have anti-gastric-ulcer, gastritis effect in addition.

Fruitlet Mecodium badium (Hook. Et Grev.) Cop.: mildly bitter flavor; Cool in nature.Heat-clearing and toxic substances removing; Expelling pus and promoting granulation.Cure mainly carbuncle furuncle and phyma poison; Burn due to hot liquid or fire.

Radix Codonopsis: sweet in the mouth; Property is put down.Return spleen; Lung meridian.Strengthening the spleen and tonifying the lung; Supplementing QI for promoting the production of body fluid.Cure mainly weakness of the spleen and stomach; Anorexia and loose stool; Limbs fatigue; The deficiency of the lung is breathed with cough; To breathe hard spontaneous perspiration; The all cards of deficiency of both QI and blood." moral joins book on Chinese herbal medicine " carries: " lung heat clearing gold, invigorating primordial QI, opens sound, helps biceps." modern medicine study confirms; Radix Codonopsis energy Gastrointestinal motility adjustment, antiulcer, enhancing immunologic function; on excited and suppress two kinds of nervous process to have impact, can raise erythrocyte, hemoglobin, reticulocyte, also have the effect of slow down aging and antioxidation, radioprotective, blood pressure lowering.

Radix Gymnematis Sylvestris: bitter in the mouth; Property is put down.GUIXIN; Liver; Spleen channel.Clearing away heat and cooling blood; Evacuation of pus is subsided a swelling; Expelling pus and promoting granulation.Cure mainly rheumatic arthralgia; Laryngopharynx swelling and pain; Scrofula; Acute mastitis; Furuncle; Eczema; Innominate toxic swelling; Venom." practical Chinese herbal medicine ": root, subduing swelling and detoxicating, clearing away heat and cooling blood.Control multiple abscess, deep abscess, mastitis, carbuncle pyogenic infections from tumour or sore.

Radix Angelicae Sinensis: sweet in the mouth; Pungent; Warm in nature.Return liver, the heart, spleen channel.Enrich blood and invigorate blood circulation; Menstruction regulating and pain relieving; Loosening bowel to relieve constipation.Cure mainly blood deficiency and yellow complexion; Dizzy cardiopalmus; Asthenia cold abdominalgia; Rheumatic arthralgia; Injury from falling down; Ulcer sores." book on Chinese herbal medicine is just " carries: " its sweet in the mouth and weigh, therefore specially can enrich blood, its gas is light and pungent, therefore again can promoting the circulation of blood, can support nutrition blood, QI invigorating spermatogenesis, settling five organs, strong body, beneficial mind, all tangible deficient diseases, nothing unsuitable." modern medicine study confirmation, Radix Angelicae Sinensis has antibacterial, antiinflammation, has inhibitory action to chronic articular rheumatism acute attack.

Radix Asparagi: sweet in the mouth; Bitter; Cold in nature.Enter lung; Kidney channel.Nourshing Yin and drynsessmoistening prescription, YIN nourishing and the production of body fluid promoting, lung moistening clear away heart-fire, cough-relieving of relieving inflammation or internal heat.Cure mainly cough caused by dryness-heat; Deficiency of YIN chronic cough; Consumption of YIN caused by febrile disease; Interior-heat is quenched one's thirst; Dryness of the intestine constipation; Laryngopharynx swelling and pain." Japan hanako materia medica ": relieving palpitation, moistening five ZANG-organs, beneficial skin, improving healthy complexion, mends five kinds of strain and seven kinds of impairment, controls lung qi and cough, expectorant, migratory arthralgia pyretic toxicity, urticaria, unhappy haematemesis.Modern medicine study confirms, Radix Asparagi has antibacterial, antineoplastic action, and has and raise peripheral leukocytes, strengthen reticuloendothelial system phagocytic function, be conducive to antibody and formed, strengthen the functions such as humoral immunity.

