CN105663365A

CN105663365A - Traditional Chinese medicine granules for relieving itching and pain after operation with anesthesia and preparation method

Info

Publication number: CN105663365A
Application number: CN201610202446.1A
Authority: CN
Inventors: 韩永吉
Original assignee: Qingdao Zhixintiancheng Technology Development Co Ltd
Current assignee: Qingdao Zhixintiancheng Technology Development Co Ltd
Priority date: 2016-04-01
Filing date: 2016-04-01
Publication date: 2016-06-15

Abstract

The invention discloses traditional Chinese medicine granules for relieving itching and pain after an operation with anesthesia and a preparation method, belonging to the field of traditional Chinese medicines. The traditional Chinese medicine granules are prepared from the following raw materials as medical effective ingredients: dandelion, astragalus root, angelica, oldenlandia, black sesame seed, dangshen, pine needle, mulberries, Chinese starjasmine stem, white atractylodes rhizome, licorice, Korean pine seed, tuber fleeceflower stem, red sage root, blumea megacephala, cortex dictamni radicis, broom cypress fruit, corydalis tuber, futokadsura stem, Sichuan cinnamon, lycopodium clavatum, cicada shell, hairyleaf litse fruit and bitter citrus immature flower. The selected medicinal materials conform to the assistant and guide principle; the traditional Chinese medicine granules can act appropriately according to the pathogenesis, have the effects of replenishing qi and enriching blood, enriching blood and moistening dryness, promoting flow of qi and blood circulation, promoting blood circulation and removing blood stasis, clearing away heat and promoting diuresis, dispelling wind and arresting itching, detoxifying and eliminating swelling, activating meridians to stop pain as well as harmonizing the stomach and alleviating vomiting, and are good in absorption effect, obvious in curative effect, free of toxic or side effect and free of clinical adverse reaction; and through clinical verification, the traditional Chinese medicine granules have a relatively high cure rate for itching and pain after the operation with anesthesia.

Description

A kind of instant particles as Chinese medicine for anaesthetizing postoperative pruritus pain relief and preparation method

Art

The present invention relates to the field of Chinese medicines, particularly relate to a kind of instant particles as Chinese medicine for anaesthetizing postoperative pruritus pain relief and preparation method.

Background technology

Anesthesia represents " consciousness, sensory deprivation ". Sensory deprivation can be locality, is namely embodied in certain position of health, it is also possible to be general, is namely presented as systemic unconsciousness, it is not intended to know. From medical angle, anesthesia is meant that and makes patient overall by medicine or additive method or be locally temporarily lost with sensation, to reach painless purpose, treats offer condition for operative treatment or other medical examination. And the symptom carrying out the operation application the most common post-operative complication of anesthetics has pruritus, pain and nausea and vomiting etc., though the life of patient will not be constituted danger by these untoward reaction, but leverage the recovery after operation in patients.

Cause the mechanism anaesthetizing postoperative pruritus very complicated, not yet illustrate completely at present. Anaesthetize postoperative pruritus position not fix, doctor trained in Western medicine external used medicine is used to smear inconvenience, generally suit the medicine to the illness and use Loratadine to carry out antipruritic, acute pruritus is affected sleeper and can use calm, somnifacient, and analgesic type drug is generally used for postoperative pain and eases pain. Although using these medicine quick results, but there is certain side effect, and the treatment group later stage is long, brings misery and inconvenience to patient.

It is considered herein that consumption impairment of QI blood during patient's anesthesia surgery, so that patients blood is not enough, Shi Re Bing Pian accumulates in skin, blocks meridians, and blood does not support skin, blood-deficiency and wind-dry, dedicates one's life to humorously and itches, and qi depression to blood stasis, stagnation of QI and blood may bring about pain. The present invention suits the remedy to the case according to the cause of disease, there is effect of vigorate qi and replenish the blood, blood enriching and dryness moistening, promoting flow of QI and blood, blood circulation promoting and blood stasis dispelling, clearing away heat-damp and promoting diuresis, dispelling wind for relieving itching, removing toxic substances and promoting subsidence of swelling, removing obstruction in the collateral to relieve pain, stomach function regulating preventing or arresting vomiting, can benefiting vital QI and blood, make venation unimpeded, QI and blood is smooth, improve microcirculation around, reduce inflammation reaction, promote wound healing, eliminate scalpel edge and swell and ache, relieving itch, good absorbing effect, evident in efficacy, have no side effect and clinical adverse, higher to anaesthetizing postoperative pruritus pain cure rate according to clinical verification.

Summary of the invention

The invention provides a kind of instant particles as Chinese medicine for anaesthetizing postoperative pruritus pain relief and preparation method, there is effect of vigorate qi and replenish the blood, blood enriching and dryness moistening, promoting flow of QI and blood, blood circulation promoting and blood stasis dispelling, clearing away heat-damp and promoting diuresis, dispelling wind for relieving itching, removing toxic substances and promoting subsidence of swelling, removing obstruction in the collateral to relieve pain, stomach function regulating preventing or arresting vomiting, cure the disease and seek source treating both the principal and secondary aspects of a disease, be respectively provided with good curative effect for anaesthetizing the ill symptomses such as postoperative pruritus pain.