Radix Salviae Miltiorrhizae: bitter in the mouth; Cold nature; Nontoxic.Enter the heart; Liver Channel.Blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, clear away heart-fire relieving restlessness, removing heat from blood eliminating carbuncle.For obstruction of qi in the chest and cardialgia, gastral cavity abdomen hypochondriac pain, abdominal mass abdominal mass is gathered, pyretic arthralgia pain, dysphoria and insomnia, menoxenia, and dysmenorrhea amenorrhea, skin infection swells and ache." herbal classic " carries: " main trusted subordinate's pathogen, borborygmus are faint as leaked water, and cold and heat gather; Broken disease, except abdominal mass, stops stuffy sensation with restlessness, QI invigorating." modern medicine study confirms; Radix Salviae Miltiorrhizae has anti-inflammatory analgetic, coronary artery dilator, improves myocardial ischemia situation, blood pressure lowering, blood sugar lowering, blood fat reducing, protect the liver, antibacterial and promote the effect of reparation and regeneration of tissue, Radix Salviae Miltiorrhizae also to have anti-platelet aggregation, reduce blood viscosity and the function of blood coagulation system inside and outside regulating.

Herb Pararuelliae delavayanae: mildly bitter flavor; Pungent; Cool in nature.Heat-clearing and toxic substances removing; Dissipating blood stasis for subsidence of swelling.Cure mainly cough due to lung-heat; Laryngopharynx swelling and pain; Mumps; Scrofula; Carbuncle sore tumefacting virus; Injury and bone fracture; Trauma infection contamination." choosing of Yunnan Chinese herbal medicine ": antiinflammatory is drawn out pus by applying a plaster to the affected part, granulation promoting, dissipating blood stasis tissue regeneration promoting, parasite killing.Control acute suppurative tonsillitis, pneumonia, sore abscess, the raw maggot of wound infection.

Semen pini koraiensis: sweet in the mouth; Slightly warm in nature.Return liver; Lung; Large intestine channel.Moisturize, nourish blood, dispel the wind.Cure mainly dryness of the lung dry cough, stool constipation due to insufficiency, all dizziness due to wind, joint wind, migratory arthralgia.And have moist skin, apply the function of Rong Maofa." Japan hanako materia medica ": by migratory arthralgia cold, weakness with emaciation weak breath, tonifying for the deficiency, profit skin, fertile the five internal organs.

Radix achyranthis asperae (Herba Achyranthis Asperae): bitter in the mouth; Acid; Cold nature.Return liver; Lung; Urinary bladder channel.Blood circulation promoting and blood stasis dispelling; Inducing diuresis for treating stranguria syndrome; Clearing away heat and expelling pathogen in the exterior.Cure mainly amenorrhea; Dysmenorrhea; Menoxenia; Traumatic injury; Rheumatic arthritis; Gonorrhea; Edema; Damp-heat vaginal discharge, fever caused by exogenous pathogens; Malaria; Pharyngalgia; Furuncle carbuncle." conventional Chinese herbal medicine handbook ": heat clearing away, diuretic, strong muscle, loose blood.Cure cold heating, and heat of a specified duration is not moved back, rheumatic arthritis, lumbago and skelalgia, laryngalgia, hypertension, oedema due to nephritis.

Flos Sophorae: bitter in the mouth; Cold nature.Enter liver; Lung; The heart; Large intestine channel.Cooling blood for hemostasis; Purging liver-fire.Cure mainly discharging fresh blood stool; Hemorrhoid hematochezia; Dysentery; Hematuria; Stranguria with blood; Metrorrhagia; Spit blood; Epistaxis; Liver-heat is had a headache; Conjunctival congestion and swelling pain; Carbuncle skin infection." book on Chinese herbal medicine just " carries: " cool large intestine kills infantile malnutrition worm.Control skin sore, erosion of vulva pruritus due to damp pathogen, anal fistula, separate Fructus Myricae rubrae malignant boil, primary sore volt poison." modern medicine study confirms; Flos Sophorae has antiinflammatory, spasmolytic, antiulcer, reduces blood pressure, edema and antibacterial action; the composition globulariacitrin in Flos Sophorae and glycoside unit Quercetin thereof can keep the normal resistance of blood capillary; reduce vascular permeability, can make because fragility increases that hemorrhage blood capillary recovers normal elasticity.

Fructus Ligustri Lucidi: bitter in the mouth; Cool in nature.Return liver; Kidney channel.Tonifying liver kidney yin, crow must improving eyesight.Cure mainly the hepatic and renal YIN deficiency; Soreness of waist tinnitus; Early whitening of beard and hair; Unseeing; Fever due to yin deficiency; Gastropathy and gout and hyperuricemia." book on Chinese herbal medicine is new again ": replenishing YIN to strengthen the kidney, QI invigorating soothing liver-QI.Control lumbago and skelalgia, stimulate the menstrual flow and blood.Modern medicine study proves, Fructus Ligustri Lucidi has blood fat reducing, atherosclerosis, heart tonifying, diuresis, cough-relieving, cathartic, antibacterial and hepatoprotective effect, peripheral leukocytes can be improved, strengthen reticuloendothelial system phagocytic activity, there is the effect strengthening cellular immunization and humoral immunization, there is rising effect to the leukopenia caused because of chemotherapy or radiotherapy, the growth of some transplanted tumor of animal can be suppressed.

Fructus Lycii: sweet in the mouth; Property is put down.Return liver; Kidney; Lung meridian.Nourishing the liver; Nourishing kidney; Lung moistening.Cure mainly caused by liver and kidney deficiency; Have a dizzy spell; Visual one clear; Soreness of the waist and knees; The expensive essence of sexual impotence; Cough due to consumptive disease; To quench one's thirst taking fluids profusely." book on Chinese herbal medicine just " carries: " improve visual and auditory acuity, adds the solid marrow of essence, strengthen the muscle and bone, and kind benefit impairment caused by overstrain, especially only quenches one's thirst." modern medicine study confirm, Fructus Lycii scalable body's immunity, can effectively Tumor suppression grow and cell mutation, there is the effect of the aspect such as slow down aging, anti-fatty liver, adjusting blood lipid and blood glucose, promotion hemopoietic function.

Rod rod grass: sweet in the mouth; Bitter; Slightly warm in nature.Tonifying the lung; Spleen invigorating; YIN nourishing and the production of body fluid promoting.Cure mainly cough due to deficiency of the lung; Insufficiency of the spleen lack of appetite; Cardiopalmus spontaneous perspiration; Tired out weak; Xerostomia.

Adeps Elaphuri davidiani: sweet in the mouth; Pungent; Warm in nature.GUIXIN; Liver Channel.Promoting blood circulation; Cold-dispelling; Profit skin; Removing toxic substances.Cure mainly anemofrigid-damp arthralgia; Extremity are arrested slow; Women's head-ornaments swelling due to wind; Malignant boil carbuncle; Skin ulcer of looking unfamiliar bleb." herbal classic ": main carbuncle, malignant boil, dead flesh, cold wind arthralgia chiefly caused by damp pathogen, extremity are arrested and slow not to be received, and public attention swells gas, logical pancreas reason.

Cortex sophorae: bitter in the mouth; Property is put down.Return lung; The heart; Liver; Large intestine channel.Expelling wind and removing dampness; Expelling pus and promoting granulation; Subduing swelling and detoxicating.Cure mainly in outside ailment said due to cold or exposure; Orthotonus; Numbness of the skin; Calentura aphtha; Ulcerative gingivitis; Sore throat; Discharging fresh blood stool; Cellulitis; Hemorrhoid; Ulcer sores; Pudendum eczema; Burn due to hot liquid or fire." not Lu ": main rotten skin ulcer.

Fructus Atriplicis Sibiricae: bitter in the mouth; Property is put down.Return lung; Liver Channel.Liver heat removing and eyesight improving; Dispelling wind for relieving itching; Promoting blood circulation and detumescence; Lactogenesis.Cure mainly conjunctival congestion and swelling pain; Headache; Dizzy; Cough with dyspnea; Sore throat; Rubella; Skin carcinoma is itched; Toxic swelling; Milk is not smooth." soft science in China medicinal plants ": suppressing the hyperactive liver improving eyesight.Control E mass resulting from the blood stasis knot, headache, cough with dyspnea, skin pruritus due to wind pathogen, sore throat, skin ulcer is itched, toxic swelling.

The present invention compared with prior art, has following beneficial effect:

The present invention selects medical material monarch, minister, a left side, makes all reasons all standby, the property of medicine is suitable mutually auxiliary mutually, suit the remedy to the case for the cause of disease, there is effect of liver and kidney tonifying, vigorate qi and replenish the blood, blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing, YIN nourishing and the production of body fluid promoting, repellent antipruritic, expelling pus and promoting granulation, moist skin, good absorbing effect, evident in efficacy, have no side effect and clinical adverse, higher to radiodermatitis cure rate through clinical verification.