For achieving the above object, technical scheme is implemented as follows:

A kind of instant particles as Chinese medicine for anaesthetizing postoperative pruritus pain relief, make described effective ingredient raw material composition and parts by weight be:

Herba Taraxaci 70～88 parts, the Radix Astragali 67～85 parts, Radix Angelicae Sinensis 64～82 parts, Herba Hedyotidis Diffusae 60～78 parts,

Semen Sesami Nigrum 57～75 parts, Radix Codonopsis 53～72 parts, 50～68 parts of Folium Pini, Fructus Mori 47～65 parts,

Caulis Trachelospermi 44～62 parts, the Rhizoma Atractylodis Macrocephalae 41～59 parts, 38～56 parts of Radix Glycyrrhizae, Semen pini koraiensis 35～52 parts,

Caulis Polygoni Multiflori 32～48 parts, Radix Salviae Miltiorrhizae 29～44 parts, Herba Blumeae clarkei 26～40 parts, Cortex Dictamni 23～37 parts,

The Fructus Kochiae 20～34 parts, Rhizoma Corydalis 17～30 parts, Caulis Piperis Kadsurae 14～27 parts, 12～24 parts of river Cortex cinnamomi japonici (Ramulus Cinnamomi),

Herba Lycopodii 10～20 parts, Periostracum Cicadae 8～17 parts, clear Fructus Solani melongenae 5～14 parts, Citrus aurantium L. var. amara Engl. 2～10 parts.

Make described effective ingredient raw material composition and parts by weight be:

Herba Taraxaci 73～85 parts, the Radix Astragali 70～82 parts, Radix Angelicae Sinensis 67～78 parts, Herba Hedyotidis Diffusae 63～75 parts,

Semen Sesami Nigrum 60～72 parts, Radix Codonopsis 56～68 parts, 53～65 parts of Folium Pini, Fructus Mori 50～62 parts,

Caulis Trachelospermi 47～58 parts, the Rhizoma Atractylodis Macrocephalae 44～56 parts, 41～53 parts of Radix Glycyrrhizae, Semen pini koraiensis 38～48 parts,

Caulis Polygoni Multiflori 35～45 parts, Radix Salviae Miltiorrhizae 32～40 parts, Herba Blumeae clarkei 29～37 parts, Cortex Dictamni 26～34 parts,

The Fructus Kochiae 23～31 parts, Rhizoma Corydalis 20～27 parts, Caulis Piperis Kadsurae 17～24 parts, 15～21 parts of river Cortex cinnamomi japonici (Ramulus Cinnamomi),

Herba Lycopodii 13～17 parts, Periostracum Cicadae 10～15 parts, clear Fructus Solani melongenae 7～11 parts, Citrus aurantium L. var. amara Engl. 4～7 parts.

Herba Taraxaci 79 parts, the Radix Astragali 76 parts, Radix Angelicae Sinensis 73 parts, Herba Hedyotidis Diffusae 70 parts,

Semen Sesami Nigrum 66 parts, Radix Codonopsis 63 parts, 59 parts of Folium Pini, Fructus Mori 56 parts,

Caulis Trachelospermi 53 parts, the Rhizoma Atractylodis Macrocephalae 50 parts, 47 parts of Radix Glycyrrhizae, Semen pini koraiensis 43 parts,

Caulis Polygoni Multiflori 40 parts, Radix Salviae Miltiorrhizae 36 parts, Herba Blumeae clarkei 33 parts, Cortex Dictamni 30 parts,

The Fructus Kochiae 27 parts, Rhizoma Corydalis 24 parts, Caulis Piperis Kadsurae 21 parts, 18 parts of river Cortex cinnamomi japonici (Ramulus Cinnamomi),

Herba Lycopodii 15 parts, Periostracum Cicadae 12 parts, clear Fructus Solani melongenae 9 parts, Citrus aurantium L. var. amara Engl. 5 parts.

The preparation method of a kind of instant particles as Chinese medicine for anaesthetizing postoperative pruritus pain relief, comprises the following steps that:

(1) Herba Taraxaci, Herba Hedyotidis Diffusae, Semen Sesami Nigrum, Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae, Semen pini koraiensis, Caulis Polygoni Multiflori, Herba Blumeae clarkei, Cortex Dictamni, the Fructus Kochiae, river Cortex cinnamomi japonici (Ramulus Cinnamomi), Periostracum Cicadae, clear Fructus Solani melongenae, Citrus aurantium L. var. amara Engl. are cleaned, dried rear mix homogeneously, put in container, add the water of 6～8 times amount in a reservoir, heated and boiled 2～3 hours, takes immersion after cooling; Remaining medicinal residues add the water of 4～6 times amount, heated and boiled 1～2 hour, after cooling, takes immersion; Merge twice gained immersion, heating, evaporation and concentration is the thick paste of relative density 1.15～1.25, standby;

(2) Radix Angelicae Sinensis, Folium Pini, Fructus Mori, Caulis Trachelospermi, Caulis Piperis Kadsurae, Herba Lycopodii are put in container, add the shao-hsing rice wine of 3～5 times amount, cool after boiling, continue immersion 3～5 hours, take immersion; Remaining medicinal residues add the shao-hsing rice wine of 2～4 times amount, puts after boiling and dry in the air, continue immersion 2～4 hours, take immersion; Merge twice gained immersion, add and steam the thick paste that evaporation and concentration is relative density 1.10～1.20, standby;