Detailed description of the invention

Below in conjunction with specific embodiment, the present invention is further elaborated.

Embodiment 1

The raw material composition of effective ingredient of the present invention and weight are:

Little leaf of Broussonetia papyrifera (L.) L.Her.ex Vent. 70 ~ 85g, Radix Hedysari 66 ~ 82g, Folium Sansevieriae Trifasclatae 63 ~ 78g, Radix Adenophorae (Radix Glehniae) 60 ~ 74g,

Radix ampelopsis brevipedunculatae 56 ~ 70g, the Rhizoma Atractylodis Macrocephalae 53 ~ 67g, Radix Ophiopogonis 50 ~ 63g, Radix Glycyrrhizae 46 ~ 60g,

Fruitlet Mecodium badium (Hook. Et Grev.) Cop. 43 ~ 56g, Radix Codonopsis 40 ~ 53g, Radix Gymnematis Sylvestris 37 ~ 50g, Radix Angelicae Sinensis 34 ~ 47g,

Radix Asparagi 31 ~ 44g, Radix Salviae Miltiorrhizae 28 ~ 41g, Herb Pararuelliae delavayanae 25 ~ 38g, Semen pini koraiensis 22 ~ 35g,

Radix achyranthis asperae (Herba Achyranthis Asperae) 19 ~ 32g, Flos Sophorae 16 ~ 29g, Fructus Ligustri Lucidi 13 ~ 26g, Fructus Lycii 10 ~ 23g,

Rod rod grass 7 ~ 20g, Adeps Elaphuri davidiani 5 ~ 17g, Cortex sophorae 3 ~ 14g, Fructus Atriplicis Sibiricae 1 ~ 10g.

The processing step of process for preparing medicine of the present invention is:

(1) little leaf of Broussonetia papyrifera (L.) L.Her.ex Vent., Folium Sansevieriae Trifasclatae, Radix Adenophorae (Radix Glehniae), Radix ampelopsis brevipedunculatae, the Rhizoma Atractylodis Macrocephalae, Radix Ophiopogonis, fruitlet Mecodium badium (Hook. Et Grev.) Cop., Radix Gymnematis Sylvestris, Radix Asparagi, Herb Pararuelliae delavayanae, Semen pini koraiensis, Radix achyranthis asperae (Herba Achyranthis Asperae), Fructus Ligustri Lucidi, rod rod grass, Cortex sophorae, Fructus Atriplicis Sibiricae are cleaned, dried rear mix homogeneously, put into container, add the water of 6 ~ 8 times amount in a reservoir, heated and boiled 2 ~ 3 hours, gets immersion after cooling; In remaining medicinal residues, add the water of 4 ~ 6 times amount again, heated and boiled 1 ~ 2 hour, gets immersion after cooling; Merge twice gained immersion, heating, evaporation and concentration is the thick paste of relative density 1.15 ~ 1.25, for subsequent use;

(2) Radix Angelicae Sinensis, Fructus Lycii are put into container, add the shao-hsing rice wine of 3 ~ 5 times amount, cool after boiling, continue immersion 3 ~ 5 hours, get immersion; In remaining medicinal residues, add the shao-hsing rice wine of 2 ~ 4 times amount again, put after boiling and dry in the air, continue immersion 2 ~ 4 hours, get immersion; Merge twice gained immersion, add and steam the thick paste that evaporation and concentration is relative density 1.10 ~ 1.20, for subsequent use;

(3) clean Radix Hedysari sheet is added cooked Mel and a little boiled water, mixes thoroughly slightly vexed, put in pot fry to yellow and tack-free time, take out and dry in the air cool, pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;

(4) get clean Radix Glycyrrhizae tabellae, add cooked Mel and a little boiled water, slightly vexed after mixing thoroughly, put in parch container, slow fire is fried to buff, and take out time tack-free, cool, pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;

(5) be placed in the pot of heating by wheat bran, when playing cigarette to pot, add Radix Codonopsis sheet, stir to buff, take out sieve and remove wheat bran, cool, pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;

(6) get Radix Salviae Miltiorrhizae Tabellae, add yellow wine and mix thoroughly, moistening is to saturating, and put in pot, use slow fire fried dry, taking-up cools, and pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;

(7) get clean Flos Sophorae, fry to surperficial buff by frying method, taking-up cools, and pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;

(8) Adeps Elaphuri davidiani is added a small amount of boiled water to mix thoroughly, then water proof is heated to Adeps Elaphuri davidiani and dissolves completely, obtains medicinal liquid, for subsequent use.

(9) by the thick paste of step (1), step (2) gained, mix with the fine powder of gained in step (3), step (4), step (5), step (6), step (7) and the medicinal liquid of the middle gained of step (8), add adjuvant sucrose and dextrin mix homogeneously makes granule, after drying, granulate, be packaged into the instant particles as Chinese medicine of every bag of 10g.

Usage and dosage: each 1 bag of every day 3 times, half an hour ante cibum takes after mixing it with water with boiled water 10 days is 1 course for the treatment of.Embodiment 2

The raw material composition of effective ingredient of the present invention and weight are:

Little leaf of Broussonetia papyrifera (L.) L.Her.ex Vent. 74 ~ 82g, Radix Hedysari 70 ~ 78g, Folium Sansevieriae Trifasclatae 66 ~ 75g, Radix Adenophorae (Radix Glehniae) 63 ~ 70g,

Radix ampelopsis brevipedunculatae 60 ~ 67g, the Rhizoma Atractylodis Macrocephalae 56 ~ 64g, Radix Ophiopogonis 53 ~ 60g, Radix Glycyrrhizae 50 ~ 56g,

Fruitlet Mecodium badium (Hook. Et Grev.) Cop. 46 ~ 53g, Radix Codonopsis 43 ~ 50g, Radix Gymnematis Sylvestris 40 ~ 47g, Radix Angelicae Sinensis 37 ~ 44g,

Radix Asparagi 34 ~ 41g, Radix Salviae Miltiorrhizae 31 ~ 38g, Herb Pararuelliae delavayanae 28 ~ 35g, Semen pini koraiensis 25 ~ 32g,

Radix achyranthis asperae (Herba Achyranthis Asperae) 22 ~ 29g, Flos Sophorae 19 ~ 26g, Fructus Ligustri Lucidi 16 ~ 23g, Fructus Lycii 13 ~ 20g,

Rod rod grass 10 ~ 17g, Adeps Elaphuri davidiani 8 ~ 14g, Cortex sophorae 5 ~ 12g, Fructus Atriplicis Sibiricae 2 ~ 7g.

The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.

Embodiment 3

The raw material composition of effective ingredient of the present invention and weight are:

Little leaf of Broussonetia papyrifera (L.) L.Her.ex Vent. 78g, Radix Hedysari 74g, Folium Sansevieriae Trifasclatae 71g, Radix Adenophorae (Radix Glehniae) 67g,

Radix ampelopsis brevipedunculatae 64g, Rhizoma Atractylodis Macrocephalae 60g, Radix Ophiopogonis 56g, Radix Glycyrrhizae 53g,

Fruitlet Mecodium badium (Hook. Et Grev.) Cop. 50g, Radix Codonopsis 47g, Radix Gymnematis Sylvestris 44g, Radix Angelicae Sinensis 41g,

Radix Asparagi 37g, Radix Salviae Miltiorrhizae 34g, Herb Pararuelliae delavayanae 31g, Semen pini koraiensis 28g,

Radix achyranthis asperae (Herba Achyranthis Asperae) 25g, Flos Sophorae 23g, Fructus Ligustri Lucidi 20g, Fructus Lycii 17g,

Excellent careless 14g, Adeps Elaphuri davidiani 11g, Cortex sophorae 8g, Fructus Atriplicis Sibiricae 4g.

The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.

Clinical data:

1, case selection

The routine clinical observation of radiodermatitis patient 60 selecting my institute to make a definite diagnosis, patient is divided into two groups at random.Treatment group 30 example, wherein male 19 example, women 11 example, 23 ~ 66 years old age, 41.6 years old mean age; Matched group 30 example, wherein male 20 example, women 10 example, 22 ~ 67 years old age, 41.9 years old mean age.Two groups of patient's qualifications and record of service are basically identical, without significant difference, have comparability.

2, treatment group patient takes medicine of the present invention, and each 1 bag of every day 3 times, half an hour ante cibum takes after mixing it with water with boiled water, within 10 days, is 1 course for the treatment of.Matched group patient, according to the clinical symptoms of the radiodermatitis diagnosed out, gives doctor trained in Western medicine symptomatic treatment.