(3) astragalus mongholicus tablet is added cooked Mel and a little boiled water, mixes thoroughly slightly vexed, put fry in pot to yellow and tack-free time, taking-up cools, and pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, standby;

(4) taking Radix Salviae Miltiorrhizae Tabellae, add yellow wine and mix thoroughly, moistening, to thoroughly, is put in pot, fries with slow fire, and taking-up cools, and pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, standby;

(5) take clean Rhizoma Corydalis, mix thoroughly with vinegar, infiltration, exhaust to vinegar, put in pot and fry to micro-dry with slow fire, take out, cool, sieve removes chip, and pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, standby;

(6) by the thick paste of step (1), step (2) gained, mix with the fine powder of gained in step (3), step (4), step (5), add adjuvant sucrose and dextrin mix homogeneously makes granule, after dry, granulate, it is packaged into the instant particles as Chinese medicine of every bag of 10g.

The property of medicine of Chinese medicine used by the present invention is as follows:

Herba Taraxaci: bitter in the mouth; Sweet; Cold in nature. Return liver; Stomach warp. Heat-clearing and toxic substances removing; Eliminating carbuncle eliminating stagnation. Cure mainly acute mastitis; Lung abscess; Intestinal carbuncle; Mumps; Furuncle carbuncle toxin; Conjunctival congestion and swelling pain; Cold, fever; Cough; Laryngopharynx swelling and pain; Stomach-fire; Intestinal is scorching; Dysentery; Hepatitis; Cholecystitis; Urinary tract infection; Snake bite and insect sting. " the southern regions of the Yunnan Province book on Chinese herbal medicine " load: " control all pyogenic infections from tumour or sore, ruined tinea skin ulcer; Dispeling the wind, disappear all sores, dissipates scrofula tuberculosis; Stop little having blood in stool, control the five types of stranguria difficulty in urination, profit bladder. " clinic study shows, dandelion preparation can replace antibiotics to use to a certain extent, some disease shows effect of broad-spectrum antibiotic, has certain antiviral functions.

The Radix Astragali: sweet in the mouth; Warm in nature. Enter the heart; Lung; Spleen; Kidney channel. Invigorating QI to consolidate the body surface resistance; Diuresis; Expelling pus and toxin by strengthening QI; Promoting tissue regeneration and ulcer healing. Cure mainly cardiopalmus of breathing hard; Asthenia; Weak; Spontaneous perspiration; Night sweat; Chronic diarrhea; Proctoptosis; Body is impractical swollen; Uterine prolapse; Chronic nephritis; Carbuncle difficulty is burst; Or burst do not hold back for a long time. " Xinhua's book on Chinese herbal medicine outline " carries: " have the function of invigorating QI to consolidate the body surface resistance, expelling pus and toxin by strengthening QI, granulation promoting. " modern medicine study confirms; the Radix Astragali is mainly composed of Radix Astragali total flavones, Radix Astragali Mongolici total polysaccharide, Radix Astragali total saponins and aminoacid etc.; have diuretic antihypertensive, anti-inflammatory analgesic, heart tonifying, antioxidant radical generate and improve the multiple pharmacological effect such as body's immunity; can act on body from many aspects, improves the relevant blood vessel sexually transmitted disease (STD)s such as cardiovascular, cerebrovascular, diabetes, nephropathy and becomes the function such as hemodynamics and vascular endothelial cell of patient.

Radix Angelicae Sinensis: sweet in the mouth; Pungent; Warm in nature. Return liver, the heart, spleen channel. Replenishing and activating blood; Menstruction regulating and pain relieving; Loosening bowel to relieve constipation. Cure mainly blood deficiency and yellow complexion; Dizziness cardiopalmus; Asthenia cold abdominalgia; Rheumatic arthralgia; Injury from falling down; Ulcer sores. " book on Chinese herbal medicine is just " carries: " its sweet in the mouth and weigh, therefore specially can enrich blood, its gas is light and pungent, therefore again can promoting the circulation of blood, can support nutrition blood, QI invigorating spermatogenesis, settling five organs, strong body, beneficial mind, all tangible deficient diseases, nothing unsuitable. " modern medicine study confirmation, Radix Angelicae Sinensis has antibacterial, antiinflammation, and chronic articular rheumatism acute attack is had obvious inhibitory action.

Herba Hedyotidis Diffusae: bitter in the mouth; Sweet; Cold in nature; Nontoxic. Enter the heart; Liver; Spleen; Large intestine channel. Heat-clearing and toxic substances removing; Dampness removing. Cure mainly dyspnea and cough due to lung-heat; Laryngopharynx swelling and pain; Intestinal carbuncle; Furuncle and phyma skin infection; Venom; The puckery pain of pyretic stranguria; Edema; Dysentery; Intestinal is scorching; Jaundice due to damp-heat; Cancerous protuberance. " Quanzhou book on Chinese herbal medicine " load: " heat clearing away dissipating blood stasis, eliminating carbuncle detoxifies. Control ulcer sores, scrofula. Again can lung heat clearing fire, eliminating the pathogens from the lung heat. Control lung-heat dyspnea with rapid and short breath, cough against uncomfortable in chest. " modern medicine study confirmation; the tumor cell of acute lymphoblastic type, granulocyte type, monocyte type and chronic granulocyte type is all had stronger inhibitory action by Herba Hedyotidis Diffusae; stimulate reticuloendothelial system hypertrophy; strengthen phagocyte vigor, staphylococcus aureus, state's Shigella flexneri, Bacillus typhi, bacillus pyocyaneus are all had inhibitory action.