3, efficacy determination:

(1) cure: clinical symptom disappearance, do not stay dysfunction.

(2) take a turn for the better: clinical symptoms takes a turn for the better, or clinical symptom disappearance but leave slight dysfunction.

(3) invalid: symptom is with treating front no significant difference.

4, result

Treatment group cure rate 66.7%, total effective rate 96.7%, matched group cure rate 43.3%, total effective rate 90%, two groups of comparitive study, difference has statistical significance (P<0.05), therefore treatment group is obviously better than matched group for the curative effect of primary disease.

Table 1 liang group patient clinical comparitive study

Model case is illustrated:

1, neat ××, female, 55 years old.This patient carries out radiotherapy because suffering from breast cancer, and radiotherapy 1 week rear axillary fossa place skin has the symptoms such as dry desquamation, erythema, redness to occur, and skin has the sensation of pruritus.Institute's inquiring afterwards, is diagnosed as radiodermatitis, and after taking 1 course for the treatment of of Chinese medicine of the present invention, above-mentioned symptom obviously alleviates, and follow the doctor's advice after continuing to take 1 course for the treatment of of Chinese medicine of the present invention, clinical symptoms disappears completely, fully recovers.

2, Cai's ××, man, 37 years old.Patient accepts radiotherapy because of nasopharyngeal carcinoma, and edematous erythema appears in rear irradiated region skin, has scorching hot, scratchiness.Institute's inquiring afterwards, is diagnosed as radiodermatitis, and after taking 1 course for the treatment of of Chinese medicine of the present invention, clinical symptoms disappears completely, fully recovers.

3, Zou's ××, man, 53 years old.Patient accepts radiotherapy because of neck malignant tumor, and red and swollen and vesicle appear in rear irradiated region internal collar skin, and have ulceration liquid to ooze out, and causalgia scratchiness is strong.Institute's inquiring afterwards, is diagnosed as radiodermatitis, and after taking 3 courses for the treatment of of Chinese medicine of the present invention, clinical symptoms disappears completely, fully recovers.

Even to this day, radiotherapy is still the important means for the treatment of malignant tumor, is widely used in the malignant tumor such as treatment nasopharyngeal carcinoma, breast carcinoma, the esophageal carcinoma.During radiotherapy, ray is while killing off tumor cells, also produces biological effect and destruction to normal cell, makes most of patient's local skin generation damage in various degree, causes radiodermatitis disease and produce.Chinese medicine of the present invention forms according to long-term clinical practice configuration, and in side, selected herbal nature is suitable mutually auxiliary mutually, suits the remedy to the case according to the cause of disease, and Fructus Ligustri Lucidi in side, Fructus Lycii can nourishing the liver and kidney; Radix Codonopsis in side, the Rhizoma Atractylodis Macrocephalae can invigorating the spleen and benefiting QI; In side, Radix Angelicae Sinensis can be enriched blood and be invigorated blood circulation; Radix Ophiopogonis in side, Radix Adenophorae (Radix Glehniae), rod rod grass, Radix Asparagi can lung moistening clear away heart-fire, YIN nourishing and the production of body fluid promoting; Radix Salviae Miltiorrhizae in side, Radix achyranthis asperae (Herba Achyranthis Asperae) can blood circulation promoting and blood stasis dispelling, removing heat from blood eliminating carbuncle; In side Flos Sophorae can purging liver-fire, cooling blood for hemostasis; Fang Zhong little leaf of Broussonetia papyrifera (L.) L.Her.ex Vent., Radix Hedysari, Folium Sansevieriae Trifasclatae, Radix ampelopsis brevipedunculatae, fruitlet Mecodium badium (Hook. Et Grev.) Cop., Radix Gymnematis Sylvestris, Herb Pararuelliae delavayanae, Cortex sophorae, Fructus Atriplicis Sibiricae can heat-clearing and toxic substances removing, dispelling wind for relieving itching, reducing swelling and alleviating pain, sore hemostasis, removing the necrotic tissue and promoting granulation; Semen pini koraiensis in side, Adeps Elaphuri davidiani can nourishing blood to expel wind, moist skin; In side, Radix Glycyrrhizae can coordinating the actions of various ingredients in a prescription; In side, all medicines share, effect of liver and kidney tonifying, vigorate qi and replenish the blood, blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing, YIN nourishing and the production of body fluid promoting, repellent antipruritic, expelling pus and promoting granulation, moist skin can be played altogether, good absorbing effect, evident in efficacy, the healing of wound surface can be accelerated, alleviate patient suffering, alleviate radiotherapy side reaction, ensure radiocurablely to carry out smoothly, have no side effect and clinical adverse, higher to radiodermatitis cure rate through clinical verification.

Claims (4)

1. be used for the treatment of an instant particles as Chinese medicine for radiodermatitis, it is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:

Little leaf of Broussonetia papyrifera (L.) L.Her.ex Vent. 70 ~ 85 parts, Radix Hedysari 66 ~ 82 parts, Folium Sansevieriae Trifasclatae 63 ~ 78 parts, Radix Adenophorae (Radix Glehniae) 60 ~ 74 parts,

Radix ampelopsis brevipedunculatae 56 ~ 70 parts, the Rhizoma Atractylodis Macrocephalae 53 ~ 67 parts, Radix Ophiopogonis 50 ~ 63 parts, 46 ~ 60 parts, Radix Glycyrrhizae,

Fruitlet Mecodium badium (Hook. Et Grev.) Cop. 43 ~ 56 parts, Radix Codonopsis 40 ~ 53 parts, Radix Gymnematis Sylvestris 37 ~ 50 parts, Radix Angelicae Sinensis 34 ~ 47 parts,

Radix Asparagi 31 ~ 44 parts, Radix Salviae Miltiorrhizae 28 ~ 41 parts, Herb Pararuelliae delavayanae 25 ~ 38 parts, Semen pini koraiensis 22 ~ 35 parts,

Radix achyranthis asperae (Herba Achyranthis Asperae) 19 ~ 32 parts, 16 ~ 29 parts, Flos Sophorae, Fructus Ligustri Lucidi 13 ~ 26 parts, Fructus Lycii 10 ~ 23 parts,

Rod rod grass 7 ~ 20 parts, Adeps Elaphuri davidiani 5 ~ 17 parts, Cortex sophorae 3 ~ 14 parts, Fructus Atriplicis Sibiricae 1 ~ 10 part.

2. a kind of instant particles as Chinese medicine being used for the treatment of radiodermatitis according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:

Little leaf of Broussonetia papyrifera (L.) L.Her.ex Vent. 74 ~ 82 parts, Radix Hedysari 70 ~ 78 parts, Folium Sansevieriae Trifasclatae 66 ~ 75 parts, Radix Adenophorae (Radix Glehniae) 63 ~ 70 parts,

Radix ampelopsis brevipedunculatae 60 ~ 67 parts, the Rhizoma Atractylodis Macrocephalae 56 ~ 64 parts, Radix Ophiopogonis 53 ~ 60 parts, 50 ~ 56 parts, Radix Glycyrrhizae,

Fruitlet Mecodium badium (Hook. Et Grev.) Cop. 46 ~ 53 parts, Radix Codonopsis 43 ~ 50 parts, Radix Gymnematis Sylvestris 40 ~ 47 parts, Radix Angelicae Sinensis 37 ~ 44 parts,

Radix Asparagi 34 ~ 41 parts, Radix Salviae Miltiorrhizae 31 ~ 38 parts, Herb Pararuelliae delavayanae 28 ~ 35 parts, Semen pini koraiensis 25 ~ 32 parts,

Radix achyranthis asperae (Herba Achyranthis Asperae) 22 ~ 29 parts, 19 ~ 26 parts, Flos Sophorae, Fructus Ligustri Lucidi 16 ~ 23 parts, Fructus Lycii 13 ~ 20 parts,

Rod rod grass 10 ~ 17 parts, Adeps Elaphuri davidiani 8 ~ 14 parts, Cortex sophorae 5 ~ 12 parts, Fructus Atriplicis Sibiricae 2 ~ 7 parts.