Semen Sesami Nigrum: sweet in the mouth; Property is put down. Return liver; Spleen; Kidney channel. Liver and kidney tonifying; The benefit that nourishes blood essence; Loosening bowel to relieve constipation. For dizziness and blurred vision, Hiccough and deaf, early whitening of beard and hair, post disease alopecia, dryness of the intestine constipation. Modern medicine study proves: Semen Sesami Nigrum has hypoglycemic activity, short adrenal gland's effect, antiinflammatory action and cardiovascular is had certain effect.

Radix Codonopsis: sweet in the mouth; Property is put down. Return spleen; Lung meridian. Strengthening the spleen and tonifying the lung; Supplementing QI for promoting the production of body fluid. Cure mainly weakness of the spleen and stomach; Anorexia and loose stool; Limbs fatigue; The deficiency of the lung is breathed with cough; Breathe hard spontaneous perspiration; The all cards of deficiency of both QI and blood. " moral joins book on Chinese herbal medicine " carries: " lung heat clearing gold, invigorating primordial QI, open sound, help biceps. " modern medicine study confirms; Radix Codonopsis energy Gastrointestinal motility adjustment, antiulcer, enhancing immunologic function; on excited and suppress two kinds of nervous process to have impact, erythrocyte, hemoglobin, reticulocyte can be raised, also have the effect of slow down aging and antioxidation, radioprotective, blood pressure lowering.

Folium Pini: bitter in the mouth; Warm in nature. GUIXIN; Spleen channel. Dispeiling pathogenic wind and removing dampness; Killing parasites for relieving itching; Blood-promoting and mind-easing. Cure mainly rheumatism flaccidity syndrome and arthralgia syndrome; Foot gas; Eczema; Tinea; Rubella pruritus; Traumatic injury; Neurasthenia; Chronic nephritis; Hypertension. Preventing encephalitis, influenza. " conventional Chinese herbal medicine handbook ": controlling neurasthenia, Vitamin C lacks, trophedema; Prevent and treat epidemic encephalitis, influenza. Modern medicine study confirms: Folium Pini has the effect of calmness, cooling, analgesia, antiinflammatory, blood fat reducing, antiviral and slow down aging.

Fructus Mori: sweet in the mouth; Acid; Cold in nature. Return liver; Kidney channel. Nourishing YIN and benefiting blood; Promote the production of body fluid; Intestine moistening. Cure mainly having a dizzy spell of deficiency of the liver and kindey and blood deficiency damage of essence; Soreness of waist tinnitus; Early whitening of beard and hair; Insomnia and dreamful sleep; Tianjin wound is thirsty; Quench one's thirst; Dryness of the intestine constipation.

Caulis Trachelospermi: bitter in the mouth; Pungent; Cold nature. Enter the heart; Liver; Kidney channel. Removing obstruction in the collateral to relieve pain; Heat clearing and blood cooling; Removing toxic substances and promoting subsidence of swelling. Cure mainly rheumatic arthralgia; Soreness of waist and knee joint; Muscle arteries and veins contracture; Laryngopharynx swelling and pain; Furuncle swelling toxin; Traumatic injury; Traumatic hemorrhage. " book on Chinese herbal medicine justice " load: " this thing is apt to walk passages through which vital energy circulates, sensible podomere, the dead flesh of main air heat, supports kidney, main waist hip pain, hard muscle, profit joint. " modern medicine study confirms, staphylococcus aureus, shigella flexneri and Bacillus typhi are had stronger resistancing action, contained arctigenin can stimulate central nervous system by Caulis Trachelospermi, accelerate respiratory frequency, it is suppressed that blood vessel edema.

The Rhizoma Atractylodis Macrocephalae: bitter in the mouth; Sweet; Warm in nature. Return spleen; Stomach warp. Invigorating the spleen and benefiting QI; Dampness diuretic; Hidroschesis; Antiabortive. Cure mainly deficiency-weakness of spleen-QI; Spiritlessness and weakness; Lack of appetite abdominal distention; Big loose stool is thin; Fluid-retention stagnating in the interior; Dysuria; Edema; Dizziness due to fluid-retention; Arthralgia chiefly caused by damp pathogen is ached; Spontaneous sweating due to deficiency of QI; Frequent fetal movement. " herbal classic is met former " carries: " art, raw with there being dehumidifying benefit dry, expectorant diuretic, control anemofrigid-damp arthralgia, dead flesh convulsion subcutaneous ulcer, dissipate blood between waist umbilicus, and chong channel is disease, the merit of inverse gas pain in the abdomen; Make ripe, have and middle QI invigorating, slake thirst and help produce saliva, hidroschesis heat extraction, enters diet, antiabortive effect. " modern medicine study confirms, the Rhizoma Atractylodis Macrocephalae have diuresis, blood sugar lowering, strong, anticoagulation, antitumor, antibacterial, promote the effect of hemopoietic and protein synthesis.

Radix Glycyrrhizae: sweet in the mouth; Property is put down. GUIXIN; Lung; Spleen; Stomach warp. Invigorating the spleen and replenishing QI; Heat-clearing and toxic substances removing; Expelling phlegm for arresting cough; Relieving spasm to stop pain; Coordinating the actions of various ingredients in a prescription. Cure mainly weakness of the spleen and stomach; Fatigue and weakness; Shortness of breath and palpitation; Cough with copious phlegm; Gastral cavity abdomen four muscle spasm of the leg and foot pain; Carbuncle sore tumefacting virus; Cushion toxicity. Compendium of Material Medica is carried: " in all medicines, Radix Glycyrrhizae is monarch. Controlling 72 kinds of mammary calculus poison, draft is malicious by every means to solve 1,002, is in harmonious proportion and gains merit from medicine. " modern medicine study confirmation; Radix Glycyrrhizae has stronger Detoxication; also have antiulcer, anti-inflammatory, spasmolytic antitussive, blood pressure lowering, blood fat reducing, antitumaous effect; is widely used in the diseases such as treatment pharyngolaryngitis, laryngitis, tracheitis, bronchitis, asthma, cough, hemoptysis, additionally has anti-gastric-ulcer, gastritis effect.

Semen pini koraiensis: sweet in the mouth; Slightly warm in nature. Return liver; Lung; Large intestine channel. Moisturize, nourish blood, dispel the wind. Cure mainly dryness of the lung dry cough, constipation due to insufficiency of defecating, all dizziness due to wind, joint wind, migratory arthralgia. And have moist skin, apply the function of Rong Maofa. " Japan hanako materia medica ": by migratory arthralgia cold, the few gas of weakness with emaciation, tonifying for the deficiency, moistens skin, fertile the five internal organs.

Caulis Polygoni Multiflori: sweet in the mouth; Micro-hardship; Property is put down. Enter the heart; Liver Channel. Tranquilizing by nourishing the heart; Dispel the wind; Dredging collateral. Cure mainly insomnia; Dreaminess; Blood deficiency general pain; Numbness of the skin; Rheumatic arthralgia; Rubella pruritus. " decoction pieces is newly joined " carries: " nourishing the liver and kidney, only sweating due to debility, hypnosis of calming the nerves, invigorating middle warmer gas, network of passing through, promoting blood circulation, control impairment caused by overstrain. " modern medicine study confirmation, Caulis Polygoni Multiflori contains rheum emodin, physcione, is synergism with pentobarbital sodium, has significant calmness, syngignoscism, especially extends S sleep phase.

Radix Salviae Miltiorrhizae: bitter in the mouth; Cold nature; Nontoxic. Enter the heart; Liver Channel. Blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, clear away heart-fire relieving restlessness, removing heat from blood eliminating carbuncle. For obstruction of qi in the chest and cardialgia, gastral cavity abdomen hypochondriac pain, abdominal mass abdominal mass is gathered, pyretic arthralgia pain, dysphoria and insomnia, menoxenia, and dysmenorrhea amenorrhea, skin infection swells and ache. " herbal classic " carries: " main trusted subordinate's pathogen, borborygmus are faint as leaked water, and cold and heat gather; Broken disease, except abdominal mass, stops stuffy sensation with restlessness, QI invigorating. " modern medicine study confirms; Radix Salviae Miltiorrhizae has anti-inflammatory analgetic, coronary artery dilator, improves myocardial ischemia situation, blood pressure lowering, blood sugar lowering, blood fat reducing, protect the liver, antibacterial and promote repairing and the effect of regeneration of tissue, Radix Salviae Miltiorrhizae also has anti-platelet aggregation, reduces blood viscosity and regulate the function of inside and outside blood coagulation system.

Herba Blumeae clarkei: bitter in the mouth; Micro-pungent; Cool in nature. Clearing away heat to improve acuity of vision; Dispelling wind for relieving itching; Removing toxic substances and promoting subsidence of swelling. Cure mainly conjunctival congestion and swelling pain; Pterygium; Rubella; Scabies; Skin pruritus; Carbuncle furuncle; Traumatic injury is red and swollen.

Cortex Dictamni: bitter in the mouth; Salty; Cold in nature. Enter spleen; Lung; Small intestinal; Stomach; Bladder warp. Heat clearing and damp drying; Dispelling wind for relieving itching; Removing toxic substances. Cure mainly the rubella caused by wind heat noxious dampness; Eczema; Scabies; Jaundice; Damp-heat arthralgia. " property of medicine opinion " carries: " controlling all pyretic toxicity wind, aversion to wind, wind skin ulcer, scabies are red rotten, and eyebrow loss of hairs is crisp, and musculus cutaneus is anxious, high fever aversion to cold; Principal solution heat Huang, wine Huang, acute jaundice, yellow, the labor Huang of paddy etc. " modern medicine study shows, multiple pathomycete is all had inhibitory action in various degree by Cortex Dictamni, can excited heart, increase cardiac muscular tension, in addition with effects such as anticancer, spasmolytic significantly, removing toxic substances.

The Fructus Kochiae: bitter in the mouth; Cold in nature. Return kidney; Bladder warp. Clearing away heat-damp and promoting diuresis; Dispelling wind for relieving itching. Cure mainly dysuria; Stranguria with turbid discharge; Leukorrhagia; Dysentery; Rubella; Eczema; Scabies; Skin pruritus; Sore. " not Lu ": steam in peeling skin, dissipates malignant boil, hernia abdominal mass, reinforcing YIN-essence, makes people moisten. Modern medicine study proves: Fructus Kochiae water logging agent has effect that is antibacterial and that suppress allergy.