3. a kind of instant particles as Chinese medicine being used for the treatment of radiodermatitis according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:

Little leaf of Broussonetia papyrifera (L.) L.Her.ex Vent. 78 parts, Radix Hedysari 74 parts, Folium Sansevieriae Trifasclatae 71 parts, Radix Adenophorae (Radix Glehniae) 67 parts,

Radix ampelopsis brevipedunculatae 64 parts, the Rhizoma Atractylodis Macrocephalae 60 parts, Radix Ophiopogonis 56 parts, 53 parts, Radix Glycyrrhizae,

Fruitlet Mecodium badium (Hook. Et Grev.) Cop. 50 parts, Radix Codonopsis 47 parts, Radix Gymnematis Sylvestris 44 parts, Radix Angelicae Sinensis 41 parts,

Radix Asparagi 37 parts, Radix Salviae Miltiorrhizae 34 parts, Herb Pararuelliae delavayanae 31 parts, Semen pini koraiensis 28 parts,

Radix achyranthis asperae (Herba Achyranthis Asperae) 25 parts, 23 parts, Flos Sophorae, Fructus Ligustri Lucidi 20 parts, Fructus Lycii 17 parts,

Rod rod grass 14 parts, Adeps Elaphuri davidiani 11 parts, Cortex sophorae 8 parts, Fructus Atriplicis Sibiricae 4 parts.

4. a kind of preparation method being used for the treatment of the instant particles as Chinese medicine of radiodermatitis according to claims 1 to 3, is characterized in that: comprise following processing step:

(1) little leaf of Broussonetia papyrifera (L.) L.Her.ex Vent., Folium Sansevieriae Trifasclatae, Radix Adenophorae (Radix Glehniae), Radix ampelopsis brevipedunculatae, the Rhizoma Atractylodis Macrocephalae, Radix Ophiopogonis, fruitlet Mecodium badium (Hook. Et Grev.) Cop., Radix Gymnematis Sylvestris, Radix Asparagi, Herb Pararuelliae delavayanae, Semen pini koraiensis, Radix achyranthis asperae (Herba Achyranthis Asperae), Fructus Ligustri Lucidi, rod rod grass, Cortex sophorae, Fructus Atriplicis Sibiricae are cleaned, dried rear mix homogeneously, put into container, add the water of 6 ~ 8 times amount in a reservoir, heated and boiled 2 ~ 3 hours, gets immersion after cooling; In remaining medicinal residues, add the water of 4 ~ 6 times amount again, heated and boiled 1 ~ 2 hour, gets immersion after cooling; Merge twice gained immersion, heating, evaporation and concentration is the thick paste of relative density 1.15 ~ 1.25, for subsequent use;

(2) Radix Angelicae Sinensis, Fructus Lycii are put into container, add the shao-hsing rice wine of 3 ~ 5 times amount, cool after boiling, continue immersion 3 ~ 5 hours, get immersion; In remaining medicinal residues, add the shao-hsing rice wine of 2 ~ 4 times amount again, put after boiling and dry in the air, continue immersion 2 ~ 4 hours, get immersion; Merge twice gained immersion, add and steam the thick paste that evaporation and concentration is relative density 1.10 ~ 1.20, for subsequent use;

(3) clean Radix Hedysari sheet is added cooked Mel and a little boiled water, mixes thoroughly slightly vexed, put in pot fry to yellow and tack-free time, take out and dry in the air cool, pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;

(4) get clean Radix Glycyrrhizae tabellae, add cooked Mel and a little boiled water, slightly vexed after mixing thoroughly, put in parch container, slow fire is fried to buff, and take out time tack-free, cool, pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;

(5) be placed in the pot of heating by wheat bran, when playing cigarette to pot, add Radix Codonopsis sheet, stir to buff, take out sieve and remove wheat bran, cool, pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;

(6) get Radix Salviae Miltiorrhizae Tabellae, add yellow wine and mix thoroughly, moistening is to saturating, and put in pot, use slow fire fried dry, taking-up cools, and pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;

(7) get clean Flos Sophorae, fry to surperficial buff by frying method, taking-up cools, and pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;

(8) Adeps Elaphuri davidiani is added a small amount of boiled water to mix thoroughly, then water proof is heated to Adeps Elaphuri davidiani and dissolves completely, obtains medicinal liquid, for subsequent use.

(9) by the thick paste of step (1), step (2) gained, mix with the fine powder of gained in step (3), step (4), step (5), step (6), step (7) and the medicinal liquid of the middle gained of step (8), add adjuvant sucrose and dextrin mix homogeneously makes granule, after drying, granulate, be packaged into the instant particles as Chinese medicine of every bag of 10g.