Rhizoma Corydalis: acrid in the mouth; Bitter; Warm in nature; Nontoxic. Return liver; Stomach; The heart; Lung; Spleen channel. Invigorate blood circulation; Dissipating blood stasis; Regulate the flow of vital energy; Pain relieving. Cure mainly trusted subordinate's all pains of waist knee joint; Menoxenia; Lump in the abdomen; Metrorrhagia; Puerperal blood faints; Lochiorrhea; Traumatic injury. " detailed outline " carries: " stagnation of QI, stasis in gas in energy promoting the circulation of blood, therefore specially control upper and lower all pains all over the body, among using, simply fantastic. Invigorate blood circulation, promoting the circulation of QI, pain relieving, diuresis. " modern medicine study shows, Rhizoma Corydalis has significant analgesia, calmness, hypnosis, stable effect, excited gastrointestinal smooth muscle, significantly expands coronary vasodilator, can cause the secretion of PATH, muscle is had relaxation effect.

Caulis Piperis Kadsurae: acrid in the mouth; Bitter; Slightly warm in nature. Wind-damp dispelling; The meridian dredging; Regulate the flow of vital energy; Pain relieving. Cure mainly anemofrigid-damp arthralgia; Arthrodynia of extremities; Muscle arteries and veins contracture; Coldness and pain in the epigastrium; Edema. " Kaibao Bencao " carries: " main air blood, mends aging, plays sun, strong waist foot, eliminating impediment, bleaches, and by cold air, air draft is evil. Also liquor clothes, also infusing drugs in wine clothes, the eleventh month of the lunar calendar uses it. " modern medicine study confirmation, Caulis Piperis Kadsurae can increase myocardial alimentary blood flow, reduces myocardial ischemia district collateral blood vessels resistance, alleviates endotoxemia and Pulmonary vascular cell permeability increases the pulmonary edema caused.

River Cortex cinnamomi japonici (Ramulus Cinnamomi): acrid in the mouth; Sweet; Warm in nature. Dispelling cold by warming the meridian; Promoting flow of QI and blood; Pain relieving. Cure mainly: anemofrigid cold; Stomachache with cool feeling; Dysmenorrhea; Fengshi Guanjie pain; Traumatic injury; Fracture.

Herba Lycopodii: bitter in the mouth; Pungent; Warm in nature. Enter Liver Channel. Expelling wind and removing dampness; Dredge the meridian passage; Reducing swelling and alleviating pain. Cure mainly lumbago, skelalgia of rheumatism; Arthralgia; Traumatic injury; Knife injury; Burn and scald. " Hunan medicine will " carries: " relaxing muscles and tendons to promote blood circulation, invigorating qi and dredging collateral. Control lumbago, arthralgia, amenorrhea. " modern medicine study shows, Herba Lycopodii contains the alkaloid such as lycopodine, rod lycoclavanin alkali and terpenoid, sterol and acids, has cooling, hypotensive activity, can strengthen heart contraction dynamics, and excited smooth muscle, in addition with bacteriostasis.

Periostracum Cicadae: sweet in the mouth; Salty; Cool in nature. Enter lung; Liver Channel. Dispelling wind-heat; Rash sore-throat relieving; Removing nebula to improve visual acuity; Expelling wind and relieving convulsion. Cure mainly anemopyretic cold; Laryngopharynx swelling and pain; Cough hoarseness; Stupid rash is not saturating; Rubella pruritus; Cataract; Infantile convulsion is twitched; Tetanus. " detailed outline " carries: " controlling phlegm-accumulating vertigo, skin wind heat, varioliform exanthema is had an itch, tetanus and treat toxic swelling tumor, adult's aphonia, and children's's lockjaw sky hangs, frightened night cry of crying, swelling of the vulva. " modern medicine study confirms; Periostracum Cicadae has obvious convulsion, sedation, can block parasympathetic conduction on neck, be widely used in treatment tetanus, chronic Herba Urticae Cannabinae examine, suppurative otitis media, vasodilation; cough in addition with cough-relieving, particularly the effect coughed of itching of the throat.

Clear Fructus Solani melongenae: acrid in the mouth; Micro-hardship; Warm in nature. Return spleen; Stomach; Kidney channel. Warming middle-JIAO to relieve pain; Promoting flow of QI and blood; Relieving asthma; Diuresis. Cure mainly coldness and pain in the epigastrium; Food stagnation flatulence; Regurgitation is vomitted; Heatstroke is vomited and diarrhoea; Dysentery; Colic of cold type is suffered from abdominal pain; Asthma; Cold-damp dropsy; Dysuria; Turbid urine; Sore swollen toxin; Toothache; Arthralgia due to cold-dampnes; Traumatic injury. Modern medicine study proves: clear Fructus Solani melongenae has antiplatelet aggregative activity, resist myocardial ischemia and myocardial infarction effect, relieving asthma and anti-allergic effects, antibacterial action and litholytic effect.

Citrus aurantium L. var. amara Engl.: acrid in the mouth; Sweet; Micro-hardship; Property is put down. Regulate the flow of vital energy the chest stuffiness relieving; Stomach function regulating preventing or arresting vomiting. Cure mainly painful abdominal mass in the heart vexed; Abdominal distention; Anorexia; Nausea and vomiting. " Zhejiang Chinese medicine handbook ": regulating QI is soothing the liver, controls chest and diaphragm and gastral cavity space painful abdominal mass pain.

The present invention compared with prior art, has the advantages that

The present invention selects medical material monarch, minister, a left side, makes all reasons all standby, the property of medicine is suitable mutually auxiliary mutually, suit the remedy to the case for the cause of disease, there is effect of vigorate qi and replenish the blood, blood enriching and dryness moistening, promoting flow of QI and blood, blood circulation promoting and blood stasis dispelling, clearing away heat-damp and promoting diuresis, dispelling wind for relieving itching, removing toxic substances and promoting subsidence of swelling, removing obstruction in the collateral to relieve pain, stomach function regulating preventing or arresting vomiting, good absorbing effect, evident in efficacy, have no side effect and clinical adverse, higher to anaesthetizing postoperative pruritus pain cure rate according to clinical verification.

Detailed description of the invention

Below in conjunction with specific embodiment, the present invention is further elaborated.

Embodiment 1

The raw material of effective ingredient of the present invention forms and weight is:

Herba Taraxaci 70～88g, the Radix Astragali 67～85g, Radix Angelicae Sinensis 64～82g, Herba Hedyotidis Diffusae 60～78g,

Semen Sesami Nigrum 57～75g, Radix Codonopsis 53～72g, Folium Pini 50～68g, Fructus Mori 47～65g,

Caulis Trachelospermi 44～62g, the Rhizoma Atractylodis Macrocephalae 41～59g, Radix Glycyrrhizae 38～56g, Semen pini koraiensis 35～52g,

Caulis Polygoni Multiflori 32～48g, Radix Salviae Miltiorrhizae 29～44g, Herba Blumeae clarkei 26～40g, Cortex Dictamni 23～37g,

The Fructus Kochiae 20～34g, Rhizoma Corydalis 17～30g, Caulis Piperis Kadsurae 14～27g, river Cortex cinnamomi japonici (Ramulus Cinnamomi) 12～24g,

Herba Lycopodii 10～20g, Periostracum Cicadae 8～17g, clear Fructus Solani melongenae 5～14g, Citrus aurantium L. var. amara Engl. 2～10g.

The processing step of process for preparing medicine of the present invention is:

Usage and dosage: each 1 bag of every day 3 times, half an hour ante cibum takes after mixing it with water with boiled water, 3 days is 1 course for the treatment of, and Chinese medicine of the present invention is not taken by pregnant women.

Embodiment 2

Herba Taraxaci 73～85g, the Radix Astragali 70～82g, Radix Angelicae Sinensis 67～78g, Herba Hedyotidis Diffusae 63～75g,

Semen Sesami Nigrum 60～72g, Radix Codonopsis 56～68g, Folium Pini 53～65g, Fructus Mori 50～62g,

Caulis Trachelospermi 47～58g, the Rhizoma Atractylodis Macrocephalae 44～56g, Radix Glycyrrhizae 41～53g, Semen pini koraiensis 38～48g,

Caulis Polygoni Multiflori 35～45g, Radix Salviae Miltiorrhizae 32～40g, Herba Blumeae clarkei 29～37g, Cortex Dictamni 26～34g,

The Fructus Kochiae 23～31g, Rhizoma Corydalis 20～27g, Caulis Piperis Kadsurae 17～24g, river Cortex cinnamomi japonici (Ramulus Cinnamomi) 15～21g,

Herba Lycopodii 13～17g, Periostracum Cicadae 10～15g, clear Fructus Solani melongenae 7～11g, Citrus aurantium L. var. amara Engl. 4～7g.

The process for preparing medicine processing step of the present embodiment and usage and dosage and embodiment 1 are identical.

Embodiment 3

Herba Taraxaci 79g, Radix Astragali 76g, Radix Angelicae Sinensis 73g, Herba Hedyotidis Diffusae 70g,

Semen Sesami Nigrum 66g, Radix Codonopsis 63g, Folium Pini 59g, Fructus Mori 56g,

Caulis Trachelospermi 53g, Rhizoma Atractylodis Macrocephalae 50g, Radix Glycyrrhizae 47g, Semen pini koraiensis 43g,

Caulis Polygoni Multiflori 40g, Radix Salviae Miltiorrhizae 36g, Herba Blumeae clarkei 33g, Cortex Dictamni 30g,

Fructus Kochiae 27g, Rhizoma Corydalis 24g, Caulis Piperis Kadsurae 21g, river Cortex cinnamomi japonici (Ramulus Cinnamomi) 18g,

Herba Lycopodii 15g, Periostracum Cicadae 12g, clear Fructus Solani melongenae 9g, Citrus aurantium L. var. amara Engl. 5g.

Clinical data:

1, case selection

Selecting the postoperative pruritus pain patients 80 example clinical observation of anesthesia that my institute sees and treat patients, patient is randomly divided into two groups.

Treatment group 40 example, wherein male 26 example, women 14 example, 13～56 years old age, 37.4 years old mean age. Matched group 40 example, wherein male 27 example, women 13 example, 14～57 years old age, 36.9 years old mean age. Two groups of qualifications and record of service are basically identical, without significant difference, have comparability.

2, treatment group patient takes medicine of the present invention, and each 1 bag of every day 3 times, half an hour ante cibum takes after mixing it with water with boiled water, within 3 days, is 1 course for the treatment of, takes 1～2 course for the treatment of. Matched group, according to the symptom anaesthetizing postoperative pruritus pain being diagnosed to be, gives the antihistaminic antipruritic agent such as chlorphenamine, Cyproheptadine respectively to the ill and low dose of analgesic drug product is treated.

3, efficacy determination:

(1) cure: anaesthetize the ill symptomses such as the health pruritus caused and postoperative pain and be wholly absent.

(2) take a turn for the better: anaesthetize the ill symptomses such as the health pruritus caused and postoperative pain and substantially alleviate.

(3) invalid: symptom is with treating front no significant difference.

4, result

Treatment group cure rate 62.5%, total effective rate 95%, matched group cure rate 52.5%, total effective rate 85%, two groups of comparitive study, difference has a statistical significance (P < 0.05), therefore treatment group is substantially better than matched group for the curative effect of primary disease.

1 liang of table group patient clinical comparitive study

Model case is illustrated:

1, grandson's ××, man, 27 years old. This patient, because suffering from acute appendicitis, carries out anesthesia surgery, and postoperative health occurs pruritis often, and position is not fixed, and doctor trained in Western medicine medicine for external use is inconvenient to use, and after taking 1 course for the treatment of of Chinese medicine of the present invention, pruritis is wholly absent, and fully recovers.

2, what ××, female, 18 years old. When this patient is because of thoracic surgery, carry out surgery anesthesia, postoperative health occur pruritus, pain, feel sick etc. ill symptoms, after taking 1 course for the treatment of of Chinese medicine of the present invention, above-mentioned symptom substantially alleviates, and follows the doctor's advice after continuing to take 1 course for the treatment of, above-mentioned symptom is wholly absent, and fully recovers.

3, Lee's ××, man, 39 years old. This patient carries out Postoperative and anesthesia because of wound first aid, and pruritis occurs in health, and position is not fixed, and pruritus is hard to bear, and after taking 1 course for the treatment of of Chinese medicine of the present invention, pruritis is wholly absent, and fully recovers.

4, what ××, man, 45 years old. This patient carries out Postoperative and anesthesia because of exodontia, and pruritis occur in face, cervical region, and after taking 1 course for the treatment of of Chinese medicine of the present invention, pruritis is wholly absent, and fully recovers.

In anesthesia recovery room, the major issue that postoperative pruritus pain is patient and Anesthetist faces. Chinese medicine of the present invention, through long-term clinical practice, is suited the remedy to the case according to the cause of disease, and the Radix Astragali, Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae in side, Radix Angelicae Sinensis can vigorate qi and replenish the blood; Fructus Mori in side, Semen pini koraiensis, Semen Sesami Nigrum can blood enriching and dryness moistening, loosening bowel to relieve constipation; Radix Salviae Miltiorrhizae in side, Rhizoma Corydalis can blood circulation promoting and blood stasis dispelling, regulating QI to relieve pain; Fang Zhongchuan Cortex cinnamomi japonici (Ramulus Cinnamomi), clear Fructus Solani melongenae can dispelling cold by warming the meridian, promoting flow of QI and blood; Herba Taraxaci in side, Herba Hedyotidis Diffusae can heat-clearing and toxic substances removing; Caulis Piperis Kadsurae in side, Caulis Polygoni Multiflori can tranquilizing by nourishing the heart, dispelling wind and removing obstruction in the collateral; Herba Lycopodii in side, Caulis Trachelospermi can dredge the meridian passage, reducing swelling and alleviating pain; Periostracum Cicadae in side, Cortex Dictamni, the Fructus Kochiae, Folium Pini, Herba Blumeae clarkei can clearing away heat-damp and promoting diuresis, dispelling wind for relieving itching; In side, Citrus aurantium L. var. amara Engl. can be regulated the flow of vital energy the chest stuffiness relieving, stomach function regulating preventing or arresting vomiting; In side, Radix Glycyrrhizae can relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription; In side, all medicines share the effect that can play vigorate qi and replenish the blood, blood enriching and dryness moistening, promoting flow of QI and blood, blood circulation promoting and blood stasis dispelling, clearing away heat-damp and promoting diuresis, dispelling wind for relieving itching, removing toxic substances and promoting subsidence of swelling, removing obstruction in the collateral to relieve pain, stomach function regulating preventing or arresting vomiting altogether, can benefiting vital QI and blood, make venation unimpeded, QI and blood is smooth, improving microcirculation around, reduce inflammation reaction, promotes wound healing, elimination scalpel edge swells and ache, relieving itch, good absorbing effect, evident in efficacy, have no side effect and clinical adverse, higher to anaesthetizing postoperative pruritus pain cure rate according to clinical verification.

Claims

1. one kind for anaesthetizing the instant particles as Chinese medicine of postoperative pruritus pain relief, it is characterised in that raw material composition and the parts by weight of making described effective ingredient are:

2. a kind of instant particles as Chinese medicine for anaesthetizing postoperative pruritus pain relief according to claim 1, it is characterised in that make described effective ingredient raw material composition and parts by weight be:

3. a kind of instant particles as Chinese medicine for anaesthetizing postoperative pruritus pain relief according to claim 1, it is characterised in that make described effective ingredient raw material composition and parts by weight be:

4. the preparation method of a kind of instant particles as Chinese medicine for anaesthetizing postoperative pruritus pain relief according to claims 1 to 3, it is characterised in that comprise the following steps that: